<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCV7</accession>
    <name>B1KCV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0031"/>
    <dbReference type="EnsemblBacteria" id="ACA84332">
        <property type="protein sequence ID" value="ACA84332"/>
        <property type="gene ID" value="Swoo_0031"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0031"/>
    <dbReference type="eggNOG" id="ENOG50332MP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1842156_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010862">
        <property type="entry name" value="DUF1493"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07377">
        <property type="entry name" value="DUF1493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="16446" checksum="EFF70DD478EC6A58" modified="2008-04-29" version="1">MALGIPLDIAEILNFVAIESGTKIEKVHLNSNISDELGIVGDDFHELIEAYSNKYHVNMDEYLWYFHSEDEGVNIWSFIFKPPWKKVEKIPITPQMLLNFAIKGKWLVVYPEHKVPTNRNDITYSNCLWLVLIIGFLVACYT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ4</accession>
    <name>PEPQ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Xaa-Pro dipeptidase</fullName>
            <shortName evidence="1">X-Pro dipeptidase</shortName>
            <ecNumber evidence="1">3.4.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Imidodipeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Proline dipeptidase</fullName>
            <shortName evidence="1">Prolidase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pepQ</name>
        <name type="ordered locus">Swoo_0022</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Splits dipeptides with a prolyl residue in the C-terminal position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of Xaa-|-Pro dipeptides. Also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro.</text>
            <dbReference type="EC" id="3.4.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322672.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCZ4"/>
    <dbReference type="SMR" id="B1KCZ4"/>
    <dbReference type="STRING" id="392500.Swoo_0022"/>
    <dbReference type="MEROPS" id="M24.003"/>
    <dbReference type="EnsemblBacteria" id="ACA84323">
        <property type="protein sequence ID" value="ACA84323"/>
        <property type="gene ID" value="Swoo_0022"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0022"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050675_0_0_6"/>
    <dbReference type="OMA" id="DFWHKVA"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016795">
        <property type="term" value="F:phosphoric triester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102009">
        <property type="term" value="F:proline dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01279">
        <property type="entry name" value="X_Pro_dipeptid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022846">
        <property type="entry name" value="X_Pro_dipept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0224">Dipeptidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000140332" description="Xaa-Pro dipeptidase">
        <location>
            <begin position="1"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01279"/>
        </source>
    </evidence>
    <sequence length="439" mass="49922" checksum="2E3DCC354871BF34" modified="2008-04-29" version="1">MDQLANHFKSHIAELNHRVAEIISRENLSGLVIHSGQPHRQFLDDMDYPFKVNPHFKAWLPILDNPHCWLLVNGRDKPQLIFYRPVDFWHKVADLPDAFWAEHVEIKLLTKADKVAELLPSDISQWAYIGEHLDVAEVLGFKTRNPDAVMSYLHYHRASKTQYELCCLRNANEIAVKGHLAAKNAFFNGGSEFEIQQEYLTATNQGENEVPYGNIVALNENAAILHYTKLESVRPESRHSFLIDAGANFFGYASDITRTYAFEKNIFSELIEAMDKMQQEIISMMRPGVKYVDLHIATHQKLAKILVDFDIASGEPQSLVDQGITNVFFPHGLGHMLGLQVHDMGGFLHDERGTHIAAPDAHPFLRCTRTLAANQVLTIEPGIYIIDSLLNELKQDSRKKQVNWQTVDLLRPFGGIRIEDNVIVHADQNENMTRDCGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA9</accession>
    <name>B1KDA9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323258.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0614"/>
    <dbReference type="EnsemblBacteria" id="ACA84910">
        <property type="protein sequence ID" value="ACA84910"/>
        <property type="gene ID" value="Swoo_0614"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0614"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052179_0_0_6"/>
    <dbReference type="OMA" id="EGTRYIQ"/>
    <dbReference type="OrthoDB" id="1108234at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="161"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="503" mass="56788" checksum="F2491386D134C1CD" modified="2008-04-29" version="1">MVNSESVTAKRQRGAAAIYLVFLLIPLFGMVFLALEGTRYIQKKNRLGDATEAASLAVSMANRDDKGYETQLAKDYISSYMRNIKEISQVKVERKEDIDHYPMADGSFEDREYTQYRVTAKTEHTSWLHSDLIPSFKETETLANRALARAYPEYLGDRDVDIVFVSDFSGSMKGSRINSLKDAITEISNEILVPRDGETEIRNRIALVPYNMRVVEGDSGRSVCMTQLKYRNPSGKTGSNYTNYESINWREWANKSYNQVSSCVSNSRKCNGLPGPRADARTIKSVVNDAPSSYRSSKWPDSSNWIDYSRSVDQLFNENSNNVQHHPSYQRLYSGSMCNGKFWTVPLTNQKSEIMKVNQMSPDGGTSVYQGLLRGAQILDKGRPVNPNEEELEEYNKRLKMILILSDGMESPYESTFSKLVNNYGMCNKIRAQFNDGELPLHMGVIGIKFSASGQNAFKNCVGADNIIDVNDLDDLIQEILDLIKKGAKSDGISKLYYRHTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF1</accession>
    <name>B1KDF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arginine N-succinyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.109</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.109" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323299.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0656"/>
    <dbReference type="EnsemblBacteria" id="ACA84952">
        <property type="protein sequence ID" value="ACA84952"/>
        <property type="gene ID" value="Swoo_0656"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0656"/>
    <dbReference type="eggNOG" id="COG3138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057655_0_0_6"/>
    <dbReference type="OMA" id="CNDYTGV"/>
    <dbReference type="OrthoDB" id="972674at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008791">
        <property type="term" value="F:arginine N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007041">
        <property type="entry name" value="Arg_succinylTrfase_AstA/AruG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017650">
        <property type="entry name" value="Arginine_N-succinylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04958">
        <property type="entry name" value="AstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03243">
        <property type="entry name" value="arg_catab_AOST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03244">
        <property type="entry name" value="arg_catab_AstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="339" mass="38059" checksum="F867FBB0FBD1FC7D" modified="2008-04-29" version="1">MLIIRPIRSSDFEALYQIAEESGHGFTSLPVNEELLRNKIARVEASFLKEVDKPFDEGYLMVLEDTETGEVVGTCGIEAAVGMEDAFYHYRLGTEVYHSEQIEVRNEVETLTLCHDYTGAAELCTLFLRGSYRKNSNGRMLSRSRFLFLAQHKERFGETVIAEMRGESDKEGNSPFYDWLQKHFLGIDFVEADYLSGLGQKAFMAEMMPKNAVYVCLLPEDAQKVIGEVHTNTRPALNLLQAEGFRCRGYVDIFDGGPTVECNINDIRGVRESRLLTVTIGEPPESDTSYIISNTQLANYRATSAKLLVSEENDEVVISPELATGLLLEQGDQIRILAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF5</accession>
    <name>B1KDF5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323303.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0660"/>
    <dbReference type="EnsemblBacteria" id="ACA84956">
        <property type="protein sequence ID" value="ACA84956"/>
        <property type="gene ID" value="Swoo_0660"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0660"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_6"/>
    <dbReference type="OMA" id="VWGYDAY"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="25570" checksum="F34107CE9EA481FE" modified="2008-04-29" version="1" precursor="true">MKLLLVEDNALLVEELEKQLKQAGYVTDVTDKASEADYLLKETNYDCVILDIGLPDGNGLELLSRWRNQGIHTPVIMLTARSQWHEKVEGFNAGADDYLGKPFHTQELLVRINALIQRAHGKANSPSKELSYAGITLDEDQQSVMVQEEKFELTAMEFRLLKIFIMSPKKLLSKAQLTDKLYQFDDEKESNVVEVYVTHLRKKLGKTSIETRRGQGYIFHGIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDI1</accession>
    <name>B1KDI1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NnrS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323329.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0686"/>
    <dbReference type="EnsemblBacteria" id="ACA84982">
        <property type="protein sequence ID" value="ACA84982"/>
        <property type="gene ID" value="Swoo_0686"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0686"/>
    <dbReference type="eggNOG" id="COG3213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041785_2_0_6"/>
    <dbReference type="OMA" id="HVHEMLY"/>
    <dbReference type="OrthoDB" id="791105at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010266">
        <property type="entry name" value="NnrS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05940">
        <property type="entry name" value="NnrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="431" mass="47452" checksum="296A4923F2F48EB7" modified="2008-04-29" version="1">MSKTLHSINEPAKQQVSKARLNQQLHSTGELSGAEKTHLPPKLLSITQQPLWDLAFRPWFLAGTLSSVLSVGIWILFLHGYLPTLANSGLTPVAWHIHEMLFGFGANIAVAFLLTAAQTWTNKRSINGGALLTLTLIWLMVRVLLWSEDSRIQVLALVLQAGWWLACIGFLASMVIRAKSKRNYQFIPLLSVMMLLNLSFLIADFSGHTELALHLARTAILTFGLLVGIVGGRVIPFFTGRGADNAQVKATPILDKLLPVVTIIGIGIFFTGHFIALPFTPAVALISAGIIHLLRLWHWDPLSTRKVPLLWSLQLAYLALGLGLVALGISYHIDLVRFADALHLITVGTIGGMILAMIARVSLGHTGRPLKPHPSLNIAFALMFIGTLVRFILPLLQMPIMAWDISAICWITAFSIFIWHYTRILMSARAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDK9</accession>
    <name>B1KDK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2122</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324751.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2122"/>
    <dbReference type="EnsemblBacteria" id="ACA86406">
        <property type="protein sequence ID" value="ACA86406"/>
        <property type="gene ID" value="Swoo_2122"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2122"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="RVRNQFP"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022305">
        <property type="entry name" value="Response_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03787">
        <property type="entry name" value="marine_sort_RR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="132"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="132"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="231" mass="26318" checksum="14DD10707EF8ACAF" modified="2008-04-29" version="1">MKRIAIVEDEAAIRENYKEVLQQQGYSVQAYANRPSAMQAFSTRLPDLAIIDIGLEDEIDGGFTLCQSLRAMSSNLPIIFLTARDSDFDTVCGLRLGADDYLSKDVSFPHLIARLAALFRRAELQGKSLEVENLLERGALTIDANRMQVFWNQVPIELTVTEFWMVHSLAKRPGHVKNRQDLMQEAKIFVDDSTITSHVKRIRKKFIAQDAEFDCIDTVYGMGYRWEPQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDY4</accession>
    <name>B1KDY4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ornithine cyclodeaminase</fullName>
            <ecNumber evidence="1">4.3.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.1.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326318.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3726"/>
    <dbReference type="EnsemblBacteria" id="ACA87986">
        <property type="protein sequence ID" value="ACA87986"/>
        <property type="gene ID" value="Swoo_3726"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3726"/>
    <dbReference type="eggNOG" id="COG2423">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042088_1_2_6"/>
    <dbReference type="OMA" id="AVKAFTY"/>
    <dbReference type="OrthoDB" id="1193876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008473">
        <property type="term" value="F:ornithine cyclodeaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="PTHR13812"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001439">
        <property type="entry name" value="CryM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="318" mass="35355" checksum="3970EB60563E0803" modified="2008-04-29" version="1">MIVINAEEVHNTLNFPVLINELRDTFSKPAGMPQRQVYSLDEATSHNDAFALLPSWNEKTIAVKAFTYFPENPRKNQQLKSLHSKIMIFDRKTGAPQALVDGTSVTYWRTAAISALGSSYLSRKDSKKLLIFGTGNLASFMALAHASVRPITQITVWGRNQDKAQATIEKIRNKRPDIEVILSKSVEHSVREADIISCATGSPTPLFDSNWVAPGTHTDFVGNHNHDRRECDSKLVLRSAVYVDSKINVFAEAGELLIPVSEGEYQLESVKGELAQLCKDEIKGREDEQQITLFKTVGTALADLVGAQLVYSQLKHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDZ3</accession>
    <name>B1KDZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326327.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3736"/>
    <dbReference type="EnsemblBacteria" id="ACA87995">
        <property type="protein sequence ID" value="ACA87995"/>
        <property type="gene ID" value="Swoo_3736"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3736"/>
    <dbReference type="eggNOG" id="ENOG5031WU7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1061278_0_0_6"/>
    <dbReference type="OMA" id="MFMAEFV"/>
    <dbReference type="OrthoDB" id="1663423at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="24675" checksum="925E9787C87BF14F" modified="2008-04-29" version="1" precursor="true">MFCYKPPKKSGNKGGIELLAVVVLISAMVTPSALGGSSAGLTGSIAHNHKLSIFDQKLSFTLPEDWKLAFSEKQNTMFSAEFTPVSDELRDWSSLFCVQGFKGLADSFSPETFLDSIAATYEESCTGEITYQKLGESDIDGYSGFTAIIGCSHMPNTHKATQFNAKSYSSDPKGEIGHYTAISGEQDMYLLHQSMRGEVFNAETPPLEPANYREFMATIAPYGLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE60</accession>
    <name>B1KE60_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323393.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0751"/>
    <dbReference type="EnsemblBacteria" id="ACA85046">
        <property type="protein sequence ID" value="ACA85046"/>
        <property type="gene ID" value="Swoo_0751"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0751"/>
    <dbReference type="eggNOG" id="ENOG5030990">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2865347_0_0_6"/>
    <dbReference type="OMA" id="MEICRDA"/>
    <dbReference type="OrthoDB" id="2096443at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="62" mass="6822" checksum="49B80C23DBD77F48" modified="2008-04-29" version="1">MPKTSKIRGQASVEYLVVCAALVAALLTPIDNNSDVMDLCIETLREWYTAFAYSKSLSVLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB4</accession>
    <name>B1KEB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324836.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2210"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86492">
        <property type="protein sequence ID" value="ACA86492"/>
        <property type="gene ID" value="Swoo_2210"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2210"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_2_3_6"/>
    <dbReference type="OMA" id="PNGEKWA"/>
    <dbReference type="OrthoDB" id="1573900at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="55"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="586" mass="66744" checksum="C5D97A999DDC3C6D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEC3</accession>
    <name>B1KEC3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4266 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2220"/>
    <dbReference type="EnsemblBacteria" id="ACA86501">
        <property type="protein sequence ID" value="ACA86501"/>
        <property type="gene ID" value="Swoo_2220"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2220"/>
    <dbReference type="eggNOG" id="ENOG5031EFC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177704_0_2_6"/>
    <dbReference type="OMA" id="LMLNDHI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025362">
        <property type="entry name" value="DUF4266"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14086">
        <property type="entry name" value="DUF4266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766988" description="DUF4266 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4266" evidence="2">
        <location>
            <begin position="29"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="78" mass="8568" checksum="B25702C79028852F" modified="2008-04-29" version="1" precursor="true">MMAICGKWVKAKFLFLFVLLCGGCSTLGVQPWERDQFAREDMALDNEKLDLMLNDHIYFSKEGTSGGRTQGGGGCGCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEG1</accession>
    <name>B1KEG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324882.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2258"/>
    <dbReference type="EnsemblBacteria" id="ACA86539">
        <property type="protein sequence ID" value="ACA86539"/>
        <property type="gene ID" value="Swoo_2258"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2258"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052000_0_0_6"/>
    <dbReference type="OMA" id="RWMNDRD"/>
    <dbReference type="OrthoDB" id="538961at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022478">
        <property type="entry name" value="ABC_transptr_sub-bd_PQQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03863">
        <property type="entry name" value="PQQ_ABC_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764760" evidence="1">
        <location>
            <begin position="25"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="400" mass="45272" checksum="E7C678D0C70BD74D" modified="2008-04-29" version="1" precursor="true">MRKTNIRLKCCCFLSLFYLSPLLAASDNSVIEININYLKLNQAKSPALSNVIDMARDSGERGAELAVNDSNTTGKFLKQNFELNYVEFDSAKVLLAHFSAEVNAGQSYFILDVPAELLSKADEWAEDKQLLIFNVNETSDLLREKQCLSSTLHTVPSDAMRSDAIAQWLLSRRFNKVLLVSGKNKQDMALNNSFKRAAKRFGIKILDEKQWRFDTDLRRSAQQEVPLFTQTRDDYDVVYVADRTKDFAEYLPFNTYLPRPVVGSAGLEALSWHFTIEQWGAAQLQNRFNALAERNMNELDFSAYLAVRSIAEAVHQQKTASPIKIINYIKSDDFQLAAYKGRKLSYRHWSGQLRMPIALVQPHGVVSLSPQAGVLHPVTELDTLGFDRQESQCAGQKESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEP0</accession>
    <name>B1KEP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PepB aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3796</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.23" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326386.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3796"/>
    <dbReference type="EnsemblBacteria" id="ACA88055">
        <property type="protein sequence ID" value="ACA88055"/>
        <property type="gene ID" value="Swoo_3796"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3796"/>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013734_7_1_6"/>
    <dbReference type="OMA" id="QWAFAQG"/>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008330">
        <property type="entry name" value="Pept_M17_PepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12404">
        <property type="entry name" value="DUF3663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036388">
        <property type="entry name" value="Ctsl_amnpptdse_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="7">
        <location>
            <begin position="272"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="425" mass="45093" checksum="6EDA38D9933AE5AF" modified="2008-04-29" version="1">MTDVMTVTLTKDAPAAHWGNADVTFENNQSVIHLQGGDELRQIQQAARKLRNQGITKLALEGELWDLHTQWALAQGFATAKSVPEISWTGDENTQQALTDRLTSASFARHLINETPENLAPVKLAILAAHWLSEIGGDKVSYRVIEGAELLEEKWVGIHAVGRGSERPPAMLELDYNPLGEDAPVSVALVGKGITFDSGGYSIKASEGMLGMKCDMGGAATVTASLGLAMKQGLNKRVKLFLCCAENLISGHAYKLGDVITYKNGVSVEVVNTDAEGRLVLADGLQAACETGAPLVIDAATLTGAAVMAVGTNYNAIFSPKSEVLAMAQAKASEVGERVWPLPLDPWHRDMCPSPYADTANSRPMKGGGAGGASNAAGFLWRFVSPEVNWLHMDLASAFADSPNSLWAAGGTSHGMLTITALLQD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEP6</accession>
    <name>PANB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="1">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="1">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">panB</name>
        <name type="ordered locus">Swoo_3802</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326392.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KEP6"/>
    <dbReference type="SMR" id="B1KEP6"/>
    <dbReference type="STRING" id="392500.Swoo_3802"/>
    <dbReference type="EnsemblBacteria" id="ACA88061">
        <property type="protein sequence ID" value="ACA88061"/>
        <property type="gene ID" value="Swoo_3802"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3802"/>
    <dbReference type="eggNOG" id="COG0413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036645_1_0_6"/>
    <dbReference type="OMA" id="VLVWTDM"/>
    <dbReference type="OrthoDB" id="916845at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000097007" description="3-methyl-2-oxobutanoate hydroxymethyltransferase">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="45"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <sequence length="264" mass="28320" checksum="F4D56F0545B8738F" modified="2008-04-29" version="1">MSKITSSTLLKFKQEGKKFTALTAYDASFASAFDSEGVDVLLVGDSMGMVLQGHDDTLPVSVEDIAYHTRCVRRGIKRSLLISDMPFMSYATPEQAMRNATALMQAGANMVKVEGGHWLLETVTMLTERGIPVCAHLGLTPQSVHVFGGFKVQGRDADNAQRILDEAKALEAAGAQLLVVECIPAALAQTISEALTIPVIGIGAGAGTDGQILVMHDVLGISSGYIPRFSKNYLKQTGEIREAIRAYIDEVEKGVFPGSDHTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX6</accession>
    <name>B1KEX6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323474.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0832"/>
    <dbReference type="EnsemblBacteria" id="ACA85127">
        <property type="protein sequence ID" value="ACA85127"/>
        <property type="gene ID" value="Swoo_0832"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0832"/>
    <dbReference type="eggNOG" id="ENOG5031WXP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1531515_0_0_6"/>
    <dbReference type="OMA" id="MEQEVSF"/>
    <dbReference type="OrthoDB" id="1806108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="171" mass="18400" checksum="4997437B3F69297F" modified="2008-04-29" version="1">MQFKRLVVPALFTFGLGGCGYFDGDEKQQLEQAWLAQNAQLQQVIEQIRSQGIEAVANGAEVGSVAACVASKLEMDPLGELVNVEGALVESAKIAELLSELEGLMEQDFSLENISGLLQKGADAAAYAKQIIAAQGLERGLEHLQQMADSSREFASEDLGAHFQQLLSECQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF45</accession>
    <name>SERC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoserine aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphohydroxythreonine aminotransferase</fullName>
            <shortName evidence="1">PSAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">serC</name>
        <name type="ordered locus">Swoo_2307</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="1">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324928.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KF45"/>
    <dbReference type="SMR" id="B1KF45"/>
    <dbReference type="STRING" id="392500.Swoo_2307"/>
    <dbReference type="EnsemblBacteria" id="ACA86586">
        <property type="protein sequence ID" value="ACA86586"/>
        <property type="gene ID" value="Swoo_2307"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2307"/>
    <dbReference type="eggNOG" id="COG1932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034866_0_2_6"/>
    <dbReference type="OMA" id="GYRASMY"/>
    <dbReference type="OrthoDB" id="996960at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PTHR43247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01364">
        <property type="entry name" value="serC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0032">Aminotransferase</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0718">Serine biosynthesis</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000203577" description="Phosphoserine aminotransferase">
        <location>
            <begin position="1"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="240"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00160"/>
        </source>
    </evidence>
    <sequence length="364" mass="40387" checksum="22271C00F4FE75BD" modified="2008-04-29" version="1">MSATYNFCAGPAMLPQAVMEKAQSELLDWNGLGTSVMEISHRSKEFIALTEQAEIDLRELMSIPSNYHVLFMHGGGRGQFSAVVNNFLGNNGKALYLVDGSWSSAAVDEAKKLAGETQIDTLNIVEKDGATSRVSIPNLKELDQDYRYLHYCPNETVDGIEIFEELDSPWPIVADMSSNIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVKDELLQLPQLPQSSIMDYRLGVKHGSMYNTPPTFAWYLAAEVFKWLKSSGGVGEVQKANERKAGTLYQFIDSCDFYENRVAVENRSVMNVTFYLKDEALNDEFIKQAKAVGLVALKGHRSVGGMRASIYNAMPLEGVEKLVEFMTDFANKNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF84</accession>
    <name>B1KF84_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324967.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2346"/>
    <dbReference type="EnsemblBacteria" id="ACA86625">
        <property type="protein sequence ID" value="ACA86625"/>
        <property type="gene ID" value="Swoo_2346"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2346"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_1_0_6"/>
    <dbReference type="OMA" id="FNWLYNL"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="447" mass="47748" checksum="55638555F29D4B19" modified="2008-04-29" version="1">MTQNITSHPQDHRVMGFWRVWALAVGCAIGSGIFMMPTLLAPYGMLGLGSWLVAGAGTVLIALTFARLATRMPKTGGLYIYADSGLGSMAGFIVGWCYWISCLTAVASVAIAFISYLSSYVPILAEHNQAGLIACLGLVWLIIGLNIRSIKGSSIFQVITTILKIVPLLVLAVLGLVNMQPEMLPEYNPTELSPIAAISAATMLVMWSFLGIESATVPAGNVIKPEKTIPRAIIASVLTILVLYILVSLAVNLTVPANELKNSTAPFKLAAERLMGPVGALVVTLGALLSTLGSLNANTLMCGQMPMAIATNGLFPKQFKRLSKNGTPVFGLLVSGAIVSVLLVMNYTKGLIGAFTFLVMMATLATLMAYTLCAIAEFYFLKQDKPSAARNRAIVLGIGTFVYSLFCILGAGQEIVFYSFLLILLGLPVYALQRKPETNMSEELFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFD2</accession>
    <name>B1KFD2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325015.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2394"/>
    <dbReference type="EnsemblBacteria" id="ACA86673">
        <property type="protein sequence ID" value="ACA86673"/>
        <property type="gene ID" value="Swoo_2394"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2394"/>
    <dbReference type="eggNOG" id="ENOG502Z7JD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086975_0_0_6"/>
    <dbReference type="OMA" id="DLHKDSW"/>
    <dbReference type="OrthoDB" id="1737534at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021372">
        <property type="entry name" value="DUF2989"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11207">
        <property type="entry name" value="DUF2989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="278" mass="32092" checksum="AC705B8B3DCBC917" modified="2008-04-29" version="1" precursor="true">MSRSVVIFTSFFSIIVFSALLGCDNVGNNNTICKNNPELCADLHKDSWCRYEKSDLLKSRLRLKHEQSPPGKDLYHHLIHLEKYNKCIELASGVQHILHPERTNDRTRAFGLSAQSLAELQVSTKESNDPYLVYYHWTRFNDQVAQAKILRAERLNLIDDIEILAGIASYYQKYDPAKARQVYLAVFNKSNEENFNPEWLLGLANTYQKLNDLEMTYLLSRANILMSENQVSEKSMLMLINGDSELKIFLDEHAEELVDSLQSGSYHSSKIRRILEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFD9</accession>
    <name>B1KFD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326444.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3856"/>
    <dbReference type="EnsemblBacteria" id="ACA88114">
        <property type="protein sequence ID" value="ACA88114"/>
        <property type="gene ID" value="Swoo_3856"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3856"/>
    <dbReference type="eggNOG" id="ENOG502Z9KH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_813530_0_0_6"/>
    <dbReference type="OrthoDB" id="1009280at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="341" mass="38109" checksum="696986A35800656D" modified="2008-04-29" version="1">MDIKKYTGVVSGWQGGFEQSNPDFAYPNPNLTSLPMLDNMANIDLLQRQQAVKWPEFSWETEKGNSNPKRCYQMFAPDISRLGYTDTGRVYSIICPQQGISSPSLGTLNVEVTVTGQRGWVDETDREIAADMSVVGKIWFSPSAVQKPIVKLLWSHFEKSKQPFPSEKSKAIVVYTHKVGQAEQPIFPLLSGESTGFDIPEFAKHPQAWSVGNLGVEIGAPLKTGYPVVDAFNKLIMDVFNLGSGNMLQVGNVLTWNVWFTEPELVDTEEWRTHAQRWRESIDADHGSPDGPGTQARYFDGTPFKPDFDLIKELEKSKIGDFLGNLEGDIKEGISECLKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ2</accession>
    <name>B1KFQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323565.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0925"/>
    <dbReference type="EnsemblBacteria" id="ACA85218">
        <property type="protein sequence ID" value="ACA85218"/>
        <property type="gene ID" value="Swoo_0925"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0925"/>
    <dbReference type="eggNOG" id="ENOG502ZUT3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1502873_0_0_6"/>
    <dbReference type="OMA" id="GCMGQMG"/>
    <dbReference type="OrthoDB" id="1535484at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021768">
        <property type="entry name" value="DUF3332"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11810">
        <property type="entry name" value="DUF3332"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="19165" checksum="E417DBEB61847B0E" modified="2008-04-29" version="1" precursor="true">MKKTLISITLATLLSTQLTGCMGQMGLSAMVTKGNLSVVDNRFGRAGLFMLLSPVYGLTATADLFIFNSIEFWTGTNPITKRSPAVVDMPVEAIFKVNPHLNKELTKAPLPEIKLTNATMEATSEDTLVMTLNFDDGSQQLMSGKKSGEQVDFYLDNEFIARVSIEDLANYSKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG18</accession>
    <name>B1KG18_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Redoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325067.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2448"/>
    <dbReference type="EnsemblBacteria" id="ACA86725">
        <property type="protein sequence ID" value="ACA86725"/>
        <property type="gene ID" value="Swoo_2448"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2448"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132019_0_0_6"/>
    <dbReference type="OMA" id="YRGKHCP"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="5"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="176" mass="19346" checksum="9F102AEB3683B98D" modified="2008-04-29" version="1">MTTKLIAGASFPSIELLSINDGKVTLGKPQNGADWQMVIVYRGKHCPLCTRYLNEVEKLKLEFLKLGVDIIAVSADSLEQARTHIEQLDVSYPIAYGLTVAQMQQLGLYISNPRSAQETDHPFAEPGLFVVNEKGLAQVIDISNGPFVRPELGALLSGLGFIRNPENNYPIRGTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB4</accession>
    <name>B1KGB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c oxidase accessory protein CcoG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3994</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326580.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3994"/>
    <dbReference type="EnsemblBacteria" id="ACA88251">
        <property type="protein sequence ID" value="ACA88251"/>
        <property type="gene ID" value="Swoo_3994"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3994"/>
    <dbReference type="eggNOG" id="COG0348">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032118_0_0_6"/>
    <dbReference type="OMA" id="HCCPYAR"/>
    <dbReference type="OrthoDB" id="1230380at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014116">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_FixG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032879">
        <property type="entry name" value="FixG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13746">
        <property type="entry name" value="Fer4_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11614">
        <property type="entry name" value="FixG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02745">
        <property type="entry name" value="ccoG_rdxA_fixG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="287"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="496" mass="56730" checksum="0A11156F87F843B4" modified="2008-04-29" version="1">MSNNKTSHNNIDPVTASSAQAVHRYPAPEQRIEFREIPISPAPQSVKHSKKTPLASGKIHIREQKGRFQRIRTATNSLLVILFFLLPFISYQGHQAILFNLSEQQFIFFGTTLWPQDFTVLAWVFIAAAFLLFFTTVFWGRVWCGYLCPQTAWTFMYVWIETRLEGNQNKRIALDKAPWTRQKIVKRVAKHTAWGLTALLTGCAFIAYFVPARELYSDIFSLEASFWVTTWVWFFAICTYLNAGWMREQMCLHCCPYSRFQSVMFDANTKTVTYDANRGESRGARKRKQETELGDCVDCHLCVDVCPTGIDIRNGLQYECINCGACVDTCNQTMDKFGYQKNLISYVSENSLKGKSQPIYTSLKFIGYGLSAFIMLVVIGVDMANKSDIQLNVLRDRQNLYRETAQSQIENSYTLKIRNKTQQTRQYRLSIDKPQLMLVGSAELVIKPGEQLDYPVTLKTDTDQLMSTRTPITFSVTDISQTDSSVSQQSNFFGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGH3</accession>
    <name>B1KGH3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ThrE_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1008</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323648.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1008"/>
    <dbReference type="EnsemblBacteria" id="ACA85301">
        <property type="protein sequence ID" value="ACA85301"/>
        <property type="gene ID" value="Swoo_1008"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1008"/>
    <dbReference type="eggNOG" id="COG3610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117642_1_0_6"/>
    <dbReference type="OMA" id="IPIEWAT"/>
    <dbReference type="OrthoDB" id="1567942at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE_2" evidence="6">
        <location>
            <begin position="11"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="16633" checksum="607FFADD169AEBD1" modified="2008-04-29" version="1">MIELLLKLLNDAIFSAIPAVGFAMVFNVPKRFLPYCAVAGALGHSCRTLLLHVNLPIEWATFVAAALVGLVTIGFAKRHLAPPLMYAVAAIIPMIPGTYAFNTVIALVQLTAQSEISPELTSAVISNGLKTVFILGALSVGLAMPSLLYFRTRPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN5</accession>
    <name>B1KGN5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323709.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1070"/>
    <dbReference type="EnsemblBacteria" id="ACA85363">
        <property type="protein sequence ID" value="ACA85363"/>
        <property type="gene ID" value="Swoo_1070"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1070"/>
    <dbReference type="HOGENOM" id="CLU_1894771_0_0_6"/>
    <dbReference type="OrthoDB" id="2007409at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="15776" checksum="437006DE47DE4FB6" modified="2008-04-29" version="1">METWRNLICKANQSFRAGDWKSAESQYLTAMERIDHLYKNYSDNEQILMAWLASYHNLSELYGRLGRVDAQLSHIMQPYHQLKNRLMTQADHEPIYAAILHGINLSCKELYLYQKQQLEISGGVNLKYQQPVFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGW6</accession>
    <name>B1KGW6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ion-translocating oxidoreductase complex subunit C</fullName>
            <ecNumber evidence="9">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Rnf electron transport complex subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnfC</name>
        <name evidence="13" type="ordered locus">Swoo_2558</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325176.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2558"/>
    <dbReference type="EnsemblBacteria" id="ACA86835">
        <property type="protein sequence ID" value="ACA86835"/>
        <property type="gene ID" value="Swoo_2558"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2558"/>
    <dbReference type="eggNOG" id="COG4656">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010808_2_1_6"/>
    <dbReference type="OMA" id="QQLYWYS"/>
    <dbReference type="OrthoDB" id="688908at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00461">
        <property type="entry name" value="RsxC_RnfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010208">
        <property type="entry name" value="Ion_transpt_RnfC/RsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026902">
        <property type="entry name" value="RnfC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43034">
        <property type="entry name" value="PTHR43034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13375">
        <property type="entry name" value="RnfC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01945">
        <property type="entry name" value="rnfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="375"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="414"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="545"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="636"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="683"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="730"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="450"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="641"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="683"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="784" mass="83492" checksum="5DF0C218A452D8DA" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH16</accession>
    <name>B1KH16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4072</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326657.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4072"/>
    <dbReference type="EnsemblBacteria" id="ACA88328">
        <property type="protein sequence ID" value="ACA88328"/>
        <property type="gene ID" value="Swoo_4072"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4072"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="LIRCMNL"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="237"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="253" mass="27727" checksum="F5E6F39243C3FD47" modified="2008-04-29" version="1">MLSMKSISKVFKTDLVETHALRDFNLEVNEGEFVAVTGPSGSGKTTFLNIAGLLEGFTHGDYFLDGVNISNLSDNKSAAIRNEKIGFIFQGFNLIPDLNLAENVEVPLRYRGFNAAERKRRVQHALEQVGLAARMKHLPSQLSGGQQQRVAIARALAGEPRFLLADEPTGNLDSMMARQVMELLEEINKAGTTIIMVTHDPELARRAQRNIQIVDGQVCDFTMYQGGAEKPHLVSETDSASDGQQAQTEQVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH19</accession>
    <name>B1KH19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326660.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4075"/>
    <dbReference type="EnsemblBacteria" id="ACA88331">
        <property type="protein sequence ID" value="ACA88331"/>
        <property type="gene ID" value="Swoo_4075"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4075"/>
    <dbReference type="eggNOG" id="COG2391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037802_2_1_6"/>
    <dbReference type="OMA" id="WGIAGFC"/>
    <dbReference type="OrthoDB" id="1518604at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="16948" checksum="628AF99C3C819BC7" modified="2008-04-29" version="1" precursor="true">MNNKWIASLSGLLFGAGLLLSGMAEPVKVIGFLDLKGLLDGSWDPSLMLVMAGALSVYIPVFHLYVKPRVKPRACANSTHSSGPVCDSQYHLPEVKKPDGQLIFGAGIFGLGWGIAGICPGPALVNLGSLDISLGLFMISMITGLYIGKLSQNYLGTQAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH39</accession>
    <name>B1KH39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326680.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4095"/>
    <dbReference type="EnsemblBacteria" id="ACA88351">
        <property type="protein sequence ID" value="ACA88351"/>
        <property type="gene ID" value="Swoo_4095"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4095"/>
    <dbReference type="HOGENOM" id="CLU_458480_0_0_6"/>
    <dbReference type="OrthoDB" id="169853at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032774">
        <property type="entry name" value="WG_beta_rep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14903">
        <property type="entry name" value="WG_beta_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="595" mass="67716" checksum="F040D3DA50878EF6" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH41</accession>
    <name>B1KH41_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326682.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4097"/>
    <dbReference type="EnsemblBacteria" id="ACA88353">
        <property type="protein sequence ID" value="ACA88353"/>
        <property type="gene ID" value="Swoo_4097"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4097"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039610_0_0_6"/>
    <dbReference type="OMA" id="ALIYIHI"/>
    <dbReference type="OrthoDB" id="1742337at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="231"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="399" mass="45594" checksum="03D5CF4D2EB8BD3C" modified="2008-04-29" version="1">MESITQVTNTPENHSTTPVRNANIDAIRGLAVLGILFMNIYYFGNAVSGYASHEISPFHDTLVELFSNFFLEGRFISLFAMLFGVGLAVQFNRYSKQNIDAYKQIKSRLKWLLVFGAVHGIVIWSGDVLFAYGLSGFLALCYLKLDNDKLIKKSLLFIAISVFTFTLFSIFSPEERFIRGSELFEEEYLIWFSTYSEQLLMQLFVFITLLFFIPLTLMWFSTGLMLLGVALYRKGIFQQGFSKRHLIWFALASIFFSTLDSLLSFSENPILHTLSGVIVLLSAIPMALIYMHLLIKICQNRSTVLAPLQKVGRLAFSLYILQSICGVLLFRHFEPTLVNTLDRPDYMLIAIGYSILQLILATIYFNYFNQGPLEKLWRGLAKAKPNAAQENDQLLNQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH45</accession>
    <name>B1KH45_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326686.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88357">
        <property type="protein sequence ID" value="ACA88357"/>
        <property type="gene ID" value="Swoo_4101"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4101"/>
    <dbReference type="eggNOG" id="ENOG502Z8DI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_993078_0_0_6"/>
    <dbReference type="OMA" id="QMNLCNI"/>
    <dbReference type="OrthoDB" id="906159at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018883">
        <property type="entry name" value="Delta_CA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10563">
        <property type="entry name" value="CA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="SSF51069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766598" evidence="1">
        <location>
            <begin position="27"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="287" mass="30846" checksum="6F71781B8C377C64" modified="2008-04-29" version="1" precursor="true">MSYKTRVLCATAMLLPFLTTATSAKSADHSVSDQVIEKQRAALAANTKGKGYGPQSPRDIDTIQGNNKRVFAQAPVFSQMNLCNIHFHKNAEHKGGEFTKYAGNGDGHGYHSGYQYSGKLSKAELAPLKHKVGASKHGSLYPGDTIEVHYVHSTAQVSPGATLGACLSDANKNPQLRVETQVYVLVNDAKASNFITLTELGMKNGLNQALNIPSNTGTPVQYTGSTTGPGYNEKASPLQVSWSVRPQVMKVNINSVGKWLESNAFDEDHAHGVRNLVTNPDLLSAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF3</accession>
    <name>B1KHF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">General secretion pathway protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323807.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1168"/>
    <dbReference type="EnsemblBacteria" id="ACA85461">
        <property type="protein sequence ID" value="ACA85461"/>
        <property type="gene ID" value="Swoo_1168"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1168"/>
    <dbReference type="eggNOG" id="ENOG5033B0D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_752046_0_0_6"/>
    <dbReference type="OMA" id="EPIMLGA"/>
    <dbReference type="OrthoDB" id="1515498at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032389">
        <property type="entry name" value="GspB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16537">
        <property type="entry name" value="T2SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="328" mass="35900" checksum="B3ED2ACDC9E86359" modified="2008-04-29" version="1">MSILLDAVTRAKQQNADINLDPVLTPRAQYEQLSRGRNRGVLLLLSLVILSLLVVIVWLVRDQSTEVVKIENQPQQVESVLPEKVQEIAVVDESSASVKNGIQLAGKVALPIAESMPVRYQAQSQPHQPRQVVRESSSRNLTASSVDDTAGEPIILGANANHKGQELLNSLKYQVDSAAHDLGMTKSQVQQQPEQAQNQAQPQVEEETRNYQSEGNLLAAFEAALKEVEVNRSVATPVTEKSLDPIPTPKQDTLPSYGQLPAGLQLQVPEFNINAHVYSSDPNNRWLNVDGAELQQGDSIGGKLEIVEIRPRDVVLAIQGTEFKVPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF4</accession>
    <name>B1KHF4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Citrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_1169</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323808.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1169"/>
    <dbReference type="EnsemblBacteria" id="ACA85462">
        <property type="protein sequence ID" value="ACA85462"/>
        <property type="gene ID" value="Swoo_1169"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1169"/>
    <dbReference type="eggNOG" id="COG1055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029697_0_0_6"/>
    <dbReference type="OMA" id="YFMYRNK"/>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045016">
        <property type="entry name" value="NhaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43269">
        <property type="entry name" value="PTHR43269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="CitMHS" evidence="12">
        <location>
            <begin position="18"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="415" mass="45446" checksum="9F8C5E256A4C6924" modified="2008-04-29" version="1">MLYIFLISLAILALLSIIFEEVTHLNKAKTTLFFGCVSWIALFMSAGDPGHEKLIAAELNENLLEIATLWLFLMSTMTFVAYLNAKGMIQILVQKLFPQKVSVRVLMLQVALFSLILSAICDNVTATLVSLGLLTTFKLDNQMRRRMAVLIIFAVNSGGVSLITGDVTTLMIFLGGHVQMSELLILFVPAAVSVMLLAVLFSLKAEGHVSTTPITREYHKVDIVIAIIFFCTIIATMALNILFGIPPVLTFLTGLSILFLVGHNFRSKKEEMEILEYIRQVEYDTLLFFLGILLLVGMLKEIGTLDLLTEVYAMYDPNISNFVTGIGSAILDNVPLTAALLKAEPVLTTAEWLGLTYSVGVGGSLLVIGSASGIIAMSKVKELTFVSYLKYVPALLLCYSLGYGLTLFIANHLHG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHG7</accession>
    <name>SYD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartate--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="1">AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aspS</name>
        <name type="ordered locus">Swoo_2575</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325192.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHG7"/>
    <dbReference type="SMR" id="B1KHG7"/>
    <dbReference type="STRING" id="392500.Swoo_2575"/>
    <dbReference type="EnsemblBacteria" id="ACA86852">
        <property type="protein sequence ID" value="ACA86852"/>
        <property type="gene ID" value="Swoo_2575"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2575"/>
    <dbReference type="eggNOG" id="COG0173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014330_3_2_6"/>
    <dbReference type="OMA" id="YQLDVEM"/>
    <dbReference type="OrthoDB" id="226836at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000091043" description="Aspartate--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="1">
        <location>
            <begin position="197"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="219"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="483"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="535"/>
            <end position="538"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <sequence length="595" mass="66187" checksum="54136FB5FF9B4AEB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ3</accession>
    <name>B1KHJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325218.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2601"/>
    <dbReference type="EnsemblBacteria" id="ACA86878">
        <property type="protein sequence ID" value="ACA86878"/>
        <property type="gene ID" value="Swoo_2601"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2601"/>
    <dbReference type="eggNOG" id="ENOG5032YUN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063619_2_1_6"/>
    <dbReference type="OMA" id="TVLWFAK"/>
    <dbReference type="OrthoDB" id="1968186at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021457">
        <property type="entry name" value="DUF3108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11306">
        <property type="entry name" value="DUF3108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767355" evidence="1">
        <location>
            <begin position="23"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="255" mass="29313" checksum="B5FC4A64D73A91D0" modified="2008-04-29" version="1" precursor="true">MSVSKRLIVAAHLLSASFTLAAAPTPLTPQTAEYQVNYGNIELGKARYQLPVAEDNVYQYRFDSDVSLLVLSDRRNVRSEFTLDGDQLTPMRYTHNRKGTGPSFQEQTAFAKGQSVVHSRYKDERAKLPYTEVLYDPLMAQLQFRLDMVKGKKELHYAMVKEGEIDEYDFRVVGKERMNIDSGSYETIKIEVVRDSKKRQTFFWMAPDLAYLPVRLTHFEKGSKQLDIKLLSYRFSEPQQDLTSVSSKPQPTTHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHM9</accession>
    <name>B1KHM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2637</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325254.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2637"/>
    <dbReference type="EnsemblBacteria" id="ACA86914">
        <property type="protein sequence ID" value="ACA86914"/>
        <property type="gene ID" value="Swoo_2637"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2637"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_6"/>
    <dbReference type="OMA" id="LDKYATH"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="23181" checksum="308C421F89D79F4C" modified="2008-04-29" version="1">MTRAQILLVDDHPTLRQGLAQLISLEDNLDVIAQAGSGDEAISLAIKHAPDLILLDLNMKGLSGIDTLIALKRAEIDSKIVIFTVSDSESDVLQAIKFNTDGYLLKDSEPEELIEKINLAIQGEFVISAPLTKILARSLRPESKASSPLENLTQRELQNLKLIASGKSNKDIANTLGIAETTVKVHVKNLLKKLGLKSRVEAAVWAVEHKIGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ2</accession>
    <name>B1KHQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2661</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325277.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2661"/>
    <dbReference type="EnsemblBacteria" id="ACA86937">
        <property type="protein sequence ID" value="ACA86937"/>
        <property type="gene ID" value="Swoo_2661"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2661"/>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_543904_0_0_6"/>
    <dbReference type="OrthoDB" id="1007123at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="541" mass="62006" checksum="CBF65F6CC0EB8A55" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT2</accession>
    <name>B1KHT2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326739.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88410">
        <property type="protein sequence ID" value="ACA88410"/>
        <property type="gene ID" value="Swoo_4154"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4154"/>
    <dbReference type="eggNOG" id="ENOG50341J0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2059819_0_0_6"/>
    <dbReference type="OMA" id="CPHAGFF"/>
    <dbReference type="OrthoDB" id="1830918at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="13175" checksum="77CCC0E7D6470D56" modified="2008-04-29" version="1">MTEVDKALLIELLDYPRKRIVQSMELKFCPHAGFFNTSDEQCLNCHQGMECVWMNHNDELVAVEEKSVAELKQQLLIAVDFIDSSLTPHHLSRRNCGCENCVWLRKTQKVLAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT5</accession>
    <name>B1KHT5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CutA1 divalent ion tolerance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326742.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4157"/>
    <dbReference type="EnsemblBacteria" id="ACA88413">
        <property type="protein sequence ID" value="ACA88413"/>
        <property type="gene ID" value="Swoo_4157"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4157"/>
    <dbReference type="eggNOG" id="COG1324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098807_2_0_6"/>
    <dbReference type="OMA" id="VYTTFPD"/>
    <dbReference type="OrthoDB" id="1801957at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419">
        <property type="entry name" value="PTHR23419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="107" mass="12077" checksum="EFB0CEF3A8DC99EF" modified="2008-04-29" version="1">MQDEFLLVMTSCPTSELATKIAQVLVGSKLAACIQVSAPVTSIYEWQGEICEETEFNLQIKCLALNYSEIETQIKQLHPYEVPEIIAVPISHGLPDYLKWIHDVSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV4</accession>
    <name>B1KHV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88432">
        <property type="protein sequence ID" value="ACA88432"/>
        <property type="gene ID" value="Swoo_4176"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4176"/>
    <dbReference type="HOGENOM" id="CLU_3029929_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="55" mass="6034" checksum="303DC2C9D96538E9" modified="2008-04-29" version="1" precursor="true">MKLFTLAILALSLLLISLPLQSNILIQALLLICIILVALGIYKALIQLDSDKDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV5</accession>
    <name>B1KHV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88433">
        <property type="protein sequence ID" value="ACA88433"/>
        <property type="gene ID" value="Swoo_4177"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4177"/>
    <dbReference type="eggNOG" id="COG1633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145213_0_0_6"/>
    <dbReference type="OMA" id="VHSSIRM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="19808" checksum="9519C104E4D60C5B" modified="2008-04-29" version="1">MNPLINLAKAFGEYLGEDIMRFQQLRELLGYVATCRHEMSQLYGRLLSDADSSRVKMMLEYFKQHQQAVAEQLEDYIDEAPKKVLDTWYKDITFEDFIKRCHELTLTANMSEEDILEAHLDLDNRLIDLLQKTAEHSSSSEISGALNDLVRVEKIQQQRLVHSSIRMDDL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY8</accession>
    <name>RS18_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsR</name>
        <name type="ordered locus">Swoo_4210</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005497284.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHY8"/>
    <dbReference type="SMR" id="B1KHY8"/>
    <dbReference type="STRING" id="392500.Swoo_4210"/>
    <dbReference type="EnsemblBacteria" id="ACA88466">
        <property type="protein sequence ID" value="ACA88466"/>
        <property type="gene ID" value="Swoo_4210"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4210"/>
    <dbReference type="eggNOG" id="COG0238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148710_2_3_6"/>
    <dbReference type="OMA" id="QKKYCRF"/>
    <dbReference type="OrthoDB" id="1940575at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000114451" description="30S ribosomal protein S18">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <sequence length="75" mass="8902" checksum="B716277204C773B8" modified="2008-04-29" version="1">MARYFRRRKFCRFTAEGVTEIDYKDIVTLKNYITESGKIVPSRITGTNAKYQRQLARAIKRARYLSLLPYTDLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI12</accession>
    <name>B1KI12_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1197</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323836.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1197"/>
    <dbReference type="EnsemblBacteria" id="ACA85490">
        <property type="protein sequence ID" value="ACA85490"/>
        <property type="gene ID" value="Swoo_1197"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1197"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_6"/>
    <dbReference type="OMA" id="GMKYVTM"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="18"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="487" mass="52767" checksum="ACED8489BEE6C372" modified="2008-04-29" version="1">MSLVVYPNYIHGKALHNESGETFEVINPANGKVNYLVEVADEKIQQAAIESAKEGFKTWSKMTAMERSRVLLNAVALLRERNDELAAIEVQDTGKPWQEASVVDVVTGADSIEFFAGLAPSIEGNQQSVGDDFYYTRREPLGICAGIGAWNYPLQIACWKSAPALACGNVMIFKPSEETPLGALKLAEIFTQAGVPDGVFNVVQGDGRVGAWLTNHDEIAKVSFTGEVGTGKKVMAAAATSLKEVTMELGGKSPLIIFNDADIDNAVSAAMLGNFYTQGEICTNGTRVFVQQDIYPKFIEKLLKRTQENIVCGDPMDPETNFGALISKEHQNKVLNYIEIGKSEGAELLAGGHALTPNNCPGGYFVAPTIFGQCSDEMTLSREEVFGPVMSVLPFNDEDEVIRRANDTRLGLAAGVFTQDITRAHRVIHQMQAGICWINAYGASPAEMPVGGYKMSGIGRENGSETLKAYTQIKAVYVGMQPLESPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI58</accession>
    <name>B1KI58_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ordered locus">Swoo_1244</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323882.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1244"/>
    <dbReference type="EnsemblBacteria" id="ACA85536">
        <property type="protein sequence ID" value="ACA85536"/>
        <property type="gene ID" value="Swoo_1244"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1244"/>
    <dbReference type="eggNOG" id="COG1159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038009_1_2_6"/>
    <dbReference type="OMA" id="WAEVDVI"/>
    <dbReference type="OrthoDB" id="984717at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="34"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="235"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="68"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="89"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="153"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="183"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="89"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="153"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="329" mass="37425" checksum="1F9C7A90641B1905" modified="2008-04-29" version="1">MSKKDSNSKSEPSLDDLLAQMNNPSSAAKYDVTYCGMVAIVGRPNVGKSTLLNNLLGQKISITSKKPQTTRHRIMGIHTDAERQVVFIDTPGLHIEEKRAINRLMNRAAASSLAEVSLVIFVVDGMTWTDDDEMVLRKLQSRDDGRKTVLAVNKVDNIKDKEELFPYLEELSKKFPFDEILPISATKGTNVQRILDMSVESVPESPHFFPEDYVTDRSQKFMASEIVREKLMRFLGDELPYDCTVEIEQFKMMENGVYQINALVLVERETQKRMVIGNKGERIKKISSAARMDMEVLFDNKVFLEMWVKVKSGWADDERALRSLGYGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIG4</accession>
    <name>B1KIG4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease T</fullName>
            <ecNumber evidence="4">3.1.13.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Exoribonuclease T</fullName>
            <shortName evidence="4">RNase T</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rnt</name>
        <name evidence="6" type="ordered locus">Swoo_2739</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase T family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2739"/>
    <dbReference type="EnsemblBacteria" id="ACA87015">
        <property type="protein sequence ID" value="ACA87015"/>
        <property type="gene ID" value="Swoo_2739"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2739"/>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082724_0_0_6"/>
    <dbReference type="OMA" id="CYMVNHL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016896">
        <property type="term" value="F:exoribonuclease activity, producing 5'-phosphomonoesters"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06134">
        <property type="entry name" value="RNaseT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00157">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005987">
        <property type="entry name" value="RNase_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30231:SF2">
        <property type="entry name" value="PTHR30231:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01298">
        <property type="entry name" value="RNaseT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="20"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="24345" checksum="B22D5B449330404E" modified="2008-04-29" version="1">MLMSDICDANKLSHRFRGYFPVVIDVETAGFNAQTDALLEIAVTMLKMDDEGILSLDKTLHFHIEPFEGANLEPEALAFTGIDPTNPLRGAVSEKEAFLEIFKEVKKAQKAAGCHRSIIVAHNAAFDHGFVSQAIERCALKRTPFHPFATFDTAALSGLALGHTVLAKACAIAGIPFDNSEAHSALYDTERTAELFCLIVNRWKALGGWPIAIDEESKEEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIH4</accession>
    <name>B1KIH4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase (Glutamine-hydrolyzing)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2749</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325361.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2749"/>
    <dbReference type="EnsemblBacteria" id="ACA87025">
        <property type="protein sequence ID" value="ACA87025"/>
        <property type="gene ID" value="Swoo_2749"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2749"/>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014658_2_2_6"/>
    <dbReference type="OMA" id="DWSGIYS"/>
    <dbReference type="OrthoDB" id="610569at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="350"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="557" mass="62620" checksum="F8669CB291C67CD2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIL8</accession>
    <name>B1KIL8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RarD protein, DMT superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4258</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88514">
        <property type="protein sequence ID" value="ACA88514"/>
        <property type="gene ID" value="Swoo_4258"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4258"/>
    <dbReference type="eggNOG" id="COG2962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054508_0_0_6"/>
    <dbReference type="OMA" id="LMQYIEP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="28"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="327" mass="36037" checksum="4AD868A12C2B0F68" modified="2008-04-29" version="1">MRASKQSNLLKLPSMHSTTEKQASSSFKGNALAAFSFLLWGLMPLYYQYLPNADINELLAFRILFSVPFMALVFLLLGRTMPSMSALKADKRSVALCGLASLIMCVSWYSFTWAITHGQVLAASLGFFINPLFAIGLGVLFLGDKLTSAQKLAVVLGTCGISYMVYSYGELPWLALSMGSFFALYGLCKKFIRFDSLTSVTLEAIWLMPFAAIYLIWLWSSDQSVAISSALSGEVSVLLLYMGTAPLTLLPLVFFALAVRATSLSMIGLMQYIEPSLHFLLAVILFNEHFDQVKAVSFALIWTGLLLCSLEALPTLRHKLLANRHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIL9</accession>
    <name>B1KIL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PGAP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326842.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4259"/>
    <dbReference type="ESTHER" id="shewm-b1kil9">
        <property type="family name" value="Lipase_2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88515">
        <property type="protein sequence ID" value="ACA88515"/>
        <property type="gene ID" value="Swoo_4259"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4259"/>
    <dbReference type="eggNOG" id="COG1075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029537_5_0_6"/>
    <dbReference type="OMA" id="IWTPYDL"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="194" mass="21948" checksum="E3A34F49BDFF69F4" modified="2008-04-29" version="1">MKIVLVHGIFNTGRVMSRMQKSFEAEGYECFAPTLAPFDGSLGIEHASTSLKQQIELRFGEHEMITLVGFSMGGIVARYYLQALGGAKRVANLFTLSSPHHGTYTAYLPYPSKTFKQLRPNSKLLRFLQENEETLEGVNLFSYWTAIDYTIVPSSSSLWPWAKNKRFFIFLHLSVIFSRKITDEIIAELRGAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIT9</accession>
    <name>B1KIT9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus modification protein PilV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1295"/>
    <dbReference type="EnsemblBacteria" id="ACA85587">
        <property type="protein sequence ID" value="ACA85587"/>
        <property type="gene ID" value="Swoo_1295"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1295"/>
    <dbReference type="eggNOG" id="COG4967">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103234_0_1_6"/>
    <dbReference type="OMA" id="QAVGAMI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013362">
        <property type="entry name" value="Pilus_4_PilV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02523">
        <property type="entry name" value="type_IV_pilV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="20232" checksum="372C3F23FB4EE041" modified="2008-04-29" version="1">MNNGTKGFSLIEVLVSLVILVIGLIGIFNLHIVSKRSSFESFQQTQASYYVNDIINRMKLNRSQLINYNGTYSGGLSQPGTSCDVAAGGPAVVCTNVETRLWDLYQWEQLFGGASEQLSGRDVGGLDTPTACIRTQANGQVLVVMTWRGIRALSDGTANAAGDNAAFIKGCGSSSDRRRVYSINTVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ43</accession>
    <name>B1KJ43_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2787</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325399.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2787"/>
    <dbReference type="EnsemblBacteria" id="ACA87063">
        <property type="protein sequence ID" value="ACA87063"/>
        <property type="gene ID" value="Swoo_2787"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2787"/>
    <dbReference type="eggNOG" id="COG3083">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030247_1_0_6"/>
    <dbReference type="OMA" id="QMLFSRW"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012159">
        <property type="entry name" value="YejM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024588">
        <property type="entry name" value="YejM_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11893">
        <property type="entry name" value="DUF3413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004950">
        <property type="entry name" value="Mmb_sulf_HI0842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3413" evidence="3">
        <location>
            <begin position="9"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="254"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="595" mass="67441" checksum="32ED57F715FF244D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ94</accession>
    <name>B1KJ94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326893.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4313"/>
    <dbReference type="EnsemblBacteria" id="ACA88566">
        <property type="protein sequence ID" value="ACA88566"/>
        <property type="gene ID" value="Swoo_4313"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4313"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="FHRIVET"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="314" mass="35521" checksum="DC22CD1384714BA0" modified="2008-04-29" version="1">MKTEDIALFHRIVETGSLVEAADLLNLPKSTVSRRLQILEDDLNIKLFHRQSRSMTLTASGSHFYDKTLSILGDLEQTLVELTDTEAEIDGHLRILIFPVPELLDIANGIFDFMDHNPELTVELIVSTEPQDMIRNNIDLAFMVEDSFNENEMVAREMITEELHFVASPDYLAKAGTPVLPEDLAKHNSILFRYPNGRIFNEVPFGNDMKIAVKGNLCLNSIQLCLEASLTGRGIAFLPIELTRDHVERGELTMLFEDVEPYVGKCYLVYPSRRFISLASQRFIDHMMSALESCNAGKGCGREERLRGSIKSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJB3</accession>
    <name>B1KJB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4332</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326911.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4332"/>
    <dbReference type="EnsemblBacteria" id="ACA88585">
        <property type="protein sequence ID" value="ACA88585"/>
        <property type="gene ID" value="Swoo_4332"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4332"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096130_0_0_6"/>
    <dbReference type="OMA" id="IIGCFYV"/>
    <dbReference type="OrthoDB" id="1780140at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="265" mass="28614" checksum="2453EEA0BABF8CC2" modified="2008-04-29" version="1" precursor="true">MFDTDLLSILFPAFVAGILVLSTHVVLGQQVLKRGIIFIDLAIAQVAALGAIVAHLNHDIEHLPYSHVWMPALFALAGAGFIAWLSKRMADELEAIIGCFYVLAAVGAMLLLSNDPHGAEMLKQLMSGQILWVNWSQLILPASVSACILLLISIKPALLDGRGFYIMFALVITLSVELVGVYLVFSTLILPALAVNKYHARFKLPAAYAVGLVGYISGLVLSASFDLPSGAAIVATLAISTILFRLVLGRKAQPQKRDQEKLIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJB5</accession>
    <name>B1KJB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326913.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4334"/>
    <dbReference type="EnsemblBacteria" id="ACA88587">
        <property type="protein sequence ID" value="ACA88587"/>
        <property type="gene ID" value="Swoo_4334"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4334"/>
    <dbReference type="eggNOG" id="COG3746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038901_0_0_6"/>
    <dbReference type="OMA" id="NYKYQHL"/>
    <dbReference type="OrthoDB" id="958173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767121" evidence="2">
        <location>
            <begin position="25"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="403" mass="45291" checksum="0EBE8736DD80483D" modified="2008-04-29" version="1" precursor="true">MRVTNFRVSHVAAACALISTSAFAENPTLTNPAISAVLDGYYQNTERPMAERVEGFGLGHTELALSANVDDMFYGKLTAVVEIHEGETELGIEEAFIQTLAMPGGFSIRAGRFLSDVGYLNNQHVHTDAFSDRPAAYRAFLGSHYFDDGVRFNYVAPTDLYWAMGVEAFKGDSMRAADEHNEREYEELGVYTAYTKFGGDIGANGSWQAGLSYMRNENGRMTAAEEHDGHEEEESEHDHGHEHSHSAQYTGENTYIADFVYKWAPNGNYKYQHLTLSGEYFKVTDFTPLEEHGHDEPDHEHEVGQGVDDQQGWYLSGVYQFSPNWSAGLRYGEVETQEMHGDHFHAQKLKETEASLAWHHSHFSTVRLQYTNQKGTNFDGIEDDNVITLQYVMTLGAHGAHQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJC8</accession>
    <name>B1KJC8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326926.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4347"/>
    <dbReference type="EnsemblBacteria" id="ACA88600">
        <property type="protein sequence ID" value="ACA88600"/>
        <property type="gene ID" value="Swoo_4347"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4347"/>
    <dbReference type="eggNOG" id="ENOG5031EAF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2289756_0_0_6"/>
    <dbReference type="OMA" id="CETMTNE"/>
    <dbReference type="OrthoDB" id="1983334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="101" mass="11704" checksum="43603BFFED3C7272" modified="2008-04-29" version="1" precursor="true">MKTAQMSLLTLVIFLVLGITLYLISPANQKEQPESWSSFVYTQGYESGRYKKLDDFNDYASCRAYSIETSEKFEQAPWECGLRCRFDSSRQGFQCEAMKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG7</accession>
    <name>B1KJG7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326965.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4387"/>
    <dbReference type="EnsemblBacteria" id="ACA88639">
        <property type="protein sequence ID" value="ACA88639"/>
        <property type="gene ID" value="Swoo_4387"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4387"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_3_1_6"/>
    <dbReference type="OMA" id="WAYYSIR"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="13213" checksum="6602FBFEFA897D81" modified="2008-04-29" version="1">MTALDLFKALSDETRLRSLLLIKAEQELCVCELMQALEESQPKVSRHLAQLRKAGLLLDKRQGQWVFYRINPSLPIWALKVVEETFLANGELIESNLTRLKQMGDRPDRVKSCCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJX6</accession>
    <name>B1KJX6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4878 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2888"/>
    <dbReference type="EnsemblBacteria" id="ACA87163">
        <property type="protein sequence ID" value="ACA87163"/>
        <property type="gene ID" value="Swoo_2888"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2888"/>
    <dbReference type="eggNOG" id="ENOG502ZCGV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144715_0_0_6"/>
    <dbReference type="OMA" id="ESTPEYT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024267">
        <property type="entry name" value="DUF4878"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12870">
        <property type="entry name" value="DUF4878"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4878" evidence="1">
        <location>
            <begin position="12"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14944" checksum="89356D3F4A377444" modified="2008-04-29" version="1">MGCEPEVSDKGPALTPEQVSVGFFNAIYNDKDIKKAQEYVNEPMKEVIAHYHIASAVQRHMLNLSMTDVKLEIAEIDIDFFRKFTDDVTVIVKMHGLKGGSRWIDDRTIRLQKNGGRWEIVEILPEKGNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJY3</accession>
    <name>B1KJY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2897</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325506.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2897"/>
    <dbReference type="EnsemblBacteria" id="ACA87170">
        <property type="protein sequence ID" value="ACA87170"/>
        <property type="gene ID" value="Swoo_2897"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2897"/>
    <dbReference type="eggNOG" id="COG4181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="YSLFPWR"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="26486" checksum="349464DD933E607D" modified="2008-04-29" version="1">MSEISAITVKALVKSVATQEGELTILNGINMDVKQGQSIAILGPSGSGKSTLLGLLAALDSPSSGEIILDGVALHSLNEEKKAALRKQKVSFIFQSFMLVDTLNALENVMLPAELAGINNAKEKAQSMLERVGLSHRLTHFPNQLSGGEQQRVAIARAFICEPKVLFADEPTGNLDAANSQKVADMLFELNRESDTTLVLVTHDLALAKRCERQLLMNSGELSEDSEMETQKRAHKPVSLHSVGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF9</accession>
    <name>B1KKF9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidyl-Lys metalloendopeptidase</fullName>
            <ecNumber evidence="9">3.4.24.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1511</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.4.24.20" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324145.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1511"/>
    <dbReference type="MEROPS" id="M35.003"/>
    <dbReference type="EnsemblBacteria" id="ACA85799">
        <property type="protein sequence ID" value="ACA85799"/>
        <property type="gene ID" value="Swoo_1511"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1511"/>
    <dbReference type="eggNOG" id="COG4104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041257_0_0_6"/>
    <dbReference type="OMA" id="RYNTWFG"/>
    <dbReference type="OrthoDB" id="1316225at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11306">
        <property type="entry name" value="M35_peptidyl-Lys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029463">
        <property type="entry name" value="Lys_MEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034115">
        <property type="entry name" value="M35_peptidyl-Lys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14521">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01351">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765002" evidence="7">
        <location>
            <begin position="24"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Aspzincin_M35" evidence="8">
        <location>
            <begin position="222"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="360" mass="39052" checksum="B9113A0D4B00682E" modified="2008-04-29" version="1" precursor="true">MNTKKALSAIAVTAALISSSAYADGINATLEMSQQDYKSSDNVVVKVTLTNEEHIPVKVLKWYTAADGVEEALFKVTANGEERAYLGAHYKRQAPTKNDYIKLKSGESISYDVELSSLYDMSSTAEYEISYDVSSLQLFAPNPGQAKKLARLGVEGIHSQPTSFYLEGRELKQGTKKGKPGGGDGGGEVDGVTFTGRCSNSQKTDILAGLDAAKGMSADANQHLNGNNSSSTRYNTWFGNYSSSRWNTVSNNFSKIDSALNNEPLTIDCSCKKRYFAYVYPTQPYKIYMCRAFWSAPTTGTDSKGGTIIHEMSHFNVVAGTDDIVYGQSGAKALAISDPAQAIQNADSHEYFAENTPNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG9</accession>
    <name>B1KKG9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclase/dehydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribosome association toxin RatA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324155.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1521"/>
    <dbReference type="EnsemblBacteria" id="ACA85809">
        <property type="protein sequence ID" value="ACA85809"/>
        <property type="gene ID" value="Swoo_1521"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1521"/>
    <dbReference type="eggNOG" id="COG2867">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079653_3_1_6"/>
    <dbReference type="OMA" id="YIDGPFK"/>
    <dbReference type="OrthoDB" id="1691158at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="PTHR12901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="3">
        <location>
            <begin position="13"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16203" checksum="73AA7CBBFC2C9264" modified="2008-04-29" version="1">MPQISRSVLVRFSAMQMYEIVNDVESYKEFLPGCVGGKVLEFDGSTMLASVDVSKAGISKTFTTRNQIVPGKSIQLALENGPFKHLIGEWRFTELTEDACKIDFELNFEFSSSLVDMAFGKIFNDLMTSMVTAFTGRAKVIYSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI3</accession>
    <name>B1KKI3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CbiA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324169.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1535"/>
    <dbReference type="EnsemblBacteria" id="ACA85823">
        <property type="protein sequence ID" value="ACA85823"/>
        <property type="gene ID" value="Swoo_1535"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1535"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037612_5_4_6"/>
    <dbReference type="OMA" id="NESVFLM"/>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="247" mass="27267" checksum="F395763CF12946D0" modified="2008-04-29" version="1">MIILVGGEKGGSGKSCIAQNIAVFLTAECNASVIMVDCDPQRTTSDWIQARNNNPELASINCVQLYGKIRNDLLSLEQHYDFVIVDCGGQDNLALRASMSVASHVLMPLRPKRRDLKTVNHMDDIVATCMMINPKMKASFVITQCPSLPSQANRILEAKEVCRTYDINVLDAINYSRNIFDDSEESGLSVIEIEPKGKAAKEMRSIACEMLEAADATEIRNRIAAAKMNNTRGDYGTSRSQEKLYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP9</accession>
    <name>B1KKP9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AhpC-TSA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325602.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2995"/>
    <dbReference type="EnsemblBacteria" id="ACA87266">
        <property type="protein sequence ID" value="ACA87266"/>
        <property type="gene ID" value="Swoo_2995"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2995"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110678_0_0_6"/>
    <dbReference type="OMA" id="MPRTVWI"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767445" description="AhpC-TSA domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="AhpC-TSA" evidence="2">
        <location>
            <begin position="30"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="159" mass="18470" checksum="D5DEB01FC36CF845" modified="2008-04-29" version="1" precursor="true">MKRLQQRVLLLFFCAIFSTHYAHATSLALNKSQLASIKQQNMGKRWLMLLWSVDCPPCFKELTTVQQLKQKYPQINVVLVNTDANDEAIVEHLEIIQEYQLTDLTNFHFAVDQGDQSRFLIDPHWYGELPRSYFVTNNGEFHGKSGVISQSILARWLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW2</accession>
    <name>B1KKW2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4517</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327094.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88768">
        <property type="protein sequence ID" value="ACA88768"/>
        <property type="gene ID" value="Swoo_4517"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4517"/>
    <dbReference type="eggNOG" id="ENOG5033T3C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_417317_0_0_6"/>
    <dbReference type="OMA" id="HINHQKF"/>
    <dbReference type="OrthoDB" id="227793at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767166" evidence="2">
        <location>
            <begin position="22"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="642" mass="68760" checksum="C417895D1247C02E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL35</accession>
    <name>B1KL35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase family 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0075"/>
    <dbReference type="CAZy" id="GT25">
        <property type="family name" value="Glycosyltransferase Family 25"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84376">
        <property type="protein sequence ID" value="ACA84376"/>
        <property type="gene ID" value="Swoo_0075"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0075"/>
    <dbReference type="eggNOG" id="COG3306">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071269_3_0_6"/>
    <dbReference type="OMA" id="RRYGEWW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="26120" checksum="D49DCFA4661A1C87" modified="2008-04-29" version="1">MTKQCEPLGITPERVSAVRGSLLSEKEKSDVYQLSANLSKYDKILNDGEIGCYMSHIRCWEQIVEQELDFALVLEDDAILTDNIIKYVEKLAPSSADWDYIKLSHGSKVKSAVDSMDLGDGLTLRKELKLPSTTTGQLISLSGAKKLLAHAYPITRPIDMDIQYWFEKSLRCFVVAPFPILNGDFGSEINKTDDRRFVKKRPIRRVLQKLRYEILLLCSRHKLPDFPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL57</accession>
    <name>B1KL57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322747.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0097"/>
    <dbReference type="EnsemblBacteria" id="ACA84398">
        <property type="protein sequence ID" value="ACA84398"/>
        <property type="gene ID" value="Swoo_0097"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0097"/>
    <dbReference type="eggNOG" id="ENOG503355Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1486792_0_0_6"/>
    <dbReference type="OMA" id="HSMFLMT"/>
    <dbReference type="OrthoDB" id="2026676at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="19455" checksum="9B340A21C5275778" modified="2008-04-29" version="1">MGKVLNFSLQDALFIGFCATLLVALKSMLRLKLGITGHSMFLMTFFYLICYGVVGRVGCITACGLLSGLVAMMLSIGKGGPLILIKFGLPALAMDLSMLLFSGLLTLKLRCIVVGLVGCFAWAAKSWVENLLVGMTIQVALVQFMLSMLKGGVFTILAALMVPSVLSRLKAHDLLFNEDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA2</accession>
    <name>B1KLA2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322792.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0142"/>
    <dbReference type="EnsemblBacteria" id="ACA84443">
        <property type="protein sequence ID" value="ACA84443"/>
        <property type="gene ID" value="Swoo_0142"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0142"/>
    <dbReference type="eggNOG" id="COG4994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119560_2_0_6"/>
    <dbReference type="OMA" id="QMRFHQG"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
        <location>
            <begin position="11"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="123" mass="14322" checksum="02109BA7E8B7EFC7" modified="2008-04-29" version="1">MQTGLEQQLIELELYLLKSEVRSSVEELASLIHDDFLEFGGSGIRFGKEEVLMRLPKERCPEFCATDFELRVLTPDLAQLLYRASMIKPDEFITRYSLRSSLWKRSGDNWQMIFHQGTPCEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA8</accession>
    <name>B1KLA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322798.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0148"/>
    <dbReference type="EnsemblBacteria" id="ACA84449">
        <property type="protein sequence ID" value="ACA84449"/>
        <property type="gene ID" value="Swoo_0148"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0148"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="LWWSQRA"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="320"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="377"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="651" mass="72616" checksum="6B8E696B754CBBC6" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE3</accession>
    <name>B1KLE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acylneuraminate-9-phosphate synthase</fullName>
            <ecNumber evidence="2">2.5.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.57" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324214.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1582"/>
    <dbReference type="EnsemblBacteria" id="ACA85868">
        <property type="protein sequence ID" value="ACA85868"/>
        <property type="gene ID" value="Swoo_1582"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1582"/>
    <dbReference type="eggNOG" id="COG2089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040465_0_0_6"/>
    <dbReference type="OMA" id="YRHRVEF"/>
    <dbReference type="OrthoDB" id="674753at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047444">
        <property type="term" value="F:N-acylneuraminate-9-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006190">
        <property type="entry name" value="AFP_Neu5c_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020007">
        <property type="entry name" value="N-AcNeuraminate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="Neu5Ac_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03569">
        <property type="entry name" value="NeuB_NnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50844">
        <property type="entry name" value="AFP_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AFP-like" evidence="1">
        <location>
            <begin position="307"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="38845" checksum="0757787DDAE0C3B0" modified="2008-04-29" version="1" precursor="true">MSKTFVIAEAGVNHNGDENLAIELINVAHKAGADAVKFQTFNAKSLVTATAKQADYQISNTKKVESQLTMLSRLELSHDAHQRLINYCNKLGIQFLSTAFDSESLYFLVHTLQLKTLKIASGEITNAPFILEHARTGCDLILSTGMSTLAEIESALGVIAFGLTTSNDSTPSIEAFTAAYMSLEGQKALKEKVSLLHCTTEYPAPFNEINLKAMDTLASVFSLQVGYSDHSQGITIPIAAAARGASIIEKHFTLDNEMSGPDHKASLEPDELTAMVTAIRTVEAAMGDGVKTPQVSELKNINVARKSLVTVNPIRKGDIFSTENLAVKRPGTGASPYLYWQRLGTKADKDYAIGEVIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK6</accession>
    <name>B1KLK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3032</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325639.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3032"/>
    <dbReference type="EnsemblBacteria" id="ACA87303">
        <property type="protein sequence ID" value="ACA87303"/>
        <property type="gene ID" value="Swoo_3032"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3032"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024570_3_1_6"/>
    <dbReference type="OMA" id="GWLFCLP"/>
    <dbReference type="OrthoDB" id="539510at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="89"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="399"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="493"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="575"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="650" mass="72280" checksum="FF156D597286B30B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLU9</accession>
    <name>B1KLU9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transf_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327154.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4579"/>
    <dbReference type="EnsemblBacteria" id="ACA88829">
        <property type="protein sequence ID" value="ACA88829"/>
        <property type="gene ID" value="Swoo_4579"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4579"/>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077108_0_0_6"/>
    <dbReference type="OMA" id="PVSMNFW"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="13"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="319" mass="34858" checksum="923EBDE9DAAEF1AD" modified="2008-04-29" version="1">MTTDCENEALTLVIMAAGLGSRFGGDKQLAALGPNDETMLELAIVSACRAGFSGVVLVIRPELESDIEALFNDSLNDKLDAGFSHDFCYQAMDDLPEVALAHLSDVNHREKPWGTAHALWSARKKVKGRMAVINADDYYGDTAFELLASGLNESKEDWMLVAYPLSLTLSEHGGVNRGVCLVKEGLLQSVAEWTDIRQSSDEGLVGTSKGERGVLSPSVPVSMTCWGFTQDIFLAIEAELIQFISVYGQEAKSECFLPDVVQHSMSKAALINNLPDAKRVRVKTAQEPWFGVTYPQDAVWVRQKLSKLLNNKSNGVISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLY1</accession>
    <name>B1KLY1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-(Acyl-carrier-protein) reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327186.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4611"/>
    <dbReference type="EnsemblBacteria" id="ACA88861">
        <property type="protein sequence ID" value="ACA88861"/>
        <property type="gene ID" value="Swoo_4611"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4611"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_6"/>
    <dbReference type="OMA" id="GFCNTEQ"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011285">
        <property type="entry name" value="FabG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01831">
        <property type="entry name" value="fabG_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="241" mass="25836" checksum="6EEA77B72E57526C" modified="2008-04-29" version="1">MNKRVLITGSSRGIGKAIALQLAEAGFDIALHFHSNKVAAEQTREELNSLGVKVSFLQFDIADREGVKAAIDSDIAQYGAYYGVVLNAGINCDTAFPAMTEDEWDSVVHTNLDGFYNVIHPTVMPMIQTRTGGRIITMASVSGIAGNRGQVNYSASKAGIIGATKALSLELAKRKITVNCIAPGLIETDMVADIPKDMVKELVPMRRMGKPSEIAGLAKFLMSEDAAYITRQVISVNGGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMA4</accession>
    <name>B1KMA4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PaaX family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0216"/>
    <dbReference type="EnsemblBacteria" id="ACA84517">
        <property type="protein sequence ID" value="ACA84517"/>
        <property type="gene ID" value="Swoo_0216"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0216"/>
    <dbReference type="eggNOG" id="COG3327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067515_2_0_6"/>
    <dbReference type="OMA" id="LLIHEYR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012906">
        <property type="entry name" value="PaaX-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013225">
        <property type="entry name" value="PaaX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011965">
        <property type="entry name" value="PaaX_trns_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07848">
        <property type="entry name" value="PaaX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08223">
        <property type="entry name" value="PaaX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020623">
        <property type="entry name" value="PaaX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PaaX" evidence="1">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PaaX_C" evidence="2">
        <location>
            <begin position="185"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="35588" checksum="7A802154D68C47ED" modified="2008-04-29" version="1">MASEDNYLKFINQRVEKSSSGPSMLVTLFGDLVSQHGNWIWLGSLITGLKPFGYSERLIRTSVFRLVKSDWLITKKVGRRTYYALSETAKAHHDKAARRIYSSEPSSLADAWTVVIPIFVPDNVKETFKKQLQWLGFSPLTNGAYAHLEVDKQSLEDTLLELGLKDAVIVLSCKVDGSHSKNVFKRLVKEYWGLETLEASYKEFLDAYRPLIIKFNKGKMPSDETCFLLRILLIHEYRRILLKDKQLPEDMLPNGWVGFEAHELVGKLYAQLAQASVNYAVENLENAQGHLPYVSAKFWQRFLLNKLSVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMD7</accession>
    <name>B1KMD7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/peptide transporter</fullName>
            <ecNumber evidence="7">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1649</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324281.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1649"/>
    <dbReference type="EnsemblBacteria" id="ACA85935">
        <property type="protein sequence ID" value="ACA85935"/>
        <property type="gene ID" value="Swoo_1649"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1649"/>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_0_2_6"/>
    <dbReference type="OMA" id="ATKFFEA"/>
    <dbReference type="OrthoDB" id="470322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="490" mass="53134" checksum="1B52C4BF05E9C420" modified="2008-04-29" version="1">MSVAKPQGTMLGHPKGLFLLFTTELWERFSYYAMRAILVLYLVDSVQSQGGHGLGWTSADALSLYGTFTGLVYLTPLIGGWLADTYLGQRRAIIIGGALMAAGQFILGTPHAWVPGMETEVFYLGLGVLILGNGLFKPNISTMVGDLYEEGDHRRDGAFTIFYMGINVGAFLSGIIVGSVVAYFDGNFQAGFICAGIGMVLSLIIQFMFAQKLLGDIGRRPAAQLEKEKAAEKGEVRKEPLTKVERDRIKVIMIMGLFTIIFWAGFEQAGGLMNLFTNDFTDRSIGSWEVPTTWFQSLNAMFIVIFAPVVASIWIRLGKNEPNSPVKFALGLVLLGIGFLFMIGAVLEMGGDANAKSSMWWLVGAYFFHTMGELCLSPIGLSMVTKLAPLRIASLMMGAWFLFVAAANKIGGVVGSFIGHGGPKEEQLANAMSIFAGIAITAAASGILLYFMADKLVDWMHGAEDGPVHTEEEALEEEMAVTAEHEGIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMD9</accession>
    <name>B1KMD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polysaccharide export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324283.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1651"/>
    <dbReference type="EnsemblBacteria" id="ACA85937">
        <property type="protein sequence ID" value="ACA85937"/>
        <property type="gene ID" value="Swoo_1651"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1651"/>
    <dbReference type="eggNOG" id="COG1596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011447_0_1_6"/>
    <dbReference type="OMA" id="VMGEVQH"/>
    <dbReference type="OrthoDB" id="687725at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010425">
        <property type="entry name" value="Caps_synth_GfcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06251">
        <property type="entry name" value="Caps_synth_GfcC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766838" evidence="2">
        <location>
            <begin position="26"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="4">
        <location>
            <begin position="212"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="4">
        <location>
            <begin position="295"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="4">
        <location>
            <begin position="585"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Caps_synth_GfcC" evidence="3">
        <location>
            <begin position="697"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="915" mass="100571" checksum="4E30BFECAC8C0B3E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMK6</accession>
    <name>B1KMK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Maleylacetoacetate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1719"/>
    <dbReference type="EnsemblBacteria" id="ACA86004">
        <property type="protein sequence ID" value="ACA86004"/>
        <property type="gene ID" value="Swoo_1719"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1719"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_20_1_6"/>
    <dbReference type="OMA" id="VYNAHRF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03191">
        <property type="entry name" value="GST_C_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03042">
        <property type="entry name" value="GST_N_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034330">
        <property type="entry name" value="GST_Zeta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034333">
        <property type="entry name" value="GST_Zeta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="95"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="24960" checksum="41341474E4AE91C8" modified="2008-04-29" version="1">MMKLYGYWRSSAAYRVRIALNHKGLEAEQLSVHLVKDGGEQHKADYARLNPQELVPAFIDTDAEGNEDEFILSQSLAIIEYLDEKYPEVKLVPDSMYDRALVRSMAMSIACEVHPLNNLKVLQYLAKGLNLDDDAKSAWYHHWIHEGFAALEKQLIKYSGRYCFGDSVTLVDLCLVPQVYNANRFKVGLEAYPNIVRITQNCNQLDAFIDASPENQADAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP0</accession>
    <name>B1KMP0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chorismate mutase</fullName>
            <ecNumber evidence="2">5.4.99.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325754.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3147"/>
    <dbReference type="EnsemblBacteria" id="ACA87418">
        <property type="protein sequence ID" value="ACA87418"/>
        <property type="gene ID" value="Swoo_3147"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3147"/>
    <dbReference type="eggNOG" id="COG1605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118625_0_0_6"/>
    <dbReference type="OMA" id="MADWLAT"/>
    <dbReference type="OrthoDB" id="1872101at2"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008240">
        <property type="entry name" value="Chorismate_mutase_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01806">
        <property type="entry name" value="CM_mono2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767214" description="Chorismate mutase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate mutase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="185" mass="21253" checksum="2BED46CB2130A710" modified="2008-04-29" version="1" precursor="true">MIKVIRCCLLIIFSFHANAENDASMLFNTINERLSYMEDVALFKAVNHLPIEDSPREKRVIASAQISAATQGLDSALIKDFFKAQIDVAKAIQYRYRADLLSQPRLDTPKDLRLEIRPHLIRLGDSLIVQLSNYIKKHGQIQANEFETFNSSIEHRYISDADKLRLFNALMQVDYLNKPDSNKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN08</accession>
    <name>B1KN08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327283.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4715"/>
    <dbReference type="EnsemblBacteria" id="ACA88965">
        <property type="protein sequence ID" value="ACA88965"/>
        <property type="gene ID" value="Swoo_4715"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4715"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029603_0_0_6"/>
    <dbReference type="OMA" id="ICFGFNP"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="429" mass="47227" checksum="5AFF9BA80CBD7B60" modified="2008-04-29" version="1">MLFSRRFFPYFVTQCLGALNDNVYKNVLLLMVAYASVDQLPMSINLFVNIAAAVFILPFLLFSAHAGSLADVKDKAWLIRRIKLVELVLMSFAALAIFSQSYLAMLFLLFLMGTQSAYFGPVKYALLPQTLKPEELVRGNAWVEVSTFLAILCGTVGAGVLVSSDQGVGISAGLVVLFAAIGVLASWNIPDLPADIDADKQPRKGNWQTLKWAFQQRDIWAAITGISWFWFLGASYLTQFPNFTRLFLFSDPSVVSVLLALFSVGIAAGSFISVRLSKGKVELGIVPLGLCGLTLFGIDFVLAIPAGVESLYQASSFVMSAEHYRLMFDLFMIGVSGGVYIVPLYSFIQSKAKASERAQVIAANNILNALFMITSAILAIVVLQLLTWDIPTLFMILASSNLLVLLFICLRNEVFRQSACHFWVKKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN26</accession>
    <name>B1KN26_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
            <shortName evidence="3">T2SS protein E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Type II traffic warden ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4733</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4733"/>
    <dbReference type="EnsemblBacteria" id="ACA88983">
        <property type="protein sequence ID" value="ACA88983"/>
        <property type="gene ID" value="Swoo_4733"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4733"/>
    <dbReference type="eggNOG" id="COG2804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013446_2_0_6"/>
    <dbReference type="OMA" id="LIRKPHG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013369">
        <property type="entry name" value="T2SS_GspE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02533">
        <property type="entry name" value="type_II_gspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T2SP_E" evidence="4">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="523" mass="58152" checksum="5B2C43A32B21B7AB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN93</accession>
    <name>B1KN93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0289</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322939.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0289"/>
    <dbReference type="EnsemblBacteria" id="ACA84590">
        <property type="protein sequence ID" value="ACA84590"/>
        <property type="gene ID" value="Swoo_0289"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0289"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="DNVWGYQ"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="14"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="138"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="243" mass="27607" checksum="81A34FEA5C9BDFA7" modified="2008-04-29" version="1">MNGTRTANNQYTHKILLVEDEPDLANLVKLNLNTLNFDVIHCTTLKQANQNLELKSFDLILIDRTLPDGDGLMLCQQLRHAGKETPCMMLTAKDSEADIVLGLESGADDYLTKPFSVLELRARVKALLRRGHQTEHEEQQLDFNGITINCDTREVIAFDTQLELTAREFDLLLFMAKHPKQVFSRLQLLEAVWGYSYSGYEHTVNSHINRLRAKLSHCTPAAELVKTVWGVGYKFSPPETRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE2</accession>
    <name>B1KNE2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1734</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324365.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1734"/>
    <dbReference type="EnsemblBacteria" id="ACA86019">
        <property type="protein sequence ID" value="ACA86019"/>
        <property type="gene ID" value="Swoo_1734"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1734"/>
    <dbReference type="eggNOG" id="COG4665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_1_0_6"/>
    <dbReference type="OMA" id="LWIPQGL"/>
    <dbReference type="OrthoDB" id="2073326at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23339" checksum="D27B2EACC7A0DEBB" modified="2008-04-29" version="1">MNLDTNKNNLNPITRLLDSMIVRVEAISQWMAIGGGVLILFSVFLIFSEVVLRKLFNVSIGGADELSGYALGISITWALAYNVIKRVNVRIDAVYQMLTPRYASFVNVMSLISLGLIGILLVYYAGLTTLDTWEFSSRANTPLGTPLIIPQFLWLMGFVLFETTISLLLIRSLIAIFSGDDVKVNTLCGVRTVEDEIMAENLDLDKPRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNH2</accession>
    <name>B1KNH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Two component transcriptional regulator, LytTR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1765"/>
    <dbReference type="EnsemblBacteria" id="ACA86049">
        <property type="protein sequence ID" value="ACA86049"/>
        <property type="gene ID" value="Swoo_1765"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1765"/>
    <dbReference type="eggNOG" id="COG3279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_14_1_6"/>
    <dbReference type="OMA" id="IQAFEEH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="26413" checksum="15D396A4E7F8A026" modified="2008-04-29" version="1">MIVDDELFAREELLDLLSEHQDIDIVGQCSNAIEALQMISKHKPQLLFLDIQMPKITGMELIGMLDPDTMPYVVFVTAFDEYAIKAFDNHAFDYLLKPIDEERLSQTLKRIRKDLSPKPVEVLAPKILTHLPCYTGTRLKVLPLSEVEYIFSDLSGIHIATSKELVHTHLTLKVLEEKTSLVRCHRQYLIKPDAVSEIEVQESGAEVITLSGAKVPVSRRYLKPLKQLFGFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL0</accession>
    <name>B1KNL0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">topA</name>
        <name evidence="13" type="ordered locus">Swoo_1803</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1803"/>
    <dbReference type="EnsemblBacteria" id="ACA86087">
        <property type="protein sequence ID" value="ACA86087"/>
        <property type="gene ID" value="Swoo_1803"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1803"/>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_4_3_6"/>
    <dbReference type="OMA" id="PECKYTR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013263">
        <property type="entry name" value="TopoI_Znr_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08272">
        <property type="entry name" value="Topo_Zn_Ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="12">
        <location>
            <begin position="19"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="216"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="887"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="892"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="906" mass="100833" checksum="740396C8D27258AF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNR8</accession>
    <name>B1KNR8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325862.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3256"/>
    <dbReference type="EnsemblBacteria" id="ACA87526">
        <property type="protein sequence ID" value="ACA87526"/>
        <property type="gene ID" value="Swoo_3256"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3256"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_3_6"/>
    <dbReference type="OMA" id="VQTYYMA"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="32426" checksum="DED4F51FCDA3541F" modified="2008-04-29" version="1">MRLRHIEIFHAIYTTGSITNAAKILHVSQPSVSKVLSHAELQLGFQLFNRVKGRLTPTEEAKILFGDVDKIYQQLRSIKNTANNIKKSEFGSIKIGLTPALGFDSIPEAVANFHRDHPAVSIQLQTIHNESVMHTLLERKCDLAIVFSPDKQPGLNEIELARSELTIVYPKALFPHCPTKLSFAELSEHEFIDIGDSGPLGDLLWTRMLEENINITPNIRVQTYFLAARIVAQNIGLCVVDKLTALGNLSPNTAMASFDPPLEFSISALHLENSNLSSANKEFLNYLTSVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNR9</accession>
    <name>B1KNR9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3257</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3257"/>
    <dbReference type="EnsemblBacteria" id="ACA87527">
        <property type="protein sequence ID" value="ACA87527"/>
        <property type="gene ID" value="Swoo_3257"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3257"/>
    <dbReference type="eggNOG" id="COG3367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059741_1_0_6"/>
    <dbReference type="OMA" id="LTVGTDM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035402">
        <property type="entry name" value="DUF1611-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035086">
        <property type="entry name" value="DUF1611_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011669">
        <property type="entry name" value="UCP026760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40690">
        <property type="entry name" value="PTHR40690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07755">
        <property type="entry name" value="DUF1611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17396">
        <property type="entry name" value="DUF1611_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026760">
        <property type="entry name" value="UCP026760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1611_N" evidence="3">
        <location>
            <begin position="40"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1611" evidence="2">
        <location>
            <begin position="131"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="38242" checksum="7B3F4A18757BBCD7" modified="2008-04-29" version="1">MIKAPYLLFIGDATDKLSIKMAQGPVDWSPDQCLGELSVTGCTVTTGLPQLSIEQAAKMGAKSFVLGFANSGGVLDAKWHDVIKQALEQGLDVVSGLHQKLADIDDLAQLASNLGRQLIDIRHPQQSFKTGTGEKRSGKRLLTVGTDCSVGKMYTSLALEKEMKAQQLDVDFRATGQCGILIKGKGVAIDCVISDFISGATESLSPDNKDEHWDIIEGQGSLSHPAFAGVSLGLLHGSQPDAIVICHALNRSHMRGLPNSQFPSIADTINLNLQAARLTNPNVYIAGIAINTSSVSIKKGQEICRAIGQKFGLACVDPLRDGVTSIVSHLQLPPPKITATNDSSLKNHGEKITDMAKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ7</accession>
    <name>B1KNZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4779"/>
    <dbReference type="EnsemblBacteria" id="ACA89028">
        <property type="protein sequence ID" value="ACA89028"/>
        <property type="gene ID" value="Swoo_4779"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4779"/>
    <dbReference type="eggNOG" id="ENOG50339IW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_186874_3_1_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021677">
        <property type="entry name" value="DUF2986"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11661">
        <property type="entry name" value="DUF2986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="49" mass="5508" checksum="6B1B10EC0253F573" modified="2008-04-29" version="1">MNRKKKINETLKGKAKKANAKLHSSNKPKYISKAERARIAEAEKDGLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPK9</accession>
    <name>B1KPK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1878</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1878"/>
    <dbReference type="EnsemblBacteria" id="ACA86162">
        <property type="protein sequence ID" value="ACA86162"/>
        <property type="gene ID" value="Swoo_1878"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1878"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034273_0_0_6"/>
    <dbReference type="OMA" id="QRQHLYY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="579"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="297"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="599" mass="67932" checksum="D002B930FA14ACAD" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ0</accession>
    <name>B1KPQ0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_3314</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325919.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3314"/>
    <dbReference type="EnsemblBacteria" id="ACA87583">
        <property type="protein sequence ID" value="ACA87583"/>
        <property type="gene ID" value="Swoo_3314"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3314"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003654_0_0_6"/>
    <dbReference type="OMA" id="TENAMAG"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="16" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="14">
        <location>
            <begin position="502"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="13">
        <location>
            <begin position="555"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="14">
        <location>
            <begin position="637"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="14">
        <location>
            <begin position="776"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="847"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="1086"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="1233"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="15">
        <location>
            <begin position="1393"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1467"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1137"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1282"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="7">
        <location>
            <position position="1432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA87583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1582" mass="176724" checksum="A36BBDF075FD518C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPR9</accession>
    <name>B1KPR9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325938.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87602">
        <property type="protein sequence ID" value="ACA87602"/>
        <property type="gene ID" value="Swoo_3333"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3333"/>
    <dbReference type="eggNOG" id="ENOG502ZUU6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1299032_0_0_6"/>
    <dbReference type="OMA" id="CFRELFS"/>
    <dbReference type="OrthoDB" id="1347080at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="195" mass="22070" checksum="CF0E4A9AF527F063" modified="2008-04-29" version="1">MDFSTDEVALFQELFSSTSTELVGESNKVLDIQTQIPSSLASILHQSSLSLLAEGQGYKLWIPLKIEKDEFGGLRPNFGTPEVIDINGHERSWRVKQPEDVTLTDETNNQLGDILSLSSTGLTLRIQDPKALKQGIDGKVLYLNLPDQKHVELQLEPVRSDRHVFAARFECLNHDQDVIREFLFSLHKSRNEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPY4</accession>
    <name>B1KPY4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4848</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327414.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4848"/>
    <dbReference type="EnsemblBacteria" id="ACA89097">
        <property type="protein sequence ID" value="ACA89097"/>
        <property type="gene ID" value="Swoo_4848"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4848"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_0_6"/>
    <dbReference type="OMA" id="GIMNITF"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="27"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="317"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA89097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="413" mass="45064" checksum="AEDF964C71006333" modified="2008-04-29" version="1">MLNRVFHSAYEGTVAAIESIFAHSFRSALTTLGIIIGVAAVITVVSIMEGLSQGVGNQLKDLGSDMVTIKAHTNTELEMLGVTNQLTYDDYLLIKSKVPGIKEIAAKMRAFSFGSEARFGQYSTHTQVIGTESDYQNVVNIFPLEGRFLSNTDDIKRRRVVFVGSSVLKKLNLPQHPVGEFILLGGEWFKVIGVAETRGSLFGFDQDNYIIAPFSTIRSLNGSDRTNNIDIVFRPEAGVDLTLLNERVRNLLRSKYRLTEQDQDFFEFETAERTRKQFSDITDSITYVAAGVVGISLIVGGIGIMNIMLVSVTERTKEIGIAKALGATSRIILTQFLVEASVLALFGGIVGILLGYLLAGVVFMFMPVIGSLSVPTWAIWLALGFSGTIGVVFGIAPAIKASKLDPIDALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC1</accession>
    <name>B1KQC1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane adhesin like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0478</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323125.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0478"/>
    <dbReference type="EnsemblBacteria" id="ACA84776">
        <property type="protein sequence ID" value="ACA84776"/>
        <property type="gene ID" value="Swoo_0478"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0478"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_225671_0_0_6"/>
    <dbReference type="OMA" id="WSVQGTA"/>
    <dbReference type="OrthoDB" id="413616at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040853">
        <property type="entry name" value="RapA2_cadherin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010221">
        <property type="entry name" value="VCBS_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17803">
        <property type="entry name" value="Cadherin_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01965">
        <property type="entry name" value="VCBS_repeat"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="4">
        <location>
            <begin position="660"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="2837"/>
            <end position="3023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="3259" mass="343313" checksum="9D93236AC136873B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ3</accession>
    <name>B1KQJ3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1948</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324578.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1948"/>
    <dbReference type="EnsemblBacteria" id="ACA86232">
        <property type="protein sequence ID" value="ACA86232"/>
        <property type="gene ID" value="Swoo_1948"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1948"/>
    <dbReference type="eggNOG" id="COG1047">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098197_1_0_6"/>
    <dbReference type="OMA" id="KVWKPGM"/>
    <dbReference type="OrthoDB" id="2044224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="17681" checksum="0360F59B1EFDD112" modified="2008-04-29" version="1">MSIKNDMVVQFNYTLRDEQGEVLETNEGLDPIAYLHGHDNMMPGVEDAIAGKTVGEKFSVTLAPETTYGVRNEEAIQRVSVKHLQGEKVWKAGMRALINTDQGQRQVTIIKMGKFMATVDVNHPLAGRELTFDLEIIDARAASDEEIAHGHAHGKGGHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQK0</accession>
    <name>B1KQK0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1955</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1955"/>
    <dbReference type="EnsemblBacteria" id="ACA86239">
        <property type="protein sequence ID" value="ACA86239"/>
        <property type="gene ID" value="Swoo_1955"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1955"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_1_2_6"/>
    <dbReference type="OMA" id="CFGTSGP"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="50"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="242"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="440"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="618" mass="68027" checksum="98558C22CB8AEA0B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR26</accession>
    <name>B1KR26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BRCT domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323191.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0547"/>
    <dbReference type="EnsemblBacteria" id="ACA84843">
        <property type="protein sequence ID" value="ACA84843"/>
        <property type="gene ID" value="Swoo_0547"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0547"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1314693_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="134"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="23677" checksum="90B4B7968FE60DB5" modified="2008-04-29" version="1">MSDNKFNIYVKPSDSDAKESLLAFINAVQSKNFQSLSNASEYCEVEHHLDVELSSSELDGVFNLKFWAVGSLTVEDFLAFLIEELNVSAVEAAVFIGDCGEYDFHFMSSEDDESFDEYDDHEWSWLENPVIEWEDQNIVLTGKFENYESRDELAEELEDLGANIRSSISKKTTLLVTGLRVGPSKLEKAKSLGVRIITENELMESMELC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR61</accession>
    <name>B1KR61_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Spondin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323226.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0582"/>
    <dbReference type="EnsemblBacteria" id="ACA84878">
        <property type="protein sequence ID" value="ACA84878"/>
        <property type="gene ID" value="Swoo_0582"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0582"/>
    <dbReference type="eggNOG" id="ENOG502ZFV4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097554_0_0_6"/>
    <dbReference type="OMA" id="HYHESTA"/>
    <dbReference type="OrthoDB" id="1396644at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009465">
        <property type="entry name" value="Spondin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038678">
        <property type="entry name" value="Spondin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06468">
        <property type="entry name" value="Spond_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spondin" evidence="1">
        <location>
            <begin position="69"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="249" mass="27029" checksum="512BF99A33B054AE" modified="2008-04-29" version="1">MSLVQDVDIKSDVNPIHYHESTAMRHTIKLSLMLFALCLSPNLFADNYGNYHREAVYEVTVTNLTKGIAFTPILAATHKSGMQLFTLGEPSSENIANIAEGGDISGLKDELDSSSRVANTTSTDGLLTNGQSVTFEISSSRRFSQLSLISMLLPTNDTMVALRAKKLPRKRGQTVHYNMRAYDAGSEANDELCVNIPGPVCGGNPFSAPDASDEGYSYPSPGIHGEADLAQSLYDWNGAVAKVKIKRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR87</accession>
    <name>B1KR87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323252.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0608"/>
    <dbReference type="EnsemblBacteria" id="ACA84904">
        <property type="protein sequence ID" value="ACA84904"/>
        <property type="gene ID" value="Swoo_0608"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0608"/>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005379_4_2_6"/>
    <dbReference type="OMA" id="NGPDAIF"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="71"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="423" mass="47012" checksum="CAB67B78A02AA7B4" modified="2008-04-29" version="1">MNNKEIYLSFRDQIFEALDAQMIANMPRDELSRQIQSAVEVLANNFSQPISTAVRTMTVKNLVDELLGLGPLQPLLEDDSINDIMVNGPDQIFYERHGKIHSSEVVFVNEAQLLEIAQRIAARVGRRVDESSPMVDARLSNGSRVNIVIKPIAIDGTTISIRKFREQKIGLEELVGFGSLSPEMARVLMIAARCRLNILISGGTGSGKTTLLNALSNYIADDERIITIEDAAELNLQQPHVVRLETRPASIENSGQVDQRDLIINSLRMRPDRIILGECRGAEAFEMLQAMNTGHDGSMSTLHANTPRDAISRVESMVMMASLNQPLDAIRRTIVGAVHLVVQVNRQRDGSRKITSISEVVGLEGENVVMEELFKFQPTEGQSMEKVLGEYLSPGIMQRSVLMQRAAYFGLQDELMLAFRGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRB3</accession>
    <name>B1KRB3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">7-methyl-GTP pyrophosphatase</fullName>
            <shortName evidence="3">m(7)GTP pyrophosphatase</shortName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(7)-methyl-GTP = diphosphate + H(+) + N(7)-methyl-GMP</text>
            <dbReference type="Rhea" id="RHEA:58744"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58285"/>
            <dbReference type="ChEBI" id="CHEBI:87133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Maf family. YceF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324666.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2036"/>
    <dbReference type="EnsemblBacteria" id="ACA86320">
        <property type="protein sequence ID" value="ACA86320"/>
        <property type="gene ID" value="Swoo_2036"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2036"/>
    <dbReference type="eggNOG" id="COG0424">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040416_1_0_6"/>
    <dbReference type="OMA" id="CAGSFKA"/>
    <dbReference type="OrthoDB" id="1469203at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="199" mass="21817" checksum="3C4A666A21EB05B3" modified="2008-04-29" version="1">MSSRLILASTSPFRQQLLTKLNIPFDTCSPDIDETPKEGEAPDALVMRLAQSKAIKGASGHSQGLMIGSDQVAVIDGRIVGKPLTHEKAVEQLTQASNQIITFYTGLSLHNISTGLSDTRIETFKVHFRELTQAQIEYYLQTEQPYFCAGSFKCEGLGIALFTQLEGKDPNTLVGLPLITLIDMLSKQGYQVLSKNLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF3</accession>
    <name>B1KRF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2076</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324705.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2076"/>
    <dbReference type="EnsemblBacteria" id="ACA86360">
        <property type="protein sequence ID" value="ACA86360"/>
        <property type="gene ID" value="Swoo_2076"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2076"/>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_0_6"/>
    <dbReference type="OMA" id="WESNLSV"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="16"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="426" mass="47732" checksum="F5B2724D6C829395" modified="2008-04-29" version="1">MNSDVSLSRFRQFPRLMWIFLFGSFITRGSYYMVWPFLAVILYERFALSATQVGLILSSAAIISVFTSFIGSSLSDRIGRHQLMYLTGILYIISFSLLAEVDTVSGYVVVMTLCSIATSLWRPLTSAAIGDIITDPKTRELAMQSLYFIVNVGCAVGPLLGVWLGLTGEQSSFYITAVAFALLLVLLYWGFKDHARDKSETESSDSQKAQHTDVKKTKAPVVTRKIMMTILLEDKLLQCLILANVLCMFIYAQMDSSLIQYLTRSEAPNLLELISAMIFTNALVIISTQFLLLKIMARHSLIKRIQFGLVLLIISQVWLAMNPIDLFWGWIGAVIVMSLAETILFPTMNVHIDRLAPDHLRGAYFGAASFYEFGFAFAPLGGGIILDHFGGYWLFMTGAALSLFVIYLYGILERLPRPDFEQIKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRJ4</accession>
    <name>B1KRJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326093.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3494"/>
    <dbReference type="EnsemblBacteria" id="ACA87759">
        <property type="protein sequence ID" value="ACA87759"/>
        <property type="gene ID" value="Swoo_3494"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3494"/>
    <dbReference type="eggNOG" id="ENOG5031I7U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2234746_0_0_6"/>
    <dbReference type="OrthoDB" id="1969247at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="12006" checksum="55B7FED2FCA9E399" modified="2008-04-29" version="1">MVIMDKLLETLESINSDELDKLLDQRDEDPFDSAWINLNQKVSKINVSIDNKDLFIKLSSATNHHEVCSYIADDLELINKAETLGIESEFLGYLKQCYEQGEVPN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRQ8</accession>
    <name>TRUB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="1">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="1">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">truB</name>
        <name type="ordered locus">Swoo_3559</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326156.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRQ8"/>
    <dbReference type="SMR" id="B1KRQ8"/>
    <dbReference type="STRING" id="392500.Swoo_3559"/>
    <dbReference type="EnsemblBacteria" id="ACA87823">
        <property type="protein sequence ID" value="ACA87823"/>
        <property type="gene ID" value="Swoo_3559"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3559"/>
    <dbReference type="eggNOG" id="COG0130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_0_3_6"/>
    <dbReference type="OMA" id="ELQFIRW"/>
    <dbReference type="OrthoDB" id="1166299at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015240">
        <property type="entry name" value="tRNA_sdUridine_synth_fam1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09157">
        <property type="entry name" value="TruB-C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000149832" description="tRNA pseudouridine synthase B">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <sequence length="317" mass="35168" checksum="3502A63FCEF786FF" modified="2008-04-29" version="1">MARRSRGRFIDGIVLLDKDTGMSSNFALQRVKRLFNANKAGHTGALDPLATGMLPICLGEATKFSQHLLDADKRYTVTAKLGERTDTSDSDGEVVQTRPINFTQELLMESLEHFRGETMQVPSMYSALKHEGQPLYKYAREGIEVPRKARPINVFELNFISLEGDELTLDIHCSKGTYIRTITDDLGEMLGCGAHVIMLRRTQVAGYPYERMVSLEQLNEMVSQAEADGVEAKSVLDPLLLPMDTAVSKFREINLAESQAPYLMNGNPVHASGLVADEIVRITIGEEHKFVGIGAMNDDGMLAPKRLIVIREDEVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRT3</accession>
    <name>B1KRT3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326181.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87848">
        <property type="protein sequence ID" value="ACA87848"/>
        <property type="gene ID" value="Swoo_3584"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3584"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064680_1_0_6"/>
    <dbReference type="OMA" id="ALNYTWP"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="8"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="156"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="33502" checksum="A7CA3873EA7AA342" modified="2008-04-29" version="1">MKQSNQAYVYGVGAICLWSTVATAFKLALAHFSPLQLVLVAVTTSIIALGLILVVQGKLSLIKAQFKARPFFYLQTGLINPFLYYLVLFKAYDLLPAQQALSLNYTWAILLPLLSVPMLAQRLRKSDMVAAIIAYFGVFVIATNGNLTSFTFESGTGVMLALTSTLLWSLYWIINTKDKGDPVVSLLLSFLVGFPFILGTLLLTQELPSWDLKAVAAGIYVGLFEMGVTFVLWLVALKKADRTASISTMAFMSPVMSIGFIAWILQEEIAHSTYIGLGLILSALALQQLLPLLNKLKIKSGTSHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRT4</accession>
    <name>B1KRT4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326182.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87849">
        <property type="protein sequence ID" value="ACA87849"/>
        <property type="gene ID" value="Swoo_3585"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3585"/>
    <dbReference type="eggNOG" id="ENOG50306RB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107574_0_0_6"/>
    <dbReference type="OMA" id="RQAYYNE"/>
    <dbReference type="OrthoDB" id="1725718at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767333" evidence="1">
        <location>
            <begin position="34"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="221" mass="24355" checksum="989BC4746E196C1F" modified="2008-04-29" version="1" precursor="true">MTMLIKKITTATLSSLMVISAAFSTLAITPVQAEADRSLSQTYGYDGQQVLLDMDVGSAEVFATDDKEIRVEVLVSQSDSSWFSFWDSVDLADVELDVDQASKRITLKLNDQDDLKQEWKIYLPREAAVNLNVGVGQVEVNNMESDVDIDLGVGHAQIKHSIIYHSVSLESGVGEVSVEDDGRALAIDRNFVRQAYYNEDNTGFGELSVNVGVGQIEVEHY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCW7</accession>
    <name>SMG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein Smg homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">smg</name>
        <name type="ordered locus">Swoo_0041</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Smg family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322691.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCW7"/>
    <dbReference type="STRING" id="392500.Swoo_0041"/>
    <dbReference type="EnsemblBacteria" id="ACA84342">
        <property type="protein sequence ID" value="ACA84342"/>
        <property type="gene ID" value="Swoo_0041"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0041"/>
    <dbReference type="eggNOG" id="COG2922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133242_0_0_6"/>
    <dbReference type="OMA" id="IHNETEM"/>
    <dbReference type="OrthoDB" id="1747288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00598">
        <property type="entry name" value="Smg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007456">
        <property type="entry name" value="Smg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38692">
        <property type="entry name" value="PTHR38692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04361">
        <property type="entry name" value="DUF494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000129906" description="Protein Smg homolog">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00598"/>
        </source>
    </evidence>
    <sequence length="157" mass="18522" checksum="EC8A52BB03F7AAB2" modified="2008-04-29" version="1">MFDILMYLFENYVHSEVEFLVDEDELTQELTRAGFHQSEIIKALSWLENLAELQEGDKPYLCNHAQHSFRIYTQDEMDKLDVECRGFILFLEQIEVLNVVTREMVIDRIMELDESALILEDLKWVVLMVLFNAPGNESAYEQMEDLIFEQPDGRLHS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCY7</accession>
    <name>TUSA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfur carrier protein TusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tusA</name>
        <name type="ordered locus">Swoo_0017</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Sulfur carrier protein which probably makes part of a sulfur-relay system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfur carrier protein TusA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322667.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCY7"/>
    <dbReference type="SMR" id="B1KCY7"/>
    <dbReference type="STRING" id="392500.Swoo_0017"/>
    <dbReference type="EnsemblBacteria" id="ACA84318">
        <property type="protein sequence ID" value="ACA84318"/>
        <property type="gene ID" value="Swoo_0017"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0017"/>
    <dbReference type="eggNOG" id="COG0425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165255_5_0_6"/>
    <dbReference type="OMA" id="FCQFLGH"/>
    <dbReference type="OrthoDB" id="2042068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097163">
        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03423">
        <property type="entry name" value="SirA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00413">
        <property type="entry name" value="Thiourid_synth_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022931">
        <property type="entry name" value="Sulphur_carrier_TusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01148">
        <property type="entry name" value="UPF0033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000199933" description="Sulfur carrier protein TusA">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="1">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00413"/>
        </source>
    </evidence>
    <sequence length="81" mass="9186" checksum="92554AF1AC620D21" modified="2008-04-29" version="1">MSNQFSEAQHQLDALGLRCPEPVMMVRKSVRKMAQGETLLIIADDPATTRDIPSFCEFMDHKLLASQTETTPYQYLIQKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD31</accession>
    <name>B1KD31_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase M17 leucyl aminopeptidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3602</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326199.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3602"/>
    <dbReference type="EnsemblBacteria" id="ACA87866">
        <property type="protein sequence ID" value="ACA87866"/>
        <property type="gene ID" value="Swoo_3602"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3602"/>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013734_0_1_6"/>
    <dbReference type="OMA" id="GEHPAMP"/>
    <dbReference type="OrthoDB" id="631014at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="6">
        <location>
            <begin position="340"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="512" mass="54133" checksum="6EAE96DD5A524FC2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD85</accession>
    <name>B1KD85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3658</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326253.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3658"/>
    <dbReference type="EnsemblBacteria" id="ACA87920">
        <property type="protein sequence ID" value="ACA87920"/>
        <property type="gene ID" value="Swoo_3658"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3658"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="ETSAMYL"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766469" evidence="5">
        <location>
            <begin position="27"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="63"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="401"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="894" mass="99074" checksum="227C23073866E652" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA8</accession>
    <name>B1KDA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323257.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0613"/>
    <dbReference type="EnsemblBacteria" id="ACA84909">
        <property type="protein sequence ID" value="ACA84909"/>
        <property type="gene ID" value="Swoo_0613"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0613"/>
    <dbReference type="eggNOG" id="ENOG50337KF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095582_2_0_6"/>
    <dbReference type="OMA" id="DICGRAD"/>
    <dbReference type="OrthoDB" id="1913682at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031582">
        <property type="entry name" value="TadF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16964">
        <property type="entry name" value="TadF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19575" checksum="554BF4C86A522454" modified="2008-04-29" version="1" precursor="true">MKSKQHGAFTIELAFVLLFTSALLVFTGDIAFQLLNRVNLDRVNYSLVNVLKERTRFFDENLIVTSAEVDELDILAARLLGYGQTSENAPYGIRVEWIVNDRYSSIDKGIEGGAPCIPGDSLKDRGHLAPQTSADKRFPLYQVTLCLNTDSWFNQFWGDDAQHYIHSSSVMPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDE2</accession>
    <name>B1KDE2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0647</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323290.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0647"/>
    <dbReference type="EnsemblBacteria" id="ACA84943">
        <property type="protein sequence ID" value="ACA84943"/>
        <property type="gene ID" value="Swoo_0647"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0647"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008655_0_0_6"/>
    <dbReference type="OMA" id="GMNNTGQ"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07473">
        <property type="entry name" value="Peptidases_S8_Subtilisin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034204">
        <property type="entry name" value="PfSUB1-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764304" evidence="6">
        <location>
            <begin position="21"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="8">
        <location>
            <begin position="546"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="673"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="836" mass="86444" checksum="7E7AA88E0E6EFFC6" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDE8</accession>
    <name>B1KDE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323296.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0653"/>
    <dbReference type="EnsemblBacteria" id="ACA84949">
        <property type="protein sequence ID" value="ACA84949"/>
        <property type="gene ID" value="Swoo_0653"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0653"/>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005126_12_0_6"/>
    <dbReference type="OMA" id="EDKGDMQ"/>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0050">Antiport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="7">
        <location>
            <begin position="389"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="544" mass="59525" checksum="A92A91770661D9B2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-26" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDK2</accession>
    <name>Y2115_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcgL domain-containing protein Swoo_2115</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_2115</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324744.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDK2"/>
    <dbReference type="SMR" id="B1KDK2"/>
    <dbReference type="STRING" id="392500.Swoo_2115"/>
    <dbReference type="EnsemblBacteria" id="ACA86399">
        <property type="protein sequence ID" value="ACA86399"/>
        <property type="gene ID" value="Swoo_2115"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2115"/>
    <dbReference type="eggNOG" id="COG3100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155118_1_0_6"/>
    <dbReference type="OMA" id="MICAVYK"/>
    <dbReference type="OrthoDB" id="2016633at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.510.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01866">
        <property type="entry name" value="UPF0745"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038068">
        <property type="entry name" value="YcgL-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027354">
        <property type="entry name" value="YcgL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38109">
        <property type="entry name" value="PTHR38109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05166">
        <property type="entry name" value="YcgL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160191">
        <property type="entry name" value="SSF160191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51648">
        <property type="entry name" value="YCGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000375381" description="YcgL domain-containing protein Swoo_2115">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="YcgL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01866"/>
        </source>
    </evidence>
    <sequence length="93" mass="10914" checksum="9D79B627D28FB418" modified="2008-04-29" version="1">MICAVYKSRRKADSYLFVEKRNEFERVPEALLEMFGPPELVMMLPLMKRDHLGFADIEKVKSELADKGFYLQLPPPVVNLLEEHKREIGYSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE21</accession>
    <name>B1KE21_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Methyl-accepting chemotaxis sensory transducer with Cache sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_0712</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323354.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0712"/>
    <dbReference type="EnsemblBacteria" id="ACA85007">
        <property type="protein sequence ID" value="ACA85007"/>
        <property type="gene ID" value="Swoo_0712"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0712"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_19_6"/>
    <dbReference type="OMA" id="MTASHAN"/>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="12">
        <location>
            <begin position="296"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="355"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="542"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="627" mass="68694" checksum="2B17E146B5967148" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE28</accession>
    <name>B1KE28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ion transport 2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_0719</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323361.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0719"/>
    <dbReference type="EnsemblBacteria" id="ACA85014">
        <property type="protein sequence ID" value="ACA85014"/>
        <property type="gene ID" value="Swoo_0719"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0719"/>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011722_6_1_6"/>
    <dbReference type="OMA" id="ANIAAWF"/>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="13">
        <location>
            <begin position="17"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="220"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="30388" checksum="F76493CDBFE40950" modified="2008-04-29" version="1">MAERKKWLPQTEEELTPFQLAMMALSLLSVIVVLVLSFAKLEPETKRLLTAVDFSICIIFLTYFFYGLARADDKVYYIKHNWIDFVASIPVIEPLRFARLFQILRVIRLIRMAQSFIVPMVKQRRQATLASLLVAMVTILTFSSVLILIVESGVPDANIQTAENAIWWALVTISTVGYGDYYPVTTAGHVIGGIVIICGVSFFGVISGYMASLFIAPDESEKIEAQSKEIRTELHDALERMEANQGMLLKQIDELQQELKQERSSSGKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE32</accession>
    <name>B1KE32_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323365.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0723"/>
    <dbReference type="EnsemblBacteria" id="ACA85018">
        <property type="protein sequence ID" value="ACA85018"/>
        <property type="gene ID" value="Swoo_0723"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0723"/>
    <dbReference type="eggNOG" id="COG3789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1863798_0_0_6"/>
    <dbReference type="OMA" id="WGEDEVN"/>
    <dbReference type="OrthoDB" id="1492700at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019231">
        <property type="entry name" value="DUF2170"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09938">
        <property type="entry name" value="DUF2170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15688" checksum="4D17BB3B8CABEA33" modified="2008-04-29" version="1">MNIHTIANHLNDLCDKSHTGLQFDCYPINGEVEVLQVNIVGREEIPVFVSVTENQVLCISYLWGEDEVNQERRLEMFETMLELNIPMPLSSFAKIDDKYVVYGALSVQSEMQEIELELSVLSDNCLEVIDEMADFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA6</accession>
    <name>B1KEA6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat shock protein DnaJ domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323439.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0797"/>
    <dbReference type="EnsemblBacteria" id="ACA85092">
        <property type="protein sequence ID" value="ACA85092"/>
        <property type="gene ID" value="Swoo_0797"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0797"/>
    <dbReference type="eggNOG" id="COG2214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103241_1_0_6"/>
    <dbReference type="OMA" id="SFWTRMQ"/>
    <dbReference type="OrthoDB" id="1233142at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021059">
        <property type="entry name" value="DnaJ-related_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12339">
        <property type="entry name" value="DNAJ_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="166"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="25869" checksum="B195BCE9EA3C4FF6" modified="2008-04-29" version="1">MLFAKGSAQTSPLITCEPEAGVTNIKGDNPLIWPLFSLLQNSNHSWKVHLLATELQAKGLMQDLDDDQDKALFKRNFLLMNALFQLQDILLPEHWLQVKAMEIQIFNIIPTNLESSLREDDALREYYLNWVNYDTCPNIIREMLESFWSRYEEYIGTNPNLMHKDQALKVFELNHDATNREVRRRWRKLALQWHPDRPDGNTVQFRKVCEAWQTLRENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KED6</accession>
    <name>B1KED6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2233"/>
    <dbReference type="EnsemblBacteria" id="ACA86514">
        <property type="protein sequence ID" value="ACA86514"/>
        <property type="gene ID" value="Swoo_2233"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2233"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_5_1_6"/>
    <dbReference type="OMA" id="TPLGIVW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="26"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="167"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="34585" checksum="AF76E235CA89E7A9" modified="2008-04-29" version="1">MSEPASLKKQDNTIASSGLSKMVPVAFLAVVIIWSTTPLGIVWSSESVHPSMAVLLRMIIALLLGSFILLIARIRLPLSKAALKLYGVSSIGIVGGMLLSYFAAKYLASGTMSLIFGLSPLLSGLLAQKILNEPKFGPMRSISLVVAFIGLGIVCSSKISLTSDSWIGLALVLAAVSLFSLSGVLIKTVKINIHPIASTVGALMISTPMFALAWILFDGTLPIDSWSERSLYAILYLGVFGSLIGFIAYFYILQNLSASTVALVTLITPAFAMMLGARLNGEIITSALILGAICVLLGLTLYQFGDKLLNRYRPSYQVDRTEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KED7</accession>
    <name>B1KED7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isocitrate lyase</fullName>
            <ecNumber evidence="1">4.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Isocitrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isocitratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Can also use Mn(2+) ion.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324859.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2234"/>
    <dbReference type="EnsemblBacteria" id="ACA86515">
        <property type="protein sequence ID" value="ACA86515"/>
        <property type="gene ID" value="Swoo_2234"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2234"/>
    <dbReference type="eggNOG" id="COG2224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038243_0_0_6"/>
    <dbReference type="OMA" id="ARFQWDM"/>
    <dbReference type="OrthoDB" id="152545at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="PTHR21631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="527" mass="58276" checksum="CD0941DD70AEBA39" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ1</accession>
    <name>B1KEQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3807</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326397.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3807"/>
    <dbReference type="MEROPS" id="C39.005"/>
    <dbReference type="EnsemblBacteria" id="ACA88066">
        <property type="protein sequence ID" value="ACA88066"/>
        <property type="gene ID" value="Swoo_3807"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3807"/>
    <dbReference type="eggNOG" id="COG2274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_6"/>
    <dbReference type="OMA" id="QQSHFIE"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02419">
        <property type="entry name" value="Peptidase_C39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033838">
        <property type="entry name" value="CvaB_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="10">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="172"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="486"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="520"/>
            <end position="527"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="726" mass="81206" checksum="1D1F0C1BCF2F1A9A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES4</accession>
    <name>B1KES4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326419.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3830"/>
    <dbReference type="EnsemblBacteria" id="ACA88089">
        <property type="protein sequence ID" value="ACA88089"/>
        <property type="gene ID" value="Swoo_3830"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3830"/>
    <dbReference type="eggNOG" id="ENOG5031H3S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_719426_0_0_6"/>
    <dbReference type="OMA" id="ENSAFWG"/>
    <dbReference type="OrthoDB" id="1076987at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="44356" checksum="A4040AEC4393A3AA" modified="2008-04-29" version="1" precursor="true">MNYTITALFLMVFALSGCQSTQNSNVSNNLYQADNRADSGRLSSLSFIHRQGALMAETFNQDKENAFYDWWDREHLLSYAHDRYPELTLSEEESFYRTVRTKFSNQINGTEMWRFEGVQGDNLVFSAYLTELPITVLIEYKYLQNIGQRELVVVNWRMLHHLTSGLDAYSSYLHNSEVLNQSGYFDLIQSAVNGIKKTEREVSELFDSLPEALKKDPTLLNDFLWASLEVVPNPSAEFFRQTYPYVPSLTPENSAFWGYLYMLQDDLEQFKYVRSMAMANLGYIQTNYALVGVLYSLQQQDYDYAFEQFSHYIKAQPNDAIAYAIYLNNLIDLGLHERASQVYQALRLQFNLELVPEDFVEVDPDKLSAFFYSDAMQKVSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET6</accession>
    <name>B1KET6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326431.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88101">
        <property type="protein sequence ID" value="ACA88101"/>
        <property type="gene ID" value="Swoo_3842"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3842"/>
    <dbReference type="HOGENOM" id="CLU_2371982_0_0_6"/>
    <dbReference type="OMA" id="ESWRINS"/>
    <dbReference type="OrthoDB" id="2025488at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11170" checksum="BE70B8C85A53A6A6" modified="2008-04-29" version="1">MEIVNIPQSVQKALLGEVPATLRFLYAHISSGTLHYRAVFTDDATDEHLECASVVLTELLADCPSNIQLEESIERNSSIHWRIGSGEHLLFLRHGELSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV8</accession>
    <name>B1KEV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase M19 renal dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323456.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0814"/>
    <dbReference type="EnsemblBacteria" id="ACA85109">
        <property type="protein sequence ID" value="ACA85109"/>
        <property type="gene ID" value="Swoo_0814"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0814"/>
    <dbReference type="eggNOG" id="COG2355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031404_2_0_6"/>
    <dbReference type="OMA" id="WMRNGRW"/>
    <dbReference type="OrthoDB" id="1145595at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="327" mass="36578" checksum="1C35EF3E2F6F0C1E" modified="2008-04-29" version="1">MYQDQIIIDGLQYCNWTRDYFITLRESGITAVHVTLAYHEDARQTLTQFGQWNRLFEQNNDLIMPVNGVEDIASAKASGRVGILFGAQNCSPIDDEIDLIEVMRKQGLLIMQLTYNNQSLLATGCYESVDSGVTRFGKQVIKEMNRVGMIIDMSHSAERSTLETIELSERPICISHANPSFAHDALRNKSNEVLTALGDSGGLLGFSLYPFHLPNGSQCQLNDFCEMVAKTADLIGVDRLAIGSDLCLNQPQSVLEWMRNGRWSKSMDYGEGSSSNSGWPAALPWFDAQNGMKNIYNGLLEHGFNQEETNQIIGGNWFNFLELSLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV9</accession>
    <name>B1KEV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">BCCT transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0815"/>
    <dbReference type="EnsemblBacteria" id="ACA85110">
        <property type="protein sequence ID" value="ACA85110"/>
        <property type="gene ID" value="Swoo_0815"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0815"/>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010118_6_4_6"/>
    <dbReference type="OMA" id="NFIPMAT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="530" mass="57139" checksum="48C9B947F68B102F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW8</accession>
    <name>B1KFW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325017.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86675">
        <property type="protein sequence ID" value="ACA86675"/>
        <property type="gene ID" value="Swoo_2397"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2397"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097157_2_0_6"/>
    <dbReference type="OMA" id="HFTEMEL"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="194" mass="22205" checksum="5DF981C1ECBD8309" modified="2008-04-29" version="1">MTIKDKVDGRLKRSEANRQLIIDAMINLVNRGNYMPTAQQVADTSGVSIRTVFRHFTEMELLYREIDDVVKPLYISYFKQDFKGDLQTRIKRLANAVVNGFSGGYHLSKVTTVLKWRSPVLQATYDYNQKMLRLYVLSMLPELKKCDSVTTELVVGMASFAFFERLHMDQGLSLAVCKKLIIAHLSSVFEAELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG06</accession>
    <name>B1KG06_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325055.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2435"/>
    <dbReference type="EnsemblBacteria" id="ACA86713">
        <property type="protein sequence ID" value="ACA86713"/>
        <property type="gene ID" value="Swoo_2435"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2435"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="PSGYGQM"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="32013" checksum="1D789A7783662BD9" modified="2008-04-29" version="1">MYKHLQSIATFIAVAEAGAFNKAADALGVQASVVSHHVSKLEEHLGTTLIYRTTRKVSLSEHGRILFEASKKWLDGTSQAVDQIMDAQDEAIGALNVSLPAFVPEPEVENAILNFIELHPHVSITLNYSDTLVDLVEDNFDLCIRLGNPPDSSFIARKLAQTQHILVASPNFISRHGMPQEPLQLTKLPYVSMDGLGDTLTLTRSKQKVEVHNTICQINTNNIYGAKAAAENSLGIGNLPVALCEKAIAEGKLVHILPNWKLSSFPLIAIWPDASRRHTLAKRLVNHIINAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG29</accession>
    <name>B1KG29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2459</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325078.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86736">
        <property type="protein sequence ID" value="ACA86736"/>
        <property type="gene ID" value="Swoo_2459"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2459"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_1_6"/>
    <dbReference type="OMA" id="LHMACCA"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="215" mass="23306" checksum="73E064097157F05A" modified="2008-04-29" version="1">MNIDTIILFAGIVFLIAIIPGPNALLVLFTALTKSRMQAFSNIAGVSIGFVVHAFISAQGLSLLLSQSTFAFTLFKWLGVGYLLWLGITNIRAGLKTKMLTLPTMKTEAAGKSQAREGLMGNFIKGFLTNMLNPKIVLFYLSIFPQFVSPQTVLADSMLLGVTQAIVVSAWFLVVILLAEQFKVFLTNAKTAKWMNYAAGSLFLGFGAKLATAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG78</accession>
    <name>B1KG78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3958</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326545.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3958"/>
    <dbReference type="EnsemblBacteria" id="ACA88215">
        <property type="protein sequence ID" value="ACA88215"/>
        <property type="gene ID" value="Swoo_3958"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3958"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_26_6"/>
    <dbReference type="OMA" id="NMQTIES"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="211"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="3">
        <location>
            <begin position="248"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="47441" checksum="DF0E0F490395E642" modified="2008-04-29" version="1">MFNDKLKKELKACQNAMTRNQAVIDAINNSVATILFTPEGIVKDANLLFLDVVGFSLDALKGKHHRELCDSDYAQTSEYQKFWERLRSGEVISGTFPRNDINGDRLWLEATYFPIKKNGTITEVMKIAAEVTEKKAKLDEQEAVFIALDKSMAVIEFNPDGTILKANSNFLGAVGYNLEQIKGKHHRMFCPDSFYHENPNFWAELASGDFKAGQFERKDSTGRVLWLRATYNPVFDESGKVVRVVKFATNITEKVEQERAIREAAEVAYSTSVKTAEIATKGADVLESTVSTSESISDQVVETSSSISQLNEQSKSIEAIVSTISDIADQTNLLALNAAIEAARAGDQGRGFAVVADEVRQLAARTSQSTAEIADVVKKNRELTTEATGKMSSVSESADKGKQQISQASAVMEEIRVGAENVAKTVSGLNVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG5</accession>
    <name>B1KGG5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dyp-type peroxidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323640.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1000"/>
    <dbReference type="EnsemblBacteria" id="ACA85293">
        <property type="protein sequence ID" value="ACA85293"/>
        <property type="gene ID" value="Swoo_1000"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1000"/>
    <dbReference type="eggNOG" id="COG2837">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044178_0_0_6"/>
    <dbReference type="OMA" id="CAEPNLH"/>
    <dbReference type="OrthoDB" id="837319at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006314">
        <property type="entry name" value="Dyp_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04261">
        <property type="entry name" value="Dyp_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01413">
        <property type="entry name" value="Dyp_perox_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51404">
        <property type="entry name" value="DYP_PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="35132" checksum="07946F452FECB60F" modified="2008-04-29" version="1">MDNQVMPREQLGVCAEGNLHSVYLMFNANDGVESQLRPCLANVAQYVYELSDQYADSAFNGFVAIGANYWDSLYPSARPAQLKPFPAMNADNRDAPALEYDLFVHIRCDRFDILHLVANEVCQMLEGLVELVDEERGFRFMDNRDLTGFVDGTENPKGRNRQEVALVGSEDEAFKAGSYIHVQKYAHNLSKWHRLPQKKQEDIIGRTKQDNIEYASADKPLTSHIKRVNLKDEQGNSMEILRQSMPYGSVKEQGLMFISNCGNSVNFEKMLESMVQGDGHGHHDHLLHFTQALTGSSFFAPSLDFMEKAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN6</accession>
    <name>B1KGN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323710.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1071"/>
    <dbReference type="EnsemblBacteria" id="ACA85364">
        <property type="protein sequence ID" value="ACA85364"/>
        <property type="gene ID" value="Swoo_1071"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1071"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457755_0_0_6"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="365"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="596" mass="67451" checksum="E948CC41187195CC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGW5</accession>
    <name>B1KGW5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ion-translocating oxidoreductase complex subunit B</fullName>
            <ecNumber evidence="5">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Rnf electron transport complex subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnfB</name>
        <name evidence="9" type="ordered locus">Swoo_2557</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5 6">Binds 3 [4Fe-4S] clusters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325175.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2557"/>
    <dbReference type="EnsemblBacteria" id="ACA86834">
        <property type="protein sequence ID" value="ACA86834"/>
        <property type="gene ID" value="Swoo_2557"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2557"/>
    <dbReference type="eggNOG" id="COG2878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063448_2_0_6"/>
    <dbReference type="OMA" id="DEENCIG"/>
    <dbReference type="OrthoDB" id="1619561at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00463">
        <property type="entry name" value="RsxB_RnfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007202">
        <property type="entry name" value="4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010207">
        <property type="entry name" value="Elect_transpt_cplx_RnfB/RsxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016463">
        <property type="entry name" value="RnfB/RsxB_Proteobac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42859:SF3">
        <property type="entry name" value="PTHR42859:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04060">
        <property type="entry name" value="FeS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005784">
        <property type="entry name" value="Elect_transpt_RnfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01944">
        <property type="entry name" value="rnfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51656">
        <property type="entry name" value="4FE4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S" evidence="8">
        <location>
            <begin position="32"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Hydrophobic" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005784-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="20284" checksum="D5DC72CB11A93827" modified="2008-04-29" version="1" precursor="true">MSGILIAIVLLTILALFFGVLLGFAAEKFKVEGDPLVDQLEALLPQTQCGQCGYPGCRPYAEAIAGGEKVNKCPPGGTATMEKLADMAGVEPEPLTVSEEVQVKKVAYIREDECIGCTKCIQACPVDAILGTGKQMHTVITDYCTGCDLCVAPCPVDCIDMLPITPTVKNWDWKLNAIPVQMLEEDTKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH66</accession>
    <name>B1KH66_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable alpha-L-glutamate ligase</fullName>
            <ecNumber evidence="7">6.3.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rimK</name>
        <name evidence="10" type="ordered locus">Swoo_4122</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RimK family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326707.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4122"/>
    <dbReference type="EnsemblBacteria" id="ACA88378">
        <property type="protein sequence ID" value="ACA88378"/>
        <property type="gene ID" value="Swoo_4122"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4122"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045509_1_1_6"/>
    <dbReference type="OMA" id="YEHKVFY"/>
    <dbReference type="OrthoDB" id="359914at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01552">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008503">
        <property type="entry name" value="Put_Zn_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023533">
        <property type="entry name" value="RimK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041107">
        <property type="entry name" value="Rimk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18030">
        <property type="entry name" value="Rimk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05618">
        <property type="entry name" value="Zn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="266"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="340"/>
            <end position="341"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="373"/>
            <end position="375"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="422"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="459" mass="50155" checksum="B6C8ED5BB174B8CB" modified="2008-04-29" version="1">MSNKIIVGSEEWCALPGLGIKAIKARVDSGAKTSSIHAINISTSKREDGTWVSYEVHPLQGGRKVALLCESKLIDRRVIKSSNGETEKRYVVREQLQLGEQSWEIELTLTNRANMGYRMLLGREAMGSKILVDPSSTCCLGEMSDDEAKELYGHVEVPRSGLKIGLLASNPNLYSNQRIIEAGQQRGHEMYFLNVKQCYMKLDASQPEVHYRDGRILNDLDAVIPRIRPSMTFYGCALTRHFESLGVMALNTSEAITRSRDKLFSLQLLQKNNLDIPTSGFANSPADTTDLIDMVGGAPLIVKLLEGTQGKGVVLAETRKAAESVINAFKSLKANLLVQEFIKEAQGKDLRCFVIDGKIVASIERTAAPGEFRANIHQGGTASLVQISPEERKLAIKAAKTMGLEVAGVDIIRSSKGPLLLEINSSPGLEGIETATGIDVASAMIDSIEKRLGWKKETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH85</accession>
    <name>B1KH85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycoside hydrolase family 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323739.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1100"/>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85393">
        <property type="protein sequence ID" value="ACA85393"/>
        <property type="gene ID" value="Swoo_1100"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1100"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_14_0_6"/>
    <dbReference type="OMA" id="VNDGPAY"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013540">
        <property type="entry name" value="ChitinaseA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02839">
        <property type="entry name" value="CBM_5_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08329">
        <property type="entry name" value="ChitinaseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766602" evidence="7">
        <location>
            <begin position="24"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="8">
        <location>
            <begin position="157"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="552"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="863" mass="92236" checksum="30C5C38315B472B3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHD8</accession>
    <name>B1KHD8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Sigma-70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoD</name>
        <name evidence="10" type="ordered locus">Swoo_1153</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1153"/>
    <dbReference type="EnsemblBacteria" id="ACA85446">
        <property type="protein sequence ID" value="ACA85446"/>
        <property type="gene ID" value="Swoo_1153"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1153"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_7_0_6"/>
    <dbReference type="OMA" id="RDAKKEM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007631">
        <property type="entry name" value="RNA_pol_sigma_70_non-ess"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04546">
        <property type="entry name" value="Sigma70_ner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="9">
        <location>
            <begin position="570"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="172"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="377"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="456"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="545"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="401"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="611" mass="69724" checksum="2FC89BD69FFAB10E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHN6</accession>
    <name>B1KHN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2644"/>
    <dbReference type="EnsemblBacteria" id="ACA86921">
        <property type="protein sequence ID" value="ACA86921"/>
        <property type="gene ID" value="Swoo_2644"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2644"/>
    <dbReference type="eggNOG" id="COG3531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097497_2_1_6"/>
    <dbReference type="OMA" id="MDPMCSW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="24098" checksum="A6D97256BAD0263D" modified="2008-04-29" version="1">MTSKMNSKPKLYYIYDPMCSWCWGYAPTWHKLKNALEESGITVKYKLGGLAPDSDEPMPEEMQVFLEQTWHKISAQLGTVFNYDFWQQCQPRRSTYPACRAALIAREHNLEQAMLQGIQTAYYLEAKNPSDLETLTDIAISIGLGSTEFIKQMHNEKLNQKLMSEIASTRQLPIQGFPSLVLVHDNQVRPIQVDYQNWQASYQDIINDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ7</accession>
    <name>B1KHQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326714.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4129"/>
    <dbReference type="EnsemblBacteria" id="ACA88385">
        <property type="protein sequence ID" value="ACA88385"/>
        <property type="gene ID" value="Swoo_4129"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4129"/>
    <dbReference type="eggNOG" id="ENOG50326KX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1401615_0_0_6"/>
    <dbReference type="OMA" id="AQPQSID"/>
    <dbReference type="OrthoDB" id="1514875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="194" mass="19984" checksum="BF59D739516CA31B" modified="2008-04-29" version="1" precursor="true">MDIRYFVALSMMGLSHSAYTDQTSSIGSGSFQNVQGRTAVNIAAGDQNVQANAHSIGPSVTLLSIQESLFNDPILDEYESINSSVIESQAFVGAQGLIGINQVSGRGNTQANLGTIELATVNGLGLSALGLSDSALTQVSSSPSPISVGQQASNSTDIALDSFSEVQGIVQLNQISGDGNTAINRFSLQLSSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI73</accession>
    <name>B1KI73_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T-protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1259</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tyrosine biosynthesis; (4-hydroxyphenyl)pyruvate from prephenate (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323897.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1259"/>
    <dbReference type="EnsemblBacteria" id="ACA85551">
        <property type="protein sequence ID" value="ACA85551"/>
        <property type="gene ID" value="Swoo_1259"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1259"/>
    <dbReference type="eggNOG" id="COG0287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036672_1_1_6"/>
    <dbReference type="OMA" id="EHDHGMT"/>
    <dbReference type="OrthoDB" id="533829at2"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00122">
        <property type="reaction ID" value="UER00961"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008244">
        <property type="entry name" value="Chor_mut/prephenate_DH_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011277">
        <property type="entry name" value="CM_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001499">
        <property type="entry name" value="Chor_mut_pdh_Tpr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01799">
        <property type="entry name" value="CM_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="4">
        <location>
            <begin position="103"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="379" mass="42213" checksum="5DC51755A3CAEF84" modified="2008-04-29" version="1">MNERTTAELENLRGLIDGVDQQLIHLLRKRLDLVAQVGAVKHGAGLPIYAPQREAAMLAKRREEAKKMDVSPQLIEDILRRLMRESYLNEKDIGFKQVNPDLGHVVIVGGSGKLGGLFSQMLVLSGYQVKVIDKDDWARADEIFDGAGLVLVTVPIGITCDLIKDKLTTLPQSCILADLTSIKGEPVEAMLAAHSGPVVGLHPMFGPDVGSLAKQVVVVCHGRQSAEYQWLLEQIQIWGARIVEAEPERHDKAMQLVQAMRHFSSFVYGLNLYKEEADIESLLQFSSPIYRLELAMVGRLFAQSPELYADIIFAQKESMQAIGDYLDNYSQALSLLQVGDRDAFVAQFKEVAQWFGDFAPQFQRESRAMLQSVNDMKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC9</accession>
    <name>B1KIC9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Phosphatase NudJ</fullName>
            <ecNumber evidence="6">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nudJ</name>
        <name evidence="8" type="ordered locus">Swoo_2704</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the Nudix hydrolase family. NudJ subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325317.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2704"/>
    <dbReference type="EnsemblBacteria" id="ACA86980">
        <property type="protein sequence ID" value="ACA86980"/>
        <property type="gene ID" value="Swoo_2704"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2704"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_6_1_6"/>
    <dbReference type="OMA" id="QPAGHLD"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004787">
        <property type="term" value="F:thiamine-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03675">
        <property type="entry name" value="Nudix_Hydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033713">
        <property type="entry name" value="NudJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17980" checksum="978A924F37C7909C" modified="2008-04-29" version="1">MKPRYRPNVTVACIVQCQDKYLMVEELIDGQTRYNQPAGHLEKGESITQACEREVFEETGIKLKVQELVGIYQFNPDDTLAFLRFTFFAQLSSCVNATPQDTDIQAAHWLTFDEIQALAAKLRSPLVLTSLDDARNKTHYPLELLNSQYLRLAPSQNA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KID1</accession>
    <name>HFLD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">High frequency lysogenization protein HflD homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hflD</name>
        <name type="ordered locus">Swoo_2706</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HflD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325319.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KID1"/>
    <dbReference type="SMR" id="B1KID1"/>
    <dbReference type="STRING" id="392500.Swoo_2706"/>
    <dbReference type="EnsemblBacteria" id="ACA86982">
        <property type="protein sequence ID" value="ACA86982"/>
        <property type="gene ID" value="Swoo_2706"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2706"/>
    <dbReference type="eggNOG" id="COG2915">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098920_0_0_6"/>
    <dbReference type="OMA" id="RYIISLM"/>
    <dbReference type="OrthoDB" id="870739at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3890.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00695">
        <property type="entry name" value="HflD_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007451">
        <property type="entry name" value="HflD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035932">
        <property type="entry name" value="HflD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38100">
        <property type="entry name" value="PTHR38100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04356">
        <property type="entry name" value="DUF489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101322">
        <property type="entry name" value="SSF101322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000132303" description="High frequency lysogenization protein HflD homolog">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00695"/>
        </source>
    </evidence>
    <sequence length="204" mass="22600" checksum="397FCC42C01391F1" modified="2008-04-29" version="1">MSELLDERTMAFAGILQAIGQVQHIARHGNSDNDSLAASLNTVLVTNPDSTSDVYADKTALNKGYQLIVNQLGDSKDKDVEITRYLVGILALERKLSRGNAMGLLAERINQVHRQLHHFSITDEQVIANFAGIYSDVISTLGPKIQISGNPEFLKQNQVQEKIRALLLSAMRSAVLWRQLGGKRRHLVFARKSILDIANKSLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIL3</accession>
    <name>B1KIL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326836.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4253"/>
    <dbReference type="EnsemblBacteria" id="ACA88509">
        <property type="protein sequence ID" value="ACA88509"/>
        <property type="gene ID" value="Swoo_4253"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4253"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_37_6"/>
    <dbReference type="OMA" id="ERRIMID"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="231"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="422" mass="47919" checksum="E349F991D5DC30A8" modified="2008-04-29" version="1" precursor="true">MPTAPRKKSSVNTMTSKLSIYFAFIAIIIGATLFVLSQAILYWLEDELNRRTLQQSAETAIVQFKHQASSPVIITNSTKAYNRIEDLPQKYHALTQYPLGFLDEIHDAGFEDLFFYHTEYTHDGKRYPLLLIMDAEHVELSSTEWRNINLVSIIVMLVLFVLFGYAITKLARRLITPVTQLSQQLKSTDPKTHFSVPDDAATEFTELASSLNYYRSENELLIRQEQAFAKYASHELRTPLTIIQGATKLLELDGDAKFHCRQRERIAKAATDMNQTIEALLSLVKHEQSEDANYRVFEQTEIEQIIEYLQPLADSKSITVKLVVNAEPKIQPSRPVMRMLLSNLLSNAINASDPSLITVEIDNSEIRVLDQGSKVSEQNKQEGHGLGLLIVDALCQRYNWRFSLVSRVPSGSIASLNFKNHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIL7</accession>
    <name>B1KIL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4257</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326840.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4257"/>
    <dbReference type="EnsemblBacteria" id="ACA88513">
        <property type="protein sequence ID" value="ACA88513"/>
        <property type="gene ID" value="Swoo_4257"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4257"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018914_0_0_6"/>
    <dbReference type="OMA" id="WQGAYLA"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="636" mass="70637" checksum="C94FA692B58579A4" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM8</accession>
    <name>B1KIM8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4268</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326851.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4268"/>
    <dbReference type="EnsemblBacteria" id="ACA88524">
        <property type="protein sequence ID" value="ACA88524"/>
        <property type="gene ID" value="Swoo_4268"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4268"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047522_1_1_6"/>
    <dbReference type="OMA" id="PDLMIPV"/>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="255"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="367" mass="41168" checksum="D9AC3E86F2FFF594" modified="2008-04-29" version="1">MKSLISDRVNGHSSQGELATSSAKYTTIAAWSLAVARTLSASGIEPNPVFEAAGLSLSQLESAPDSRVAIDLMTPFWRDIEAVTQLPSFGLKVGQYAYPMHFRALGRLMMTSDTLAQAFERLPSYYALISNSAAIKLQRTPQLIGFTITPLDGVEISHMAIDAFFSTLMHHGDLMIGDSRFIHSVDLMRTEPKDSSAWRDCFKAPVAFDRQENCMWMDRGMLERSTLMANPELAAENEHQVRQYLDQMQALSWREKSYQAIHAMLVTGEPTAAKVAQLYNISERSLSRYLKKEETSFRSLLQDKRKELAHYYLGQSELSVTQLADKLGYTCLSNFTRAFHLWYGISPSEYRAQRLSSSTADNGKDTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ13</accession>
    <name>B1KJ13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325369.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2757"/>
    <dbReference type="EnsemblBacteria" id="ACA87033">
        <property type="protein sequence ID" value="ACA87033"/>
        <property type="gene ID" value="Swoo_2757"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2757"/>
    <dbReference type="eggNOG" id="COG2982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005680_0_0_6"/>
    <dbReference type="OMA" id="QQPPAEW"/>
    <dbReference type="OrthoDB" id="167445at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008023">
        <property type="entry name" value="DUF748"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05359">
        <property type="entry name" value="DUF748"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1024" mass="112339" checksum="5ABBF7E507455C16" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ35</accession>
    <name>B1KJ35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-ECFsigma factor, ChrR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325391.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2779"/>
    <dbReference type="EnsemblBacteria" id="ACA87055">
        <property type="protein sequence ID" value="ACA87055"/>
        <property type="gene ID" value="Swoo_2779"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2779"/>
    <dbReference type="eggNOG" id="COG3806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090912_0_0_6"/>
    <dbReference type="OMA" id="PLHFTSG"/>
    <dbReference type="OrthoDB" id="1792151at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd20301">
        <property type="entry name" value="cupin_ChrR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012807">
        <property type="entry name" value="Anti-sigma_ChrR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025979">
        <property type="entry name" value="ChrR-like_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12973">
        <property type="entry name" value="Cupin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02451">
        <property type="entry name" value="anti_sig_ChrR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="155"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="26605" checksum="69F631DFDC20A2A5" modified="2008-04-29" version="1">MIKLHPKGPLLSSFVEGSLPASLSVVIASHIEMCPECQKQVELLTEQAANACFGESSTSATQSGLGPQVERLCEELMDSDIEASLSGSELSMLDAITSITEVEHSAETVDLAAIIDKEIEVSGAKFKVPRALRNIEIKPFQGLGKLSRSRLNIEDGDLRTSLLHIDKGGSVPTHTHKGFEVTLLLQGSFEDEMGVYQAGDFIWLDAEHTHQPVTKTGCVCLTVSNDAIHFTKGVSQLLNPIGQFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ58</accession>
    <name>B1KJ58_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphonate ABC transporter, periplasmic phosphonate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2803</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphate/phosphite/phosphonate binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325414.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2803"/>
    <dbReference type="EnsemblBacteria" id="ACA87078">
        <property type="protein sequence ID" value="ACA87078"/>
        <property type="gene ID" value="Swoo_2803"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2803"/>
    <dbReference type="eggNOG" id="COG3221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051472_6_2_6"/>
    <dbReference type="OMA" id="QVQLAWF"/>
    <dbReference type="OrthoDB" id="988224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030836">
        <property type="entry name" value="ABC_peri_PhnD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005770">
        <property type="entry name" value="PhnD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01098">
        <property type="entry name" value="3A0109s03R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04553">
        <property type="entry name" value="ABC_peri_selen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767120" evidence="3">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="284" mass="31391" checksum="2FF672D5216692C6" modified="2008-04-29" version="1" precursor="true">MGLFKMAALVALSSISSSVFAAVFTFTAIPDENESQLRTRFEKVAVYLEKELGVEVKYVPVKSYSAAVTAFRNNQVQLAWFGGLSGVQARRLVPGSEAIAQGNEDQFFQSYFIANNSAQIIPSDNFPNLNGVTFTFGSKGSTSGRLMPEFFIERNLGKKAKDVFKRIGFSGDHSRTITQVESGAYQVGALNYKVWETAVENGTVDVNKVKVIWQSPTYPDYQWTVREGVDSAFGDGFKQRLTQALLDMDDPELLASFPRKSFVPADNLDYEPIEKVAKAIGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG3</accession>
    <name>B1KJG3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326961.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88635">
        <property type="protein sequence ID" value="ACA88635"/>
        <property type="gene ID" value="Swoo_4383"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4383"/>
    <dbReference type="eggNOG" id="ENOG50334HX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762677_0_0_6"/>
    <dbReference type="OMA" id="IRHATNT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="363" mass="40863" checksum="29A411CE97918E59" modified="2008-04-29" version="1">MRALFLFVLFNFLTACVSYESSIPKGYTGEAVTISDTYSNKTLSSAHFFYVKEMNGKPMYNAVRSTNGASSGQGAKLVAVGYSRKVPKAKLTLKVAGEVFRAAPILYMFNADENYAIEGEIEFTPNKDEFYFVKGELSETYSAVWIEDIHGKVISKLEEGEKSDKAPELVVKSKVYDPVFTESVNVDELSNINLGESSELVKVRLGEPTKVSVIEGNFFKRTRDKTVFFYEDIAQFVFNGGPDFIKIATVIEIIPVVGGGESNLQRLKKEMSSTDPKELREYAKKYYKSDYIYPNALDVISQKIEEELKRLSDQNTDAVAWLIRVIGRSKNSDYIGFLNDISAQTSSTKIKRYANKMIEELEK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJK5</accession>
    <name>NUSB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nusB</name>
        <name type="ordered locus">Swoo_1386</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324024.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJK5"/>
    <dbReference type="SMR" id="B1KJK5"/>
    <dbReference type="STRING" id="392500.Swoo_1386"/>
    <dbReference type="EnsemblBacteria" id="ACA85678">
        <property type="protein sequence ID" value="ACA85678"/>
        <property type="gene ID" value="Swoo_1386"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1386"/>
    <dbReference type="eggNOG" id="COG0781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087843_4_1_6"/>
    <dbReference type="OMA" id="DRMPVVD"/>
    <dbReference type="OrthoDB" id="1574817at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0889">Transcription antitermination</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000092587" description="Transcription antitermination protein NusB">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <sequence length="134" mass="15257" checksum="18767698E44DE99C" modified="2008-04-29" version="1">MKPSERRKARRLAVQAIYSWQLSGNNIADVEHEFLTEQKIDGIDVTYFRELLSGTATKQAQIDELITPHIERPYDEVSPIEKAVLRLATYELTFRKDVPYKVAINEAIELAKAFGAEDGHKFVNGILDKIVGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ1</accession>
    <name>B1KJQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324070.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1432"/>
    <dbReference type="EnsemblBacteria" id="ACA85724">
        <property type="protein sequence ID" value="ACA85724"/>
        <property type="gene ID" value="Swoo_1432"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1432"/>
    <dbReference type="eggNOG" id="ENOG5032WND">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059150_0_0_6"/>
    <dbReference type="OMA" id="GRFRINW"/>
    <dbReference type="OrthoDB" id="1520094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="425" mass="47649" checksum="D95B1BED295CE542" modified="2008-04-29" version="1" precursor="true">MKRASRLLTALPWLLLALISWQPSLLAAPIPGLEPTKSWDLDGYIKYMGALTSPDSVSNSLDHLLHQRFNFEYRFDRKLSVNVSMRNRVFYGDRADIPGYGDAIGEDSGYWDLTSTWLDSGGLVGNTQFDRAYLDWKPNEFDGGNWQVRAGRFRVNWAMSTLWNPNDIFNAYSIYDIDYEERSGVDALLVSRKLGFASALDFVYNPNSESELSSYAMRYLSNYQGWDLQGLIGKSGFDHVIGAGFAGELFGAGFRGEFSYFDPQYERWPIEKTAMDVGQVGSPVSMNMLAPQALSSTSVSTLEMDYSFSSARNWMVRGSMLHISNPTESDSALLYLNLPLTARTLSFSQWTSYLDVSFDISALNRVTFSSSYYDDGSYFVGASTNHSLANNWSLLLVLQRFDGSSSSLFGQTPSSLGSVQLKWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK29</accession>
    <name>B1KK29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326986.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4408"/>
    <dbReference type="EnsemblBacteria" id="ACA88660">
        <property type="protein sequence ID" value="ACA88660"/>
        <property type="gene ID" value="Swoo_4408"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4408"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098637_3_0_6"/>
    <dbReference type="OMA" id="NICTENG"/>
    <dbReference type="OrthoDB" id="1986406at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="17417" checksum="EE17E9F5934528F1" modified="2008-04-29" version="1" precursor="true">MRRAKQLGFTLIELVVVIIILGLLAVTAAPKFINLQSDAKASTLEGFRAALQGANTLVFSKAAVAGEERIADAAGWAANTGNTAGVDIGTGTPIQTVYGYLPEDAAVIGAAMDVDSSEWVATAVPGGGLAFSPQGAPADTCNFVYVEATSTTEPTYTLYTPVGAQDPFAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK59</accession>
    <name>B1KK59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327016.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4438"/>
    <dbReference type="EnsemblBacteria" id="ACA88690">
        <property type="protein sequence ID" value="ACA88690"/>
        <property type="gene ID" value="Swoo_4438"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4438"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_0_6"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="476" mass="53782" checksum="50965108794C75F9" modified="2008-04-29" version="1">MAEFKYLKIVDEVIRAIELGIFSDRAGSNKLESVRRYAKEKGVGVSTVTQAYMELEKLGWIYSEPKRGYFVVSKKSAKQPDYGHSINRVHAQLELANAVQYSFNDPDITPLSCTAPSTVIDQELLLNRLHKQVLKLRPYKLMMQDPIEGLSELRYEICRHLLRSGQVFYQDQLLVTNGRQEGLLLALTAAKAVGKPLAVESPASFFFQAILKQFNADVIEVPMQEDYADELALLTKAYKQQRFDTYLVNPNFADPTGRVLSVADKQALIKWAIEHDVTLIEYDRGELYFGRSRPVTIASLAADADNCRVISIADFYDTISPSISLGYLLCVNTFSQCQFAKQTVAEEPSIALQHMVANLLANGEYQTLLGKLRAQMKLNHQKTKSLILPVLNPSIYISEPTGGPCIWFKLPEGYSSEVLWERVIKDKLSIAPGAMFSFSGAFDSYFRITFALPWNHKMELAMIRLAEIINEYTEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK89</accession>
    <name>B1KK89_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327046.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4469"/>
    <dbReference type="EnsemblBacteria" id="ACA88720">
        <property type="protein sequence ID" value="ACA88720"/>
        <property type="gene ID" value="Swoo_4469"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4469"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="MIEYPIF"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="302" mass="33376" checksum="1E616AF3157C1AC1" modified="2008-04-29" version="1" precursor="true">MLDTPIKLTDVSLKYRDFPALDGVSFEVAAGQTMALLGHNGAGKSSLIKIILGLISPTSGTVKVMGQNAASAKGKRKVNLGYLPEDVSFYNKLTGLEVLSYFAALKGVSRSRVTSLIEEFGLEYAQHRQLKTYSKGMKQRLGVAQAILSEPNILLLDEPTVGLDPQASQFLYGKINQLKYAGCAVVISTHELSLVESQLDRALIMSKGRRLALGSCYELRSASPLHTTINFSGLTKQVSGNAYLQQFYRDGLLHFRGEQKAELIQHLVSQCQIFDFEIKEPRLEDIYHELMGQENHSHAEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK92</accession>
    <name>B1KK92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polysulphide reductase NrfD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4472</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NrfD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327049.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4472"/>
    <dbReference type="EnsemblBacteria" id="ACA88723">
        <property type="protein sequence ID" value="ACA88723"/>
        <property type="gene ID" value="Swoo_4472"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4472"/>
    <dbReference type="eggNOG" id="COG3301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045348_1_2_6"/>
    <dbReference type="OMA" id="HAIEWPV"/>
    <dbReference type="OrthoDB" id="1903395at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005614">
        <property type="entry name" value="NrfD_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03916">
        <property type="entry name" value="NrfD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="315" mass="34109" checksum="15921C3F8ED595C9" modified="2008-04-29" version="1">MDGNIEFTMGLSQGIAWPWPIAVYLFFAGISGGALSVALFIRFYKKQTENTPFLKAASLVSLVTIALGMLCLVIDLTNPLFFWRILVFYNLNSVMSVGVLVLNAYIPLVALVTLFAFEEEIKAFKPLHFLLPIIDKLRVIRAPSEKLVLVLAMSVCAYTGFLISALIRFPIINTSVLPALFVASGLSAGAAAAKMIAVSVFKEDLHSKDMHTLHAIEWPVMAAEALFLFMIIMSLATGNAGAQAAFAGFHTGVWANVFWIGVVGIGFVGPLLLNFATGKAFSHSAKAFYMSGMCAVVGMMCLRMFVIYAGQLNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKU5</accession>
    <name>B1KKU5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327077.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4500"/>
    <dbReference type="EnsemblBacteria" id="ACA88751">
        <property type="protein sequence ID" value="ACA88751"/>
        <property type="gene ID" value="Swoo_4500"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4500"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030169_1_2_6"/>
    <dbReference type="OMA" id="HIGLYLT"/>
    <dbReference type="OrthoDB" id="803444at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764623" evidence="1">
        <location>
            <begin position="28"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="112"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="421" mass="45818" checksum="6245D08344281BAA" modified="2008-04-29" version="1" precursor="true">MGINTQLKTLLLSASLSALVSLPPAHAGQNNRQDQAPMASAKEAKIKHWRVPNSELKFTDISELKTAFIDSTPAAKQDGIAVGKLGLDAGNNEQIVALAKEIAAGKHGKFDSLLIAHRDKLLFESYFSRGRIDLPHPQSSASKVYISTIVGRAIQLGYLTMADLDKPLVSFLKNLDPSRFTKGAEKITLHKAMLMRSGIRISDEQAEKFRQSSPELKGQGLLQAYLEASAPITEASQSFKYQNDPMLVMQVIEAVVPGSAKKFIKTELLDKMGISNYGWSTHPVSGLPGDASMTSRAMLKFGKLAMNNGLWNGEQLIPAAYIARATDRLIYPNEAEIFGGGEAVSNQGYGYYWWGTDLTYDGKSYASASAQGGGGMYIMLIAELDLVIVVTAHERENTTQQLIAERILPAFVSQPDKLASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV6</accession>
    <name>B1KKV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327088.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4511"/>
    <dbReference type="EnsemblBacteria" id="ACA88762">
        <property type="protein sequence ID" value="ACA88762"/>
        <property type="gene ID" value="Swoo_4511"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4511"/>
    <dbReference type="eggNOG" id="ENOG50332RW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120464_1_0_6"/>
    <dbReference type="OMA" id="MRDYSYR"/>
    <dbReference type="OrthoDB" id="1572391at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764624" evidence="1">
        <location>
            <begin position="19"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="16878" checksum="8F5FB48E58D99A65" modified="2008-04-29" version="1" precursor="true">MRALILICSMFFVTLAQASFYQAGDQVTPIQLDDQFEKSVVVDANTDVILFSRGMAGGDLIKEALDKQISADKAVPATQVYLADISGMPSLIAKFVAIPQMKDLPFSIGLDKEGEVTKLLPAEKDRASLIRLDNLKVIEVSHFDSGEELFKALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW0</accession>
    <name>B1KKW0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327092.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4515"/>
    <dbReference type="EnsemblBacteria" id="ACA88766">
        <property type="protein sequence ID" value="ACA88766"/>
        <property type="gene ID" value="Swoo_4515"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4515"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_3_6"/>
    <dbReference type="OMA" id="LYWHARV"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="314" mass="35224" checksum="16899859F9CBB69F" modified="2008-04-29" version="1">MNHSDLKIIQGCDLNLLLSLTVLIEEGSVSKSAERLDISQPAMSQNLKKIRNLFDEPLFVKHGQGIKATEKARSLLPGLHEWLEMSSRLILQKAFDPKEVYGVVRIAFIDTMTSEIVPQLLEMVMQAAPNVELEFIHKPKHMFSMLESGELDLCIGGTETPPANIYGRKIGLERFCIASSPTHPINQLSNPSLADIFSFETAEYSASNAAEPQITQLAQANNLNRKVSFSTSSMLVLRNGLLAGKHIAFISDIVTQNPYWKDKLSILKHEALPEVESTLYWHARVHQDPLVQWFKNRCLELASGFREQGLYQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL09</accession>
    <name>B1KL09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327140.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4565"/>
    <dbReference type="EnsemblBacteria" id="ACA88815">
        <property type="protein sequence ID" value="ACA88815"/>
        <property type="gene ID" value="Swoo_4565"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4565"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_3_1_6"/>
    <dbReference type="OMA" id="NPGDYYL"/>
    <dbReference type="OrthoDB" id="154149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765015" evidence="1">
        <location>
            <begin position="24"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="446"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="657" mass="73880" checksum="298C5AB1AAC52B6B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL34</accession>
    <name>B1KL34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322724.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0074"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84375">
        <property type="protein sequence ID" value="ACA84375"/>
        <property type="gene ID" value="Swoo_0074"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0074"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065962_1_0_6"/>
    <dbReference type="OMA" id="YTELWAL"/>
    <dbReference type="OrthoDB" id="1379602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="29182" checksum="BD3D0DE8CB1D0732" modified="2008-04-29" version="1">MKLPISVFIITKNEEKHIEKTLQSVALLDEVILVDSGSTDGTLAIAERYGAKIYSHPWQGYAKQKQYAMSLCSHEWVLNLDGDEAINTSLIEAFKTIMEQDKADSVRFWRNDIFIDKPLSSWSKKPNNHRFYKRSKSFFDDSRLAHESATVDGKEIFINETFDHFGYCSIEAITSKNNSYSGLKADEKFAKGKKFSNLKLITVFPLIFIKEYFIQRKIFSGRRGFILAVMDAYYAFIKEAKLYEHHQLKDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL40</accession>
    <name>B1KL40_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322730.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84381">
        <property type="protein sequence ID" value="ACA84381"/>
        <property type="gene ID" value="Swoo_0080"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0080"/>
    <dbReference type="HOGENOM" id="CLU_550817_0_0_6"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="495" mass="56413" checksum="381382EF3FA9DF1C" modified="2008-04-29" version="1">MRYEASELELAFVSLNKNERPLWALAAVFISYVCMLFLMFFAEKYVGGTILHFIVQPFVVGFCTRYVGRLYSIKARAPSVILFAFLYICIGVLASLQALYFIALPIPMLIVFFTSRIKLTRVQEFALLEYQTTSLDIDLHPRSRKTLYAFLGVLFITALTVYWWTSNANSCMNALEGSNNSFVVESCSYNQFSSLEEMATIEDELSIDLFGTFSLPSPEALLIKEKAESGDVFYQRFYFVILAIFYQKSVLWEGNFIVERHREEVAYWSAITAADGFTPAMIKILNGLLDLPLVSEEQKLEAMDLAEELVINGSEEAYLLTLVGKLVTIEDVRQLFHQQSNTLDLLTEEQLENLMYAYKQGDYFYNLSDFDPSIEVEEPYTKSIRVPRQKDKVIDVLKVMSKKFNDTDASYQVAQMLLRESSLESIDFFTLAAEQGHAYAATKLGSLYFCSGRKVESLSWLKRAIKLGSKEAVAIQRKIIKGESLSVCQRGDRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH9</accession>
    <name>B1KLH9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Flagellar M-ring protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Swoo_1618</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">The M ring may be actively involved in energy transduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the FliF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324250.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1618"/>
    <dbReference type="EnsemblBacteria" id="ACA85904">
        <property type="protein sequence ID" value="ACA85904"/>
        <property type="gene ID" value="Swoo_1618"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1618"/>
    <dbReference type="eggNOG" id="COG1766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028108_1_1_6"/>
    <dbReference type="OMA" id="NYEVNRI"/>
    <dbReference type="OrthoDB" id="167675at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009431">
        <property type="term" value="C:bacterial-type flagellum basal body, MS ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013556">
        <property type="entry name" value="Flag_M-ring_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000067">
        <property type="entry name" value="FlgMring_FliF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046:SF0">
        <property type="entry name" value="PTHR30046:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08345">
        <property type="entry name" value="YscJ_FliF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004862">
        <property type="entry name" value="FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01009">
        <property type="entry name" value="FLGMRINGFLIF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00206">
        <property type="entry name" value="fliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0966">Cell projection</keyword>
    <keyword evidence="17" id="KW-0969">Cilium</keyword>
    <keyword evidence="17" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="15">
        <location>
            <begin position="60"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF_C" evidence="16">
        <location>
            <begin position="263"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA85904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="568" mass="62258" checksum="08D020EC0E2E0188" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLL2</accession>
    <name>B1KLL2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325645.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3038"/>
    <dbReference type="EnsemblBacteria" id="ACA87309">
        <property type="protein sequence ID" value="ACA87309"/>
        <property type="gene ID" value="Swoo_3038"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3038"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127639_0_0_6"/>
    <dbReference type="OMA" id="YGKFGWI"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14116" checksum="C265844E3B068AA2" modified="2008-04-29" version="1">MAKVIGLGGILFKSSNPKALAHWYQKHLQLPVESWGGAAFYLDKLSQYARSGYSVWSPMESDSEYLSPSQSSFMINLVVDDLTGALAQVQAGGCEVLEISEPSEFGRFGWFIDPDGNKVELWQPNISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLM9</accession>
    <name>B1KLM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325662.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3055"/>
    <dbReference type="EnsemblBacteria" id="ACA87326">
        <property type="protein sequence ID" value="ACA87326"/>
        <property type="gene ID" value="Swoo_3055"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3055"/>
    <dbReference type="eggNOG" id="ENOG5031IC3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152622_0_0_6"/>
    <dbReference type="OMA" id="FTTAYAW"/>
    <dbReference type="OrthoDB" id="1699669at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021378">
        <property type="entry name" value="DUF3010"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11215">
        <property type="entry name" value="DUF3010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="16729" checksum="A138706872BE2433" modified="2008-04-29" version="1">MRVCGVELKGGEAIICLLSYEGETFNVPDCRQQSFVISHSESTDSIRDFHFAFGKLMQDYSVDKVVVISREQKGKLAGSATSFKAEAAIQLLDIPVILMSPVTVKERLKRNPPMVDFDGLELKRFQKPAFDVAYAYHNQHIFNVWDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLR6</accession>
    <name>B1KLR6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325699.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87363">
        <property type="protein sequence ID" value="ACA87363"/>
        <property type="gene ID" value="Swoo_3092"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3092"/>
    <dbReference type="HOGENOM" id="CLU_1159651_0_0_6"/>
    <dbReference type="OrthoDB" id="2133033at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="29029" checksum="7A80E7CB18EFB8F7" modified="2008-04-29" version="1">MPVTGTEPELTKVAIETVQAVCSWKPEHYVEIIKEIAWPVVVLVISLRYKALIVTRVKALFENLQLGKLTLGTSGLSTEWQSNDKQKPPLTNNKIEGDLKSLSQIKLYQEQNDSEYIQDAILFVEKQLDYLNVPLEEQIKLLSAEYSILAATNRYVMINNAIYKSQYNLLVNLSLSTEAVTYQNLEIFFNALKADNPEHYEKTDTQLYLRFLIDWNLIKVENSLYSLTLFGFSYIKYMKKNENITHSFRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM01</accession>
    <name>B1KM01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327206.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4631"/>
    <dbReference type="EnsemblBacteria" id="ACA88881">
        <property type="protein sequence ID" value="ACA88881"/>
        <property type="gene ID" value="Swoo_4631"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4631"/>
    <dbReference type="HOGENOM" id="CLU_857644_0_0_6"/>
    <dbReference type="OrthoDB" id="2066480at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="37759" checksum="7DB8F7D5C5D16F36" modified="2008-04-29" version="1">MTKILAWSVVFIAAIWTIEAPDFEPIVAFVASLLTAITLQVKKSNDKQETEASPTIEESDNTFEVAEEEKTPEVNPVFKLAERFLEVFESHGVHLNEIPRCIPEKFGISLVELANKDKLIEKLTPDLIDWFCSIFNIRRDWLEANGNYIYDTKNYYKNEHSLLRLLKDLKEQHHSSMRVIAYKDVKELDSGGERPQDVNLLIVIPAFKIDDRLVMKYIPTSTQWDWGYWRSRYQFKGITRVCYKKLDLTFDGYNLDSEKMAELSSGGVFPKLIIDETPMGYTWYPDDYTDKETESRCAKETHENRSILDYIDEQRYADVFTDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM41</accession>
    <name>B1KM41_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA binding S1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0153</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0153"/>
    <dbReference type="EnsemblBacteria" id="ACA84454">
        <property type="protein sequence ID" value="ACA84454"/>
        <property type="gene ID" value="Swoo_0153"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0153"/>
    <dbReference type="eggNOG" id="COG2183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009833_0_2_6"/>
    <dbReference type="OMA" id="RWAWRTR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="3">
        <location>
            <begin position="675"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="741"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="755"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="802" mass="87149" checksum="C600B4435844FC42" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM48</accession>
    <name>B1KM48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0160</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322810.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0160"/>
    <dbReference type="EnsemblBacteria" id="ACA84461">
        <property type="protein sequence ID" value="ACA84461"/>
        <property type="gene ID" value="Swoo_0160"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0160"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_16_0_6"/>
    <dbReference type="OMA" id="MDGIWLA"/>
    <dbReference type="OrthoDB" id="1415498at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13136">
        <property type="entry name" value="MATE_DinF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PTHR42893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="444" mass="48668" checksum="69DE29ACCE6CDEC0" modified="2008-04-29" version="1">MTPVELLLNRQKNKQLLALALPMILSNITVPLLGLVDTAVVGHLSNAYYLGGVAVGSTIITLILWMLGFLRMATTGLVAQSFGAGDTQTQYKLLLQAGSLALILGVTAVVLQLPILNGALSLTDASAEVERYCREYFSIRIWSTPFALLNLVLLGWLLGRQQPRAAMWQLIVANLANIGLDVLFVLGLGWGVKGAALASVFADMAGFLVAFTMVYKELNKIGNFKFLALCKELNISSYHKLLTLNADIFIRSLCLQLSFAFMTFQGAGLGDKTVAANAVLLNLLLLISYALDGIAYYAEAEVGRAYGQKNRKLMQESVTLAWLWSGISAVLFTLLFAFGGESIIRLLTSIEDVRLVASEFLFWVVLLPLLSFGSYLFDGVYIGAAKGKVMRNSMIISTFGIFFPVWFLLQDNGNHALWAAMSAFMLARSLTLTLHYRYRLSKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH0</accession>
    <name>B1KMH0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1683</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324314.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1683"/>
    <dbReference type="EnsemblBacteria" id="ACA85968">
        <property type="protein sequence ID" value="ACA85968"/>
        <property type="gene ID" value="Swoo_1683"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1683"/>
    <dbReference type="eggNOG" id="COG1088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_14_6"/>
    <dbReference type="OMA" id="KLIPLMC"/>
    <dbReference type="OrthoDB" id="707977at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="6"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="363" mass="40610" checksum="9902A4CF3FFCFAF9" modified="2008-04-29" version="1">MSKTILVTGGAGFIGAALIRFLINETDNRVINLDKLTYAGNLLSLKDIEGDERYHFIHGDICDKTLVCQTLKHFQPDFIMNLAAESHVDRSIEGPSAFIETNILGTFSLLEAARSYCLTLSDEKRHGFRFHHISTDEVYGELGDTGYFTEESPYLPSSPYSASKAASDHLVRAWSRTYNLPVVLTNCSNNYGAYQYPEKLIPLVIMNALSGKPIPIYGDGKQIRDWLYVDDHVRALYCVVTKGEVGETYNIGGCNEKTNLEVVTAICELLEELALTNAYSSNEIDGGFSSLITYVTDRPGHDTRYAIDAGKIARELNWQPMESFNSGLRKTVIWYLENQAWCQSILSKPQNKPFSQNKPSEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI7</accession>
    <name>B1KMI7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324331.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1700"/>
    <dbReference type="EnsemblBacteria" id="ACA85985">
        <property type="protein sequence ID" value="ACA85985"/>
        <property type="gene ID" value="Swoo_1700"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1700"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_6_4_6"/>
    <dbReference type="OMA" id="NNACKIT"/>
    <dbReference type="OrthoDB" id="1864829at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12386" checksum="55601CBFC1A7F3A9" modified="2008-04-29" version="1">MKFSPLALNNACLVTLPKEMVITQTPTLRAAITHQIETGSNKLVLDLHQVEFIDSSGLSVLVSALKLTQKKAGEIILLSPSAGVRALIELTRLHHVFAIYEDRTAAIEHICEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMM0</accession>
    <name>B1KMM0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein MtrB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325734.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3127"/>
    <dbReference type="EnsemblBacteria" id="ACA87398">
        <property type="protein sequence ID" value="ACA87398"/>
        <property type="gene ID" value="Swoo_3127"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3127"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024976_0_0_6"/>
    <dbReference type="OMA" id="EWTQISI"/>
    <dbReference type="OrthoDB" id="95112at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020016">
        <property type="entry name" value="Decahaem-assoc_OM_MtrB/PioB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11854">
        <property type="entry name" value="MtrB_PioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03509">
        <property type="entry name" value="OMP_MtrB_PioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767499" evidence="1">
        <location>
            <begin position="25"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="698" mass="77958" checksum="C523659CF47773FC" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN00</accession>
    <name>B1KN00_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 19">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="6 19">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">murB</name>
        <name evidence="21" type="ordered locus">Swoo_4707</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 19">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 19">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the MurB family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="6 19"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327275.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4707"/>
    <dbReference type="EnsemblBacteria" id="ACA88957">
        <property type="protein sequence ID" value="ACA88957"/>
        <property type="gene ID" value="Swoo_4707"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4707"/>
    <dbReference type="eggNOG" id="COG0812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035304_0_0_6"/>
    <dbReference type="OMA" id="MQNIGAY"/>
    <dbReference type="OrthoDB" id="841869at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16 19" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9 19" id="KW-0132">Cell division</keyword>
    <keyword evidence="13 19" id="KW-0133">Cell shape</keyword>
    <keyword evidence="17 19" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 19" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 19" id="KW-0274">FAD</keyword>
    <keyword evidence="10 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12 19" id="KW-0521">NADP</keyword>
    <keyword evidence="15 19 21" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14 19" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="20">
        <location>
            <begin position="17"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="19">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ACA88957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="37428" checksum="5C7C9D95E1759916" modified="2008-04-29" version="1">MSAEQLHSLKAYNTFAIEHACVSIINADSKGGLVETCLGLHQAGKQFFVLGGGSNILLTEDYLGTVVRILTRGVEVSEDSSCYLLTVEAGENWHELVEYCLKLGISGLENLALIPGTVGAAPIQNIGAYGVEFVDVCDWVEYLDLTDGKLKRFNAAECDFGYRDSIFKRELKGLAVITSVGFKLSKRWQPKLDYGPLARFDIETVTPLQVFNCICETRMSKLPDPKVLGNAGSFFKNPIISTERYLALQKQYPTIVGYPVDGGTKLAAGWLIDNAGLKGFAIGKASVHEQQALVLVNKGGATGDDVMCLARYIIEKIYTLFSVTLEAEPRVIGAQGERELIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN74</accession>
    <name>B1KN74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0270</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322920.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0270"/>
    <dbReference type="EnsemblBacteria" id="ACA84571">
        <property type="protein sequence ID" value="ACA84571"/>
        <property type="gene ID" value="Swoo_0270"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0270"/>
    <dbReference type="eggNOG" id="COG1180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058969_3_1_6"/>
    <dbReference type="OMA" id="CHNPHTI"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040074">
        <property type="entry name" value="BssD/PflA/YjjW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023912">
        <property type="entry name" value="YjjW_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01118">
        <property type="entry name" value="activating_enzymes__group_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00392">
        <property type="entry name" value="YjjI_activase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04041">
        <property type="entry name" value="activase_YjjW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="16"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="32505" checksum="1A5B74743D4C525E" modified="2008-04-29" version="1">MSRVATVNQIIPFSCVDGPGSRLVIFLQGCNFNCKNCHNPYTIDMCNSCGDCVATCPVNALSLTSSKEGKSKIVWDSDLCTQCDICLSTCPKQSSPKTRQYSVPQILELIRAQVHFINGITISGGEATLQLPFIIELFQAIKASQDLMHLSCMIDSNGYLSEGGWLQVMPYLDGVMIDLKSWQQETHNYITGRDNHRVFSSLKLLAKHGKLYEIRLLHIPHVSDFDSEIDAVASYLTRLPANVRIKLNAFQHHGVTGESLNWPICSEEQMLELAARLTERGVANLVLPNVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN90</accession>
    <name>B1KN90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulator of RpoD, Rsd/AlgQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Rsd/AlgQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322936.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0286"/>
    <dbReference type="EnsemblBacteria" id="ACA84587">
        <property type="protein sequence ID" value="ACA84587"/>
        <property type="gene ID" value="Swoo_0286"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0286"/>
    <dbReference type="eggNOG" id="COG3160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142729_0_0_6"/>
    <dbReference type="OMA" id="DVIDHWL"/>
    <dbReference type="OrthoDB" id="1641028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038309">
        <property type="entry name" value="Rsd/AlgQ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007448">
        <property type="entry name" value="Sigma70_reg_Rsd_AlgQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04353">
        <property type="entry name" value="Rsd_AlgQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016548">
        <property type="entry name" value="Rsd_AlgQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="155" mass="17790" checksum="67B8A0A876529440" modified="2008-04-29" version="1">MLKQLEKAEQRWGGANTLIDHWLNNRRKLLINYCKIAGIPPYDSTEKSLPAITLVKEFCDQLMDYVSEGHFEVYDQVVTACEKNGVSSKELAQKLVPRISETTDSALDFNDKYTELVDDKVLFQLDKDLSSLGHAMETRFELEDKLLEVLHTKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF3</accession>
    <name>B1KNF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1745</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324376.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1745"/>
    <dbReference type="EnsemblBacteria" id="ACA86030">
        <property type="protein sequence ID" value="ACA86030"/>
        <property type="gene ID" value="Swoo_1745"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1745"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_28_0_6"/>
    <dbReference type="OMA" id="VCADEAP"/>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="44"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="246"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="399"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="432" mass="47387" checksum="C0BB4E9F0308DBE7" modified="2008-04-29" version="1">MAHSLPCETTNIARFDELGLIPELLQRIAELEYLTPTQIQSQSIPHLLEGKDLLGGANTGSGKTAAFALPILQHLHVGDKPVAKGNMVRALVLVPTRELAKQVAASFKSYAQGLTPKLKVEAVFGGVSVNTQMLALRGGADVLVATPGRLLDLLSSNAIKLSQASHLVLDEADRMLSLGFAEELEKVLALLPKRKQTLLFSATFPEEVKELTDSLLNSPVELHLESTEESTLVQQVYTVNKNRKTALLAHLINERNWRQVLVFASAKNTCNRLEQKLAKAGVSAQVFHSDKSQGSRTRVLDGFKSGEISVLIATDIAARGIDIEKLPVVINYELPRSPSDYMHRIGRSGRAGEAGLALSLISHDEYQHFKLIEKKNKIRLVREQIVGFEADEEAPLDCPSREIKPMAAPEGMGKKKRKKLPKVNAELWGKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNG4</accession>
    <name>B1KNG4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Sec translocon accessory complex subunit YajC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">yajC</name>
        <name evidence="11" type="ordered locus">Swoo_1757</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the YajC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324387.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1757"/>
    <dbReference type="EnsemblBacteria" id="ACA86041">
        <property type="protein sequence ID" value="ACA86041"/>
        <property type="gene ID" value="Swoo_1757"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1757"/>
    <dbReference type="eggNOG" id="COG1862">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116157_2_1_6"/>
    <dbReference type="OMA" id="GMEMIIM"/>
    <dbReference type="OrthoDB" id="2082059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="11918" checksum="CF79CDCC95B79BD6" modified="2008-04-29" version="1">MLISNAYAADAPVSGAGGTMELVFMLVIFGLIFYFMIFRPQSKRVKEHKSLMSSLGKGDEVLTSGGILGKIAKISDENDYVLLSLNETTEITIKKDYIAAVLPKGSIKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI2</accession>
    <name>B1KNI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, BadM/Rrf2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324405.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1775"/>
    <dbReference type="EnsemblBacteria" id="ACA86059">
        <property type="protein sequence ID" value="ACA86059"/>
        <property type="gene ID" value="Swoo_1775"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1775"/>
    <dbReference type="eggNOG" id="COG1959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107144_0_0_6"/>
    <dbReference type="OMA" id="YGLTIMM"/>
    <dbReference type="OrthoDB" id="1794390at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010242">
        <property type="entry name" value="TF_HTH_IscR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02010">
        <property type="entry name" value="IscR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="16474" checksum="D1C5BDA973408971" modified="2008-04-29" version="1">MKLTSKGRYAVTAMLDVAMHSTAGPVPLADISERQGISLSYLEQLFAKLRKQGLVSSVRGPGGGYRLGADAGEISVGMVVRAVDESVDATRCQGQGNCQSGTRCLTHSLWGDLSKQISDFLNGISLAGLMTKRDVQFISIKQDEIQQEQRVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL4</accession>
    <name>B1KNL4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta-hexosaminidase</fullName>
            <ecNumber evidence="9">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">N-acetyl-beta-glucosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nagZ</name>
        <name evidence="11" type="ordered locus">Swoo_1807</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324437.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1807"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86091">
        <property type="protein sequence ID" value="ACA86091"/>
        <property type="gene ID" value="Swoo_1807"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1807"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008392_0_0_6"/>
    <dbReference type="OMA" id="WQMAAEM"/>
    <dbReference type="OrthoDB" id="949956at2"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00364">
        <property type="entry name" value="NagZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022956">
        <property type="entry name" value="Beta_hexosaminidase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="10">
        <location>
            <begin position="10"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="164"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="9">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="36989" checksum="93DB0BAE69B1F10B" modified="2008-04-29" version="1">MSYLMLDLLSTQASAEELTQLKHPMVGGVILFSRNYTDRPQLVSLVESLRVVRPDLLIAVDHEGGRVQRFRDGFTHIPAMGDILPFAGGDMILAKKWAVELGFLMAVELLACDIDLSFAPVLDLNRVSEVIGKRAFSSEPNEVIELAGSFIEGMHQAGMASVGKHFPGHGSVVADSHIAQPYDERSKEEILELDMQPFKSLIAKDQLHGVMPAHVIYSKVDPNPAGFSSFWLQDILREQLSFRGVIFSDDLGMKGAGVVGGYKARAQAALDAGCNMILICNDAKGATEVLEELVWPTSQPEYPAQLLKPDSKIVAQALQNDERWQQAKLLASRFSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ5</accession>
    <name>B1KNQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325849.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3243"/>
    <dbReference type="EnsemblBacteria" id="ACA87513">
        <property type="protein sequence ID" value="ACA87513"/>
        <property type="gene ID" value="Swoo_3243"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3243"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_349466_0_0_6"/>
    <dbReference type="OMA" id="TSYWGEG"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764694" evidence="1">
        <location>
            <begin position="23"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="594"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="824" mass="91778" checksum="8E4EA6751E929DA7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP04</accession>
    <name>B1KP04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4786</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327352.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4786"/>
    <dbReference type="EnsemblBacteria" id="ACA89035">
        <property type="protein sequence ID" value="ACA89035"/>
        <property type="gene ID" value="Swoo_4786"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4786"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_6"/>
    <dbReference type="OMA" id="AEFSCKA"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="3"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA89035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="368" mass="41276" checksum="5F9621ADA4BCD760" modified="2008-04-29" version="1">MPQDVGDLYCQIKQDKQIRLDAEFVCKAGEVLAVVGPSGGGKSTLLRMIAGLNHPESGVIRYGDRDWFNDGDKIHLTPQQRHLGYVPQHFGLFPNLTALGNVVAALDHIPKAEREPRAKEWLERVNLHGLPDRLPANLSGGQRQRVALARALAREPSVLLLDEPFSAVDRETRERLYLELARLKSQLSIPVIMVTHDLNEALLLADNMILISQGKMLQQGIPHEVLTRPRTEAVAKQMGLRNIFDAYVIAQEEERQITWLKFGEHLIASTYFDSLEVGAKVRWVIPNQGIRFNSIKQGRLCRSFNKLEITIDSMLTMGETVRLIASVKGVKHQLHAEVPLHYSNKIGLVVGVVTEVAFKSELIHILEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP50</accession>
    <name>B1KP50_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4832"/>
    <dbReference type="EnsemblBacteria" id="ACA89081">
        <property type="protein sequence ID" value="ACA89081"/>
        <property type="gene ID" value="Swoo_4832"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4832"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099447_0_0_6"/>
    <dbReference type="OMA" id="VDRTTMT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="57"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="23939" checksum="FCC45B934312F7CF" modified="2008-04-29" version="1">MYTNLIHGLTPRNSCFEVDLYFQGLESLYMFQKFCKLVLKLTGWKISGALPTEHQYVAIVGPHTSNWDFIIGVLARGALGAKVNFLGKHQLFIPPWGWFFKAIGGTPVDRRKSNNLVDGVVHLFQDNPKFSLALAPEGTRSPVKRWKTGFYHIASKANVPIVTVGLDFGSKTVLIANGIDTTDNMLQDMDKIIDFYRSIKGCHPKVIPDFIPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA7</accession>
    <name>B1KPA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323026.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0378"/>
    <dbReference type="EnsemblBacteria" id="ACA84677">
        <property type="protein sequence ID" value="ACA84677"/>
        <property type="gene ID" value="Swoo_0378"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0378"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_6"/>
    <dbReference type="OMA" id="QIHVHAP"/>
    <dbReference type="OrthoDB" id="1821409at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="26264" checksum="A91AF556404FC23C" modified="2008-04-29" version="1">MMKTVVITGASRRLGLFLAEQFIARGDRVFAVSRSTSNEFTSIDSANFHAVQIHGYDKLGVEQAVTAIKPQVSHIDLLINNASVFEADPKDNQEIESKLTLFFQIHMLFPSLLTHELAPLLFDEKTPGLVVNMTDIYADNPSHQHSLYCSTKAGLENLTRSFAKKFAPGIRCNSIMPGPLKFLPEHSQAQKEQVLNATLLPFEAGFNPVFQTIEFILANPFVTGTAIKVDGGRSICRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPC3</accession>
    <name>B1KPC3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323042.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84693">
        <property type="protein sequence ID" value="ACA84693"/>
        <property type="gene ID" value="Swoo_0394"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0394"/>
    <dbReference type="eggNOG" id="ENOG502ZUIX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_983156_0_0_6"/>
    <dbReference type="OMA" id="CKRSLEQ"/>
    <dbReference type="OrthoDB" id="1132799at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="34748" checksum="1282FDF415E2F57B" modified="2008-04-29" version="1">MNEFNSFFSQGYWWLSLLGGLHCIGLGLYIRYIYRESNGNHKLLGSIFSLMGLYFFTGMLNRDNSPAPIHLVFTLIIPVYFLLMPLLYLYCYRSLNNIKRDIKLSKHFYPALIIAILVLIASIINQHFTVQLSNIPESGRLTFTHIGALGTLLPGILSIQTSIYFVLIIQMLKRYRGRSHKAHQESLQDIKFRWLLVLTFAMVCNWLVRTLLVILPFYLGDQISEMTQAMTRLQLLLTVYVLAIYGLKQITKAAYLRGKLTYANDRVSTPIKASSQLLNSEELNYLHQLMKDDKKESHKPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH2</accession>
    <name>B1KPH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferredoxin-dependent glutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1841</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324471.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1841"/>
    <dbReference type="EnsemblBacteria" id="ACA86125">
        <property type="protein sequence ID" value="ACA86125"/>
        <property type="gene ID" value="Swoo_1841"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1841"/>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026563_1_0_6"/>
    <dbReference type="OMA" id="CIGHPWE"/>
    <dbReference type="OrthoDB" id="151647at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024188">
        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027283">
        <property type="entry name" value="YerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006429">
        <property type="entry name" value="GOGAT_lg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500060">
        <property type="entry name" value="UCP500060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Glu_synthase" evidence="4">
        <location>
            <begin position="158"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="547" mass="60419" checksum="09BFE20AE528CC95" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPI3</accession>
    <name>B1KPI3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324482.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1852"/>
    <dbReference type="EnsemblBacteria" id="ACA86136">
        <property type="protein sequence ID" value="ACA86136"/>
        <property type="gene ID" value="Swoo_1852"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1852"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_3_0_6"/>
    <dbReference type="OMA" id="MEAPTGQ"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="9"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14599" checksum="0A144365BD894E6F" modified="2008-04-29" version="1">MHKSRLAALVIDSQVDDIEVANQFWENALGLMCISSTEDWSNKYAHLETCNNQPQVLIQKVNHESRVHLDIETDDINAEVARLEKLGAVVAEKFPRWVVMLAPTGHRFCVVNPQRTDFTTAENVNEWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM8</accession>
    <name>B1KPM8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1897"/>
    <dbReference type="EnsemblBacteria" id="ACA86181">
        <property type="protein sequence ID" value="ACA86181"/>
        <property type="gene ID" value="Swoo_1897"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1897"/>
    <dbReference type="eggNOG" id="ENOG503474Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147284_0_0_6"/>
    <dbReference type="OMA" id="MNAPQMK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766930" evidence="1">
        <location>
            <begin position="36"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="150" mass="16654" checksum="FFBDC0CE0185567C" modified="2008-04-29" version="1" precursor="true">MLNFVSQRFNSFCHLTGKSLLLVPVTLFLSASAMAADKPSEAELAFNEEVLECASYYQISSNVIVNMDAPQMKPVGERLLNSSKKAIALAEQYQSKDAVEKQLTVTKEKQLATLPNGKSLGPLMSKYKVACQTLLSEPQKRLDYWIMATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPP7</accession>
    <name>B1KPP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1916</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324546.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1916"/>
    <dbReference type="EnsemblBacteria" id="ACA86200">
        <property type="protein sequence ID" value="ACA86200"/>
        <property type="gene ID" value="Swoo_1916"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1916"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_12_2_6"/>
    <dbReference type="OMA" id="HEWGMEQ"/>
    <dbReference type="OrthoDB" id="357522at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025878">
        <property type="entry name" value="Acyl-CoA_dh-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020953">
        <property type="entry name" value="Acyl-CoA_DH_N_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12806">
        <property type="entry name" value="Acyl-CoA_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12418">
        <property type="entry name" value="AcylCoA_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcylCoA_DH_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="79"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="162"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="282"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_C" evidence="10">
        <location>
            <begin position="470"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="596" mass="64658" checksum="919B5524A625A9D2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ7</accession>
    <name>B1KPQ7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purE</name>
        <name evidence="7" type="ordered locus">Swoo_3321</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325926.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3321"/>
    <dbReference type="EnsemblBacteria" id="ACA87590">
        <property type="protein sequence ID" value="ACA87590"/>
        <property type="gene ID" value="Swoo_3321"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3321"/>
    <dbReference type="eggNOG" id="COG0041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094982_2_2_6"/>
    <dbReference type="OMA" id="SNSIDGW"/>
    <dbReference type="OrthoDB" id="1701464at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="16468" checksum="5A357CA011E6DD77" modified="2008-04-29" version="1">MKVGIIMGSKSDWPTMEHAAQMLDTFGIAYETRVVSAHRTPQLLAEYSSTAAERGIKVIIAGAGGAAHLPGMVAAHTSLPVLGVPVKSKALNGIDSLLSICQMPKGVAVGTLAIGDPGAANAGLLAAQILGCQQPEIFAKIEAFRQAQTDSVLLNPDPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPR1</accession>
    <name>B1KPR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325930.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3325"/>
    <dbReference type="EnsemblBacteria" id="ACA87594">
        <property type="protein sequence ID" value="ACA87594"/>
        <property type="gene ID" value="Swoo_3325"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3325"/>
    <dbReference type="eggNOG" id="ENOG5033KIS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1833853_0_0_6"/>
    <dbReference type="OMA" id="PDASTHW"/>
    <dbReference type="OrthoDB" id="1521793at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767542" evidence="1">
        <location>
            <begin position="23"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16485" checksum="04DEE507372DB2FF" modified="2008-04-29" version="1" precursor="true">MSLWRNQVLLLLGVCMLLSACASQPDTSRYCGTVSGYSEPDREQNIYRVVVTHLNGKPVISKPNYQLSPGVYEFTLAELIDSPTLKVKLAARTPKVLSVKVEANQRYHIAARFNTDKVYRGNNTAFWEPEVWLTQEHECELPEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS1</accession>
    <name>B1KPS1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oxaloacetate decarboxylase beta chain</fullName>
            <ecNumber evidence="12">7.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_3335</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:57724"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="EC" id="7.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7 12">Heterotrimer of an alpha, a beta and a gamma subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 12">Belongs to the GcdB/MmdB/OadB family.</text>
    </comment>
    <dbReference type="EC" id="7.2.4.2" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325939.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3335"/>
    <dbReference type="EnsemblBacteria" id="ACA87604">
        <property type="protein sequence ID" value="ACA87604"/>
        <property type="gene ID" value="Swoo_3335"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3335"/>
    <dbReference type="eggNOG" id="COG1883">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036168_0_0_6"/>
    <dbReference type="OMA" id="PMIADPK"/>
    <dbReference type="OrthoDB" id="662061at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015451">
        <property type="term" value="F:decarboxylation-driven active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005661">
        <property type="entry name" value="OadB_MmdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35806">
        <property type="entry name" value="PTHR35806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03977">
        <property type="entry name" value="OAD_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015658">
        <property type="entry name" value="MmdB_OadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01109">
        <property type="entry name" value="Na_pump_decarbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="9 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR015658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="39007" checksum="2EE4BE063A055A75" modified="2008-04-29" version="1">MDGLIAFWSESGIANFTGGQLFMMGVGALLLYLAIVKRFEPLLLLPIGFGAILANIPNGGFTDEGGLLYFAYHVGIETGIFPLLIFMGVGALTDFGALIANPKMLLLGAAAQFGIFATLIGAVALNFVPGFDFSMKDAGAIAIIGGADGPTAIFLASKLAPDLLGAIAVAAYSYMALVPLIQPPIMKLFTTEAERQIKMEQLREVSKKEKIIFPLMVLGLTILFLPAATPLVGMFCLGNLMRESGVVDRLSNTAQNELINIVTIFLGLAVGSKLSADKFLQIETLGILLLGAVAFAIGTATGVLMAKLMSKLSGGKINPLIGAAGVSAVPMAARVVNKVGLESNQHNFLLMHAMGPNVAGVLGSAVAAGVLIAVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ32</accession>
    <name>B1KQ32_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327462.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89145">
        <property type="protein sequence ID" value="ACA89145"/>
        <property type="gene ID" value="Swoo_4896"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4896"/>
    <dbReference type="eggNOG" id="ENOG5031ARV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045822_0_0_6"/>
    <dbReference type="OMA" id="NLRVCWE"/>
    <dbReference type="OrthoDB" id="935548at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="380" mass="43200" checksum="914EB5CF514375EC" modified="2008-04-29" version="1">MKELILTPLKNENRGGDIIRSCSISRLNEGKEETSSQILWFQFPKVTEAPASDDCDSYLLSMLLEGMKENRKIIVKGSVSLELLSNLVELQSAWNKWLPKKYNVVDIEVDLIREPELRKKGAVCAFSGGVDATFSVWRHSQKKHSYRSQQINLCALIHGFDIPLTEQKAFDNAFIRAEKTLLDLELKLVQIKTNYREISKVLWPHSHALALVAALNQLKYQAGTGLIGSSESYDSLVIPWGSSPITDHLLSSDEFTVIHDGASHNRTEKVSEIAEWTTGANNLRVCWEGDVKDKNCGKCEKCIRTKLNFLACGFSIPKCFPTDTNLTEQIIKLKFRNDVERTEWAEIIKHADKNNIKADWKKAANTVIKRKSWYNFIKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ41</accession>
    <name>B1KQ41_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP synthase I chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327470.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4905"/>
    <dbReference type="EnsemblBacteria" id="ACA89154">
        <property type="protein sequence ID" value="ACA89154"/>
        <property type="gene ID" value="Swoo_4905"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4905"/>
    <dbReference type="eggNOG" id="COG3312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121415_3_1_6"/>
    <dbReference type="OMA" id="YMYMQVE"/>
    <dbReference type="OrthoDB" id="2066401at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005598">
        <property type="entry name" value="ATP_synth_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03899">
        <property type="entry name" value="ATP-synt_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA89154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="13785" checksum="1430D0F3A0331153" modified="2008-04-29" version="1" precursor="true">MSKVLARRGRWSAYKLVLMQAAVAGGASIFFFATWGAQYGLSALAGGAIAVLPNFVFATLAFSHTGASSAGKVVKTFYWGEAVKLLLTIAMFSLVFINMEIGFMPLFVCYTLALIVHWTAPLYFKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB8</accession>
    <name>B1KQB8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Membrane fusion protein (MFP) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0475</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323122.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0475"/>
    <dbReference type="EnsemblBacteria" id="ACA84773">
        <property type="protein sequence ID" value="ACA84773"/>
        <property type="gene ID" value="Swoo_0475"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0475"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023976_8_0_6"/>
    <dbReference type="OMA" id="FLPWTQN"/>
    <dbReference type="OrthoDB" id="1395473at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006144">
        <property type="entry name" value="Secretion_HlyD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010129">
        <property type="entry name" value="T1SS_HlyD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01843">
        <property type="entry name" value="type_I_hlyD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00543">
        <property type="entry name" value="HLYD_FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="10">
        <location>
            <begin position="66"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="169"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="460" mass="51607" checksum="CE8657A860DB2D25" modified="2008-04-29" version="1">MSKKLTTHDLEMIDDVYGAMMTDAPSSHRLIIWTLVALATCFLIWAFFAELDQVTTGMGKVIPSSQVQIIQSLDGGIMQELYVQEGMIVTKGQALVRIDDTRFRSDFAQQEQEVYSLQANVKRLETELNSIVITDMAADWREQVRITKLPLQFSAELAELEPELIERQKDEYSGRLDSLSNQLEILARQIQQRQQETQELASKIRTLTKSYQLVSRELSLTRPLADKGIVPEVELLKLERTVNDIQGELATLRLLRPKVKASQDEAILKRREAVFAFSTETRTQLSDLQTKLSRMSEAQVGAQDKVNKAEIVSPVNGTIKSIYINTLGGVVQPGIDILEIVPSEDQLLIETKITPKDIAFLHPGLPAVVKVTAYDFTRYGGLNGTVEHISADTSQDEEGNSFYLVKVRTELSSLTRDDGTEMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC0</accession>
    <name>B1KQC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane adhesin like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0477</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323124.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0477"/>
    <dbReference type="EnsemblBacteria" id="ACA84775">
        <property type="protein sequence ID" value="ACA84775"/>
        <property type="gene ID" value="Swoo_0477"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0477"/>
    <dbReference type="eggNOG" id="COG2373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_222581_0_0_6"/>
    <dbReference type="OMA" id="THANCAR"/>
    <dbReference type="OrthoDB" id="413616at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="99"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044016">
        <property type="entry name" value="Big_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041690">
        <property type="entry name" value="Cadherin_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019960">
        <property type="entry name" value="T1SS_VCA0849"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19077">
        <property type="entry name" value="Big_13"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17892">
        <property type="entry name" value="Cadherin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03661">
        <property type="entry name" value="T1SS_VCA0849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="105"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Big_13" evidence="4">
        <location>
            <begin position="373"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Big_13" evidence="4">
        <location>
            <begin position="466"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Big_13" evidence="4">
        <location>
            <begin position="559"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Big_13" evidence="4">
        <location>
            <begin position="652"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="Big_13" evidence="4">
        <location>
            <begin position="745"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin_5" evidence="3">
        <location>
            <begin position="15449"/>
            <end position="15538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="436"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="529"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="622"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="716"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="741"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16297"/>
            <end position="16322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="16322" mass="1631992" checksum="B4E391B8216B51F7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC2</accession>
    <name>B1KQC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane adhesin like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323126.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0479"/>
    <dbReference type="EnsemblBacteria" id="ACA84777">
        <property type="protein sequence ID" value="ACA84777"/>
        <property type="gene ID" value="Swoo_0479"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0479"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_225671_0_0_6"/>
    <dbReference type="OMA" id="NAWTFNI"/>
    <dbReference type="OrthoDB" id="413616at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040853">
        <property type="entry name" value="RapA2_cadherin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010221">
        <property type="entry name" value="VCBS_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17803">
        <property type="entry name" value="Cadherin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01965">
        <property type="entry name" value="VCBS_repeat"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="443"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="570"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="675"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="793"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="2386"/>
            <end position="2481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="3229" mass="335312" checksum="121F3C6F5A72FD1A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD7</accession>
    <name>B1KQD7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323141.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0494"/>
    <dbReference type="EnsemblBacteria" id="ACA84792">
        <property type="protein sequence ID" value="ACA84792"/>
        <property type="gene ID" value="Swoo_0494"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0494"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153788_4_2_6"/>
    <dbReference type="OMA" id="NNARITT"/>
    <dbReference type="OrthoDB" id="2045552at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="91" mass="10419" checksum="2E5E9D57EE3B41A0" modified="2008-04-29" version="1">MLNLYTAFDVQMELRDFISQSRKLNKLSVEELSTRSGVPYGTIRKFETTGNISLRQFLMLYEAVGNLSKVRTLTKTDNEQPTSIEEVLKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE4</accession>
    <name>B1KQE4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0502</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323148.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0502"/>
    <dbReference type="REBASE" id="17471">
        <property type="entry name" value="M.SwoAI"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84799">
        <property type="protein sequence ID" value="ACA84799"/>
        <property type="gene ID" value="Swoo_0502"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0502"/>
    <dbReference type="eggNOG" id="COG0286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018284_4_0_6"/>
    <dbReference type="OMA" id="VWFYEHP"/>
    <dbReference type="OrthoDB" id="791672at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="5">
        <location>
            <begin position="140"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="493" mass="55691" checksum="B7C89953CBF2E970" modified="2008-04-29" version="1">MSISSAIKSIQDIMRKDAGVDGDAQRLGQMSWLLFLKVFDAQEEELELELDDYREPIPEQFLWRNWAADNQGITGEELLDFVNDELFPQLKNLTAPIDKNPRGYVVKEAFSDAFNYMKNGTLLRQVINKLNEIDFTDSKERHLFGDLYEQILKDLQSAGNAGEFYTPRAITKFIVAVTDPKLGESIMDPACGTGGFLACAFDHVKTNYVKSGEDHKTLQQQIFGVEKKQLPHLLCTTNMMLHGIEVPVQIKHGNTLNKPLSSWDDQVDVIITNPPFGGTEEDGIEKNFPSEMQTRETADLFLQLIIEVLATKGRAAVVLPDGTLFGEGVKTKIKKLLTEECNLHTIVRLPNGVFNPYTGIKTNILFFNKGQPTKDVWFYEHPYPAGVKNYNKTKPMKFEEFATELSWWGVETDGFASRVENEQAWKVSIDDIIARNYNLDIKNPHVGDVVSHDPQELLQDYAKQQADIQSLREQLKDILSAALSPKDSAGEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM1</accession>
    <name>B1KQM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Adenylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324606.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1976"/>
    <dbReference type="EnsemblBacteria" id="ACA86260">
        <property type="protein sequence ID" value="ACA86260"/>
        <property type="gene ID" value="Swoo_1976"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1976"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092618_1_1_6"/>
    <dbReference type="OMA" id="WVLDGNY"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="176" mass="20183" checksum="1FFB49BF2CCDA264" modified="2008-04-29" version="1">MKRVVIIGSSCSGKSTFAKQLADKLAMTYIELDQLHWLPDWAERPDPEFRALVDKVSAAESWVIDGNYSVARDILWPRATTIIWLNHSFELVLYRAVTRSIYRTSTKKPLFAGNVETFRHSFLSLDSIILWVLKTFHTKRARYANLLTSNELPGINIIELSGQKQVDAFLDNVKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQS0</accession>
    <name>B1KQS0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Natural resistance-associated macrophage protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326011.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3408"/>
    <dbReference type="EnsemblBacteria" id="ACA87676">
        <property type="protein sequence ID" value="ACA87676"/>
        <property type="gene ID" value="Swoo_3408"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3408"/>
    <dbReference type="eggNOG" id="COG1914">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020088_6_3_6"/>
    <dbReference type="OMA" id="IATFVNS"/>
    <dbReference type="OrthoDB" id="416257at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="397" mass="42232" checksum="4823EA22C26F5BFD" modified="2008-04-29" version="1">MSRSAPKIGPGAFIAAAFIGPGTVTLCTIAGVKFGYGLLWVMLLSIVATYTLQEMSARLGLITQKGLAAVIKEQINSTVLRNITLLLIFSAIVVGNIAYEAGNITGASLGLSAIFGESSLPFLPLLIGSVSAILLFIGSYKLLERVLIGLVIAMSLSFFITAILTKPDLGAVLSGLFTPQVSSQNILMVIGLIGTTVVPYNLFLHASLVKEVWQHPNELKFVKQDTLISIGFGGIISMAIIICAASIQGDSVENLLDLAKGLNPLFGTFSSLFLGIGLFAAGITSAITAPLAAAFVGQHCFGWKANLKDWRFRTIWLTVIIVGVISSSLQLKPIEIIKFAQIANGLLLPLLASLLLWIVNKTQVLGQYKNSLRQNLIGAVVIAITLVLSIKTLYSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU4</accession>
    <name>B1KQU4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326035.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87700">
        <property type="protein sequence ID" value="ACA87700"/>
        <property type="gene ID" value="Swoo_3432"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3432"/>
    <dbReference type="eggNOG" id="COG5587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036742_2_0_6"/>
    <dbReference type="OMA" id="YKTHQGA"/>
    <dbReference type="OrthoDB" id="1258218at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
        <property type="entry name" value="UCP028451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028451">
        <property type="entry name" value="UCP028451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02453">
        <property type="entry name" value="TIGR02453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="223" mass="25574" checksum="7F7D0BCCB52734C8" modified="2008-04-29" version="1">MFSPNTFSFLSLLTKNNQRDWFKSNQTQYESEVRTPALQFIEAMQPHVLTLSPRLVALPKKIGGSLMRPQRDARFSKDKTPYKTNVGIQFRHFQGKDVHAPGLYIHIANEGCFLGAGIWHPDSKALNKLRTCIDENPNAYKKALAQLRAAGFEMEGDSLIRPPKGYDKTHPMLDELKRKDFIAIKPINAKQIYDKNFVSLCVKEFEQTQKLMGYLCFALDLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQW5</accession>
    <name>B1KQW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Porin Gram-negative type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326056.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3454"/>
    <dbReference type="EnsemblBacteria" id="ACA87721">
        <property type="protein sequence ID" value="ACA87721"/>
        <property type="gene ID" value="Swoo_3454"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3454"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038238_3_0_6"/>
    <dbReference type="OMA" id="MYGDAKL"/>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001702">
        <property type="entry name" value="Porin_Gram-ve"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002299">
        <property type="entry name" value="Porin_Neis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00182">
        <property type="entry name" value="ECOLNEIPORIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00184">
        <property type="entry name" value="NEISSPPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767307" evidence="5">
        <location>
            <begin position="25"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="6">
        <location>
            <begin position="12"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="315" mass="34233" checksum="40EE2658AA7E3DBD" modified="2008-04-29" version="1" precursor="true">MMNAFCKTLLASALATATLASANAAEPLTVYGKLNVTAQSNDVADESETTIQSNASRLGAKGSFELSSSLEAFYTIEYEVDTGDEAKENFKARNQFVGLKGNFGAFSVGRNDTMLKQSQGKIDQFNDLSADLKNLFKGENRIEQTATYLTPTFNGFKVGVTYAAEAAKSQYAQDGFSVAAMYGDAKLKKSPIYASIAYDSDVKGYEVVRATVQGKVAGFKLGGMYQQQEETYSKTGEAVNGDSKTGYLFSAAYTIDAVVLKAQFQDMEDKGDSWSIGGDYKLGKPTKLFAFYSSRSYEGEENDDKFFGVGLEHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQY0</accession>
    <name>B1KQY0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3470"/>
    <dbReference type="ESTHER" id="shewm-b1kqy0">
        <property type="family name" value="NLS3-Tex30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87736">
        <property type="protein sequence ID" value="ACA87736"/>
        <property type="gene ID" value="Swoo_3470"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3470"/>
    <dbReference type="eggNOG" id="COG3571">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072792_1_2_6"/>
    <dbReference type="OMA" id="HSFKPRK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026555">
        <property type="entry name" value="NSL3/Tex30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13136">
        <property type="entry name" value="PTHR13136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="82"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="24697" checksum="270FFE2E1F2A2BF0" modified="2008-04-29" version="1" precursor="true">MNYFLVKEPLEAESLLESHCVIDGELNDTLVIFTHGAGANLSSDFMQRMATGLSQSGIGVIRFNFPYMRANALDGKRRPPDRAPKLLKDFNLHIEAIKAQYSPKRIVLMGKSMGGRMAAIVAELTPVDGVICLGYPFVPLKGGDPRLEPIELCKAPLCVIQGERDKFGGKELVSSWPVMKKTQLHWLTDGDHSFVPRKSSGVTEEDNLTSAISYCIDFIRGLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR33</accession>
    <name>B1KR33_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323198.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0554"/>
    <dbReference type="EnsemblBacteria" id="ACA84850">
        <property type="protein sequence ID" value="ACA84850"/>
        <property type="gene ID" value="Swoo_0554"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0554"/>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040540_0_0_6"/>
    <dbReference type="OMA" id="TIDWGDK"/>
    <dbReference type="OrthoDB" id="1369011at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765141" evidence="2">
        <location>
            <begin position="24"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="449" mass="48506" checksum="A21E6FA18B340ED7" modified="2008-04-29" version="1" precursor="true">MKKTIIASLLLAYMAGGALHVQAETADSNLAVERTTAASITQNSQTPIAQSEAMADFSVWLPELMQDFNALPEVRAQEAKRKQASLMIKAADQAVYNPELGLGYQNASEDTYSLDISQTIDWGDKRGAATRKAQLQAEILLSDIALERSQMLANTLLALVEQSQASKALAFQKQQLVSAKTQLKIAVQQMELGDLSAVELQLIQLDVASKAADYAVAEQASITADADVLMLLGSSELPFNGFLGALTTSLVSKQVSPQLPALKSAYQQVLLAKVAAQQVKADTSADPTISLSAEREGEENKLGVGLSIPLQIRNNYSDTLAVAGQEIAVAEQSYLARERVLTQQQKKFNLSLPRLTERYQEWRELVFHSGQEAASALGQQWKAGDINTSDYLQSQRQLSSSFLAGLSLETALYSSWLEWMGASGQLDSFLSAQLPADSSATANTSTLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR49</accession>
    <name>B1KR49_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0570"/>
    <dbReference type="EnsemblBacteria" id="ACA84866">
        <property type="protein sequence ID" value="ACA84866"/>
        <property type="gene ID" value="Swoo_0570"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0570"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_813289_0_0_6"/>
    <dbReference type="OMA" id="IVLYPHF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="39114" checksum="D0D285FB5DA9F5A2" modified="2008-04-29" version="1">MFALPALRFLAGSTAYKTIAENGLKADLFTQVLAASGGPKWIGIAGLDRYLFGEFFKGRTAPLHTLGASSGAWRLACLGQADPLSAYSRLEELYIEQRYDTKPTPVQVSTQVKGIIEGLLGQSGAQELISHPVIKTHLLACRGRHLNRIAGRLPLSLGLAATAATNLASRRSLGLHFERFVFSGQHDDSPFNQLKDLPSQQVKLTLDNLHNVLLATGSIPWVLAPVTDIHGAPKGHYYDGGITDYHFDLPLSHADGLTLYPHFYPNMTPGWFDKSLPWRKANKNYHNALVLAPTSEFLASLPYGKLPDRSDFKHLSSDERIAYWQQALAMSHRLADELSLVISKGNIMEYLEHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRB0</accession>
    <name>B1KRB0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2033</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324663.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2033"/>
    <dbReference type="EnsemblBacteria" id="ACA86317">
        <property type="protein sequence ID" value="ACA86317"/>
        <property type="gene ID" value="Swoo_2033"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2033"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_1_1_6"/>
    <dbReference type="OMA" id="PKTHVYR"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="319" mass="36366" checksum="B80975B6666C3979" modified="2008-04-29" version="1">MNSESPKIKVQLVTIDEDHVGQRIDNFLLTKLKGVPKSMIYRIVRKGEVRVNKKRIKPEYKLQDGDIVRVPPVRVSEKDERPGPSANLSKVSQLEERILFEDKHLIVLNKPAGLAVHGGSGVDFGIIEAMRSLRPTQKFLELAHRLDKDTSGVLLIAKKRSALRHLHDQLRFKKMQKDYQALVKGTWQARDKAIKAPLLKLTLKSGERIVRVNQEGKECETRFKILQRYQGSTLVQASPVTGRTHQIRVHCQYTGHPIACDEKYSEQKYDDSMRALGLNRLFLHAAQLRFTHPGNEEVMIVKAPLDPVLTQTLDKLIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRI4</accession>
    <name>B1KRI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324736.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2107"/>
    <dbReference type="EnsemblBacteria" id="ACA86391">
        <property type="protein sequence ID" value="ACA86391"/>
        <property type="gene ID" value="Swoo_2107"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2107"/>
    <dbReference type="eggNOG" id="ENOG5032RSM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066780_2_1_6"/>
    <dbReference type="OMA" id="LATWFHE"/>
    <dbReference type="OrthoDB" id="1544298at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="234" mass="25992" checksum="66187802529CB605" modified="2008-04-29" version="1">MHNSSVNPLEQEKLERSGAPSRGRFFFELMFAFLITRLPYISVPFKWLESYFHELSHGLASLVTGGSVSHIQLFPNGAGLCFTQGGWPIAIGFSGYFGAALWGYLIFILATWPKGIRVSFAFLGSAVVLTTLLWGRDLLTISILACLAVLFLLPLKLNNNRFMDSGLRVMALMIMLNALASPTVLLGLSGKGDASMLASQTWIPAWVWVFVWLVISALMIFLCWRRVDQAALKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRN2</accession>
    <name>B1KRN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TMAO reductase system periplasmic protein TorT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326130.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3533"/>
    <dbReference type="EnsemblBacteria" id="ACA87797">
        <property type="protein sequence ID" value="ACA87797"/>
        <property type="gene ID" value="Swoo_3533"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3533"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053104_0_0_6"/>
    <dbReference type="OMA" id="ISQIEDC"/>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014301">
        <property type="entry name" value="TMAO_TorT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02955">
        <property type="entry name" value="TMAO_TorT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_1" evidence="1">
        <location>
            <begin position="44"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="352" mass="39476" checksum="FDDC80D763ADB3C9" modified="2008-04-29" version="1">MPLLFALQVNSETWPLEQRTPYNTKVQTASSLLYTPLKQTQKPWKICALVPHLKDAYWIGIDYGLVQQATKLNIKLELFEAGSYYHKKKQLEQLSNCMKEDFDAILLGTVDPKLIAYYHGPITKPVIALVNRVDSPTITTRIGVNWYQMGWHAGQFIKNDLAQTPTSSRKKQKDLALLTGPEKLGGSDWVDQGVFDALKESDIKISSIRHADNNRDLYRDQLHHLLDDQSPDYILGSAVAIEAAIGEIGHKHLEGKVKLVSSYLSPGVLRGLFRNKVSFSSDDLVVLQGKLAIDIVVRELEGKAVHGDIGPKIQSINAQELNKDKIKNKLSKSLAPAHFYPVYSVTPNNRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRN6</accession>
    <name>B1KRN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3537"/>
    <dbReference type="EnsemblBacteria" id="ACA87801">
        <property type="protein sequence ID" value="ACA87801"/>
        <property type="gene ID" value="Swoo_3537"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3537"/>
    <dbReference type="eggNOG" id="ENOG502ZC6N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108537_1_0_6"/>
    <dbReference type="OMA" id="WACVNAR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025368">
        <property type="entry name" value="DUF4272"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14094">
        <property type="entry name" value="DUF4272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="24084" checksum="C789EF01000548D8" modified="2008-04-29" version="1">MIMNLRTLKIQNESKLLSEGIVVNPNLPIIEELSEVSPRIASDVASRICAMSYVVGLAFDAVPEHLIQNLKQYSLWGFVTEQEQELLLLEQIPKEEFNELTWMPESIQALVWSLGLIGMDHHMYCDDKLASIVPPYCDPAGFIKNAELKPITQIQEQCDLLYRLHWYSKHCRINGIECLYDESIISERRKALDWVYGVTVNWDDIPMDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCV6</accession>
    <name>B1KCV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0030"/>
    <dbReference type="EnsemblBacteria" id="ACA84331">
        <property type="protein sequence ID" value="ACA84331"/>
        <property type="gene ID" value="Swoo_0030"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0030"/>
    <dbReference type="HOGENOM" id="CLU_2865369_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="64" mass="7392" checksum="0E415BDA10422343" modified="2008-04-29" version="1">MYGIKNQLRTSNSTGSLGIYMNLDELANSVSESELRERLIHSVGEWKQDDQDIEELAYLMGKWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ2</accession>
    <name>B1KCZ2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-ketoacyl-CoA thiolase</fullName>
            <ecNumber evidence="8">2.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetyl-CoA acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-ketothiolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Fatty acid oxidation complex subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fadA</name>
        <name evidence="13" type="ordered locus">Swoo_0020</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + an acyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322670.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0020"/>
    <dbReference type="EnsemblBacteria" id="ACA84321">
        <property type="protein sequence ID" value="ACA84321"/>
        <property type="gene ID" value="Swoo_0020"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0020"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_2_3_6"/>
    <dbReference type="OMA" id="EPMRPGT"/>
    <dbReference type="OrthoDB" id="550338at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01620">
        <property type="entry name" value="FadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012805">
        <property type="entry name" value="FadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02445">
        <property type="entry name" value="fadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="11">
        <location>
            <begin position="5"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="12">
        <location>
            <begin position="262"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="8 9">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA84321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="387" mass="40828" checksum="051AE158464E8F44" modified="2008-04-29" version="1">MKQAVIVDCIRTPMGRSKAGVFRNVRAETLSAELMKALLARNPKLDPKDIEDVIWGCVQQTLEQGFNIARNAALLAGIPKEAGAVTVNRLCGSSMDALHQAARAIMTGQGDTFIIGGVEHMGHVPMNHGVDFHPGLANNVAKASGMMGLTAEMLGKMHGISREQQDEFAVRSHQRAHAATVEGRFANEIHPVEGHDANGVLIKVEHDEVIRPETSMESLSGLRPAFDPANGTVTAGTSSALSDGASAMLVMEEEKAKALGLPIRARIRSMAVAGCDAAIMGYGPVPATKKALERAGLTIDDLDVIELNEAFAAQSLPCVKDLGLMDVVDEKINLNGGAIALGHPLGCSGARISTTLINLMEAKDAKYGLATMCIGLGQGIATVFERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ9</accession>
    <name>B1KCZ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [quinone]</fullName>
            <ecNumber evidence="5">1.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [menaquinone]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [ubiquinone]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen oxidase</fullName>
            <shortName evidence="5">PPO</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hemG</name>
        <name evidence="7" type="ordered locus">Swoo_0027</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a menaquinone + protoporphyrinogen IX = 3 a menaquinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:27409"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.5.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a quinone + protoporphyrinogen IX = 3 a quinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:65032"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a ubiquinone + protoporphyrinogen IX = 3 a ubiquinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:63936"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5">Binds 1 FMN non-covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HemG family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322677.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0027"/>
    <dbReference type="EnsemblBacteria" id="ACA84328">
        <property type="protein sequence ID" value="ACA84328"/>
        <property type="gene ID" value="Swoo_0027"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0027"/>
    <dbReference type="eggNOG" id="COG4635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094839_0_1_6"/>
    <dbReference type="OMA" id="HKSVFEF"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070819">
        <property type="term" value="F:menaquinone-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00853">
        <property type="entry name" value="HemG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044264">
        <property type="entry name" value="HemG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 5" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_5" evidence="6">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="20558" checksum="8E787228903EC783" modified="2008-04-29" version="1">MKSILVLYYSRGGHTAKISRAIAEHIEHQGHKSRVMHISEAVKEGLDWAKYDSVALGACVMYGSYDKSVFAFTTEHQAALSEKPNSFYSVNVVARNPEKRVPENNKYLQKFIELSPWKPNDVKVIAGKVDYPAWRWWDRLAIQLIMKMTNGPTDPKSVIDYTDWDDVKLYAEHLIRLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD56</accession>
    <name>B1KD56_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326224.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87891">
        <property type="protein sequence ID" value="ACA87891"/>
        <property type="gene ID" value="Swoo_3627"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3627"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="AKCCRYL"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="37687" checksum="79A831005274F54A" modified="2008-04-29" version="1">MPRPRRTQMSIEDTSWYHCCSRVTRRARLFGNDELTGKNYDYRRDWVESLLLKLGDIFAIDVAAYAVMSNHLHLVLQIDIELANRWTDREVVEQWHQLFNGTELTQRFAKGEVIEEYQVAKLKHLVAIYRSRLCDISWFMRCLNEPIARMANKKDKCTGRFWEGRFKSQALLDEAAVLACMAYVELNPIRAQMADTLESSDNTSIQLRVNAALKGEQPTQLLPFIGDERLNQPKGINFALKDYLELVDETGRIIRNDKRGSISANSTKILTRLNISSDNWIKLTSEFGELFRGPVGNTQELTSFCEHLQKRRRHFAKCCKYLEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD7</accession>
    <name>B1KDD7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Curli production assembly/transport component CsgF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in the biogenesis of curli organelles.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323285.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0642"/>
    <dbReference type="EnsemblBacteria" id="ACA84938">
        <property type="protein sequence ID" value="ACA84938"/>
        <property type="gene ID" value="Swoo_0642"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0642"/>
    <dbReference type="eggNOG" id="ENOG5032U3R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136740_0_0_6"/>
    <dbReference type="OMA" id="DIAFGEQ"/>
    <dbReference type="OrthoDB" id="2085706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018893">
        <property type="entry name" value="T8SS_CsgF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10614">
        <property type="entry name" value="CsgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766473" description="Curli production assembly/transport component CsgF" evidence="4">
        <location>
            <begin position="20"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="130" mass="13745" checksum="346210A2BE953451" modified="2008-04-29" version="1" precursor="true">MKYRMLVLAASLVAGSVQSTELVYTPINPSFGGSPLNGSYLLNKANAQNDHSEGEGDKDFITRFKESLERNILNTITRGVANGEITDGTYDTGDFRIEVASVGGGVVLTITNLVTGEITVIEMPVYGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDH1</accession>
    <name>B1KDH1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0676</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323319.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84972">
        <property type="protein sequence ID" value="ACA84972"/>
        <property type="gene ID" value="Swoo_0676"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0676"/>
    <dbReference type="eggNOG" id="ENOG502ZDE1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2248941_0_0_6"/>
    <dbReference type="OrthoDB" id="2073446at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="12281" checksum="805B22FEDA6A70DA" modified="2008-04-29" version="1">MKEIEHWNKSNEVFGLQLPDGWFGRPGDNQHRLTYSLERENKLILELDNQLYLIFTKPLMIEKSGNDLVISNFKQLIFDYQGCGDMRSHNKPYGSGVVTLVSYNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDR3</accession>
    <name>B1KDR3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Outer membrane protein assembly factor BamC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bamC</name>
        <name evidence="7" type="ordered locus">Swoo_2178</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BamC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324804.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2178"/>
    <dbReference type="EnsemblBacteria" id="ACA86460">
        <property type="protein sequence ID" value="ACA86460"/>
        <property type="gene ID" value="Swoo_2178"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2178"/>
    <dbReference type="eggNOG" id="COG3317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063217_0_0_6"/>
    <dbReference type="OMA" id="YTVVWDR"/>
    <dbReference type="OrthoDB" id="1197067at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00924">
        <property type="entry name" value="OM_assembly_BamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014524">
        <property type="entry name" value="BamC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042268">
        <property type="entry name" value="BamC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010653">
        <property type="entry name" value="NlpB/DapX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06804">
        <property type="entry name" value="Lipoprotein_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026343">
        <property type="entry name" value="NlpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5 7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="371" mass="41918" checksum="9DCD0DEC733863A0" modified="2008-04-29" version="1" precursor="true">MLKQVTPLVLIAAVTACSSPVDRRQANDGDEYINAVVEPALIIPDGLNTPVYSKEYEIPSIGSKSDVKLVGKMLDIRPPLQVLPMAEGTHVEEGSDNIKIVVESIDNDIDLKKELYDVLQSYLASRSIAVLSEDYDNGLIETDWLESKEVIDSNLWGSDEVYLLRQRYQFHVDVRPHGRSGNISIDLIDHEESFDGEQQDIVLSGEDKRRYTIDMLNNAVAYMSVKRAQSIKAKRIKESLGIDVAVVKGSEPDVEAEEFVQSYWLADAPFKRTWERLRIVLPELGFEIIDMDIGKGLYYVNVNDDSGFWSSLWNEKDLPIDEGSYRLILKESGESTELYLHSADDQPLDNAVVEAVYEGLAELMREDRKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDW8</accession>
    <name>B1KDW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lytic murein transglycosylase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326302.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3710"/>
    <dbReference type="CAZy" id="GH103">
        <property type="family name" value="Glycoside Hydrolase Family 103"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87970">
        <property type="protein sequence ID" value="ACA87970"/>
        <property type="gene ID" value="Swoo_3710"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3710"/>
    <dbReference type="eggNOG" id="COG2951">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035402_1_1_6"/>
    <dbReference type="OMA" id="VMYAMAV"/>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011757">
        <property type="entry name" value="Lytic_transglycosylase_MltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043426">
        <property type="entry name" value="MltB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031304">
        <property type="entry name" value="SLT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163">
        <property type="entry name" value="PTHR30163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163:SF0">
        <property type="entry name" value="PTHR30163:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13406">
        <property type="entry name" value="SLT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02282">
        <property type="entry name" value="MltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764319" evidence="2">
        <location>
            <begin position="25"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="SLT_2" evidence="3">
        <location>
            <begin position="39"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="37791" checksum="1C2A2718BA49BDAE" modified="2008-04-29" version="1" precursor="true">MKIIPTLLATLLMGTLCATAPVSAQSDETIEQAADLLKSEFHDTQRASGFSDAEINSFLSSGQFNQSVIDAMTKPWEAKPWHQYYPIFLTEKRLQAGLKFWKEHEATVERAAKEFGVDPQIIIAIIGIETFYGGYMGNYPVVDALYTLGFYYPPRATFFRKELGNLQSLAKEEGLNIQELKGSYAGAMGYGQFIPSSYRHYAVDFDNDGQRDLLNNPVDAIGSVANYFHQHGWVAKAPVAIPLAETDGLPKPLKVWAGERLHYQVLDILSPSLALAESIDLDVSQPALIIELEQEAKSEYWLGLKNFYVITRYNRSPLYAMAVYQFSQQLKKAHDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE48</accession>
    <name>B1KE48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323381.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0739"/>
    <dbReference type="EnsemblBacteria" id="ACA85034">
        <property type="protein sequence ID" value="ACA85034"/>
        <property type="gene ID" value="Swoo_0739"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0739"/>
    <dbReference type="eggNOG" id="ENOG50318JU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1730134_0_0_6"/>
    <dbReference type="OMA" id="ANHRVTI"/>
    <dbReference type="OrthoDB" id="2100018at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="17331" checksum="8C9DECBA2F9CDE1B" modified="2008-04-29" version="1">MLFKEISSDRATIKNRRFNSISRKVIGIIFALITFILGLGLGRHDEIVILYWAIGALLSWHLLFAKVTVEIDLSKQVIATHVSSLYPIAKQVISITDIKAFNLSSDPTRVNRYNLLIVSNHNDKPFRFNFGSQADMNRLGQKLAHFCGKPFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE91</accession>
    <name>B1KE91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323424.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0782"/>
    <dbReference type="EnsemblBacteria" id="ACA85077">
        <property type="protein sequence ID" value="ACA85077"/>
        <property type="gene ID" value="Swoo_0782"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0782"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_14_2_6"/>
    <dbReference type="OMA" id="REYNAVY"/>
    <dbReference type="OrthoDB" id="1996723at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767285" evidence="1">
        <location>
            <begin position="22"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="24"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="19550" checksum="7B9F9CF76B052F7E" modified="2008-04-29" version="1" precursor="true">MKVFLKLILVLIFTSPLSAIASDLKVGDMAPNFKLQSTNGHFYQLSDYLGKQTLVLAWYPMANTHGCTLECRSLVQKGHLIREYNAVYMMASVDDLEDNQDFAEKQKADFPMLSDPTKETAKAYDVLNFVRVASRVTFYIGKDGKILKIDEDINAETAAEDIAATLKELGIEKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB8</accession>
    <name>B1KEB8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome B561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HupC/HyaC/HydC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324840.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2214"/>
    <dbReference type="EnsemblBacteria" id="ACA86496">
        <property type="protein sequence ID" value="ACA86496"/>
        <property type="gene ID" value="Swoo_2214"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2214"/>
    <dbReference type="eggNOG" id="COG3658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078451_2_1_6"/>
    <dbReference type="OMA" id="QYIGHNP"/>
    <dbReference type="OrthoDB" id="923657at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000516">
        <property type="entry name" value="Ni-dep_Hydgase_cyt-B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00161">
        <property type="entry name" value="NIHGNASECYTB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="5">
        <location>
            <begin position="16"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="247" mass="27821" checksum="CA3FFAB0AFAEDA4B" modified="2008-04-29" version="1">MKLTNEQGEELKTYRVWDRPSRIFHWVNLFLVVSLIFVGLLMLFRKDLGINALEAKIKLKELHVVIGYLFAGNLIFRILWGFIGSHFARFSHNIPSLKAIKEYKSALDRGENPQYIGHNPMGKLAVMVIMLMLVVLLATGLFRAGTDIYYPPFGGTISEYIAQDGVDAASIKPYDETGVDKAKLDEIKPYKSIAGKIHLYGAYFLILLIFIHVIAVIYAERKHQAGIISAMFSGKKRIVGKAKDSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE2</accession>
    <name>B1KEE2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324863.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2239"/>
    <dbReference type="EnsemblBacteria" id="ACA86520">
        <property type="protein sequence ID" value="ACA86520"/>
        <property type="gene ID" value="Swoo_2239"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2239"/>
    <dbReference type="eggNOG" id="COG2849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1703041_0_0_6"/>
    <dbReference type="OMA" id="ECINGVK"/>
    <dbReference type="OrthoDB" id="1997695at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17848" checksum="53473D04ACDCD512" modified="2008-04-29" version="1">MRLKWTIKRDREVVYTGTLKSMQLFTGMASLKETNGGLYGEGECINGVKVGPWCHYYKNGQKMSQMRFDADGLTHGESLLYHDNGVLWSRKMFDHGKLIELSQSFYDSGALESETHYDQKGRAKSIKEYFPSGELRHTMEFELGKLKHEQYYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEG6</accession>
    <name>B1KEG6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2263</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324887.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2263"/>
    <dbReference type="EnsemblBacteria" id="ACA86544">
        <property type="protein sequence ID" value="ACA86544"/>
        <property type="gene ID" value="Swoo_2263"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2263"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_0_6"/>
    <dbReference type="OMA" id="CANVPND"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766500" evidence="6">
        <location>
            <begin position="28"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="68"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="414"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1015" mass="112011" checksum="E1F0DFA8206289B8" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEJ3</accession>
    <name>B1KEJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent DNA helicase, RecQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2292</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324913.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2292"/>
    <dbReference type="EnsemblBacteria" id="ACA86571">
        <property type="protein sequence ID" value="ACA86571"/>
        <property type="gene ID" value="Swoo_2292"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2292"/>
    <dbReference type="eggNOG" id="COG0514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_9_2_6"/>
    <dbReference type="OMA" id="NERFRQF"/>
    <dbReference type="OrthoDB" id="54580at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="213"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="645" mass="72216" checksum="E43C53B6C35BC3E4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEL7</accession>
    <name>B1KEL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326364.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88032">
        <property type="protein sequence ID" value="ACA88032"/>
        <property type="gene ID" value="Swoo_3773"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3773"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="HENWIAI"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="37501" checksum="DE6F3FD86DFE4E3E" modified="2008-04-29" version="1">MPRPRRTQISIEDTPWYHCCSRVTRRAMLLGDDKFTGKNYDHRRDWVESQLLKLAGVFAIDVAAYAVMSNHLHVVLYIDIETVNRWSDRTVVEQWHKLFSGTEITQKFAKGEVIEEYQVAKLKHLVAIYRSRLCDISWFMRCLNEPIARKANIEDNCTGHFWEGRFKSQALLDEAAVLACMAYVELNPIRAKMVDTLENSDHTSIQLRVSAALKGEQPTKLLPFIGDELLNQPKGINFALKDYLELVDETGRVIRDDKRGSIAGNCTKILTRLNISSDNWIKLTSEFGELFHGPVGETQSLTRYCEHLQKRRRHFSKSCLHFQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ4</accession>
    <name>B1KEQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3810"/>
    <dbReference type="EnsemblBacteria" id="ACA88069">
        <property type="protein sequence ID" value="ACA88069"/>
        <property type="gene ID" value="Swoo_3810"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3810"/>
    <dbReference type="HOGENOM" id="CLU_3029928_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="55" mass="6160" checksum="B4DA7C7A3A7616CA" modified="2008-04-29" version="1">MDKNKIDHQQANDEKFELIEEQLLINVAGGRSASFCSEPCLPGFCYPELDLCISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF03</accession>
    <name>B1KF03_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323501.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0860"/>
    <dbReference type="EnsemblBacteria" id="ACA85154">
        <property type="protein sequence ID" value="ACA85154"/>
        <property type="gene ID" value="Swoo_0860"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0860"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_6"/>
    <dbReference type="OMA" id="PPYSLFW"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="39107" checksum="5B4B659021BBBC07" modified="2008-04-29" version="1">MEYRRLPHSNLEVSELCLGTMTWGEQNTQSEAFSQLDYAIGQGINFIDTAEMYPVPPKAETQGATERILGNYLKKAGNRDNLVIATKVAAPGGKGDYIRPNMALDWRNLHEAVDSSLERLQIDTIDLYQVHWPDRNTNFFGELSYQQIDENEKLTPIIDTLEALAALQKEGKIRYIGVSNETPWGLMKYLQLAEKHNLPRVVSVQNPYNLLNRSFEVGMAEISHREEVPLLAYSPLAFGALSGKYLDDQWPEGARLTLFKRFARYTGSQVALDATKAYVELAREFKLSPAQMSLAFVNSRKFVGSNIIGATNLEQLKENIDSINTSISPELMARLDELAQVYRLPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF90</accession>
    <name>B1KF90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324973.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2352"/>
    <dbReference type="EnsemblBacteria" id="ACA86631">
        <property type="protein sequence ID" value="ACA86631"/>
        <property type="gene ID" value="Swoo_2352"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2352"/>
    <dbReference type="eggNOG" id="ENOG502ZCFT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091612_0_0_6"/>
    <dbReference type="OMA" id="WIGTASQ"/>
    <dbReference type="OrthoDB" id="1411229at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22512" checksum="95F4D3C806A60C8E" modified="2008-04-29" version="1">MSSNIEITYINKSMNKDLPSIFVFTKNETPTFDALKEGVAWRVIPDIGRSSSSTFNFPIETSVGATWMDGQNTTQVLSSTIGKRYTVDKDDTGVVLAANGNASDTKSIEVNNNVNVPNGISAQLYKDGKLMLAKNIIGYNQKATFVLKPKLYWGVASEIQESQLLNSAVLNSDSFFEQDLEGVTKATVSLNGNAEDGYSFKIESQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFA2</accession>
    <name>B1KFA2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2364</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324985.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2364"/>
    <dbReference type="EnsemblBacteria" id="ACA86643">
        <property type="protein sequence ID" value="ACA86643"/>
        <property type="gene ID" value="Swoo_2364"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2364"/>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_749296_0_0_6"/>
    <dbReference type="OMA" id="FNLMRSH"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="3">
        <location>
            <begin position="13"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="4">
        <location>
            <begin position="219"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="414" mass="46565" checksum="3710F7CE7C588E49" modified="2008-04-29" version="1">MADLNSTLQESSNNQVDIEVMGDFFDDFKAAHQTCDSVLIELEDDPENDSLLNSLFRSIHTIKGNLIYVGLKDLTPLIQSLEDLLDAIRKKSIAYDSLLCDVILLTLDRTESMVLSRMDPDSEDLVFMLSDSDIDNLCVNISCIVDVPPENRIEYIRACLFVLDPDSHLEANDQFSSSTDKVIPNTGSEELLNSRELKINTDYLISNESVKHKEFDDVLKKYGVEIDEDIYFFKNLSTPLESRSFYWKGRTLRLLILSLAMNKCSGDRVNSSQLAVAVMMHDLGMSFLSRSSLTNTGAFSETEIVALHRHPGTSSLLLSEFENWGEAAQIVLQHHEQVDGAGYPNHLTGDKICDGAKIIAIADTFDARSHERAHHTLLKRPLVRTMNEINNFSGTQFDPYWVEIFNQVVGESKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK2</accession>
    <name>B1KFK2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3919</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326507.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3919"/>
    <dbReference type="EnsemblBacteria" id="ACA88177">
        <property type="protein sequence ID" value="ACA88177"/>
        <property type="gene ID" value="Swoo_3919"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3919"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_27_6"/>
    <dbReference type="OMA" id="KLDWPMS"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031930">
        <property type="entry name" value="HK_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038428">
        <property type="entry name" value="HK_sensor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16750">
        <property type="entry name" value="HK_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="173"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="236"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="448" mass="50361" checksum="A5ECB3BFD295DD16" modified="2008-04-29" version="1" precursor="true">MSRKLFWKLCLIIATGVVALFYVIGLLTSRTEEGMSLLAVEDRQTLTAWGKEAQALYLAGDEKKLALWLANLQREENTWAAVASYDVKHLAGGDLGDKFSQGYNLGRNVEWKVHLYFAANPTMEVPFTDQQVSFLIRLPERMRPGVYWRHTELTFQIILPTILLALLSFILYRHIMKPLLQLQLATRRFSKGKFDVRAKALMGERNDEFSDLAGAFDQMAVRIGEQIISQRQLIADLSHELRTPLTRLDIALGAVKERGEDENIERIDRESSHIRKLVEDTLTLAWLENEQPELQQESLELIDLLDVLIDDAKFEFPDREMVTQLPDSALVENSSHRAAGQALENILRNALRYTPSGKVVHVILTDLGDVFQIDILDQGPGVPDQFLSAIFKPFFRLDSSRGAEGSSFGLGLALAQRQLAAIRSSVTAQNRGEGEGSGLCMTIKIPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFP5</accession>
    <name>B1KFP5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323558.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0918"/>
    <dbReference type="EnsemblBacteria" id="ACA85211">
        <property type="protein sequence ID" value="ACA85211"/>
        <property type="gene ID" value="Swoo_0918"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0918"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023103_0_0_6"/>
    <dbReference type="OMA" id="ENWNIWR"/>
    <dbReference type="OrthoDB" id="1123871at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="725" mass="81705" checksum="57D0B371BBB7E269" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFU0</accession>
    <name>B1KFU0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoesterase</fullName>
            <ecNumber evidence="3">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0963</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323603.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0963"/>
    <dbReference type="EnsemblBacteria" id="ACA85256">
        <property type="protein sequence ID" value="ACA85256"/>
        <property type="gene ID" value="Swoo_0963"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0963"/>
    <dbReference type="eggNOG" id="COG0622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063749_1_1_6"/>
    <dbReference type="OMA" id="DILYHGP"/>
    <dbReference type="OrthoDB" id="1355703at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00841">
        <property type="entry name" value="MPP_YfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041802">
        <property type="entry name" value="MPP_YfcE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="PTHR11124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="4">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20285" checksum="692249ED49F61B53" modified="2008-04-29" version="1">MKLFFASDIHGCFESAQKMIKAFEQSGAQHLLLLGDILNHGPRNAIPQGYAPMKVVELLNCYADKIIAVRGNCDSEVDQMLLSFPMMADYNWVLLGDGRRLFLTHGHLYRSDNCPHLSAGDIIASGHTHLPVAEKQGEIILFNPGSVTIPRGENKPSYGLFEDNRLSVMNFDGDELSFYSLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV4</accession>
    <name>B1KFV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85270">
        <property type="protein sequence ID" value="ACA85270"/>
        <property type="gene ID" value="Swoo_0977"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0977"/>
    <dbReference type="eggNOG" id="ENOG50320H1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1776171_0_0_6"/>
    <dbReference type="OMA" id="TADKCAN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767323" evidence="1">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="146" mass="15699" checksum="02A640D2531D5548" modified="2008-04-29" version="1" precursor="true">MMKIIIWIAVAALVSGCAFVNTIDSVKQKGSKSEVYTSSSSQSLVSSQVGEFLSQCYKTSLVKMGGTTLGEVIHVDQYKIDGGTEYAVKKMLNNGYSHLLIVSVVAAAEDEKTEIVGYANDFTRAASFEQLDVIAKGGKPKCPYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGA9</accession>
    <name>B1KGA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pilin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326575.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3989"/>
    <dbReference type="EnsemblBacteria" id="ACA88246">
        <property type="protein sequence ID" value="ACA88246"/>
        <property type="gene ID" value="Swoo_3989"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3989"/>
    <dbReference type="eggNOG" id="COG4970">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098637_0_1_6"/>
    <dbReference type="OMA" id="NGWPAQH"/>
    <dbReference type="OrthoDB" id="1765531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20124" checksum="1ABD1594B12F9B60" modified="2008-04-29" version="1">MHYHSPPRALTQNAGFTLIELVVVIIILGILSVVALPKFINLSEDAHVSAVAGTGGAFKSGINLARSVWAVRVGSGPADDLPTFGDSESGELDFNDNGWPAQHWGTPDSDGDSPQLDNTEDCISVWETIFAGNEPSVSSSTSTDETDYKANYISPNQCRFDYRDNLNLSISYDSRNGSVVIDKDPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGH5</accession>
    <name>B1KGH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323650.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1010"/>
    <dbReference type="EnsemblBacteria" id="ACA85303">
        <property type="protein sequence ID" value="ACA85303"/>
        <property type="gene ID" value="Swoo_1010"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1010"/>
    <dbReference type="eggNOG" id="ENOG502ZW2E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150688_0_0_6"/>
    <dbReference type="OMA" id="AANICNY"/>
    <dbReference type="OrthoDB" id="1868784at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022193">
        <property type="entry name" value="DUF3718"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12514">
        <property type="entry name" value="DUF3718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766580" evidence="1">
        <location>
            <begin position="24"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="13575" checksum="5E46B5FFA625B913" modified="2008-04-29" version="1" precursor="true">MRLLPISIAAIIAASSYTLPAHANNQLAANICNYVQADDKNRLRKKLKENRVKLRNIYSSISCNGDSLLRTAFKSGSDKVGTFVAKRLSVSELQAAEADGTSISAWADANGHGASAINSAIKNRISGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL6</accession>
    <name>B1KGL6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Diguanylate phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1051</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323690.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1051"/>
    <dbReference type="EnsemblBacteria" id="ACA85344">
        <property type="protein sequence ID" value="ACA85344"/>
        <property type="gene ID" value="Swoo_1051"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1051"/>
    <dbReference type="eggNOG" id="COG1455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024302_1_0_6"/>
    <dbReference type="OMA" id="GYASFPH"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004501">
        <property type="entry name" value="PTS_EIIC_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51105">
        <property type="entry name" value="PTS_EIIC_TYPE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-3" evidence="10">
        <location>
            <begin position="1"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="9">
        <location>
            <begin position="418"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="671" mass="75602" checksum="F8E6F115811349C8" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGQ0</accession>
    <name>B1KGQ0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5655 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323724.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1085"/>
    <dbReference type="EnsemblBacteria" id="ACA85378">
        <property type="protein sequence ID" value="ACA85378"/>
        <property type="gene ID" value="Swoo_1085"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1085"/>
    <dbReference type="eggNOG" id="ENOG50307IZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101670_1_0_6"/>
    <dbReference type="OMA" id="NMPEKTG"/>
    <dbReference type="OrthoDB" id="1733947at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025629">
        <property type="entry name" value="DUF4287"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043714">
        <property type="entry name" value="DUF5655"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14117">
        <property type="entry name" value="DUF4287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18899">
        <property type="entry name" value="DUF5655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5655" evidence="1">
        <location>
            <begin position="72"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="180" mass="20224" checksum="F523EFC313747B85" modified="2008-04-29" version="1">MDKTLQTMINNMPEKTGKTLEEWFQILKKEKLEKHSIAVKFLKTEHGVTHGFANTIVTLSKEQDAPSEDLVSAQYDGKATLKPLYDKLISVVLKFGNDVTLSPKKASVSVIRAKQFALIKPATKSRVDLGLKLKDIEVQGRLENSGPFGTMCTHRIQLHELSDIDDEVIKWLSIAYEKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU5</accession>
    <name>B1KGU5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphogluconate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">edd</name>
        <name evidence="7" type="ordered locus">Swoo_2537</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17277"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="4.2.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; Entner-Doudoroff pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.12" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325155.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2537"/>
    <dbReference type="EnsemblBacteria" id="ACA86814">
        <property type="protein sequence ID" value="ACA86814"/>
        <property type="gene ID" value="Swoo_2537"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2537"/>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014271_1_2_6"/>
    <dbReference type="OMA" id="CANIAHV"/>
    <dbReference type="OrthoDB" id="193579at2"/>
    <dbReference type="UniPathway" id="UPA00226"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004456">
        <property type="term" value="F:phosphogluconate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046177">
        <property type="term" value="P:D-gluconate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009255">
        <property type="term" value="P:Entner-Doudoroff pathway through 6-phosphogluconate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02094">
        <property type="entry name" value="Edd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004786">
        <property type="entry name" value="6-phosphgluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43661:SF1">
        <property type="entry name" value="PTHR43661:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01196">
        <property type="entry name" value="edd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 6" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="608" mass="64586" checksum="43388EE6BEED5644" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU8</accession>
    <name>B1KGU8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, RpiR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325158.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2540"/>
    <dbReference type="EnsemblBacteria" id="ACA86817">
        <property type="protein sequence ID" value="ACA86817"/>
        <property type="gene ID" value="Swoo_2540"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2540"/>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055769_0_0_6"/>
    <dbReference type="OMA" id="VPFIHRS"/>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="121"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="284" mass="31332" checksum="CB7B703CC20CB9DF" modified="2008-04-29" version="1">MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPYVSRHVEEDDSPDSYTTKIFESSMASLDTARQSIDTAAINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVICFDDVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGITARYSPLSTECTLPVTMEVPEDTDMYLPMASRLAQLVVVDVLATGFTLRRGPRFRESLKRVKEVLKESRIDKDSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH20</accession>
    <name>B1KH20_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sulf_transp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4076</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326661.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4076"/>
    <dbReference type="EnsemblBacteria" id="ACA88332">
        <property type="protein sequence ID" value="ACA88332"/>
        <property type="gene ID" value="Swoo_4076"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4076"/>
    <dbReference type="eggNOG" id="COG2391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122700_1_0_6"/>
    <dbReference type="OMA" id="IDWANFT"/>
    <dbReference type="OrthoDB" id="1899767at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="8"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="14638" checksum="3B8CF3288180FC35" modified="2008-04-29" version="1" precursor="true">MSLLMSFLGGSLIGLAAIGLMIFNGRIAGISGILSSALLPKERASSDKETGLAWQWFFLFGLVSAGFVYALLSGSSSHNQPQFNQVSTPLLIIGGLLVGLGSNIGSGCTSGHGICGIGRLSPRSVIATGVFMLTGMLAAVLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH90</accession>
    <name>B1KH90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323744.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1105"/>
    <dbReference type="EnsemblBacteria" id="ACA85398">
        <property type="protein sequence ID" value="ACA85398"/>
        <property type="gene ID" value="Swoo_1105"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1105"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_5_1_6"/>
    <dbReference type="OMA" id="QTSARWQ"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="15762" checksum="C30CE1A7CBD16B0B" modified="2008-04-29" version="1">MTEHEGFTQLVLSIFRLNGLLVTEGDNLSQPVGLTSARWKILGAVEKSPQTVSQIARTMGQTRQSVQRIANELVKLEIVTFESNPEHKTAKLIVRTAKGAALFALLSESLIPWGHDAVEGISEEELLITLKVITKLIGRFEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF8</accession>
    <name>B1KHF8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1173</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323812.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1173"/>
    <dbReference type="EnsemblBacteria" id="ACA85466">
        <property type="protein sequence ID" value="ACA85466"/>
        <property type="gene ID" value="Swoo_1173"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1173"/>
    <dbReference type="eggNOG" id="COG2863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1884368_0_0_6"/>
    <dbReference type="OrthoDB" id="1939800at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764482" evidence="5">
        <location>
            <begin position="23"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="51"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="14729" checksum="E3D79258E1690100" modified="2008-04-29" version="1" precursor="true">MTLVLKASLLTAGLLLSSSTIAAAESPEVEFSQALAVTELKLDKTLLAQKFDLAQGEMLANTRCIACHGSAMLGMMPTYPSLMGQKTAYLFKQLIDFKQGDRTDPIMQAQAGMLSQAEMKNVAYYYSQQAPLSLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ5</accession>
    <name>B1KHJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase class-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325220.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2603"/>
    <dbReference type="EnsemblBacteria" id="ACA86880">
        <property type="protein sequence ID" value="ACA86880"/>
        <property type="gene ID" value="Swoo_2603"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2603"/>
    <dbReference type="eggNOG" id="COG0121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059273_0_0_6"/>
    <dbReference type="OMA" id="YWVFAHN"/>
    <dbReference type="OrthoDB" id="693464at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="28731" checksum="79F1176704921938" modified="2008-04-29" version="1">MCELLAMSANVPTDIVFSFTGLAQRGGVTGPHVDGWGITFYEGKGSRTFKDACPSSESHIAKLIQSYPIKSEVVVSHIRQANRGCVSLENTHPFTRELWGRYWTYAHNGQLSDYEDKFIVSRFQPVGDTDSEQAFCWILEEVVKKFGEQEPKELKPVFTFIAGLADEIRALGVFNMILSDGDHLMSYCSNNLCYITRKAPFGQAKLIDTDVVIDFKKETTPNDIVTVIATRPLTNNEEWNILGAGDWELFCKGEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV2</accession>
    <name>B1KHV2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4174</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326759.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4174"/>
    <dbReference type="EnsemblBacteria" id="ACA88430">
        <property type="protein sequence ID" value="ACA88430"/>
        <property type="gene ID" value="Swoo_4174"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4174"/>
    <dbReference type="eggNOG" id="COG0802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087829_2_2_6"/>
    <dbReference type="OMA" id="FTDDAIC"/>
    <dbReference type="OrthoDB" id="1827295at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="152" mass="16903" checksum="011BECF1F52444FF" modified="2008-04-29" version="1">MTSVKVYLDNEQDMVELGKRLAAIITPPLILNLSGELGAGKTTLSRGLIQAFGHQGAVKSPTYALVEPYELAGIDLFHFDLYRLSDPEELEFMGIRDYFTENSICIVEWPDRGHGLMPEADISCHIKYLDAGREVEIVSGSEKGQLLLSKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHW5</accession>
    <name>B1KHW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BFD domain protein (2Fe-2S)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326772.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4187"/>
    <dbReference type="EnsemblBacteria" id="ACA88443">
        <property type="protein sequence ID" value="ACA88443"/>
        <property type="gene ID" value="Swoo_4187"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4187"/>
    <dbReference type="eggNOG" id="COG2906">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159205_3_4_6"/>
    <dbReference type="OMA" id="MYVCLCE"/>
    <dbReference type="OrthoDB" id="1969696at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer2_BFD" evidence="1">
        <location>
            <begin position="2"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="63" mass="7018" checksum="F60BEAA68296C9A6" modified="2008-04-29" version="1">MYVCLCHAVTDTQIKEAVSQGDISLNDVKKRLGVGDQCGKCVKMATQIIQRQLDVEPNYYEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY3</accession>
    <name>B1KHY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326790.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4205"/>
    <dbReference type="EnsemblBacteria" id="ACA88461">
        <property type="protein sequence ID" value="ACA88461"/>
        <property type="gene ID" value="Swoo_4205"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4205"/>
    <dbReference type="eggNOG" id="COG4775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_705850_0_0_6"/>
    <dbReference type="OMA" id="VPWWQWV"/>
    <dbReference type="OrthoDB" id="364966at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764508" evidence="2">
        <location>
            <begin position="26"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="440" mass="49347" checksum="8A8F86EA24EF67F4" modified="2008-04-29" version="1" precursor="true">MLKKILNYQVILALYCAFNLSSTKAAESDSPTAGSVLDPIVEIEQTSSQYDEKREYKADFEAVPFIFSTETLSTTVGGAGVLKHAGQVQASLLGIGLYSKNDSWLTYLGAYNYQLPSLERWLFSAEYYRASYKQGIYFVPNGEEPHHNVGLPTDKVVTVGDETYAKLHLKYVLPWGRGSQGAARSLLAKGGAISWDPRESGVSSITLTPFIQTQDLTGFDDLPTKAQGLKLKLDWDNRDNGKNSHSGGRTSFTLSRDFGGDSGRNADDRQSWTTWEFEQSAFLSIGNNSWFEQQTLALNLYLADTPTWNDGDYITGEYHRPPAFAGISLGGFDSLRGYSSDEFVGRSAVLYSAEYRVQPKWQPLQSLPVFNLYNVPWWQWVVFAETGQVSDKFSFNELHQDMKWTLGAGVRFEVESVVVRTEFAYSGEESQFWVMVNQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA5</accession>
    <name>B1KIA5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Periplasmic nitrate reductase</fullName>
            <ecNumber evidence="12">1.9.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">napA</name>
        <name evidence="16" type="ordered locus">Swoo_2680</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(II)-[cytochrome] + 2 H(+) + nitrate = 2 Fe(III)-[cytochrome] + H2O + nitrite</text>
            <dbReference type="Rhea" id="RHEA:12909"/>
            <dbReference type="Rhea" id="RHEA-COMP:11777"/>
            <dbReference type="Rhea" id="RHEA-COMP:11778"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.9.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
        <text evidence="12">Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.9.6.1" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2680"/>
    <dbReference type="EnsemblBacteria" id="ACA86956">
        <property type="protein sequence ID" value="ACA86956"/>
        <property type="gene ID" value="Swoo_2680"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2680"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_13_4_6"/>
    <dbReference type="OMA" id="GMNAHQH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050140">
        <property type="term" value="F:nitrate reductase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02791">
        <property type="entry name" value="MopB_CT_Nitrate-R-NapA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01630">
        <property type="entry name" value="Nitrate_reduct_NapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041957">
        <property type="entry name" value="CT_Nitrate-R-NapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010051">
        <property type="entry name" value="Periplasm_NO3_reductase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01706">
        <property type="entry name" value="NAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11 12" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 12" id="KW-0574">Periplasm</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12 14" id="KW-0732">Signal</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008947924" description="Periplasmic nitrate reductase" evidence="14">
        <location>
            <begin position="30"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="15">
        <location>
            <begin position="41"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="12">
        <location>
            <begin position="214"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="12">
        <location>
            <begin position="245"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="12">
        <location>
            <begin position="511"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="12">
        <location>
            <begin position="721"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="534"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="561"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="797"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="805"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="822"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA86956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="831" mass="93356" checksum="325801614EA6B2C6" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB5</accession>
    <name>NHAB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Na(+)/H(+) antiporter NhaB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sodium/proton antiporter NhaB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nhaB</name>
        <name type="ordered locus">Swoo_2690</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 H(+)(out) + 2 Na(+)(in) = 3 H(+)(in) + 2 Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29247"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:29248"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325306.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIB5"/>
    <dbReference type="SMR" id="B1KIB5"/>
    <dbReference type="STRING" id="392500.Swoo_2690"/>
    <dbReference type="EnsemblBacteria" id="ACA86966">
        <property type="protein sequence ID" value="ACA86966"/>
        <property type="gene ID" value="Swoo_2690"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2690"/>
    <dbReference type="eggNOG" id="COG3067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041110_0_0_6"/>
    <dbReference type="OMA" id="QFEMLAV"/>
    <dbReference type="OrthoDB" id="305652at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01599">
        <property type="entry name" value="NhaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004671">
        <property type="entry name" value="Na+/H+_antiporter_NhaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302:SF1">
        <property type="entry name" value="PTHR43302:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06450">
        <property type="entry name" value="NhaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00774">
        <property type="entry name" value="NhaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0050">Antiport</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0915">Sodium</keyword>
    <keyword id="KW-0739">Sodium transport</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000191546" description="Na(+)/H(+) antiporter NhaB">
        <location>
            <begin position="1"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01599"/>
        </source>
    </evidence>
    <sequence length="528" mass="57829" checksum="106BEB3E0B634A20" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC4</accession>
    <name>B1KIC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-dependent Clp protease, ATP-binding subunit clpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2699</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325313.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2699"/>
    <dbReference type="EnsemblBacteria" id="ACA86975">
        <property type="protein sequence ID" value="ACA86975"/>
        <property type="gene ID" value="Swoo_2699"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2699"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_2_6"/>
    <dbReference type="OMA" id="GRVIQEH"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013461">
        <property type="entry name" value="ClpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02639">
        <property type="entry name" value="ClpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="9">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="752" mass="83253" checksum="9493E7D95B81B6FF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIG1</accession>
    <name>B1KIG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prolyl oligopeptidase</fullName>
            <ecNumber evidence="5">3.4.21.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2736</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.26" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325349.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2736"/>
    <dbReference type="EnsemblBacteria" id="ACA87012">
        <property type="protein sequence ID" value="ACA87012"/>
        <property type="gene ID" value="Swoo_2736"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2736"/>
    <dbReference type="eggNOG" id="COG1505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011290_1_1_6"/>
    <dbReference type="OMA" id="ACMTQRP"/>
    <dbReference type="OrthoDB" id="315644at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9_N" evidence="4">
        <location>
            <begin position="41"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="493"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="714" mass="79574" checksum="EBCA33754582420C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIH2</accession>
    <name>B1KIH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2747</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325359.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2747"/>
    <dbReference type="EnsemblBacteria" id="ACA87023">
        <property type="protein sequence ID" value="ACA87023"/>
        <property type="gene ID" value="Swoo_2747"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2747"/>
    <dbReference type="eggNOG" id="COG2234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019932_2_1_6"/>
    <dbReference type="OMA" id="VANINMD"/>
    <dbReference type="OrthoDB" id="1465483at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764915" evidence="2">
        <location>
            <begin position="21"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="3">
        <location>
            <begin position="138"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="4">
        <location>
            <begin position="305"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="556" mass="61209" checksum="856C34883174D012" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK1</accession>
    <name>B1KIK1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sigma 54 modulation protein/ribosomal protein S30EA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326824.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4241"/>
    <dbReference type="EnsemblBacteria" id="ACA88497">
        <property type="protein sequence ID" value="ACA88497"/>
        <property type="gene ID" value="Swoo_4241"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4241"/>
    <dbReference type="eggNOG" id="COG1544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071472_3_1_6"/>
    <dbReference type="OMA" id="NLTGHHI"/>
    <dbReference type="OrthoDB" id="2088581at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="95" mass="11014" checksum="FCA2F17C5B736153" modified="2008-04-29" version="1">MQINVTGHHIEITTSLRQYIEEKFSKLERHFDQINNVHVILNVQKMQQKAEAKLHLAGGEVFAASQHADMYAAIDSLIDKLDRQVIKHKEKQTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU7</accession>
    <name>B1KIU7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1303</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323941.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1303"/>
    <dbReference type="EnsemblBacteria" id="ACA85595">
        <property type="protein sequence ID" value="ACA85595"/>
        <property type="gene ID" value="Swoo_1303"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1303"/>
    <dbReference type="eggNOG" id="COG0347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082268_0_0_6"/>
    <dbReference type="OMA" id="HQIEVNF"/>
    <dbReference type="OrthoDB" id="2021322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="3">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12606" checksum="909977D98FBB7B2D" modified="2008-04-29" version="1">MKKVEAIIKPFKLDDVRESLAEIGITGMTVSEVKGFGRQKGHTELYRGAEYMVDFLPKVKIELVIQDELLDQALEVIVDTARTGKIGDGKIFVTEIERVIRIRTGEENEEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV3</accession>
    <name>B1KIV3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly protein PilM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323947.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1309"/>
    <dbReference type="EnsemblBacteria" id="ACA85601">
        <property type="protein sequence ID" value="ACA85601"/>
        <property type="gene ID" value="Swoo_1309"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1309"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066015_1_0_6"/>
    <dbReference type="OMA" id="GDFFPRS"/>
    <dbReference type="OrthoDB" id="1643157at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764535" evidence="1">
        <location>
            <begin position="27"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="291" mass="33717" checksum="A7C7930C2F3193D1" modified="2008-04-29" version="1" precursor="true">MRFMLRLRIKLLLISLLSVFCLTPNAYSETLVTTIPQSWQLNLLKEALSRVETQYDISMLDTEMNQKRKVEEALAGSIDIFWSMTSQQLEAVVLPVRIPIFKGLLGNRLLIIRSDEQQRFIDVKSRDDFLQFYAGQNRYWPDALILEENGLPLITSYKYKNLYPMLEGGRFDYLALGAQEIWQELDKNPDPNLKVDSAILLQYRSPAYFFISPEKPLLAKDLKKGLESMIADGSFDQLFNKELEIDALYEQAQFSKRRIIRLQTPGLSSLTPVTRDELWLDLFNMEGKGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL3</accession>
    <name>B1KJL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Conserved repeat domain protein</fullName>
            <ecNumber evidence="10">1.3.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1394</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.74" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324032.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1394"/>
    <dbReference type="EnsemblBacteria" id="ACA85686">
        <property type="protein sequence ID" value="ACA85686"/>
        <property type="gene ID" value="Swoo_1394"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1394"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_281153_0_0_6"/>
    <dbReference type="OMA" id="SNIMLME"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04852">
        <property type="entry name" value="Peptidases_S8_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034197">
        <property type="entry name" value="Peptidases_S8_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017312">
        <property type="entry name" value="Subtilisin_Alteromonadales"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PTHR10795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037898">
        <property type="entry name" value="Subtilisin_rel_Sputw3181_3341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764968" evidence="6">
        <location>
            <begin position="23"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="56"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="187"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="432"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1109" mass="114256" checksum="CDF655437518FA4D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ8</accession>
    <name>B1KJQ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1439</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324077.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1439"/>
    <dbReference type="EnsemblBacteria" id="ACA85731">
        <property type="protein sequence ID" value="ACA85731"/>
        <property type="gene ID" value="Swoo_1439"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1439"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035565_0_0_6"/>
    <dbReference type="OMA" id="MVGFKAN"/>
    <dbReference type="OrthoDB" id="883339at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="208"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="475" mass="52159" checksum="B00046BAD3FABB9A" modified="2008-04-29" version="1">MQTLEQLKSGQLKGATRLQLAENLSLFPTEIFELADSLEVLDLSNNQLDSLPDDFGCLKKLKILFLSNNRFTQLPKVIANCPKLEMIGFKANQIVSVAEDSLPKHTRWLILTDNKLERLPNSIGELYRLQKLALAGNCLTALPDTMANCHSLELARLSANQFTSLPDWLFQLPKLSWLAVAGNPLFAEGYKTGLTENKSVGHVNLSDIELGEQIGEGASGVIYRARWLAQPRWLHGESLDIAVKLFKGEVTSDGYPSDELANCLQAGEHQNLIKVVAQIDDGGQLGLVMDLIPSSFGNLGLPPSLISCTRDTFPAGTEFGLSTIINVGKQMAETMTHLHQNGVSHGDLYAHNTMLNKHMLNKNALNTDPVSISKSDETLFGDFGAASNLHLLPRLQAEAMESIEVRAFGCLLDDMLNQVSQQVSRTADKAIFNELIELSQACMQVQLPIRPRFNELSSALKALQYKVQGLADVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJY4</accession>
    <name>B1KJY4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arylesterase</fullName>
            <ecNumber evidence="2">3.1.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325507.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2898"/>
    <dbReference type="EnsemblBacteria" id="ACA87171">
        <property type="protein sequence ID" value="ACA87171"/>
        <property type="gene ID" value="Swoo_2898"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2898"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051180_3_0_6"/>
    <dbReference type="OMA" id="MRIPPNY"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004064">
        <property type="term" value="F:arylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="20"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="20747" checksum="C1EA126301D7294A" modified="2008-04-29" version="1">MSLAAILSCSQVIAAPILILGDSLSASYGVDEDQGWVNLMRKKMPQHEIVNGSVSGETTAGGLRRLPALLDSVKPELVLVELGGNDGLRGFTPQQLKENLTKIITLTKAQGSQLLLSEIMVPPNYGPRYAKMFNQVYADLAAEHQITLMPFFMTKIAINPDFMQRDGIHPNASAQNDIAEFVVPWIEKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK16</accession>
    <name>B1KK16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325539.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2930"/>
    <dbReference type="EnsemblBacteria" id="ACA87203">
        <property type="protein sequence ID" value="ACA87203"/>
        <property type="gene ID" value="Swoo_2930"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2930"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008878_4_0_6"/>
    <dbReference type="OMA" id="MAPYPST"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="1">
        <location>
            <begin position="16"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="2">
        <location>
            <begin position="395"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="527" mass="57071" checksum="BAF16A45EF98F815" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK26</accession>
    <name>B1KK26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylation site containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326983.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4405"/>
    <dbReference type="EnsemblBacteria" id="ACA88657">
        <property type="protein sequence ID" value="ACA88657"/>
        <property type="gene ID" value="Swoo_4405"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4405"/>
    <dbReference type="eggNOG" id="COG4968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080973_1_0_6"/>
    <dbReference type="OMA" id="FQYQHQV"/>
    <dbReference type="OrthoDB" id="1497438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="277" mass="30306" checksum="2B72E832553665F0" modified="2008-04-29" version="1">MASHKNNKSYKHHKSAQGFTLVEMVTVIIVLGVLVLGVSSFVVLGTRIFVESTSVEQVLSQSRFAMERMTRELRNAVPNSIRLTPDTVLTYQCVEFVPIQASASYVDLPISPAAANNTGTVFPPSQGLNVGNQMLVYPLLPKHIYSATPAGTTGRLFDVDAFDASTGEITFDNSIQFAEASPIKRYFMISGAVSYCFQSGGELRRYANYGINANQLTPNSSGVLMAENVVNNLATDKPILLAPSSLVNNAILQLRPKFEVVNQKFQYQHQVQVINVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK64</accession>
    <name>B1KK64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327021.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88695">
        <property type="protein sequence ID" value="ACA88695"/>
        <property type="gene ID" value="Swoo_4443"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4443"/>
    <dbReference type="eggNOG" id="ENOG502ZE1A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126008_0_0_6"/>
    <dbReference type="OMA" id="RTIYEWQ"/>
    <dbReference type="OrthoDB" id="1964551at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="167" mass="19651" checksum="9E51C068989F8A65" modified="2008-04-29" version="1" precursor="true">MSRLSGLGQVIVFSALLTLPSLSVQANDRFNWSSNVWVQPSWSSSWGNHYPNYSSGWRWGLGVGTGSPYWNNHSYYWNRPWYRPYWRNNWGYPYRYRDNYRNTYTKPAVPKVISAPEQVTTSVQFASGLKSLPANARAIQKNGHTIYQWQGVEYQFDWESETYREVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK81</accession>
    <name>B1KK81_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4460</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327038.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88712">
        <property type="protein sequence ID" value="ACA88712"/>
        <property type="gene ID" value="Swoo_4460"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4460"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_6_0_6"/>
    <dbReference type="OMA" id="MYHHIIN"/>
    <dbReference type="OrthoDB" id="881796at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="27913" checksum="322ADD6E3FA97CCC" modified="2008-04-29" version="1">MSELLLLILYCALLGSIVGFLAGLLGIGGGLIIVPVLSAILLHFEVLPPEQVVVAAIATSLASILFTSTSSAIAHHKNGNVPWEIAPWIMTGVGLGALISGFMAALLPEQIVRLVFAVCVLLIALKMFYSSTKTDTATTRKMPNKGLLTLFTTITGGLSAMIGIGGGALLVPLLTYFSIDMKKAIGCASACGIVIALFGSIGYISSGSAHFSLADGFAGFVYLPALLGIVCTSWFTAPLGAKATAHLPVPLIKKIFAGLLLAIAVNMYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP6</accession>
    <name>B1KKP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325599.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87263">
        <property type="protein sequence ID" value="ACA87263"/>
        <property type="gene ID" value="Swoo_2992"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2992"/>
    <dbReference type="eggNOG" id="COG3360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161196_1_1_6"/>
    <dbReference type="OMA" id="HYQVGLK"/>
    <dbReference type="OrthoDB" id="2025589at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009923">
        <property type="entry name" value="Dodecin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025543">
        <property type="entry name" value="Dodecin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036694">
        <property type="entry name" value="Dodecin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39324">
        <property type="entry name" value="PTHR39324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07311">
        <property type="entry name" value="Dodecin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89807">
        <property type="entry name" value="SSF89807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="69" mass="7663" checksum="9B6FCFB50C8CEC3C" modified="2008-04-29" version="1">MSHTYKIIELVGSSPISSDDAIKEAINTAGQTLKHLRWFEVVETRGHLEAGVVAHWQVTIKVGFTLEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKT4</accession>
    <name>B1KKT4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325637.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3030"/>
    <dbReference type="EnsemblBacteria" id="ACA87301">
        <property type="protein sequence ID" value="ACA87301"/>
        <property type="gene ID" value="Swoo_3030"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3030"/>
    <dbReference type="eggNOG" id="ENOG50331W9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113195_0_2_6"/>
    <dbReference type="OMA" id="PLDWGWW"/>
    <dbReference type="OrthoDB" id="2040370at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025489">
        <property type="entry name" value="DUF4381"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14316">
        <property type="entry name" value="DUF4381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="19999" checksum="073D6FB906D9A877" modified="2008-04-29" version="1">MQAAATNPALQALKDIHTPAVVESWPIAPGYWLILLVSVSTLLFTVIWLKRRIQRSAAKRAALMELERLDIHNTNICVEINTLIKRAALSYLPREDVAGLEGQAWYAWINSQVKQPLLELEKLLDRRYQREPLTPDEAQRLKQITASWLKEALPLTQQKSAQSPLSHKQEQELKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY2</accession>
    <name>B1KKY2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
            <ecNumber evidence="7">6.3.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="12" type="ordered locus">Swoo_4538</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4538"/>
    <dbReference type="EnsemblBacteria" id="ACA88788">
        <property type="protein sequence ID" value="ACA88788"/>
        <property type="gene ID" value="Swoo_4538"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4538"/>
    <dbReference type="eggNOG" id="COG0769">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022291_3_2_6"/>
    <dbReference type="OMA" id="CFMEVSS"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="110"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="337"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="41"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="154"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="112"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="502" mass="54057" checksum="B3C4EB55722A1B50" modified="2008-04-29" version="1">MLLKDLLAPWFHYSGSESVNKLSLDSREVDQGDLFVAVPGHQVDGRDYIDVAAKNGAQVSLVHTDNPEMHGKVLTSNSTQIFFFQLSRQLSALAAQAYPLPVERLKLVGVTGTNGKTSITQLMAQLLVCLGKQPAVMGTLGNGLWGGLVDSGNTTADPITIMAQLNAFNELGADLCAMEVSSHGLIQARVDAVPFDLAIFTNLSRDHLDYHGTMQAYGEAKFRLFKFPSLKSGVINLDDDLGKQWLAQSDSAKLIGYSIAGDSDTVSQDAAIYTKGNHFHNQGVRAKLVWPEGCGNIDSPLLGAFNLSNLLAALAGLYQLGFDMNALLNAVPKLNAVAGRMEQFTTENGITLVVDYAHTPDAIEQALKALRGHCEGELWCLFGCGGDRDKGKRPLMAQSAEAYADRIMVTSDNARSESPDEIINDVLAGLNRPERAVTQVDRELAIREVLAAAKPGDLILLAGKGHETYQEAGGVRRDYDERALARSLASGSLANNSSEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL14</accession>
    <name>B1KL14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327145.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4570"/>
    <dbReference type="EnsemblBacteria" id="ACA88820">
        <property type="protein sequence ID" value="ACA88820"/>
        <property type="gene ID" value="Swoo_4570"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4570"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_47_4_6"/>
    <dbReference type="OMA" id="IDAAQNH"/>
    <dbReference type="OrthoDB" id="1914633at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="82" mass="9134" checksum="5D81E9E3491067AC" modified="2008-04-29" version="1">MVTQLNPNTLGKRIKDRRKAANMTQEVAASFCGVTKKTLIRVEKGEDVYFSTIVKILNGLGIKLTFDTPNSENKLGGSNEWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL45</accession>
    <name>B1KL45_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322735.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0085"/>
    <dbReference type="EnsemblBacteria" id="ACA84386">
        <property type="protein sequence ID" value="ACA84386"/>
        <property type="gene ID" value="Swoo_0085"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0085"/>
    <dbReference type="eggNOG" id="COG1122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="PGVVRWK"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="26605" checksum="5352F7AADDFE269D" modified="2008-04-29" version="1">MVKVIAQNIEMRFGERRLFAVERIQLSQGQTVHLQGDNGSGKTTLMKMLAGLIAPTKGQITTQGFAPLPWWRSNSLLGKAVYLHQHPYLFDGSVEYNLRYPHPFCTISKQLIEQRTQDAIEKAGLTHLTKQAASSLSGGERQRLAIARAWIMQPKLLMLDEPTSNMDTYSQELVLAMVKDLQQLGTGMLVSSHQSCALTSLCDQNWRIENQGISSSINDASCATSPQTTLQEPRYVIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL60</accession>
    <name>B1KL60_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322750.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0100"/>
    <dbReference type="EnsemblBacteria" id="ACA84401">
        <property type="protein sequence ID" value="ACA84401"/>
        <property type="gene ID" value="Swoo_0100"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0100"/>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_1_6"/>
    <dbReference type="OMA" id="SKDVCLM"/>
    <dbReference type="OrthoDB" id="1094814at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021812">
        <property type="entry name" value="DUF3391"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11871">
        <property type="entry name" value="DUF3391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="133"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="43493" checksum="E6D53B3D90F5C37D" modified="2008-04-29" version="1">MVESVESKAHVKFPVSKLSVGMFVTSIDNDGQVAITNAGQIKDREAINKLIKNGIKYVWVDKERSADSCGFKNTVQPPPTVKKKAPSREASQQKAKKLVTEAKDLLAKVLSETFEGKAIEVAPFEEFADNLIDSALLDSDALKCVSALRTKDAYLLEHSVNVAFLLITFGQHLNLDKQKLKEMAVGGILHDVGKIQVDDKVLHKPGKLSQEEFEHMKKHQNFAMNIMSKTDGISQISKDVCLMHHEKLDGNGYPNGLKGEELPLHGRMSCIVDIYDALTAKRCYKDAMSPAAAFKVLLSLTPFHLDEALVYQFIRSVGVYPVGSLVELSDGRIGIVWHAKGRDALHPILKCFYSIKHKRYLDVTFVDLLKSDANIERGISPCSLDVDPAPFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL69</accession>
    <name>B1KL69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Asp/Glu/hydantoin racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322759.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0109"/>
    <dbReference type="EnsemblBacteria" id="ACA84410">
        <property type="protein sequence ID" value="ACA84410"/>
        <property type="gene ID" value="Swoo_0109"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0109"/>
    <dbReference type="eggNOG" id="COG3473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068086_3_0_6"/>
    <dbReference type="OMA" id="NTTMEME"/>
    <dbReference type="OrthoDB" id="1739382at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026286">
        <property type="entry name" value="MaiA/AMDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40267">
        <property type="entry name" value="PTHR40267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17645">
        <property type="entry name" value="Amdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015736">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="259" mass="28325" checksum="33A535311223DEAB" modified="2008-04-29" version="1">MMSFEAFTSFEQPLEHQQAPRINRVHIGLVQLSTDHSLEMDWAKLLGTQAGVFSSRVYYSSEMTPEALDQIANGIVEASDLIATGLPMDVMAFGCTSASIIIGEEKVAGLLTQNRGDIPATNPWTAAKASFKHLNAKKIAVFSPYPTSVNYPLYQQLTDADFDVVTLGSLGIERDTDITLVSKESMFAALELMLKDSDAELVFMSCTNLRVLDYIEEIEAKFGIPVVCSNSAMFWHAMHLTGKAAICPGYGKLLNNQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE9</accession>
    <name>B1KLE9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1588</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324220.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1588"/>
    <dbReference type="EnsemblBacteria" id="ACA85874">
        <property type="protein sequence ID" value="ACA85874"/>
        <property type="gene ID" value="Swoo_1588"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1588"/>
    <dbReference type="eggNOG" id="ENOG502ZAC4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057852_0_0_6"/>
    <dbReference type="OMA" id="WPFAKTS"/>
    <dbReference type="OrthoDB" id="969942at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1660.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032388">
        <property type="entry name" value="FlgT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038165">
        <property type="entry name" value="FlgT_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032386">
        <property type="entry name" value="FlgT_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032370">
        <property type="entry name" value="FlgT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038180">
        <property type="entry name" value="FlgT_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16538">
        <property type="entry name" value="FlgT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16539">
        <property type="entry name" value="FlgT_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16548">
        <property type="entry name" value="FlgT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764633" evidence="1">
        <location>
            <begin position="22"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="FlgT_N" evidence="4">
        <location>
            <begin position="22"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="FlgT_M" evidence="3">
        <location>
            <begin position="116"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="FlgT_C" evidence="2">
        <location>
            <begin position="312"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="43142" checksum="3155C2B8726C6435" modified="2008-04-29" version="1" precursor="true">MKFVTLLLLTLISLYSHLAVAAWVVVKGESNIVDGNVTKAREDAIHQALTYATLQNGASFTSTQTVNNGQLTQDSFSLQKQSQAAKVELINELIEGNKLTVMVKVDVIGASAHQAQCDSQSLKAAILVPQSMIRDRAQLRYGNIGAFEKALSVRIGNALTQSSNSSFSHIHANERLDIEQALVDIRGYRLPSWLSEITDSQYVLLPEIIDISTNPAESNMLGLWSSDPIRQFQLRLSLYHGISGEQIWSQDFTSSAPWEFERQETVPSNQNRFWNSAYGKDIDKVLAQAVQEIDTSLTCRPILGQVVAKQHDRVIINLGRRHGIRVGDTFQLVLQENMPDRFDKMRAVASESKATIKIDQVTQDTATAMLVNQKAAYNVQINDIAIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLJ7</accession>
    <name>B1KLJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324268.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1636"/>
    <dbReference type="EnsemblBacteria" id="ACA85922">
        <property type="protein sequence ID" value="ACA85922"/>
        <property type="gene ID" value="Swoo_1636"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1636"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_12_6"/>
    <dbReference type="OMA" id="AAGAHEY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="14187" checksum="85EF2BFD2B83CB1A" modified="2008-04-29" version="1">MDKNMKILVVDDFSTMRRIIKNLLRDLGFNNTQEADDGSTALPMLQKGDFDFVVTDWNMPGMQGIDLLKAIRADDELKNIPVLMVTAEAKREQIIAAAQAGVNGYVVKPFTAATLKEKLDKIFERLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLL1</accession>
    <name>B1KLL1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane protein involved in aromatic hydrocarbon degradation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3037</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3037"/>
    <dbReference type="EnsemblBacteria" id="ACA87308">
        <property type="protein sequence ID" value="ACA87308"/>
        <property type="gene ID" value="Swoo_3037"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3037"/>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035981_0_0_6"/>
    <dbReference type="OMA" id="WDDSWLF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767187" evidence="8">
        <location>
            <begin position="24"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="441" mass="47169" checksum="30FEB98FA0010C99" modified="2008-04-29" version="1" precursor="true">MMKYFNKTILAVAVTLASSQAIAAGFQLNSQSATGLGRAFAGDAVIADNASVLSRNPAAMALFDEKSLSVGAAYADLDVNISDVSTPLGNYGSAEGVAESKLIPNFYYIQPINDKWAFGVAGFSNFGTGTDLTSLANSNPTMDNGTVVPAPAPVDLLGNTEIVTMNFNASLSYRFNEHFSVGAGVDIIYGEGNLSREGNLPFDDNGSMVPVSLVDVEADGIAFGGILGAVYEFNADHRLGMSYRFSPEFKATGDVNMTQPGVGTIAFDEINIPMPDIFQVAGFHQLTEKFALHYTAQLTTWGDFHEITVTDGQLANGTAAGDAVLKQYAWEDSWLFSVGGTYTINENWKVRAGYMHDQGVVGDVSSLSIPDSDRNWYTAGVSYNLSTQSTIDMGIAFVRGEDVHVTENSSVIASIPGLNGDVTAYTRSDAIYYSVQYSYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLU6</accession>
    <name>B1KLU6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ferrous iron transport protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_3122</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Probable transporter of a GTP-driven Fe(2+) uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325729.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3122"/>
    <dbReference type="EnsemblBacteria" id="ACA87393">
        <property type="protein sequence ID" value="ACA87393"/>
        <property type="gene ID" value="Swoo_3122"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3122"/>
    <dbReference type="eggNOG" id="COG0370">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013350_3_0_6"/>
    <dbReference type="OMA" id="MEMPDYE"/>
    <dbReference type="OrthoDB" id="304844at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003373">
        <property type="entry name" value="Fe2_transport_prot-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00437">
        <property type="entry name" value="feoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="4 12" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="667"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="695"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="727"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="13">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="764" mass="81257" checksum="8EF2610038A0EA0D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLZ0</accession>
    <name>B1KLZ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327195.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4620"/>
    <dbReference type="EnsemblBacteria" id="ACA88870">
        <property type="protein sequence ID" value="ACA88870"/>
        <property type="gene ID" value="Swoo_4620"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4620"/>
    <dbReference type="eggNOG" id="ENOG502ZBMT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1265460_0_0_6"/>
    <dbReference type="OMA" id="CQSAYYA"/>
    <dbReference type="OrthoDB" id="1502743at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021342">
        <property type="entry name" value="DUF2959"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043473">
        <property type="entry name" value="S2_sf_CoV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11172">
        <property type="entry name" value="DUF2959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111474">
        <property type="entry name" value="SSF111474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767478" evidence="2">
        <location>
            <begin position="23"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="42"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="215" mass="24139" checksum="FDE65F507CF66FB5" modified="2008-04-29" version="1" precursor="true">MKKHILMAIVSTSLLLSGCQSAYYGAMEKVGYHKRDIMVDRVTDAKESQEEAQEQFSSALEEMQALLNHDGGDLEKAYNKAKDEYESSQDAADDVSNRIEKVEDVADALFDEWQTEIGEISKASLRRNSESKLRETKRSYEQLVRTMKRAEGKMAPVLTAMKDNMLYLKHNLNAQAIGAIKGEFASLQTDITGLIKEMNKSIDESTKFIASIEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM84</accession>
    <name>B1KM84_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322846.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84497">
        <property type="protein sequence ID" value="ACA84497"/>
        <property type="gene ID" value="Swoo_0196"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0196"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="HHIALYR"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="37572" checksum="4567AF4AE4981F7A" modified="2008-04-29" version="1">MPRPRRSQISLEDTPMYHCCSRVTRRAFLFGDDELTGKNYDHRRDWVESQLLKLAVVFAIDIAAYAVMSNHLHLVLRVDIYEANAWSDREVVEHWHNLFKGTDITQKFAKGEVIESFEVNSLKHSIAQYRSRLSDISWFMRCLNEPIARMANKEDKCTGRFWEGRFKSQALLDDAAVLACMAYVDLNPIRAKMATTPENSNFTSIQRRIKAALNGEQPTSLLPFVGNERNEMPKGLMFNAKDYLQLVDDTGRIIRQDKRGAISQTSQRILDRLNIPQENWLKLSTDFGDLFKGAVGTLQELDAFCEHQEKKRRQGAANCHRWLDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC4</accession>
    <name>B1KMC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322886.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0236"/>
    <dbReference type="EnsemblBacteria" id="ACA84537">
        <property type="protein sequence ID" value="ACA84537"/>
        <property type="gene ID" value="Swoo_0236"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0236"/>
    <dbReference type="eggNOG" id="ENOG50348BN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141049_0_0_6"/>
    <dbReference type="OMA" id="ESICSMI"/>
    <dbReference type="OrthoDB" id="2068876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="18224" checksum="CFCE107A226651EA" modified="2008-04-29" version="1">MSVIQAIGQQNIKAEFAHRLQGFLSQDPDVRELFSGATSMTTVVNLLAALSFQEGDARFQTDALDEELVFSLFFDSFYLLFIKELEHNNLSQAEKLILQLSRYYGELMAKRIVQAETGLGAEELSIRAELLKRANCVLQAWEQLDKRYAQQRGNSRNMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMF9</accession>
    <name>B1KMF9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase IS3/IS911 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase 8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85957">
        <property type="protein sequence ID" value="ACA85957"/>
        <property type="gene ID" value="Swoo_1672"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1672"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_33_2_6"/>
    <dbReference type="OMA" id="RDGHERC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038965">
        <property type="entry name" value="InsF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46889:SF1">
        <property type="entry name" value="PTHR46889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="214"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="383" mass="44872" checksum="B9F22033456DB278" modified="2008-04-29" version="1">MREKRYPDEFKIEAVKQVTERGHQIADVAERLGVTPKSFHNWINKFDKPEKQHTTIDNQQAEIRKLKAELRRVTKERNILKEATVYFASESKKKYTFIKSRLRQYPIRTLCKTLGVNRSDFYSWLKEPHSPRAIEDKRLLGKIKQYWLESGCVYGYINITLDLKDDGETVGKNRVYRIMSQAKIKAIRSYKRNPSFGGGNVSHTAPNTLNRGFDVDKPNKVWVTDFTFIRTHEGWLYLTVVIDLFSRQVVGWTMKSSAKADLVIDALLMAVWRRSPSEKVLIHSAQGVQYTSSNWRSFLKENNLQASMSRRGKCHDNAVAESFFSLLKKDRVKRKIYRTRAEARSEIFNYIEYFYNPVRHHGSNNGLSPMKFEKQYYENLESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ0</accession>
    <name>B1KMJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphonate ABC transporter, periplasmic phosphonate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324334.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1703"/>
    <dbReference type="EnsemblBacteria" id="ACA85988">
        <property type="protein sequence ID" value="ACA85988"/>
        <property type="gene ID" value="Swoo_1703"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1703"/>
    <dbReference type="eggNOG" id="COG3221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051472_7_0_6"/>
    <dbReference type="OMA" id="AYMNPYH"/>
    <dbReference type="OrthoDB" id="988224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767207" evidence="1">
        <location>
            <begin position="26"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="34149" checksum="CB88309E50C9DB50" modified="2008-04-29" version="1" precursor="true">MSISTLFKQLFLLTFICSVNLSVNAQTIENKNDSLHSDEPVTLTFGVVPQQAASTLARLWSPVFEVMSQNANFQLRFATARDIPTFEKRLAQGEYDIAYMNPYHYTVFHDSVGYQALVKQKGKQIKGIIVVREDSPIQTLDELESQVLAYPAPAAFAASVLPRANLKLKNIETKVKYVGSHDSVYLAVAQGLVAAGGGVQRTFKTMDKQITEQLRVLWVTPGYTPHAIAFHPRVPKSLIEEVQLKMLELTSSIEGRDALERLGFSRFEQASNGDWDDVRALGLGSFSKPLEQAKERKGTSHNMEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMK5</accession>
    <name>B1KMK5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fumarylacetoacetate (FAA) hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324349.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1718"/>
    <dbReference type="EnsemblBacteria" id="ACA86003">
        <property type="protein sequence ID" value="ACA86003"/>
        <property type="gene ID" value="Swoo_1718"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1718"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050185_0_0_6"/>
    <dbReference type="OMA" id="QLIAHIC"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041072">
        <property type="entry name" value="FAA_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18288">
        <property type="entry name" value="FAA_hydro_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydro_N_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="83"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="328" mass="36069" checksum="3DA16566DCBC1ADC" modified="2008-04-29" version="1">MKLASYNNGRRDGQLMLVSKDLTKAVAVPAIAHTMQELLDAWQLLQPQLSELYDALNDGLIDNAIEFDEAKCLSPLPRAYQWADGSAYVNHVELVRKARGAQMPETFWTDPLVYQGGSDCFIAPKADIPLANEEWGIDFESEIAVITDDVPMGVSTENAEKHIKLLMLVNDVSLRNLIPGELAKGFGFYQAKPSSSFSPVAVTPDELGKRWEDSKVHLPLITHLNRELFGQPNAGVDMTFNFSQLVSHVAKTRPLGAGAIIGSGTISNYDRSAGSSCLAETRMLETIADGKPATSFMKFGDRVRIEMLDDNNETIFGSIDQQVVEYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KML6</accession>
    <name>B1KML6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FeoA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3123</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FeoA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325730.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3123"/>
    <dbReference type="EnsemblBacteria" id="ACA87394">
        <property type="protein sequence ID" value="ACA87394"/>
        <property type="gene ID" value="Swoo_3123"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3123"/>
    <dbReference type="eggNOG" id="COG1918">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150646_12_4_6"/>
    <dbReference type="OMA" id="NPGEHAT"/>
    <dbReference type="OrthoDB" id="2047422at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="3">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="9833" checksum="C70189635A9C9FCE" modified="2008-04-29" version="1">MKLSDLNPGEHATIAVVGQLDLPAVVKRKLLSMGITPNTRFRLLRKAPLGSGLELDIRGSRLCMRRDLADIIEVERVEVVELEVEKANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP6</accession>
    <name>B1KMP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325760.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3153"/>
    <dbReference type="EnsemblBacteria" id="ACA87424">
        <property type="protein sequence ID" value="ACA87424"/>
        <property type="gene ID" value="Swoo_3153"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3153"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_8_5_6"/>
    <dbReference type="OMA" id="DHTTINR"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="94"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="283" mass="31897" checksum="78E0025356479336" modified="2008-04-29" version="1">MSPTLPKIECHINVDSCEANAASLLANKSGLSKQQIKQAMTKGAVWHTRKHNTSRLRRGKKSLKVGDELHLYYNQEVLEHQIDDAELIADMGQYSLWYKPYGMLCQGSKWGDHTTINRYSETHLTPDRPAFIVHRLDRAATGLVLIGHSKSITAALAKLFELRELDKYYQVIVEGRFNSGREEVVTVDSDVDNKSACSHAKLLEYDAKQNRSLVQVKIDSGRKHQIRIHMASLGHPVVGDRLHGIASGSDINLQLTSCYLKFPCPVTGEINEFELPERLRPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMR4</accession>
    <name>B1KMR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325778.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87442">
        <property type="protein sequence ID" value="ACA87442"/>
        <property type="gene ID" value="Swoo_3171"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3171"/>
    <dbReference type="eggNOG" id="ENOG5030T3P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_184538_0_0_6"/>
    <dbReference type="OMA" id="QYEIVIN"/>
    <dbReference type="OrthoDB" id="2063237at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="103" mass="11706" checksum="CF72EF7AC090F4EE" modified="2008-04-29" version="1">MIDQANNLPIPSYQTFKQLIGKTVNVEDPQGNHLELIIDEIVTGSAHNQNYESFTTRLKDTLPNRVPQGCYTFSHPIIGKQWLFCSAISATQYEIVINREVEL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMY7</accession>
    <name>RS7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsG</name>
        <name type="ordered locus">Swoo_4694</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327263.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMY7"/>
    <dbReference type="SMR" id="B1KMY7"/>
    <dbReference type="STRING" id="392500.Swoo_4694"/>
    <dbReference type="EnsemblBacteria" id="ACA88944">
        <property type="protein sequence ID" value="ACA88944"/>
        <property type="gene ID" value="Swoo_4694"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4694"/>
    <dbReference type="eggNOG" id="COG0049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072226_1_1_6"/>
    <dbReference type="OMA" id="NVMPHVE"/>
    <dbReference type="OrthoDB" id="1540940at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000126002" description="30S ribosomal protein S7">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <sequence length="156" mass="17751" checksum="4D0B8A15EC39A1E3" modified="2008-04-29" version="1">MPRRRVVGQRKILPDPKFNSELLAKFINVIMQDGKKSTAEKIIYKALDTVAEKKSEDHLVILEAALENVRPSVEVKSRRVGGSTYQVPCEVRPVRRNALGMRWLVEAARKRGEKSMALRLAGELLDASENKGTAVKKREDVHRMAEANKAFAHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE3</accession>
    <name>B1KNE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP dicarboxylate transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1735</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324366.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1735"/>
    <dbReference type="EnsemblBacteria" id="ACA86020">
        <property type="protein sequence ID" value="ACA86020"/>
        <property type="gene ID" value="Swoo_1735"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1735"/>
    <dbReference type="eggNOG" id="COG1593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019824_4_0_6"/>
    <dbReference type="OMA" id="MSLWLSW"/>
    <dbReference type="OrthoDB" id="903568at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="6"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="428" mass="45771" checksum="5E5C4B5200E89D27" modified="2008-04-29" version="1" precursor="true">MLAFTLIVLLVLLALSIPIASSLGILAFSLDSKYSSLPLYKAVGEIAWSSSTDFLLLAIPLFILLGEIMLRSGTAERMYDGLVKWISWLPGGLLHSNIGACALFAATSGSSVATAATVGTVALPQIKKQKYNESLFLGTLAAGGTLGILIPPSINMIIYGVLTDTSVPKLYMAGIIPGIVLAGLFTLLIIVLCSCKKSLGGESLHYSWSGKLSSLPSLLPPLFIFIIVVGAIYGGFATPTEAAALGVVGSLGIAFKQGKLSFSMLKLALEGTVKTSSMVLLIIICAYFLNFVLAGIGLTDEINRIIVELEWSPTQTILAIIIFYLVLGCFMETLSMMITTVPIMAPIVIGMGYDPIWFGILLMVLLETALISPPIGLNLYVVQGVRERGDISDVMLGVIPFFMAMLAMIVLIVFIPEMVMWLPELIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF5</accession>
    <name>B1KNF5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated CheW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1747</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1747"/>
    <dbReference type="EnsemblBacteria" id="ACA86032">
        <property type="protein sequence ID" value="ACA86032"/>
        <property type="gene ID" value="Swoo_1747"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1747"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048995_0_0_6"/>
    <dbReference type="OMA" id="AFMVRSI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024181">
        <property type="entry name" value="Chemotax_regulator_CheV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002867">
        <property type="entry name" value="CheV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="3">
        <location>
            <begin position="9"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="172"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="32794" checksum="C510260679DA46EC" modified="2008-04-29" version="1">MMKSKASQSQGLLLFRLSHKQLFAVGTLKVRELVPYTPLNAIPHSHPTILGAATIRGNTIPVIDMAAAVGYQGLSQDEYAKSYIVITDCQRMVIGFLVRGIDKIIECNWRDIESPPNNLGPNAYLTGVTRFEEGLVQLLDVELLLSKVFPESPETSRAILTDVQREKLKPLRILLVDDSKVARKQLSDALDRINIPYQVTSDGHDALSIMQNAAEKREPIDMLVSDIEMPGLDGYELAFEVKNTPALAQAYIILHTSLSSEISIGQAQQVGANEALEKFDAHELISAMLRGAESKAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNT3</accession>
    <name>B1KNT3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lpxD</name>
        <name evidence="8" type="ordered locus">Swoo_3271</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325877.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3271"/>
    <dbReference type="EnsemblBacteria" id="ACA87541">
        <property type="protein sequence ID" value="ACA87541"/>
        <property type="gene ID" value="Swoo_3271"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3271"/>
    <dbReference type="eggNOG" id="COG1044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049865_0_1_6"/>
    <dbReference type="OMA" id="QIQIAHN"/>
    <dbReference type="OrthoDB" id="1602061at2"/>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="7">
        <location>
            <begin position="23"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="341" mass="35858" checksum="6F3E15C0F0641F2B" modified="2008-04-29" version="1">MNSYTLRELAEALDAEIQGDETLVISSVATLENAAQGQLSFLANPKYRAQLETTQASAVLISPKALDGFSGNALVLNDPYVGFARVAQLLDTTPKSAVGIHASAVIDPSASLGEGVAIGANAVIGENVILGENVQVGPGCVIGQESILGSGTRLWANVTIYHNVHLGQDCIIHSGAVLGSDGFGYANERGQWIKIPQTGGVRIGNRVEIGASTTVDRGAIEHTEIHDGVILDNQVQIAHNDIIGENVAIAGNSTIAGSTKIGKYCIIGGNSAVAGHLTLADGTHVSGGTNVTSEIREPGVYTSTSVAMPNKLWRRNTVRFKQLDELFQRVKRLEKSVQTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNW3</accession>
    <name>B1KNW3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3302</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325907.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3302"/>
    <dbReference type="EnsemblBacteria" id="ACA87571">
        <property type="protein sequence ID" value="ACA87571"/>
        <property type="gene ID" value="Swoo_3302"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3302"/>
    <dbReference type="eggNOG" id="COG2015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014655_1_0_6"/>
    <dbReference type="OMA" id="KWETLTI"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765090" evidence="5">
        <location>
            <begin position="26"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="131"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="673" mass="74015" checksum="E5A765C87494E24E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP82</accession>
    <name>Y351_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0102 protein Swoo_0351</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_0351</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0102 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323001.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP82"/>
    <dbReference type="SMR" id="B1KP82"/>
    <dbReference type="STRING" id="392500.Swoo_0351"/>
    <dbReference type="EnsemblBacteria" id="ACA84652">
        <property type="protein sequence ID" value="ACA84652"/>
        <property type="gene ID" value="Swoo_0351"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0351"/>
    <dbReference type="eggNOG" id="COG0792">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115353_1_0_6"/>
    <dbReference type="OMA" id="PPCRFDA"/>
    <dbReference type="OrthoDB" id="2044249at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00252">
        <property type="entry name" value="TIGR00252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000091265" description="UPF0102 protein Swoo_0351">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <sequence length="117" mass="13467" checksum="9B8A0D55E4FE5AD4" modified="2008-04-29" version="1">MIDNKHQIPREHGQAGEKLAMNYLAERGLNFVEANVRYKFGEIDLIMKDGKEWIFIEVKYRSKAQYGGALNALSPAQIGRLRRAAEHYIQIHKIDAVCRFDLIAIDASQIHWLPNAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPB0</accession>
    <name>B1KPB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323029.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0381"/>
    <dbReference type="EnsemblBacteria" id="ACA84680">
        <property type="protein sequence ID" value="ACA84680"/>
        <property type="gene ID" value="Swoo_0381"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0381"/>
    <dbReference type="eggNOG" id="COG3788">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134926_1_0_6"/>
    <dbReference type="OMA" id="LPWEQIF"/>
    <dbReference type="OrthoDB" id="1899954at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="14495" checksum="62530AB0367BE0F8" modified="2008-04-29" version="1">MPVAISGLYISITAILVVMFAMRVVKLRRKHKIGIGSSDNKELRIAGRVHANLIENAPIAMALLLVAELNGLTPLALHLLGIMWVIGRVLHAIGLTKGQGGYHIGRFWGGLLSWLMILILAGINLGYFVYSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPB9</accession>
    <name>B1KPB9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4240 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323038.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84689">
        <property type="protein sequence ID" value="ACA84689"/>
        <property type="gene ID" value="Swoo_0390"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0390"/>
    <dbReference type="eggNOG" id="ENOG50337VW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123807_0_0_6"/>
    <dbReference type="OMA" id="FLYSRCV"/>
    <dbReference type="OrthoDB" id="2023464at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025334">
        <property type="entry name" value="DUF4240"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14024">
        <property type="entry name" value="DUF4240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="17078" checksum="C167BF9B2846054C" modified="2008-04-29" version="1">MNEIEFWKLISKLNWDETGDDEAVIEPVVNALAKMDNEDIFHFEEILAQKLFALDTMAHAKEIGDDAYVSDEKYFSPDSFLYSRCVVVANGKAFFEEILANPSEFPKDMEFEAILEISSSAYEEKNDDEWDYVSPTDYESFKNVAGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPJ3</accession>
    <name>B1KPJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324492.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1862"/>
    <dbReference type="EnsemblBacteria" id="ACA86146">
        <property type="protein sequence ID" value="ACA86146"/>
        <property type="gene ID" value="Swoo_1862"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1862"/>
    <dbReference type="eggNOG" id="ENOG5032KTM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1632138_0_0_6"/>
    <dbReference type="OMA" id="NENWESW"/>
    <dbReference type="OrthoDB" id="1913074at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="18118" checksum="F219BA67413A44BB" modified="2008-04-29" version="1">MNVELIGNFVGLTLAHTGFIGSGQNGELMVPYLILQSGAKREVQNFEAATQQEAIELAHKAIEEQQDSVDAWSYAQEGVVELEDGTKQDVYLIKAWSNELAQPVQLYQRCQSSPFKLIGNIQILNFEEAGFSMEDADTFMNALNNGILSHKSANENWESWFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPK3</accession>
    <name>B1KPK3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1872</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324502.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1872"/>
    <dbReference type="EnsemblBacteria" id="ACA86156">
        <property type="protein sequence ID" value="ACA86156"/>
        <property type="gene ID" value="Swoo_1872"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1872"/>
    <dbReference type="eggNOG" id="COG0007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_7_0_6"/>
    <dbReference type="OMA" id="FIHRLML"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="286" mass="30192" checksum="20E668BD3F826495" modified="2008-04-29" version="1">MKTADVIKLDLNRYSSTPPKVAIVGAGCGEVELLTLKAARYISKADVIIYDSLVCEEILTLASSRCAMHFVGKRCGQPSAKQDEINALLVASARGGGFVVRLKGGDPNIFGRGCEEALYLAESGIKSEFVPGVTAALGCAASAGIPLTHRGVARSVTFVTGRVFDNSAQSWSALLCAETSLVFYMGKEQAGNIAKGLLAAGASIELPMAFITNGARVDQDVVYAKLGSMAMVAQRLVVEGPTLIIVGEVVNVAQTLSELVLSIEERGSQRVSEHSDNQMNPSRLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPK5</accession>
    <name>B1KPK5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Response regulator with putative antiterminator output domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324504.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1874"/>
    <dbReference type="EnsemblBacteria" id="ACA86158">
        <property type="protein sequence ID" value="ACA86158"/>
        <property type="gene ID" value="Swoo_1874"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1874"/>
    <dbReference type="eggNOG" id="COG3707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119074_0_0_6"/>
    <dbReference type="OMA" id="FECANKI"/>
    <dbReference type="OrthoDB" id="2004274at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005561">
        <property type="entry name" value="ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50921">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ANTAR" evidence="1">
        <location>
            <begin position="121"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="20346" checksum="F2912D81724F1AA1" modified="2008-04-29" version="1">MRLLIVSEGNKLDFANVSSYLKSEVELLISSSLSELERISLDIENDVLLLSVTTFTQRELAFLQRLIAFSAIPLLINAQSWQADDLKSLLTCGRVTFVPGQLEMSRLNDLLVLAKLRYELAEQQLQEISTLQGCLQEQKQMARVKSKLQATGLSESQAHQLLQKEAMKQGIPLAQLVKQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPK6</accession>
    <name>B1KPK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Nitrite reductase (NAD(P)H), large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Swoo_1875</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nitrogen metabolism; nitrate reduction (assimilation).</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1875"/>
    <dbReference type="EnsemblBacteria" id="ACA86159">
        <property type="protein sequence ID" value="ACA86159"/>
        <property type="gene ID" value="Swoo_1875"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1875"/>
    <dbReference type="eggNOG" id="COG1251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_0_0_6"/>
    <dbReference type="OMA" id="IVIGHGM"/>
    <dbReference type="UniPathway" id="UPA00653"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012744">
        <property type="entry name" value="Nitri_red_NirB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017121">
        <property type="entry name" value="Nitrite_Rdtase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037149">
        <property type="entry name" value="NirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02374">
        <property type="entry name" value="nitri_red_nirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="24"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_C" evidence="16">
        <location>
            <begin position="343"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="14">
        <location>
            <begin position="438"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="13">
        <location>
            <begin position="581"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="12">
        <location>
            <begin position="653"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR037149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA86159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="880" mass="96022" checksum="0CC1869DD5FA5913" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM5</accession>
    <name>B1KPM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324524.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1894"/>
    <dbReference type="EnsemblBacteria" id="ACA86178">
        <property type="protein sequence ID" value="ACA86178"/>
        <property type="gene ID" value="Swoo_1894"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1894"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_1_6"/>
    <dbReference type="OMA" id="MCGLIKR"/>
    <dbReference type="OrthoDB" id="1497607at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="168" mass="18718" checksum="9C03A12A30A37F73" modified="2008-04-29" version="1">MIVLETDRLRLRYLTLGDAAFILELLNTPGFLDNIGDRGVRDRYQAETYLIEGPIASYQEHGFGLYLVELKSTGERIGLSGIVKRENLQFPDLGYAFLPHFWGKGYALESGKGVLSHAKKLALSNILGVVSPGNDASIAVLEKLGMQFECHQKWSDGSDILRYNLQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPV9</accession>
    <name>B1KPV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family with aminotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325977.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3373"/>
    <dbReference type="EnsemblBacteria" id="ACA87642">
        <property type="protein sequence ID" value="ACA87642"/>
        <property type="gene ID" value="Swoo_3373"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3373"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_1_6"/>
    <dbReference type="OMA" id="HERRQVM"/>
    <dbReference type="OrthoDB" id="1320028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="484" mass="55017" checksum="F8AFA3ED01B16751" modified="2008-04-29" version="1">MKALTLTLTQPAKPKFLQIARAIISAIKQGKVNAKEPLPSARQLAAELKTNRHTIMAAYQELIAQGWVQSIERQGYRVVESIPVESSRHARKSLKCEKNTFIWQINPTAFELDNSKPAHEYSYNFAGGNPDISAFPFHELKPYMSESLTRPRLNHLSYGNNRGDDQFISQLATYLRRARSITNKEIITVNGSQEALYLLSQVLLKPGSKVAVESLGYRPAWNAFTTAGAELVAIKQHSKGIDIEHLTQLVKQQSISLIYLTPLHQYPTTVTLPIHERGKIYQLAAKYQIAIVEDDYDHEFHYSSQPLAPLAANDPQGLVIYLSTFSKIMFPGCRIGYMAVDKSLAPALINYRSVMNHKPNVLMQDAIGRWMKEGSFERHLRRTTKQYQQRRNNLISQLEQYQEQGLDISFTIPAGGMAIWLDVKKNAKELERFALAHDIYLVSESGFHLDKENDENRYIRLGFAGMKPEKMNQGLAILFSYFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ04</accession>
    <name>B1KQ04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327434.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4868"/>
    <dbReference type="EnsemblBacteria" id="ACA89117">
        <property type="protein sequence ID" value="ACA89117"/>
        <property type="gene ID" value="Swoo_4868"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4868"/>
    <dbReference type="eggNOG" id="ENOG5033HTK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190005_0_0_6"/>
    <dbReference type="OMA" id="ASEMFKY"/>
    <dbReference type="OrthoDB" id="2102772at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="78" mass="9156" checksum="002A5CF0EFAE7D4E" modified="2008-04-29" version="1" precursor="true">MDKEIIIMVIMLALIISTAISEGLKHYFRMKKITKADIKLDELELLRKQNRHLEDRVQTLEKIVTDSSYDLKQQINAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ14</accession>
    <name>B1KQ14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4878</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4878"/>
    <dbReference type="EnsemblBacteria" id="ACA89127">
        <property type="protein sequence ID" value="ACA89127"/>
        <property type="gene ID" value="Swoo_4878"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4878"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029425_4_0_6"/>
    <dbReference type="OMA" id="SDPAQWC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767552" evidence="2">
        <location>
            <begin position="26"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="279"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="158"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA89127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="378" mass="42229" checksum="AB5677297C8ADD0C" modified="2008-04-29" version="1" precursor="true">MVNFRFLSKASIFAGFIMLSTPLQASDLQQRQSDLKQLQSQISKQQSDLKNTSKQREKLVNLLKKDEKAIASAAKKVNETKTSLTQTDKQLSKLNNRQAELNKLKKIQQESLSNQLASAYLAGNHDYSKMLLNQQSPATIERLLTYYQYLNNARMASINELQATMIELEEITQEQISQKDRLNKLILNQQQQAKQLTLEQSQRQNTLSLLQKTLNSSGAKLEQLQIEEASLKRVVEQAITAMRNSPKMDGLSSKNKLSWPTKGRIKSGFGSQRSGQVKWKGVTVSAPEGQTITAIAPGKVIYADWLRGFGMVLVVDHGKGYMSLYGHAQTLLKNAGDLVNKGESVALVGRSGGQTEPGLYFEVRHKGQAVDPARYCKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ27</accession>
    <name>B1KQ27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327457.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4891"/>
    <dbReference type="EnsemblBacteria" id="ACA89140">
        <property type="protein sequence ID" value="ACA89140"/>
        <property type="gene ID" value="Swoo_4891"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4891"/>
    <dbReference type="eggNOG" id="COG2706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_651931_0_0_6"/>
    <dbReference type="OMA" id="PTIVKQY"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="434" mass="46270" checksum="D6A9B879104DEA8B" modified="2008-04-29" version="1">MKKTDTLKLHQFLLPIVTVGLISLLGCESKVVQTSREALSTIYVASNKADGNTVVGFRSLANGKFKQLGEFPTGGEGTGDLEIPALQKDETHPLANGDDPLISANGIVATDDGRHVLVVNAGDSTISLLRVNKDGSLTQKNTVEAGDKFPVSIASHGQHVVVASVGVDNGNGSISAYIINTDNRLTLVPGSRRDLKARPSTTSFSHDGKHLIVNELVTGKIKIFRMLDNSLSAEPISTINSPRTAKRFQAIPVGFDTGVSDSGDLIFMSEARFLTPEFGLREQANVVPQTPKYSWQTGSLSSYTLDGQGNISLVSADVLTGNSVEGGEIANCWVALSPDQKTLWAANALSSSISSFDISNDGSVRLKNATAYKSKPEMLFFSDLDTSHDGKELYQLVGNMGQVMIFDIQNNGDLTVKQTLSGLPKLGAYGLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ29</accession>
    <name>B1KQ29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4893</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327459.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4893"/>
    <dbReference type="EnsemblBacteria" id="ACA89142">
        <property type="protein sequence ID" value="ACA89142"/>
        <property type="gene ID" value="Swoo_4893"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4893"/>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060699_0_1_6"/>
    <dbReference type="OMA" id="MTKRNTQ"/>
    <dbReference type="OrthoDB" id="1629121at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="28284" checksum="57A42401989EDDA1" modified="2008-04-29" version="1">MNKRNTQQRRHSIISILNEQGEVSVDELSTRFETSEVTIRKDLAALEKTGLLLRRYGGAVAIPDEVTQQFTAKIAPNKLSIAETAAELINDHNRIIIDSGSTTSGLIQQLNSKRGLLVMTNSLQLANAIHELENEPTLLMTGGTWDPHSESFQGQVAEQVLRSYNFDQLFIGADGIDLERGTTTFNELTGLSKVMAEVSREVIVMLESDKVGRRIPNLELPWSKVSVLVTDDRLAAEAVESITNHGVRVILARHVS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ65</accession>
    <name>YIDC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yidC</name>
        <name type="ordered locus">Swoo_4929</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327494.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ65"/>
    <dbReference type="SMR" id="B1KQ65"/>
    <dbReference type="STRING" id="392500.Swoo_4929"/>
    <dbReference type="EnsemblBacteria" id="ACA89178">
        <property type="protein sequence ID" value="ACA89178"/>
        <property type="gene ID" value="Swoo_4929"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4929"/>
    <dbReference type="eggNOG" id="COG0706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016535_3_0_6"/>
    <dbReference type="OMA" id="INPVAGC"/>
    <dbReference type="OrthoDB" id="524437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019998">
        <property type="entry name" value="Membr_insert_YidC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028053">
        <property type="entry name" value="Membr_insert_YidC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038210">
        <property type="entry name" value="YidC_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038221">
        <property type="entry name" value="YidC_periplasmic_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14849">
        <property type="entry name" value="YidC_periplas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00701">
        <property type="entry name" value="60KDINNERMP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01900">
        <property type="entry name" value="YIDCPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03593">
        <property type="entry name" value="yidC_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000187707" description="Membrane protein insertase YidC">
        <location>
            <begin position="1"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01810"/>
        </source>
    </evidence>
    <sequence length="544" mass="60964" checksum="6377B0082A8186DF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE6</accession>
    <name>FIS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-binding protein Fis</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fis</name>
        <name type="ordered locus">Swoo_0504</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulatory Fis family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005496187.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQE6"/>
    <dbReference type="SMR" id="B1KQE6"/>
    <dbReference type="STRING" id="392500.Swoo_0504"/>
    <dbReference type="EnsemblBacteria" id="ACA84801">
        <property type="protein sequence ID" value="ACA84801"/>
        <property type="gene ID" value="Swoo_0504"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0504"/>
    <dbReference type="eggNOG" id="COG2901">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158040_3_3_6"/>
    <dbReference type="OMA" id="MVLCEVE"/>
    <dbReference type="OrthoDB" id="1933378at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00166">
        <property type="entry name" value="DNA_binding_Fis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005412">
        <property type="entry name" value="Fis_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002097">
        <property type="entry name" value="DNA-binding_Fis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01591">
        <property type="entry name" value="DNABINDNGFIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000097465" description="DNA-binding protein Fis">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00166"/>
        </source>
    </evidence>
    <sequence length="101" mass="11411" checksum="4D86E35DEDB92F8A" modified="2008-04-29" version="1">MFDQTTNTETHQLTVGKIETANGTIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSEVEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR1</accession>
    <name>B1KQR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3399</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326002.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3399"/>
    <dbReference type="EnsemblBacteria" id="ACA87667">
        <property type="protein sequence ID" value="ACA87667"/>
        <property type="gene ID" value="Swoo_3399"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3399"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_32_6"/>
    <dbReference type="OMA" id="RGRHWGG"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="84"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="526" mass="57261" checksum="8FD5800152E87A69" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU5</accession>
    <name>B1KQU5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326036.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3433"/>
    <dbReference type="EnsemblBacteria" id="ACA87701">
        <property type="protein sequence ID" value="ACA87701"/>
        <property type="gene ID" value="Swoo_3433"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3433"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_6"/>
    <dbReference type="OMA" id="CMVTLSA"/>
    <dbReference type="OrthoDB" id="1204683at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="22031" checksum="05508B033D209351" modified="2008-04-29" version="1">MARSCGFDREEKLVLAMELFWQQGYEATSIADLVSHLGINRFSLYNTYGDKLTLYRESLKYYLEQYSQPKLTPMVENSGLDGVLAYIESFVAIQKDQKYGCFLQNAILEKIISDDVVKEQCERLFDGILTGFNYNLAYAKSVGEITSEVDSMQVSRFLLMQMQGIRVLGKAGQYEVIDDAFRVLKSYLISLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU9</accession>
    <name>B1KQU9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative periplasmic ligand-binding sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326040.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3437"/>
    <dbReference type="EnsemblBacteria" id="ACA87705">
        <property type="protein sequence ID" value="ACA87705"/>
        <property type="gene ID" value="Swoo_3437"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3437"/>
    <dbReference type="eggNOG" id="COG3416">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082335_5_0_6"/>
    <dbReference type="OMA" id="FASEYCE"/>
    <dbReference type="OrthoDB" id="1764423at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018648">
        <property type="entry name" value="DUF2076"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09849">
        <property type="entry name" value="DUF2076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="218" mass="23128" checksum="B34B73478944981E" modified="2008-04-29" version="1">MTPQEQELIQNVANKLKASPSKAKDLDAENLISQEIASQEDIVYKLTQAVLVQEMALKELKSKSDFLESQVEHFRKESERGTLSRMMGGTNPAPVQPQPVRQPSAFGSFMQTAAGVAAGMVAGNLISNALFGEDEPTAEATPEVAPETESSPTETAAAETAAPEDTSSSFLDSNSDFASEYSEPSTDFGSDTFANSGFGGDESFGGFDDGGFGDDEDF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR07</accession>
    <name>UBIE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE</fullName>
            <ecNumber evidence="1">2.1.1.163</ecNumber>
            <ecNumber evidence="1">2.1.1.201</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-methoxy-6-polyprenyl-1,4-benzoquinol methylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Demethylmenaquinone methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiE</name>
        <name type="ordered locus">Swoo_0527</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.163"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:28286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="EC" id="2.1.1.201"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="1"/>
    <dbReference type="EC" id="2.1.1.201" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323172.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KR07"/>
    <dbReference type="SMR" id="B1KR07"/>
    <dbReference type="STRING" id="392500.Swoo_0527"/>
    <dbReference type="EnsemblBacteria" id="ACA84824">
        <property type="protein sequence ID" value="ACA84824"/>
        <property type="gene ID" value="Swoo_0527"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0527"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_0_0_6"/>
    <dbReference type="OMA" id="VRNFENL"/>
    <dbReference type="OrthoDB" id="1431378at2"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00169"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043333">
        <property type="term" value="F:2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="chain" id="PRO_1000187813" description="Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="123"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01813"/>
        </source>
    </evidence>
    <sequence length="251" mass="27894" checksum="007C319EF24ED604" modified="2008-04-29" version="1">MSEGTPNSTHFGYKTVESDQKADMVAGVFHSVAAKYDIMNDVMSFGIHRMWKRFTIESAGARPGMKVLDLAGGTGDLTAKFSHIVGDKGQVTLADINDSMLKVGREKLRDKGIVGNVNYVQANAEALPFPDNHFDIITIAFGLRNVTDKDAAIRSMLRVLKPGGKLLVLEFSKPKHDVMRKVYDLYSFKVMPKMGALITQDAESYEYLAESIRMHPDQETLKGMMVDAGFEQVEYTNMTDGIVALHKGYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR45</accession>
    <name>B1KR45_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminotransferase class V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0566</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323210.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0566"/>
    <dbReference type="EnsemblBacteria" id="ACA84862">
        <property type="protein sequence ID" value="ACA84862"/>
        <property type="gene ID" value="Swoo_0566"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0566"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_0_6"/>
    <dbReference type="OMA" id="LMICTMA"/>
    <dbReference type="OrthoDB" id="839689at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="675"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="771" mass="84316" checksum="68ECC4BBAB7D6ED6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR79</accession>
    <name>B1KR79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323244.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0600"/>
    <dbReference type="EnsemblBacteria" id="ACA84896">
        <property type="protein sequence ID" value="ACA84896"/>
        <property type="gene ID" value="Swoo_0600"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0600"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="INCVGGY"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="34315" checksum="A745B5D037C5D179" modified="2008-04-29" version="1">MNKDLNLADIRAFTVIAEQGSFTQAAEVLGCSRSHLSKQLLQLENLLGVSLITRTTRAQRLTEQGRFFFDSCQAALESIDQAVAVTVDNAQRLQGHININCVGGIIGEEIVTALVNDFISQYPDISVHLDFSSPRVDLVVDEFDLVFRMGELEDSAIVARKLMSIENMTMASPQYLAAHGYPNHPKDLKEHLCITGSIDHWLFEKRDDAKSKVEVAIKGGFKCKNGRVMKSAALADNGIVRLPRLYCPNELAKGELVSVFEDWRVADTPFYLLYCKDRFQPARLRAFISFTMKNFMKYVTDVKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRQ4</accession>
    <name>B1KRQ4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipoprotein NlpI</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May be involved in cell division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326152.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3555"/>
    <dbReference type="EnsemblBacteria" id="ACA87819">
        <property type="protein sequence ID" value="ACA87819"/>
        <property type="gene ID" value="Swoo_3555"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3555"/>
    <dbReference type="eggNOG" id="COG4785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071600_0_0_6"/>
    <dbReference type="OMA" id="VEHRYSF"/>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023605">
        <property type="entry name" value="Lipoprotein_NlpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004654">
        <property type="entry name" value="NlpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR004654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="302" mass="34065" checksum="BAD27DFEFE487DC4" modified="2008-04-29" version="1" precursor="true">MIQKVRTAAVVVLAGMSILLTGCISTQSGGSEQGKVMVEPVMPDYKLEITLAKLNEILSSAELTDAQRARFHYDRGVIYDSVGLRILSRIDFHQALKMQPNLADAYNFIGIYYTQEGEFESAYEAFDAVLELSPDYDYAFLNRGIALYYGERNELAASDMESFYSLDPQDGYRALWLYVTESANNLEQAKSNLAENSLRLNPNTWSSVLVDFYLGKKSRDEVFAAAKEGLSHPNEYAERLCEAYFYIAKIAQQKGQNIDAANYFRLALATNIYDFVEHRYARIELAKINAVISAEKMSDSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRR6</accession>
    <name>B1KRR6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326164.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="SMR" id="B1KRR6"/>
    <dbReference type="STRING" id="392500.Swoo_3567"/>
    <dbReference type="EnsemblBacteria" id="ACA87831">
        <property type="protein sequence ID" value="ACA87831"/>
        <property type="gene ID" value="Swoo_3567"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3567"/>
    <dbReference type="eggNOG" id="COG0294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008023_1_3_6"/>
    <dbReference type="OMA" id="FSIDTYH"/>
    <dbReference type="OrthoDB" id="1275854at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="2">
        <location>
            <begin position="16"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="30520" checksum="3B78F1B00088AC89" modified="2008-04-29" version="1">MYKIRSGEKSLDLASPVVMGILNVTPDSFSDGGQFASFQRACEHADQMVAQGASFIDIGGESTRPGAAEVSLDEELLRVIPLIEYVAKHHDVWVSVDTSKAEVMEAAVNAGANLINDVRALQEEGALEVAAKLQVPVCLMHMQGQPRTMQTSPEYRDVVEDIKRFFESRIQACIDAGIKRENIILDPGFGFGKTLSHNYELLNRLAEFQELGLPLLIGVSRKSMMGNLLNRDTSERLAGSLAGVLLAAQRGGDIFRVHDVPETVDVLKVLLATSHYKNI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX3</accession>
    <name>DNAA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dnaA</name>
        <name type="ordered locus">Swoo_0001</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322651.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCX3"/>
    <dbReference type="SMR" id="B1KCX3"/>
    <dbReference type="STRING" id="392500.Swoo_0001"/>
    <dbReference type="EnsemblBacteria" id="ACA84302">
        <property type="protein sequence ID" value="ACA84302"/>
        <property type="gene ID" value="Swoo_0001"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0001"/>
    <dbReference type="eggNOG" id="COG0593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026910_0_1_6"/>
    <dbReference type="OMA" id="REFNPLF"/>
    <dbReference type="OrthoDB" id="219876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000122017" description="Chromosomal replication initiator protein DnaA">
        <location>
            <begin position="1"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="167"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <sequence length="462" mass="52210" checksum="575A69B7FFE1E64D" modified="2008-04-29" version="1">MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIINQFFTEQMGSDAPKLRFDIGSRPSAPKPIQATAAVVKPKLESSPQKSQTSFNVNAPEPAATANHRSNINPTYQFENFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDTKEDYANLIRTLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD23</accession>
    <name>B1KD23_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326191.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3594"/>
    <dbReference type="EnsemblBacteria" id="ACA87858">
        <property type="protein sequence ID" value="ACA87858"/>
        <property type="gene ID" value="Swoo_3594"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3594"/>
    <dbReference type="HOGENOM" id="CLU_1892618_0_0_6"/>
    <dbReference type="OMA" id="WLINIKV"/>
    <dbReference type="OrthoDB" id="2102302at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764295" evidence="1">
        <location>
            <begin position="25"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="15090" checksum="0C3C9BFC1EAA9143" modified="2008-04-29" version="1" precursor="true">MKKFNIFSPLVFTLLLLFSAGSQCGYENVDISEEKKMIEVLYGVEVYSDSFEFQVLSSGCTHNEHFKLQASQLNDNQISVQLIRTKKDLCRALPWLINIKVAIPFSDILYPEFIFTNPFKNKHSLKNTYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF8</accession>
    <name>B1KDF8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sel1 domain protein repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323306.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0663"/>
    <dbReference type="EnsemblBacteria" id="ACA84959">
        <property type="protein sequence ID" value="ACA84959"/>
        <property type="gene ID" value="Swoo_0663"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0663"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1073228_0_0_6"/>
    <dbReference type="OMA" id="GVERNCG"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764711" evidence="1">
        <location>
            <begin position="25"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="259" mass="28309" checksum="6CCEA3F19A9AE97B" modified="2008-04-29" version="1" precursor="true">MKFHPLIIGAGFVITSVMSTAAHAFSIPQPATAEAASKLAHIELKATQGEQEAQFLLGLMYLSGRFVAQDQPLGIKWVTLAAEQGHVKAQQTIADLSFEGNIIARDLAVAERWYLSLSEQGSKWAEFRLGFIYAAGGEGVQRNCGKAVKHFSAVGDEVSLGNVAWILSTCPEAKYRNGDRALELAQSLVKANQEDPTNLDNLAAAYAEIGDFSSAIVTQQKAIHALKLSEQVDRSDEFELRLQTYEQNKPFREKVPLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDI2</accession>
    <name>B1KDI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, NifA subfamily, Fis Family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0688</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323330.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0688"/>
    <dbReference type="EnsemblBacteria" id="ACA84983">
        <property type="protein sequence ID" value="ACA84983"/>
        <property type="gene ID" value="Swoo_0688"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0688"/>
    <dbReference type="eggNOG" id="COG3604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_125_2_6"/>
    <dbReference type="OMA" id="HLEVHDC"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="194"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="528" mass="57920" checksum="3AC2312908CF8D3B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ9</accession>
    <name>B1KDJ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323347.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0705"/>
    <dbReference type="EnsemblBacteria" id="ACA85000">
        <property type="protein sequence ID" value="ACA85000"/>
        <property type="gene ID" value="Swoo_0705"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0705"/>
    <dbReference type="eggNOG" id="ENOG5033DVG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169692_0_0_6"/>
    <dbReference type="OMA" id="WGETELK"/>
    <dbReference type="OrthoDB" id="1960724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022069">
        <property type="entry name" value="DUF3622"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12286">
        <property type="entry name" value="DUF3622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="13223" checksum="E7F55F523ABFBD9E" modified="2008-04-29" version="1">MTQTKKFDFRIVQDKDVWAAEITRRMTARKTIVSKRKTGFATEAEATAWGEKELKSFLDNLMERNERKAKQREVRNDAAAAKELAADAWRDARDVADGDRTFDEDSDDYASDEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM3</accession>
    <name>B1KDM3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324765.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2136"/>
    <dbReference type="EnsemblBacteria" id="ACA86420">
        <property type="protein sequence ID" value="ACA86420"/>
        <property type="gene ID" value="Swoo_2136"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2136"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016532_0_0_6"/>
    <dbReference type="OMA" id="QYDWEPV"/>
    <dbReference type="OrthoDB" id="227881at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010727">
        <property type="entry name" value="DUF1302"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06980">
        <property type="entry name" value="DUF1302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767272" evidence="1">
        <location>
            <begin position="32"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="682" mass="74528" checksum="A5AE7A7D6C372DB6" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV5</accession>
    <name>B1KDV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PhoH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3697</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326289.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3697"/>
    <dbReference type="EnsemblBacteria" id="ACA87957">
        <property type="protein sequence ID" value="ACA87957"/>
        <property type="gene ID" value="Swoo_3697"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3697"/>
    <dbReference type="eggNOG" id="COG1702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051654_0_1_6"/>
    <dbReference type="OMA" id="NLCGQFD"/>
    <dbReference type="OrthoDB" id="445854at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="4">
        <location>
            <begin position="117"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="39267" checksum="E998794F32B96259" modified="2008-04-29" version="1">MSNKLTTLNLYLEPADTRRLLSLCGPFDDNIKQLERRIGVEISYRDNHFQIVGQAKNCLSVNNLLKSLYVETQSVKGSTPDLEPDTVHLAIQEAVALEAELPRDDKELYIKTKRGVIKPRNPNQSDYVANIATHDITFGIGPAGTGKTYLAVAAAVDALERQEVRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMMGFEKVERLIERNVIEVAPLAYMRGRTLNDAFIILDESQNTTVEQMKMFLTRIGFNSRAVITGDITQIDLPKHQKSGLRHAIEVLSEVEEISFNFFQAKDVVRHPVVARIVEAYEEHDQKAQIAKAKRENHYKLQEATENEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDZ7</accession>
    <name>B1KDZ7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Azurin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers electrons from cytochrome c551 to cytochrome oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326331.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3740"/>
    <dbReference type="EnsemblBacteria" id="ACA87999">
        <property type="protein sequence ID" value="ACA87999"/>
        <property type="gene ID" value="Swoo_3740"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3740"/>
    <dbReference type="eggNOG" id="COG3241">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112845_1_0_6"/>
    <dbReference type="OMA" id="MGHNFVL"/>
    <dbReference type="OrthoDB" id="1735306at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13922">
        <property type="entry name" value="Azurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014068">
        <property type="entry name" value="Azurin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02695">
        <property type="entry name" value="azurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006522151" description="Azurin" evidence="1">
        <location>
            <begin position="34"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="2">
        <location>
            <begin position="35"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="16873" checksum="980CCF94E74A1727" modified="2008-04-29" version="1" precursor="true">MKISINRLKTISAVGLLGFSALCSLSFSAAANASECELAISANDAMQFNTKELSVPASCKEVTLTLTHAGQLPATAMGHNWVLTKVADMSAVANEGMGAGAALSYVKDGDKRVIAHTDIVGGGASTSITFSTEGMSPSESYKFFCSFPGHWAIMQGDFIIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE73</accession>
    <name>B1KE73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0764"/>
    <dbReference type="EnsemblBacteria" id="ACA85059">
        <property type="protein sequence ID" value="ACA85059"/>
        <property type="gene ID" value="Swoo_0764"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0764"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_665123_0_0_6"/>
    <dbReference type="OMA" id="FWKEYNN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="297"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="345"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="407" mass="46288" checksum="BC22F97A283083B6" modified="2008-04-29" version="1">MLNGFEQMRFIITFLIFFSGHSLSNEDPLADNKVTCEEMETSPELVFKLNDLGSGRGSPNEVDYYCPKSLNQLGFLQKVIAQAGSIRSPSWLPQYCTGTIIYAQRRYYHFSLAKLGYFPQGSSFKKNGKTHGIEYSKEWSYQSLYNREIYTAYIKEVEAAKPKLEEWYIKNHHVTRDVAKKYTDIALQSISNYGFGSYFYNWTPEPLIPFTEEAIKGNFTNFLSSISSSSEPQKLNSLRRLLTHQAPTKIIEKLASTIATKTPSKRSESIISSSIKEPLNVKALLDSDFPIDHQNEFGKTALFYAIQFNQHDSVKLLLSYGANVNHTYQQEEKEDKWSCSGIEQWGRTPLMHAAQHSDIDMLNLLINNQADIKAKDIKGSTAFDYAENSDKKENASFLLKEVGALSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE84</accession>
    <name>B1KE84_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MltA-interacting MipA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MipA/OmpV family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323417.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0775"/>
    <dbReference type="EnsemblBacteria" id="ACA85070">
        <property type="protein sequence ID" value="ACA85070"/>
        <property type="gene ID" value="Swoo_0775"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0775"/>
    <dbReference type="eggNOG" id="COG3713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_643952_0_0_6"/>
    <dbReference type="OMA" id="RVAHGWA"/>
    <dbReference type="OrthoDB" id="611922at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010583">
        <property type="entry name" value="MipA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06629">
        <property type="entry name" value="MipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="52081" checksum="4759BD5794BBE7A3" modified="2008-04-29" version="1" precursor="true">MNNPIGIIAGLAALTFTQLSTASQVQDGVHSEPQHEVIYETQYQADIWGLGMGMRRGDIPFATEDDEVYDILPMLKYRNDYLFIDGMEAGLHLWKNEQHQVNAYTRFRFVDIPKELQNESQSQAFDFGLQYRFQQGPWEADAAFLSDSNKRSYGYTRTQYHWEKGGLYLNPYAEFHWKSADFNEYYYGLDQYEVGAGVEFNAGIKARYHLVSNLYLLGQFGVGRLEDEVAHLPSMDTQYQYESYFGFAFYPDAKSRESMAVRSSSPETDDDSEFLRLAHGWATPSNLNEIMTGSARTDPYNNQLTSLFYGTRLTDTLFTLPIELYFTPGAVWHHDSEVQGDLAEAVIAIKAFYTFEFGPKWRLGVAEGLSYISSVSHIEGTELEEKGYKPSKLLNYLDFSLDVNLGDIFNRHDMRNLWLGYSIHHRSGIYEKSSAFGRIGGGSNYQSVYLQWHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE90</accession>
    <name>B1KE90_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_0781</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323423.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0781"/>
    <dbReference type="EnsemblBacteria" id="ACA85076">
        <property type="protein sequence ID" value="ACA85076"/>
        <property type="gene ID" value="Swoo_0781"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0781"/>
    <dbReference type="eggNOG" id="COG1718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047558_0_0_6"/>
    <dbReference type="OMA" id="EIRCAKV"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO" evidence="12">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="284" mass="31777" checksum="1F924768DE995B53" modified="2008-04-29" version="1">MKIPKRIQPLVDEGLVDEVLRPLMSGKEADVFVVRSGGDVRCAKIYKEAEKRSFKQAVQYREGRKSRNSRRSRAMEKGSKFGRSEQESAWQNAEVDALYRLAHAGVRVPQPYGCFDGVLLMELITDDEGFVAPRLNDVSLSSEQALEQHKAVMKDVQRMLCAGLIHGDLSEFNVLLDSSGPVIIDLPQAVDAAANNNAKRMLERDVNNMTQYYGQFAPELLGSKYAKEMWALFESGKLTPDVELTGKFKESTKAADVDSVLAEIEAAFDEEQERKERIREAAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA9</accession>
    <name>B1KEA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_2205</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324831.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2205"/>
    <dbReference type="EnsemblBacteria" id="ACA86487">
        <property type="protein sequence ID" value="ACA86487"/>
        <property type="gene ID" value="Swoo_2205"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2205"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_28_3_6"/>
    <dbReference type="OMA" id="DFKNLCM"/>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="217"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="393"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="449" mass="49553" checksum="6C29E21B3F0482A5" modified="2008-04-29" version="1">MPFSKLGLSEPILNAVTELGYTTPTPIQAEAIPLALKGKNLIAAAQTGSGKTASFVLPILELLSAGETQRKKRARALVLTPTRELAVQVCKSIELYGKHLNLNAIAIYGGVDYAPQKQALIDGVDIVVATPGRLRDLYTQRAIHFDETTLLVLDEADRMLDMGFIEDITKIIDTLPEQRQSLLFSATLSRQVRELAKETVCDAIQLSFNKENEAKPNIEQWITTVDKDKKSALLSHLINEQNWPQALIFIETKHGAAKLVSQLEKRGIEAECIHSGRTQAIREQILADFKSGKIRYLISTGISARGIDIDELPLVINYDLPFPADEYVHRIGRTGRAGSAGEAISLVSKDDFKNLCMIESRLNHLLERRVIEGFSPRKEVPVSVLNYVPKSQRDEDGKRIKSEKSAKSGAVRSKAKSSKPSNRLGDGKSTESSKSNTQAGFNPWTDGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB2</accession>
    <name>B1KEB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2208"/>
    <dbReference type="EnsemblBacteria" id="ACA86490">
        <property type="protein sequence ID" value="ACA86490"/>
        <property type="gene ID" value="Swoo_2208"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2208"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022247_1_0_6"/>
    <dbReference type="OMA" id="FWTNGSY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033856">
        <property type="entry name" value="Trp_halogen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011396">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="502" mass="56573" checksum="F5A7955EE65E0722" modified="2008-04-29" version="1">MHSPIKKIVIVGGGTAGWMAAAMLVRFLGKQLTITQIESDKVGTVGVGEASIPPLKMFNQALDIDEHEFLKATNGTYKLGIEFDNWAQEGDSYMHAFGPLGKDLALTPFHHYYLNHYLKSEHQISKQLGKYSLNYLSAKKNNFQPLDAIAGTGLPGLTYAYHFDASLYAKYLKSYSKQAGVDSIEGLVIRTNLNSSNGAIDSVTLASGQTIEGDLFIDCSGFKGLLIEQALNSGYEDWRHWLPCDSALAVASEVKKPISPYTRSTANEAGWQWRIPLQSRTGNGIVYSSQFINDEQAEKLLFKQLDGKPLTLPQKVNFVTGRRKHQWLKNCISLGLASGFVEPLESTSLHLVQSGIIRLLKLFPSQEMEQANIDQYNQQSKQEFEQIRDFIILHYRLSGQKQTPFWQYCREMPIPNSLQQKLDLFKASGVVSRYQDELFTENAWVQVMLGQRFTPNTYSTLTENINTTQNIQFLNDLHKIFDTTSSKLMSHDSYLTQYCGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEC7</accession>
    <name>B1KEC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324849.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86505">
        <property type="protein sequence ID" value="ACA86505"/>
        <property type="gene ID" value="Swoo_2224"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2224"/>
    <dbReference type="eggNOG" id="ENOG50309KR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138350_1_0_6"/>
    <dbReference type="OMA" id="WWVNIPL"/>
    <dbReference type="OrthoDB" id="1771843at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12682" checksum="F987E83E9E66FD66" modified="2008-04-29" version="1" precursor="true">MKKVKIFQLLLSFLSVCGWSLAVYALIVFDKARPDRAVGYYLSKGSSVRLGWDQTHTIELEYVIWTCAAISFISLAFNYYFAHHSKMGYWFNIPLLLTASLAAGLYVRFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN1</accession>
    <name>B1KEN1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3787</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3787"/>
    <dbReference type="EnsemblBacteria" id="ACA88046">
        <property type="protein sequence ID" value="ACA88046"/>
        <property type="gene ID" value="Swoo_3787"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3787"/>
    <dbReference type="eggNOG" id="COG4772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_17_0_6"/>
    <dbReference type="OMA" id="IREDGPN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="6">
        <location>
            <begin position="70"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="5">
        <location>
            <begin position="288"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="751" mass="82951" checksum="B143ED6BC4A0B37A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES2</accession>
    <name>B1KES2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Disulphide bond formation protein DsbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3828</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326417.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3828"/>
    <dbReference type="EnsemblBacteria" id="ACA88087">
        <property type="protein sequence ID" value="ACA88087"/>
        <property type="gene ID" value="Swoo_3828"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3828"/>
    <dbReference type="eggNOG" id="COG1495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045364_0_0_6"/>
    <dbReference type="OMA" id="GLHTQFW"/>
    <dbReference type="OrthoDB" id="284148at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003752">
        <property type="entry name" value="DiS_bond_form_DsbB/BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023380">
        <property type="entry name" value="DsbB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02600">
        <property type="entry name" value="DsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158442">
        <property type="entry name" value="SSF158442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="482" mass="52832" checksum="5ED339BC5B8B8311" modified="2008-04-29" version="1" precursor="true">MKMKESTVNQIVSLAAMALIALPVGIACIILGYGLGDTPCILCWQERTAMVLVALIAIFITRYGLKPKYLGALILASVYGLWAGYRHSSNHILKDIGQGFGPAIFGVHTYVWVMVVFLVILLFAAVLLMLQGDKLSEKEDKNSWTLLNRSTVMVFLVVIGFNIVQAFSQTGPFPFIGQSDPYRMTFDSDKIVWSTANWPKLSSLSARGSYAIERPDFANMAEVEGSEVSNQPSLNALRTQKLPTEITGVATGISYSANSDIYAVVTSDNWVHFLNGKLDKVLASVMIDGAFSVEISNLTGVAFDGDNSVLVTADHKSYVRLEYDPLAKISDSYYLFMDGTDGVKELKRSRFSTVRAKYNYIGSLGWDAATQEYVTVTLPAKVRNNFVISRFSNQDFELNSEAKIINPAETFPMVTGLAIEQDKAYLLNHSAKQVLEMTMATNSIDAAYSFDGVSNPQGLALVNGEFAVLNGAQGQNSVSFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF34</accession>
    <name>B1KF34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0891</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0891"/>
    <dbReference type="EnsemblBacteria" id="ACA85185">
        <property type="protein sequence ID" value="ACA85185"/>
        <property type="gene ID" value="Swoo_0891"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0891"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_18_2_6"/>
    <dbReference type="OMA" id="VAKNDWK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="377"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="44621" checksum="8BB6D6F350C705F1" modified="2008-04-29" version="1" precursor="true">MIKIIRRLTPLFILFFFGMAAWLLINTKESPEQKEEEKPAQIVDVVKVEQQTVSLNLPSYGVVTPKNKTQLVTEVKGRLLSISPNFVAGGVVKKGEQLAMIEPSDYEADLSQAQASLAQAQAALEEEIARGEVAKNDWKGYDGGLPPELGLRLPQLKKEQANVKFAQAAMARAERNLERTIIRAPFEGIIKTRMVDLGQYVTLGTNLGELYDTRIAEIRLPLANNDLAYLESVDKPDTQVTLSASLVGKEVSWTGDIVRSEGVIDADNRMVYLVAEIKDPYLRESKHQGQLPLKYGSFVTAIIKGRTVEGIVKLPRHIVRNNQVAVVSSDNIVEVRDVNIVRTDVDSVYIKDSLLDGERISLTKLSSMRSGQSVKILGEADNSGSKSPQTDEDKEQHLAAKGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF81</accession>
    <name>B1KF81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324964.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2343"/>
    <dbReference type="EnsemblBacteria" id="ACA86622">
        <property type="protein sequence ID" value="ACA86622"/>
        <property type="gene ID" value="Swoo_2343"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2343"/>
    <dbReference type="eggNOG" id="COG1748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063454_0_0_6"/>
    <dbReference type="OMA" id="HTSGPFQ"/>
    <dbReference type="OrthoDB" id="1006830at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="4"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="41189" checksum="E311DD862C8F7F2A" modified="2008-04-29" version="1">MRKVVVLGGYGNFGKRIVENLADIDGITVMIAGRSSDKALSLIEKLKPGAAADLKPLVIDIFSQHFKDQLAKISPYLVIHTSGPFQAQDHRVPKACLDCGAHYIDLADDRRFVCDISELNAQAKERELLVVSGASSVPGLSSAVVDHYEKQFNLINSIELSIAPGNKAERGLATIEGILSYTGHAIKVFKDGRWQGAYGWMDSKVNDFGLFVGKRHLANVDVPDLELFPHRYRVSKQVSFQAGLEIPLLHLTMVGMAYLAKIGLVTNWAPLSKIIMSTSNLFISLGSDEGAMQVSINGVDNNQGAKQIKWTLYAPQGNGPHIPTLSTIILARKLLCEEKLDPAQFTGAKPCLGLLKLTEFNSYFDALNIFFEDKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFG3</accession>
    <name>B1KFG3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326468.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3880"/>
    <dbReference type="EnsemblBacteria" id="ACA88138">
        <property type="protein sequence ID" value="ACA88138"/>
        <property type="gene ID" value="Swoo_3880"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3880"/>
    <dbReference type="eggNOG" id="COG2119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040186_2_1_6"/>
    <dbReference type="OMA" id="PDKMDDD"/>
    <dbReference type="OrthoDB" id="2050363at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="20224" checksum="246BB4C5DB7A7B26" modified="2008-04-29" version="1">MEALLASTLTVAIAEIGDKTQLLALILAARFSHLSGAKTAIILGIFLSTLANHFAAAWVGQWAISFISPELGRYLVAGSFFAIALWVLVPDKVDEEQSRFYKMGPFLATFILFFIAEMGDKTQVATVVLSAKYDALAMVVMGTTLGMMIANVPVVIAGHFSAERLPMTLIHRGCAVLFALLGVVTLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL5</accession>
    <name>B1KFL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326520.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3932"/>
    <dbReference type="EnsemblBacteria" id="ACA88190">
        <property type="protein sequence ID" value="ACA88190"/>
        <property type="gene ID" value="Swoo_3932"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3932"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="KHRYITH"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="33602" checksum="3A5B307C7DF83087" modified="2008-04-29" version="1">MDKYESMQLFIHTSRSGSFTAAADELNLTQSAVSKKIAWLEKKLGFTLFHRNSRKIQLTTQGKNYLSYCKQALDEMTYIESQLKGELNAVIGELRLSVPSAMATQILAKPISDFMAIHPQLTVNISVNDRQVDLIESKVDIAIRVATLPDSGYKARFLFNNQSIMFASPSYLKDKGTPKTAEELTTHQCLVYSLKAPSNIWSLTDSNNTTVKVKVKERVKSDSAEMLLKMSLMGHGISALPNWMVKQHIDNGRLTAILVDYQSMSLPMYAVFKADGYQPYRIQAFVNFLAEYFQDNID</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT2</accession>
    <name>RPIA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="1">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphoriboisomerase A</fullName>
            <shortName evidence="1">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpiA</name>
        <name type="ordered locus">Swoo_0955</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323595.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KFT2"/>
    <dbReference type="SMR" id="B1KFT2"/>
    <dbReference type="STRING" id="392500.Swoo_0955"/>
    <dbReference type="EnsemblBacteria" id="ACA85248">
        <property type="protein sequence ID" value="ACA85248"/>
        <property type="gene ID" value="Swoo_0955"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0955"/>
    <dbReference type="eggNOG" id="COG0120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056590_1_1_6"/>
    <dbReference type="OMA" id="YDWDEVN"/>
    <dbReference type="OrthoDB" id="1681738at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="PTHR11934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000097693" description="Ribose-5-phosphate isomerase A">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="28"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="81"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <sequence length="218" mass="23324" checksum="074B0388354A10D0" modified="2008-04-29" version="1">MTQDEMKKAAGWAALEYVEKDSIVGVGTGSTVNHFIDALATMKAEIEGAVSSSEASTQKMKDLGIPVFDLNSVDELSVYVDGADEINAHMDMIKGGGAALTREKIVAAVADKFICIVDNTKQVDVLGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGVITDNGNIILDVYNMKIVNPKELEQQINKIVGVVTNGLFANRGADVLLVGSPDGVKTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT8</accession>
    <name>B1KFT8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323601.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85254">
        <property type="protein sequence ID" value="ACA85254"/>
        <property type="gene ID" value="Swoo_0961"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0961"/>
    <dbReference type="eggNOG" id="ENOG5033M28">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2755640_0_0_6"/>
    <dbReference type="OMA" id="NKHKGRV"/>
    <dbReference type="OrthoDB" id="2056418at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="70" mass="7675" checksum="9641DAB516B728FA" modified="2008-04-29" version="1">MGPFEIAAIAIIGAFSVSAYKEYNKRKGDVDSGEVDALKAELVKLQERVATLETIVTDKSYQLGEQINKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFU6</accession>
    <name>B1KFU6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0231 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323609.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0969"/>
    <dbReference type="EnsemblBacteria" id="ACA85262">
        <property type="protein sequence ID" value="ACA85262"/>
        <property type="gene ID" value="Swoo_0969"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0969"/>
    <dbReference type="eggNOG" id="COG3112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139226_1_0_6"/>
    <dbReference type="OMA" id="FSMDHEA"/>
    <dbReference type="OrthoDB" id="1944901at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008249">
        <property type="entry name" value="UPF0231"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06062">
        <property type="entry name" value="UPF0231"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006287">
        <property type="entry name" value="UCP006287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="14257" checksum="73FB6BB99A5B00CC" modified="2008-04-29" version="1">MEYEFRRNTLTGTVMANFSMDHEALGFWFAEELGECAEKYNEICQVAAKLQSNQLIHWRMVGKALSLELDAEQARIFANELENGEEFELEDAMSLYDGESEAYCGLEDFQAALESWHAFLTETH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFU9</accession>
    <name>NRFA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytochrome c-552</fullName>
            <ecNumber evidence="1">1.7.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ammonia-forming cytochrome c nitrite reductase</fullName>
            <shortName evidence="1">Cytochrome c nitrite reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nrfA</name>
        <name type="ordered locus">Swoo_0972</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>6 Fe(III)-[cytochrome c] + 2 H2O + NH4(+) = 6 Fe(II)-[cytochrome c] + 8 H(+) + nitrite</text>
            <dbReference type="Rhea" id="RHEA:13089"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.7.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="1">Binds 1 Ca(2+) ion per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="1">Binds 5 heme c groups covalently per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; nitrate reduction (assimilation).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome c-552 family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323612.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KFU9"/>
    <dbReference type="SMR" id="B1KFU9"/>
    <dbReference type="STRING" id="392500.Swoo_0972"/>
    <dbReference type="PRIDE" id="B1KFU9"/>
    <dbReference type="EnsemblBacteria" id="ACA85265">
        <property type="protein sequence ID" value="ACA85265"/>
        <property type="gene ID" value="Swoo_0972"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0972"/>
    <dbReference type="eggNOG" id="COG3303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035040_1_0_6"/>
    <dbReference type="OMA" id="EMVILWA"/>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="UniPathway" id="UPA00653"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042279">
        <property type="term" value="F:nitrite reductase (cytochrome, ammonia-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00548">
        <property type="entry name" value="NrfA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01182">
        <property type="entry name" value="Cytochrom_C552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003321">
        <property type="entry name" value="Cyt_c552"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017570">
        <property type="entry name" value="Cyt_c_NO2Rdtase_formate-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30633">
        <property type="entry name" value="PTHR30633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02335">
        <property type="entry name" value="Cytochrom_C552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000243">
        <property type="entry name" value="Cyt_c552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03152">
        <property type="entry name" value="cyto_c552_HCOOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51008">
        <property type="entry name" value="MULTIHEME_CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0106">Calcium</keyword>
    <keyword id="KW-0249">Electron transport</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0574">Periplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5000316547" description="Cytochrome c-552">
        <location>
            <begin position="28"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01182"/>
        </source>
    </evidence>
    <sequence length="466" mass="52301" checksum="6271DBE4E8959CAB" modified="2008-04-29" version="1" precursor="true">MVRILTKKSFALSALVAASLMASGAMASDKTEPRNEQYKDKFSKQYNSWHETSESVEITDALEQDPNLVILWAGYGFAKDYNKARGHMYAVTDLRNTLRTGAPKKDTDGPMPMACWSCKSPDVPRMIEEQGEDGYFSGKWYKGGAEIVNTIGCSDCHEKGKSKLRISRPFAERGMEAIGTPFDKASRKDKQSMVCGQCHVEYYFEKTADKKGFVKFPWDKGTTVEDMEAYYDAIDFADWTHKVSKTPMLKAQHPGYETWQLGMHGKNNVSCTDCHMPKVKNAEGRKFTDHKVGNPFDRFEETCGNCHDQSKEFMVNLDKERKAKVKEIQLRAENQLVKAHFEAGAAWKAGATEAEMKPILTDIRHAQWRWDYAIASHGVASHAPDEALRVLGTAVDKAADARVKLAQLLAKKGVPQPIALPDISTKAKAQAALGMDMKKMNADKEEFKKTVLPKWDAEAKKREATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV3</accession>
    <name>B1KFV3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5-carboxymethyl-2-hydroxymuconate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323616.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0976"/>
    <dbReference type="EnsemblBacteria" id="ACA85269">
        <property type="protein sequence ID" value="ACA85269"/>
        <property type="gene ID" value="Swoo_0976"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0976"/>
    <dbReference type="eggNOG" id="COG3232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139188_2_1_6"/>
    <dbReference type="OMA" id="HVFANIM"/>
    <dbReference type="OrthoDB" id="1965508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008704">
        <property type="term" value="F:5-carboxymethyl-2-hydroxymuconate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00580">
        <property type="entry name" value="CHMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004220">
        <property type="entry name" value="5-COMe_2-OHmuconate_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37950">
        <property type="entry name" value="PTHR37950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02962">
        <property type="entry name" value="CHMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12260" checksum="82F8E649F3AF0225" modified="2008-04-29" version="1">MPHCVIEHSGNIEGDLLIASVYQGALASNLFEAEGSDIKVRALPYANYQTGNVELKFVHVTLKILSGRNLEQKSRLTELVLAQLKKLQMTDCSISVEVADIERDSYAKVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG30</accession>
    <name>B1KG30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325079.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2460"/>
    <dbReference type="EnsemblBacteria" id="ACA86737">
        <property type="protein sequence ID" value="ACA86737"/>
        <property type="gene ID" value="Swoo_2460"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2460"/>
    <dbReference type="eggNOG" id="ENOG502Z8J0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061973_0_0_6"/>
    <dbReference type="OMA" id="WQYIEAF"/>
    <dbReference type="OrthoDB" id="1068071at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021452">
        <property type="entry name" value="DUF3103"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11301">
        <property type="entry name" value="DUF3103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764426" evidence="1">
        <location>
            <begin position="26"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="411" mass="45575" checksum="0440F99C7C90DD6C" modified="2008-04-29" version="1" precursor="true">MKNLSLSLLMLTVPLFTATSYSVNAQPLGLSGSSELQQINQGYSVAEAKREIAIELSRQYTQIAPVLQSNINQYSLTMDADQVFTQSKIDAQTLHQAEVKIRTAKGLSINTKSNTPSSGYRTSDIDNNLVQFRLADVSMLEAWQQGESPLFAFEPDGDDKQWVNIEAYDIDGNIHLLDVYQLPQRPVVVIALDKQSVISEGLAVMRKTFAAGTGPSKAESLTLRHRQSKSLSTSSEDQAISTTVLKRISLQDDQEPWISGKAEIYAIVTGVNPSRDEPVLDIIEMPYLDYSDTQYYPNQIMIHWERYRWAAADLVLMEHDDGTNYKELASALLLAAEQILKAIPDPEVQGFAIIATITNGILAAMPDAWFTNDDDYVDVYYTLQEGETYTNHSGAGGNANAHFAPLTIQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGF5</accession>
    <name>B1KGF5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326621.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4036"/>
    <dbReference type="EnsemblBacteria" id="ACA88292">
        <property type="protein sequence ID" value="ACA88292"/>
        <property type="gene ID" value="Swoo_4036"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4036"/>
    <dbReference type="eggNOG" id="COG3576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054794_1_1_6"/>
    <dbReference type="OMA" id="RITLMWC"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="11"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="21324" checksum="7F93AA9F4E30727D" modified="2008-04-29" version="1">MGKQFAELSSKHIEFIEKQKIYFVATAAQTGCVNLSPKGGDSLRVISSSKIAWLNLTGSGNESASHVLQDPRMTIMFCAFEGSPLILRTYGQAEVLHVNDAEWEQYAKLFPESVAARQIFVLDITLVQSSCGMSVPYFTFESDRDDLAKWSDKHGTEGIEKYWVKRNQKSIDGFDTEIVQRAGIKQNSSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGI2</accession>
    <name>B1KGI2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LPS-assembly protein LptD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lptD</name>
        <name evidence="5" type="ordered locus">Swoo_1017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LptD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323657.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1017"/>
    <dbReference type="EnsemblBacteria" id="ACA85310">
        <property type="protein sequence ID" value="ACA85310"/>
        <property type="gene ID" value="Swoo_1017"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1017"/>
    <dbReference type="eggNOG" id="COG1452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009039_2_0_6"/>
    <dbReference type="OMA" id="DYSHLDW"/>
    <dbReference type="OrthoDB" id="100018at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015920">
        <property type="term" value="P:lipopolysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010033">
        <property type="term" value="P:response to organic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01411">
        <property type="entry name" value="LPS_assembly_LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020889">
        <property type="entry name" value="LipoPS_assembly_LptD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007543">
        <property type="entry name" value="LptD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04453">
        <property type="entry name" value="LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03968">
        <property type="entry name" value="LptD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009007462" description="LPS-assembly protein LptD" evidence="2">
        <location>
            <begin position="19"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="OstA-like_N" evidence="3">
        <location>
            <begin position="55"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="LptD" evidence="4">
        <location>
            <begin position="296"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="773" mass="88852" checksum="E8FCCC81BA8BF469" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK7</accession>
    <name>B1KGK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323681.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1042"/>
    <dbReference type="EnsemblBacteria" id="ACA85335">
        <property type="protein sequence ID" value="ACA85335"/>
        <property type="gene ID" value="Swoo_1042"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1042"/>
    <dbReference type="eggNOG" id="ENOG503327F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136234_0_0_6"/>
    <dbReference type="OMA" id="TWWLWRQ"/>
    <dbReference type="OrthoDB" id="1769588at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="157" mass="17851" checksum="6EC71D2CB5EA2462" modified="2008-04-29" version="1">MNAPFRYTTSYILDKNYFTECFEASVTEDRTLQSYYKTIGFFLVGTALLLTGVNAYASLFIVGLGAIEGLSVRFKKSWWLWRQMMSKAANNEVKLTIDELGIDTQSDFVKGHIPWKEVIEHKVGDNGYLIKHSGGTSYLSKKLLDTNVIEFINSKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT2</accession>
    <name>B1KGT2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325142.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2524"/>
    <dbReference type="EnsemblBacteria" id="ACA86801">
        <property type="protein sequence ID" value="ACA86801"/>
        <property type="gene ID" value="Swoo_2524"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2524"/>
    <dbReference type="eggNOG" id="COG3456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051329_1_0_6"/>
    <dbReference type="OMA" id="DAIHNLY"/>
    <dbReference type="OrthoDB" id="550490at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017735">
        <property type="entry name" value="T6SS_FHA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03354">
        <property type="entry name" value="VI_FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="424" mass="47637" checksum="382B280A1CDF621E" modified="2008-04-29" version="1">MPFVNFTQQGGVLGCDINADWRLKDRSGGVKPQHCRIMWVDDQFCLEDLCGEVFVNNSSLPIGLGRFASLNENDEIKIGPYKVRISLGLSSDPTASMTKRFSEMFSENDLPGLMKEPVSQVAEHSDDTSIDDPMLALDALQNRSGENILSFDSRKEKKLDDIDLIDTDISISDREITMQADSEYTQDSAIALKKHTELDGFTMDENTLDLLESELHAGLDKQGEQLGEHITTGPLFRGLGVQIGSSQNSEQMQDLSVDLGAALKSAITGLLSLHHTANHSRYELMNKNLQPIEDNPLRLGLGYEDTVKTLFAHDRSPVHLSSAAAIAESLKSIEHHNEAVQSAITEALDYILGAFSPAKLLKRFAQYRKSSDLNLDTGDKWAWSMYEQYYEELTSNRQKGFEKLFWEVFEQAYDRKLRELQKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH74</accession>
    <name>B1KH74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323728.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1089"/>
    <dbReference type="EnsemblBacteria" id="ACA85382">
        <property type="protein sequence ID" value="ACA85382"/>
        <property type="gene ID" value="Swoo_1089"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1089"/>
    <dbReference type="HOGENOM" id="CLU_1864324_0_0_6"/>
    <dbReference type="OrthoDB" id="2060080at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="15099" checksum="C24405B978DF4772" modified="2008-04-29" version="1">MLTRLIYLIIFIVGITLGASSTYLYFHDNSEQRPDTHELIEKILKYSNIPISADNYACEGKAVKTVGSVVASLLELNKMNKVNMLTYGCFGNSCTVSVSSCQPWQDSECSSRFLKFNVDSSNEIKPNTFSCFDMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH98</accession>
    <name>B1KH98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methylmalonate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1113</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323752.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1113"/>
    <dbReference type="EnsemblBacteria" id="ACA85406">
        <property type="protein sequence ID" value="ACA85406"/>
        <property type="gene ID" value="Swoo_1113"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1113"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_10_6"/>
    <dbReference type="OMA" id="HIYGNDG"/>
    <dbReference type="OrthoDB" id="490746at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="15"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="496" mass="53245" checksum="0704F48A716F2120" modified="2008-04-29" version="1">MQQINHYINGAHTDKSERSSPVFEPATGEPKAKVSLASAAEVAGAIELAKKAHSSWSQVSPLNRSRVLFKFKALVEQNMDELAELITREHGKVLDDAKGEIIRGLEVVEFACGIPHLLKGEHTEQVGGGVDAWCVNQSLGVVAGIAPFNFPVMVPMWMFPIAIAAGNTFIMKPSEKDPSSVMRMAQLLTEAGLPDGVFNVVNGDKEAVDTLLSHPDIHAVSFVGSTPIAEYIYETASKHGKRVQALGGAKNHMLLMPDADINQAVGALMGAAFGSAGERCMAISVVLAVGDSGDALVEKLLPQIQALRVGNGVTPEMDMGPLISAQHLAKVTSYVDTGVAEGASLLADGRTLSVEDHEQGYFLGGCLFDNVTPDMTIYKEEIFGPVLAIVRVKDYAEALELINAHEFGNGTAIFTQSGEAARHFCHHVQVGMVGVNVPIPVPMAFHSFGGWKRSLFGPLHMHGPDGVRFYTKRKAITARWPKSSEAKAEFVMPTMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP6</accession>
    <name>B1KHP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2655"/>
    <dbReference type="EnsemblBacteria" id="ACA86931">
        <property type="protein sequence ID" value="ACA86931"/>
        <property type="gene ID" value="Swoo_2655"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2655"/>
    <dbReference type="HOGENOM" id="CLU_2571962_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="81" mass="9722" checksum="1C1BB63F8110EC67" modified="2008-04-29" version="1">MEEQYECENCGRFEVSWVLPLTKRNILLMFIHLMSFILSLVLFLTAPISWLIFIFWLTFSFFFRKLYKAGKRCFACGHLNT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR8</accession>
    <name>RSMC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase C</fullName>
            <ecNumber evidence="1">2.1.1.172</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA m2G1207 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (guanine-N(2)-)-methyltransferase RsmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmC</name>
        <name type="ordered locus">Swoo_4140</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42736"/>
            <dbReference type="Rhea" id="RHEA-COMP:10213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10214"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.172"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmC family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.172" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326725.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHR8"/>
    <dbReference type="SMR" id="B1KHR8"/>
    <dbReference type="STRING" id="392500.Swoo_4140"/>
    <dbReference type="EnsemblBacteria" id="ACA88396">
        <property type="protein sequence ID" value="ACA88396"/>
        <property type="gene ID" value="Swoo_4140"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4140"/>
    <dbReference type="eggNOG" id="COG2813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049581_0_1_6"/>
    <dbReference type="OMA" id="RHCQLWQ"/>
    <dbReference type="OrthoDB" id="1027015at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052914">
        <property type="term" value="F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01862">
        <property type="entry name" value="16SrRNA_methyltr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013675">
        <property type="entry name" value="Mtase_sm_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023543">
        <property type="entry name" value="rRNA_ssu_MeTfrase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08468">
        <property type="entry name" value="MTS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000369783" description="Ribosomal RNA small subunit methyltransferase C">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01862"/>
        </source>
    </evidence>
    <sequence length="345" mass="38121" checksum="7E1E5B1A9BF551EC" modified="2008-04-29" version="1">MLTNPSQLILKNSDLFTSQNVLVLNCEGDLLPKQLLESASCVTTLSLDFHHHLVMSQHSSPNLTLHFGHQLPNADQTFDSVIIYYPKAKALAGYLLNLAGQHLKAEGELIVVGENKGGVKSIVKQIPDYFDTPFKRDNARHCLLFTSQLTQKAPSIKLSDWVNSYQLDTPQGELTICNLVGVFSEKRLDEGTKLLLSHLPRLSRRVLDFGCGAGVIAAALLKAQPELEIECVDINAMALKSCELTLEANNFTAKVYASDGLSQTQGHFDDIISNPPFHDGLKSTTDIAKSFVKESAQKLKSGGGWHIVANRHLPYSDTINEFFGQVNVLAENNKYKIYSNKINQK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS7</accession>
    <name>PEPT_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase T</fullName>
            <ecNumber evidence="1">3.4.11.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Aminotripeptidase</fullName>
            <shortName evidence="1">Tripeptidase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tripeptide aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pepT</name>
        <name type="ordered locus">Swoo_4149</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cleaves the N-terminal amino acid of tripeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of the N-terminal residue from a tripeptide.</text>
            <dbReference type="EC" id="3.4.11.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326734.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHS7"/>
    <dbReference type="SMR" id="B1KHS7"/>
    <dbReference type="STRING" id="392500.Swoo_4149"/>
    <dbReference type="MEROPS" id="M20.003"/>
    <dbReference type="EnsemblBacteria" id="ACA88405">
        <property type="protein sequence ID" value="ACA88405"/>
        <property type="gene ID" value="Swoo_4149"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4149"/>
    <dbReference type="eggNOG" id="COG2195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053676_0_0_6"/>
    <dbReference type="OMA" id="GHNFHGK"/>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00550">
        <property type="entry name" value="Aminopeptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037215">
        <property type="entry name" value="Peptidase_M20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0031">Aminopeptidase</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000200896" description="Peptidase T">
        <location>
            <begin position="1"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00550"/>
        </source>
    </evidence>
    <sequence length="410" mass="45216" checksum="5D2BAFEA4EAF53E6" modified="2008-04-29" version="1">MRQALLTRFLRYIKIDTQSKASNTRSPSSDSQLEFAVILKQELEQLGFERVELSHLGYLTASVPKTVDGVPCIGFIAHLDTAPDFCGANITPQIIENYDGEDILLGDSDLLSTEQFPSLLNYVGQTLITTDGTTLLGGDDKAGIAEIITALAHLIEHPEIPHGEIRLCFTPDEEIGRGAGHFDVPGFGAQWAYTIDGGELGELEYENFNAATAVIRAKGNNCHPGTAYGVMVNAQTMAARFHAKMPLQDTPEGSKDYDGFFHLVNMQGQTEEAELTYLIRDFDIDIFEQRKRWLTERVNSYNADLVVGSLEIEITDSYFNMKEQIIPHPHVVDIAKEAITSQGITPLVKPIRGGTDGARLSYMALPCPNIFTGGHNFHGKHEYICVESMEKAAGVILAICSLTCEKYLNR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ0</accession>
    <name>RS6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsF</name>
        <name type="ordered locus">Swoo_4212</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326796.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHZ0"/>
    <dbReference type="SMR" id="B1KHZ0"/>
    <dbReference type="STRING" id="392500.Swoo_4212"/>
    <dbReference type="EnsemblBacteria" id="ACA88468">
        <property type="protein sequence ID" value="ACA88468"/>
        <property type="gene ID" value="Swoo_4212"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4212"/>
    <dbReference type="eggNOG" id="COG0360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113441_6_0_6"/>
    <dbReference type="OMA" id="ITEASPM"/>
    <dbReference type="OrthoDB" id="1776954at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000120805" description="30S ribosomal protein S6">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="139" mass="15784" checksum="30C03475FEA5A139" modified="2008-04-29" version="1">MRHYEIVFLVHPDQSEQVPGMIERYTGILTQAGGQIHRLEDWGRRQLAYPIIELHKAHYVLMNVEATAESVEELETAFRFNDAVLRNMVMRTKAAITEASPMAKAKDERDSRRASEGERRSAPAEATEEVTEAAEKTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI03</accession>
    <name>B1KI03_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323827.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85481">
        <property type="protein sequence ID" value="ACA85481"/>
        <property type="gene ID" value="Swoo_1188"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1188"/>
    <dbReference type="eggNOG" id="ENOG5031I3Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1199117_0_0_6"/>
    <dbReference type="OMA" id="GNTFFGY"/>
    <dbReference type="OrthoDB" id="2124788at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="235" mass="26307" checksum="77D787CAF1A85E1F" modified="2008-04-29" version="1">MNRSILIIKAYLLATLLSSCVPVPRDFYKPIYEEGTVTSSGCGGAGDPATILIQLEEGIEIKVRASSSDSDDEFVNFYVQTDISAPDGVVFQLANDSMLIEDNLTNKSWRLGIEYLSTNNANYLGLEDSIIEVVYPNLSQKIQAEIKKSHQDTGYIQVEPLSEIIGRTNSYDIAFSKKRYFNTGMWFSTMNQKMESKLENFSVYLPSIIVNGNKVDLGEIKFIHVKYIGIDPLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI44</accession>
    <name>B1KI44_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1229</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1229"/>
    <dbReference type="EnsemblBacteria" id="ACA85522">
        <property type="protein sequence ID" value="ACA85522"/>
        <property type="gene ID" value="Swoo_1229"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1229"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_6_0_6"/>
    <dbReference type="OMA" id="SHEAVMH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="264" mass="27646" checksum="7F7F690FF9568049" modified="2008-04-29" version="1" precursor="true">MVLVFISCLALGAFIGFMAGLLGIGGGVIAVPALLILLPSIGFSSDILPHVAIATSLAAIILTSLSSAQAHHRRGNIPWPIFTTMLPGLILGSICSGFIAKMISAEQLQQIFAFFIILMAIQMVFPFRVAAENKPLPSTLFLFLTSVIIAIIAALMGIGGGILLIPFLSWCGLQMRNAIGFSSASGLFISLFGSLGYVVAGWQVSGLPSGTLGYVYLPALLGIVITSVLMAPLGVRAATHWPTPILKRVFALLLIVTGIKLALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI82</accession>
    <name>B1KI82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323906.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85560">
        <property type="protein sequence ID" value="ACA85560"/>
        <property type="gene ID" value="Swoo_1268"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1268"/>
    <dbReference type="eggNOG" id="ENOG5033HTS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150687_0_0_6"/>
    <dbReference type="OMA" id="QNRRTDP"/>
    <dbReference type="OrthoDB" id="2048507at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="14529" checksum="30E3FAC85BB796C5" modified="2008-04-29" version="1">MLSKPLYEILPITYIATGSISLLVLDSPWGLIAAFTIFYLGSKVYNMRSQNRRTDPVKKRKKGRFPQVIYNSLPFVYLLLAIITYKISTTDLSYIISFSLISYSLYILAKRASNRRHQLPLSHSMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI97</accession>
    <name>B1KI97_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325288.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2672"/>
    <dbReference type="EnsemblBacteria" id="ACA86948">
        <property type="protein sequence ID" value="ACA86948"/>
        <property type="gene ID" value="Swoo_2672"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2672"/>
    <dbReference type="eggNOG" id="COG5646">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130827_1_0_6"/>
    <dbReference type="OMA" id="STLRMDW"/>
    <dbReference type="OrthoDB" id="1278667at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="15790" checksum="8A1E8621152DB5CA" modified="2008-04-29" version="1">MEQGVEDKFQQYPENVKVILLLIRQWILDIFEQERLGELEETLKWGQPSYLVKNGSTIRMDWSAKDPDEIHIFFICNTKLVDTFRELYSDTFIFQGNRAIVLPLDKSLPKEKLRHCLLLALNYHRLKTLPLLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB0</accession>
    <name>B1KIB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325301.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2685"/>
    <dbReference type="EnsemblBacteria" id="ACA86961">
        <property type="protein sequence ID" value="ACA86961"/>
        <property type="gene ID" value="Swoo_2685"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2685"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_9_2_6"/>
    <dbReference type="OMA" id="YHCQDTH"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd04629">
        <property type="entry name" value="CBS_pair_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044729">
        <property type="entry name" value="CBS_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="77"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="138" mass="15222" checksum="7A14E44F0178323B" modified="2008-04-29" version="1">MDSIKITEHMDRQPVLLTADMNLATAVDALLDRNKLGAPVVDDTGHLIGFLSQQDCMSVMLKSSYHCDLVATVSDCMRSDVLWVSPEDSILKLAEQMLGPKPKVYPVVEEGKVVGTINRTNVLNAINIYMQQCYLAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIH1</accession>
    <name>B1KIH1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325358.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2746"/>
    <dbReference type="EnsemblBacteria" id="ACA87022">
        <property type="protein sequence ID" value="ACA87022"/>
        <property type="gene ID" value="Swoo_2746"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2746"/>
    <dbReference type="eggNOG" id="COG0647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_1_1_6"/>
    <dbReference type="OMA" id="PPMHRET"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="26967" checksum="C3106495E343CFC5" modified="2008-04-29" version="1">MKNIICDIDGVLLHNNQLIPGSDKFIHRVLEQGNPLVVLTNYPVQTGKDLQNRLGAAGIKIPEECFYTSAMATADFLKHQTGSKAYVIGEGALTHELYKAGFTITDINPDFVIVGETRSYNWEMIHKAAKFVAEGARFIATNPDTHGPSHSPACGALCAPIERISGRLPFYVGKPSSWIIRSALNHIDGHSDNTIIIGDNMKTDILAGFQAGLETVLVTSGVSQLNDVELEPFRPNHIFPCAGDIDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIJ7</accession>
    <name>B1KIJ7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Lipopolysaccharide export system protein LptC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lptC</name>
        <name evidence="8" type="ordered locus">Swoo_4237</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LptC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326820.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4237"/>
    <dbReference type="EnsemblBacteria" id="ACA88493">
        <property type="protein sequence ID" value="ACA88493"/>
        <property type="gene ID" value="Swoo_4237"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4237"/>
    <dbReference type="eggNOG" id="COG3117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105814_0_0_6"/>
    <dbReference type="OMA" id="YWQVQSK"/>
    <dbReference type="OrthoDB" id="1983716at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015221">
        <property type="term" value="F:lipopolysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01915">
        <property type="entry name" value="LPS_assembly_LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026265">
        <property type="entry name" value="LptC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028513">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04409">
        <property type="entry name" value="LptC_YrbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 6 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR028513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="185" mass="20757" checksum="70F4346612010139" modified="2008-04-29" version="1">MNRVTLAIIAFFGTALLLYWQVQSKRGDEGLAVDVSARPDYIADNLKSVEYNELGLVNSRVSAKHMEHYEEDNMTYFTEPIYLVYPEQGEAQWQLQSTKGTMNKNSGKVILENNVIINAINSNEPIQSIKTSYLELDLNTMIMTSDDNIYITGSDFIIEGVGLYADLNAENVKLTSQVNGTYSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIR3</accession>
    <name>B1KIR3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326886.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4305"/>
    <dbReference type="EnsemblBacteria" id="ACA88559">
        <property type="protein sequence ID" value="ACA88559"/>
        <property type="gene ID" value="Swoo_4305"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4305"/>
    <dbReference type="eggNOG" id="ENOG5031I96">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1776164_0_0_6"/>
    <dbReference type="OMA" id="YERISHY"/>
    <dbReference type="OrthoDB" id="2157161at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="17331" checksum="DF37FEEEA509DEF8" modified="2008-04-29" version="1">MEFKVGSQQTIMFVFEFQSLPSLRGGFRKHYERISHYEPSIKQLDNGRFHLRVTKLVKFDENSISQALEELVEDTQCYGGKFINWKVHKVFNNNSLENKEISIKSKLVNMFTLAGDGRTARRYKMPFYSILLGICVILFASIIQNWVR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIR7</accession>
    <name>CH10_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Chaperonin-10</fullName>
            <shortName evidence="1">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">groES</name>
        <name evidence="1" type="synonym">groS</name>
        <name type="ordered locus">Swoo_4309</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326890.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIR7"/>
    <dbReference type="SMR" id="B1KIR7"/>
    <dbReference type="STRING" id="392500.Swoo_4309"/>
    <dbReference type="EnsemblBacteria" id="ACA88563">
        <property type="protein sequence ID" value="ACA88563"/>
        <property type="gene ID" value="Swoo_4309"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4309"/>
    <dbReference type="eggNOG" id="COG0234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132825_1_1_6"/>
    <dbReference type="OMA" id="KVFYRQW"/>
    <dbReference type="OrthoDB" id="1965002at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000129706" description="Co-chaperonin GroES">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <sequence length="96" mass="10237" checksum="264C60DE7114F6D5" modified="2008-04-29" version="1">MNIRPLHDRVIVKRSEVESKSAGGIVLTGSAAEQSTRGEVLAVGNGRILENGSVQPLDVKVGDMVIFNEGYGVKKEKIDGEEVLILSESDLMAVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIS7</accession>
    <name>B1KIS7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1283</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323921.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1283"/>
    <dbReference type="EnsemblBacteria" id="ACA85575">
        <property type="protein sequence ID" value="ACA85575"/>
        <property type="gene ID" value="Swoo_1283"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1283"/>
    <dbReference type="eggNOG" id="COG1115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024867_0_1_6"/>
    <dbReference type="OMA" id="GMATKFV"/>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="485" mass="51635" checksum="9158C755E62E61EA" modified="2008-04-29" version="1">MFEKLMMWIESAINYTNGLLWGSVLIYVLVAAGVLFTLRLGFIQFRLFGHGVKLVIQGREKIDGISSFQVFCTSMAARVGTGNMAGVAVAITVGGAGAIFWMWLIAMLGMATAFIESTLAQVYKVKDSEGQYRGGPAYYMERGLGKRWMGTIFSILLIIAFGFAFNSVQANTMTDALNNAFGFDKTFIGLVIVLASAYIICGGLKKVAKASELIVPVMAVAYLAIALLVLVTNIEQVPAALSLIVKSALGWEEAAGGAMGAMMAGIARGLFSNEAGMGSAANIAASATPNPNHPASQGFVQMIGVFVDTIVICSSSAAIIMLSGVLDAPNGQEGIGLLQLALNNELGAWSSYFLAFAIILFCFSSIIANYSYAESNVMFLTKSKKVLFIFRGLVLAMVMVGSVASLSLVWNFADVSMGLMALVNIAAIVMLSKVAYSVIKDYELQLKSGVTPTFDSTKFPEIDNLEGGIWVNKNQKTAKSSAETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ87</accession>
    <name>B1KJ87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325443.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87107">
        <property type="protein sequence ID" value="ACA87107"/>
        <property type="gene ID" value="Swoo_2832"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2832"/>
    <dbReference type="eggNOG" id="ENOG5032SIP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1414312_0_0_6"/>
    <dbReference type="OMA" id="ACNHQHQ"/>
    <dbReference type="OrthoDB" id="1840661at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="194" mass="21958" checksum="4E81FBEDC23C4DAB" modified="2008-04-29" version="1" precursor="true">MPLPLLWLGGAAIGAVLLADEREKRHQLELKRRKGIAPKTFKEGDHLPLAPSVWQAGHKKVQPQPGSIICCFVYGLIEHTGIWLDEHTLIELHGSGLVRAVSTKRFLAGRTGSKIFVACSHDHQVLVEPAMLEKAQQAIYTYREYDLFDNNCHRFVWSCLSGKEESLSSFNDLNQRLAGYFNQSLYWDEAKLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJB2</accession>
    <name>B1KJB2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="4 6">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4331</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="4 6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326910.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4331"/>
    <dbReference type="EnsemblBacteria" id="ACA88584">
        <property type="protein sequence ID" value="ACA88584"/>
        <property type="gene ID" value="Swoo_4331"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4331"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_10_3_6"/>
    <dbReference type="OMA" id="KQRIKLW"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00613"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="8">
        <location>
            <begin position="66"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="240" mass="26752" checksum="D43ACE165E18F250" modified="2008-04-29" version="1" precursor="true">MLLILRSLVLAVMLLLAFVFGGLFCLIRPRHRDNVHMFAKIFSYAAPVLGIKVIVRKANVATTEPCVFLANHQNNFDMFTHTAAVPKGTVSLGKKSLAWVPFFGQIYWLSGNILIDRKNRSRAFETMAQTAKKIKDKCLSIWIFPEGTRSRGKGLLPFKSGAFHTAIEAGVAMVPVLASNQGHIKLNRWNNGVVIIEMMEPIETKGLAKSQVKELSKRIHSMMSTRLTQLDQEASALMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJB7</accession>
    <name>B1KJB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88589">
        <property type="protein sequence ID" value="ACA88589"/>
        <property type="gene ID" value="Swoo_4336"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4336"/>
    <dbReference type="eggNOG" id="ENOG5031EM7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_213952_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="41" mass="4725" checksum="2B344F60BF791628" modified="2008-04-29" version="1">MLEFLRENGKMIIWTTLFFIAIGGGIYYVDMALEAQVQVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJF2</accession>
    <name>B1KJF2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326950.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4371"/>
    <dbReference type="EnsemblBacteria" id="ACA88624">
        <property type="protein sequence ID" value="ACA88624"/>
        <property type="gene ID" value="Swoo_4371"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4371"/>
    <dbReference type="eggNOG" id="ENOG50348JW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1853856_0_0_6"/>
    <dbReference type="OMA" id="RHRQYFE"/>
    <dbReference type="OrthoDB" id="1962380at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="141" mass="16341" checksum="03BF12F82F6BC8F8" modified="2008-04-29" version="1">MLTKLNTCVIACLIFSYPLYLWSTYIDKTILKGSAFEFIIGSSKSEVYENLPLALSKLKGESDKVFIQVKSNEELAGYLASSPDFNVWVNPYFHPIGYAQFASKDEWDFYINASFTNVLKLKFCEGRLCEIYRHRQYFELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL8</accession>
    <name>B1KJL8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibronectin type III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324037.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85691">
        <property type="protein sequence ID" value="ACA85691"/>
        <property type="gene ID" value="Swoo_1399"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1399"/>
    <dbReference type="HOGENOM" id="CLU_679520_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="51"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="405" mass="46031" checksum="E0D34949B99EAE7F" modified="2008-04-29" version="1" precursor="true">MRDMFTRNRWQRAVVSKLSILIGRWIELRGAALVSSILLLFFCGGANAAGGIGSVWATASDDSSISITWSVPSGDYDHVGSNYKVCYRKTPTVNVCGVGPYYEASNSYHATGLSSGTEYKFKVWCYCKKRNWRGKWKDAKWRKIGTYKQSTSPEPEPDVLVSSISVVDVAPGASKFEASIDVEVTYTNPAAFEFVRVCYKKLGNMSSMNSICSKRDQPPISWTSSDHGRGWLDIAPAPSGTIFSFGSLKQCRQYKVVSYAFYDGVDTGLKLGETNVHTPGDCKANKMAVVIVDDYSETILHEYAQMMSHYYDEHLFQHLAMQYDQELFTAQKLMMEEQRVDIVQPKALIEYLVSSDSQVWDRWQQERSLVEQRLTLDAYMQDKYPELYSDILDDLKEPEQQREKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR2</accession>
    <name>B1KJR2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PhnA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YjdM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324081.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1443"/>
    <dbReference type="EnsemblBacteria" id="ACA85735">
        <property type="protein sequence ID" value="ACA85735"/>
        <property type="gene ID" value="Swoo_1443"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1443"/>
    <dbReference type="eggNOG" id="COG2824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125511_0_0_6"/>
    <dbReference type="OMA" id="EGWPQDL"/>
    <dbReference type="OrthoDB" id="1507972at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013991">
        <property type="entry name" value="PhnaA_N_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004624">
        <property type="entry name" value="YjdM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013988">
        <property type="entry name" value="YjdM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013987">
        <property type="entry name" value="YjdM_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF3">
        <property type="entry name" value="PTHR30305:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03831">
        <property type="entry name" value="YjdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08274">
        <property type="entry name" value="YjdM_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00782">
        <property type="entry name" value="PhnA_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhnA_Zn_Ribbon" evidence="2">
        <location>
            <begin position="4"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="192" mass="21439" checksum="80F7E9F9BDC5A306" modified="2008-04-29" version="1">MTRELLKRCDSKCELCGSETKLASFELPDSKGYGDARIMICDTCTGQIQDPSSIDMNHWRCLNDSMWSQVPAVQIMAYRMLKQISAEAWARDLLDMLYLDEHMQAWAEAGIEEVDEDFVPHKDSNGAILEAGDNVVIIKDLNVKGTTFTAKRGTTVRGISLTNNPEHIEGRVNGTRIVILTCFVKKVPAGEE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJV5</accession>
    <name>NUOI_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit I</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoI</name>
        <name type="ordered locus">Swoo_2867</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 2 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 23 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325478.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJV5"/>
    <dbReference type="SMR" id="B1KJV5"/>
    <dbReference type="STRING" id="392500.Swoo_2867"/>
    <dbReference type="EnsemblBacteria" id="ACA87142">
        <property type="protein sequence ID" value="ACA87142"/>
        <property type="gene ID" value="Swoo_2867"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2867"/>
    <dbReference type="eggNOG" id="COG1143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067218_4_3_6"/>
    <dbReference type="OMA" id="RGDLYYT"/>
    <dbReference type="OrthoDB" id="1619561at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01351">
        <property type="entry name" value="NDH1_NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01971">
        <property type="entry name" value="NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_1000143670" description="NADH-quinone oxidoreductase subunit I">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type 1" evidence="1">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type 2" evidence="1">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01351"/>
        </source>
    </evidence>
    <sequence length="171" mass="19419" checksum="BD46024168E81AA3" modified="2008-04-29" version="1">MLSQIRTLITILKHTFTRADTVEYPEQKPYLSPRYRGRIVLTRDPDGEERCVACNLCSVACPVDCISVVKTEKEDGRWEAESFTINFSRCIMCGFCEEACPTHAIQLTPDVEMAEYDRQNLVFEKEHLLISGPGKYHDYNFYKVSGKAINGKGKGEAHNEQSPINVRSLLP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJX4</accession>
    <name>ACKA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetate kinase</fullName>
            <ecNumber evidence="1">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ackA</name>
        <name type="ordered locus">Swoo_2886</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325497.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJX4"/>
    <dbReference type="SMR" id="B1KJX4"/>
    <dbReference type="STRING" id="392500.Swoo_2886"/>
    <dbReference type="EnsemblBacteria" id="ACA87161">
        <property type="protein sequence ID" value="ACA87161"/>
        <property type="gene ID" value="Swoo_2886"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2886"/>
    <dbReference type="eggNOG" id="COG0282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020352_0_1_6"/>
    <dbReference type="OMA" id="KIITCHI"/>
    <dbReference type="OrthoDB" id="537106at2"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000089993" description="Acetate kinase">
        <location>
            <begin position="1"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="208"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="283"/>
            <end position="285"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="331"/>
            <end position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <sequence length="398" mass="43134" checksum="FA5AE7720595FD9C" modified="2008-04-29" version="1">MSNKLVLVLNCGSSSLKFAIIDALTGDDQISGLAECFGLEDAKIKWKVNGVKHDASLGAFSSHREAVEFIVKDVLGAHPEIASQIQAIGHRVVHGGEKFTQSVIIDESVVQGIEDCAALAPLHNPAHLIGIRAAQASFPQLPQVAVFDTAFHQTMPEKAFIYALPYKLYRENSIRRYGMHGTSHLFISREAAKAMGKNIEDSNIICAHLGNGASVTAIKGGKSVDTSMGMTPLEGLVMGTRCGDIDPSIIHHLVDRLGYTLDEVNNLMNKQSGLLGISELTNDCRGIEEGYSEGHKGATLALEIFCYRLAKYIASYTVPLGRLDAVVFTGGIGENSDLIRAKVLNLLEIFNFEVDDERNKAARFGNQGQITTDNGTIAMVIPTNEEWVIAEDAVRLLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK11</accession>
    <name>YCIB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inner membrane-spanning protein YciB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yciB</name>
        <name type="ordered locus">Swoo_2925</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325534.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KK11"/>
    <dbReference type="STRING" id="392500.Swoo_2925"/>
    <dbReference type="EnsemblBacteria" id="ACA87198">
        <property type="protein sequence ID" value="ACA87198"/>
        <property type="gene ID" value="Swoo_2925"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2925"/>
    <dbReference type="eggNOG" id="COG2917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089554_2_0_6"/>
    <dbReference type="OMA" id="AWVNFKL"/>
    <dbReference type="OrthoDB" id="1886685at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00189">
        <property type="entry name" value="YciB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006008">
        <property type="entry name" value="YciB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36917">
        <property type="entry name" value="PTHR36917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04279">
        <property type="entry name" value="IspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00997">
        <property type="entry name" value="ispZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000098898" description="Inner membrane-spanning protein YciB">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00189"/>
        </source>
    </evidence>
    <sequence length="182" mass="20892" checksum="FE184854C1CCBB06" modified="2008-04-29" version="1">MKQLLDFLPLVIFFAVYKMYDIYIASGALIAATALQLIVTYALYKKIEKMHLITFVMVTFFGTLTLIFHDDAFIKWKVTVVYALFAIALAVSQLLNKPILKSMLGKELVVADKIWAHVTWYWVSFFVACGLVNIYVAFSLSQETWVNFKVFGLTALTLINTVITVVYLFKNMPEEHKKELNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK34</accession>
    <name>B1KK34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4413</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326991.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4413"/>
    <dbReference type="EnsemblBacteria" id="ACA88665">
        <property type="protein sequence ID" value="ACA88665"/>
        <property type="gene ID" value="Swoo_4413"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4413"/>
    <dbReference type="eggNOG" id="COG1459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035032_2_2_6"/>
    <dbReference type="OMA" id="FSRQMYS"/>
    <dbReference type="OrthoDB" id="1268170at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="69"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="273"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="406" mass="45256" checksum="2ABDFD53318DA6E0" modified="2008-04-29" version="1">MPVYKYRGRDAQGQQVTGVVDAATENAAADQLMSRSVIPLELNESKEKASFTLASLFKGKVSLDELQIFSRQMYSLTRSGIPILRAIAGLSETTHSQRMKDALNDISEQLTSGRPLSSAMNHHPDVFDSLFVSMVHVGENTGKLEDAFIQLSGYIEREQETRRRIKAAMRYPIFVLMAITLAMVILNIMVIPKFAEMFSRFGADLPWATKLLIGTSNLFVNYWPVMLVAAVGTFIGIRYWHSTEKGEKQWDKWKLHIPAVGSIIERSTLSRYCRSFSMMLSAGVPMTQALSLVADAVDNAYMHDRIVAMRRGIESGDSMLRVCNQSHLFTPLVLQMVAVGEETGQIDQLLNDAADFYEGEVDYDLKNLTAKLEPILIGFVAGIVLILALGIYLPMWDMLNVVKGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK78</accession>
    <name>B1KK78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327035.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88709">
        <property type="protein sequence ID" value="ACA88709"/>
        <property type="gene ID" value="Swoo_4457"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4457"/>
    <dbReference type="HOGENOM" id="CLU_2755642_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="70" mass="8165" checksum="5019D8066D0270B3" modified="2008-04-29" version="1">MHKSGYGSHSQVQRYKVQSKVPEGFAHHNHKEVVRLRLIKWGLLFLVVIWEIVGNIEMLGVEDRKIGKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC0</accession>
    <name>B1KKC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324106.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85760">
        <property type="protein sequence ID" value="ACA85760"/>
        <property type="gene ID" value="Swoo_1472"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1472"/>
    <dbReference type="HOGENOM" id="CLU_2234743_0_0_6"/>
    <dbReference type="OrthoDB" id="2032367at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="11779" checksum="B791BB20523FF368" modified="2008-04-29" version="1">MNRIIYTSFFNLLLLSFSVESLERITGYVKVLEPTYMPNTISFSMSAGTASCPAGSWLKWSKTEDNNKVAFSTLMAALMSGKKINLYFLDNDTTCTAQFLHLLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC6</accession>
    <name>B1KKC6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324112.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1478"/>
    <dbReference type="EnsemblBacteria" id="ACA85766">
        <property type="protein sequence ID" value="ACA85766"/>
        <property type="gene ID" value="Swoo_1478"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1478"/>
    <dbReference type="eggNOG" id="ENOG502ZGYS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169696_0_0_6"/>
    <dbReference type="OMA" id="FATIGHV"/>
    <dbReference type="OrthoDB" id="2164164at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764994" evidence="1">
        <location>
            <begin position="23"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12226" checksum="0DFCEE68738F073B" modified="2008-04-29" version="1" precursor="true">MLRIVMITIAVTCTLFPFLVNAAAGWSGRAEVTGIYTLNESTALIKLSTFSNPNSCQINSSGDVRINPSVDKNWMSMFLAAYISGKPVDVYVSAACTGVWTGTSYATVGHVRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD2</accession>
    <name>B1KKD2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324118.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1484"/>
    <dbReference type="EnsemblBacteria" id="ACA85772">
        <property type="protein sequence ID" value="ACA85772"/>
        <property type="gene ID" value="Swoo_1484"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1484"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068226_1_2_6"/>
    <dbReference type="OMA" id="YRHHIGL"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="231" mass="26673" checksum="AB8574E679C7FE2C" modified="2008-04-29" version="1">MPRKPRFYAPDITCHIVQRGNNRSACFFNDDDFKIYINALSDALIQYNVKLHAFVLMTNHVHLLMTPSTTEGISQVMQSIGRTYVSTINRLYQRTGTLWEGRHKACLIDSEAYFIACLRYIELNPVRANMVKHPSEYPWSSYQFHGAGKQIACLTPHPLYQQLGSTPELRQHQYRELFNTELPPEQVHTIRNCLNHNFPLGSDKFRADIEAHLNVRFGHLAPGHPNKPKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF3</accession>
    <name>B1KKF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324139.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1505"/>
    <dbReference type="EnsemblBacteria" id="ACA85793">
        <property type="protein sequence ID" value="ACA85793"/>
        <property type="gene ID" value="Swoo_1505"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1505"/>
    <dbReference type="eggNOG" id="ENOG5031F6Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2208270_0_0_6"/>
    <dbReference type="OMA" id="KLAPFSC"/>
    <dbReference type="OrthoDB" id="2027890at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12148" checksum="D32805495637DB59" modified="2008-04-29" version="1" precursor="true">MNIVIGTAVVVLWLGCLALLLCSKHQRLLKKPLSKEASTLGFVTSFMLSIWLLMAEYNLVAASLMVLVFTLAIWLSQVLLLGHVKLKLAPFSCVNLAFWLAVAQLGGQHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL0</accession>
    <name>B1KKL0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325563.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2954"/>
    <dbReference type="EnsemblBacteria" id="ACA87227">
        <property type="protein sequence ID" value="ACA87227"/>
        <property type="gene ID" value="Swoo_2954"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2954"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_5_0_6"/>
    <dbReference type="OMA" id="GAWGTNC"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="12"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="23683" checksum="5D00C5B8DCAEDF27" modified="2008-04-29" version="1">MKYQIIPVTPFQQNCSLVWCDETMKAAVIDPGGDIDRILSEVKKLGVSLEKVFLTHGHIDHVGGAKQLSEQLNIPIIGPHKADIFWLDNLVEQSQHFGLKACEPFTSTQYLEDGDSVTIGNLTLQVLHCPGHTPGHVVFFCEKAKTAWVGDVLFHGSVGRTDFPQSNHDDLILSITKKLWPLGRDVEFIPGHGPISTFGSERDQNPFVADQLFG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL03</accession>
    <name>RL33_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmG</name>
        <name type="ordered locus">Swoo_4559</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_011494790.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL03"/>
    <dbReference type="SMR" id="B1KL03"/>
    <dbReference type="STRING" id="392500.Swoo_4559"/>
    <dbReference type="EnsemblBacteria" id="ACA88809">
        <property type="protein sequence ID" value="ACA88809"/>
        <property type="gene ID" value="Swoo_4559"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4559"/>
    <dbReference type="eggNOG" id="COG0267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190949_1_1_6"/>
    <dbReference type="OMA" id="GTGFYYT"/>
    <dbReference type="OrthoDB" id="2034291at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000356668" description="50S ribosomal protein L33">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <sequence length="57" mass="6753" checksum="BEBA695E83C8AA5D" modified="2008-04-29" version="1">MAKSKGNREKIKLVSSAKTGHFYTTEKNKRNMPEKMEIKKFDPVIRQHVMYKEAKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL27</accession>
    <name>B1KL27_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="9">Kdo transferase</shortName>
            <ecNumber evidence="3 9">2.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 9">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0067</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="3 9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322717.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0067"/>
    <dbReference type="CAZy" id="GT30">
        <property type="family name" value="Glycosyltransferase Family 30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84368">
        <property type="protein sequence ID" value="ACA84368"/>
        <property type="gene ID" value="Swoo_0067"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0067"/>
    <dbReference type="eggNOG" id="COG1519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036146_2_0_6"/>
    <dbReference type="OMA" id="FIKYEFW"/>
    <dbReference type="OrthoDB" id="1163086at2"/>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_N" evidence="10">
        <location>
            <begin position="34"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="421" mass="46023" checksum="E78E3CAC15D0FD57" modified="2008-04-29" version="1">MNRFLYSVLLYLLLPLLVLYLAFRAIKSPDYRGRWGERFGLSKLKQSDLLIHSVSMGETLAAIPLIKAVQQQYPQMSITVTTTSPTGSAEVIKALGSSVQHCYLPFDISVCVKRFLNQVSPKQIIIMETELWPNLVHQASKLGVKIMLANARLSQKSADQYQKRITLSLPMLQSLDMIAAQSQQAAERFVALGVSPDKVKVCGSLKFDLTIPAEKLVQARALRELWRDNNAPIWVAGSVHPGEFDAMLKAHKRLLLENPDALLIMVPRHPEQFNTAAEQITASGLSLARRSQQDEVSATTQVLLGDTMGELLTFYGAADQAFVGGTLIDNGGHNPLEPAALGLPVYVGPNHWDFAEIAGLLNDAGALKVIASGEELATELLAKFHDKPTYQAASEAGLRVVDANKGALKQQFELACTLIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL89</accession>
    <name>B1KL89_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Conserved hypothetical 3-methyladenine DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0129"/>
    <dbReference type="EnsemblBacteria" id="ACA84430">
        <property type="protein sequence ID" value="ACA84430"/>
        <property type="gene ID" value="Swoo_0129"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0129"/>
    <dbReference type="eggNOG" id="COG2818">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239284_0_0_6"/>
    <dbReference type="OMA" id="MLAHTVN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="26925" checksum="CDC8D75DE5C31E34" modified="2008-04-29" version="1">MFECQYKNMSQLESFSTIYQRASERKGGDESLESLLTSSLTPDEIGQYKDAELLSEMSKKVFQSGFIWRIVENKWSAYEEAFFGFEPHKVLMLSPEQLQERASDPNLIRHMKKTMAIYDNALMTHDIAREHGSLAEYIANWPSEEITQLWAVLKRRGTRLGGNTGPYFLRAIGKDTFLLTGDVQGYLTSHKLVDFGFSSKSGLKQVQGVFNTWQQQSGRSLADISRVLACSVGDNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA7</accession>
    <name>B1KLA7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutathione-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62632"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="EC" id="1.11.1.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.27" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322797.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0147"/>
    <dbReference type="EnsemblBacteria" id="ACA84448">
        <property type="protein sequence ID" value="ACA84448"/>
        <property type="gene ID" value="Swoo_0147"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0147"/>
    <dbReference type="eggNOG" id="COG0678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072440_1_2_6"/>
    <dbReference type="OMA" id="GYINHPK"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PTHR10430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="2"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="16818" checksum="DFE919C847000AB0" modified="2008-04-29" version="1">MIKQGERVPDGTMLGELTNEGMLTHCVTDLFAGKKVVLFAVPGAFTPTCSQSHLPGFVVLADQFKAKGVDLIACVSVNDAFVMKAWGDSQNASEVMMLADGDASFTKAIGLQVDTAGFGGIRSQRYAMVLEDGVVTDLNVEAPKMFEVSKAEVILDLL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB1</accession>
    <name>DER_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">der</name>
        <name type="synonym">engA</name>
        <name type="ordered locus">Swoo_1548</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324182.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLB1"/>
    <dbReference type="SMR" id="B1KLB1"/>
    <dbReference type="STRING" id="392500.Swoo_1548"/>
    <dbReference type="EnsemblBacteria" id="ACA85836">
        <property type="protein sequence ID" value="ACA85836"/>
        <property type="gene ID" value="Swoo_1548"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1548"/>
    <dbReference type="eggNOG" id="COG1160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016077_6_2_6"/>
    <dbReference type="OMA" id="KFRFLEY"/>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="chain" id="PRO_1000099160" description="GTPase Der">
        <location>
            <begin position="1"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G 1">
        <location>
            <begin position="3"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G 2">
        <location>
            <begin position="200"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="KH-like" evidence="1">
        <location>
            <begin position="374"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="56"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="118"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="206"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="253"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="318"/>
            <end position="321"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="488" mass="54624" checksum="5A5C19F70BAABE50" modified="2008-04-29" version="1">MIPVVALVGRPNVGKSTLFNRLTRTRDALVADYPGLTRDRKYGRAHLSGYEFIVVDTGGIDGTEEGIETHMAEQSMAAIEEADVVLFLTDARAGLTAADQAISEHLRRREKTTFVVANKVDGIDADSACAEFWALGLGEVYQMAAAQGRGVTNMIEYALAPYAEALGLNRDGDDEEEKEEREYTEEEAEAEQTRLQDLPIKLAVIGKPNVGKSTLTNRILGEERVVVYDAPGTTRDSIYIPMERDGREYVLIDTAGVRRRSKVNETVEKFSVIKTLKAVEDCNVVLLIVDAREGIAEQDLGLLGFALNAGRALVIAVNKWDGIDQDIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHLFESVQEAYESATRRVSTSMLTRIMQMAQDDHQPPMVNGRRVKLKYAHAGGYNPPIVVVHGNQVKKLPDSYKRFMMNYYRRSLKVMGTPIQVRFQDGDNPFEGMNTKKLTVSQERRRKRMMTHIKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLJ4</accession>
    <name>B1KLJ4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar biosynthesis protein FlhF</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flagella-associated GTP-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_1633</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324265.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1633"/>
    <dbReference type="EnsemblBacteria" id="ACA85919">
        <property type="protein sequence ID" value="ACA85919"/>
        <property type="gene ID" value="Swoo_1633"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1633"/>
    <dbReference type="eggNOG" id="COG1419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_11_5_6"/>
    <dbReference type="OMA" id="FFAADMR"/>
    <dbReference type="OrthoDB" id="1162441at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020006">
        <property type="entry name" value="FlhF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF3">
        <property type="entry name" value="PTHR43134:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03499">
        <property type="entry name" value="FlhF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="249"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="12">
        <location>
            <begin position="250"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="103"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="467" mass="51234" checksum="961FA5A94FDE1623" modified="2008-04-29" version="1">MKIKRFLAKDMRTALAQVKETLGSDAVIMSNKKVTGGIEIVAAVDYDEPKPNLQKAPKTPATPSFMDLAEEKISLGFKRPVRTETKANPAPAADSLQALLERQQSRVNQQATNKSAELEMPDWAKGLKAPEVKKAAPEVEPQQYAQRNHGNSKANSGSNQEMDAMREELASLRNLLTHQVTSLLSEQKSRTNPVGAMLESKLLEAEFSPMVATKLSDLSEHYQPAELVKALPRCLANMLDNQGDDIVRQGGVVAFVGPTGVGKTTTVAKLAARFAAHHGSDQVALITTDHYRIGAFEQLATYGKIMGCPVKQAHDLNELEQILYQFRNRKLVLIDTAGMGQRDLRLFQQLDNLAANSRLPIRSYLVLSATGQRRVLEDAVAQFKRIPLSGAVLTKLDESVSLAPALSVLIQSGLPLSYVTDGQRVPEDMQVADTLALANKALSVLNRKEQVIEQNSERSEERAYAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLJ8</accession>
    <name>B1KLJ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Protein phosphatase CheZ</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Chemotaxis protein CheZ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CheZ family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324269.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1637"/>
    <dbReference type="EnsemblBacteria" id="ACA85923">
        <property type="protein sequence ID" value="ACA85923"/>
        <property type="gene ID" value="Swoo_1637"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1637"/>
    <dbReference type="eggNOG" id="COG3143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080718_0_0_6"/>
    <dbReference type="OMA" id="EGPQIHA"/>
    <dbReference type="OrthoDB" id="1206193at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050920">
        <property type="term" value="P:regulation of chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007439">
        <property type="entry name" value="Chemotax_Pase_CheZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04344">
        <property type="entry name" value="CheZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002884">
        <property type="entry name" value="CheZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="site" description="Enhances dephosphorylation of CheY-P" evidence="8">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR002884-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="27431" checksum="28E7BD7CFE4FAF75" modified="2008-04-29" version="1">MQATTSGLISLEQASKLVDLLTQGEQEQADDLVREIATPIQKELFDEVGRLTRQLHSAIVDFQVDDRLVTLASTEIPDAKERLNYVIDMTEQAANKTMDAVEECLPLADVLTTNIQSVKPKWAKLMKRDIELTEFKKLCHDVEQFVEQSEQDSIRLKELLNQILLAQDFQDLTGQIIRRVIDLVREVENNLVSMLTVFGEQSSVDSSPTSETGIEAEGPIVNAEEREDVVAGQDEVDDLLSSLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK5</accession>
    <name>B1KLK5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325638.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3031"/>
    <dbReference type="EnsemblBacteria" id="ACA87302">
        <property type="protein sequence ID" value="ACA87302"/>
        <property type="gene ID" value="Swoo_3031"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3031"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024570_0_1_6"/>
    <dbReference type="OMA" id="RYFRATD"/>
    <dbReference type="OrthoDB" id="736429at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01467">
        <property type="entry name" value="vWA_BatA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033881">
        <property type="entry name" value="vWA_BatA_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="84"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="330" mass="37032" checksum="7E237AE8EBD2A8FB" modified="2008-04-29" version="1">MLTLAWAWLLLLLPLPLIFRKKQQDVEISGHLHLPGIAQDGKQEMEQSPSSRKTYWVIWILLVIAVARPLWMGDPIELPSKGRDLMVAVDLSGSMQIEDMVLDGKAVNRFIMVQSVVSDFIERRKGDKLGLILFADHAYLQAPLTQDRRSVAQFLKEAQIGLVGKQTAIGEAIALSVKRFDLVDESNRILVLLTDGSNNSGSISPEQAADIAAKRGIKIYSIGVGADVMERRTLFGKERVNPSMDLDEEQLTSLAQTTGGRYFRARNAQELEQIYQEIDKLEPISRDQVSYRPQSELFYLPLAAALIVSILIALAQLPLMRRLNIRWGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM11</accession>
    <name>B1KM11_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327215.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4641"/>
    <dbReference type="EnsemblBacteria" id="ACA88891">
        <property type="protein sequence ID" value="ACA88891"/>
        <property type="gene ID" value="Swoo_4641"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4641"/>
    <dbReference type="eggNOG" id="COG1222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_21_15_6"/>
    <dbReference type="OMA" id="MWIGNSE"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="199"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="49613" checksum="F76A8B93B25340AE" modified="2008-04-29" version="1">MDNNYINSMEQALSLSPDNFILRITLIQALYEHQQLSTALSLLKEVESCQVEQELHQILAAKIFIESGDGENALLFLSSNLPEVKILKAKAYQILNEFSLAREFYVEAVKENSSLEDIDFARELRVAKDALDNSKRIKLTVVANDDTDAVEVTRLIKPREEVISFSEVGGLADVKKQIRKKIITPFQKPSLFQRFKKKVGGGILLFGPPGCGKTLLARATAGECNATFINVVISDILDMYIGESEKKLHAIFEQARQNTPSVIFFDEIESLAAKRQHTREATSAKLVSQFLSELDGFAQNNHGVLILGATNVPWALDPAFRRPGRFDRVVFIAPPDVDARTDILKGLLKDRPGGESVDAQKIARLTSGFSGADLMNLVETAVDEAIDHSIESGEEVPLNQTFVKEALKEVNPTTLEWLTMARNYAKYANDSGQYNEVLAFLRKHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM24</accession>
    <name>B1KM24_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Formate-dependent nitrite reductase complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4654</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Possible subunit of a heme lyase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CcmH/CycL/Ccl2/NrfF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327228.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4654"/>
    <dbReference type="EnsemblBacteria" id="ACA88904">
        <property type="protein sequence ID" value="ACA88904"/>
        <property type="gene ID" value="Swoo_4654"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4654"/>
    <dbReference type="eggNOG" id="COG3088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107187_0_0_6"/>
    <dbReference type="OMA" id="MIAADMR"/>
    <dbReference type="OrthoDB" id="1984854at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005616">
        <property type="entry name" value="CcmH/CycL/Ccl2/NrfF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038297">
        <property type="entry name" value="CcmH/CycL/NrfF/Ccl2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017565">
        <property type="entry name" value="For-dep_Cytc_NO2Rdtase_NrfF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03918">
        <property type="entry name" value="CcmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03147">
        <property type="entry name" value="cyt_nit_nrfF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011023737" description="Formate-dependent nitrite reductase complex subunit" evidence="5">
        <location>
            <begin position="25"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="18467" checksum="7931B7847D3CAB26" modified="2008-04-29" version="1" precursor="true">MIKYMVQICSALLLSLTLISGAVATPVDTYEFKSMDNQKRALELAHSLRCPQCQNQNLIDSNSPVAQDLRLEVYQMVDAGKDDDEVIEFMTSRYGEFVLYKPRMEAKTYALWLGPVALLMFGLFIGFMFIRKQRITEVDEQEISVEEQKELDKLLKRDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM54</accession>
    <name>B1KM54_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0166</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322816.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0166"/>
    <dbReference type="EnsemblBacteria" id="ACA84467">
        <property type="protein sequence ID" value="ACA84467"/>
        <property type="gene ID" value="Swoo_0166"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0166"/>
    <dbReference type="eggNOG" id="COG0643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000650_3_6_6"/>
    <dbReference type="OMA" id="EPEHQID"/>
    <dbReference type="OrthoDB" id="305000at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="8">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="329"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="7">
        <location>
            <begin position="534"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="4">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="677" mass="75055" checksum="98A788BC0C4B13E9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ6</accession>
    <name>B1KMJ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1709"/>
    <dbReference type="EnsemblBacteria" id="ACA85994">
        <property type="protein sequence ID" value="ACA85994"/>
        <property type="gene ID" value="Swoo_1709"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1709"/>
    <dbReference type="eggNOG" id="COG1434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053514_0_1_6"/>
    <dbReference type="OMA" id="LWFTRWQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="83"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="264" mass="29449" checksum="73D4685DD58D67BF" modified="2008-04-29" version="1">MLDTMFWLKKIISQLFMPVPLTVLLLLVAMVLLRNRKLVRSLLSLAIVLLVFLSSTPGSNLLSSPLENKYSVNSNTIPKGCLVMVLGSGHDESISGTAVQKLSSTALARLSEGIRQYNLGSDCKLVVSGWSGGEGTLSHAEVMAEAAIELGIDNERIIRFPLARDTIEEAEFLKWEIGNYPFRLVTSASHMPRSMAIFQNIGLAPQAAPTDFMTRQGRWWRLDAENLWSSQRAIHEYLGRLWFKIKYENDGTMNNASTPARESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMK8</accession>
    <name>B1KMK8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1721</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1721"/>
    <dbReference type="EnsemblBacteria" id="ACA86006">
        <property type="protein sequence ID" value="ACA86006"/>
        <property type="gene ID" value="Swoo_1721"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1721"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_19_3_6"/>
    <dbReference type="OMA" id="LYCVQPM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="31"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="434" mass="47993" checksum="171C0C5A3FBAAA0A" modified="2008-04-29" version="1">MTANTHQVMNSTILIEPEAHTSLVYRSEVRLIWSLSIASIVVYINLYLVQGILPLIANRFDVAVSHGTLLLSVTSFSMAFSLLFYAVLSDRIGRRTPLLISLYLLLLSDLLMVFVADFSQLVTLRLLQGVLLAAVPAIAMAYFKDELSKAAMLKAGAIYIAANSLGGIAGRLIGGALSLHFPWQEVICVILLVSFIGVVTVHCLLPAKGKSRHLPSHLFAATKPTTWYSSLYCDLTGFWHHLKDSKLRSIYLVGGLAFLVMVNQFSYIQLHLMSSPFHWGRFQVTLIFLCYLSGTLASLYSSRWIGRFGRARLFNLAILAMFLGGLVTLLNTTLAICIGFLMSSFGFFLLHSGCNAWVAQRARVHRAKATALYLCCYYLGASLGGPYLLPFWQHWGWSGVVAASSIVLLVLAWVLHRLTQASSDEVARVDFVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ4</accession>
    <name>B1KMQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved hypothetical methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325768.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3161"/>
    <dbReference type="EnsemblBacteria" id="ACA87432">
        <property type="protein sequence ID" value="ACA87432"/>
        <property type="gene ID" value="Swoo_3161"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3161"/>
    <dbReference type="eggNOG" id="ENOG502ZAVQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_696278_0_0_6"/>
    <dbReference type="OMA" id="AQSPEMM"/>
    <dbReference type="OrthoDB" id="1419263at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767215" evidence="2">
        <location>
            <begin position="23"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="393" mass="44269" checksum="C6C31C8C3D1D175D" modified="2008-04-29" version="1" precursor="true">MKALLRLSVMALLGMLTTACSLLEVKLESGIEPLPQEQLNMRVFSRDFSSSFYSKVEQTADKIALLHKDEADAIYIHSNSLMWKIYSEQALQRTIFQASPVAAMVDTWALTAQMTEFYETGAGKALFGSDQALAVEVSRSLQVQFENTIKGFVKPGEFDQNKAFIEQYVDKNPLTEMTFSRHSAFNDWLTFRGINEFEAVTTFGSVPEVMSDISDRMAMIAEQMPKILGWKAELYALHSNINAAEIQDTLANISDTSAKFRELMAQSPEMMQALAVDMRRELSPLLQQLSDSTDNKLAQLSVERQALELMVKNERLALEEMVSRERVEAAANLDEISKHTVEVVFQELTKTLKSLILYFVLFLIVVFFAPLGLGVWLGKRMESKRSVKPAKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN01</accession>
    <name>B1KN01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNP-1 like RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327276.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4708"/>
    <dbReference type="EnsemblBacteria" id="ACA88958">
        <property type="protein sequence ID" value="ACA88958"/>
        <property type="gene ID" value="Swoo_4708"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4708"/>
    <dbReference type="eggNOG" id="COG0724">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110278_0_0_6"/>
    <dbReference type="OMA" id="FDFQERT"/>
    <dbReference type="OrthoDB" id="2029304at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="66"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="17115" checksum="606655CE74AF88AE" modified="2008-04-29" version="1" precursor="true">MQKPFLIVLIIAIVGAFAFTQFADLNAAIAFFTGAIIASVVFALQGKSSPAANNATSVEQYTGPTMTLYVGNLPYRVHEGEVKELFGKYGPVNSVRLVRDRKTGRRKGFGFIEMSEAGAKKAMNKLNEFDFQERTLKVREAKSQDADKSERQEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN38</accession>
    <name>B1KN38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327312.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4745"/>
    <dbReference type="EnsemblBacteria" id="ACA88995">
        <property type="protein sequence ID" value="ACA88995"/>
        <property type="gene ID" value="Swoo_4745"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4745"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_44_1_6"/>
    <dbReference type="OMA" id="YEPSIWL"/>
    <dbReference type="OrthoDB" id="2063007at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="77" mass="8797" checksum="0E080A0AF781C337" modified="2008-04-29" version="1">MKNRLKVLRAEQDWTQADLAEKLDVSRQTVNAIEKGKYDPSLPLAFKLARLFDTPIEAIFDDEVRIDSDKSMLSLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN71</accession>
    <name>B1KN71_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322917.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0267"/>
    <dbReference type="EnsemblBacteria" id="ACA84568">
        <property type="protein sequence ID" value="ACA84568"/>
        <property type="gene ID" value="Swoo_0267"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0267"/>
    <dbReference type="HOGENOM" id="CLU_2773605_0_0_6"/>
    <dbReference type="OrthoDB" id="2213354at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="69" mass="7774" checksum="D3DC7C51D077B8C3" modified="2008-04-29" version="1">MTKKMSAARKAAESTIRHEDLVDAIENFGKKHGLDVEATEGNDPRGDVRVSRKDYAKLESLMDEKLNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF4</accession>
    <name>B1KNF4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dual specificity protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324377.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1746"/>
    <dbReference type="EnsemblBacteria" id="ACA86031">
        <property type="protein sequence ID" value="ACA86031"/>
        <property type="gene ID" value="Swoo_1746"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1746"/>
    <dbReference type="eggNOG" id="COG2453">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1685390_0_0_6"/>
    <dbReference type="OMA" id="AYYLMEN"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="1">
        <location>
            <begin position="78"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="17087" checksum="27123B09953C6F02" modified="2008-04-29" version="1">MQHLFWLVEDKVAGRSGPNKDMWDLNEIKSAGIGAILSVNGGEDCDLAAIKQAELAYACIPFSSNIPPTEDDLGICVEQLPKALAFIRDCEAKDLPVLIHCRSGKDRTGLLMAYYLMENGAAPLHAVSQVRAVRDIAFSAEGWDQFAFDVLYALQD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNG3</accession>
    <name>QUEA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="1">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">queA</name>
        <name type="ordered locus">Swoo_1755</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the QueA family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324386.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNG3"/>
    <dbReference type="SMR" id="B1KNG3"/>
    <dbReference type="STRING" id="392500.Swoo_1755"/>
    <dbReference type="EnsemblBacteria" id="ACA86040">
        <property type="protein sequence ID" value="ACA86040"/>
        <property type="gene ID" value="Swoo_1755"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1755"/>
    <dbReference type="eggNOG" id="COG0809">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039110_1_0_6"/>
    <dbReference type="OMA" id="YSYGDGM"/>
    <dbReference type="OrthoDB" id="368001at2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000094817" description="S-adenosylmethionine:tRNA ribosyltransferase-isomerase">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <sequence length="345" mass="38605" checksum="78C5FBF003A19D6E" modified="2008-04-29" version="1">MRVTDFSFELPDELIARYPMPERTSSRLLSLEGNSGKLGDNQFTDILDMVNPGDLMVFNNTRVIPARLFGQKETGGKLEILVERMLDDKRILAHVRSSKSPKVNTKVCLDGGYEMTMLARHDALFELELNDEKTILEVLEKVGHMPLPPYIDRPDEDADKERYQTVYNDAPGAVAAPTAGLHFDDALLNRLKEKGVDTAFVTLHVGAGTFQPVKVDDVLDHKMHSEWAEVSQEVVDKIAHTKAHGGRVIAVGTTSVRSLESAAKASEDELQPFCRDTDIFIYPGYEFKVVDAMVTNFHLPESTLIMLLSAFAGFDEVKNAYQHAIAQKYRFFSYGDAMFVTKKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNM5</accession>
    <name>B1KNM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA internalization-related competence protein ComEC/Rec2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1818</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324448.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1818"/>
    <dbReference type="EnsemblBacteria" id="ACA86102">
        <property type="protein sequence ID" value="ACA86102"/>
        <property type="gene ID" value="Swoo_1818"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1818"/>
    <dbReference type="eggNOG" id="COG0658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010363_3_0_6"/>
    <dbReference type="OMA" id="ARYNPWR"/>
    <dbReference type="OrthoDB" id="1796527at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030420">
        <property type="term" value="P:establishment of competence for transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07731">
        <property type="entry name" value="ComA-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035681">
        <property type="entry name" value="ComA-like_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004797">
        <property type="entry name" value="Competence_ComEC/Rec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025405">
        <property type="entry name" value="DUF4131"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13567">
        <property type="entry name" value="DUF4131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00361">
        <property type="entry name" value="ComEC_Rec2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="7">
        <location>
            <begin position="519"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="765" mass="85510" checksum="1EA721FD34EC5CC9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY7</accession>
    <name>B1KNY7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4769</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327335.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4769"/>
    <dbReference type="EnsemblBacteria" id="ACA89018">
        <property type="protein sequence ID" value="ACA89018"/>
        <property type="gene ID" value="Swoo_4769"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4769"/>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010186_7_0_6"/>
    <dbReference type="OMA" id="MTGAMVP"/>
    <dbReference type="OrthoDB" id="651103at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="187"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA89018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="414" mass="44695" checksum="C8CA9BB8701B3CA0" modified="2008-04-29" version="1">MPTKADPCSQPSLMHPDEAIIRLLEQVAPLDDSEVVQLPHALGRVLAEDLASSIDLPPFNNSAMDGYAFRFDDLAHNESLTLIGQSFAGHPFEGEVKPNTCVRIMTGAPVPNGYDTVQMQEKVEAKEADIFIEAPKAKGANIRYQGEEVKIGGKVLFSGTQIGAAEMGVLATIGVSQLRVTRQVKVAFFSTGDELRPVGSELAPGQIYDSNRYTIQGLLSRANIEWIDLGVIEDDPEAIRQAFRHAASCADMVLTSGGVSVGDADYTKQILDEEGEITFWKLAIKPGKPFAFGHLGKAIFCGLPGNPVSSMVTFYKLVWPLLQKMQGLPQTKPLTLKAKLNGELRKFPGRVEYQRGVLSHNDQGEAEVTITGGQGSGMLTSMSLANCFVILAQEQGNTADGTLVTVEPFNSVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP18</accession>
    <name>B1KP18_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327366.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4800"/>
    <dbReference type="EnsemblBacteria" id="ACA89049">
        <property type="protein sequence ID" value="ACA89049"/>
        <property type="gene ID" value="Swoo_4800"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4800"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_7_0_6"/>
    <dbReference type="OMA" id="WYFHIAD"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="14743" checksum="C699BD670CA1A92B" modified="2008-04-29" version="1">MDAKLIETLVSAEDFTRLRDISGLSPRPIEAARVGLPRSLFGVQVLVHQHVVGMGRVVGDGALNFEIVDVAVDPAYQGRGYGRMLMQAIMEYLERDAPKGAYITLMADVPELYEKFGFKLSRPASEGMFIIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP20</accession>
    <name>B1KP20_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327368.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4802"/>
    <dbReference type="EnsemblBacteria" id="ACA89051">
        <property type="protein sequence ID" value="ACA89051"/>
        <property type="gene ID" value="Swoo_4802"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4802"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183824_0_0_6"/>
    <dbReference type="OMA" id="FAVIERW"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="92" mass="10280" checksum="3B8BC40FDFD140F0" modified="2008-04-29" version="1">MIVRVGEFQAAAGQAEALYQFLLSLAPYIQGSKGCLSYQVLRKEGEVNEFAVIERWDSVEHHQLSVKGFPPEQMQAAMPLFGAAPKGTYYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP86</accession>
    <name>B1KP86_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323005.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84656">
        <property type="protein sequence ID" value="ACA84656"/>
        <property type="gene ID" value="Swoo_0355"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0355"/>
    <dbReference type="eggNOG" id="ENOG5032TQS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_536252_0_0_6"/>
    <dbReference type="OrthoDB" id="1885406at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="508" mass="59972" checksum="96C6997D020D60FE" modified="2008-04-29" version="1">MAKFSFHKEVWLLKDTQWLSDRKLAWEPIEYQLLCESAVNKNQISAMRRYFIKGEWTEGSEYAPSLDTRMRWCPAISRAYFGEMVSEAKTQYETQYLRETLVKSVMKVVPEEFMSLDDWHRRLTLYQWVVDNEVEYTNKQIEFNSFQVRAFPLETSKANRNDFSKLYLHWVADWLHTLNSNQYQGFIILLPFWFTSLRYMDESIFEWDQNVKTLNQLFIYIRHFIPEHSCHAASQAKKEFVTEFLKCVEKYGLSLVRMTELWEEAAQNKEDESVGREVRSLPLTSDNLETRLEDAFYNTYICDYKSKPDPVFIIHEAMESLGLCEQKYNKSDIKLVDISNVLTSEFKSELCHDTVHAYHVCFQLSPFYIGSEKLTVYQNIFVLVDNNNNLKVIMTESSALRNVVCNSRIFSSRRLFLMDTLREEHGLGFKRYLNYTHDDSDPNSIPPEPEEYLTYLKLLDIPFEDKDYSIFIYGAYGLQYGVDDQFKVVDGPSYSDFVSKVIKSGHPQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS6</accession>
    <name>RECA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recA</name>
        <name type="ordered locus">Swoo_3340</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325944.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPS6"/>
    <dbReference type="SMR" id="B1KPS6"/>
    <dbReference type="STRING" id="392500.Swoo_3340"/>
    <dbReference type="PRIDE" id="B1KPS6"/>
    <dbReference type="EnsemblBacteria" id="ACA87609">
        <property type="protein sequence ID" value="ACA87609"/>
        <property type="gene ID" value="Swoo_3340"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3340"/>
    <dbReference type="eggNOG" id="COG0468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040469_3_2_6"/>
    <dbReference type="OMA" id="DYGEQAL"/>
    <dbReference type="OrthoDB" id="1080436at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <feature type="chain" id="PRO_1000114368" description="Protein RecA">
        <location>
            <begin position="1"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="67"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <sequence length="353" mass="37812" checksum="0D18E720455CBFFA" modified="2008-04-29" version="1">MKIDANKEKALNAVLGQIEKQFGKGSIMKLGENRSMDVETISTGSLSLDVALGAGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKVCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQTNTMLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKERDEVVGNETRVKVVKNKIAAPFKQAEFQILYGQGINRTGELVDLGVAHKLVEKAGAWYSYKGDKIGQGRANAGKFLLDNPAIAEEIDTALRGMLLASVEPAVESEVGDENVDLETGEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS9</accession>
    <name>B1KPS9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325947.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3343"/>
    <dbReference type="EnsemblBacteria" id="ACA87612">
        <property type="protein sequence ID" value="ACA87612"/>
        <property type="gene ID" value="Swoo_3343"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3343"/>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029425_0_1_6"/>
    <dbReference type="OMA" id="TMFLIAY"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="47"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="32947" checksum="725B8AB05CE9793E" modified="2008-04-29" version="1">MSWHARIICMVCFFNVGCSFQSERPAPVASVTTPVKTAYTKGALKLDFYYVKQGDTLYSIAWASDNDFLDLANKNKLKKPYTIFPGQKLNLNVTSNVTNTNLTKTPSKNSHKVVPNPTKPKVKQEVTPVLVAKKTQPIPPKKSLDQQQKSAYPVTTGQQDVNSVVHRPKSELPTKVTRWLWPVKGKLIGTFSAKEQGNKGIKVAGNRGDIIKAAADGRVVYAGSALRGYGNLVIVKHSDDYLSAYAHADSILVKEKQFVTIGQTLAKMGNTGTDRVMLHFEIRHHGKSVNPLKYLPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPX1</accession>
    <name>B1KPX1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325989.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87654">
        <property type="protein sequence ID" value="ACA87654"/>
        <property type="gene ID" value="Swoo_3386"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3386"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115862_2_1_6"/>
    <dbReference type="OMA" id="ITHNEKA"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15407" checksum="455375701407CC9E" modified="2008-04-29" version="1">MKFQVINEEVPDLVNTMVEGVRQHLHDQIGDEATQPLTVVAHDDNGELIGGVSGRSIYGNFLIEVVWVDKRYRGTGLGRKLMESAEVQAIGRGCKVSQVDTLSTQAPLFYQKLGFKIVGEIPEFPGSPGRYFLMKILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPX9</accession>
    <name>B1KPX9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Catalase</fullName>
            <ecNumber evidence="11">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_3394</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325997.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3394"/>
    <dbReference type="EnsemblBacteria" id="ACA87662">
        <property type="protein sequence ID" value="ACA87662"/>
        <property type="gene ID" value="Swoo_3394"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3394"/>
    <dbReference type="eggNOG" id="COG0753">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_2_0_6"/>
    <dbReference type="OMA" id="HVWPQKQ"/>
    <dbReference type="OrthoDB" id="1584770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="PTHR11465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="7 10 11" id="KW-0408">Iron</keyword>
    <keyword evidence="5 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 11 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767289" description="Catalase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase" evidence="13">
        <location>
            <begin position="25"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="503" mass="56267" checksum="6B0933E62648407F" modified="2008-04-29" version="1" precursor="true">MDITKKSCLVLSMSLAFSVQAETLTRDNGAPVGDNQNSITAGSNGSVLLQDVQLIQKLQRFARERIPERVVHARGTGVHGEFVASTDLSGLTQAAPFAEKGKVTPVFVRFSTVIHSKGSPETLRDPRGFATRFYSDQGNWDLVGNNLPVFFIRDAIKFPDMVHSLKPSPVTNLQDPNRFFDFFSHEGTATNMLTWVYTNLGTPSSYRKMDGFGVHAYKFINDENQVKYVKFHWKSQQGVEGLRPNEVTKIQGQNFNHLTDDLYSEINKGNYPKWDLKVKVLSPSDLNKFDYNPLDATKMWQDVPETTVGTMTLNRVPGNFFQETEQAAFAPSNLIPGIEPSEDKLLQGRIFSYADTQLYRLGANLSHLPINQAKVTVANHNQEGAGNYGHTSSDVNYQPSTKLALTDDSRYRAVNTKLSGTVQQAVIKKQDNFTQAGVLYRSLSKQDKSDLITNLSGDLGKVEDSNVKHQMLSYFYQADKEFGQRLTKAVNGDLKEVKRRAKS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ39</accession>
    <name>ATPL_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-type ATPase subunit c</fullName>
            <shortName evidence="1">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpE</name>
        <name type="ordered locus">Swoo_4903</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_011639455.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ39"/>
    <dbReference type="SMR" id="B1KQ39"/>
    <dbReference type="STRING" id="392500.Swoo_4903"/>
    <dbReference type="EnsemblBacteria" id="ACA89152">
        <property type="protein sequence ID" value="ACA89152"/>
        <property type="gene ID" value="Swoo_4903"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4903"/>
    <dbReference type="eggNOG" id="ENOG5032S3K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148047_1_0_6"/>
    <dbReference type="OMA" id="QPELMNE"/>
    <dbReference type="OrthoDB" id="2078221at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0138">CF(0)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0446">Lipid-binding</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000184484" description="ATP synthase subunit c">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <sequence length="83" mass="8469" checksum="7321CF678537775E" modified="2008-04-29" version="1">METVLGMTAIAVALLIGMGALGTAIGFGLLGGKFLEGAARQPEMAPMLQVKMFIVAGLLDAVTMIGVGIALFMLFTNPLGAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQS9</accession>
    <name>B1KQS9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA 5-carboxymethoxyuridine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">cmo5U methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmoM</name>
        <name evidence="3" type="ordered locus">Swoo_3417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine = 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54080"/>
            <dbReference type="Rhea" id="RHEA-COMP:13383"/>
            <dbReference type="Rhea" id="RHEA-COMP:13781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:136879"/>
            <dbReference type="ChEBI" id="CHEBI:138053"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326020.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3417"/>
    <dbReference type="EnsemblBacteria" id="ACA87685">
        <property type="protein sequence ID" value="ACA87685"/>
        <property type="gene ID" value="Swoo_3417"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3417"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061533_0_1_6"/>
    <dbReference type="OMA" id="CHGVLEY"/>
    <dbReference type="OrthoDB" id="1431378at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097697">
        <property type="term" value="F:tRNA 5-carboxymethoxyuridine methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02057">
        <property type="entry name" value="tRNA_methyltr_CmoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033664">
        <property type="entry name" value="Cmo5U_methylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="2">
        <location>
            <begin position="48"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="52"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="28644" checksum="E29F305205294082" modified="2008-04-29" version="1">MQDKNFDTLAHKFAKNIYGTPKGDIRAAVVWRDLQLALAELGDRPLRVLDAGGGFGFFSQKLAALGHEVILCDISAEMLSLAQAQIDSAESDLNIRLVHSPIQALTLAEYGQFDLILCHAVAEWLTDARTTLSQLTELLKPGGLFSLMFYNKEAMRFHSLVSGNFDYVAAEFKIKKKVGLTPTHPLFIDDVRGWFDDWNMELVSQSGVRVIHDYLKHCQPQGFDYAKLLEMELTYSQREPYISLGRYVHFIGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU3</accession>
    <name>B1KQU3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3431</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326034.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3431"/>
    <dbReference type="EnsemblBacteria" id="ACA87699">
        <property type="protein sequence ID" value="ACA87699"/>
        <property type="gene ID" value="Swoo_3431"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3431"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_15_3_6"/>
    <dbReference type="OMA" id="YPAGMAT"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07477">
        <property type="entry name" value="Peptidases_S8_Subtilisin_subset"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034202">
        <property type="entry name" value="Subtilisin_Carlsberg-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765134" evidence="6">
        <location>
            <begin position="24"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="126"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="366"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="436"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="607" mass="61255" checksum="10B6F8E3245680ED" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR94</accession>
    <name>B1KR94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324647.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2017"/>
    <dbReference type="EnsemblBacteria" id="ACA86301">
        <property type="protein sequence ID" value="ACA86301"/>
        <property type="gene ID" value="Swoo_2017"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2017"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_4_6"/>
    <dbReference type="OMA" id="YKQPEND"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="86" mass="10021" checksum="C7F823383AF5158B" modified="2008-04-29" version="1">MMKMPMSDDDFEIYPENVPGKYFVKNLCIDCQLCADIAPKNFACNEDEEYHYVIKQPENAEEEAQVIEALEYCPTESIDIFNDEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR95</accession>
    <name>B1KR95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324648.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2018"/>
    <dbReference type="EnsemblBacteria" id="ACA86302">
        <property type="protein sequence ID" value="ACA86302"/>
        <property type="gene ID" value="Swoo_2018"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2018"/>
    <dbReference type="HOGENOM" id="CLU_593010_0_0_6"/>
    <dbReference type="OrthoDB" id="1291134at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="SSF140959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="510" mass="57470" checksum="320E4BA8DD8C50F0" modified="2008-04-29" version="1">METRSQTSDNGDITDTGKSACPVENSTAELTHNSEKELRNALGKIAESYDELHNISVIQQAKNYYQLPLGSYNSTIKAIFQSAEVALQNLIRLTRLASCKIAQDDINSAMKYVKWSRGFHQLLESLGSAAFNIQTYFPAQCVQRTARFSIKDSPTLKEYVFVVSEFESIFEAKFLSKTEKNNLLNTIGLTSHEDVVYSIVHSLRILVHDAVKWESDLTDVMVEPGLPPYNELVATELLKTAIDTANLEAETYYPMFVALHQIPEILSAEVNDHTERAILYVRSEELSLAQEQLSMSVKLMEPLVKAQTVMVDCLATGEYHYLRENLGPASGMHSLAIRQHMFRDLFCSFWKELELWITKGGGSLESKLNEICLARHSDSSNGESYALINTAIQLHQSFQKWRHEHLNMPRNCLGSGGTKSMIGIPDGLDMVKKMRDASNTFPSLKLFYEAMNLKLTSQEQDALLTAHHLADMSLDSQLIELTGHVTREVFPEVQKKDVCPFRSSHPVRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH2</accession>
    <name>B1KRH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324724.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2095"/>
    <dbReference type="EnsemblBacteria" id="ACA86379">
        <property type="protein sequence ID" value="ACA86379"/>
        <property type="gene ID" value="Swoo_2095"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2095"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117621_0_3_6"/>
    <dbReference type="OMA" id="GPCANKV"/>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="68" mass="7176" checksum="BA545E09B8B49FF3" modified="2008-04-29" version="1">MSKGTVKWFNADKGYGFITPEDGGKDLFVHHSEIRSGGGYATLNDGQSVEFDVGEGQKGPCATNVIPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRL0</accession>
    <name>B1KRL0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326108.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3511"/>
    <dbReference type="EnsemblBacteria" id="ACA87775">
        <property type="protein sequence ID" value="ACA87775"/>
        <property type="gene ID" value="Swoo_3511"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3511"/>
    <dbReference type="eggNOG" id="COG1639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048246_1_0_6"/>
    <dbReference type="OMA" id="WDFAPEV"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="22"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="280" mass="30896" checksum="D8D6C950EE19F9AA" modified="2008-04-29" version="1">MSTEHQLLVGLLKKLKADALVLPTLPEVAMRVQEVVSRPDSSPKQVAEIIGQDAAISARMIKVANSALYSRGIKAENVNCAVTRIGLTQIKSIATSAAMEQLFISTNEMVWEVMDEVWGSSIDVTSAACSMLQIYNKTHKGCGLSFDTLTLACLVHNIGALPVLKEAEAHPDMFTSIEQLRALVRKMQGPIGRAVLKSWEFAPEVTEVVERWSDLSYLPDNVGYLDFVRAAAFYTGELRAGIELEERLDLYAKRGLPVSAEELASDEFLEKYHSIKSSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRN4</accession>
    <name>B1KRN4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclic diguanosine monophosphate-binding protein</fullName>
            <shortName evidence="1">c-di-GMP-binding protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Pilz domain-containing protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer in both c-di-GMP-bound and free forms.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326132.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3535"/>
    <dbReference type="EnsemblBacteria" id="ACA87799">
        <property type="protein sequence ID" value="ACA87799"/>
        <property type="gene ID" value="Swoo_3535"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3535"/>
    <dbReference type="eggNOG" id="ENOG5032YUI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146776_0_1_6"/>
    <dbReference type="OMA" id="LGFVCRH"/>
    <dbReference type="OrthoDB" id="2003700at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027021">
        <property type="entry name" value="C-di-GMP_BP_PA4608"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028141">
        <property type="entry name" value="C-di-GMP_BP_PA4608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0973">c-di-GMP</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="2">
        <location>
            <begin position="3"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR028141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="125" mass="14261" checksum="4BA391767E694D5B" modified="2008-04-29" version="1">MDERRQFSRILFNTTANLNQGENMWATKIHDLSLNGALIDKPMDFEPKEGTITLGFSLPDSDIELRMEATLVYSTERLLGLKCFHIDVDSISHLRRMLELNLGDASLLNRELANFIDAHDKPTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRR7</accession>
    <name>B1KRR7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="9" type="ordered locus">Swoo_3568</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3568"/>
    <dbReference type="MEROPS" id="M41.001"/>
    <dbReference type="EnsemblBacteria" id="ACA87832">
        <property type="protein sequence ID" value="ACA87832"/>
        <property type="gene ID" value="Swoo_3568"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3568"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_16_0_6"/>
    <dbReference type="OMA" id="QYGMTER"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="189"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="605"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="622"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="197"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="657" mass="72134" checksum="389966F14DF79A22" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX2</accession>
    <name>B1KCX2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322696.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0046"/>
    <dbReference type="EnsemblBacteria" id="ACA84347">
        <property type="protein sequence ID" value="ACA84347"/>
        <property type="gene ID" value="Swoo_0046"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0046"/>
    <dbReference type="eggNOG" id="COG2346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103526_3_0_6"/>
    <dbReference type="OMA" id="QYWGGPT"/>
    <dbReference type="OrthoDB" id="1697277at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="149" mass="17246" checksum="CD163E5D3C6AAD7E" modified="2008-04-29" version="1">MNWIKKIFQNSPKSPQSEDSVRDPQQSNAYDLIGGEPVIRALAHQFYLQMLQQGRASELLSIHKAPITESEQKLFEFLSGWLGGPGLFEQKYGHPALRARHMPFQIDEEMRDQWLFCMKRAIEIEISHPEHQAAIYQAISTLADHMRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD18</accession>
    <name>B1KD18_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326186.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87853">
        <property type="protein sequence ID" value="ACA87853"/>
        <property type="gene ID" value="Swoo_3589"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3589"/>
    <dbReference type="HOGENOM" id="CLU_2620097_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="78" mass="8898" checksum="0AE1C621D4B93DFA" modified="2008-04-29" version="1">MLYRHGKLVSKRNLILIRLFTIYEIILVATLGALSLIQWISTGSLQASGVISAFLVFQMTVSVLMAYSFWKYRNANKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD86</accession>
    <name>B1KD86_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3659</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3659"/>
    <dbReference type="EnsemblBacteria" id="ACA87921">
        <property type="protein sequence ID" value="ACA87921"/>
        <property type="gene ID" value="Swoo_3659"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3659"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_10_4_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766962" evidence="4">
        <location>
            <begin position="24"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="39"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="484" mass="54127" checksum="3C683BE61B32DC70" modified="2008-04-29" version="1" precursor="true">MKTNKTLLTALLLGLVISTKLNASFSPLKKEESKLKQANVVIIYVDDLGIMDTGIYGSAQYPTPNIDKLANSGVRFTQAYANAANCAPSRASLMTGLTPAEHGILTVGSSERGESQYRKLIPVTNNTELNPDLTTIADLFKQQGYATAVIGKWHLGKTAPTEYGFDTAIAASHLGHPPSYFYPYSKGKRKLIGLEEGGLKDEYLSNRITREAVNYISSQRQPFFLYLPFYAVHTPIEAPKEWVNQHNARQQAGEIKSAAYAAMIANLDRDVGKLLQALDKSGQRENTLVVFASDNGAYDPATSSLPYRGYKSSLFEGGIKIPLVLSWPKQIPPNSQNRTPVQMSDLFLGIKHLLQPKLALHRQDIISLAEQGKEQPERPLYWHAPIYIDQFAPYRGQPNHPYWKHTPAAAIRLGHYKLIHSYETGKQLLFDLDKDSQEKNNLVNQNPEIREKLFKALQQWQESVNAPMVSELNPNYQSQATSHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD96</accession>
    <name>B1KD96_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0438 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326264.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3669"/>
    <dbReference type="EnsemblBacteria" id="ACA87931">
        <property type="protein sequence ID" value="ACA87931"/>
        <property type="gene ID" value="Swoo_3669"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3669"/>
    <dbReference type="eggNOG" id="COG3085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144599_1_0_6"/>
    <dbReference type="OMA" id="DYTIRES"/>
    <dbReference type="OrthoDB" id="1881512at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007335">
        <property type="entry name" value="DUF413"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04219">
        <property type="entry name" value="DUF413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="14457" checksum="4C9C12432584ABF2" modified="2008-04-29" version="1">MSEDSFRFGQKCFIDNINFPRGFRKSGDFTLAESELLSLYGDTLLGLESGLLAPETIEEEHFVRTLTQPHKAKTKIELVWIKYMKLTREPRRFHSLNSTHSYKVPSEIMPAASMKFEEAGQLDANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDC2</accession>
    <name>B1KDC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323270.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0627"/>
    <dbReference type="EnsemblBacteria" id="ACA84923">
        <property type="protein sequence ID" value="ACA84923"/>
        <property type="gene ID" value="Swoo_0627"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0627"/>
    <dbReference type="eggNOG" id="ENOG5033A7N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141656_2_0_6"/>
    <dbReference type="OMA" id="GTACICE"/>
    <dbReference type="OrthoDB" id="2065830at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032720">
        <property type="entry name" value="Cys_rich_CWC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14375">
        <property type="entry name" value="Cys_rich_CWC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="71" mass="7672" checksum="294E4770D7478E22" modified="2008-04-29" version="1">MTQTSATFCPLCRNKNLCAVSANGSIDECWCQTACFPPKAAVKELTDGSSCICQDCLSRIKQELALGLKRV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDN0</accession>
    <name>RLMKL_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase K/L</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">23S rRNA m2G2445 methyltransferase</fullName>
                <ecNumber evidence="1">2.1.1.173</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">rRNA (guanine-N(2)-)-methyltransferase RlmL</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">23S rRNA m7G2069 methyltransferase</fullName>
                <ecNumber evidence="1">2.1.1.264</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">rRNA (guanine-N(7)-)-methyltransferase RlmK</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmL</name>
        <name type="ordered locus">Swoo_2143</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42740"/>
            <dbReference type="Rhea" id="RHEA-COMP:10215"/>
            <dbReference type="Rhea" id="RHEA-COMP:10216"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.173"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(2069) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2069) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43772"/>
            <dbReference type="Rhea" id="RHEA-COMP:10688"/>
            <dbReference type="Rhea" id="RHEA-COMP:10689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.264"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RlmKL family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.173" evidence="1"/>
    <dbReference type="EC" id="2.1.1.264" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324772.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDN0"/>
    <dbReference type="SMR" id="B1KDN0"/>
    <dbReference type="STRING" id="392500.Swoo_2143"/>
    <dbReference type="EnsemblBacteria" id="ACA86427">
        <property type="protein sequence ID" value="ACA86427"/>
        <property type="gene ID" value="Swoo_2143"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2143"/>
    <dbReference type="eggNOG" id="COG0116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014042_2_0_6"/>
    <dbReference type="OMA" id="WIRGYEA"/>
    <dbReference type="OrthoDB" id="307177at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052915">
        <property type="term" value="F:23S rRNA (guanine(2445)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01858">
        <property type="entry name" value="23SrRNA_methyltr_KL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017244">
        <property type="entry name" value="23SrRNA_methyltr_KL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037618">
        <property type="entry name" value="RNA_Mtase_bacteria_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01261">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000366835" description="Ribosomal RNA large subunit methyltransferase K/L">
        <location>
            <begin position="1"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="THUMP" evidence="1">
        <location>
            <begin position="43"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01858"/>
        </source>
    </evidence>
    <sequence length="711" mass="80403" checksum="4FD2AF4ADB5D0F51" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV3</accession>
    <name>B1KDV3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326287.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3695"/>
    <dbReference type="EnsemblBacteria" id="ACA87955">
        <property type="protein sequence ID" value="ACA87955"/>
        <property type="gene ID" value="Swoo_3695"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3695"/>
    <dbReference type="eggNOG" id="ENOG5031EK2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177058_0_0_6"/>
    <dbReference type="OMA" id="QADIYTQ"/>
    <dbReference type="OrthoDB" id="1889542at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766481" evidence="1">
        <location>
            <begin position="22"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11363" checksum="380CDBD223D8D456" modified="2008-04-29" version="1" precursor="true">MKIMTPLALLAASLLPLTASADLVKQQNKAKPMETITVTYREPTDYALYQYTTDMLVNFRLQIQADIYQQARTSIMKMANTTPYMSAMHQAPEQEQNSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDZ6</accession>
    <name>B1KDZ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326330.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87998">
        <property type="protein sequence ID" value="ACA87998"/>
        <property type="gene ID" value="Swoo_3739"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3739"/>
    <dbReference type="eggNOG" id="COG3152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093674_4_1_6"/>
    <dbReference type="OMA" id="WMFTLFN"/>
    <dbReference type="OrthoDB" id="1961299at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008523">
        <property type="entry name" value="DUF805"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34980">
        <property type="entry name" value="PTHR34980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05656">
        <property type="entry name" value="DUF805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12929" checksum="FA482A32BB28DF68" modified="2008-04-29" version="1">MEYFVGGLKKYADFTGRARRKEFWMYTLFYLIFYVLAAFVDSLLGTMIFTAILSLGLLLPTIAIAARRLHDTGRSGWWQLLGLIPLIGAIVLIVFYVQDSIGENEYGANPKGVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE13</accession>
    <name>B1KE13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="ESTHER" id="9gamm-a0j7z6">
        <property type="family name" value="AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88015">
        <property type="protein sequence ID" value="ACA88015"/>
        <property type="gene ID" value="Swoo_3756"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3756"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_540675_0_0_6"/>
    <dbReference type="OMA" id="HVPMKSH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="97"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="504" mass="55428" checksum="6BB098867457DABA" modified="2008-04-29" version="1" precursor="true">MRIDTIYRYMLLMLLVVASTETLSADSWLDKVKSGYKEVENKITTEFSLDDKTEELALAKPLPLDVPANWHYSYFNEPIFNSQMVILEDGVQHRKTIVLVHGLGELGMKDWFNLIPKLAEQYHVIAVDLPGFGLSGVPQGRYTPTNYAKVLNAVLNQYVDSPITLVGHSMGGAISLRFASMYPNSVDKLVLIDVAGVLEKTAFVKHISELPFDESLVPNMLKKTIAQVNDFGSSLVELGTLHDPASDFLHGNDVTWNALLSNSPNINAALSLVEEDFNSAVRNLTVDTSIIWGAKDTVAPIRTAKVLSANIESARLVIIENASHVPMKSHPQEFMVELQHALASKTVKESIVEKGKTDKSQGDLVCDNKANMTYSGNFDAIILNQCTNIKLKEVTATSLEANDSLVEVENLLLVSHRIALKADESVIRITNGVIKGDKAISLSGSRLDLAGVEIIGGEYTIYSDKHSQVVFSICKSESQQFSGLLHGVYELTETTLDELLYSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE37</accession>
    <name>B1KE37_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323370.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0728"/>
    <dbReference type="EnsemblBacteria" id="ACA85023">
        <property type="protein sequence ID" value="ACA85023"/>
        <property type="gene ID" value="Swoo_0728"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0728"/>
    <dbReference type="eggNOG" id="ENOG5031IMM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137423_0_0_6"/>
    <dbReference type="OMA" id="CIMKLAV"/>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="28034" checksum="2B2450D8B50E44FD" modified="2008-04-29" version="1">MKPITNRSQCGAMAPDYLTFSVISLPKKRVKAPYCLLKPVKEKTVFPLFWLCLLACLLLCNTVMAADVSREIRDYYLQQILEGSDHTQDDGATHLGLEFRIKGEGDKFEIGYTSRSNWQLGFEQIALGRDNFLFSELPVLALNEWKSLAQEVGEYEGWGAKLGYRYELTPRLSSSIHLGGFNWKQYSHDNLNQWYGEQSGISPYGGVGLEYTLNANASFRFNWQHFELNSDCFDDFAIRLDYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE55</accession>
    <name>B1KE55_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0746</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323388.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0746"/>
    <dbReference type="EnsemblBacteria" id="ACA85041">
        <property type="protein sequence ID" value="ACA85041"/>
        <property type="gene ID" value="Swoo_0746"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0746"/>
    <dbReference type="eggNOG" id="COG2064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056917_4_1_6"/>
    <dbReference type="OMA" id="ITLRQMD"/>
    <dbReference type="OrthoDB" id="1559784at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="150"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="287" mass="32494" checksum="3F29F68C6676EB65" modified="2008-04-29" version="1">MVNLIVTVFTIAFIFLTISSIRIYRKVPQANREFMDPLSPGLKLIWPLVRLFAFYVSENLSVDYLERISKKLQISGVSYMMTAEQYFAIRILSTLFAVGLATICGLLLDDISIKYLILAGLFGYILPVITLNDLRKKRQALIVKSLPVYLDYLTMSIEAGLNMTGAISQAVERGPSGPLRIEFEKVIRDMRAGMSRAQSFRNMAERVQITEINSLVSALAQAEKTGASLGQTLRVQSDQRRIERFQRAEKKALEAPVKLVFPLIVFIFPVTFMILAFPIAMKFMYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEM3</accession>
    <name>B1KEM3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3779</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326369.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3779"/>
    <dbReference type="EnsemblBacteria" id="ACA88038">
        <property type="protein sequence ID" value="ACA88038"/>
        <property type="gene ID" value="Swoo_3779"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3779"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_133_2_6"/>
    <dbReference type="OMA" id="RWFEDQQ"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="333"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="448"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="409"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="683" mass="76913" checksum="F23AA86827964392" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES6</accession>
    <name>B1KES6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326421.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3832"/>
    <dbReference type="EnsemblBacteria" id="ACA88091">
        <property type="protein sequence ID" value="ACA88091"/>
        <property type="gene ID" value="Swoo_3832"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3832"/>
    <dbReference type="eggNOG" id="ENOG5033MZJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_195979_1_1_6"/>
    <dbReference type="OMA" id="QFRECEN"/>
    <dbReference type="OrthoDB" id="2087478at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="71" mass="7876" checksum="F797E1874C63D0E3" modified="2008-04-29" version="1" precursor="true">MRTLLGMALPLALTVAITGCTNKELYQFGQEQQESQCISEAVSESQINDCKSANKPSYEEYKKEREAVVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF28</accession>
    <name>B1KF28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323526.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0885"/>
    <dbReference type="EnsemblBacteria" id="ACA85179">
        <property type="protein sequence ID" value="ACA85179"/>
        <property type="gene ID" value="Swoo_0885"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0885"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090658_0_0_6"/>
    <dbReference type="OMA" id="HIRLHLY"/>
    <dbReference type="OrthoDB" id="1941611at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="27918" checksum="4046BAA9EDFB75AF" modified="2008-04-29" version="1">MILGTCQFDAHRAQLKNLTTGDEWLLPRAELQVLKLLLASRGSVVEKHKLGAADDEHPALTDSSVTRAVFMLRSFLGAEHEHLIETVKGRGYRLRCETRRRRDKWLTLTWGKPWLVLVILLPFIVLTALHFSENYAGNGPTAPLKTVALSLPSGQKLSLISYSKSKTNNESLLLLIEQLEMGFKQCISTSWQQVYLSLSHDKQVFNITMKGDKLGQSVIRNLKLSDFRQQKQFISQTWLDEVALCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF52</accession>
    <name>B1KF52_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipopolysaccharide assembly protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lapB</name>
        <name evidence="4" type="ordered locus">Swoo_2314</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324935.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2314"/>
    <dbReference type="EnsemblBacteria" id="ACA86593">
        <property type="protein sequence ID" value="ACA86593"/>
        <property type="gene ID" value="Swoo_2314"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2314"/>
    <dbReference type="eggNOG" id="COG2956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059365_1_0_6"/>
    <dbReference type="OMA" id="FWQCPGC"/>
    <dbReference type="OrthoDB" id="1425742at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031235">
        <property type="term" value="C:intrinsic component of the cytoplasmic side of the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008653">
        <property type="term" value="P:lipopolysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046890">
        <property type="term" value="P:regulation of lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00994">
        <property type="entry name" value="LPS_assembly_LapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030865">
        <property type="entry name" value="LapB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="2">
        <location>
            <begin position="21"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_2" evidence="3">
        <location>
            <begin position="352"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="386" mass="44224" checksum="D7088217D19FD557" modified="2008-04-29" version="1">MLEILFLLLPIAAGYGWYMGRRSVRHKQSSDRKKLSRDYFTGLNFLLSNESDKAVDLFISMLDVDDDTIDTHLSLGSLFRKRGEVDRSIRIHQNLIARPSLGNEQRDIAMMELGKDYQAAGFYDRAEEIFLNLVKQEDHSEVAEEHLIDIYQITKDWQKAINIIKTLKRKRQQCFKHNTAHFYCELADEETESSEQVKLLQSAIKLDSNCARALLTLARQYLELGEFAKCIEMLTKLIDADIDLVPDALSTAKQAFIKKGDQVGYCEYLRLALSEGAGASVAVNLAHNLIEQGEHKEAEKLILDGLYRNPTMKSFQHLMQMHVQQAEEGQAKTSLTMLEKLVEQQIKYRPGYRCSECGFPSHSLYWHCPSCKHWGSIKRIRGLDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF58</accession>
    <name>B1KF58_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324941.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2320"/>
    <dbReference type="EnsemblBacteria" id="ACA86599">
        <property type="protein sequence ID" value="ACA86599"/>
        <property type="gene ID" value="Swoo_2320"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2320"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016532_0_0_6"/>
    <dbReference type="OMA" id="DAEYQNT"/>
    <dbReference type="OrthoDB" id="227881at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010727">
        <property type="entry name" value="DUF1302"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06980">
        <property type="entry name" value="DUF1302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767300" evidence="1">
        <location>
            <begin position="22"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="606" mass="66066" checksum="49BB5FD11C7ECED7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL6</accession>
    <name>B1KFL6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326521.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88191">
        <property type="protein sequence ID" value="ACA88191"/>
        <property type="gene ID" value="Swoo_3934"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3934"/>
    <dbReference type="eggNOG" id="ENOG50338WA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147383_0_0_6"/>
    <dbReference type="OMA" id="QYDCELK"/>
    <dbReference type="OrthoDB" id="1635031at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022253">
        <property type="entry name" value="Ribosome_recyc_fac_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12614">
        <property type="entry name" value="RRF_GI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14492" checksum="09B170E83E66FFC7" modified="2008-04-29" version="1">MKPNITISLPSLIHRIGREAVKQAQAIANQFDCDLKRVRRSRNWEVIGEAIKIQSFSTELKNQGDGRFNFLIKKVDTGLLSHSDKLEPLEVKLARLIAANSNITLAELIHITDCTLAEARTARLNSDAW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN0</accession>
    <name>MAO1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent malic enzyme</fullName>
            <shortName evidence="1">NAD-ME</shortName>
            <ecNumber evidence="1">1.1.1.38</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">maeA</name>
        <name type="ordered locus">Swoo_0902</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-malate + NAD(+) = CO2 + NADH + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:12653"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.38"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + oxaloacetate = CO2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:15641"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="1.1.1.38"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.38" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323543.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KFN0"/>
    <dbReference type="SMR" id="B1KFN0"/>
    <dbReference type="STRING" id="392500.Swoo_0902"/>
    <dbReference type="EnsemblBacteria" id="ACA85196">
        <property type="protein sequence ID" value="ACA85196"/>
        <property type="gene ID" value="Swoo_0902"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0902"/>
    <dbReference type="eggNOG" id="COG0281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011405_5_2_6"/>
    <dbReference type="OMA" id="QMWDPVY"/>
    <dbReference type="OrthoDB" id="654531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01619">
        <property type="entry name" value="NAD_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023667">
        <property type="entry name" value="NAD_malic_enz_proteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000186012" description="NAD-dependent malic enzyme">
        <location>
            <begin position="1"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="1">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01619"/>
        </source>
    </evidence>
    <sequence length="562" mass="62455" checksum="8810CCD6F8A93D5D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ3</accession>
    <name>B1KFQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0926"/>
    <dbReference type="EnsemblBacteria" id="ACA85219">
        <property type="protein sequence ID" value="ACA85219"/>
        <property type="gene ID" value="Swoo_0926"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0926"/>
    <dbReference type="eggNOG" id="ENOG5032CT6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2345106_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11325" checksum="E3A72C20EF00901B" modified="2008-04-29" version="1">MLFYGFSAYYAAYTNQYKDLIAQREFSGPEARSLIAPALMTFTTSMWFATSEEHSCSTVKLVNTASEPLKLACKECFWLPTSALNELIREQPLCHPFALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS5</accession>
    <name>B1KFS5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323588.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0948"/>
    <dbReference type="EnsemblBacteria" id="ACA85241">
        <property type="protein sequence ID" value="ACA85241"/>
        <property type="gene ID" value="Swoo_0948"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0948"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147397_0_0_6"/>
    <dbReference type="OMA" id="FWYDQDE"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="49"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="12159" checksum="27DDF8217FC7B9CA" modified="2008-04-29" version="1">MNKQNLFASLPADLTHEVFEQVGGSDTVLIERIVSKAHVTPKGQWYDQDRNEWVMVLKGEAKLQFEDVEPIHLKVGDYIDIPAHCKHRVSWTSEETETLWLAIHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS8</accession>
    <name>B1KFS8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323591.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85244">
        <property type="protein sequence ID" value="ACA85244"/>
        <property type="gene ID" value="Swoo_0951"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0951"/>
    <dbReference type="HOGENOM" id="CLU_2071529_0_0_6"/>
    <dbReference type="OrthoDB" id="1942196at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764413" evidence="2">
        <location>
            <begin position="24"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="12886" checksum="52F7DA19BD9B2EE8" modified="2008-04-29" version="1" precursor="true">MNRKMIAFSGFAIGFLLSTTASATSFSEQDIMLYENAAGRGKLQQIKDFIAQGMPVDAKREYSMSGATPLMLSLKFCKPEIVSFLLKQGASLTIKDEDGETATDYAKKACDEVKSLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG53</accession>
    <name>B1KG53_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA translocase FtsK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2483</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2483"/>
    <dbReference type="EnsemblBacteria" id="ACA86760">
        <property type="protein sequence ID" value="ACA86760"/>
        <property type="gene ID" value="Swoo_2483"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2483"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001981_9_7_6"/>
    <dbReference type="OMA" id="SWLTIVD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025199">
        <property type="entry name" value="FtsK_4TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13491">
        <property type="entry name" value="FtsK_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="14" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="13">
        <location>
            <begin position="489"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="230"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="828"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="246"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="506"/>
            <end position="513"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="850" mass="93893" checksum="1DBE18045609082D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGA3</accession>
    <name>B1KGA3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326570.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3983"/>
    <dbReference type="EnsemblBacteria" id="ACA88240">
        <property type="protein sequence ID" value="ACA88240"/>
        <property type="gene ID" value="Swoo_3983"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3983"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102556_0_0_6"/>
    <dbReference type="OMA" id="LPAHANW"/>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027016">
        <property type="entry name" value="UCP029811"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029811">
        <property type="entry name" value="UCP029811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764847" evidence="1">
        <location>
            <begin position="23"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="24"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="198" mass="21750" checksum="0FFAE3479192528C" modified="2008-04-29" version="1" precursor="true">MKTTFATLLLSIALLGSTQASAQWTLDSNSAALNFLSTKVLINKQSITEVSGFNTLSGTVSDDGEFMLMVQLESVNTQVPIRDQRLRDWVFQVEKYSRVEISGQISKLELKDLAIGKPKGITQALILKTHGKVLTLKAELQLVKSADGALHVSTLTPILLDIKQLDMNLGVEKLIEVMGLASINQQIPITFYGTFTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGF3</accession>
    <name>B1KGF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4034"/>
    <dbReference type="EnsemblBacteria" id="ACA88290">
        <property type="protein sequence ID" value="ACA88290"/>
        <property type="gene ID" value="Swoo_4034"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4034"/>
    <dbReference type="eggNOG" id="COG3803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065010_2_0_6"/>
    <dbReference type="OMA" id="YMPYMHS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="192" mass="22195" checksum="BFA03CE854DC3619" modified="2008-04-29" version="1">MSSKEHVSLQAENITPDTIINFWFKEIDPKCHWVKDTDFDQQLRSCFGPLLEQAKAGELYHWRATPQGRLAEIIVLDQFSRNIYRDTPQAFEADPMALVLAQEAVAFKVDQEINPTYVPFLFMPYMHSESAKIHEIAMVLFKREAAQVSLSFEERHKAIIDRFGRYPHRNEILGRSSTADELEFLSEPGSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL2</accession>
    <name>B1KGL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323686.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1047"/>
    <dbReference type="EnsemblBacteria" id="ACA85340">
        <property type="protein sequence ID" value="ACA85340"/>
        <property type="gene ID" value="Swoo_1047"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1047"/>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_1_0_6"/>
    <dbReference type="OMA" id="DNQDTAH"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23223" checksum="F1AD60D8C19B3479" modified="2008-04-29" version="1">MNLLIVSGSQRTQSQSAKVASYLAQITTEFSQSSHIELCTHELPFWDGEAESKLDKGSPWPMISQKVKRADALILITPEWGGMASPLLKNFLLMCDNQDTAHKPALLVSVVSGISGAYPIAELRMNALKNNKLVALPDHLIIRNVEEVLNGKPEANGNQVANSATRESALEGRIQYSLHMLYQYAEALSGIRARHSAQPYPKQQEYIYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGP3</accession>
    <name>B1KGP3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Permease YjgP/YjgQ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1078</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LptF/LptG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323717.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1078"/>
    <dbReference type="EnsemblBacteria" id="ACA85371">
        <property type="protein sequence ID" value="ACA85371"/>
        <property type="gene ID" value="Swoo_1078"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1078"/>
    <dbReference type="eggNOG" id="COG0795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028799_1_1_6"/>
    <dbReference type="OMA" id="WFTSKLA"/>
    <dbReference type="OrthoDB" id="1558251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030923">
        <property type="entry name" value="LptG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04408">
        <property type="entry name" value="LptG_lptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="352" mass="38946" checksum="6803811139C33976" modified="2008-04-29" version="1">MRILDFYIARTLVSTSALCLLILTGLSGIIKWVDQLRVVGRGSYTMLDAGIYVLFLIPRDIEMFFPMAVLLGALIGMGMLASNSELVVMQSAGLSRLQITLSAMKTAVPLMLIIMALGEWGAPAAEQKAYELQATKISGGSLIKSSRGIWAKDGDLFVNIGEVEDINNLRNITLYKFNSDLALTRTIHAERGVFSKDHWRLLDVRQTDLTDERVTLTDLTLYRWESTLTPDKLSVVSVKPESLSIQGLIGYLDYLEVNNQDASRYELALWRKFMQPVTVAVMMLVALSFVFGPLRTVTMGARVLLGVIAGFSFYISSEIFGPLTLVYGLPAYIGAMMPALIFGVGAIYFIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGZ0</accession>
    <name>B1KGZ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326631.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4046"/>
    <dbReference type="EnsemblBacteria" id="ACA88302">
        <property type="protein sequence ID" value="ACA88302"/>
        <property type="gene ID" value="Swoo_4046"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4046"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_1_6"/>
    <dbReference type="OMA" id="EYKGAWD"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="33632" checksum="25E8423BC489C145" modified="2008-04-29" version="1">MQANGELDNYIRVMDRVCDYIYANLDEELTVDHLSDFAGFSKFHFHRQFSDYLGIGIAKYIQLLRLKRASYRLYFDREAKIIDIALDAKFDYPESFARAFKKAFDQSPTEFRSQPKWLEWNEKYHFGVKKMGKDQKVELVNFAETRIAVFEHRGAPELVNESAAKFIAWRKQTGLSPVSKSQTFGMIYEDPKSVPAEDFRFDICGSVLHEVPDNSHGVLNKVIPQGRCAVIRHHGSHDALDAKVHYLYGQWLPKSGESLRDFPCFFHYQNFFPEVAEHELITDIYLPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH51</accession>
    <name>B1KH51_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4107</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326692.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4107"/>
    <dbReference type="EnsemblBacteria" id="ACA88363">
        <property type="protein sequence ID" value="ACA88363"/>
        <property type="gene ID" value="Swoo_4107"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4107"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_0_1_6"/>
    <dbReference type="OMA" id="PQSFHWT"/>
    <dbReference type="OrthoDB" id="856767at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="711"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="755"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="803"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="488"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="742"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="840" mass="92686" checksum="FE0817E952670CEF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH78</accession>
    <name>B1KH78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323732.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85386">
        <property type="protein sequence ID" value="ACA85386"/>
        <property type="gene ID" value="Swoo_1093"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1093"/>
    <dbReference type="eggNOG" id="ENOG50334IN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1261029_0_0_6"/>
    <dbReference type="OMA" id="IKHHKAY"/>
    <dbReference type="OrthoDB" id="1449874at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021316">
        <property type="entry name" value="DUF2913"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11140">
        <property type="entry name" value="DUF2913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23456" checksum="8B4CF7598578AD23" modified="2008-04-29" version="1">MTEQTYNQALLELVQAGLSALKQRAAGSNAINTATAESHFLCSWMVQALKERRFAKLVAQDLTRWIREARSKGAGAQLPSLFKRIDNQYSAVLNKTQLGDALQAMLTELEESDWLVILDAEVDTKLKLDSDGRCSLIISVEQYQQRIKEQKIVKPITLYVRADEQLLAQAAAKHGLLISQGDKKASLIKHHKAYQVYPGNRQPALALLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF0</accession>
    <name>B1KHF0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Major outer membrane lipoprotein Lpp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lpp</name>
        <name evidence="8" type="ordered locus">Swoo_1165</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell outer membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <orientation evidence="3">Periplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Cell wall</location>
            <topology evidence="3">Peptidoglycan-anchor</topology>
        </subcellularLocation>
        <text evidence="3">Attached via its lipidated N-terminus to the inner leaflet of the outer membrane. Attached to the peptidoglycan network (PGN) via its C-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Lpp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323804.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1165"/>
    <dbReference type="EnsemblBacteria" id="ACA85458">
        <property type="protein sequence ID" value="ACA85458"/>
        <property type="gene ID" value="Swoo_1165"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1165"/>
    <dbReference type="eggNOG" id="COG4238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166934_1_1_6"/>
    <dbReference type="OMA" id="ANDRIDN"/>
    <dbReference type="OrthoDB" id="1991143at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043580">
        <property type="term" value="P:periplasmic space organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00843">
        <property type="entry name" value="Lpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006817">
        <property type="entry name" value="Lipoprotein_leucine-zipper_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016367">
        <property type="entry name" value="MOM_Lpp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38763">
        <property type="entry name" value="PTHR38763"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04728">
        <property type="entry name" value="LPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002855">
        <property type="entry name" value="Murein-lipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3 5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3 5" id="KW-0564">Palmitate</keyword>
    <keyword evidence="3 4" id="KW-0572">Peptidoglycan-anchor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764479" description="Major outer membrane lipoprotein Lpp" evidence="6">
        <location>
            <begin position="22"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" evidence="3">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="LPP" evidence="7">
        <location>
            <begin position="36"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="30"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-murein peptidoglycan lysine" evidence="3 4">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="N-palmitoyl cysteine" evidence="3 5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="S-diacylglycerol cysteine" evidence="3 5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR002855-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002855-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="9026" checksum="4F9A4D8A7B1873F0" modified="2008-04-29" version="1" precursor="true">MNKKVLMIAGVAMTALLGGCANTTALEESVANLGNKVDQLSSEVSALKSEQGALSADVKDAKAAAMDAQAEAQRANARIDNVASSYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHN4</accession>
    <name>B1KHN4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RecBCD enzyme subunit RecB</fullName>
            <ecNumber evidence="8">3.1.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Exonuclease V subunit RecB</fullName>
            <shortName evidence="8">ExoV subunit RecB</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Helicase/nuclease RecBCD subunit RecB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">recB</name>
        <name evidence="12" type="ordered locus">Swoo_2642</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.</text>
            <dbReference type="EC" id="3.1.11.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.5" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325259.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2642"/>
    <dbReference type="EnsemblBacteria" id="ACA86919">
        <property type="protein sequence ID" value="ACA86919"/>
        <property type="gene ID" value="Swoo_2642"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2642"/>
    <dbReference type="eggNOG" id="COG1074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001114_6_0_6"/>
    <dbReference type="OMA" id="KQSIYRW"/>
    <dbReference type="OrthoDB" id="137860at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01485">
        <property type="entry name" value="RecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004586">
        <property type="entry name" value="RecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF23">
        <property type="entry name" value="PTHR11070:SF23"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00609">
        <property type="entry name" value="recB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="10">
        <location>
            <begin position="9"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="11">
        <location>
            <begin position="491"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="DNA-binding and helicase activity, interacts with RecC" evidence="8">
        <location>
            <begin position="1"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Nuclease activity, interacts with RecD and RecA" evidence="8">
        <location>
            <begin position="925"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="active site" description="For nuclease activity" evidence="8">
        <location>
            <position position="1104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="982"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="1091"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="1104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1229" mass="138900" checksum="F1B78C1140B8A6A7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP1</accession>
    <name>B1KHP1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325266.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2649"/>
    <dbReference type="EnsemblBacteria" id="ACA86926">
        <property type="protein sequence ID" value="ACA86926"/>
        <property type="gene ID" value="Swoo_2649"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2649"/>
    <dbReference type="HOGENOM" id="CLU_642341_0_0_6"/>
    <dbReference type="OrthoDB" id="946992at1224"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="427" mass="49374" checksum="ECF54ECE4DA40C7E" modified="2008-04-29" version="1">MKEENIPNWWKQAIAIEYLPCRDYLKGDRLSQFDFSLVTKEQLEEAINKYKIVSYGTVIHNVDPRTFQQKRMLGLLGGVTKPIVEGDSAAIIPNGIVSKIHFPNLVNPIDVCDPLETFNSHIQVLDEGILYQWEIARFEGVKDRHYGRWVSDYVDLSAFDEDHDEFQELCFLKQQTKNNPEEYVERARCYIEKIQSLRLGVFKQLLEIHNEFKMSDRTSKKKVVDYPPPLLSHFETMKIEDGEISTKASMAPIFYRSALKHRLQAKKLQSPNEKYSIHILDEIHQERAEAIIMAAACLEAVVNEVGDTKHKEIWSGVEKLSLNEKYKTVFYLSGKPDDFDISKSPFQFLNKLISVRNEMIHFKPGYKRVKVLNGKSTSRLDTLLDIELIDKLPMILCDSINALYKVADSPLPEWLSDKPGWKLSEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ9</accession>
    <name>B1KHQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326716.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4131"/>
    <dbReference type="EnsemblBacteria" id="ACA88387">
        <property type="protein sequence ID" value="ACA88387"/>
        <property type="gene ID" value="Swoo_4131"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4131"/>
    <dbReference type="eggNOG" id="COG2039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048887_0_0_6"/>
    <dbReference type="OMA" id="YWARLGM"/>
    <dbReference type="OrthoDB" id="1753364at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="SSF53182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767357" evidence="1">
        <location>
            <begin position="25"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="42369" checksum="62C7A45F19BF89E5" modified="2008-04-29" version="1" precursor="true">MNRVSTALLFSGLLSLLPNANANAQIDLDIEESRIESATATLPEVTARYQGIIDSLSSQYRQDTDELSVTKMAARQGERLWQQAVRDVQSGNIDDRPLYWSRLTMLKELKTAKSGFNIAPWQREILLNAVEKSSRGFSNIKFDDDAQIKILLSGFDPFFLDRNIGQSNPSGVTALALDGYLFTVAGKKAQIETVMIPVRFADFDEGLIESLLTPVYRENSVDMIFTVSMGRDDFDLERFPGRNRSAAAPDNLNVLTGANKQNPLAPLFEGKNLNGPEFVEFSLPVKAMQSAQGKWKVNDNHSVTTLAKGAFDASSLAELESATSVEGSGGGYLSNEISYRAVLLGQQLNSQIPVGHIHTPRVSGYDAETEAEILAQVKAMVIAAAASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHW2</accession>
    <name>B1KHW2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326769.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4184"/>
    <dbReference type="EnsemblBacteria" id="ACA88440">
        <property type="protein sequence ID" value="ACA88440"/>
        <property type="gene ID" value="Swoo_4184"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4184"/>
    <dbReference type="eggNOG" id="ENOG5032Z0A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147302_0_0_6"/>
    <dbReference type="OMA" id="WAQRNRQ"/>
    <dbReference type="OrthoDB" id="1757893at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021813">
        <property type="entry name" value="DUF3392"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11872">
        <property type="entry name" value="DUF3392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="12483" checksum="FCDA2372A8C3B66C" modified="2008-04-29" version="1">MEQIISIFHQVGSLLYPWLNEVATAIIACFLVAFGADINRFLRRKLLGRSFILRTFTFVLVNAFGYGMLIVTVSPLLARSMAKLPAPWLLWSVILVFLLIGSWAQKNRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI24</accession>
    <name>B1KI24_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1209</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1209"/>
    <dbReference type="EnsemblBacteria" id="ACA85502">
        <property type="protein sequence ID" value="ACA85502"/>
        <property type="gene ID" value="Swoo_1209"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1209"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020533_0_0_6"/>
    <dbReference type="OMA" id="ADDGHTF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="714" mass="81499" checksum="7271968550732FFC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-01-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI32</accession>
    <name>MTNN_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase</fullName>
            <shortName evidence="1">MTA/SAH nucleosidase</shortName>
            <shortName evidence="1">MTAN</shortName>
            <ecNumber evidence="1">3.2.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5'-deoxyadenosine nucleosidase</fullName>
            <shortName evidence="1">DOA nucleosidase</shortName>
            <shortName evidence="1">dAdo nucleosidase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">5'-methylthioadenosine nucleosidase</fullName>
            <shortName evidence="1">MTA nucleosidase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">S-adenosylhomocysteine nucleosidase</fullName>
            <shortName evidence="1">AdoHcy nucleosidase</shortName>
            <shortName evidence="1">SAH nucleosidase</shortName>
            <shortName evidence="1">SRH nucleosidase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mtnN</name>
        <name type="ordered locus">Swoo_1217</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + S-adenosyl-L-homocysteine = adenine + S-(5-deoxy-D-ribos-5-yl)-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:17805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58195"/>
            <dbReference type="EC" id="3.2.2.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + S-methyl-5'-thioadenosine = 5-(methylsulfanyl)-D-ribose + adenine</text>
            <dbReference type="Rhea" id="RHEA:13617"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:78440"/>
            <dbReference type="EC" id="3.2.2.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5'-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine</text>
            <dbReference type="Rhea" id="RHEA:29859"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:149540"/>
            <dbReference type="EC" id="3.2.2.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:29860"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route): step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323856.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI32"/>
    <dbReference type="SMR" id="B1KI32"/>
    <dbReference type="STRING" id="392500.Swoo_1217"/>
    <dbReference type="EnsemblBacteria" id="ACA85510">
        <property type="protein sequence ID" value="ACA85510"/>
        <property type="gene ID" value="Swoo_1217"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1217"/>
    <dbReference type="eggNOG" id="COG0775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031248_2_2_6"/>
    <dbReference type="OMA" id="DQFVHSK"/>
    <dbReference type="OrthoDB" id="1860206at2"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00871"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008782">
        <property type="term" value="F:adenosylhomocysteine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008930">
        <property type="term" value="F:methylthioadenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01684">
        <property type="entry name" value="Salvage_MtnN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010049">
        <property type="entry name" value="MTA_SAH_Nsdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01704">
        <property type="entry name" value="MTA/SAH-Nsdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0486">Methionine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000359355" description="5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="174"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01684"/>
        </source>
    </evidence>
    <sequence length="230" mass="24217" checksum="D21D514AC4105136" modified="2008-04-29" version="1">MKVGIIGAMEPEVAHLIASMDNAESQTIAGIEFVAGTLDGKEVIVTRSGIGKVAASIATTLLIEKYTPDAVINTGSAGGFVDTLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFMPDEKLKAAANKAVASLGEVKAIEGLICTGDSFICDPVRTKTMLEHFPTMAACEMEGAAIAQVCHQFAVPFVVIRSLSDNANNDSPVDFDSYIVKAGHHSALMVMSLLKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI43</accession>
    <name>B1KI43_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoenolpyruvate--protein phosphotransferase</fullName>
            <ecNumber evidence="5">2.7.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1228</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323867.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1228"/>
    <dbReference type="EnsemblBacteria" id="ACA85521">
        <property type="protein sequence ID" value="ACA85521"/>
        <property type="gene ID" value="Swoo_1228"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1228"/>
    <dbReference type="eggNOG" id="COG3605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_7_1_6"/>
    <dbReference type="OMA" id="MFPMISE"/>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GAF" evidence="11">
        <location>
            <begin position="17"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="744" mass="82412" checksum="B9B4F2603D6BD877" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE4</accession>
    <name>B1KIE4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2719</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325332.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2719"/>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86995">
        <property type="protein sequence ID" value="ACA86995"/>
        <property type="gene ID" value="Swoo_2719"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2719"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_13_0_6"/>
    <dbReference type="OMA" id="WAGNPSH"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032798">
        <property type="entry name" value="CBM_5_12_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009470">
        <property type="entry name" value="Chi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14600">
        <property type="entry name" value="CBM_5_12_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06483">
        <property type="entry name" value="ChiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767086" evidence="3">
        <location>
            <begin position="34"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="4">
        <location>
            <begin position="403"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1129" mass="121318" checksum="01D72E554BFFB63F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIF3</accession>
    <name>B1KIF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325341.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2728"/>
    <dbReference type="EnsemblBacteria" id="ACA87004">
        <property type="protein sequence ID" value="ACA87004"/>
        <property type="gene ID" value="Swoo_2728"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2728"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038666_0_0_6"/>
    <dbReference type="OMA" id="LEGDMNR"/>
    <dbReference type="OrthoDB" id="837523at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045748">
        <property type="entry name" value="DcaP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19577">
        <property type="entry name" value="DcaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764523" evidence="1">
        <location>
            <begin position="23"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="379" mass="41069" checksum="ED8AD34D81CAEE9B" modified="2008-04-29" version="1" precursor="true">MKQAKLSLIAMATMLAASSAAAGDTEFKFGGYVKADVMFSDYSNGAPDSGSLSRQFYVPGTIYGVEGNGEQVVDFQARESRFNFKTSTDLGGHKLSGFIELDFMTHADGNERVSNSYSPRIRHAIVSFDNWTVGQTWTTFQNPGALPENLDFVGAAEGTPFVRQSMVRYTNGGFQFAVENPETTLTPNGGGGRITSGSGMVPDFVARYNFKTEGGAKFTVAGLARQLNIEKDGLDAQTLGYGVSFTGVVPVGDDDFKVSATVGDGMGRYMALNYANAGVIDNNGDIETISSYGGFASYRHWWNDKWRSSFTLSGFKADNTESLTGLGVNKESYSGYVNLLYSPIKPMTVGVEYMYAENTKESGDKGELNRVIFSVKYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM6</accession>
    <name>B1KIM6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326849.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4266"/>
    <dbReference type="EnsemblBacteria" id="ACA88522">
        <property type="protein sequence ID" value="ACA88522"/>
        <property type="gene ID" value="Swoo_4266"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4266"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092618_0_1_6"/>
    <dbReference type="OMA" id="GCMETLW"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="171" mass="19394" checksum="159E28567175A2CF" modified="2008-04-29" version="1">MKKIAVFGKPGSGKSTMSKALALATGIPLYQLDSIVYEPSGKLVPREMFDKTHEKILSGETWIIDGFGPIDSFHQRLDAADTLVYIDLPYLMSYWFVTKRFLKGLVVKPEGWPDGSSVLKGTLESYKVLRLCPKFWNDDFVSKLQERSNTKEVIVIRTVSELNEFARQNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM7</accession>
    <name>B1KIM7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4267</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4267"/>
    <dbReference type="EnsemblBacteria" id="ACA88523">
        <property type="protein sequence ID" value="ACA88523"/>
        <property type="gene ID" value="Swoo_4267"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4267"/>
    <dbReference type="eggNOG" id="COG2015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014655_1_0_6"/>
    <dbReference type="OMA" id="YFGSHHW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="5">
        <location>
            <begin position="168"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="696" mass="76128" checksum="091C462ED3D0A521" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP9</accession>
    <name>B1KIP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326872.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4290"/>
    <dbReference type="EnsemblBacteria" id="ACA88545">
        <property type="protein sequence ID" value="ACA88545"/>
        <property type="gene ID" value="Swoo_4290"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4290"/>
    <dbReference type="eggNOG" id="ENOG502Z8IE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012035_1_0_6"/>
    <dbReference type="OMA" id="LPWQSDF"/>
    <dbReference type="OrthoDB" id="1584770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033736">
        <property type="term" value="F:L-lysine 6-oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031640">
        <property type="term" value="P:killing of cells of another organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900191">
        <property type="term" value="P:negative regulation of single-species biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14732">
        <property type="entry name" value="LodA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033797">
        <property type="entry name" value="LodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041173">
        <property type="entry name" value="LodA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041168">
        <property type="entry name" value="LodA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18417">
        <property type="entry name" value="LodA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17990">
        <property type="entry name" value="LodA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LodA_N" evidence="2">
        <location>
            <begin position="9"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="LodA_C" evidence="3">
        <location>
            <begin position="431"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="700" mass="77265" checksum="AF81B1CFE79B830C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV5</accession>
    <name>B1KIV5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">N-acetyl-beta-glucosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1311</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323949.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1311"/>
    <dbReference type="CAZy" id="GH20">
        <property type="family name" value="Glycoside Hydrolase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85603">
        <property type="protein sequence ID" value="ACA85603"/>
        <property type="gene ID" value="Swoo_1311"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1311"/>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007082_4_1_6"/>
    <dbReference type="OMA" id="DVIPRPY"/>
    <dbReference type="OrthoDB" id="727559at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02847">
        <property type="entry name" value="E_set_Chitobiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004866">
        <property type="entry name" value="CHB/HEX_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004867">
        <property type="entry name" value="CHB_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03173">
        <property type="entry name" value="CHB_HEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03174">
        <property type="entry name" value="CHB_HEX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SMART" id="SM01081">
        <property type="entry name" value="CHB_HEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766673" description="Beta-N-acetylhexosaminidase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="domain" description="CHB_HEX" evidence="8">
        <location>
            <begin position="52"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="888" mass="98451" checksum="98FEB87A8B1BB634" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV9</accession>
    <name>B1KIV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glucose/galactose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_1315</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Intake of glucose and galactose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1315"/>
    <dbReference type="EnsemblBacteria" id="ACA85607">
        <property type="protein sequence ID" value="ACA85607"/>
        <property type="gene ID" value="Swoo_1315"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1315"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028452_2_2_6"/>
    <dbReference type="OMA" id="NSLMWPA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005354">
        <property type="term" value="F:galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005355">
        <property type="term" value="F:glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005964">
        <property type="entry name" value="Glc/Gal_transptr_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01272">
        <property type="entry name" value="gluP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="410"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="13">
        <location>
            <begin position="16"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="435" mass="46455" checksum="D1803BA9A234BCAA" modified="2008-04-29" version="1">MEMTLNSDNKRSSIIPMTIVAVLFFVLGFATWLNGSLMPYLKQILQLTPLQASLILFSFYIAVTFTALPSAWLIRKVGYKNGMALGMGVMMLAGLLFIPAAKTQIFALFLFAQLVMGAGQTLLQTAVNPYVVRIGPEESAAARVSVMGILNKGAGVIAPLVFSALILNSFKDRVGTELTSAQIDEMANGLVLPYLGMALFIGLLALVVKKSPLPELTDEDEGEQTNNKGQIKEALSHPNLAFGVVALFFYVAVEVIAGDTIGTFALSLGIESYGVMTSYTMICMVLGYTLGILTIPRFISQPKALMISAILGLILTIGIVFGDNESYAIANTLLVPFGGAQLPDTLLMIAFLGLANAIVWPAVWPLALSGMGKLTSTGSALLVMGIAGGAFGPLFWGLTSSVSSLGQQGGYMVMLPCYLFILFYAVKGYKMKSWK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJC0</accession>
    <name>FTHS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="1">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="1">FHS</shortName>
            <shortName evidence="1">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fhs</name>
        <name type="ordered locus">Swoo_4339</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326918.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJC0"/>
    <dbReference type="SMR" id="B1KJC0"/>
    <dbReference type="STRING" id="392500.Swoo_4339"/>
    <dbReference type="EnsemblBacteria" id="ACA88592">
        <property type="protein sequence ID" value="ACA88592"/>
        <property type="gene ID" value="Swoo_4339"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4339"/>
    <dbReference type="eggNOG" id="COG2759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003601_3_3_6"/>
    <dbReference type="OMA" id="CGEIMTM"/>
    <dbReference type="OrthoDB" id="177859at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0554">One-carbon metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000196824" description="Formate--tetrahydrofolate ligase">
        <location>
            <begin position="1"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <sequence length="570" mass="60642" checksum="8596D91447E9335C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJC7</accession>
    <name>B1KJC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326925.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4346"/>
    <dbReference type="EnsemblBacteria" id="ACA88599">
        <property type="protein sequence ID" value="ACA88599"/>
        <property type="gene ID" value="Swoo_4346"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4346"/>
    <dbReference type="eggNOG" id="ENOG50331S4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100616_1_0_6"/>
    <dbReference type="OMA" id="PRMTFSY"/>
    <dbReference type="OrthoDB" id="1666830at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021557">
        <property type="entry name" value="DUF3016"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11454">
        <property type="entry name" value="DUF3016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767122" evidence="1">
        <location>
            <begin position="20"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19477" checksum="65C9C3C8EE28AF19" modified="2008-04-29" version="1" precursor="true">MKLTYLLLAGAMASGAVVAADEAVENPVTEKGVVKIEWKDPKSFRDVKAASDIQSRYEMRTFETLTKNLNKEASKILKPNQKLEMQVTDLDLAGDVRPTFGATTSDIRVIKDIYPPRITFTYTVTQDGKTVMAGDEKLTDLGFMHSIGRMNEKPTRYESKLLADWMKKTVAPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG2</accession>
    <name>B1KJG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Two component transcriptional regulator, LytTR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4382</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326960.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4382"/>
    <dbReference type="EnsemblBacteria" id="ACA88634">
        <property type="protein sequence ID" value="ACA88634"/>
        <property type="gene ID" value="Swoo_4382"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4382"/>
    <dbReference type="eggNOG" id="COG3279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_14_1_6"/>
    <dbReference type="OMA" id="HTANQKF"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="168"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="273" mass="31316" checksum="A045FDAB369E7C74" modified="2008-04-29" version="1">MIKLRTLIIDDEPLALKLLGSKLKNIPEIEIVAQCNNGREAIAATIEFEPDLIFLDIQMPGIDGFGVIKKLQTEILPLVIFTTAFEQYALDAFDVHAVDYILKPIDDEHIQRAVSRAIQRFETGETRENKPKIIGAINEINLRERRADAHENNQTDKPTSLDNIERKIVIKDRDNITILKQSEIEWIDAAGDYVCIHTDAETHIKRSTLKNLLQDLDPSIFKRVHRSTIVNLNYIQKVIPHTKGEFFLKLGEYDQVKVSRNYRDVIKSFLSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJK7</accession>
    <name>B1KJK7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylglycerophosphatase A</fullName>
            <ecNumber evidence="1">3.1.3.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphatidylglycerolphosphate phosphatase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1388</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:33751"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="EC" id="3.1.3.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.27" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324026.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1388"/>
    <dbReference type="EnsemblBacteria" id="ACA85680">
        <property type="protein sequence ID" value="ACA85680"/>
        <property type="gene ID" value="Swoo_1388"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1388"/>
    <dbReference type="eggNOG" id="COG1267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103734_0_1_6"/>
    <dbReference type="OMA" id="VWDEIAG"/>
    <dbReference type="OrthoDB" id="1969080at2"/>
    <dbReference type="UniPathway" id="UPA00084">
        <property type="reaction ID" value="UER00504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006655">
        <property type="term" value="P:phosphatidylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06971">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026037">
        <property type="entry name" value="PgpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036681">
        <property type="entry name" value="PgpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007686">
        <property type="entry name" value="YutG/PgpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36305">
        <property type="entry name" value="PTHR36305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04608">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006162">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101307">
        <property type="entry name" value="SSF101307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0595">Phospholipid degradation</keyword>
    <keyword evidence="1" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="PgpA" evidence="3">
        <location>
            <begin position="20"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="17859" checksum="3AE3482A0C0A78D4" modified="2008-04-29" version="1">MNFLSKDEALSRLSLTNPIHFLALGFGSGMMAKAPGTFGTLAAIPLYLLMAPLSIQWYLGLTLLSVIAGFYICDKAAKDMGVHDHGAIVWDEVAGLLITMIAAPAGWLWLVIGFALFRFFDIIKPWPIRWLDAKVKGGFGIMIDDVLAGIFSLACLQGLAYFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJP0</accession>
    <name>B1KJP0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase</fullName>
            <ecNumber evidence="8">4.2.1.59</ecNumber>
            <ecNumber evidence="7">5.3.3.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Beta-hydroxydecanoyl thioester dehydrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Trans-2-decenoyl-[acyl-carrier-protein] isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Swoo_1421</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the thioester dehydratase family. FabA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="8"/>
    <dbReference type="EC" id="5.3.3.14" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324059.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1421"/>
    <dbReference type="EnsemblBacteria" id="ACA85713">
        <property type="protein sequence ID" value="ACA85713"/>
        <property type="gene ID" value="Swoo_1421"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1421"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_30_0_6"/>
    <dbReference type="OMA" id="CIDVAQN"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034017">
        <property type="term" value="F:trans-2-decenoyl-acyl-carrier-protein isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01287">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010083">
        <property type="entry name" value="FabA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="17">
        <location>
            <begin position="14"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00017810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACA85713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1951" mass="210695" checksum="D0E4058CA3FCD0B2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ1</accession>
    <name>B1KJZ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325514.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2905"/>
    <dbReference type="EnsemblBacteria" id="ACA87178">
        <property type="protein sequence ID" value="ACA87178"/>
        <property type="gene ID" value="Swoo_2905"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2905"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_6"/>
    <dbReference type="OMA" id="SPIGHIE"/>
    <dbReference type="OrthoDB" id="1135906at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="26377" checksum="1E4F09FEB3B1D640" modified="2008-04-29" version="1">MLEYQAAKDLLINKTILVTGAGDGIGRAAAISFAKHGATVILLGKTVKKLEAVYDVIEQAGYPKPAIVPLDLKGATEQNYIDMAETIEQQFGHLDGLLHNASMLGVLGPFEHISMDSVKEVMQVNVIAEVMMTKALLPVMKKAPQASLVFTSSSVGRQGKAFWGEYAISKFATEGMMQAIAHEYDGSNVRANSINPGATRTGMRANAYPAENPQSIKAPEEIMATYLYLMGNDSLEVNGQQLNAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK55</accession>
    <name>B1KK55_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aromatic amino acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4434</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in transporting aromatic amino acids across the cytoplasmic membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell inner membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327012.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4434"/>
    <dbReference type="EnsemblBacteria" id="ACA88686">
        <property type="protein sequence ID" value="ACA88686"/>
        <property type="gene ID" value="Swoo_4434"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4434"/>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038102_3_0_6"/>
    <dbReference type="OMA" id="PHIHQVN"/>
    <dbReference type="OrthoDB" id="935253at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013061">
        <property type="entry name" value="Trp/try_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46997">
        <property type="entry name" value="PTHR46997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00837">
        <property type="entry name" value="araaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00594">
        <property type="entry name" value="AROMATIC_AA_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="267"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="400" mass="42685" checksum="9B130956835318E3" modified="2008-04-29" version="1" precursor="true">MNKSKTFGSMLIIAGTTIGAGMLALPLASSGLGFGTASVIMLLIWSLMAYTALLMVEVHQFAPVDATLHTLAYKLLGRKGQLVASFSMMFLFYALCAAYIAGGGEQIHSKLTGWFALDLPMQAGAILFTLLIGTVVAIGTHSVDFINRSLFSLKLVALVVMLFLLLPHVSVNNLVELPVHQGLVLASLPVIFTSFGFHGSIPSIVRYLGKDTKALRWIIVVGSALPLLIYLLWLVASQGVLTQSTLMNSQSLNGFISSLSSLLHDPMIANAVSIFADLALATSFLGVSLGLYDFLSDLLKRSKTATHRVQIAGVTFLPPLGFALFYPQGFITALGYAAFALVVLAIFLPVAMVASQRKQQELEGYRVKGGKAGLIIVTLAGVLIMLVQLLQMVNLLPAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG3</accession>
    <name>B1KKG3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324149.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1515"/>
    <dbReference type="EnsemblBacteria" id="ACA85803">
        <property type="protein sequence ID" value="ACA85803"/>
        <property type="gene ID" value="Swoo_1515"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1515"/>
    <dbReference type="eggNOG" id="COG3528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055418_1_0_6"/>
    <dbReference type="OMA" id="WQYQVEN"/>
    <dbReference type="OrthoDB" id="1111569at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018707">
        <property type="entry name" value="LpxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037107">
        <property type="entry name" value="Put_OMP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09982">
        <property type="entry name" value="DUF2219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="331" mass="37705" checksum="5E16209A2C5A408B" modified="2008-04-29" version="1" precursor="true">MNICHLRSISLFSSLLLCSQVYGGQWHLQLDNDIIFGSDGNYTNGMILGWESAAQDRRSELPTPLQWQRLFLFNQQEGEIAWGAKFNQRMWTPAEIEVATPQPDDRPYAGLLTIESHTAHYGVNLSQKNWLSLGVMGPLSGAQQVQEFVHKFTDSSPPLGWQYQVENQVTIQLAYEVDALMLRRDAFNHALTGKTQWELSGFSHTQAGNFRSENELGVLFRWGNDLEHSFGRLSQHSGHLGNLTSVKGFSNFIFYSRAFVGYRFNDLSLEGSLPYDSHLMLEHLQYGVKSGIIWSHSNGSVSWSFNSYSQEYQNDKQSWHGYGSLTFSWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL8</accession>
    <name>B1KKL8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325571.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2964"/>
    <dbReference type="EnsemblBacteria" id="ACA87235">
        <property type="protein sequence ID" value="ACA87235"/>
        <property type="gene ID" value="Swoo_2964"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2964"/>
    <dbReference type="HOGENOM" id="CLU_179252_0_0_6"/>
    <dbReference type="OrthoDB" id="2058271at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="87" mass="9787" checksum="B37C8E77B9CF14EE" modified="2008-04-29" version="1">MGAGGRRDPSEYTSIICEVFYDASRRKNGVRPVVGQPFPNDMKVECAKAIRALPLGTQIKLSVVETEKEGSRPFLYSSYKWAYDIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKM5</accession>
    <name>B1KKM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2971</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325578.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2971"/>
    <dbReference type="EnsemblBacteria" id="ACA87242">
        <property type="protein sequence ID" value="ACA87242"/>
        <property type="gene ID" value="Swoo_2971"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2971"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_6"/>
    <dbReference type="OMA" id="AFMIRAC"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="226"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="330" mass="36835" checksum="CCB17ABAEAEC3F99" modified="2008-04-29" version="1">MNMANRDLELNGARDLTLEDKPYLDVLSDVLRMIRLYASSYYCAEFSSPWGIDEPQAECGTFHVVIRGSAWLMTEELTSPVFLSTGDIIAFPTGSPHQISEQPGSQLMSGGEVLEKIRSNSSPFSDGQSVVTLLCGYFQYQTDISLPLLRDMPSMLHIKTEEEPELAWLNHLIKTLAYESRSLQPGNAVVVDRLTEVLVIQLLRWHMRHQRNTPGYFQALGDDKLSRALILIHQEPSKAWTVESLGRAVSMSRTSFANRFQSIVGMTPLAYLSQWRMHIAYGLLVEGELSMLSIAEQVGYKSEASFGKAFKKIVGISPGKVAKGETQPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR8</accession>
    <name>B1KKR8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YfcL protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325621.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3014"/>
    <dbReference type="EnsemblBacteria" id="ACA87285">
        <property type="protein sequence ID" value="ACA87285"/>
        <property type="gene ID" value="Swoo_3014"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3014"/>
    <dbReference type="eggNOG" id="ENOG5032D8I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183014_0_0_6"/>
    <dbReference type="OMA" id="GMWENLY"/>
    <dbReference type="OrthoDB" id="2020460at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014987">
        <property type="entry name" value="UPF_YfcL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08891">
        <property type="entry name" value="YfcL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="10007" checksum="45A909E8466EE200" modified="2008-04-29" version="1">MLEQYETTLYEWIEDIVAQGNEDALFASGYLQGHFAVAISQLEIETEQDLSALSQKMDVCMELAKQELGDTDYALVDSAWKQLSDRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKU4</accession>
    <name>B1KKU4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4499</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327076.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4499"/>
    <dbReference type="EnsemblBacteria" id="ACA88750">
        <property type="protein sequence ID" value="ACA88750"/>
        <property type="gene ID" value="Swoo_4499"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4499"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_376370_0_0_6"/>
    <dbReference type="OMA" id="PTTLMEC"/>
    <dbReference type="OrthoDB" id="1123871at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="2"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="711" mass="79737" checksum="CBB3250B4889225B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ7</accession>
    <name>B1KKZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327129.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4553"/>
    <dbReference type="EnsemblBacteria" id="ACA88803">
        <property type="protein sequence ID" value="ACA88803"/>
        <property type="gene ID" value="Swoo_4553"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4553"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_7_2_6"/>
    <dbReference type="OMA" id="RMGTIDM"/>
    <dbReference type="OrthoDB" id="1814691at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="56"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="16954" checksum="925CC8E154C5AB23" modified="2008-04-29" version="1">MTTPIQYEILQRVAEVFDKQVPFHNLLGMDIKRYDLDGVEAVVNMKPELIGNIHQQILHGGVTATVLDVVGGLTAFSGLVASRDDWSIEDLQTRLQTLGTIDLRIDYLRPGRGTIFTGTGTVIRAGNRVSVCRMELHNENGDHIAFGTGTYMVG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL08</accession>
    <name>SLMA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid occlusion factor SlmA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">slmA</name>
        <name type="ordered locus">Swoo_4564</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the nucleoid occlusion factor SlmA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327139.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL08"/>
    <dbReference type="SMR" id="B1KL08"/>
    <dbReference type="STRING" id="392500.Swoo_4564"/>
    <dbReference type="EnsemblBacteria" id="ACA88814">
        <property type="protein sequence ID" value="ACA88814"/>
        <property type="gene ID" value="Swoo_4564"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4564"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_5_0_6"/>
    <dbReference type="OMA" id="IEQTVFG"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010974">
        <property type="term" value="P:negative regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01839">
        <property type="entry name" value="NO_factor_SlmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023769">
        <property type="entry name" value="NO_SlmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000188404" description="Nucleoid occlusion factor SlmA">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="HTH tetR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01839"/>
        </source>
    </evidence>
    <sequence length="197" mass="22619" checksum="7812142396A73549" modified="2008-04-29" version="1">MAASPKINRREHILQCLATMLETNPGQRITTAKLAAEVGVSEAALYRHFPSKARMFEGLIDFIEESLLSRINLIMDEEKDTMKRCQHLLQLLLIFAERNPGISRLLNGDALLGEHDRLRSRIGQIFSKIETHLKQILREKTLREGKGFNLDEAILANLLLAVAEGRISQFVRSEFKQKPTTHFEEQWVFIQQQLLQS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC1</accession>
    <name>GUAA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="1">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">guaA</name>
        <name type="ordered locus">Swoo_1560</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324192.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLC1"/>
    <dbReference type="SMR" id="B1KLC1"/>
    <dbReference type="STRING" id="392500.Swoo_1560"/>
    <dbReference type="MEROPS" id="C26.A07"/>
    <dbReference type="EnsemblBacteria" id="ACA85846">
        <property type="protein sequence ID" value="ACA85846"/>
        <property type="gene ID" value="Swoo_1560"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1560"/>
    <dbReference type="eggNOG" id="COG0518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_0_5_6"/>
    <dbReference type="OMA" id="KRKIIGH"/>
    <dbReference type="OrthoDB" id="504464at2"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword id="KW-0332">GMP biosynthesis</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000120413" description="GMP synthase [glutamine-hydrolyzing]">
        <location>
            <begin position="1"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="GMPS ATP-PPase" evidence="1">
        <location>
            <begin position="208"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="235"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <sequence length="525" mass="58425" checksum="18C61325D05C0BBB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD7</accession>
    <name>B1KLD7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transferase hexapeptide repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324208.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1576"/>
    <dbReference type="EnsemblBacteria" id="ACA85862">
        <property type="protein sequence ID" value="ACA85862"/>
        <property type="gene ID" value="Swoo_1576"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1576"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_7_3_6"/>
    <dbReference type="OMA" id="ICCDHIS"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="19409" checksum="85A7308C047F53E6" modified="2008-04-29" version="1">MFKKLSYWFKVKRIGPDIPLTHLLLHSKRLGAWLCRKKFAKFGHNSAMRPGSYAICCDHISIGNDVVIRPGTMLFGSEHGDKSINITIEDLVLIGSGVHIYTANHEFSDPQKPIFSQGHQAPQAVNVCKGAWIGANAIILPGVTLGQNSVIGAGSVVTKDVPPFCVVAGQPAKIIKQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH3</accession>
    <name>B1KLH3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1612"/>
    <dbReference type="EnsemblBacteria" id="ACA85898">
        <property type="protein sequence ID" value="ACA85898"/>
        <property type="gene ID" value="Swoo_1612"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1612"/>
    <dbReference type="eggNOG" id="ENOG5030C0K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168307_0_0_6"/>
    <dbReference type="OMA" id="MTDVEYL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="108" mass="12589" checksum="43A705AF60F14909" modified="2008-04-29" version="1">MQNFQALEELNQALELLLAKLDKEPAESELADELVSELQVLVGKRQLLLNDLLAAIKLEDKTMWLKQLELTQRFEQQAKVIMRHRQELMHLSSKSKRQINFYKSIGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV1</accession>
    <name>B1KLV1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="11" type="ordered locus">Swoo_4581</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327156.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4581"/>
    <dbReference type="EnsemblBacteria" id="ACA88831">
        <property type="protein sequence ID" value="ACA88831"/>
        <property type="gene ID" value="Swoo_4581"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4581"/>
    <dbReference type="eggNOG" id="COG0194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001715_1_2_6"/>
    <dbReference type="OMA" id="EWAVVHG"/>
    <dbReference type="OrthoDB" id="1502854at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="5"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="22897" checksum="D91978AEEF638699" modified="2008-04-29" version="1">MTARGNLFIVSAPSGAGKSSLISGLLKDKPADKQVSVSHTTRQPRPGEVNGQHYHFVSVEEFKALIAENAFFEWAEVFGNYYGTSRKVIEQTLEQGIDVFLDIDWQGAQQVKKVMPEAIGIFILPPSKAELERRLTGRGQDSAEVIAGRMAQAASEISHYDEYDFIIINDDFDTALGDFIAIIRSQRLTGAGQIHTHNDMLNDLLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM32</accession>
    <name>B1KM32_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Heme exporter protein D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4662</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell inner membrane</location>
            <topology evidence="3 11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the CcmD/CycX/HelD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327236.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4662"/>
    <dbReference type="EnsemblBacteria" id="ACA88912">
        <property type="protein sequence ID" value="ACA88912"/>
        <property type="gene ID" value="Swoo_4662"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4662"/>
    <dbReference type="eggNOG" id="COG3114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180892_0_1_6"/>
    <dbReference type="OMA" id="MFFQSWS"/>
    <dbReference type="OrthoDB" id="2101555at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015886">
        <property type="term" value="P:heme transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007078">
        <property type="entry name" value="Haem_export_protD_CcmD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04995">
        <property type="entry name" value="CcmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03141">
        <property type="entry name" value="cytochro_ccmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="66" mass="7698" checksum="4D6EEF301F07F88E" modified="2008-04-29" version="1" precursor="true">MQFDSLADFFNMGGYAFYVWLAYGVTFFSLGTLVISSLRQKRKVLTEIAKKIQREDRLKANRSNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME1</accession>
    <name>B1KME1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lipopolysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1653</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324285.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1653"/>
    <dbReference type="EnsemblBacteria" id="ACA85939">
        <property type="protein sequence ID" value="ACA85939"/>
        <property type="gene ID" value="Swoo_1653"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1653"/>
    <dbReference type="eggNOG" id="COG3765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074107_0_0_6"/>
    <dbReference type="OMA" id="WLIQDIN"/>
    <dbReference type="OrthoDB" id="1184929at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032807">
        <property type="entry name" value="GNVR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13807">
        <property type="entry name" value="GNVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Wzz" evidence="7">
        <location>
            <begin position="22"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GNVR" evidence="8">
        <location>
            <begin position="276"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="321" mass="35679" checksum="60AC542D6A1E6794" modified="2008-04-29" version="1">MNNQNIPQEFKDARFPQTTSEDEIDLRELFKVIWQGKWLIIAITAVFAIGSVIFALSQPNVYKSEALLAPASEEQSGGLSALAGQFGGLASMAGINLGGGGGVDKTQMAIEVMKSRQFASQFIQNHNILPDLMAAEKWNMGDNTITYDSEIYDASANKWVREVKAPFKPKPSMQEAYKEFSKAISVNSAKDTGMVTISVEHLSPSVAQQWVAWLIQDINKVMKERDVAEANRSSEFLNKQIALTNVADIRSILYKLIEEQAKTIMFAEVRDEYVFKTIDPALVPEEKAKPKRALIFVLGTMLGGMLAVMIVLIRHFVRKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG2</accession>
    <name>B1KMG2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase S74 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324306.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1675"/>
    <dbReference type="EnsemblBacteria" id="ACA85960">
        <property type="protein sequence ID" value="ACA85960"/>
        <property type="gene ID" value="Swoo_1675"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1675"/>
    <dbReference type="eggNOG" id="COG5295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_629888_0_0_6"/>
    <dbReference type="OMA" id="WDVAGNE"/>
    <dbReference type="OrthoDB" id="1284730at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030392">
        <property type="entry name" value="S74_ICA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13884">
        <property type="entry name" value="Peptidase_S74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51688">
        <property type="entry name" value="ICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005661797" description="Peptidase S74 domain-containing protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S74" evidence="3">
        <location>
            <begin position="333"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="406"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="435" mass="47018" checksum="5807845FEF9E2CBA" modified="2008-04-29" version="1" precursor="true">MKNKTNIAFKLLPLTLAITMSMATSVQADQVILDDLIVDGSICTGMDCVNGESFGFDTLRLKENNLRIRFMDTSSTSSFPSRDWQITANDSANGGLNKFSIDDIDGAKTPFTIEAGAGSHSLYVDDASRIGIGTNAPVVQVHVKDGNTPTLRLEQDGSSGFTPQTWDVAGNESNFFIRDATNGSNLVFRIQPSAPANSIFVANDGDVGLGDATPDAALDIESGDLMLTDGQVTIRKTNDPKILFNENDVVTDQWEMGVADVYGNSMTILNKDNPLIGYAMYNTGDIYMNHGVDAASQGNKYAWHLLANGNIEQTGDLWVGGNITAQGTISPGSSRATKNNINLIDGNKILDMLSDLDIFSWSYIRDAGTVTHIGPMAEEFYALFNYGVDNKHISPTDTSGISLAAIKALMDKVESQSSKIEQLENTLVQLQNKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KML4</accession>
    <name>B1KML4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1727</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324358.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86012">
        <property type="protein sequence ID" value="ACA86012"/>
        <property type="gene ID" value="Swoo_1727"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1727"/>
    <dbReference type="eggNOG" id="ENOG5033FW8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182257_0_0_6"/>
    <dbReference type="OMA" id="GWYFDEH"/>
    <dbReference type="OrthoDB" id="1973250at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="75" mass="8449" checksum="5593FEFDAA9ED101" modified="2008-04-29" version="1">MSDVSQSASLSSIVAYIKLTNNCDQQTALIEAKEVMNNLVTMRQKGFITGWYFDEYGHLELLPSDSILKHITPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN2</accession>
    <name>B1KMN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AzlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3139</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325746.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3139"/>
    <dbReference type="EnsemblBacteria" id="ACA87410">
        <property type="protein sequence ID" value="ACA87410"/>
        <property type="gene ID" value="Swoo_3139"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3139"/>
    <dbReference type="eggNOG" id="COG1296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065777_1_1_6"/>
    <dbReference type="OMA" id="WPYKLGL"/>
    <dbReference type="OrthoDB" id="1866750at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="25041" checksum="03C0CC8E179C8BE7" modified="2008-04-29" version="1">MDSPSKETITTTALDAAIKGTLVILPLTIAVIPWGILAGSFALDAGLTPMESQAMSAVIFAGAAQLVALGMIKAGVGLTAILITTLLITSRHFLYGMAMREQISPMPLKWRLTLGFLLTDELFAIANQGKQHKLDPWFAFGGGFSFYLGWNIATAIGIIAGQTLPNLDSWGLDFAIAATFIAIVVPAIKKPSILICVLVSLVMSLICELMNIQAGLLIAALSGMACGTLYAKVTGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN5</accession>
    <name>B1KMN5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix type 11 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3142</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325749.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3142"/>
    <dbReference type="EnsemblBacteria" id="ACA87413">
        <property type="protein sequence ID" value="ACA87413"/>
        <property type="gene ID" value="Swoo_3142"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3142"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_7_1_6"/>
    <dbReference type="OMA" id="PDVLMTL"/>
    <dbReference type="OrthoDB" id="1654295at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="27259" checksum="E014C114A23CF549" modified="2008-04-29" version="1">MRRADRLFQIVQILRSRRLTTAQQLAERLEVSTRTVYRDIQDLSLSGIPIEGEAGVGYLLRQEVNVPPLMFNEAELEAIQVGMRMVQAWGGEELSSAAKQAMIKVEAVLPSRLQEYQSLMFAPDFYIDNDEFKFLDMLRKSSRLREYLLMDYRDANEEATQREIRPLAIYFWKGIWTLLAWCELRADFRNFRVDRIIHLTKLERHFAVSPGEEMHDYIALMEVKYGDESKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN8</accession>
    <name>B1KMN8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325752.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3145"/>
    <dbReference type="EnsemblBacteria" id="ACA87416">
        <property type="protein sequence ID" value="ACA87416"/>
        <property type="gene ID" value="Swoo_3145"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3145"/>
    <dbReference type="eggNOG" id="ENOG50301WU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176177_0_0_6"/>
    <dbReference type="OMA" id="ICNATSV"/>
    <dbReference type="OrthoDB" id="1899565at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046350">
        <property type="entry name" value="Cystatin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54403">
        <property type="entry name" value="SSF54403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="91" mass="9797" checksum="DAB05CC75DBC893E" modified="2008-04-29" version="1">MSNQNLGAYGPFTSEIDTQAKEAFSEAMEHFVGVDYSPVAVATQVVAGLNYAYFCNAQIPGLGSSVYPAMVNIYKPLDGDAVITHIQKVTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ1</accession>
    <name>B1KMQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325765.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3158"/>
    <dbReference type="EnsemblBacteria" id="ACA87429">
        <property type="protein sequence ID" value="ACA87429"/>
        <property type="gene ID" value="Swoo_3158"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3158"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_3_6"/>
    <dbReference type="OMA" id="HATVHEF"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="33659" checksum="37645809FDCF3539" modified="2008-04-29" version="1">MLDTLFPFKRNYLYRDGHKLQYVNEGEGEPVVMVHGNPSWSFYYRNVVTALSGKHQCIVPDHIGCGLSDKPDDSGYDYTLKNRIDDLEALLDHLNVKENITLVVHDWGGMIGMGYAARYPERIKRLVVLNTGAFHLPESKPFPWPLWICRNTLLGTALVRGFNAFSSIASYVGVKRKPMPAEIRKAYVAPFNSWANRISTLRFVQDIPLKPGDRNYELVSEIAASLPKFANVPTLICWGIKDFVFDKHFLAQWKVEMPHATVHEFADCGHYILEDASEEVVGHISDFISNDSLIANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMS3</accession>
    <name>B1KMS3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325787.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3180"/>
    <dbReference type="EnsemblBacteria" id="ACA87451">
        <property type="protein sequence ID" value="ACA87451"/>
        <property type="gene ID" value="Swoo_3180"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3180"/>
    <dbReference type="eggNOG" id="COG3310">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093792_0_0_6"/>
    <dbReference type="OMA" id="SPYPMLH"/>
    <dbReference type="OrthoDB" id="1450087at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009858">
        <property type="entry name" value="DUF1415"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07209">
        <property type="entry name" value="DUF1415"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="22071" checksum="CD95638E3507ED36" modified="2008-04-29" version="1">MTQQDTELQLIATHTQNWVERMIMKYNICPFARREVERRSIRYAVIDESKMHNVLEALIKECQYLDEHPETETTLFIIPRGFEGFYPYLDLVDIANDLLIDQDYEGVYQLASFHPDYCFEGEPMDEPSNYTNRSPYPTLHIIREVSMELALANYNDPESIPERNIAFAQKKGSDFFEKVLAGCMGKTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMU9</accession>
    <name>B1KMU9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OmpW family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3207"/>
    <dbReference type="EnsemblBacteria" id="ACA87477">
        <property type="protein sequence ID" value="ACA87477"/>
        <property type="gene ID" value="Swoo_3207"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3207"/>
    <dbReference type="eggNOG" id="COG3047">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042505_1_1_6"/>
    <dbReference type="OMA" id="DYMLTDN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005618">
        <property type="entry name" value="OMPW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36920">
        <property type="entry name" value="PTHR36920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03922">
        <property type="entry name" value="OmpW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766873" evidence="1">
        <location>
            <begin position="25"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="22917" checksum="0983D79F62DC1C80" modified="2008-04-29" version="1" precursor="true">MMKKNIVSGLVAALLSAGFASSVAAHQAGDIIVRAGAVVVAPNESSEQVATFGEFQVSNNTQLGLNFGYMLTDNIGIELLAATPFSHDVSLAGVGKIAETKQLPPTLVAQYYFGSANSKLRPYIGAGVNFTNFFDNEFTNDLDGALTDLSLSNSWGLAAQVGIDYQVNKNWLVNASVWYAQIDTDVKFNLGDAPVTIQTDIDPWVYMVSVGYTF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX4</accession>
    <name>RS17_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsQ</name>
        <name type="ordered locus">Swoo_4681</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327254.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMX4"/>
    <dbReference type="SMR" id="B1KMX4"/>
    <dbReference type="STRING" id="392500.Swoo_4681"/>
    <dbReference type="EnsemblBacteria" id="ACA88931">
        <property type="protein sequence ID" value="ACA88931"/>
        <property type="gene ID" value="Swoo_4681"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4681"/>
    <dbReference type="eggNOG" id="COG0186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073626_1_1_6"/>
    <dbReference type="OMA" id="HPMYGKF"/>
    <dbReference type="OrthoDB" id="2035880at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000143303" description="30S ribosomal protein S17">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <sequence length="82" mass="9350" checksum="58CA1D6084A270C0" modified="2008-04-29" version="1">MSDTIRTLQGRVLSNKMDKSITVAIERKVKHPLYGKFLKRTTKIHAHDEQNQCNAGDVVTIRECRPLSKTKSWTLVEVVTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN18</accession>
    <name>B1KN18_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Type II secretion system protein M</fullName>
            <shortName evidence="11">T2SS protein M</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">General secretion pathway protein M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_4725</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GSP M family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327292.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4725"/>
    <dbReference type="EnsemblBacteria" id="ACA88975">
        <property type="protein sequence ID" value="ACA88975"/>
        <property type="gene ID" value="Swoo_4725"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4725"/>
    <dbReference type="eggNOG" id="COG3149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118900_3_0_6"/>
    <dbReference type="OMA" id="PQGNKIQ"/>
    <dbReference type="OrthoDB" id="1991021at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007690">
        <property type="entry name" value="T2SS_GspM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023229">
        <property type="entry name" value="T2SS_M_periplasmic_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04612">
        <property type="entry name" value="T2SSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006291">
        <property type="entry name" value="GspM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103054">
        <property type="entry name" value="SSF103054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA88975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17381" checksum="A436DD073067918B" modified="2008-04-29" version="1">MDNLKAWWSGLELREQQLVGTCGVFLVVGILYWGIWTPIANAELDAERGLQAQQNTLNYVKQTANKIAGLKESGNKTSFRGSLSAAVNQSAGTYGLEITRMQPQGNKIQIWMDDVPFDALLAYLNDLVQGKGLSLDSIDLAESDLPGLVKVRRIQLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNC6</accession>
    <name>B1KNC6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0322</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322972.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0322"/>
    <dbReference type="EnsemblBacteria" id="ACA84623">
        <property type="protein sequence ID" value="ACA84623"/>
        <property type="gene ID" value="Swoo_0322"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0322"/>
    <dbReference type="eggNOG" id="COG3292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003758_2_0_6"/>
    <dbReference type="OMA" id="GNFKYYS"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="1">
        <location>
            <begin position="878"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="1084"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="1226"/>
            <end position="1481"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1481" mass="168605" checksum="E6B754F9120F6397" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNN6</accession>
    <name>B1KNN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Propionyl-CoA carboxylase</fullName>
            <ecNumber evidence="5">6.4.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.4.1.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325830.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3224"/>
    <dbReference type="EnsemblBacteria" id="ACA87494">
        <property type="protein sequence ID" value="ACA87494"/>
        <property type="gene ID" value="Swoo_3224"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3224"/>
    <dbReference type="eggNOG" id="COG4799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018822_0_1_6"/>
    <dbReference type="OMA" id="AYLPIMS"/>
    <dbReference type="OrthoDB" id="123223at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004658">
        <property type="term" value="F:propionyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="PTHR22855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="3">
        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="4">
        <location>
            <begin position="271"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="535" mass="58301" checksum="740DBDB9F7A85741" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP0</accession>
    <name>B1KNP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacid CoA-transferase, A subunit</fullName>
            <ecNumber evidence="1">2.8.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.3.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325834.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3228"/>
    <dbReference type="EnsemblBacteria" id="ACA87498">
        <property type="protein sequence ID" value="ACA87498"/>
        <property type="gene ID" value="Swoo_3228"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3228"/>
    <dbReference type="eggNOG" id="COG1788">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019942_2_0_6"/>
    <dbReference type="OMA" id="QLAPECI"/>
    <dbReference type="OrthoDB" id="1660857at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008260">
        <property type="term" value="F:3-oxoacid CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="234" mass="24777" checksum="9A6235ACCDEE903C" modified="2008-04-29" version="1">MAGLNKVVASYEEALAGLSNDMTVMVGGFGLCGIPEGLIAQMVKTGATGLTAISNNAGVDDFGLGLLLKTRQISTMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVADGKETREIDGRHYVLEPSLTADFALIRAWKADTMGNLVFRKTAANFNPMMATAGKITVVEAEHIVEAGELDPDHIHTPGIYVNRVIQGTFEKRIEQRTVKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ8</accession>
    <name>B1KNZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327346.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4780"/>
    <dbReference type="EnsemblBacteria" id="ACA89029">
        <property type="protein sequence ID" value="ACA89029"/>
        <property type="gene ID" value="Swoo_4780"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4780"/>
    <dbReference type="eggNOG" id="COG0401">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107649_7_1_6"/>
    <dbReference type="OMA" id="GVIHACF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="PTHR21659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA89029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="54" mass="5910" checksum="1B0ED37D97EDA454" modified="2008-04-29" version="1" precursor="true">MDTNKLLLVVIAILLPPVAVFLKSGVGKDLLINIILCLLFFIPGLLHALWVVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP02</accession>
    <name>B1KP02_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327350.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4784"/>
    <dbReference type="EnsemblBacteria" id="ACA89033">
        <property type="protein sequence ID" value="ACA89033"/>
        <property type="gene ID" value="Swoo_4784"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4784"/>
    <dbReference type="eggNOG" id="COG3212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129849_0_0_6"/>
    <dbReference type="OMA" id="AFDIENK"/>
    <dbReference type="OrthoDB" id="1622597at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="20287" checksum="3EF8730EC3C096C1" modified="2008-04-29" version="1" precursor="true">MARWLVGLVLFSSVGFSAPTWAEKSVLELLSDRQNLSPQSLMLKIEKQYSGVICEFEIDVENGELIYEVSIIDTQRETITEFEFKAKDGHLINQKVETLEADDKDGLKAVNLMEDIGQSFYSLVHKAMDGRHGHILEAQIDHDLGISYLEIKLIDETGKHRLAFDIQNQRPLPLLTWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP68</accession>
    <name>B1KP68_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pilus assembly protein PilO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322987.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0337"/>
    <dbReference type="EnsemblBacteria" id="ACA84638">
        <property type="protein sequence ID" value="ACA84638"/>
        <property type="gene ID" value="Swoo_0337"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0337"/>
    <dbReference type="eggNOG" id="COG3167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102444_1_0_6"/>
    <dbReference type="OMA" id="TARTFRY"/>
    <dbReference type="OrthoDB" id="1803493at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043107">
        <property type="term" value="P:type IV pilus-dependent motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007445">
        <property type="entry name" value="PilO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04350">
        <property type="entry name" value="PilO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016482">
        <property type="entry name" value="PilO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="205" mass="23324" checksum="551912F5254F3E95" modified="2008-04-29" version="1">MNLDLNQFNDIDFENVGAWPPLVKIVFAAILSICIFVASYFLFVSDAVAQLDKEQRTELQLREDFKSKYQLAANLKLYREQLAVMESQFAELLKMLPSKNEMPGLLDDLTFVATDSGLKIDSLDWREVIQRDFYIEFPISMSVTGEYHELGQLVSGVARLPRIVSLHDFVIKKSDTGGLGMEIMAKTYRFKEGSELPDKAKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA5</accession>
    <name>B1KPA5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="3 7">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0376</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + S-formylglutathione = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the esterase D family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="3 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0376"/>
    <dbReference type="ESTHER" id="shewm-b1kpa5">
        <property type="family name" value="A85-EsteraseD-FGH"/>
    </dbReference>
    <dbReference type="MEROPS" id="S09.A39"/>
    <dbReference type="EnsemblBacteria" id="ACA84675">
        <property type="protein sequence ID" value="ACA84675"/>
        <property type="gene ID" value="Swoo_0376"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0376"/>
    <dbReference type="eggNOG" id="COG0627">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056472_0_0_6"/>
    <dbReference type="OMA" id="TFMEDHL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="PTHR10061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0719">Serine esterase</keyword>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR614186-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="31988" checksum="574BAF624754CA28" modified="2008-04-29" version="1">MIANSVGDPSVTIENVSVNKSFDGWHKQYSHRSSVLNCEMRFAIYLPPQASNGEKVPVLYWLSGLTCTDENFMQKAGAQALAAELGIAIVAPDTSPRGDDVADDEGYDLGKGAGFYVNATQVPWSRHYQMYDYVVDELPKLIESMFPVSDKRSIAGHSMGGHGALVIALRNSDTYQSVSAFSPISNPINCPWGKKAFTAYLGRDTKTWSDYDASVLMRQATSFVPALVDQGDGDNFMVEQLKPEMLEAAASVSGYPLTLNIREGYDHSYYFISSYIENHLRFHAEHLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA6</accession>
    <name>B1KPA6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0377</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323025.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0377"/>
    <dbReference type="EnsemblBacteria" id="ACA84676">
        <property type="protein sequence ID" value="ACA84676"/>
        <property type="gene ID" value="Swoo_0377"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0377"/>
    <dbReference type="eggNOG" id="COG2076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133067_0_2_6"/>
    <dbReference type="OMA" id="GQAMKGM"/>
    <dbReference type="OrthoDB" id="1921902at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042221">
        <property type="term" value="P:response to chemical"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="108" mass="11517" checksum="D2A8845CD4413C14" modified="2008-04-29" version="1">MSWIFLILGVVAEALSHVALKATDGFTRPLPAALVILGHLTAFIFLGQAMKGMPVGIVHALWAGLAIVTVTLMSTLLYRQHLDTTAWIGMLLVAGGVMMINLSQGHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA9</accession>
    <name>B1KPA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323028.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0380"/>
    <dbReference type="EnsemblBacteria" id="ACA84679">
        <property type="protein sequence ID" value="ACA84679"/>
        <property type="gene ID" value="Swoo_0380"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0380"/>
    <dbReference type="eggNOG" id="COG2966">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036601_0_0_6"/>
    <dbReference type="OMA" id="MLSCGTG"/>
    <dbReference type="OrthoDB" id="1425894at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE" evidence="6">
        <location>
            <begin position="11"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE_2" evidence="7">
        <location>
            <begin position="275"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="406" mass="44204" checksum="5E5BCE6CC79C8E49" modified="2008-04-29" version="1">MDTQDFLVKRRFIIKLGKYLHKFGTPAYRLEAHLQAVSNFLGLEGYFLISPTAMTFVLQRDDEQEYNHVARVKPGELDLGSLARTDELVEELVSGKRTLDEALDRLDEIANKPNPYGSLLTLLAFGSSAGAFAMLMGTSWNDVFWSATLGFMVYGLVYRAERSKRMAEMLEPLAAILAAIITCGISQFDPSINIPVVILSGIIVFVPGLALTLGLAELAARDLISGTARIMDACMLLFKLYFGAIFGMVVGTAIFGEAIYFEPEPLPQIAVWSAVPILSMALVIIFKARMKDSPWGILAGIVAFCSSMLGAIYLGESIGIFFGAFAVGVYSNLFARWMKAPASIALLQGIVILVPGSKTYIGLNTLILGETMLNQSHIGTQIFLIFMSLVAGLIFANVAVSPRRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH6</accession>
    <name>B1KPH6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Substrate-binding region of ABC-type glycine betaine transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324475.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1845"/>
    <dbReference type="EnsemblBacteria" id="ACA86129">
        <property type="protein sequence ID" value="ACA86129"/>
        <property type="gene ID" value="Swoo_1845"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1845"/>
    <dbReference type="eggNOG" id="COG2113">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072510_0_0_6"/>
    <dbReference type="OMA" id="QVIAEEW"/>
    <dbReference type="OrthoDB" id="770506at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="OpuAC" evidence="2">
        <location>
            <begin position="27"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="334" mass="36543" checksum="A8F3004D7ADC72B2" modified="2008-04-29" version="1" precursor="true">MRNIILAAGLLGSIFTQQVSAEGECGKVTIADMNWSSASLIANVDRFILEHGYGCEAELLPGDTMPTSTSMIEKGEPDIAPEMWSNSVKELIEKAVSEKRLVIAGQSLSDGGEEGFWVPQYMVDKDPSLQTIAGVIANVKSFKHPEDPERGAFYGCPAGWGCQLSAENLYRALNLSDAGFDLIDPGSGAGLAGSIARAYEREKPWFGYYWAPTAVLGKYKMVKVDFGTGVDVEHFKACTSQAECADPKVTMYPKALVQTITTSDFTKKSSQGFDYLSKRAFTNEQMNGLLAWMEDNQADGDIAAEYFLTNYEDIWTQWVAADVAAKVKQAIKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPN5</accession>
    <name>B1KPN5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324534.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1904"/>
    <dbReference type="EnsemblBacteria" id="ACA86188">
        <property type="protein sequence ID" value="ACA86188"/>
        <property type="gene ID" value="Swoo_1904"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1904"/>
    <dbReference type="eggNOG" id="ENOG502Z91E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068897_0_0_6"/>
    <dbReference type="OMA" id="WYEVGER"/>
    <dbReference type="OrthoDB" id="937464at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="344" mass="38459" checksum="4C46BC20176CE817" modified="2008-04-29" version="1">MFYDQNLAIRYPKGPFAMWSVYSFTGASILASIVFSLLLFLSIDDDPLMQFLFGGLAIVFELGKFFAWYEVGERHARRNYSGMIFALGFYAVLAAISIGGSVGGINSATNKAQSHVALHQSKVNAFDMQIAAIDKQIALNNVAAEKYIQMERIATGVVRIQNENKRLREEQQKLAVQRDSLPLAEQGSVVGLIDSLASFLHTSPHTAQLGLVVFLSILLDFFAAFFVGLIGEENRFRHQYRHMKPITIDSFTSGEMKEPEMLSHFTPTINSEFDGTACNEPNKTAYERVIEALSTQQVMCSKRAVITQLKLKPDEVDVIFTQLFNEGIVSKKANNHFQWHGLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ4</accession>
    <name>B1KPQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3318"/>
    <dbReference type="EnsemblBacteria" id="ACA87587">
        <property type="protein sequence ID" value="ACA87587"/>
        <property type="gene ID" value="Swoo_3318"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3318"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_2_6"/>
    <dbReference type="OMA" id="VKSRMRY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="38"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="23700" checksum="2BCD7C6BF89D6806" modified="2008-04-29" version="1">MSLENRVAEALDKRGEADSDQALMLQYMQGDMSAFESLYQKHKGGLYRYFVRQIGDLQLAEDLYQDTWGRVIKAAASYEPSAKFTTWLYRIAHNLLIDHVRAVKPVDHFSEVFTEEQDADSFLPSDEQAPQTQFIAWTKAQLLKHCISLLPTVQKEALLLNMEAGFTAGTIAEVVGTSLEATKSRIRYANQSLKTCVMNKWQEVENER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ5</accession>
    <name>B1KPQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3319</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325924.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3319"/>
    <dbReference type="EnsemblBacteria" id="ACA87588">
        <property type="protein sequence ID" value="ACA87588"/>
        <property type="gene ID" value="Swoo_3319"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3319"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019123_0_0_6"/>
    <dbReference type="OMA" id="MINYFDY"/>
    <dbReference type="OrthoDB" id="692608at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021908">
        <property type="entry name" value="DUF3520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022156">
        <property type="entry name" value="Uncharacterised_YfbK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12034">
        <property type="entry name" value="DUF3520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12450">
        <property type="entry name" value="vWF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765115" evidence="2">
        <location>
            <begin position="33"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="253"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="640" mass="69658" checksum="8F0177215C527272" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPZ1</accession>
    <name>MTNC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enolase-phosphatase E1</fullName>
            <ecNumber evidence="1">3.1.3.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mtnC</name>
        <name type="ordered locus">Swoo_4855</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="3.1.3.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.77" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327421.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPZ1"/>
    <dbReference type="SMR" id="B1KPZ1"/>
    <dbReference type="STRING" id="392500.Swoo_4855"/>
    <dbReference type="EnsemblBacteria" id="ACA89104">
        <property type="protein sequence ID" value="ACA89104"/>
        <property type="gene ID" value="Swoo_4855"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4855"/>
    <dbReference type="eggNOG" id="COG4229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023273_0_0_6"/>
    <dbReference type="OMA" id="QLKGHVY"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00876"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00877"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043715">
        <property type="term" value="F:2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043716">
        <property type="term" value="F:2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043874">
        <property type="term" value="F:acireductone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01629">
        <property type="entry name" value="HAD_EP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01681">
        <property type="entry name" value="Salvage_MtnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023943">
        <property type="entry name" value="Enolase-ppase_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00044">
        <property type="entry name" value="enolase-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01691">
        <property type="entry name" value="enolase-ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0486">Methionine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000357412" description="Enolase-phosphatase E1">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01681"/>
        </source>
    </evidence>
    <sequence length="225" mass="25305" checksum="710759A9C84EEA03" modified="2008-04-29" version="1">MGIRAIVVDTAGTTTDLNFIKDTLFTYSAKALPDFLKENETNVLVDNCICDVRDIALEPDASLERVVEILQQWVEEDRKATPLKTLQGLIWKQGYARGEFTGHIFPDFIDTIESIKQQNIRIYSFSSGSAEAQKLLFSHSDGGDLTPHFDGHFDTRTGNKLFKQAYCNIINTISLAPKQVLFISDVIEELKAAEEAGMRTLQMVRSADQRTGNFKQIASFKELTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ43</accession>
    <name>B1KQ43_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobyrinic acid ac-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327472.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4907"/>
    <dbReference type="EnsemblBacteria" id="ACA89156">
        <property type="protein sequence ID" value="ACA89156"/>
        <property type="gene ID" value="Swoo_4907"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4907"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037612_1_3_6"/>
    <dbReference type="OMA" id="VQCEYFA"/>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="2"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="28692" checksum="156260350979B4C7" modified="2008-04-29" version="1">MGKVIAVANQKGGVGKTTTCVNLAASLAATKRKVLLIDLDPQGNATMGSGIDKYSVENTAYELLVDEKSFDEVVYRDTSGKYDLIAGNGDVTAAEIKLMEFFAREIRLRNALAPVKDEYDFIFIDCPPSLNMLTVNAMSAADSVLVPMQCEYYALEGLTALMDTISKIGAMVNPGLCIEGILRTMYDPRNRLANDVSDQLKQHFGEKVYRTVIPRNVRLAEAPSFGAPAMYYDKSSAGAKAYLSLAGEIIRRAEQHDLQGEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC8</accession>
    <name>B1KQC8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster assembly protein CyaY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cyaY</name>
        <name evidence="4" type="ordered locus">Swoo_0485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the frataxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323132.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0485"/>
    <dbReference type="EnsemblBacteria" id="ACA84783">
        <property type="protein sequence ID" value="ACA84783"/>
        <property type="gene ID" value="Swoo_0485"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0485"/>
    <dbReference type="eggNOG" id="COG1965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080880_3_0_6"/>
    <dbReference type="OMA" id="EPMHEIW"/>
    <dbReference type="OrthoDB" id="1812841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00142">
        <property type="entry name" value="CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="PTHR16821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="SSF55387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="12337" checksum="7109FB5B9334962F" modified="2008-04-29" version="1">MAMTDTEFHQLADEMFQAIDNAIEIAIDEQDADVDIDASGNVLQLTFEDTSKIVINKQEPLHQIWVATKFGGYHFSFVEGKWIDERNGGEFMPFVIDSILKQGDIQLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQF1</accession>
    <name>B1KQF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Succinate dehydrogenase or fumarate reductase, flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_0509</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323154.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0509"/>
    <dbReference type="EnsemblBacteria" id="ACA84806">
        <property type="protein sequence ID" value="ACA84806"/>
        <property type="gene ID" value="Swoo_0509"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0509"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_6_2_6"/>
    <dbReference type="OMA" id="WRRIKVP"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="12">
        <location>
            <begin position="7"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="13">
        <location>
            <begin position="468"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="654"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA84806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="674" mass="74124" checksum="F27E0AF08E9E45E8" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH0</accession>
    <name>B1KQH0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324555.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86209">
        <property type="protein sequence ID" value="ACA86209"/>
        <property type="gene ID" value="Swoo_1925"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1925"/>
    <dbReference type="eggNOG" id="ENOG502ZVBT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2425286_0_0_6"/>
    <dbReference type="OMA" id="FEIYNNA"/>
    <dbReference type="OrthoDB" id="2048958at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="10081" checksum="F394059AFC289F00" modified="2008-04-29" version="1">MNRIKEAQEHLKNEFKLYNDASSKKLPDLELESPEKLEALLESVTRRESLSRDKKTPPATKLKSALADNLLLLDNFDIKKAKEAGKAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ2</accession>
    <name>B1KQJ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lytic murein transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1947</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324577.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1947"/>
    <dbReference type="CAZy" id="GH103">
        <property type="family name" value="Glycoside Hydrolase Family 103"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86231">
        <property type="protein sequence ID" value="ACA86231"/>
        <property type="gene ID" value="Swoo_1947"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1947"/>
    <dbReference type="eggNOG" id="COG2951">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035402_0_2_6"/>
    <dbReference type="OMA" id="WPADGYP"/>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043426">
        <property type="entry name" value="MltB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011970">
        <property type="entry name" value="MltB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031304">
        <property type="entry name" value="SLT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163">
        <property type="entry name" value="PTHR30163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13406">
        <property type="entry name" value="SLT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02283">
        <property type="entry name" value="MltB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765127" evidence="1">
        <location>
            <begin position="24"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="SLT_2" evidence="3">
        <location>
            <begin position="26"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="337"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="395" mass="43815" checksum="72CD3846564DABED" modified="2008-04-29" version="1" precursor="true">MIKNVPLASLLLFSSLSTPLAFATDFPSCVVELQKTAKSQGLSADTIENTLGKVKYVARVIELDKKQPEFSQTFDNYFSKRVTDWRVKEGRRLLAENRELLNQLKDKYGVPPQYLMAFWGLETNFGSYKGKMPVLDSLATLACDPRRSGYFTGELMKALKLKEEYQFEASEMVGSWAGAMGHTQFMPSAYTAYAVDGDGDGKADLWNSRADALTSAANFLQQLGWQRNERWGREVTLPDNFSYEYLGKRHEQALVKWAELGVMKNDGKPISTPDMKAALYLPAGHTGPAFLGYKNFDVIMRWNRSTFYVIAVGHLADRINGGVSLTVAPPKQDNLSRARVKQLQAKLNEKGFDVGKPDGVLGANSKSGLREFQRSAGLVADGFPSEASFNALGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR27</accession>
    <name>B1KR27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323192.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84844">
        <property type="protein sequence ID" value="ACA84844"/>
        <property type="gene ID" value="Swoo_0548"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0548"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_3_6"/>
    <dbReference type="OMA" id="FHNDSIR"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="16433" checksum="36D4BF698A0678C8" modified="2008-04-29" version="1">MFFLKELPTEVMLDKYTSDLTNGEKNSIIEALRIMRQASLLIRSIETYFSVHDLSQLRFLILIVIDREPNRSSLYPHEIASRLDVSRPVLTRTLKSLIEDGLLTSSNDETDKRAKKITLTKKGVTCLSKVIPGYFNEINKLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRA4</accession>
    <name>B1KRA4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2027</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324657.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2027"/>
    <dbReference type="EnsemblBacteria" id="ACA86311">
        <property type="protein sequence ID" value="ACA86311"/>
        <property type="gene ID" value="Swoo_2027"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2027"/>
    <dbReference type="eggNOG" id="ENOG5034221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_483033_0_0_6"/>
    <dbReference type="OMA" id="TSRESTW"/>
    <dbReference type="OrthoDB" id="410471at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="511"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="564" mass="63419" checksum="15CAC3B57B98D1AF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRE5</accession>
    <name>IHFA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integration host factor subunit alpha</fullName>
            <shortName evidence="1">IHF-alpha</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ihfA</name>
        <name evidence="1" type="synonym">himA</name>
        <name type="ordered locus">Swoo_2068</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324697.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRE5"/>
    <dbReference type="SMR" id="B1KRE5"/>
    <dbReference type="STRING" id="392500.Swoo_2068"/>
    <dbReference type="EnsemblBacteria" id="ACA86352">
        <property type="protein sequence ID" value="ACA86352"/>
        <property type="gene ID" value="Swoo_2068"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2068"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_1_3_6"/>
    <dbReference type="OMA" id="IYVRGFG"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13835">
        <property type="entry name" value="IHF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00380">
        <property type="entry name" value="IHF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005684">
        <property type="entry name" value="IHF_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00987">
        <property type="entry name" value="himA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0810">Translation regulation</keyword>
    <feature type="chain" id="PRO_1000122168" description="Integration host factor subunit alpha">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="97" mass="10989" checksum="8F44DDCB25F4A2FF" modified="2008-04-29" version="1">MALTKAEMAEHLFETLGINKRVAKEMVEAFFEEIRQALESGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPISARRVVTFRPGQKLKSRVEEANAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF4</accession>
    <name>B1KRF4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ni_hydr_CYTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324706.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86361">
        <property type="protein sequence ID" value="ACA86361"/>
        <property type="gene ID" value="Swoo_2077"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2077"/>
    <dbReference type="eggNOG" id="COG3038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121451_0_0_6"/>
    <dbReference type="OMA" id="TAYYRYW"/>
    <dbReference type="OrthoDB" id="1940783at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="14"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="22146" checksum="0DB884175CFC941F" modified="2008-04-29" version="1">MTNKMPVAKSLLCSRVSRKLHWCLVFSVFMTYITAYYRYWYTSQSEVANWYLLLVHINFGILVLVLTVVMLTYRMLKRSAHVTKSSVLAARVVHYCLYFILLMMPIAAYIGTAVDIPLLGAVYLPGFFRFEVVEHWIREELGMLMIAFIEPFAIFHKDVGADIILPFLLLGHIGAAAVHLCQQDGMSCNNEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG5</accession>
    <name>B1KRG5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="9">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisH</fullName>
            <shortName evidence="9">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisH</name>
        <name evidence="12" type="ordered locus">Swoo_2088</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EC" id="3.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324717.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2088"/>
    <dbReference type="MEROPS" id="C26.965"/>
    <dbReference type="EnsemblBacteria" id="ACA86372">
        <property type="protein sequence ID" value="ACA86372"/>
        <property type="gene ID" value="Swoo_2088"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2088"/>
    <dbReference type="eggNOG" id="COG0118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071837_0_0_6"/>
    <dbReference type="OMA" id="WVYFVHS"/>
    <dbReference type="OrthoDB" id="1726024at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="216" mass="23185" checksum="0DE9875D3C240B49" modified="2008-04-29" version="1">MSQTNTTVIIDTGCANLNSVRYAFERLTDDVLVTDNHEAIKAADRVVLPGVGTAGAAMASLKNKQLIELIQGLTQPVLGVCLGMQMMGSLSKEQGGKLVDCECLGLIPTEVTELDSQGQPLPHMGWNQIEVSDHPLFDGIASGSYLYFVHSYRAPLSEYTIANSQYGETFSAAIAKDNFMGVQFHPEKSAAVGSAILKNFLALDKGSLNMKLQEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK0</accession>
    <name>B1KRK0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3501"/>
    <dbReference type="EnsemblBacteria" id="ACA87765">
        <property type="protein sequence ID" value="ACA87765"/>
        <property type="gene ID" value="Swoo_3501"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3501"/>
    <dbReference type="HOGENOM" id="CLU_2755641_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="70" mass="7996" checksum="98759C6EDCC9872A" modified="2008-04-29" version="1">MSRYADSLLAEISLLDHPDQHVEALRSMESACHVKAYGDLFLETLTGYEWPDKVSQLRSLCQAQISSRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRN5</accession>
    <name>B1KRN5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326133.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3536"/>
    <dbReference type="EnsemblBacteria" id="ACA87800">
        <property type="protein sequence ID" value="ACA87800"/>
        <property type="gene ID" value="Swoo_3536"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3536"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131496_13_2_6"/>
    <dbReference type="OMA" id="CISFEVS"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="31"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="91" mass="10719" checksum="800068F0C7C7FEB7" modified="2008-04-29" version="1">MAKVTLKGFILVPESELEIIKSELIIHKLLTLEEPGCITFDVTENSENPFRFDVYEEFIDKSTFEYHQARVKASHWGKITVHIERYYEIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCY5</accession>
    <name>B1KCY5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="9">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glycyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="9">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glyQ</name>
        <name evidence="10" type="ordered locus">Swoo_0013</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0013"/>
    <dbReference type="EnsemblBacteria" id="ACA84314">
        <property type="protein sequence ID" value="ACA84314"/>
        <property type="gene ID" value="Swoo_0013"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0013"/>
    <dbReference type="eggNOG" id="COG0752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057066_1_0_6"/>
    <dbReference type="OMA" id="SYYQFQV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00733">
        <property type="entry name" value="GlyRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="287" mass="32825" checksum="1ECAC89FC7F9A10E" modified="2008-04-29" version="1">MTLQEYWAQQGCAIVQPLDMEVGAGTFHPQTFLRSLGPEPMSSAYVQPCRRPTDGRYGENPNRLQHYYQYQVVLKPSPSNIQELYLGSLEALGVDMNVHDVRFVEDNWESPTLGAWGLGWEVWLNGMEVSQFTYFQQVGGLECSPVTGEITYGLERLAMYIQEVDSVYDLVWTDGPMGKVMYGDIFHQNEVEQSTYNFEHANVDVLFKMFDDCEVACQRLLTLEKPLPLPAYEQVMKASHAFNLLDARHAISVTERQRYILRVRTMAKGVAESYYQAREALGFPMCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD03</accession>
    <name>B1KD03_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carbonic anhydrase, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322699.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0049"/>
    <dbReference type="EnsemblBacteria" id="ACA84350">
        <property type="protein sequence ID" value="ACA84350"/>
        <property type="gene ID" value="Swoo_0049"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0049"/>
    <dbReference type="eggNOG" id="COG0663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064827_7_0_6"/>
    <dbReference type="OMA" id="YVTIGHN"/>
    <dbReference type="OrthoDB" id="1242595at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="180" mass="19398" checksum="31C85DE044B2A8B3" modified="2008-04-29" version="1">MSSSLRSYKGVTPTLHQDVYIDEACVLVGDIDLDDDSSIWPLVAARGDVNHMKIGKRTNVQDGTILHVTRKSASNPNGHPLLIGDDVTVGHKAMLHGCTVGNRILIGMGAIILDGAIVEDDVILGAGSLVPPNKVLKSGFLYVGSPAKQIRPLTEAELKFLPESAENYVRLKNEYLQESV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD28</accession>
    <name>PROB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamate 5-kinase</fullName>
            <ecNumber evidence="1">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyl kinase</fullName>
            <shortName evidence="1">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">proB</name>
        <name type="ordered locus">Swoo_3599</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326196.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KD28"/>
    <dbReference type="SMR" id="B1KD28"/>
    <dbReference type="STRING" id="392500.Swoo_3599"/>
    <dbReference type="EnsemblBacteria" id="ACA87863">
        <property type="protein sequence ID" value="ACA87863"/>
        <property type="gene ID" value="Swoo_3599"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3599"/>
    <dbReference type="eggNOG" id="COG0263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025400_2_0_6"/>
    <dbReference type="OMA" id="TVIHRDN"/>
    <dbReference type="OrthoDB" id="1480250at2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0641">Proline biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000125263" description="Glutamate 5-kinase">
        <location>
            <begin position="1"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="1">
        <location>
            <begin position="280"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="173"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="215"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <sequence length="372" mass="39799" checksum="D75F4C5B1DB454BB" modified="2008-04-29" version="1">MNLSEIGYRRVVVKLGTSVLTSGSKQLDKAHMVELARQMSALMKAGVEVVLCTSGAIAAGREHLGYPKLADTVANKQLLAAVGQSQLILAWSQLFSIYGLHVGQLLLTQADLHDRERYLNARDSLNALLNNGIIPIINENDAVATNEIKVGDNDNLSARAALLCHADLLILLTDQQGLFDSDPRSNPDAKLIKQVVNIDDSLRQLAGGAVSGLGTGGMATKLEAADIARRAGIEVVIASGHRRQVILNAVCKEDVGTHFTALENPLESRKQWILAGQAAKGKLVLDVGAIKAVTEKGRSLLSKGVVSVIGEFDRGTTLQLIDSDGRECARGISRYSAGDLNKIVGKHSDEIESLLGYDYGDAVVHRNDMVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD63</accession>
    <name>B1KD63_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alkanal monooxygenase</fullName>
            <ecNumber evidence="7">1.14.14.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Bacterial luciferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3636</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Light-emitting reaction in luminous bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a long-chain fatty aldehyde + FMNH2 + O2 = a long-chain fatty acid + FMN + 2 H(+) + H2O + hnu</text>
            <dbReference type="Rhea" id="RHEA:17181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the bacterial luciferase oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.3" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326231.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3636"/>
    <dbReference type="EnsemblBacteria" id="ACA87898">
        <property type="protein sequence ID" value="ACA87898"/>
        <property type="gene ID" value="Swoo_3636"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3636"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_3_0_6"/>
    <dbReference type="OMA" id="WVDLEVF"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047646">
        <property type="term" value="F:alkanal monooxygenase (FMN-linked) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008218">
        <property type="term" value="P:bioluminescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01096">
        <property type="entry name" value="Alkanal_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033924">
        <property type="entry name" value="Alkanal_monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018235">
        <property type="entry name" value="Bacterial_luciferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002103">
        <property type="entry name" value="Luciferase_bac/NFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00089">
        <property type="entry name" value="LUCIFERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00494">
        <property type="entry name" value="BACTERIAL_LUCIFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="5 7" id="KW-0455">Luminescence</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0599">Photoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="37179" checksum="97CBA5F21FB30BF0" modified="2008-04-29" version="1">MKFGLFFLNIQVDESSAEETLDNMVKTVTLIDSDEYYFDKVLINEHHFSKNGIIGAPITAAGFLLGLTNKLHIGSLNQIITTHHPVRIAEEASLLDQMSEGRFILGFSDSENKFEMAFFKRQLSSQQQQFEACYDIINDALTTGFCHPQNDFYDFPKVSINPHCVSENGPEQYVLASSKEVVTWAAKRALPLTFKWEDSLTDKERYANLYNETAKLFNVDVSNVNHQLTLIANLNDDGDIARQEVKQYLKSYITERYPDIDHAEKINTIIEENAIGTNDDYYESSLLAIDKTGAKTILLSFESMRDQNKVKNIIDMVNQKIFKNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD74</accession>
    <name>B1KD74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VanZ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3647"/>
    <dbReference type="EnsemblBacteria" id="ACA87909">
        <property type="protein sequence ID" value="ACA87909"/>
        <property type="gene ID" value="Swoo_3647"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3647"/>
    <dbReference type="eggNOG" id="COG5652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096028_3_4_6"/>
    <dbReference type="OMA" id="KWALALM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="2">
        <location>
            <begin position="33"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="121" mass="14106" checksum="EBC6C95D970466F4" modified="2008-04-29" version="1" precursor="true">MISKRNIFKLALIAALIAISYLVFSRPSYPQLIPHMDKVGHLVSFFCLSYLTYLAFKPRWGFLAITLACYAIFIELVQYWLPYRSASLADFAADMLGVLLFYFCHWSYLRYFQASHLSEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL2</accession>
    <name>B1KDL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sortase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324754.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2125"/>
    <dbReference type="EnsemblBacteria" id="ACA86409">
        <property type="protein sequence ID" value="ACA86409"/>
        <property type="gene ID" value="Swoo_2125"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2125"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045680_6_0_6"/>
    <dbReference type="OMA" id="PWPWADT"/>
    <dbReference type="OrthoDB" id="1022681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05828">
        <property type="entry name" value="Sortase_D_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041999">
        <property type="entry name" value="Sortase_D_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022445">
        <property type="entry name" value="Sortase_proteobact_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03784">
        <property type="entry name" value="marine_sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01076">
        <property type="entry name" value="sortase_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="22566" checksum="9F2F118B90B5CC50" modified="2008-04-29" version="1" precursor="true">MLKSVHFHRAIIFMLLALAGIFLGQGVYMQAKAHFAQYLIEQAWKRTLVDQQPHKPWSWADTYPVAQMTFIDEQGDKEGLLTGDSMYVLEGASGRNLAFGPAQLQDGRESWRGESRIIAGHNDTHFSILEGVKQGKQIKLQERDGTEVIYQVVGTQVVHESDTQVLNSDSDKRLTLITCYPFHSLTTGGPLRFIVYAEVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDP0</accession>
    <name>B1KDP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2153</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324782.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2153"/>
    <dbReference type="EnsemblBacteria" id="ACA86437">
        <property type="protein sequence ID" value="ACA86437"/>
        <property type="gene ID" value="Swoo_2153"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2153"/>
    <dbReference type="eggNOG" id="COG2989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020360_5_0_6"/>
    <dbReference type="OMA" id="YWTAWID"/>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PG_binding_1" evidence="4">
        <location>
            <begin position="146"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="229"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="461" mass="53120" checksum="6C8EE75C1F347938" modified="2008-04-29" version="1">MHKGNRVGYVIMALFIQLCATPCVLALDKNSAAINALRYQVQLISLIDPSFSKYNQLLTQDLEEEQLDLTNDIQLEVANFWRSVKIQSRGEGGSDDLYRNVISLEPSSSDYLPISNRIRYLLWVEQTESWQPLVLDIWLKEGDINPAVKVISRRLNWLGDLNFLDPDNSVMTSELVRGVLNFQRRHGLKQDGVIGPETLRWINLTPKKRAALLAENFISKSSYLSTIGPRFLLVNIPAFEMVLVDKGQVQLESRVIVGKPYRQTPRLSSYISNMVLNPSWRVPRTLLRRDLLPKVRKDGAYISEHNFDVFNSAGDEIVKSPEEWQTLAGGRFPYRLVQKPGKDNTLGRYKFYFKNEYNVYLHDTYDKALFEESNRALSSGCIRVEKVESLANWLASNLVSDKQTWVDLQTERDKTQWFAFDNFLAVHLVYWTAWVDESGLAQFRNDIYHQNSMPKLASIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ3</accession>
    <name>B1KDQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324794.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2167"/>
    <dbReference type="EnsemblBacteria" id="ACA86450">
        <property type="protein sequence ID" value="ACA86450"/>
        <property type="gene ID" value="Swoo_2167"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2167"/>
    <dbReference type="eggNOG" id="COG3308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122357_1_1_6"/>
    <dbReference type="OMA" id="YAWASFI"/>
    <dbReference type="OrthoDB" id="1894946at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018643">
        <property type="entry name" value="DUF2069_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09842">
        <property type="entry name" value="DUF2069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="123" mass="13908" checksum="75462EFAF4119DDE" modified="2008-04-29" version="1">MSTDMLFKLCRAGYLLLVLLLAGWFVNKGVTGEYSLPFALLWIIPILLPLKGVIQGKPYTYAWGSFIICLYMLHGLTLLYVTEEYFAFALIEVLLLGALLIGFPFYARLRGRELGLGLKKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX7</accession>
    <name>B1KDX7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326311.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3719"/>
    <dbReference type="EnsemblBacteria" id="ACA87979">
        <property type="protein sequence ID" value="ACA87979"/>
        <property type="gene ID" value="Swoo_3719"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3719"/>
    <dbReference type="eggNOG" id="ENOG50339YA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108835_3_0_6"/>
    <dbReference type="OMA" id="CENAKHN"/>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764730" description="DUF4124 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="3">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="16937" checksum="93728B872D172730" modified="2008-04-29" version="1" precursor="true">MLMFKKLILLSLSLTHTFTVSATVIHKWVDKDGVTHYSQQPPENTDSSKLYSEDIEQKPIGFIQPKVRESNAAVQTEDEKNAEAIKKQSSEQAAAICENAKQNLNILTSHSRLKNKDEKTGEMVSMREEDRQEQISTQKERIKLFCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA0</accession>
    <name>B1KEA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0791</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323433.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0791"/>
    <dbReference type="EnsemblBacteria" id="ACA85086">
        <property type="protein sequence ID" value="ACA85086"/>
        <property type="gene ID" value="Swoo_0791"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0791"/>
    <dbReference type="eggNOG" id="COG3489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050043_0_0_6"/>
    <dbReference type="OMA" id="QGFHTME"/>
    <dbReference type="OrthoDB" id="1385990at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd14658">
        <property type="entry name" value="Imelysin-like_IrpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018976">
        <property type="entry name" value="Imelysin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034982">
        <property type="entry name" value="Imelysin-like_IrpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038352">
        <property type="entry name" value="Imelysin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09375">
        <property type="entry name" value="Peptidase_M75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764336" evidence="2">
        <location>
            <begin position="22"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M75" evidence="3">
        <location>
            <begin position="54"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="381" mass="40825" checksum="F81BEB77C0D41142" modified="2008-04-29" version="1" precursor="true">MKQLKYSAIAIALISTLAACGGSGSDDTTPTPVDDKFEFAATEMITNLTDDVIVSGYASLATKGEEMLLATQTLVSNKTQANLLAAQEAWKAARLPWEQGESHIFGPVDSLGIDPHLDSWPLNTTDLTTVLASNAGFDAETIKGWNDDVQGFHTMEYLLFGDGVADNEKAIAELTQAESEYLMGLAEVFRDYTKTLDDAWQVSHDGSGKAYGELVKTPGSEGNTFYSSQVGVIEELINGMIGIVDEVGNGKIADPFGTSAATADTSKVESQYSWNSLTDFSDNIIGVRNVYQGELTGAADKQGIIDFVKAADEVLALRVGSEIDDAIIKIKAISGSNNMPFRQAISDAEGRVRVQTAVDALTKLQTSLESDVLPLLSKWKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEC8</accession>
    <name>B1KEC8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324850.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2225"/>
    <dbReference type="EnsemblBacteria" id="ACA86506">
        <property type="protein sequence ID" value="ACA86506"/>
        <property type="gene ID" value="Swoo_2225"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2225"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040940_5_1_6"/>
    <dbReference type="OMA" id="YYIWGAT"/>
    <dbReference type="OrthoDB" id="1623169at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="21687" checksum="BA156CCDEC0CFFC6" modified="2008-04-29" version="1">MNLAELRVRYNFQALTDLISPPISSELRQAAVLIAFTQVDNDTHLILTRRPMHLRSHPGQISFPGGKVEKSDINDIATALREAEEEIALKISNVDVLGQHPKYKTFTGFEITPVFGIVKQSFVPELDPGEVDYLFTIPLTFLLDKRNRKHYLYRRHGTQHTVHFIQYKHHMIWGATAAIIEQLCQQITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEK6</accession>
    <name>B1KEK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3762</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326353.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3762"/>
    <dbReference type="EnsemblBacteria" id="ACA88021">
        <property type="protein sequence ID" value="ACA88021"/>
        <property type="gene ID" value="Swoo_3762"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3762"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="VWGWDFG"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="27176" checksum="C70A0317EFCCF47C" modified="2008-04-29" version="1">MQNPHILIVEDEAVTRNTLRSIFEAEGYVVTEANDGAEMHKAMQENKINLVVMDINLPGKNGLLLARELREINNIGLIFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLTRVNSTGAESEEKSAVEFYRFNGWSLEINSRSLVSPQGESYKLPRSEFRAMLHFVENPGKILSRADLLMKMTGRELKPHDRTVDVTIRRIRKHFESLPDTPEIIATIHGEGYRFCGNLEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEK8</accession>
    <name>B1KEK8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartokinase</fullName>
            <ecNumber evidence="10">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_3764</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326355.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3764"/>
    <dbReference type="EnsemblBacteria" id="ACA88023">
        <property type="protein sequence ID" value="ACA88023"/>
        <property type="gene ID" value="Swoo_3764"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3764"/>
    <dbReference type="eggNOG" id="COG0527">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009116_6_0_6"/>
    <dbReference type="OMA" id="LMSCGEV"/>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042199">
        <property type="entry name" value="AsparK_Bifunc_asparK/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00656">
        <property type="entry name" value="asp_kin_monofn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="12">
        <location>
            <begin position="3"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="221"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="257"/>
            <end position="258"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000726-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA88023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="450" mass="48491" checksum="994B296B6A116C46" modified="2008-04-29" version="1">MSLIVAKFGGTSVADYSAMSRCADIIIANPNTRVVVVSASSGVTNLLVELTQEQTTDERRKQLIKQIAHIQYQILDDLGRPQEVAARLDSVLSRIAVLSESLSSNRCKATMDELLAQGEQCSSALFAAVLREKGETASAFDVRQVMRTDSHFGRAEPQIETIAKLANEQLFPLLSSQRIVTQGFIGADEAGSTTTLGRGGSDYSAALLAEALKASAVEIWTDVAGIYTTDPRLAPNASPIAEISFNEAAEMATFGAKVLHPATILPAVRQKIQVFVGSSREPERGGTWIRHQVEEAPVYRAVAVRRDQTLLNLHSLQMLHAQGFLAETFATLARHKISVDLITTSEVNVSLTLDKTGSDSAGNGLLSEALLQELSQHCRVRVEDSLALVAIVGNKIASTPGVCRRVFEVLEPHNVRMICQGASPHNLCVLVAESEAAQVVSALHENLFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES9</accession>
    <name>B1KES9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326424.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3835"/>
    <dbReference type="EnsemblBacteria" id="ACA88094">
        <property type="protein sequence ID" value="ACA88094"/>
        <property type="gene ID" value="Swoo_3835"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3835"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_12_2_6"/>
    <dbReference type="OMA" id="TPIEQPR"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="18"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="113"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="21714" checksum="733E788AE911D007" modified="2008-04-29" version="1">MLKETLIYKTYLASREGIARVVSRIVPPHEIEDIVQETYVRLCQVENKESINSAKSFMYKMARNLALDHQKRANVRLVDSVDDWHEFEKALCDRHDEVYDKAITSLEFDNFCEAVRLLPLQCRKVFVLKKVYGYSQREIAEELELSESTVEKHISQGIKRCTVFMRQAQKGKTQVSATTSGKRGGAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF00</accession>
    <name>B1KF00_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85151">
        <property type="protein sequence ID" value="ACA85151"/>
        <property type="gene ID" value="Swoo_0857"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0857"/>
    <dbReference type="HOGENOM" id="CLU_2720117_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="72" mass="7784" checksum="0BB7A431BC85213A" modified="2008-04-29" version="1">MASVPSTHTVATVLGIYQASLNSKYCDYLCKPSFALKKRGAQKAEGVIVLSFVCLLLFSASPHFMVMDEVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF26</accession>
    <name>B1KF26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323524.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85177">
        <property type="protein sequence ID" value="ACA85177"/>
        <property type="gene ID" value="Swoo_0883"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0883"/>
    <dbReference type="eggNOG" id="ENOG50344HY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1546554_0_0_6"/>
    <dbReference type="OMA" id="KAWKRWH"/>
    <dbReference type="OrthoDB" id="1886887at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19115" checksum="F29601DC40845D14" modified="2008-04-29" version="1" precursor="true">MNNKRLTSLLACTLLATACGSDSNDSNDGGEIAPPPVATTIDIDKATSIQIELTSFEGASGALSFNLSDNEKQAITQAKDYKIIYFGFPEQNSKINNPKGWQRWHLTNSYSCNSQEKECEGILTELETKGSYTFEAPDLDWSRGDSDEVVKRYKVAIEIKGALSSNELEILPPQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF48</accession>
    <name>KCY_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytidylate kinase</fullName>
            <shortName evidence="1">CK</shortName>
            <ecNumber evidence="1">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytidine monophosphate kinase</fullName>
            <shortName evidence="1">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmk</name>
        <name type="ordered locus">Swoo_2310</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324931.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KF48"/>
    <dbReference type="SMR" id="B1KF48"/>
    <dbReference type="STRING" id="392500.Swoo_2310"/>
    <dbReference type="EnsemblBacteria" id="ACA86589">
        <property type="protein sequence ID" value="ACA86589"/>
        <property type="gene ID" value="Swoo_2310"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2310"/>
    <dbReference type="eggNOG" id="COG0283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079959_2_0_6"/>
    <dbReference type="OMA" id="RAITWWM"/>
    <dbReference type="OrthoDB" id="776861at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000100687" description="Cytidylate kinase">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="12"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <sequence length="230" mass="24927" checksum="309BB83D3B473056" modified="2008-04-29" version="1">MSERAPVVTIDGPSGAGKGTISQLLAERLGWKLLDSGAIYRVLALAAIHHNVELDNEDSLTLLAAHLDVQFITGNGSKGIKVVLEGEDVSNDIRSQECSNAASKVAAFPRVREALLRRQRAFSEAPGLIADGRDMGTVVFSKAPVKLYLTASAEERAQRRYNQLQDKGFDVNIDQLLTEIKERDDRDMNRSVAPLVPAEDALVIDTSQIGIEEVLNIALAHIETNLSGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF93</accession>
    <name>B1KF93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324976.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2355"/>
    <dbReference type="EnsemblBacteria" id="ACA86634">
        <property type="protein sequence ID" value="ACA86634"/>
        <property type="gene ID" value="Swoo_2355"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2355"/>
    <dbReference type="eggNOG" id="ENOG5033QCD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091612_0_0_6"/>
    <dbReference type="OrthoDB" id="1411229at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22562" checksum="D7E5E3313B13886F" modified="2008-04-29" version="1">MTTHIKFINNSTNKNLPSIIITAENNISTFNMVTDGIAWRVLKNIGRGSQSSFKYNANYSIRAGWDNGENVTSLLAAQLGKKYQVTSNNTGIILQNIGNTNSTEEIELINNIKVNDGVLAQLFNDNKIIMGKKSVGYGQSAVFKPSNKLYWGIASEIDEGKGLSSKSAVLNSNSFFELDLDGISDALVSLNGNAKDGFFFQTEYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFF6</accession>
    <name>B1KFF6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3873</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326461.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3873"/>
    <dbReference type="EnsemblBacteria" id="ACA88131">
        <property type="protein sequence ID" value="ACA88131"/>
        <property type="gene ID" value="Swoo_3873"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3873"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_1_2_6"/>
    <dbReference type="OMA" id="LMHPDFG"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="8"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="103"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="27609" checksum="8BF94A594466C3E7" modified="2008-04-29" version="1">MEHNPTQMRLAKYLAQTGLCSRRAATRYIRDGLITIEGRIANHIDTVTLIETPQGIESSEQLTFDGAPISAVEEKEYWAFHKAVGTDSRLLIDDSSSLLHLLPATPRLYPVGRLDKDSRGLLLLTNDGELTQTLMHPDFGHSKIYHVRVDRDFDDNFLQAMAQGVSYRDVTTLPCTLTRLAKDQFEITLTQGLNRQIRRMSQALGFKVIDLKRVKIQSLALGDLKEGEMRQLTSSELINLKSALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFR9</accession>
    <name>B1KFR9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0942</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323582.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0942"/>
    <dbReference type="EnsemblBacteria" id="ACA85235">
        <property type="protein sequence ID" value="ACA85235"/>
        <property type="gene ID" value="Swoo_0942"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0942"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_8_1_6"/>
    <dbReference type="OMA" id="KTMAIGR"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="23"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="202" mass="22644" checksum="265A47D6CFEB0CEE" modified="2008-04-29" version="1">MSDDATQANSSNKEEHHHFKIFKPYGFLSQFVPETRKRKKLLAELADFPKGTMAIGRLDHDSEGLLLLTTDGMVSHQVRSKKVEKEYYVQLDGDITADAITQLQNGVEIGIKGDKYLTLPCRVFKLASEPNLPANGRKVRDLRHGPMSWISITISEGKNRQIRKMTAAAGFPTLRLVRVRIGNIDINEMQAGDVLPLSFPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS3</accession>
    <name>B1KFS3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0946</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323586.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0946"/>
    <dbReference type="EnsemblBacteria" id="ACA85239">
        <property type="protein sequence ID" value="ACA85239"/>
        <property type="gene ID" value="Swoo_0946"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0946"/>
    <dbReference type="eggNOG" id="COG4773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_9_0_6"/>
    <dbReference type="OMA" id="VETEYHY"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764830" evidence="7">
        <location>
            <begin position="27"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="61"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="275"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="706" mass="78367" checksum="656EDF422CCE1D61" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS6</accession>
    <name>B1KFS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase U32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323589.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0949"/>
    <dbReference type="MEROPS" id="U32.003"/>
    <dbReference type="EnsemblBacteria" id="ACA85242">
        <property type="protein sequence ID" value="ACA85242"/>
        <property type="gene ID" value="Swoo_0949"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0949"/>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011540_5_0_6"/>
    <dbReference type="OMA" id="MKDNNQS"/>
    <dbReference type="OrthoDB" id="1264653at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020988">
        <property type="entry name" value="Pept_U32_collagenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12392">
        <property type="entry name" value="DUF3656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01276">
        <property type="entry name" value="PEPTIDASE_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3656" evidence="1">
        <location>
            <begin position="402"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="641" mass="71430" checksum="C0315A023DB5DFA4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG07</accession>
    <name>B1KG07_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325056.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2436"/>
    <dbReference type="EnsemblBacteria" id="ACA86714">
        <property type="protein sequence ID" value="ACA86714"/>
        <property type="gene ID" value="Swoo_2436"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2436"/>
    <dbReference type="eggNOG" id="COG3055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050826_0_0_6"/>
    <dbReference type="OMA" id="NIARCRH"/>
    <dbReference type="OrthoDB" id="1977684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="SSF50965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767034" evidence="2">
        <location>
            <begin position="32"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="377" mass="40841" checksum="CE094A7D022D3025" modified="2008-04-29" version="1" precursor="true">MKYSIKPMQLMTLVSCLMLFTLIVRQGCAIAAENMQQGKVQTIQMSVERAAHQATGLKNGKVFVSGGCAQRGCEGIHRSTELFDSSHRKFSPAGDMLEPRVSHASILLNDGRVLIVGGWTGKGISRSAEIYDVKTNAFTAIEDMSVARIGPVVTPLKDGQILITGGEPRPGFGLNSSELFDPVRLTFSLSGKMNANRGAHVAVALVDGRVLVTGGHSARGDILRSAEIYDPDTGKFTPTGEMTIPRHKHGGILLADGRVLIVGGSNKQDFRGRYTSSELYDPDTGKFTSGPTMHWPRFKIRHSLVLLPSGAVLVAGGAVKNERFEPDSFKFVETGDELSKPLMFNSTSLLPSGEVLAVGGYDERIQPLKETWLIEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG08</accession>
    <name>B1KG08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325057.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2437"/>
    <dbReference type="EnsemblBacteria" id="ACA86715">
        <property type="protein sequence ID" value="ACA86715"/>
        <property type="gene ID" value="Swoo_2437"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2437"/>
    <dbReference type="eggNOG" id="COG3279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_939395_0_0_6"/>
    <dbReference type="OMA" id="MIHTIFR"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="2">
        <location>
            <begin position="164"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="273" mass="31346" checksum="A00F22169114D0D5" modified="2008-04-29" version="1" precursor="true">MNKLTLIFKPSLGNKLLGFFLLVLIAIVTLATFQDYLHSKRGGYPFFFSESLLFKTLWFLFPPILLLIKSVFQQRRITTPFQMGLVVLVATLVHLLLVPLIIWCLSTIFREQSYGFVKVLTFTLSNDLVKIVLVYGVYLFLLNYLGAKNKKTQLKKHKIPSQYLSVSNGKNNTRIKLSDISYIKAATPYIAIQVENKQHLHSETLKSIGGKLDPRFVRVHKSSIVNIEHVLSYKSRLNGDYDLLLEDGAEIRLSRNYVNDFKKCFEPTPQLTQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG60</accession>
    <name>IF3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">infC</name>
        <name type="ordered locus">Swoo_2490</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG60"/>
    <dbReference type="SMR" id="B1KG60"/>
    <dbReference type="STRING" id="392500.Swoo_2490"/>
    <dbReference type="EnsemblBacteria" id="ACA86767">
        <property type="protein sequence ID" value="ACA86767"/>
        <property type="gene ID" value="Swoo_2490"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2490"/>
    <dbReference type="eggNOG" id="COG0290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054919_3_2_6"/>
    <dbReference type="OMA" id="RNMIMFL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0396">Initiation factor</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000202547" description="Translation initiation factor IF-3">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <sequence length="180" mass="20362" checksum="B65F1B31D66B1E12" modified="2008-04-29" version="1">MKIKKTAGRQAAPNRINELITGISEVRLNGLDGEPLGLMTIREAQELADEAGVDLVEISPNAEPPVCRIMDYGKFLFDKAKSQKEQKKKQKIVQVKEIKFRPGTDENDYQVKLRNLNRFLDDGDKAKVTLRFRGREMAHQSLGMNLLNRIKDDLAEIAVVESFPKMEGRQAVMVLAPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG66</accession>
    <name>B1KG66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326533.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88203">
        <property type="protein sequence ID" value="ACA88203"/>
        <property type="gene ID" value="Swoo_3946"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3946"/>
    <dbReference type="eggNOG" id="ENOG5031E5S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1926138_0_0_6"/>
    <dbReference type="OMA" id="LKADWYG"/>
    <dbReference type="OrthoDB" id="1856809at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15089" checksum="C5FE607E1F33D9FE" modified="2008-04-29" version="1">MQEDLPITIAADGQFSSALKPLLMKLEMWINFQALKADWYGNEDFILSFDFTLVRSLDEKVQQITATGADSNESAESWVVKQGYAYHYQSSHLMTIAFIAVDDLLEDGVGIEQAIKDRMTSVANVVASQHGLLALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGA0</accession>
    <name>B1KGA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MltA-interacting MipA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MipA/OmpV family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326567.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3980"/>
    <dbReference type="EnsemblBacteria" id="ACA88237">
        <property type="protein sequence ID" value="ACA88237"/>
        <property type="gene ID" value="Swoo_3980"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3980"/>
    <dbReference type="eggNOG" id="COG3713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_986412_0_0_6"/>
    <dbReference type="OMA" id="KSWQVRN"/>
    <dbReference type="OrthoDB" id="1497770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010583">
        <property type="entry name" value="MipA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38776">
        <property type="entry name" value="PTHR38776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06629">
        <property type="entry name" value="MipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766572" evidence="5">
        <location>
            <begin position="29"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="33088" checksum="AA3CC3FD56D2780A" modified="2008-04-29" version="1" precursor="true">MNNLSHRWPFILTMLLLILAFAPQVSRASDIANSVTGREDNRLVNGGYFELGASVYGVNKIDVRQTDHQTIQPSLLLSGMYQYKGLFVEMLHQSQDGINLGYNFWNSENWSLDLLVANLQSSWARPEGIDPKMLNEAERDLYLMSEDSIYVGAGFRATRYWDDHYVFQYRIVSDYYDDQGLQSSARLGKSWQVRNWNFHALASVEYASATLNNHLFGVSSDEATTRFPEYHPDSSFHYGMEFGVAYPLSESLVFRAMYRFNVLSDEVTDSPFNQAGHVSFFNASISYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGI9</accession>
    <name>B1KGI9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secretion protein HlyD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323664.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1024"/>
    <dbReference type="EnsemblBacteria" id="ACA85317">
        <property type="protein sequence ID" value="ACA85317"/>
        <property type="gene ID" value="Swoo_1024"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1024"/>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_15_3_6"/>
    <dbReference type="OMA" id="AWAIFKI"/>
    <dbReference type="OrthoDB" id="757027at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="64"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="378" mass="41864" checksum="2A865E6AD0EC9B3E" modified="2008-04-29" version="1">MDLLLILTYTAICIAIFKIFKIPLTKWTVPTAILGGVFIVGALILLMNYNHPYTPFAKEYFVSTPINPAVRGVVTSVEVEPNVPVKKGDVLFRLDPTPFEAIVKQKRAALVSAEQEVPQLEAAWQSALANVERAEADRDRTKSAYDRYAKGKKRGGANSPFTELELDNKRQLYLASEAQLTVAQAEELRVRLAFESNVDGVNTKVAGIQGQLEKALFDLEMTVVRAPADGMVTQMALRPGIVAVPMPLRSLMSFIPDEDRYFAGAFWQNSLLRLKEGDEAEVILDGAPGEVFIGKVAKILPAMAEGEIQSSGALISSRNLMQRGRVIVLIEIDHHEIRDKFPAGVSGQAAIYTDHFSHVAVMRKVLLRMQGWLNYLFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV7</accession>
    <name>B1KGV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325167.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2549"/>
    <dbReference type="EnsemblBacteria" id="ACA86826">
        <property type="protein sequence ID" value="ACA86826"/>
        <property type="gene ID" value="Swoo_2549"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2549"/>
    <dbReference type="eggNOG" id="ENOG5033CMH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126580_0_0_6"/>
    <dbReference type="OMA" id="HNLSGHE"/>
    <dbReference type="OrthoDB" id="2013618at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021879">
        <property type="entry name" value="Ribosomal_S4Pg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11993">
        <property type="entry name" value="Ribosomal_S4Pg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="18294" checksum="0512909C0350544E" modified="2008-04-29" version="1">MRPSAVLINESQLGTRLNHAIDHDRRGEFALLLALLSCDARDMAQFQLDDGALEPELALRKKFELPEAQALINDLTIQDSPIDNSSAFSHGGVRAFQLMQALKPEALVIRGDKSAQMQRVLTNCDLLTRQKFNHSAKSELYHALDTHFVDQLAQQRQMSRTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGZ1</accession>
    <name>B1KGZ1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326632.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4047"/>
    <dbReference type="EnsemblBacteria" id="ACA88303">
        <property type="protein sequence ID" value="ACA88303"/>
        <property type="gene ID" value="Swoo_4047"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4047"/>
    <dbReference type="eggNOG" id="COG5470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145407_4_0_6"/>
    <dbReference type="OMA" id="KWVPAYA"/>
    <dbReference type="OrthoDB" id="1534521at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010753">
        <property type="entry name" value="DUF1330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07045">
        <property type="entry name" value="DUF1330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1330" evidence="1">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="108" mass="11955" checksum="504DC075804121CD" modified="2008-04-29" version="1">MTVYVIADIKITEDIWVPEYAASVHEIVHRHGGKYLSRSGNVKTLEGKPLETTLIALLAFPTEASVQAFLSDPEYAPYRRARVSGSESRFQLIDDTDLAGTIPYLSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH25</accession>
    <name>B1KH25_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Cobyric acid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cobQ</name>
        <name evidence="10" type="ordered locus">Swoo_4081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326666.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4081"/>
    <dbReference type="EnsemblBacteria" id="ACA88337">
        <property type="protein sequence ID" value="ACA88337"/>
        <property type="gene ID" value="Swoo_4081"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4081"/>
    <dbReference type="eggNOG" id="COG1492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019250_2_2_6"/>
    <dbReference type="OMA" id="EIHHGVA"/>
    <dbReference type="OrthoDB" id="744477at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01750">
        <property type="entry name" value="GATase1_CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00028">
        <property type="entry name" value="CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033949">
        <property type="entry name" value="CobQ_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004459">
        <property type="entry name" value="CobQ_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF1">
        <property type="entry name" value="PTHR21343:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00313">
        <property type="entry name" value="cobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="8">
        <location>
            <begin position="18"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="9">
        <location>
            <begin position="276"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="527" mass="57235" checksum="5929DFADD6D89D30" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH34</accession>
    <name>B1KH34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4090"/>
    <dbReference type="EnsemblBacteria" id="ACA88346">
        <property type="protein sequence ID" value="ACA88346"/>
        <property type="gene ID" value="Swoo_4090"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4090"/>
    <dbReference type="eggNOG" id="ENOG502ZCEN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430141_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="636" mass="71972" checksum="A7C94EC9593F5F19" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH48</accession>
    <name>B1KH48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Choline/carnitine/betaine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326689.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88360">
        <property type="protein sequence ID" value="ACA88360"/>
        <property type="gene ID" value="Swoo_4104"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4104"/>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010118_6_0_6"/>
    <dbReference type="OMA" id="RWNRLFW"/>
    <dbReference type="OrthoDB" id="1217683at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018093">
        <property type="entry name" value="BCCT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00842">
        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01303">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="601"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="620"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="650" mass="71501" checksum="341EAD19A0B62E58" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH55</accession>
    <name>B1KH55_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Periplasmic nitrate reductase, electron transfer subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Diheme cytochrome c NapB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_4111</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 2 heme C groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the NapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326696.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4111"/>
    <dbReference type="EnsemblBacteria" id="ACA88367">
        <property type="protein sequence ID" value="ACA88367"/>
        <property type="gene ID" value="Swoo_4111"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4111"/>
    <dbReference type="eggNOG" id="COG3043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103367_1_0_6"/>
    <dbReference type="OMA" id="CLTCHSW"/>
    <dbReference type="OrthoDB" id="1650975at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009061">
        <property type="term" value="P:anaerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005591">
        <property type="entry name" value="NapB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38604">
        <property type="entry name" value="PTHR38604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03892">
        <property type="entry name" value="NapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006105">
        <property type="entry name" value="NapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0574">Periplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766599" description="Periplasmic nitrate reductase, electron transfer subunit" evidence="13">
        <location>
            <begin position="19"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA88367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15783" checksum="66A017E2C5E246EE" modified="2008-04-29" version="1" precursor="true">MKKLFTAAALIMALGACSGQQTNTQADPVNINSLGKSEITEVRAADAMPLYPKRGKSIERDFVHQPPMIPHKADYKITMKKNGCMSCHSWDKAEKRKATPIDISHVKDEKGSLNNQYYSCSQCHAPMAENKQPLVENTFSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH71</accession>
    <name>B1KH71_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase C39 bacteriocin processing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326712.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4127"/>
    <dbReference type="EnsemblBacteria" id="ACA88383">
        <property type="protein sequence ID" value="ACA88383"/>
        <property type="gene ID" value="Swoo_4127"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4127"/>
    <dbReference type="eggNOG" id="COG3271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092029_0_1_6"/>
    <dbReference type="OMA" id="YWLDVDE"/>
    <dbReference type="OrthoDB" id="1287580at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C39" evidence="1">
        <location>
            <begin position="59"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="235" mass="26735" checksum="61CCD34E0BD97CEB" modified="2008-04-29" version="1" precursor="true">MNIFLQYTLIVVLVSLLSIPIFSLVAAEMVLDGLVKGMGSYSKEIQSIRERRFEYVIEQKTDFSCGAASLASILKYAYGNDEITEQSVLLGMLESADIDVVKQQGFSLLDMKRYLTAREFRGRGYNISDEELLLLKIPAIVLLNDSGYHHFVVLRRVEDGLVYLGDPALGNRIMALDEFVQKWNRVVFVVIGKEYDKQNKLLQPRARLTYRALSTHKPLTDAELMEFGFAYSDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHC2</accession>
    <name>B1KHC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323776.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1137"/>
    <dbReference type="EnsemblBacteria" id="ACA85430">
        <property type="protein sequence ID" value="ACA85430"/>
        <property type="gene ID" value="Swoo_1137"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1137"/>
    <dbReference type="eggNOG" id="COG0674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017038_1_0_6"/>
    <dbReference type="OMA" id="GMPTRTQ"/>
    <dbReference type="OrthoDB" id="360732at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="19"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="3">
        <location>
            <begin position="221"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="609" mass="66924" checksum="B8FD2E1AA8613F0A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHK9</accession>
    <name>B1KHK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_2617</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325234.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2617"/>
    <dbReference type="EnsemblBacteria" id="ACA86894">
        <property type="protein sequence ID" value="ACA86894"/>
        <property type="gene ID" value="Swoo_2617"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2617"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_21_6"/>
    <dbReference type="OMA" id="DRVQKYA"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033480">
        <property type="entry name" value="sCache_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17200">
        <property type="entry name" value="sCache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01049">
        <property type="entry name" value="Cache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="217"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="276"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="548" mass="59426" checksum="4C135F6DCB1FB574" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHN9</accession>
    <name>B1KHN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325264.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2647"/>
    <dbReference type="EnsemblBacteria" id="ACA86924">
        <property type="protein sequence ID" value="ACA86924"/>
        <property type="gene ID" value="Swoo_2647"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2647"/>
    <dbReference type="eggNOG" id="ENOG5032Y10">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150033_0_0_6"/>
    <dbReference type="OMA" id="NDYEDVW"/>
    <dbReference type="OrthoDB" id="1749906at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="12681" checksum="B6E845FA35C75D22" modified="2008-04-29" version="1">MVSQKEVCEKFKADFIPCSDVEKLGLAIETIGKLPINGLRHKAENGTCGWYIWCGEELSQETDFFKPLHVSHIKEYLPEIEQYLALPPGYRFLIADDYEDVWHDSSLTNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP4</accession>
    <name>B1KHP4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325269.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86929">
        <property type="protein sequence ID" value="ACA86929"/>
        <property type="gene ID" value="Swoo_2653"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2653"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="ENAWVET"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="37576" checksum="334DCAD0624BBFB4" modified="2008-04-29" version="1">MPRPRRSQISLEDTPMYHCCSRVTRRAFLFGDDALTGKNYDHRRDWVESQLLKLAAVFAIDIAAYAVMSNHLHLVLRVDIYEANAWSDREVVEHWHNLFKGTDITQKFAKGEVIESFEVNSLKHSIAQYRSRLCDISWFMRCLNEPIARMANKEDKCTGRFWEGRFKSQALLDDAAILACMAYVDLNPIRAKMATTPERSNFTSIQRRIEAALDGEQPTSLLPFVGNERKEMPKGLMFSAKDYLQLVDDTGRIIREDKRGAISQASQRILDRLNIPQENWLKLTTDFGDLFKGAVGTLQELDVFCEHQEKKRRQGAANCHRWLDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS3</accession>
    <name>B1KHS3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326730.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4145"/>
    <dbReference type="EnsemblBacteria" id="ACA88401">
        <property type="protein sequence ID" value="ACA88401"/>
        <property type="gene ID" value="Swoo_4145"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4145"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="PKTMKSH"/>
    <dbReference type="OrthoDB" id="38744at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="863"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="889"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="915"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="957"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="991"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1021" mass="113375" checksum="45C02D74F53FCFC2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHW1</accession>
    <name>B1KHW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326768.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4183"/>
    <dbReference type="EnsemblBacteria" id="ACA88439">
        <property type="protein sequence ID" value="ACA88439"/>
        <property type="gene ID" value="Swoo_4183"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4183"/>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030006_3_2_6"/>
    <dbReference type="OMA" id="CYTVNNP"/>
    <dbReference type="OrthoDB" id="1542724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="235" mass="26407" checksum="CC9ABCBFB987C1D6" modified="2008-04-29" version="1">MIIFAHRGASGYAPENTLAAMKKAIELGCRAIELDIHSVEGELYVFHDRRLDHKSDGKGVIDQVSQQYLNTVSVQNEPIPTLWEVMAFLSKYDCIVNIELKGMTCLTPFISLYPRLLNELNFTPDQLLISSFHHGFLQQFRQSYSDAYIAPLIEGVQLDNTHTASLLNAYSIHLSLSFINQALIDEAHAKGLKVFVYTVDHIDDVKMLSNMGIDGIFSNYPDRASKILEESGIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI05</accession>
    <name>B1KI05_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323829.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1190"/>
    <dbReference type="EnsemblBacteria" id="ACA85483">
        <property type="protein sequence ID" value="ACA85483"/>
        <property type="gene ID" value="Swoo_1190"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1190"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066193_1_0_6"/>
    <dbReference type="OMA" id="WVIQRFR"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="159"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="271" mass="31014" checksum="0C61F37D31A144F6" modified="2008-04-29" version="1">MNYQTFQPHPDLESLISCYWTLEVPSTGDTQRQTIVPDGTIEMAFILGDDIKRYTSESHFIIQPRAMVLGQNTTSFNIEPTGYVDTFAVRFYPYGFANFVNVPIKTLANKETPIEMLFEKTVAQDLEQEIIQASDTKQRIEIIELFLLKKLTEHTMADRIVRTTIDTLLTTKGGTSISEIFKDDPSKRRQLERMFVNKVGVSPKQLGKLIRLQSALKMLLNEEGGTLTNIAYENDYYDQSHFTKDFKDFTGVSPKEFLGNENMALSSIFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KID7</accession>
    <name>B1KID7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2712"/>
    <dbReference type="EnsemblBacteria" id="ACA86988">
        <property type="protein sequence ID" value="ACA86988"/>
        <property type="gene ID" value="Swoo_2712"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2712"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_18_6_6"/>
    <dbReference type="OMA" id="MCLWEEE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="17190" checksum="8823511B59A65442" modified="2008-04-29" version="1">MWRCCLKQSESLGYLVSHLNVDLQNALDQKLKRYQLDIKLWPVLFALWQEEGITQTELSKRCDVANYTMTRILDQLQTQGLVTRHQEADNRRAFQILLTDSGKALEQDLIVEAERVNEHFLENLSMDERLAFVSLLNKINRFPPDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII8</accession>
    <name>B1KII8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BolA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326811.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4228"/>
    <dbReference type="EnsemblBacteria" id="ACA88484">
        <property type="protein sequence ID" value="ACA88484"/>
        <property type="gene ID" value="Swoo_4228"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4228"/>
    <dbReference type="eggNOG" id="COG5007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109462_4_1_6"/>
    <dbReference type="OMA" id="QIYAHLN"/>
    <dbReference type="OrthoDB" id="2009812at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="10820" checksum="0DABC3FC623F3A49" modified="2008-04-29" version="1">MNANETEQVNDDAAKLKELEQLLLDALSLDEVHVTQAGTHYKIVAVGECFEGMGRVKQQQTIYGPLMDRITSGELHALTINAFTPTQWKREKVFNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU4</accession>
    <name>B1KIU4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323938.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1300"/>
    <dbReference type="EnsemblBacteria" id="ACA85592">
        <property type="protein sequence ID" value="ACA85592"/>
        <property type="gene ID" value="Swoo_1300"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1300"/>
    <dbReference type="eggNOG" id="ENOG5031GYZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176325_0_0_6"/>
    <dbReference type="OMA" id="MQDYKCH"/>
    <dbReference type="OrthoDB" id="2006616at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767378" evidence="1">
        <location>
            <begin position="20"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="11178" checksum="9468D8B3197D95DC" modified="2008-04-29" version="1" precursor="true">MKRFMISIFLFSLSATTVASEKQDYKCFVNSTDGDKVVFYRWKTDELKLKMAKLVGRTNTNKRGKKYFIKTVQECVHTNENFESADAKKVDKVTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ05</accession>
    <name>B1KJ05_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YbaK/prolyl-tRNA synthetase associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323999.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1361"/>
    <dbReference type="EnsemblBacteria" id="ACA85653">
        <property type="protein sequence ID" value="ACA85653"/>
        <property type="gene ID" value="Swoo_1361"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1361"/>
    <dbReference type="eggNOG" id="COG2606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094875_2_1_6"/>
    <dbReference type="OMA" id="CEPGAMP"/>
    <dbReference type="OrthoDB" id="1503081at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="1">
        <location>
            <begin position="23"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="159" mass="17962" checksum="DC3904B4F54F0308" modified="2008-04-29" version="1">MTISVRLNEYLNQNEVSYDLISHPHSSSSISSAVAANIPPAQIAKAVILEDHEGRKMMAVLLADHKISLGSLGEKLNRDLHLIDEKSVYKMFEDCEKGAIPPFGNAYNMEAVYDDLLVQSKELYLEAGDHNSLLRVSREDFVRLIKDSKHMRFSHQTIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ45</accession>
    <name>B1KJ45_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325401.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87065">
        <property type="protein sequence ID" value="ACA87065"/>
        <property type="gene ID" value="Swoo_2789"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2789"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043381_0_0_6"/>
    <dbReference type="OMA" id="MYSLSHV"/>
    <dbReference type="OrthoDB" id="1694750at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="125"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="488" mass="55071" checksum="907ACA72EAFC14D5" modified="2008-04-29" version="1" precursor="true">MKTLVIGSTKHLLMALFYASLGVVIALLCGSIWYLTSRADLDVWHKTELKSAYKRSLEFDNFSQLMALEQVIFDEVEERIYGRTPHSFDSVINRYVRGSLSDPQKWRTDWNRSYEWPQADADFGVLLLHGMSDSPYATSHLAKHFKGKAHVLALRLPGHGTIPSGLIDIEWQDIASAVSLATEHMQKVLKGKPLYLVGFSTGAALGLNHELERLMKGQSTDYSGMIFLSPAIGLSPVAAGAKWQAWLGELLGLEKLSWNSLQTEYDPFKYNSFAVNAGDVVYQLAMRNQWLLSQLSSEALLSLETSLTFQSLVDDTVSTGAVVTDFYQKLPENGHELVIFDINRTEVNMGLILNDPLDYFEHLIERLPLHFKYTLVENRSGQGALRRQVQARTRYPNGDSNINLIAQEWPANVYSLSHVAIPFPIEDSLYGPEGVNYIDRVQIGATSSRGERGVLGVQADEMLRQKWNPFFPYLLDKMDRFIDKQNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD4</accession>
    <name>B1KJD4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone family protein DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4353</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326932.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4353"/>
    <dbReference type="EnsemblBacteria" id="ACA88606">
        <property type="protein sequence ID" value="ACA88606"/>
        <property type="gene ID" value="Swoo_4353"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4353"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_1_6"/>
    <dbReference type="OMA" id="PAFKISK"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="90" mass="9668" checksum="707E4326867C1E34" modified="2008-04-29" version="1">MNKTELVAKMAEHAELTKAEAARALKSFEETVTEAMKNGDKISIVGFGSFETSSRAARTGRNPQTGKEIQIPAATVPKFKAGKTLKDSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJH1</accession>
    <name>B1KJH1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4391"/>
    <dbReference type="EnsemblBacteria" id="ACA88643">
        <property type="protein sequence ID" value="ACA88643"/>
        <property type="gene ID" value="Swoo_4391"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4391"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_10_1_6"/>
    <dbReference type="OMA" id="HIPSHFE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="384" mass="42096" checksum="9B844A2DC260D9C3" modified="2008-04-29" version="1">MKPVQTMTFWQLVLSELKAIVSDKAIAVTLFGGVLFYSVLYPLPYLHQVPTEQQLVVVDLDHSSLSRRLIRHADASPKISVIGQVGSITEAKTWIESGRAHGLLVIPEGFRRDLLLGKGVTLSYGGDASYFLIYSAVAEGLVTAGMDAGKQVQLLGMLAKGEAPEQAAQSLNSVKVNSVPAFNPSLGYTPYVVPGLFLLILHQTLLIGTGILGAGQWKARGYWSELSPLQLISGRISAFMLIYLFFSSFYVGFCFYWYQVSIQASLGLVALFLLPFLLATSVAGIALSCLFVRRDLPTQVLLLASMPIMFVSGFVWPLALIPEPLIWISQAIPAVPAIMGMLELNQMGASWSSIMPKWLQLWGLFAVFFLLALYGVSRRLKESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT3</accession>
    <name>B1KJT3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325456.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2845"/>
    <dbReference type="EnsemblBacteria" id="ACA87120">
        <property type="protein sequence ID" value="ACA87120"/>
        <property type="gene ID" value="Swoo_2845"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2845"/>
    <dbReference type="eggNOG" id="ENOG5031QK4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115420_0_0_6"/>
    <dbReference type="OMA" id="FIARGWC"/>
    <dbReference type="OrthoDB" id="1674095at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021318">
        <property type="entry name" value="DUF2919"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11143">
        <property type="entry name" value="DUF2919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="155" mass="18110" checksum="3D0D8911EB6EDE6C" modified="2008-04-29" version="1">MNFSNITWLDDNGHIKPPIYLYFILIFLARGWCIFIASLTQASDRAALVALFYPQKADFMMALAAGAGALLLYGFIIAERKRSPVWVRPLFNQFRWVLLLLLLVDGGLLIERSINSHYLYSWSMGLDGLILFWSFIYLFKSKRLSHYFSDWKREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW7</accession>
    <name>B1KJW7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325490.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2879"/>
    <dbReference type="EnsemblBacteria" id="ACA87154">
        <property type="protein sequence ID" value="ACA87154"/>
        <property type="gene ID" value="Swoo_2879"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2879"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_6"/>
    <dbReference type="OMA" id="LYCLKER"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="34565" checksum="146B69E985797CA6" modified="2008-04-29" version="1">MKYSLKQITVFDAVASLESVSAAARKLSMTQSAVSMSLGQLENLLGRPLFIRQGNRLTLSHWGNWLRPKARRLLQDAQHIELGLHEQHLISGRFRLCSSQTAAEHLIPELISRIDTDFPELRIDLMVENTENVIDGLLNYEFDLGIIEGRNDDSRLHQERWIDDHLVVFSSPHHPYAKYESASLSQLEQAKWVLREQGAGTRRIFEGAIHGIIEKLNVWKEYEQVSVLKSLVKNGQYISSLPYLDVEKEVANGELVILPTPQLNMQRHLSFIWRADSGENPLRDCIITEARRLSRNRLLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK76</accession>
    <name>B1KK76_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4455"/>
    <dbReference type="EnsemblBacteria" id="ACA88707">
        <property type="protein sequence ID" value="ACA88707"/>
        <property type="gene ID" value="Swoo_4455"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4455"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136831_0_0_6"/>
    <dbReference type="OMA" id="PAHRYEH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767141" evidence="1">
        <location>
            <begin position="25"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="53"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="15761" checksum="49B3EFF7276BB279" modified="2008-04-29" version="1" precursor="true">MMKKALGQILVTLTLIASSASCLAGGGSEMAPAHRYEHQLNTISMMEAQTLVGKEGVYFFDVNTLELWAEGFIPGAVYFNVKDWKKLLPANKDAVMVFYCANRLCNASEIAAHAVMKLGYTGVRQMPDGIYGWRLANRPTEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK88</accession>
    <name>B1KK88_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Copper ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4468"/>
    <dbReference type="EnsemblBacteria" id="ACA88719">
        <property type="protein sequence ID" value="ACA88719"/>
        <property type="gene ID" value="Swoo_4468"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4468"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071765_1_0_6"/>
    <dbReference type="OMA" id="DSSRNRW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="286" mass="31651" checksum="380F452C3E85CB53" modified="2008-04-29" version="1" precursor="true">MQSSYRMNIYRPRSPIFIIAYKEICDSSRNRWLAFMGCMFLLLSLSVSFAGSAVTGSLYLPELDSLMSSLSTISVFIIPLAAILLCYDSFVGEEESGTLLLLLSYPLTRSQIIFGKLLGHITVMLVATGFAFGLTAALLLLVGEQYHSGELVMAFAQFLLSSNLLALTFILLSYIVSLKCTEKAKAIGCLLLLWFLFVLIYDLLLLTLLVSDFSFANQLLINVLIAMSPTDLYRAINLVAIEGEGANSLAMIVSTDWGLSAMYLLFLLWIVVLTFISHRIFKGKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK94</accession>
    <name>B1KK94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327051.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4474"/>
    <dbReference type="EnsemblBacteria" id="ACA88725">
        <property type="protein sequence ID" value="ACA88725"/>
        <property type="gene ID" value="Swoo_4474"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4474"/>
    <dbReference type="eggNOG" id="COG4235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036074_3_2_6"/>
    <dbReference type="OMA" id="AIDNWNI"/>
    <dbReference type="OrthoDB" id="1539126at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="26797" checksum="0D14AC03EF701823" modified="2008-04-29" version="1">MNTLLISISIILLLSLGWILCHHLMYGDDLAELEKEVGHFFGSNINIESKNVEKNNSYHLGVIGLFFICASVSLYLLIGSYQYLDSAKVDYNIDYLLVADINKGQKLAEENPGDPLVLLGLAQSYIDGGMYKDALGILEQLLTIDSENAQALGLKATSMYYRDDRVITMDTSLVIARALTLHHEELNTRLLIANDAYLKGNYQKAINNWNIVLTNKVQSFNRDAIYFAIDKSKKKLIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK95</accession>
    <name>B1KK95_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327052.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4475"/>
    <dbReference type="EnsemblBacteria" id="ACA88726">
        <property type="protein sequence ID" value="ACA88726"/>
        <property type="gene ID" value="Swoo_4475"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4475"/>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_0_2_6"/>
    <dbReference type="OMA" id="MGANPHK"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767142" description="Peptidyl-prolyl cis-trans isomerase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="152"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="267" mass="28586" checksum="61E17675E244ED6F" modified="2008-04-29" version="1" precursor="true">MKKLKKSVLAVVSCLTLSVSVSCFANSDLTTDVEKESYSIGASFGHHISSQVYGQSQLGAEVDMEQVVNGLLDALKDETKMSKEEVVTYLNQRAETLNAAKQVKLDALTAKNIAAGEAFMAENAKNSDVKQTESGLQYEVITMGKGAMPAGNDVVTVHYKGTLIDGTEFDSTYERNEPNRFSLITVIEGWQEALALMPQGSKFKLTIPPALAYGERVVGMIQPHSTLVFEVELVKVEEPGEGAHGMGLSGMGMGGMMGGSMGANPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKE6</accession>
    <name>B1KKE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1498"/>
    <dbReference type="EnsemblBacteria" id="ACA85786">
        <property type="protein sequence ID" value="ACA85786"/>
        <property type="gene ID" value="Swoo_1498"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1498"/>
    <dbReference type="eggNOG" id="COG0701">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059148_1_0_6"/>
    <dbReference type="OMA" id="MIYGFMP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="307" mass="32960" checksum="26F5F263EE399E2D" modified="2008-04-29" version="1">MLSQSTINMLQETLNMFIFLAVELTLLFLAISYLVGVLQEYIPPSKIQNILSSKNGKGYLVAGFLGAITPFCSCSTIPFLKGLLRAKAGFGTMMVFLFASPLLNPIIIGLFAVTFGLKVTLFYFVMAMGVSVIAGYALERLGFEKYIKAEAYEEPKPSCCGTSCGAKPAAISKWRRIWNTTWKDFKKVLPYLIGGIAVGSMIYGFMPTEFVAKVASDSNPFAVPIAAIIGIPLYIRAEAVIPLSAALAAKGMGLGAVMALIIGSAGASLTEVILLKSLFKNQLIIAFLTVIITMAIGAGYLYGFIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL3</accession>
    <name>B1KKL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325566.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87230">
        <property type="protein sequence ID" value="ACA87230"/>
        <property type="gene ID" value="Swoo_2957"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2957"/>
    <dbReference type="eggNOG" id="ENOG502ZP93">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160027_0_0_6"/>
    <dbReference type="OMA" id="ETIPHEM"/>
    <dbReference type="OrthoDB" id="1693532at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="106" mass="11956" checksum="438FA4C1952F71FF" modified="2008-04-29" version="1">MNDEQYFLDGKFMLKSVPHEIKMSHWIDAPVLIDTKSNNTVLDLTGGVWDLKSVFSSTDSITIILARYPNRENDLELILFPLKGVATINGKSISITDIREFLAKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN3</accession>
    <name>B1KKN3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_2979</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325586.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2979"/>
    <dbReference type="EnsemblBacteria" id="ACA87250">
        <property type="protein sequence ID" value="ACA87250"/>
        <property type="gene ID" value="Swoo_2979"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2979"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_142_0_6"/>
    <dbReference type="OMA" id="DVERCHE"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="464"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="537"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="607"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="847"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="993"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="14">
        <location>
            <begin position="1166"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="899"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1042"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="7">
        <location>
            <position position="1205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA87250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1340" mass="149598" checksum="14C58728C3ACFCF8" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW5</accession>
    <name>B1KKW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4520"/>
    <dbReference type="EnsemblBacteria" id="ACA88771">
        <property type="protein sequence ID" value="ACA88771"/>
        <property type="gene ID" value="Swoo_4520"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4520"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="HECLILH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="309" mass="34599" checksum="D1A0BF0E3A385CDB" modified="2008-04-29" version="1">MDLNRVQMFAQVVEQGSFTAAAKVMGLTKATVSRKVAELEADAGVQLLFRTTRALKLTDAGNAYYNRVHRILADLQSAEDQLSSNQQMVKGNLNIVCPIELGQLFLGRVFAQFLTHYPDITIDAELTNRNVDVVAEGVDVLFQITSMSDPSLQTYEMINTDKMLMASPSYLARNGTPKVPQDLSKHKAIKLKSTHIDGSWTLFDGKEWVTQEPEAQLTVNNVTLAREAAIEGLGITIVPTLIAQQALDEKLLLPLLEDYPLAQTKITMSTPQRAYLPRKYQVFIEYIYRAMSRNPEYQLLEVPDFVSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG6</accession>
    <name>B1KLG6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidoglycan hydrolase FlgJ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Muramidase FlgJ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1605</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the glycosyl hydrolase 73 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the FlgJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324237.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1605"/>
    <dbReference type="CAZy" id="GH73">
        <property type="family name" value="Glycoside Hydrolase Family 73"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85891">
        <property type="protein sequence ID" value="ACA85891"/>
        <property type="gene ID" value="Swoo_1605"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1605"/>
    <dbReference type="eggNOG" id="COG1705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3951">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013771_3_0_6"/>
    <dbReference type="OMA" id="EGVFVQM"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019301">
        <property type="entry name" value="Flagellar_prot_FlgJ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013377">
        <property type="entry name" value="FlaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10135">
        <property type="entry name" value="Rod-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00047">
        <property type="entry name" value="LYZ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02541">
        <property type="entry name" value="flagell_FlgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="10">
        <location>
            <begin position="167"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="336" mass="36780" checksum="515BEBABBD4E9045" modified="2008-04-29" version="1">MEKLSNSSHFLDLGGLDSLRAQAKKDDKAALKEVAQQFEGIFVQMLMKSMRDANAAFESDSPMNSQYTKFYEQMHDQQMSVNLSDKGMLGLADLMVQQLSPETSNVTPASVLRGNANLGEGVEQAMVMSRATRGGAITQHASQPALDTEAAMEPLKAVLSGKQLPSEATSSNMTFADRNDFIAKLYPHAKKAADSLGTQPEVLIAQSALETGWGQKMIKRQGGDSSNNLFNIKADNRWQGDKAAVKTLEFEQGVAVQQRADFRVYDGIKQSFDDFVSFISDGPRYQEAMKKAANPNEFIKALQDAGYATDPEYANKVIKVMKSLSSELQTVIPGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP2</accession>
    <name>B1KLP2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RraB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325675.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3068"/>
    <dbReference type="EnsemblBacteria" id="ACA87339">
        <property type="protein sequence ID" value="ACA87339"/>
        <property type="gene ID" value="Swoo_3068"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3068"/>
    <dbReference type="eggNOG" id="ENOG5033MBQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157098_0_0_6"/>
    <dbReference type="OMA" id="KWELIVC"/>
    <dbReference type="OrthoDB" id="1479816at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036701">
        <property type="entry name" value="RraB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009671">
        <property type="entry name" value="RraB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06877">
        <property type="entry name" value="RraB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89946">
        <property type="entry name" value="SSF89946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RraB" evidence="1">
        <location>
            <begin position="6"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14323" checksum="9D595087323F2A90" modified="2008-04-29" version="1">MQFPDDDNGKMLAAMSEAGIDLSKQLDVDFFLVFEDQRDAESATEELAGSDLEGEMELHLNDELGKWELIVCIKMVPEYQAIVDQELQLNGFAEEFGGATDGWGVMQHQEGDDEFADDDHECSDSCKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS9</accession>
    <name>B1KLS9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325712.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3105"/>
    <dbReference type="EnsemblBacteria" id="ACA87376">
        <property type="protein sequence ID" value="ACA87376"/>
        <property type="gene ID" value="Swoo_3105"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3105"/>
    <dbReference type="eggNOG" id="COG4172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_6"/>
    <dbReference type="OMA" id="PHGRVKA"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="37893" checksum="373D09D59C01303C" modified="2008-04-29" version="1">MPLLDIRNLTIELDTPHGRVKALERVSLTVNPAEVHGLVGESGSGRSLLARAILGIPGHNWSITADRMMWDGRNLLEMSPKQRRNLMGSEISMIFQDPSSSLDPVISIGDQLIEAMPSHKNIPFWRRGKKRKQTAEKWLHKVGIKNTDRVMSSYAWELSEGECQKVMIAMAVANQPRLLIADEPTNSMEVQTQAQIFRLLSKLNQLQGVSILLISHELETLSMWCDQLSVMYCGQVMESGPTSEIVERPFHPYTKTLLDNIPNYSGTMNHKSMMPTLPGSAPALQHLPIGCRLGPRCPEAQKKCVNKPNLCHKKNRYFACHFPYHEEQCNDDSTPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV9</accession>
    <name>B1KLV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327164.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4589"/>
    <dbReference type="EnsemblBacteria" id="ACA88839">
        <property type="protein sequence ID" value="ACA88839"/>
        <property type="gene ID" value="Swoo_4589"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4589"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1184398_0_0_6"/>
    <dbReference type="OMA" id="HAEAYTW"/>
    <dbReference type="OrthoDB" id="1702213at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767194" evidence="1">
        <location>
            <begin position="20"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="24167" checksum="DC531AD93F4D8C58" modified="2008-04-29" version="1" precursor="true">MKTSIIIASIALLPSLTHANEIPAIDTASNTMNVAALQNLSQQTQNYDRAYANYRLAITANILGQSETAINALTSAQATLENLDQADAENLALLASVYGMQIALDNSQSAHLGPKIGQMLAQAQLLDPTNPRVVLVQAISAFNTPISFGGSMKKAMELSSKAIALYEVPCDEICWGHAEAYTWRGLAKQSTGDSQGAIADWQAAIEVQADYGWANFLLKQNQIAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLY4</accession>
    <name>B1KLY4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4614"/>
    <dbReference type="EnsemblBacteria" id="ACA88864">
        <property type="protein sequence ID" value="ACA88864"/>
        <property type="gene ID" value="Swoo_4614"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4614"/>
    <dbReference type="eggNOG" id="COG1246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112070_0_1_6"/>
    <dbReference type="OMA" id="GHIVIQE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012660">
        <property type="entry name" value="YiiD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09500">
        <property type="entry name" value="YiiD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02447">
        <property type="entry name" value="yiiD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YiiD_C" evidence="1">
        <location>
            <begin position="17"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17505" checksum="1AC4715868518BCC" modified="2008-04-29" version="1">MSIESNTTNIEYEQQLAKLTDTWHKTIPVSEFMQIAPVAFDGESLAVSAPLAPNINLHKTMFAGSIYTLATLTGWGMVWLQQSLAKVEGDIVLAEGQIRYLAPIDVNPVAKTEWPDADLSALQRGKRVRIPLMVELWCGDKKCAIFEGRFISLPTSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM71</accession>
    <name>B1KM71_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0183</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322833.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0183"/>
    <dbReference type="EnsemblBacteria" id="ACA84484">
        <property type="protein sequence ID" value="ACA84484"/>
        <property type="gene ID" value="Swoo_0183"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0183"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047522_1_0_6"/>
    <dbReference type="OMA" id="RMFKKHR"/>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="250"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="336" mass="38855" checksum="03BCC9353C5051D2" modified="2008-04-29" version="1">MKFNTSFIRVCYLKPVFDGMQQIFGIGYRDLNIPQTLMQEPMALIPFTQVGHWLTELAELSQDPCYMVKLSEYLHFNRLEITGIDPLATPDVAMSIRRINYGVVSLHSGASYYVSQSAKIMKWCYKNPYVFKQQKSLDSLRVAITLLNAQRHFLGKDYRPIRVQLSGSAIGHEQVSELFGSPVVWNAAQTEIWFDIDEMVHSISPDQEFNAPVTMPRSLFEKYLNMPQPHDAPKVLFEMINYSRFYGLPKVKAVAKLFNISEQQLQRRLQYLGLSFSTISNYIISNQAIKYMLDGKEIDEIASLLGYANQQSFSRAFKRLRRCTPQQYLDRLNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM88</accession>
    <name>B1KM88_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Ribosomal RNA small subunit methyltransferase D</fullName>
            <ecNumber evidence="4 9">2.1.1.171</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:23548"/>
            <dbReference type="Rhea" id="RHEA-COMP:10211"/>
            <dbReference type="Rhea" id="RHEA-COMP:10212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.171"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the methyltransferase superfamily. RsmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.171" evidence="4 9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322850.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0200"/>
    <dbReference type="EnsemblBacteria" id="ACA84501">
        <property type="protein sequence ID" value="ACA84501"/>
        <property type="gene ID" value="Swoo_0200"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0200"/>
    <dbReference type="eggNOG" id="COG0742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075826_2_2_6"/>
    <dbReference type="OMA" id="FNWLMPY"/>
    <dbReference type="OrthoDB" id="1827334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052913">
        <property type="term" value="F:16S rRNA (guanine(966)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 9 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR004553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="21690" checksum="86FEA80120417C97" modified="2008-04-29" version="1">MAKNRPSSGQVRIIAGQWRSRRLPIQDLEGLRPTTDRVRETLFNWLAGDLVGARILDCFGGSGALCLESLSRYASYAKVFELQASAAQQLKENLNTLKCSSDVAEVIKGDTLALLTVAPTEAFDIVYIDPPFRKELAEKTITLLAQNSWLKENAQIYVETESELVHLNVPSDWVQLKEKKAGQVTYRLYQYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC5</accession>
    <name>B1KMC5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322887.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0237"/>
    <dbReference type="EnsemblBacteria" id="ACA84538">
        <property type="protein sequence ID" value="ACA84538"/>
        <property type="gene ID" value="Swoo_0237"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0237"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_1_6"/>
    <dbReference type="OMA" id="DICWTAS"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="36766" checksum="65274B72EBC93069" modified="2008-04-29" version="1">MHRLLSRLDYFTLKVFIGLVEYNNGSVVAQKLNTTQPKVSRALSCVREVFCDELFVRRQYGVKPNAIAENLYPFAKAIVSAYDEMAELTMALPLRTHLIIAAQEHLSAFLVESIMELCEQLGSEISVTIQPWSDNVQELLAQGKIDFAIAVNSESFENVESVKVGEAHYHFVAAKKGHPLFSEQLNLANLFKNKLVLINYSQVGLTKHWCEDYADERGLELKVSFKTSSLAMALAHVAKSNDVCWTASVFACLYFKSRNDIDYIDVTDFYENELFPEGKFKRYDYYLQYHKSLNNDFSKQLSDLLSRKMQLALDAYAKDGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN9</accession>
    <name>B1KMN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3146"/>
    <dbReference type="EnsemblBacteria" id="ACA87417">
        <property type="protein sequence ID" value="ACA87417"/>
        <property type="gene ID" value="Swoo_3146"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3146"/>
    <dbReference type="eggNOG" id="ENOG5032UGD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056319_1_0_6"/>
    <dbReference type="OMA" id="NTKFCQP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766865" evidence="1">
        <location>
            <begin position="21"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="320" mass="37820" checksum="6995289030726FEC" modified="2008-04-29" version="1" precursor="true">MIFLRFILCCSIFISTLSFADDEIEKSQERSSDAEISNPCFTQSEQDGVIDGAFDYLNTKFCQPAIWFDSFFVDERSQEDARAGTLVRWTNDFSYYQKEGAKYRTELNARFNLPGVNQKLKVIIDTQGEDDPFAFLKGPDDEGERDIGLRYDWYGKDRVSFNIKANLKPKLEARWRYTYPISHNTVTRLTQKVYQEKKVTGESTEFDIEHSFNEEFLLRWSAVAQYENRGNGWEFGSSLNLYHYISSQQAINYIASIYGVDTPYHYVENARVAVTYRQNFLREWLFFEITPEYNWRKELESERLDQIILTFRLEVMFQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP8</accession>
    <name>B1KMP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325762.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3155"/>
    <dbReference type="EnsemblBacteria" id="ACA87426">
        <property type="protein sequence ID" value="ACA87426"/>
        <property type="gene ID" value="Swoo_3155"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3155"/>
    <dbReference type="eggNOG" id="ENOG50335I6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1748389_0_0_6"/>
    <dbReference type="OMA" id="EFWAAGT"/>
    <dbReference type="OrthoDB" id="1782106at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="17211" checksum="ED51DBFC7C9809F6" modified="2008-04-29" version="1">MTLALLADVEVLDTGSSQVHSPKEKSFSALNSNPFIGSWQLLSGRYLDETGAWSDYQSLHLNAIKVISDSHFSFTTVKETSEQGVNKLEFWAAGTGRYEYNDSQYIEYPTLNSFGAKEGASFAFEYEVKGDKLHTKRVEAGKLKEVEVWRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMT4</accession>
    <name>B1KMT4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Copper-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3191</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325798.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3191"/>
    <dbReference type="EnsemblBacteria" id="ACA87462">
        <property type="protein sequence ID" value="ACA87462"/>
        <property type="gene ID" value="Swoo_3191"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3191"/>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_0_3_6"/>
    <dbReference type="OMA" id="ITFFGWM"/>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="724"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="7">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="760" mass="80152" checksum="4836285C9A3112F4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMY6</accession>
    <name>B1KMY6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Elongation factor G</fullName>
            <shortName evidence="8">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fusA</name>
        <name evidence="10" type="ordered locus">Swoo_4693</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327262.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4693"/>
    <dbReference type="EnsemblBacteria" id="ACA88943">
        <property type="protein sequence ID" value="ACA88943"/>
        <property type="gene ID" value="Swoo_4693"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4693"/>
    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_4_1_6"/>
    <dbReference type="OMA" id="AATTCHW"/>
    <dbReference type="OrthoDB" id="88967at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="8"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="88"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="142"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="698" mass="76993" checksum="CA909B1D47E227E4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN27</accession>
    <name>B1KN27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General secretion pathway protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4734</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial secretin family. GSP D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327301.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4734"/>
    <dbReference type="EnsemblBacteria" id="ACA88984">
        <property type="protein sequence ID" value="ACA88984"/>
        <property type="gene ID" value="Swoo_4734"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4734"/>
    <dbReference type="eggNOG" id="COG1450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006756_1_1_6"/>
    <dbReference type="OMA" id="YAVVEMD"/>
    <dbReference type="OrthoDB" id="881521at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013356">
        <property type="entry name" value="T2SS_GspD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02517">
        <property type="entry name" value="type_II_gspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767508" evidence="10">
        <location>
            <begin position="29"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="11">
        <location>
            <begin position="130"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="11">
        <location>
            <begin position="195"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="11">
        <location>
            <begin position="270"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="679"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="694"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="714" mass="77657" checksum="56817DA654F79A3E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNC2</accession>
    <name>B1KNC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory protein GntR HTH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0318</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322968.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0318"/>
    <dbReference type="EnsemblBacteria" id="ACA84619">
        <property type="protein sequence ID" value="ACA84619"/>
        <property type="gene ID" value="Swoo_0318"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0318"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_5_6"/>
    <dbReference type="OMA" id="EWPVGSR"/>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="250" mass="28336" checksum="08409690110CBABC" modified="2008-04-29" version="1">MAYSKINQPKISDVIMGQLEQMILEGSLQPGQKLPPERELALQFEVSRPSLREAIQKLEAKGLLMRRQGGGTYVKEQLWQSLADPIVELMHSDSESQYDLLEFRHATEGMMAYFAALRGTDADMQNIKRTIMDVEAAKEIEQQAKAIVCFYRAVAEASHNVAMLHLVLSLSPVLHKNVAQNLELLDRREEASTMANDHRRALLAAIVRRDPDAAREASNEHLSYIEEVMLSVREEDSRLQRSLRRLKSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ6</accession>
    <name>B1KNQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325850.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3244"/>
    <dbReference type="EnsemblBacteria" id="ACA87514">
        <property type="protein sequence ID" value="ACA87514"/>
        <property type="gene ID" value="Swoo_3244"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3244"/>
    <dbReference type="eggNOG" id="ENOG5032WSG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145285_0_0_6"/>
    <dbReference type="OMA" id="FGPECFS"/>
    <dbReference type="OrthoDB" id="1884957at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="15973" checksum="360153B2EF6D762A" modified="2008-04-29" version="1" precursor="true">MKLNYGVVFLVIAAFITIFTAFAHLSCIYFGPECFSSQMAPSVIVESAKEGTLLAPLGTVFVSTIFIILGCYALSAADVVRKLPLLKLGIYSIAFLCIIRGVLPLQLWLRQPDKVSELVLYVGLVWLLTGLLYFFGFRAMGKIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNV4</accession>
    <name>B1KNV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325898.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3292"/>
    <dbReference type="EnsemblBacteria" id="ACA87562">
        <property type="protein sequence ID" value="ACA87562"/>
        <property type="gene ID" value="Swoo_3292"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3292"/>
    <dbReference type="eggNOG" id="ENOG5033B9T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136199_1_0_6"/>
    <dbReference type="OMA" id="FWQQRRQ"/>
    <dbReference type="OrthoDB" id="2020065at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021732">
        <property type="entry name" value="DUF3301"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11743">
        <property type="entry name" value="DUF3301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14473" checksum="6C030BB13059479D" modified="2008-04-29" version="1">MMTDFLFFAAVIVIAAFFWQLRQMAELSRIFANRECQKQKVQLLAVAMESARPSIGGSSGLTWKAKYLLEFSTDGINQYKAHIWMHGKTIQKVQWPIFPEPEWHEAPEARGSVGGSCGSRGSCNTGKCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY9</accession>
    <name>B1KNY9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327337.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4771"/>
    <dbReference type="EnsemblBacteria" id="ACA89020">
        <property type="protein sequence ID" value="ACA89020"/>
        <property type="gene ID" value="Swoo_4771"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4771"/>
    <dbReference type="eggNOG" id="COG3042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_908804_0_0_6"/>
    <dbReference type="OMA" id="CESLQGK"/>
    <dbReference type="OrthoDB" id="1924384at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005590">
        <property type="entry name" value="DUF333"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03891">
        <property type="entry name" value="DUF333"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766910" evidence="1">
        <location>
            <begin position="20"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="249" mass="26912" checksum="07448480111A7268" modified="2008-04-29" version="1" precursor="true">MIKITSLALVITATVALTACNPNEQTSTKADIEQAPSAVSMANPASEYCVSLGGKLEINNEAEGQVGICHLPSGEKIEEWTLYRKANKQEVTTAIDMANPASTYCESLQGKLALDTGVCTLPSGEALDQWDLFRRDHKQTKPAMGMANPASTYCESLQGKLALDTGVCTLPSGEALDQWDLFRRDHKQTKPAIGMANPAAKYCGSLQGKLALETGVCTLPSGEALDQWDLFRRDHKQTDPVKELLPITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD0</accession>
    <name>B1KPD0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323049.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84700">
        <property type="protein sequence ID" value="ACA84700"/>
        <property type="gene ID" value="Swoo_0401"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0401"/>
    <dbReference type="eggNOG" id="ENOG5032STK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2755629_0_0_6"/>
    <dbReference type="OMA" id="SGVIWVK"/>
    <dbReference type="OrthoDB" id="2035775at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009491">
        <property type="entry name" value="DUF1107"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06526">
        <property type="entry name" value="DUF1107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="70" mass="7990" checksum="D77294FD87CDF2FA" modified="2008-04-29" version="1">MRVFPVYAPKLIVKHARIFLSGVIWVKDLGRLEFDKGRFLLPRKSLPEVKQAVIELNDLIEAQSSEAKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPI8</accession>
    <name>B1KPI8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86141">
        <property type="protein sequence ID" value="ACA86141"/>
        <property type="gene ID" value="Swoo_1857"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1857"/>
    <dbReference type="HOGENOM" id="CLU_1342492_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="204" mass="22411" checksum="672F835924210AA9" modified="2008-04-29" version="1">MMNIAENMTNKVTDKVTEGVEIVVPAPAFEGNSMNVSTDVNYFSITPDVLSPWNTEIYRVDNGVLALTPSPCSSLTISFEPYKPSETSPVVLSEELQLLQRAVLIGKMSDKAIEAGWRFYENGIVFDEEQNASAYSVTSQVADNGLQVILTIEQVKETPVGGDTISFRYVASKDLPTPPFTDAQGQFTVHYSQDPLVGVRRPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ12</accession>
    <name>B1KQ12_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327442.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4876"/>
    <dbReference type="EnsemblBacteria" id="ACA89125">
        <property type="protein sequence ID" value="ACA89125"/>
        <property type="gene ID" value="Swoo_4876"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4876"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_1_5_6"/>
    <dbReference type="OMA" id="HKAQPVI"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="50"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="144" mass="15806" checksum="C20BAB4F5D97A6BC" modified="2008-04-29" version="1">MQEYIEFLKANPMLSLAWIGLFIGLIVSVFKSSVSKVTTVDHQQATLLINKQDAKVIDVREKAEFKKGHIIDAINVPLSEIKNNQISALEKFKASPIIMVCNAGMVSSQAAQLMVKAGFESVNNLKGGMGDWQSNNLPVTKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ16</accession>
    <name>B1KQ16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327446.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4880"/>
    <dbReference type="EnsemblBacteria" id="ACA89129">
        <property type="protein sequence ID" value="ACA89129"/>
        <property type="gene ID" value="Swoo_4880"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4880"/>
    <dbReference type="eggNOG" id="COG2861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041643_2_0_6"/>
    <dbReference type="OMA" id="VMLHMPM"/>
    <dbReference type="OrthoDB" id="1927281at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10936">
        <property type="entry name" value="CE4_DAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006837">
        <property type="entry name" value="Divergent_DAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30105">
        <property type="entry name" value="PTHR30105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04748">
        <property type="entry name" value="Polysacc_deac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766943" evidence="1">
        <location>
            <begin position="19"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="27747" checksum="64B933C16011E622" modified="2008-04-29" version="1" precursor="true">MRLTLIFLAVFISSFTHAAQVAIIIDDIGYRQSDEAVLTLPENITLSVLPHTPLGHSVASAAHERGHEIMVHLPMQALNGKALGPGGLTNTMGESELKKSIQSAFLSVPFAKGANNHMGSLLTQLEEPMLWVMESLKQQDLYFVDSMTTRFTKAGTTADQLGIPQLKRELFLDNDISAAALDRQFSKLITLAHNQGQIVAIAHPYPETIEFLKLNLPRLQKAGIKLVKTSELLPYRLASKERLKAEEELRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ85</accession>
    <name>B1KQ85_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0442</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0442"/>
    <dbReference type="EnsemblBacteria" id="ACA84740">
        <property type="protein sequence ID" value="ACA84740"/>
        <property type="gene ID" value="Swoo_0442"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0442"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_1_2_6"/>
    <dbReference type="OMA" id="FQEWPQV"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="12"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="198"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="385"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA84740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="562" mass="60683" checksum="1942AB80AFA9C7A7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ94</accession>
    <name>B1KQ94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323098.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0451"/>
    <dbReference type="EnsemblBacteria" id="ACA84749">
        <property type="protein sequence ID" value="ACA84749"/>
        <property type="gene ID" value="Swoo_0451"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0451"/>
    <dbReference type="eggNOG" id="COG5492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_276335_0_0_6"/>
    <dbReference type="OrthoDB" id="920610at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011460">
        <property type="entry name" value="DUF1566"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07603">
        <property type="entry name" value="DUF1566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005661838" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="690"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1152" mass="123349" checksum="7F9C4CB3605A4863" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA8</accession>
    <name>B1KQA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323112.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0465"/>
    <dbReference type="EnsemblBacteria" id="ACA84763">
        <property type="protein sequence ID" value="ACA84763"/>
        <property type="gene ID" value="Swoo_0465"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0465"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="REYPKMT"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="847"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="874"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="954"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="982"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1025" mass="110921" checksum="E43257B07C88B469" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB7</accession>
    <name>B1KQB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type I secretion outer membrane protein, TolC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0474</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323121.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0474"/>
    <dbReference type="EnsemblBacteria" id="ACA84772">
        <property type="protein sequence ID" value="ACA84772"/>
        <property type="gene ID" value="Swoo_0474"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0474"/>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012817_0_0_6"/>
    <dbReference type="OMA" id="SIKQMLF"/>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010130">
        <property type="entry name" value="T1SS_OMP_TolC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01844">
        <property type="entry name" value="type_I_sec_TolC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766949" evidence="3">
        <location>
            <begin position="28"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="470" mass="52449" checksum="49C026FBFCFD58AE" modified="2008-04-29" version="1" precursor="true">MNTSSIRQLKRSALALAVSALIIPASAYSQTLEQAVAHTLDTNPEIRIAFNRFKAREEQVNQAIAGYMPTVDLTGGYGWEQTNSPSTRRKKNQGDVDSDGVIELERGEAGFSIKQMLFDGFYTSSEVDRFSFEASADQWALFSAAEDMALDVAKVYINYIRTEQVMTLAEKNLLSHQDIYEQIKQRTDSGLGSTADLSQITGRLARANANLISAKNNFYDAKAQFIKVVESQPENLIVPVPDDDMMPEDLNTSIQLAQENHPILKSASSDIEAAKNEKSSAQSNYYPKLSLDLAGNWNNDVDGEDGFSNIASSSVGGHSNDLVAMVRIKYNLFSGGKDLAREKEAAYKIGEAKEIRQRAHRQVVEGVNLAWNAYELLEPQKLYIRDHVIAAKDTQVAYSQQFNLGQRTLLDLLDTENELFEARKDYLEAEYDQVISEYRVLNATGRLLESLRVTPPDVWQGERNYEGGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD2</accession>
    <name>B1KQD2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xerC</name>
        <name evidence="15" type="ordered locus">Swoo_0489</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323136.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0489"/>
    <dbReference type="EnsemblBacteria" id="ACA84787">
        <property type="protein sequence ID" value="ACA84787"/>
        <property type="gene ID" value="Swoo_0489"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0489"/>
    <dbReference type="eggNOG" id="COG4973">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_9_0_6"/>
    <dbReference type="OMA" id="HSFASHM"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011931">
        <property type="entry name" value="Recomb_XerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02224">
        <property type="entry name" value="recomb_XerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="105"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA84787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="33911" checksum="D86AEEB038088D3B" modified="2008-04-29" version="1">MEVNWFQHFESYLSAERQLSKHTVRNYLFELNRVDQLLDDSTSWLSVSREQIQSAMSQLHRRGLSPRSLSLTLSAVKQFCEFLLREGVIQTNPAINLSAPKQNKPLPKNMDPDSVSHLLEIDGDDPLSLRDKAIMELFYSSGLRLAELAALNISDIQFSERLVKVLGKGGKERILPIGKMAISAIDKWLACRRLIPCEHDALFITNKGTRLAHRSIQARLSKWGQEQALNMRVHPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQIYTSLDFQHLAKVYDGAHPRAAKAKKDKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD9</accession>
    <name>B1KQD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323143.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0496"/>
    <dbReference type="EnsemblBacteria" id="ACA84794">
        <property type="protein sequence ID" value="ACA84794"/>
        <property type="gene ID" value="Swoo_0496"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0496"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_47_2_6"/>
    <dbReference type="OMA" id="HALEVHC"/>
    <dbReference type="OrthoDB" id="2063007at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="103" mass="11695" checksum="743E8152D6A6910F" modified="2008-04-29" version="1">MKVTNSKQLSAYLKDARLNMKLSQSKVGNKVGIRQDTVSSFEQNPDSTKLETLFKILSALNLELDIKVRNPELAHSNVKDKPLDDHQAQATATAQNQEWKEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT0</accession>
    <name>B1KQT0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326021.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3418"/>
    <dbReference type="EnsemblBacteria" id="ACA87686">
        <property type="protein sequence ID" value="ACA87686"/>
        <property type="gene ID" value="Swoo_3418"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3418"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_972852_0_0_6"/>
    <dbReference type="OMA" id="KEHTDEN"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="286" mass="32416" checksum="03048FD3B7816F6E" modified="2008-04-29" version="1">MKINKDRLSAFYQVAISKNFHTAADALCITQPALSQRVLKLEQEIETTLFIRGNDGVTLTQSGLLLLEYVRNLSSMELEVLAKISGRSNGGRCGTLRVAAYSSILRSVIMPALKPILDSSEDIHVEFFSREMRDLPSMLKTGEADFIVLDHFNDLINFNKVKIGEEEIVHARHKEHTDENQVFLDHDIQDMTTFSFFKSQGLGDVSLKRCYYDDIYGVIDGVKLGFGQAIVSRHLISDLNDIEIIPYPHIVSNPLVLYYHSNQYLTSLYQEVIDTLKNRAALFLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQX5</accession>
    <name>B1KQX5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3465"/>
    <dbReference type="EnsemblBacteria" id="ACA87731">
        <property type="protein sequence ID" value="ACA87731"/>
        <property type="gene ID" value="Swoo_3465"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3465"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014586_0_0_6"/>
    <dbReference type="OMA" id="IQGQSWG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764766" evidence="2">
        <location>
            <begin position="24"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="745"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="943" mass="106835" checksum="DFE9E9E5D0BB97E7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQY1</accession>
    <name>B1KQY1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326071.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3471"/>
    <dbReference type="EnsemblBacteria" id="ACA87737">
        <property type="protein sequence ID" value="ACA87737"/>
        <property type="gene ID" value="Swoo_3471"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3471"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_37_1_6"/>
    <dbReference type="OMA" id="IAIYYGK"/>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="33715" checksum="AD241D80BC82A4EE" modified="2008-04-29" version="1">MSRRLPPLNSVKAFEAAARHLSFTRAAEELFVTQAAVSHQIKALEEYLGLKLFRRKNRSLLLTEEGQGYFLDIKDIFVQLAEATDRLLARSAIGSLTVSTSPSFAIQWLVPRLAKFSEKNPDIDVRIKAVDDEDGSLSDDVDVAIYYGQGNWAGLRADKLKNEVLIPVCSPMLLSGPKPLEKPSDLKNHTLLHDTSRHNWQAWFRQCGINDINVNQGPIFSHSSLVLQAAAHGQGVALGFSVLATPDIKAGRLVCPFPEVLVSKNAYYLVCQQNHSDIGKIAAFREWMLDMFEEESRSELLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR50</accession>
    <name>B1KR50_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent protease La (LON) domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323215.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0571"/>
    <dbReference type="EnsemblBacteria" id="ACA84867">
        <property type="protein sequence ID" value="ACA84867"/>
        <property type="gene ID" value="Swoo_0571"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0571"/>
    <dbReference type="eggNOG" id="COG2802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048359_3_1_6"/>
    <dbReference type="OMA" id="PNCHKTM"/>
    <dbReference type="OrthoDB" id="1474822at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="21929" checksum="D62E6ED7F047482B" modified="2008-04-29" version="1">MRTQEMALITRDALLLPDGRLELRLVSPNHLKMIADVYKGKYPLAFGMLKANGNPPCYSSVTQCEIIDFNQLDDNSLSIVLEGKQRVKILSAARQRSGVWMARTLPSCNWSEEPIQGEFELISAALEQFYEVNPDLFELYSNVHLEDASWVSQRWLEVLPLYNKDKLKLMNQPDCHQTMEFVLELIKSHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR67</accession>
    <name>B1KR67_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="5 7">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0588</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="5 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0588"/>
    <dbReference type="EnsemblBacteria" id="ACA84884">
        <property type="protein sequence ID" value="ACA84884"/>
        <property type="gene ID" value="Swoo_0588"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0588"/>
    <dbReference type="eggNOG" id="COG1091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045518_0_0_6"/>
    <dbReference type="OMA" id="RMPLMFG"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="UniPathway" id="UPA00281"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009243">
        <property type="term" value="P:O antigen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="8">
        <location>
            <begin position="24"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="327" mass="35861" checksum="F12786A524036C92" modified="2008-04-29" version="1">MVEKIIRLERINNNQRIIGDKVARVMITGSTGLLGRAVVKQLKQTDEHLLIATGFSRAETGIYKLDLTDEEAISEFIGVHQPDVIIHCAAERRPDISEQSPEAALALNLGATGALAKAAKQQGTWLIYISTDYVFDGTEPSYSEADKPNPVNFYGESKLQGEQALLATASDFAVLRLPILYGEVEKIEESAVLVLLNQLLDSTPQNVDNWAVRSPTSTQDIALAIEQMIGLHLKGEDLNGIYHFSAKQTMSKYQMLLVLAELFELNSEHLTPISSPMDTAKRPHDCTLSCQRLTELGIASQIAFKEGVKESLVSSQNALSLIGLTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR69</accession>
    <name>B1KR69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Two component transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0590"/>
    <dbReference type="EnsemblBacteria" id="ACA84886">
        <property type="protein sequence ID" value="ACA84886"/>
        <property type="gene ID" value="Swoo_0590"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0590"/>
    <dbReference type="eggNOG" id="COG4567">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_6_6"/>
    <dbReference type="OMA" id="RRLEWEH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="20976" checksum="3230C407A4A33BE6" modified="2008-04-29" version="1">MMGYKLLIIEDDLALAGVLERRMSRHGFSCIQAHDASKALLDARQFKPTHILLDMKLAQDNGLNLISPLRRSLPDVVMVLLTGYASIATAVEAIRLGADNYLAKPVDTATLLSALTDTQIKGGAVEINELDEQPLNPKRLEWEHIQQVLNMNKGNVSETARQLGMHRRTLQRKLLKKPTLDNRQSETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR82</accession>
    <name>B1KR82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase A24A prepilin type IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0603"/>
    <dbReference type="EnsemblBacteria" id="ACA84899">
        <property type="protein sequence ID" value="ACA84899"/>
        <property type="gene ID" value="Swoo_0603"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0603"/>
    <dbReference type="eggNOG" id="COG4960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057101_9_3_6"/>
    <dbReference type="OMA" id="TGNERWI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="3">
        <location>
            <begin position="7"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="17597" checksum="0B6768958DA828A1" modified="2008-04-29" version="1">MLAIASLLLVLVICCLTDICKRRISNIGCFATLIICVWLAASQQLLIEGFLTGSLIFALSLVLFRFRWLAAGDGKLASALAVALPLSQLPVALMLTLICGGVLAVIYLIKYRVIQKIPRGEDLGLPYGIAISLGFYIPILAFYLGELEGASQTSLLATAVVNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRE6</accession>
    <name>B1KRE6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipid A biosynthesis myristoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.243</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Kdo(2)-lauroyl-lipid IV(A) myristoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lpxM</name>
        <name evidence="7" type="ordered locus">Swoo_2069</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dodecanoyl-(Kdo)2-lipid IVA + tetradecanoyl-[ACP] = alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid A + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:28438"/>
            <dbReference type="Rhea" id="RHEA-COMP:9648"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:58540"/>
            <dbReference type="ChEBI" id="CHEBI:61524"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78477"/>
            <dbReference type="EC" id="2.3.1.243"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis; KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.243" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324698.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2069"/>
    <dbReference type="EnsemblBacteria" id="ACA86353">
        <property type="protein sequence ID" value="ACA86353"/>
        <property type="gene ID" value="Swoo_2069"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2069"/>
    <dbReference type="eggNOG" id="COG1560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049421_1_0_6"/>
    <dbReference type="OMA" id="QMFATAP"/>
    <dbReference type="OrthoDB" id="1106624at2"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00360">
        <property type="reaction ID" value="UER00486"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019107">
        <property type="term" value="F:myristoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01944">
        <property type="entry name" value="Lipid_A_LpxM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011921">
        <property type="entry name" value="Lipid_A_MsbB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02208">
        <property type="entry name" value="lipid_A_msbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="6">
        <location>
            <begin position="137"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="35420" checksum="D0802083979963B0" modified="2008-04-29" version="1">MSRKPKYFNRSFHASLLHPKYWLTWIGILILVIFGLMPAWFRDPLARLLAKLVMKIAKKPLSVARVNLTTCFPDKSSDEIEALIKDNVENFVMILLAQSELLVRSKANIIRRVNLHGFEHVTRAREAGQPVIFIMPHVWGIEYAGLRLNLELSMVSMAKAHRNGLFNWFNNRMRSSQGGNIYMREAGIRALLSELKNDNSFFYLPDEDLGPDKSVFAPFLGTVKATLPVVGRLAQAGNAQVLPVKIGYDQTSRRYELTVMPAISPDEMQGKENEAIALNKAVEQVIQAYPEQYMWFLKVLKTRPEGESPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRE7</accession>
    <name>B1KRE7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324699.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2070"/>
    <dbReference type="EnsemblBacteria" id="ACA86354">
        <property type="protein sequence ID" value="ACA86354"/>
        <property type="gene ID" value="Swoo_2070"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2070"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_808662_0_0_6"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765148" evidence="1">
        <location>
            <begin position="21"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="36936" checksum="324E1AE89D320E35" modified="2008-04-29" version="1" precursor="true">MKVKSLLLSVVLFSGVGVVAGASYTEIEQGKVAVANRASGTVSIINAQTDTVVSTLQLPASSATPEPMYVVYKENRLYVGDRANNRIVVYDSFGFNLLSTISTGQGVFHMWAAKNAQMLLVNNDIDKTVTVIDTNSLSVLNTLSLPADLIEQGFKPHDVFVSDNGRSAFVSLVGGGSGDDYVIKLSIKHNRELARKKVGGDPHLFISPLKRKTLYVPSQESGTVLALNTKNLATRYQLDVPNAHGIFAQERRLYVTNIADGGSQGLYTIDAKRRHIIDTDNAPYGAPHNITVTANGKKIYVTHSGATQNKVSVFETVPGVALPSFSTEVTVEGNPFGLAYIPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG7</accession>
    <name>B1KRG7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisC</name>
        <name evidence="8" type="ordered locus">Swoo_2090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324719.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2090"/>
    <dbReference type="EnsemblBacteria" id="ACA86374">
        <property type="protein sequence ID" value="ACA86374"/>
        <property type="gene ID" value="Swoo_2090"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2090"/>
    <dbReference type="eggNOG" id="COG0079">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_1_6"/>
    <dbReference type="OMA" id="IWLNANE"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="7">
        <location>
            <begin position="49"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="348" mass="38077" checksum="0F17875A839D2FD4" modified="2008-04-29" version="1">MSNIKQRPLAQRLARPELLELEVYQSARRIGGRGDIWINANESPFNNSELASLNRYPECQPPELISAYSRYSGVSEQNIITGRGADEAIELLIRTFCIPGIDSIASFGPTYGMYAISAKTFNVGVKSLSLTADYQLPKDIVNQTQGAKLVFICNPNNPTGTVIDVENIEQVLTKLPESIVVVDEAYIEFCPEYSVAHLIEKYDNLVVLRTLSKAFSLAGARCGFLMANPYICDMVMRVIAPYPVPLPVSQLATAALSDSGIKLMRQQVKSLKSCGARLSDTLQSIGAKVLPANGNFVLAKFQTSTVSEKLHSAGIVARAYNDPKLANCIRFSFSNQSDTDAIINILNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH0</accession>
    <name>B1KRH0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324722.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2093"/>
    <dbReference type="EnsemblBacteria" id="ACA86377">
        <property type="protein sequence ID" value="ACA86377"/>
        <property type="gene ID" value="Swoo_2093"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2093"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_4_6"/>
    <dbReference type="OMA" id="HFSNRFR"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="187"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="287" mass="33655" checksum="E939F44968D00E17" modified="2008-04-29" version="1">MSENHNKHISFNDSHKICFRQHALTEYLSWAHYQNSEERLFYINDKQHTLSMYLSGGYETHRTDIQADFGGPGRFSLMPKDSESRWQLGIPQQFMHLYFDDNYLKQLALKVFDMDPRTIEVPELTFFENPGLESLFRYQIANIGWHSQSHLALEQITNTVLVSMLQSSGLTKSLNRVKGGLAPHIARLISDYMHQHFHRQIYLCELADLAQLSEYHFCRMFKESFARTPQEYLTYIRIEQVKHRLKTSAQSLSDIALDCGFANQSHMGRYFKKQFGITPRAFQKSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH4</accession>
    <name>B1KRH4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Helicase c2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324726.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2097"/>
    <dbReference type="EnsemblBacteria" id="ACA86381">
        <property type="protein sequence ID" value="ACA86381"/>
        <property type="gene ID" value="Swoo_2097"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2097"/>
    <dbReference type="eggNOG" id="COG1199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012117_2_0_6"/>
    <dbReference type="OMA" id="VVTNHAM"/>
    <dbReference type="OrthoDB" id="679382at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="21"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="644" mass="72090" checksum="762C84944B0AD267" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRP9</accession>
    <name>B1KRP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleoside-specific channel-forming protein Tsx</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326147.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3550"/>
    <dbReference type="EnsemblBacteria" id="ACA87814">
        <property type="protein sequence ID" value="ACA87814"/>
        <property type="gene ID" value="Swoo_3550"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3550"/>
    <dbReference type="eggNOG" id="COG3248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962051_0_0_6"/>
    <dbReference type="OMA" id="KSTGWGY"/>
    <dbReference type="OrthoDB" id="914393at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003055">
        <property type="entry name" value="Channel_Tsx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018013">
        <property type="entry name" value="Channel_Tsx-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036777">
        <property type="entry name" value="Channel_Tsx-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03502">
        <property type="entry name" value="Channel_Tsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01277">
        <property type="entry name" value="CHANNELTSX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111364">
        <property type="entry name" value="SSF111364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765155" evidence="5">
        <location>
            <begin position="24"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="277" mass="30774" checksum="5E1894A263E23A13" modified="2008-04-29" version="1" precursor="true">MKNVKTIALATALTATMAAPAFAADRSDLRGGDYGWMQFNAMYAVNELPRDGSTDNGHDYLEMEFGGRAGIVDLYGYVDVFNLTNRDYGDKGAGKGSSKIFMKFAPRFSIDAMTGWDLSVGPIQEVYFSTLFNWDDRVGEGVNSTFWGLGADVMVPWLGKTGMNLYGYYDLNNKEWNGYQFSMNWFKPVVNFDNGTFIAFQGYVDYQFGADAVDDEFVPTTSSGGAAYFGLHWHSDNYALGYGLKGYNDVYLLKDDGGIVGLETTGFAHYFTATYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRS3</accession>
    <name>B1KRS3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ordered locus">Swoo_3574</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3574"/>
    <dbReference type="EnsemblBacteria" id="ACA87838">
        <property type="protein sequence ID" value="ACA87838"/>
        <property type="gene ID" value="Swoo_3574"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3574"/>
    <dbReference type="eggNOG" id="COG0782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101379_2_0_6"/>
    <dbReference type="OMA" id="TWLTQEA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="16961" checksum="03285675A285ACF4" modified="2008-04-29" version="1">MTIVGADQLRKELDYLKFEKRPKIAEAIGEARELGDLKENAEYHAAREEQGLCEARVRDLEGKLSNAQIIDVTKMQNTGRIIFGTTVTILNIDTDVETTYRIVGDDEANIKENLLSVSSPIARGLIGKNVDDEVTISTPGGMTEYEITAVEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ0</accession>
    <name>B1KCZ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322665.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0015"/>
    <dbReference type="EnsemblBacteria" id="ACA84316">
        <property type="protein sequence ID" value="ACA84316"/>
        <property type="gene ID" value="Swoo_0015"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0015"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003547_0_0_6"/>
    <dbReference type="OMA" id="IIPQQNW"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766954" evidence="1">
        <location>
            <begin position="24"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="982"/>
            <end position="1046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1069" mass="118960" checksum="C94BFF8E6FDECF30" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD15</accession>
    <name>B1KD15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87850">
        <property type="protein sequence ID" value="ACA87850"/>
        <property type="gene ID" value="Swoo_3586"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3586"/>
    <dbReference type="eggNOG" id="ENOG50306RB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107574_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767253" evidence="1">
        <location>
            <begin position="34"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="19652" checksum="EB83B3DC9B8CCD63" modified="2008-04-29" version="1" precursor="true">MTMLIKKITTATLSSLMVISAAFSTLAITPVQAEVDRSLSQTYGYDGQQVLLDMDVGSAEVFATDDKEIRVEVLVSQSDSSWFSFWDSVDLADVELDVDQASKRITLKLNDQDDLKQEWKIYLPREAAVNLNVGVGQVEVNNMESDVDIDLGVGHAQVKHSIIYHSVSLESGVGEVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD22</accession>
    <name>B1KD22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326190.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3593"/>
    <dbReference type="EnsemblBacteria" id="ACA87857">
        <property type="protein sequence ID" value="ACA87857"/>
        <property type="gene ID" value="Swoo_3593"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3593"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024054_0_0_6"/>
    <dbReference type="OMA" id="NEFMICA"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764695" evidence="3">
        <location>
            <begin position="24"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="41"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="650" mass="70217" checksum="67E0EFA148F13902" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDH2</accession>
    <name>B1KDH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323320.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0677"/>
    <dbReference type="EnsemblBacteria" id="ACA84973">
        <property type="protein sequence ID" value="ACA84973"/>
        <property type="gene ID" value="Swoo_0677"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0677"/>
    <dbReference type="eggNOG" id="COG5589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1712034_0_0_6"/>
    <dbReference type="OMA" id="EYSTEQW"/>
    <dbReference type="OrthoDB" id="1575837at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012659">
        <property type="entry name" value="CHP02444"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09523">
        <property type="entry name" value="DUF2390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02444">
        <property type="entry name" value="TIGR02444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="17530" checksum="069B3DF0B167FC0A" modified="2008-04-29" version="1">MTYLNQFDISLWQACDTFYLKHQAQCLQLQDEHEVNINLLLLSIWLDKQTYRLQDQAWSQLKLEIQQWEERVLLPYRKLRKLSKNSLAETEYQQMLDVELMLERKSQALILHKLRLLPHEGTRSNFEIFLELYQLDSSNYLELAV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDP2</accession>
    <name>RL25_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplY</name>
        <name type="ordered locus">Swoo_2155</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324784.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDP2"/>
    <dbReference type="SMR" id="B1KDP2"/>
    <dbReference type="STRING" id="392500.Swoo_2155"/>
    <dbReference type="EnsemblBacteria" id="ACA86439">
        <property type="protein sequence ID" value="ACA86439"/>
        <property type="gene ID" value="Swoo_2155"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2155"/>
    <dbReference type="eggNOG" id="COG1825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137946_0_0_6"/>
    <dbReference type="OMA" id="HAGKFPA"/>
    <dbReference type="OrthoDB" id="1864712at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01336">
        <property type="entry name" value="Ribosomal_L25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020055">
        <property type="entry name" value="Ribosomal_L25_short"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142598" description="50S ribosomal protein L25">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01336"/>
        </source>
    </evidence>
    <sequence length="95" mass="10661" checksum="4CFDCF63966F11DE" modified="2008-04-29" version="1">MSYTIAAQVRTEIGKGSSRRLRHADKVPAVIYGPGKEPVAIVFDHKDIINIQENEDFYTSTLTINLDGSDVKVSVKAMQRHAFKPLIEHVDFTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ0</accession>
    <name>B1KDQ0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WIF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324791.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2163"/>
    <dbReference type="EnsemblBacteria" id="ACA86447">
        <property type="protein sequence ID" value="ACA86447"/>
        <property type="gene ID" value="Swoo_2163"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2163"/>
    <dbReference type="eggNOG" id="COG3249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041769_1_0_6"/>
    <dbReference type="OMA" id="RKDPQQI"/>
    <dbReference type="OrthoDB" id="1323839at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018642">
        <property type="entry name" value="DUF2066"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003306">
        <property type="entry name" value="WIF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09839">
        <property type="entry name" value="DUF2066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50814">
        <property type="entry name" value="WIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767273" description="WIF domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="WIF" evidence="2">
        <location>
            <begin position="318"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="369" mass="40757" checksum="C5A776F35AA6E9D6" modified="2008-04-29" version="1" precursor="true">MLKTLFKASLLYTSCLFIQFNSLNAAEVTQLDQSLVPVETRSAAERNKAISLGLQHVILKNSGSAAALSNPSVKAKVKSPNSLIRQFGYDEVDGELLLKVNFDHKRILELLREAQLPVWGKQRPLTLVWLVEESSGERKILNDASPVESRTLFQKDAEAKGVPLLFPLMDLDDNMQISVSDVRGMFVNQIELASQRYQADYFVVASMTPNADGVEYSVSLFSKGAEQGGTTPLVSKQQQVSDTEAAVNGIISTVSEYYVSRYAIADSGEQLTSSVTFVDITEMKQLVAIEKYLKQLSAVKAVHISQLQGTSVKYALELFGTLDDLHRLMALDPRIIEASGGYQGDIGRDDNLNSLDPALVNELEYRWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDS7</accession>
    <name>B1KDS7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphotransferase system, phosphocarrier protein HPr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2192</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324818.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2192"/>
    <dbReference type="EnsemblBacteria" id="ACA86474">
        <property type="protein sequence ID" value="ACA86474"/>
        <property type="gene ID" value="Swoo_2192"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2192"/>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136230_2_3_6"/>
    <dbReference type="OMA" id="APHGIHT"/>
    <dbReference type="OrthoDB" id="404807at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002114">
        <property type="entry name" value="PTS_HPr_Ser_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00589">
        <property type="entry name" value="PTS_HPR_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPr" evidence="4">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="85" mass="9261" checksum="0A1E331E328C392B" modified="2008-04-29" version="1">MYEKSVTITAKHGIHTRPAALLVKEAKTYDCDVLVECNGKQASAKSLFKLQTLGLYHGITVKVFAEGPQAEQAVEKVSELLITLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU2</accession>
    <name>B1KDU2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="6">RF MTase</shortName>
            <ecNumber evidence="6">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prmC</name>
        <name evidence="9" type="ordered locus">Swoo_3684</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326276.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3684"/>
    <dbReference type="EnsemblBacteria" id="ACA87944">
        <property type="protein sequence ID" value="ACA87944"/>
        <property type="gene ID" value="Swoo_3684"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3684"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_3_0_6"/>
    <dbReference type="OMA" id="FDARYWE"/>
    <dbReference type="OrthoDB" id="1816476at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="7">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="120"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="186"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="280" mass="31476" checksum="E0A6EC42BAE9181D" modified="2008-04-29" version="1">MYQTLSEALAWASPQLLDVSDTPKLDAEVMLLHIIHKQRGYLYTWPDERLTSEQIDDYTKMVGRRVIGTPIAHIVGEREFWSLPFMVNPTTLIPRPDTEILVETALNLPLAEAAKVLDLGTGTGAIALSLAYEKPSWQITAVDKIIEAVALAKANRSHLKLPQVDIIQSDWFDSVNCYDFNLIVSNPPYIDEEDSHLEEGDVRFEPHSALTAPEHGFADLYHIADCARDYLAPGGYLLLEHGFGQALQLRDKMIELGYENVATVRDFGSNDRCTLGRWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE05</accession>
    <name>B1KE05_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326339.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3748"/>
    <dbReference type="EnsemblBacteria" id="ACA88007">
        <property type="protein sequence ID" value="ACA88007"/>
        <property type="gene ID" value="Swoo_3748"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3748"/>
    <dbReference type="eggNOG" id="COG4564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_6_6"/>
    <dbReference type="OMA" id="HVIRLDI"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="80"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="287" mass="32328" checksum="4FE811B2FB54D2F9" modified="2008-04-29" version="1">MVGTGIYIDDIDRDVVTLQNEINGYINQTFVVIFVLTVAGVVVVFFSGLFLQASERKLADVKLKALTNRIVDTQEVERQRVSRELHDGIIQMLVSTKYVVENAIFRLDKGEVATKELTQCEQYLDATINDVRRISRDLHPNLLEDHGLSAALSALIEDYRNRLNIDIAFEPLAINKLLPSDARTTLYRIAQEALTNIERHAHATKVTVKVKVNDVWFILSISDNGAGFDTQKLSRNKSPFVGIGLRNMAERISYFNGRLDIYSASSGTKVVAKLPKKLLKYSNSEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE06</accession>
    <name>B1KE06_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cache type 2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3749</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326340.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3749"/>
    <dbReference type="EnsemblBacteria" id="ACA88008">
        <property type="protein sequence ID" value="ACA88008"/>
        <property type="gene ID" value="Swoo_3749"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3749"/>
    <dbReference type="eggNOG" id="COG4564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084641_1_0_6"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033480">
        <property type="entry name" value="sCache_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17200">
        <property type="entry name" value="sCache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01049">
        <property type="entry name" value="Cache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Cache_2" evidence="7">
        <location>
            <begin position="42"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19690" checksum="CA97625FA276FAF8" modified="2008-04-29" version="1" precursor="true">MDFKQKIIALSILPLVLSMLIIVLALHYQSELLSEQSGASYREKILELRKQQLQSNIELAMGAISHIYQAASEEDLLAQKQVAEILNTLQHGDDGYFFVYSDRGVNIVHPRQPYRVGKDLWDWVDVSGNPLIQILISNAQQGGGFMNICGRSLQRGYWLRSLLTLSCWINGVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE25</accession>
    <name>B1KE25_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323358.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0716"/>
    <dbReference type="EnsemblBacteria" id="ACA85011">
        <property type="protein sequence ID" value="ACA85011"/>
        <property type="gene ID" value="Swoo_0716"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0716"/>
    <dbReference type="eggNOG" id="COG0306">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_3_3_6"/>
    <dbReference type="OMA" id="MQAFCIA"/>
    <dbReference type="OrthoDB" id="1329125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="422" mass="43698" checksum="CE0E22DD73DC0554" modified="2008-04-29" version="1">MVDVLVTNGPMLIAIAAAFGFLMAWGIGANDVANAMGTSVGSNAITIKQAIIIAMIFEFAGAYLAGGEVTSTIRKGIIDSAYFVDSPELLVYGMISALLAAGIWLIVASALGWPVSTTHSIIGAIVGFAAVGVGTEAVEWGKVGGIVGSWVVTPAISGFIAFMIFQSVQKLIFDTDNPLENAKRYVPFYMALAGFMMSLVTITKGLKHIGLHFSTAEAYGLAAVIALIVGFIGIFAIKRLKMNPGAGRQNQFDNVEKVFAILMVLTACCMAFAHGSNDVANAIGPLAAVVSVVHSGGEISSKAPLVWWILPLGAVGIVMGLAIFGKRVMQTIGKNITHLTPSRGFAAELAAASTVVIASGTGLPISTTQTLVGAVLGVGMARGIAAINIGVVRNIVVSWVVTLPAGAGLSIMFFFMIKGIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF4</accession>
    <name>B1KEF4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroloquinoline-quinone synthase</fullName>
            <ecNumber evidence="2">1.3.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Coenzyme PQQ synthesis protein C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Pyrroloquinoline quinone biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pqqC</name>
        <name evidence="4" type="ordered locus">Swoo_2251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = H(+) + 2 H2O + 2 H2O2 + pyrroloquinoline quinone</text>
            <dbReference type="Rhea" id="RHEA:10692"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
            <dbReference type="ChEBI" id="CHEBI:58778"/>
            <dbReference type="EC" id="1.3.3.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PqqC family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.11" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324875.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2251"/>
    <dbReference type="EnsemblBacteria" id="ACA86532">
        <property type="protein sequence ID" value="ACA86532"/>
        <property type="gene ID" value="Swoo_2251"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2251"/>
    <dbReference type="eggNOG" id="COG5424">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080136_0_0_6"/>
    <dbReference type="OMA" id="YYQISIP"/>
    <dbReference type="OrthoDB" id="1571811at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033732">
        <property type="term" value="F:pyrroloquinoline-quinone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00654">
        <property type="entry name" value="PQQ_syn_PqqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011845">
        <property type="entry name" value="PqqC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039068">
        <property type="entry name" value="PqqC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40279">
        <property type="entry name" value="PTHR40279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02111">
        <property type="entry name" value="PQQ_syn_pqqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 2" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TENA_THI-4" evidence="3">
        <location>
            <begin position="12"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="249" mass="29192" checksum="DFD65B9478507E04" modified="2008-04-29" version="1">MQAWTKEEFEQKLKDKGSLYHIHHPYHKMMHKGECSVEQIRGWVANRFYYQINIPVKDAAILANCRDVKTRRMWIQRIVDHDGSIEDNTLGGIEAWLKLGEAVGLNRQDMLDEKYILPGVRFAVDAYVNFARRASWQEAACSSLTEMFAPEIHQSRLNTWPENYPWIKSEGLSYFQMRLSQARRDVNHGLAITLAHFTTREQQEHALNILQFKLDILWSMLDAMTLAYQYERAPYSQLIDAPVYHKGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ7</accession>
    <name>B1KEQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3813</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3813"/>
    <dbReference type="EnsemblBacteria" id="ACA88072">
        <property type="protein sequence ID" value="ACA88072"/>
        <property type="gene ID" value="Swoo_3813"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3813"/>
    <dbReference type="HOGENOM" id="CLU_3257795_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="42" mass="4837" checksum="E6851EB42F6D0667" modified="2008-04-29" version="1">MNTNNKIELIEEALLENVSGGREEAFCFELCFEFCLSICFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX5</accession>
    <name>B1KEX5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323473.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0831"/>
    <dbReference type="EnsemblBacteria" id="ACA85126">
        <property type="protein sequence ID" value="ACA85126"/>
        <property type="gene ID" value="Swoo_0831"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0831"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_6"/>
    <dbReference type="OMA" id="RSGFEIC"/>
    <dbReference type="OrthoDB" id="1729688at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="122" mass="13284" checksum="D54B492892317E7F" modified="2008-04-29" version="1">MKRAKILIIDDDPVCTGLLLAVLGDDHQVFTANSGDGGIDIIDTQTPDLILLDITMPHVNGYQVLKHLKADPSKADIAVIVISSLVETSDKDFALKLGADDYMTKPVLPAVLQNKVEMFLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX8</accession>
    <name>B1KEX8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323476.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0834"/>
    <dbReference type="EnsemblBacteria" id="ACA85129">
        <property type="protein sequence ID" value="ACA85129"/>
        <property type="gene ID" value="Swoo_0834"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0834"/>
    <dbReference type="eggNOG" id="COG2841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165482_0_0_6"/>
    <dbReference type="OMA" id="PIDDEAM"/>
    <dbReference type="OrthoDB" id="2093541at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007420">
        <property type="entry name" value="DUF465"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038444">
        <property type="entry name" value="DUF465_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04325">
        <property type="entry name" value="DUF465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="81" mass="9284" checksum="D1D0F6C9B36DD2BF" modified="2008-04-29" version="1">MLGEDHSLIHEFPEYKDAIAKLIQSSDTFANSVKQYNALDKEIRELELNGAPIDDEAMHQLKHDRAVLKDSLYQCLALDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF06</accession>
    <name>B1KF06_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aromatic amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0863</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323504.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0863"/>
    <dbReference type="EnsemblBacteria" id="ACA85157">
        <property type="protein sequence ID" value="ACA85157"/>
        <property type="gene ID" value="Swoo_0863"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0863"/>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052043_1_1_6"/>
    <dbReference type="OMA" id="FFTIWGV"/>
    <dbReference type="OrthoDB" id="369689at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004694">
        <property type="entry name" value="Hydroxy_aa_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00814">
        <property type="entry name" value="stp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="423" mass="46202" checksum="B8BC576A2EDB64CC" modified="2008-04-29" version="1">MQEEVMNTQVESSSRQGWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVMMAIIIGPMTYLAHRGLSRFVCSSQKQSSDITHVVEEYFGVGAGKAITLLYFFAIYPIVLIYGVGITNTIDSFIVNQLGMASPPRWLLSGVLILAMMSVMVSGEKLMLKVTQFLVYPLVAILAFMSLYLIPSWKMDALTQIPTTGEFLGTVWLTIPVLVFAFNHSPAISQFSVSLKREHGVNAAKKADVILRNTSMMLVGFVMLFVFSCVLSLSPAQLAESKAQNLPILSYLANVHASGFVSYFGPIIAVIAIVSSFFGHYLGATEGLKGIITKQLRSSNKEVSDKKINKFILGFMFFTIWGVAIINPSILGMIEALGGPIIAAILYLMPMYAVYKVPALKAYRGRISNIFVIIAGLLAMTAILFGMMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF42</accession>
    <name>B1KF42_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324925.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2304"/>
    <dbReference type="EnsemblBacteria" id="ACA86583">
        <property type="protein sequence ID" value="ACA86583"/>
        <property type="gene ID" value="Swoo_2304"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2304"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_19_1_6"/>
    <dbReference type="OMA" id="TPHAKPH"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="24720" checksum="98DA31C136564903" modified="2008-04-29" version="1">MASQSQEKSGSSIKAVLFDLDGTLVDTAPDLVAALNLSLAQFNCPQVSLDKMRQVASDGSLALVKAAQPHLNEDKQFELQQGLLRHYTQINGQHSQLFDGISALLAYLDEHAIPYGIVTNKPARFTRPLLDVLGLSISMGTVVSGDSTLFSKPHIAPMLLAAQQIDCPAEQILYLGDAERDLLAADNAGMLGGIAMWGYIGSDATPQNWPSNFTFHSPQDVVELLAQLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF61</accession>
    <name>B1KF61_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2323</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324944.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2323"/>
    <dbReference type="EnsemblBacteria" id="ACA86602">
        <property type="protein sequence ID" value="ACA86602"/>
        <property type="gene ID" value="Swoo_2323"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2323"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_12_2_6"/>
    <dbReference type="OMA" id="VWAGSMC"/>
    <dbReference type="OrthoDB" id="357522at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025878">
        <property type="entry name" value="Acyl-CoA_dh-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12806">
        <property type="entry name" value="Acyl-CoA_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="43"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="163"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="279"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_C" evidence="9">
        <location>
            <begin position="479"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="585" mass="63234" checksum="D3F46A190721BE88" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFD4</accession>
    <name>B1KFD4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane lipoprotein lipid attachment site</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326439.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3851"/>
    <dbReference type="EnsemblBacteria" id="ACA88109">
        <property type="protein sequence ID" value="ACA88109"/>
        <property type="gene ID" value="Swoo_3851"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3851"/>
    <dbReference type="eggNOG" id="COG3417">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114013_0_0_6"/>
    <dbReference type="OMA" id="VINDTMQ"/>
    <dbReference type="OrthoDB" id="1513163at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014094">
        <property type="entry name" value="LpoB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13036">
        <property type="entry name" value="LpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02722">
        <property type="entry name" value="lp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764797" evidence="1">
        <location>
            <begin position="20"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="199" mass="21996" checksum="A11F4FE32FA884DD" modified="2008-04-29" version="1" precursor="true">MFKKSLVVALALLPLTACQTTTSYIDAQDKATNVVAALSYADFKEAADSMATELIASPLMVHPEPRGRYIIHISDVTNDTMQRIDTDQLVKSMRVKMLNSGKFLVTTAFNGEDSSTREMRKLKDSKMVNQASVKGDGQVYAPDFSLSGKIMQRNASLDSGDTRIEYYFQLSMTNIENGLAYWEGERVVGKVADGDSVSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE8</accession>
    <name>B1KFE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326453.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3865"/>
    <dbReference type="EnsemblBacteria" id="ACA88123">
        <property type="protein sequence ID" value="ACA88123"/>
        <property type="gene ID" value="Swoo_3865"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3865"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_1_6"/>
    <dbReference type="OMA" id="HSLACAF"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="22711" checksum="BF6BAE8FA9A4D8CE" modified="2008-04-29" version="1">MFGITDLWLFVISGIALNIMPGPDSLYVIGRSGAQGFRAGSTASFGIASGTLVHIFAAAFGLSAILATSATAFTVIKILGCCYLVYMGLSMILSRKDSAEESVVHRPTSQKKIFSQGFLTNVLNPKVALFFLAFVPQFIAYDAPNKVLSFLILGLIFNINGMIWCHLLAWSSASVGRRVKQSRRVNQLMNQCAGALFICFGIKLALSEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFH5</accession>
    <name>B1KFH5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribose 1,5-bisphosphate phosphokinase PhnN</fullName>
            <ecNumber evidence="3">2.7.4.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribose 1,5-bisphosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phnN</name>
        <name evidence="5" type="ordered locus">Swoo_3892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>alpha-D-ribose 1,5-bisphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:20109"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:68688"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 1,5-bisphosphokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.23" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326480.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3892"/>
    <dbReference type="EnsemblBacteria" id="ACA88150">
        <property type="protein sequence ID" value="ACA88150"/>
        <property type="gene ID" value="Swoo_3892"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3892"/>
    <dbReference type="eggNOG" id="COG3709">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102477_0_0_6"/>
    <dbReference type="OMA" id="RLIWLTG"/>
    <dbReference type="OrthoDB" id="1724909at2"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033863">
        <property type="term" value="F:ribose 1,5-bisphosphate phosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019634">
        <property type="term" value="P:organic phosphonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00836">
        <property type="entry name" value="PhnN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012699">
        <property type="entry name" value="PhnN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02322">
        <property type="entry name" value="phosphon_PhnN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GuKc" evidence="4">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="21556" checksum="45C11664E270D53D" modified="2008-04-29" version="1">MGRLFYVIGPSGSGKDTFIQAVRETWPDSILYAHRYITRCATAGGENHIELSQREFLYRKQKGLFSIDWQAHQHHYALGAEIDTWLNLGLDVVLNGSREYLGKMQDKFADRLFPVLMQVDDITLAERLRMRGRESEAQIIKRLARAQAHPLSLPERSITIDNSGSLEASLTQFSNYYQRLIRDSIPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK9</accession>
    <name>B1KFK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Formate dehydrogenase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_3926</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3926"/>
    <dbReference type="EnsemblBacteria" id="ACA88184">
        <property type="protein sequence ID" value="ACA88184"/>
        <property type="gene ID" value="Swoo_3926"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3926"/>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_4_0_6"/>
    <dbReference type="OMA" id="MTNHEMI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015942">
        <property type="term" value="P:formate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02790">
        <property type="entry name" value="MopB_CT_Formate-Dh_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02753">
        <property type="entry name" value="MopB_Formate-Dh-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041925">
        <property type="entry name" value="CT_Formate-Dh_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041924">
        <property type="entry name" value="Formate_Dh-H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006478">
        <property type="entry name" value="Formate_DH_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01591">
        <property type="entry name" value="Fdh-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="13">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="14">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="14">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="15">
        <location>
            <begin position="228"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA88184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="924" mass="101068" checksum="E8ECEC01DEBB7240" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFP0</accession>
    <name>B1KFP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0913"/>
    <dbReference type="EnsemblBacteria" id="ACA85206">
        <property type="protein sequence ID" value="ACA85206"/>
        <property type="gene ID" value="Swoo_0913"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0913"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037416_0_0_6"/>
    <dbReference type="OMA" id="MAEFWWG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="2">
        <location>
            <begin position="372"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="566" mass="64282" checksum="3A45744571B3ACF6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ7</accession>
    <name>B1KFQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323570.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0930"/>
    <dbReference type="EnsemblBacteria" id="ACA85223">
        <property type="protein sequence ID" value="ACA85223"/>
        <property type="gene ID" value="Swoo_0930"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0930"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_2_6"/>
    <dbReference type="OMA" id="DNCLIAV"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033444">
        <property type="entry name" value="MASE5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17178">
        <property type="entry name" value="MASE5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="257"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="390" mass="43983" checksum="3B4176C09698D1D3" modified="2008-04-29" version="1">MLEFSATSFKVISIGINANLPSFERQLKTETHLYLIKGAMWATVISLFMLLAILLNIYLQNSDISVFYEAIQMVSPLVMITFSGALAAYFVKRENIAIWGLYSYLFLLEIVWVYLVWRLFHFSSDKLPSYAALAGVESIIDILVLTIAIAFFPNRNLMLMGVLPLMVFSCYERVLVVPDQYLFPLTKFFCFLAIIVSGQKVLSSWFNKAILRNVEKQYLLAQFRRLALVDSLTDISNRRHFDEILLQEIRASERTGHPLGLVLIDVDYFKRLNDSAGHQSGDECLVEIAKILTVTANRPRDLAARYGGEEFVLLLPETDIAGCIEIAEALKRKLAVAKLPHPDSDIGSLVTISQGVTLWKEGMEAQELLECADSLLYQAKSSGRDRFIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFX4</accession>
    <name>B1KFX4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325023.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2403"/>
    <dbReference type="EnsemblBacteria" id="ACA86681">
        <property type="protein sequence ID" value="ACA86681"/>
        <property type="gene ID" value="Swoo_2403"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2403"/>
    <dbReference type="eggNOG" id="COG5470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131535_1_0_6"/>
    <dbReference type="OMA" id="ELMLIGP"/>
    <dbReference type="OrthoDB" id="1534521at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010753">
        <property type="entry name" value="DUF1330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07045">
        <property type="entry name" value="DUF1330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1330" evidence="1">
        <location>
            <begin position="50"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15843" checksum="F0287DC915744FB8" modified="2008-04-29" version="1">MKTISPSQKSFAELISGKVDDEPIVMVNLLKFKDQADYTKLASSHPDHALTITGKEAYAIYGEAVTPMVEEVGGQILWQGNTRFTFIAPDEETWDEVVLVQYPSRAAFLKMVTSGAYQKIVHHRDLSLDDSRLIETQPTNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG23</accession>
    <name>B1KG23_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325072.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2453"/>
    <dbReference type="EnsemblBacteria" id="ACA86730">
        <property type="protein sequence ID" value="ACA86730"/>
        <property type="gene ID" value="Swoo_2453"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2453"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131496_11_1_6"/>
    <dbReference type="OMA" id="YMREAFD"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="11056" checksum="9AE046732519F153" modified="2008-04-29" version="1">MANLTIQANIIAKPGKIQQVKTALLKLIELTRAEAGCVNYDLHQDNENPAHFMFYENWTSRELWQQHMSSAHIETYIAETQDCVEQFTLSEMTQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG38</accession>
    <name>B1KG38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325087.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2468"/>
    <dbReference type="EnsemblBacteria" id="ACA86745">
        <property type="protein sequence ID" value="ACA86745"/>
        <property type="gene ID" value="Swoo_2468"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2468"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_18_2_6"/>
    <dbReference type="OMA" id="RMTYLVA"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="397" mass="43465" checksum="6E5C4436E5DDA484" modified="2008-04-29" version="1" precursor="true">MATKKQIILPIAVISIGIGSFLAISALKKPPEEKEAVDNTPLVAVKQVKLEPMTFKVNSYGVVNAKYETELVSQVNGEIVFLSDTFVRGGFVKKGDILARIDSSDYDADLIDAEAKLASARATLVQEKAFGKVAEEEWKRIKDGVPTELSLRKPQLAQELAKLNSSEAGLKRAKRNVERTIIKAPYDALIESRNIGLGSYVSMGTKLGKVLSTHKAEIRLPLADKEIQYLVNKGKDADVTLVANLGGSKQEWAGKIVRSEGVIDSRSRMTYLVAEVIDPYGLQSDKSELRYGTYVTANISGTDAGDVVVMPRHLVINGQIAILDDDKKLRYKDVNVIRQSGAEVVISDGLTQNMEVIISALDYPVEGMKLALPEDKLLQQNSEGEESDTQLAMEEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB2</accession>
    <name>B1KGB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor plug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3992</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326578.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3992"/>
    <dbReference type="EnsemblBacteria" id="ACA88249">
        <property type="protein sequence ID" value="ACA88249"/>
        <property type="gene ID" value="Swoo_3992"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3992"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_1_1_6"/>
    <dbReference type="OMA" id="NYRTPYW"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764848" evidence="5">
        <location>
            <begin position="34"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="60"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="369"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="877" mass="94475" checksum="A8D7834499DEC591" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB9</accession>
    <name>B1KGB9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326585.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88256">
        <property type="protein sequence ID" value="ACA88256"/>
        <property type="gene ID" value="Swoo_4000"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4000"/>
    <dbReference type="eggNOG" id="ENOG5031EB9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125015_0_0_6"/>
    <dbReference type="OMA" id="DKHEYSS"/>
    <dbReference type="OrthoDB" id="1972737at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764850" evidence="1">
        <location>
            <begin position="23"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="182" mass="19750" checksum="FDB212E5B89CA2A2" modified="2008-04-29" version="1" precursor="true">MKFIKSTLAMATCFYLAGCASGAQVENMIYKGDKHEYSSEIKENVMLSSVTGGEETNPVWTSEISDEAFSGAIKQSLKNEGLYSEDGKYDLSVEMLEIDQPSFGFDMTVTTIVKYVLTDKASGEVIIDKEVNAPYTATVGDAFSGVKRLRLANEGSSQENIKGLLALLSELNLGIDQVSMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC0</accession>
    <name>B1KGC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipid A ABC exporter family, fused ATPase and inner membrane subunits</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4001</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326586.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4001"/>
    <dbReference type="EnsemblBacteria" id="ACA88257">
        <property type="protein sequence ID" value="ACA88257"/>
        <property type="gene ID" value="Swoo_4001"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4001"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_6"/>
    <dbReference type="OMA" id="ERQRMTI"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011918">
        <property type="entry name" value="ABC_MsbA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02204">
        <property type="entry name" value="MsbA_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="50"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="367"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="410"/>
            <end position="417"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="617" mass="67200" checksum="DA3B3932867B68D2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC9</accession>
    <name>B1KGC9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326595.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4010"/>
    <dbReference type="EnsemblBacteria" id="ACA88266">
        <property type="protein sequence ID" value="ACA88266"/>
        <property type="gene ID" value="Swoo_4010"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4010"/>
    <dbReference type="eggNOG" id="COG4559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_6"/>
    <dbReference type="OMA" id="KALCQEI"/>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="28135" checksum="E8DD849CF5FD4C8C" modified="2008-04-29" version="1">MIDIKHVSVRINHKPVLTNINLHIPSGKVTALLGPNGAGKSTLLKSLSQEVQLDAGNIALNDRPVQDFDRLELAKHLAVLPQHASLTFPFAVHEVVAMGLYPLTLSNKQGMELVDEQLNRLALTSLKYRSYPTLSGGEKQRVQLARVLTQLQQAQRPPILLLDEPTSALDLAQQHRVLSLAKELAHQHNYAVVVVLHDLNQASRYADNLVILERGQIVSQGTARTTLTLQTIKQVWQYEPQIVNAPGCETPLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGI4</accession>
    <name>B1KGI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323659.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1019"/>
    <dbReference type="EnsemblBacteria" id="ACA85312">
        <property type="protein sequence ID" value="ACA85312"/>
        <property type="gene ID" value="Swoo_1019"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1019"/>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_2_1_6"/>
    <dbReference type="OMA" id="INHAHLG"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="24953" checksum="C3F17F4BDCBC254C" modified="2008-04-29" version="1">MKVMILAAGRGERLRPLTDSLPKPLVCVAGKPLIVYHIERLAKAGFKDIVINHAWLGEKLIESLGDGTRWGVNIQYSHEATALETGGGIKKALSLLGHKPFLVINGDVFIDSLPELEEGDATHMLNGKLAHLWLVDNPSQHPKGDFSLKAGLVENKAIGDELTLTFSGMGIYHPSLFDGTSDAGFPLAPLLREKMALGLISGEHFPGFWCDVGTVARLDMLEKRQRDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM6</accession>
    <name>B1KGM6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323700.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85354">
        <property type="protein sequence ID" value="ACA85354"/>
        <property type="gene ID" value="Swoo_1061"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1061"/>
    <dbReference type="HOGENOM" id="CLU_1219044_0_0_6"/>
    <dbReference type="OrthoDB" id="2056331at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="26580" checksum="CB34ECF869AF2DFF" modified="2008-04-29" version="1">MRVYKFREKEDYIYYLSQIIADTVKYKARLKRYLLEINDLIESDPDAEVVEATAYESISDKSKALLYYLFNLFGDESKSAVSYRKFRKLLVKGASCLDVSFEQLTNEEAQISNSFNQHRNWGLHIPESLFTNQRQIHDITGTVIDKHKDTIPVEVYEHFEIQYLTSLKMELADVVSNIEVLEKRMMQDYLILAGTHFQVSLFHIKVKPYKIMDIVQASINTQTKKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX3</accession>
    <name>B1KGX3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2565</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325182.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2565"/>
    <dbReference type="EnsemblBacteria" id="ACA86842">
        <property type="protein sequence ID" value="ACA86842"/>
        <property type="gene ID" value="Swoo_2565"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2565"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_0_6"/>
    <dbReference type="OMA" id="YNPDPIV"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767048" evidence="5">
        <location>
            <begin position="38"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="59"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="361"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="843" mass="91357" checksum="6E8916A55304C42A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH15</accession>
    <name>B1KH15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4071</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326656.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4071"/>
    <dbReference type="EnsemblBacteria" id="ACA88327">
        <property type="protein sequence ID" value="ACA88327"/>
        <property type="gene ID" value="Swoo_4071"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4071"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_625346_0_0_6"/>
    <dbReference type="OMA" id="YYLDLAW"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="20"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="337"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="48936" checksum="163A8567B17A2625" modified="2008-04-29" version="1">MFFYYLDLAWRSIKKTPLLSLLMVLAISIGIGTTITSLNIYQMANINPAGDRSSQLYEVRLMSQGLDSWEEINEQITYQDSFNLRKNSIATRQSPMFRTGMAVQTDDDNFVPILEGARVADSDFFGLFSVEFLYGSSWGKQVDIDPAYQVVIREDLNKEVFGGENSVGRTIYLNQKPYQIVGVIKYWNPSPKYYDVNNGAFNDAERMFVPFSLAPIEEFESWGNNQSWKREDIVTYADRLASETHWNQYWVELNTPEQVKEYQLWLSNYIEQQKLIGRFEMPEAKADLSDVATWLKVNNVVPEDNKVLVGLSVLFLIVCLVNMLGLLLAKFLKRAPEVGVRRAIGASRAQIFAQHMVEVGVIGFFGGVIGLLWAWGSLSILSAHFKLEEALTQLGMSMWVLAPGVAIASALIAGLYPAWRICSTNPSVHLKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH60</accession>
    <name>B1KH60_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326701.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4116"/>
    <dbReference type="EnsemblBacteria" id="ACA88372">
        <property type="protein sequence ID" value="ACA88372"/>
        <property type="gene ID" value="Swoo_4116"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4116"/>
    <dbReference type="eggNOG" id="COG5361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_588792_0_0_6"/>
    <dbReference type="OMA" id="NATYWVL"/>
    <dbReference type="OrthoDB" id="1547344at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="450" mass="49636" checksum="59F6A4ED1DC1F2E1" modified="2008-04-29" version="1" precursor="true">MDMNSLNWLGGKRFTLAVICASLSAVLLSGCDDDTQEVVQKEVTPSPCFWVGPYNIDHPDRNFAYPDTGANYWHAGYKLPSGAKLTLNGQYPHARYMSLNSYRLDTSPASSLTDQNIVPDLGSFNPYLQGAERQLSPRDFTIEIAQGEPDGEEAPNTLYDYVGAGDKSVLLYRIYVTDEGRDGLGDVPLPAVELTLESGEVLVGEQACSALQVDADNLSIPLVPAQTYQQVRANPAVEPAQNPAVWRAAYNGTFGFQCAFLGRCDGMPERQVTFYANADNQYVSTFLNNDFGAVAVTRGKLPSIPKTLISVPTYDESDSQLRYWSICQNEYYSQAVTACLFDEELTVDEDGYFTVVTSLLADKPINATNECGHNYLPWTEQGDGFGRVIEGGENRLNEALLIVRNMLPKEDFHQAIQNTSTPGDEYAVMGDYLPTTEYMSTEEFESLGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH5</accession>
    <name>B1KHH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325200.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2583"/>
    <dbReference type="EnsemblBacteria" id="ACA86860">
        <property type="protein sequence ID" value="ACA86860"/>
        <property type="gene ID" value="Swoo_2583"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2583"/>
    <dbReference type="eggNOG" id="ENOG50304MY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064962_0_0_6"/>
    <dbReference type="OMA" id="YVYWAKQ"/>
    <dbReference type="OrthoDB" id="763221at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021928">
        <property type="entry name" value="DUF3541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12060">
        <property type="entry name" value="DUF3541"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767062" evidence="1">
        <location>
            <begin position="26"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="366" mass="41702" checksum="F31F2248440468E7" modified="2008-04-29" version="1" precursor="true">MSPTLKTSLLSLALFSITAITPAIAAKSDLELDTPTHQQVYDGIKSNLEDHLYQLPPRVQGHYGIRQYRMTGNDIYANAALVDLYAVTESQAFYACQLDKPGFIDTEAKKAISVLGKGPRAKARKKALKPFPEFLFYTDVLLRFSSRIDEFGLTGPCNDKLISTLKKANLEQGLTDKAMIKSWAAQLINYVYWAKQLGVGDYLSSYKQAFIEVYPNENDHKLSKKQFRNKLYGMTHFIFAASEYYQHQVDAKEFDWILKYFENNIERILKDATDDIIAEVGISFHLAGLSDNKVVSLTQNHIINAYDPKEQFILSPMGNPDMAMGEHRNVLAMMLLDWPKELHQGPYFHKIKATKKYLPKLVEIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL5</accession>
    <name>B1KHL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase associated with various cellular activities AAA_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325240.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2623"/>
    <dbReference type="EnsemblBacteria" id="ACA86900">
        <property type="protein sequence ID" value="ACA86900"/>
        <property type="gene ID" value="Swoo_2623"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2623"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_2_6"/>
    <dbReference type="OMA" id="FMARVSI"/>
    <dbReference type="OrthoDB" id="895310at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="36"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="237"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="33214" checksum="C9870E24140ED18A" modified="2008-04-29" version="1">MTQQNLSQIIKQLEIVLLGKPDQIKLALTCILAKGHLLIEDLPGMGKTSLSHGIAQTLGLSYQRVQFTSDMLPADILGVSIFDSEQSQFVFHPGPIFKQMILADEINRASPKTQSALLEAMAEHQITVDGVTHPLPNPFFVIATQNPSEQSGTFPLPESQLDRFMMRLSIGYPSADAELEMLKNHVQSPQSTTLPQCITQLELIELQQMVDKVSASDALLGYILALIDASRVQKEGFGLSPRASKALLQAAKAWAFIQGRTYLVPEDVQAVFSSVAEHRIRSSSQQQGEAISQKILSSINPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHM5</accession>
    <name>B1KHM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrate reductase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325250.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2633"/>
    <dbReference type="EnsemblBacteria" id="ACA86910">
        <property type="protein sequence ID" value="ACA86910"/>
        <property type="gene ID" value="Swoo_2633"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2633"/>
    <dbReference type="eggNOG" id="COG1140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_5_2_6"/>
    <dbReference type="OMA" id="VYFNWQT"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042126">
        <property type="term" value="P:nitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10557">
        <property type="entry name" value="NarH_beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029263">
        <property type="entry name" value="Nitr_red_bet_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038262">
        <property type="entry name" value="Nitr_red_bet_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006547">
        <property type="entry name" value="NO3_Rdtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14711">
        <property type="entry name" value="Nitr_red_bet_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01660">
        <property type="entry name" value="narH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="174"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="512" mass="58240" checksum="E74B7617648CABA9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHU6</accession>
    <name>B1KHU6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein HflK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4168</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">HflC and HflK could encode or regulate a protease.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">HflC and HflK may interact to form a multimeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the band 7/mec-2 family. HflK subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326753.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4168"/>
    <dbReference type="EnsemblBacteria" id="ACA88424">
        <property type="protein sequence ID" value="ACA88424"/>
        <property type="gene ID" value="Swoo_4168"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4168"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039173_1_0_6"/>
    <dbReference type="OMA" id="WNEPGGN"/>
    <dbReference type="OrthoDB" id="577287at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03404">
        <property type="entry name" value="SPFH_HflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010201">
        <property type="entry name" value="HflK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020980">
        <property type="entry name" value="Membrane_HflK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF2">
        <property type="entry name" value="PTHR43327:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12221">
        <property type="entry name" value="HflK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01933">
        <property type="entry name" value="hflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="7">
        <location>
            <begin position="69"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="379" mass="42084" checksum="50561B42BC31EAF6" modified="2008-04-29" version="1">MAWNEPGNKGKDPWGNKNGNDKGPPDLDEVFRNISKRFGGGKGNGSGSSFSSFSLIIVLGIAIVVWGLSGFYTVKEAEKGVALRFGQYVGEVEPGLQWKATFIDEVFPVNVNTVRSIPASGSMLTADENVVLVELDVQYRVVDAYRFLFSAVDANASLREATDSALRYVVGHNKMDDILTTGRDQIRRDTWAEVERIIEPYKLGIAIEDVNFLPARPPEEVKDAFDDAISAQEDEQRFIREAEAYARAIEPKARGQVQRMEQQANAYKEREILEARGKVARFELLLPQYKAAPEVTRERLYLDAMQTVMSGTSKVLVDSKSSNNMMYLPLDKLMQKNQSGAKPQKVNSAASLNSSSSTMGQNSMPIDSRPSRGERQGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHX9</accession>
    <name>B1KHX9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phage shock protein C, PspC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4201</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326786.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4201"/>
    <dbReference type="EnsemblBacteria" id="ACA88457">
        <property type="protein sequence ID" value="ACA88457"/>
        <property type="gene ID" value="Swoo_4201"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4201"/>
    <dbReference type="eggNOG" id="COG1983">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2828844_0_0_6"/>
    <dbReference type="OMA" id="SCLWTRV"/>
    <dbReference type="OrthoDB" id="2022704at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="73" mass="8176" checksum="90EC640DEB27EEA0" modified="2008-04-29" version="1">MSSLDSLSGYISRMKQPDTLVCGMAAMMADKFDWSCLWTRVVWALAVIMNPGLGLLVYFVLALVLPKWQKSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI18</accession>
    <name>B1KI18_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster insertion protein ErpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">erpA</name>
        <name evidence="7" type="ordered locus">Swoo_1203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for insertion of 4Fe-4S clusters for at least IspG.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </cofactor>
        <text evidence="5">Binds 1 iron-sulfur cluster per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323842.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1203"/>
    <dbReference type="EnsemblBacteria" id="ACA85496">
        <property type="protein sequence ID" value="ACA85496"/>
        <property type="gene ID" value="Swoo_1203"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1203"/>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069054_5_3_6"/>
    <dbReference type="OMA" id="YQLYFDE"/>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01380">
        <property type="entry name" value="Fe_S_insert_ErpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023063">
        <property type="entry name" value="FeS_cluster_insertion_RrpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="6">
        <location>
            <begin position="17"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="122" mass="13212" checksum="98BED2D1D44E8397" modified="2008-04-29" version="1">MSEEIAEQATEQDELPIQFTDAAASKVKTLLEEEENDALKLRVYVTGGGCSGFQYGFTFDEKVNEGDFTVEKQGVQLVVDPMSLQYLVGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK3</accession>
    <name>Y4243_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-binding protein Swoo_4243</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_4243</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326826.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIK3"/>
    <dbReference type="SMR" id="B1KIK3"/>
    <dbReference type="STRING" id="392500.Swoo_4243"/>
    <dbReference type="EnsemblBacteria" id="ACA88499">
        <property type="protein sequence ID" value="ACA88499"/>
        <property type="gene ID" value="Swoo_4243"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4243"/>
    <dbReference type="eggNOG" id="COG1660">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059558_1_1_6"/>
    <dbReference type="OMA" id="TVMSFGF"/>
    <dbReference type="OrthoDB" id="1603998at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00636">
        <property type="entry name" value="RapZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000130784" description="Nucleotide-binding protein Swoo_4243">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="56"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <sequence length="280" mass="32148" checksum="ED82DFEF7394FD2A" modified="2008-04-29" version="1">MKLVMVSGRSGSGKSVALRVLEDLGYYCVDNLPLPLMDTLLEQLKDSTELVAISVDVRNMHETELDKQLSNLPEGTELLSFFLNSSDEVLLKRYSETRRLHPLSRSKTSLKEAIDHERILLEPVSKLVDHYIDTSNLNIYDLSNQVREILLGSVDKELVINFESFGFKHGMPAEADFMFDVRFLPNPHWEPELRPMTGLDEPVQLFLSQQPTVNKFIWQIENLLETWLPHLERNNRSYLTIAIGCTGGQHRSVYVTEQLAKLFSQSKHTVQARHRELSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM0</accession>
    <name>B1KIM0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltrans_SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326843.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88516">
        <property type="protein sequence ID" value="ACA88516"/>
        <property type="gene ID" value="Swoo_4260"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4260"/>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014042_1_0_6"/>
    <dbReference type="OMA" id="YFPAIRQ"/>
    <dbReference type="OrthoDB" id="468283at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="30"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="335" mass="37174" checksum="DBC1D0BDA8982486" modified="2008-04-29" version="1">MSISSLLTSALAKRHDLLADAKLNNTDCYRVFHGTVEGHNGLNIDRYGDAWLIQTFHQTLTQDELNEIKLILENINPLTVIYNDRSDKNSRVMNALDTTDEAFAQSAQVMQENGIKFTSKLRHEGQDPLLFLDMRVGREYVHANSKNKTVLNLFSYTCGIGTAAAVGGAKRVINIDFSSFALEAGRKNAELNGVSEACQFIQSDAFPALRQLAGLKVGGRRNQKLPAYPKMTATQFDLVFLDPPRFAKSAFGTVDLINDYQGLFKPAMLATKKGGTIVCCNNVAKVEREAWFNALNRCVEKQGRSVASHQWLDCHEDFPSFDGNHPLKIVALTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIN1</accession>
    <name>B1KIN1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326854.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4271"/>
    <dbReference type="EnsemblBacteria" id="ACA88527">
        <property type="protein sequence ID" value="ACA88527"/>
        <property type="gene ID" value="Swoo_4271"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4271"/>
    <dbReference type="eggNOG" id="ENOG5033EY0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153204_1_1_6"/>
    <dbReference type="OMA" id="GLQFQID"/>
    <dbReference type="OrthoDB" id="2011411at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021482">
        <property type="entry name" value="DUF3135"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11333">
        <property type="entry name" value="DUF3135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="14437" checksum="8E5E8944C7690950" modified="2008-04-29" version="1">MSQQDFPDFDTLMEMAKNQPEKLENIFRDEVNSVIESASEEHHHRLRGLQFQVDAQRILAKNPMDACIRISKMMHRSLGDLHTTLNDFSLQHDHSNQVLNDLSDKQQDVSDILYFEGRKQPEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP6</accession>
    <name>B1KIP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326869.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88542">
        <property type="protein sequence ID" value="ACA88542"/>
        <property type="gene ID" value="Swoo_4287"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4287"/>
    <dbReference type="eggNOG" id="ENOG50337CT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156600_0_0_6"/>
    <dbReference type="OMA" id="QTEQMNE"/>
    <dbReference type="OrthoDB" id="1768790at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="14714" checksum="AE7D7EF45691EA59" modified="2008-04-29" version="1">MDNLSSNSSRKKPWIAFGVVLSIVVLFLGLLMMMPKGFKATHEEIGTGKPALVFVYDPNLAVSHTQTEQMNEARVHLGENVHLLLARVGTPEGEQLIATHRAGPAELLLFDSSGSLIKRQFAVKGANEIIHWVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIT4</accession>
    <name>B1KIT4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">Riboflavin kinase</fullName>
                <ecNumber evidence="12">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">FMN adenylyltransferase</fullName>
                <ecNumber evidence="12">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="12">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_1290</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ribF family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="12"/>
    <dbReference type="EC" id="2.7.7.2" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323928.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1290"/>
    <dbReference type="EnsemblBacteria" id="ACA85582">
        <property type="protein sequence ID" value="ACA85582"/>
        <property type="gene ID" value="Swoo_1290"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1290"/>
    <dbReference type="eggNOG" id="COG0196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048437_0_1_6"/>
    <dbReference type="OMA" id="HRGHQAI"/>
    <dbReference type="OrthoDB" id="1504821at2"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 12" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="13">
        <location>
            <begin position="183"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="34555" checksum="9D5C192EACAF7988" modified="2008-04-29" version="1">MELIRGINNILPAHHGCVLTIGNFDGVHRGHAEVISKLVKKARQLNVPATLMTFEPQPQEMFRGDSAPARLSTLRDKIVLLEELGIDRLVCINFNTKFAEMPAEDFIDKLLVKSLGVKYLVVGDDFCFGKERMGNFDMLRTSGEKHQFAVVSTQSFLLGDKRVSSTEIRGLLAKGKMEQARRLLGHPFTLSGRVAHGEEIGRTIGFPTANIALKRKVSPVRGVFAVKLYWDDSDVYDGVANVGFRPTVNGQKCQLEVHLFDFDGDLYGRTVEVELVAKIRDEQPFQSLEALRKQINNDADKAKALLGCDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV8</accession>
    <name>B1KIV8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5009 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323952.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1314"/>
    <dbReference type="EnsemblBacteria" id="ACA85606">
        <property type="protein sequence ID" value="ACA85606"/>
        <property type="gene ID" value="Swoo_1314"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1314"/>
    <dbReference type="eggNOG" id="COG4299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029171_4_0_6"/>
    <dbReference type="OMA" id="WHGFTFY"/>
    <dbReference type="OrthoDB" id="768508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032176">
        <property type="entry name" value="DUF5009"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16401">
        <property type="entry name" value="DUF5009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5009" evidence="2">
        <location>
            <begin position="13"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="378" mass="42092" checksum="60AD2DA19BA54351" modified="2008-04-29" version="1">MEATQAKTPKRRLMSLDALRGFDMFWILGGEALFAGLLLWTGWHGWQWADAQMHHSQWHGFTFYDLIFPLFIFLSGVALGLSPKRLDKLPMAQRMPLYKHSVKRLLLLLFFGVLYNHGWGTGAPVAIDEVRYASVLGRIAFAWFFAAMLVWHTSFRTQVLVTLGILVLYGLAQLLIPVPGYGAGIFSPEGSINAYVDTHLLPGIAYQNRALDPEGILSTLPAIVNAMAGVFVGHFIVKEHAKGEWYKVVTMLIAGALVLGCGWLLNLVIPVNKDLWTSSFVLVTTGWSMILLAVFYAAVDVLKWQKAAFPFVVIGCNAIIIYLASSLIDWKYTAQSLFGGLVSAFPSSAQELMAAISLLLVQWLVLFWMYKRGVFVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ49</accession>
    <name>B1KJ49_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2794</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2794"/>
    <dbReference type="EnsemblBacteria" id="ACA87069">
        <property type="protein sequence ID" value="ACA87069"/>
        <property type="gene ID" value="Swoo_2794"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2794"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_16_6"/>
    <dbReference type="OMA" id="HDQGELN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007891">
        <property type="entry name" value="CHASE3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05227">
        <property type="entry name" value="CHASE3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="470"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="467"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="717" mass="77682" checksum="C8B24F7646EB05AA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ98</accession>
    <name>B1KJ98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326897.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88570">
        <property type="protein sequence ID" value="ACA88570"/>
        <property type="gene ID" value="Swoo_4317"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4317"/>
    <dbReference type="eggNOG" id="ENOG50317WF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2304100_0_0_6"/>
    <dbReference type="OMA" id="RHDFSKT"/>
    <dbReference type="OrthoDB" id="2059612at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764955" evidence="1">
        <location>
            <begin position="23"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="101" mass="10938" checksum="75465810C57D434D" modified="2008-04-29" version="1" precursor="true">MKLLTSVTLSAVFVFASTSVLAEKPDFSKTTAAQASYDFSKNKPATGNQLMKSSTRHDFSKTAAASSEYQFSKNTPAKLYKVSLPSTQHDFSKTSSLKQGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJB9</accession>
    <name>B1KJB9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4338</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326917.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88591">
        <property type="protein sequence ID" value="ACA88591"/>
        <property type="gene ID" value="Swoo_4338"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4338"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026710_3_1_6"/>
    <dbReference type="OMA" id="ITVEHQR"/>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766705" description="Small-conductance mechanosensitive channel" evidence="8">
        <location>
            <begin position="23"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="533" mass="59160" checksum="EF6992350F42F1B2" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJE5</accession>
    <name>B1KJE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4364</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326943.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4364"/>
    <dbReference type="EnsemblBacteria" id="ACA88617">
        <property type="protein sequence ID" value="ACA88617"/>
        <property type="gene ID" value="Swoo_4364"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4364"/>
    <dbReference type="eggNOG" id="COG1115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024867_1_2_6"/>
    <dbReference type="OMA" id="ILMAPEY"/>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="459" mass="48170" checksum="1224D8DDA1D2ADA9" modified="2008-04-29" version="1">MERITDFVNMINGFVWGTPMLVMILGVGLFLSVGLKLMPILKLGTGFKLLWSGRIPDKDKNMKGEISPFNALMTSLSATIGTGNIAGVATAIFIGGPGALFWMWCTALVGMATKFSEAVLAVKFREVDDKGEHIGGPMYYIKNGLGSKWAWLGTAFALFGSFAGFGIGNTVQSNSVADALSSNFGVPTWITGVVLMLLVGAVLMGGIKRIADVAGKLVPLMSVFYIGAGIAVLIVNASEIPDAIALIVHSAFNPVAAQGGFAGAAVWAAIRFGVARGVFSNEAGLGSAPIAHASAQTNNPVAQGLVAMLGTFIDTLIVCSITGLAIIVTGSWTSGENGAALTSLAFSSAIPMGNYIVAIALSVFAFTTILGWSVYSEKCVQYLLGVKAVKPFRVLWILVVPLGAISSLDFIWLLADTLNAMMAIPNLIALALLSPVVFTLTREFFIKKREEDEKAKAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJE8</accession>
    <name>B1KJE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sodium:galactoside symporter (TC 2.A.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326946.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4367"/>
    <dbReference type="EnsemblBacteria" id="ACA88620">
        <property type="protein sequence ID" value="ACA88620"/>
        <property type="gene ID" value="Swoo_4367"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4367"/>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027408_6_0_6"/>
    <dbReference type="OMA" id="HQLAYGG"/>
    <dbReference type="OrthoDB" id="1249292at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="PTHR11328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="493" mass="54471" checksum="1317ECFD40DF60AC" modified="2008-04-29" version="1">MHSKEINKIAAEDRVPPIQKFIYGLGAFVNNLLGAAIGGMLIVLNLGLGMNPALVGLLGALPRLTDALTDPLMGYISDHSKTKWGRRRPFIFFGAIAAGLIFAMLWQVPREQSESFYFWFFLIGSVLFYLAYTVFATPWVALGYELTPDYHERTSLMAVQNFMGQIAWLTAPWFLWFMQSDLLFDDMIEGAGWLAIIIGGFTICVGILPAIFLKEPSKKPAKHTQITADTDEANTNSVDKKEANVEEFPAGVGDFFKGFLATIKFKPFLSLCGATFLVFNGFMMVSSFQTYVIIYYVFGGDQALGAEYAGWSGTVSAISTFCVIFIVTKLSASLGKRRAFYAVTGISIFGYALKWICYNPEHPLLLLIPPVFIAFGLGGLFTLMGSMIADVCDFDELKTRERREGMFGSIYWWVVKLGMAVALAAGGVLLNVTGFDVALGSAQTDDTIFLMRLFDVLIPIITSAIAIWLIMGYPITEAKANEVRQELEARKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJP7</accession>
    <name>B1KJP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1428"/>
    <dbReference type="EnsemblBacteria" id="ACA85720">
        <property type="protein sequence ID" value="ACA85720"/>
        <property type="gene ID" value="Swoo_1428"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1428"/>
    <dbReference type="eggNOG" id="COG2834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074356_2_0_6"/>
    <dbReference type="OMA" id="SWMGSDF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033399">
        <property type="entry name" value="Put_LolA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17131">
        <property type="entry name" value="LolA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766719" evidence="1">
        <location>
            <begin position="26"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="267" mass="30338" checksum="FBB11F0FD9B15BC2" modified="2008-04-29" version="1" precursor="true">MRMSLLNYVKLTLSFAIFLPVLSVAAVTKTDAGSELETRSAKEIVALSDKQMRGESSYTVATMNIIRPDWTRSMSMKSWTKGQDLSLVLVTAPAKDKGSASLKRKKEMWNWIPSIERVIKIAPSMLSQSWMGSDFTNDDLINQSSIVVDYTHTLVKEEMVDGDNSYVIDAFSKEDAPVVWSKVRLWISTKSYLQRRVEFYDEADALINTMETFDVKQLGGRLIATRMTMVPAEKPGNKTEMITHEAQFDFELGDDFFSQQQMRALRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJX7</accession>
    <name>B1KJX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325500.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87164">
        <property type="protein sequence ID" value="ACA87164"/>
        <property type="gene ID" value="Swoo_2889"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2889"/>
    <dbReference type="eggNOG" id="ENOG502ZUM1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2685804_0_0_6"/>
    <dbReference type="OMA" id="IYHEISA"/>
    <dbReference type="OrthoDB" id="1999438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="74" mass="8588" checksum="95A309A53EF535AC" modified="2008-04-29" version="1">MNALVEFEAGKLADLFDEGDSLNIHMFMDMMKMPYDVQDKLFFEISSLESLDRSKIEMIIESHGHSILNERLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF7</accession>
    <name>B1KKF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Conserved hypothetical cytosolic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1509</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324143.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1509"/>
    <dbReference type="EnsemblBacteria" id="ACA85797">
        <property type="protein sequence ID" value="ACA85797"/>
        <property type="gene ID" value="Swoo_1509"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1509"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030248_0_0_6"/>
    <dbReference type="OMA" id="FPYDPFI"/>
    <dbReference type="OrthoDB" id="193125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032295">
        <property type="entry name" value="DUF4842"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031025">
        <property type="entry name" value="LruC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16130">
        <property type="entry name" value="DUF4842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04456">
        <property type="entry name" value="LruC_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766764" evidence="2">
        <location>
            <begin position="24"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="4">
        <location>
            <begin position="355"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4842" evidence="3">
        <location>
            <begin position="479"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="714" mass="77657" checksum="AA57DCF2EF056EFC" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG2</accession>
    <name>B1KKG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324148.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1514"/>
    <dbReference type="EnsemblBacteria" id="ACA85802">
        <property type="protein sequence ID" value="ACA85802"/>
        <property type="gene ID" value="Swoo_1514"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1514"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059002_0_0_6"/>
    <dbReference type="OMA" id="GQVVQFI"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="42488" checksum="EA7A3ED3D5B1C13F" modified="2008-04-29" version="1">MKQAARILVVDDTAVSRLMLRGILEDKYDISEAESGEECLAIIDVSIPDLVLLDVDMPGMSGFEVCVALRREIVTAHLPIIFVSGLDTVEERLTGYEAGADEYITKPAEPEELHEKVGVCLSQHLEISHAKDSASEAMAIAMEAMTVSSELGQVVQFIKDVQSIERAEDVGLAMNNILLNFGMHAVSRVDTGDVVFVGCKKESIEAELLTRFVYHNERILSIGIRTIIRDPHIVLLIKDMPLDDEKRCGRLRDHLAVLMDIANVQLANLAARAKMLEQRQEIFTQVISMTEKQIQQTSERLITHEESSQGVMRGMLTELEGMLFGLGLEEDQEKQLIALADETSTKLEASQGQGELVNKELGAILECLYKFFNTLNESREQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKJ5</accession>
    <name>B1KKJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325548.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2939"/>
    <dbReference type="EnsemblBacteria" id="ACA87212">
        <property type="protein sequence ID" value="ACA87212"/>
        <property type="gene ID" value="Swoo_2939"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2939"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_2_0_6"/>
    <dbReference type="OMA" id="IELFEMH"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765006" evidence="1">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="25"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21628" checksum="3AE08F7B5B2E3918" modified="2008-04-29" version="1" precursor="true">MKYVLLVFTLLISVSANSAIPGMKGVQHFGFTVPNMQEAVDFFVDVMGCESYFSIGPFGPFNDNWMVDNLNVNKKAVIKVAHMVRCENGTNFEIFEYTSPDQNKKYVKNSDFGGNHIAFYVTDMDDAVAYLKEKDIKILGEPHTFTDTGMEGLTWVYFMAPWGQQLELVSYPDGQGYEKATNRRLWDPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKJ8</accession>
    <name>B1KKJ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2942</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325551.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2942"/>
    <dbReference type="EnsemblBacteria" id="ACA87215">
        <property type="protein sequence ID" value="ACA87215"/>
        <property type="gene ID" value="Swoo_2942"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2942"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047522_1_1_6"/>
    <dbReference type="OMA" id="HCERELA"/>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="257"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="40316" checksum="D43C2106F57B37F3" modified="2008-04-29" version="1">MKLGDISVSYIEIVIKAMLHLGINPDDILDKYSIDHKGLSSPDARVTIPKFMRLGHDCIEKSQAPWLGLVMGEVTTATNLGVAGLLALSSQDLKQACEQLATYELLNKYNSRGQSAFYVNHAFGMEMGKSRELCREYGIEDGQGVLMFYSINPYNEFNHFVVDSVLSGWYQVIKNLTGHEGAIEKVCFEFPAPEYADKYSEYFNCNVAFNQSNNYLVIKAQALDWACLNRSAPTFELLRRSADAELEKVRLGLSFHEKVSRVIGPLLDGTTPTLEQVSEQLNMAPWTVRRKLVEEGGSFQQTLNETRRTLSISYVRDTALTLGEIAYLLGFGSPTAFQRAFKRWTGEAPGRFRTSKSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR2</accession>
    <name>B1KKR2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325615.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3008"/>
    <dbReference type="EnsemblBacteria" id="ACA87279">
        <property type="protein sequence ID" value="ACA87279"/>
        <property type="gene ID" value="Swoo_3008"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3008"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_6"/>
    <dbReference type="OMA" id="YAYLSMQ"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="4">
        <location>
            <begin position="4"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="403" mass="42886" checksum="78FFA9FCA70F8310" modified="2008-04-29" version="1">MKRVVITGLGVVSSIGNNKQEVTESLKAGRSGITHSDQFEEMKLRSHVWGDIKLDPKEHIDRKALRFMGNAAAYAYIAMAEAIEDAGLTEEQYSDPRVGIIAGTGGASSANQVQAADTLREKGVKRVGPYIVPRIMSSTSSACLATPFKIKGMNYSISSACATSAHCIGHAVELIQMGKQDMVFAGGSEEVDWTLTMGFDAMGALSTKYNDTPEKASRTYDADRDGFVISGGGGIVVVEELEHALARGAKIYAEVVGYGASSDGYDMVAPSGEGAVRCMQMALADVNTPVDYINTHGTSTPVGDMRELEALRETFGENLPAIASTKSLTGHALGAAGAHEAIYSLIMMENNFIAPSINIDNLDEKAAGMPVVTEYREMELNTVMSNSFGFGGTNATLVMSKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL62</accession>
    <name>B1KL62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322752.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0102"/>
    <dbReference type="EnsemblBacteria" id="ACA84403">
        <property type="protein sequence ID" value="ACA84403"/>
        <property type="gene ID" value="Swoo_0102"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0102"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_6"/>
    <dbReference type="OMA" id="TITFAEC"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="33"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="25003" checksum="F21B4455F1E74272" modified="2008-04-29" version="1" precursor="true">MKRRDFITAGGIAVASALFAPHLFATPKGKPLKILALVFDDYETLDLHGPVEMLGHMSHVQILLVGAKSIIRSYQGPKVVTDISMEQVTPCDLLIVPGGIGTRTLVEDSELLSWLQAQEKVSKKVFSICTGSALLAKAGILDGVNATTNKMAYQWVTSLSQRVHWQPSARWVDEGKFLTSSGVSAGTDAALFYVRQLRGEEEARRIERLTEYHWNDDSTNDPYAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC3</accession>
    <name>B1KLC3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="1">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tadA</name>
        <name evidence="3" type="ordered locus">Swoo_1562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1562"/>
    <dbReference type="EnsemblBacteria" id="ACA85848">
        <property type="protein sequence ID" value="ACA85848"/>
        <property type="gene ID" value="Swoo_1562"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1562"/>
    <dbReference type="eggNOG" id="COG0590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025810_3_0_6"/>
    <dbReference type="OMA" id="PCQMCAG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14437">
        <property type="entry name" value="MafB19-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="18681" checksum="B996A7391A8EE793" modified="2008-04-29" version="1">MSQTERDIHYMKLAMDMAAKAEEKGEVPVGAILVKNDEVISAGFNFCIGSHDPSAHAEMQCLRQAGKVIENYRLLDTTLYVTLEPCAMCAGAMVHSRVSRLVFGASDAKTGAAGTVIDLVRHSAFNHQLEVTQGVLELECAEQLSQFFRRRRKEKKALKQQQKLSASPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLF1</accession>
    <name>B1KLF1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FlgO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324222.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1590"/>
    <dbReference type="EnsemblBacteria" id="ACA85876">
        <property type="protein sequence ID" value="ACA85876"/>
        <property type="gene ID" value="Swoo_1590"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1590"/>
    <dbReference type="eggNOG" id="COG5616">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1309412_0_0_6"/>
    <dbReference type="OMA" id="LTRDWQK"/>
    <dbReference type="OrthoDB" id="1956896at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014549">
        <property type="entry name" value="FlgO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041215">
        <property type="entry name" value="FlgO_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17680">
        <property type="entry name" value="FlgO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028688">
        <property type="entry name" value="UCP_imp_028688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767458" description="FlgO domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="FlgO" evidence="2">
        <location>
            <begin position="44"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="22533" checksum="BD4C9639F394BF0A" modified="2008-04-29" version="1" precursor="true">MRTLQLVLFTLLLSGCAQQVHTTKSPLADGNRLPSTSAINHVSQQIANELVRQNDALRANQPLLVATPVLLADLNQTNAVGLQLQEGLTAAMHDHQFSLVDINVGENIRVTPQGDFLLTRNWKQLPTGIAVEHVLVSTMSMSSEGMVINARVVNITNNRVVSASQASFGLEQLPGYLRASEQVVSQDGLLYRDSGMGEKEVRVIGGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLJ9</accession>
    <name>B1KLJ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1638</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324270.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1638"/>
    <dbReference type="EnsemblBacteria" id="ACA85924">
        <property type="protein sequence ID" value="ACA85924"/>
        <property type="gene ID" value="Swoo_1638"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1638"/>
    <dbReference type="eggNOG" id="COG0643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000650_3_7_6"/>
    <dbReference type="OMA" id="NELVECC"/>
    <dbReference type="OrthoDB" id="305000at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="8">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="382"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="7">
        <location>
            <begin position="595"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="134"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="205"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="733" mass="78717" checksum="C88B0DC726A26181" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP4</accession>
    <name>B1KLP4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325677.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3070"/>
    <dbReference type="EnsemblBacteria" id="ACA87341">
        <property type="protein sequence ID" value="ACA87341"/>
        <property type="gene ID" value="Swoo_3070"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3070"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_1_6"/>
    <dbReference type="OMA" id="EKCGFQL"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="20398" checksum="6BF76A3422E6302C" modified="2008-04-29" version="1">MLELYTDRLRLRTLRRDDMQDFLKVHQDPLINQYIAVPESETVLLEKFEHKLAPWHYDSGEWLTLSIEELGADRFIGFTGLYCSNLTLGHAEVGYMLATQGQGKGYASESLQAVIDWACLRFDVHKFIGTCAADNLASGRVLEKAGFKLEGVLRHNFKIKEQWIDDKVYGLLSEERSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS8</accession>
    <name>B1KLS8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325711.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3104"/>
    <dbReference type="EnsemblBacteria" id="ACA87375">
        <property type="protein sequence ID" value="ACA87375"/>
        <property type="gene ID" value="Swoo_3104"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3104"/>
    <dbReference type="eggNOG" id="COG4171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_5_3_6"/>
    <dbReference type="OMA" id="VPTYFRM"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="99"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="31666" checksum="44F6B75841D1BE6A" modified="2008-04-29" version="1">MPQIKIYQGDEIPSPMLKIWHTFADNPFAFAGLWAVVGFLLLAVFGPFIAPYSPEHQDPHALLLAPSWDPAGTVEHFLGTDDLGRDIFSRLLHGAHLTFGVALGIVLTSLVLGFIIGSISGMMKGLKSSILSHLLDALLSIPSLLMAILVVAVMGPGLNNVFWAVGIALTPQFVRAIHQAIHEELQKEYVKAAKLDGANPIQIFWYVIMPNVWDTVIIQTTLGISAAILDIAALGFLNLGAQAPSPEWGAMVSQGMDNILTAPWTVTIPGVAILCSVLAINLVGDGLRSALSPINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM08</accession>
    <name>B1KM08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4638</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327212.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88888">
        <property type="protein sequence ID" value="ACA88888"/>
        <property type="gene ID" value="Swoo_4638"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4638"/>
    <dbReference type="eggNOG" id="ENOG5031IAD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2669036_0_0_6"/>
    <dbReference type="OrthoDB" id="2082124at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="75" mass="7786" checksum="E52BD9678BE32597" modified="2008-04-29" version="1">MVVSLVSSFNAEVGSQKHSLQAIFSGTDTATFYKQRGSLTLVSLCSSLVANHMDVVNVINAGAIKDLASGPLNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM14</accession>
    <name>B1KM14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NMT1/THI5 like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327218.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4644"/>
    <dbReference type="EnsemblBacteria" id="ACA88894">
        <property type="protein sequence ID" value="ACA88894"/>
        <property type="gene ID" value="Swoo_4644"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4644"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_3_2_6"/>
    <dbReference type="OMA" id="AMTYEPY"/>
    <dbReference type="OrthoDB" id="785019at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766810" evidence="1">
        <location>
            <begin position="17"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="38"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="318" mass="35127" checksum="E268B3A7449A9490" modified="2008-04-29" version="1" precursor="true">MLRFTVSLFISLLLVACSPKPVTKTITIAINPWPGYELLYLAESKGFFKQVGLDIKLSQTATLSDAQRAYISGRVDGFASTIVEAVQAQEFGGDPLNIVLLADYSNGGDLIVSHEDFKTLNQLKGQKVGCEVSSLGIYILARALAVYDMSLDDVEIVNMEQGNALQALNSGHIDAMVTYPPYSFEILNSTSQKSHKVFTTAEIPNEILDTVSFSQNVIKANPDLVPKLQQAWQLAYDYLEQHPDEAIQLMAERELISVDEFSQSLADIYLLSNPEQNKLLKENKKLTNLAQSVCDTLNKVGAFDSSCEHIETLFYTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM46</accession>
    <name>B1KM46_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322808.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0158"/>
    <dbReference type="EnsemblBacteria" id="ACA84459">
        <property type="protein sequence ID" value="ACA84459"/>
        <property type="gene ID" value="Swoo_0158"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0158"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_323582_0_0_6"/>
    <dbReference type="OMA" id="LTDHHEM"/>
    <dbReference type="OrthoDB" id="96337at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766818" evidence="1">
        <location>
            <begin position="24"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="56"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="848" mass="95210" checksum="53CA9FA4C3CB71D9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM55</accession>
    <name>B1KM55_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322817.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0167"/>
    <dbReference type="EnsemblBacteria" id="ACA84468">
        <property type="protein sequence ID" value="ACA84468"/>
        <property type="gene ID" value="Swoo_0167"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0167"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_6"/>
    <dbReference type="OMA" id="MHFTKPF"/>
    <dbReference type="OrthoDB" id="1729688at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="12958" checksum="61BF54EE0E9DAE6F" modified="2008-04-29" version="1">MKKILAVDDSASMRQMVGFTLKTAGFDVTEACDGDEALKAAQGGEFDLVISDVNMPVMDGLTLIRNLRTLPAYKFTPLLMLTTESGVDKKHEGRSAGATGWIVKPFNPDQLLATVRKVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM72</accession>
    <name>B1KM72_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative permease of the major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322834.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0184"/>
    <dbReference type="EnsemblBacteria" id="ACA84485">
        <property type="protein sequence ID" value="ACA84485"/>
        <property type="gene ID" value="Swoo_0184"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0184"/>
    <dbReference type="eggNOG" id="ENOG5033YRA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166883_0_0_6"/>
    <dbReference type="OMA" id="INLRDTW"/>
    <dbReference type="OrthoDB" id="1740756at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="13349" checksum="0C20493F4837F58C" modified="2008-04-29" version="1">MSLLGMPFVDTGADTALHVVALVVMVVTVSAVAVGFWKIHEMPINKAHKEEHHQIGLITALTWIGFVWHWVWVLAVFVAFVDGEKALRKLRDIWHEQPDNSAQQSLEAPQSDREVTNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH9</accession>
    <name>B1KMH9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerol-3-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.39</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.39" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324323.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1692"/>
    <dbReference type="EnsemblBacteria" id="ACA85977">
        <property type="protein sequence ID" value="ACA85977"/>
        <property type="gene ID" value="Swoo_1692"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1692"/>
    <dbReference type="eggNOG" id="COG0615">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034585_2_2_6"/>
    <dbReference type="OMA" id="AFFNYQQ"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047348">
        <property type="term" value="F:glycerol-3-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019350">
        <property type="term" value="P:teichoic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006409">
        <property type="entry name" value="G3P_cytidylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01518">
        <property type="entry name" value="g3p_cytidyltrns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="15267" checksum="AA8884661118D250" modified="2008-04-29" version="1">MKTIITYGTFDLFHFGHVRLFQRLKAMGDRLIVCVSTDEFNAKKGKVAFFNYQQRAEIIAACRYVDLVLPETNWEQKREDIEKLDIDIFGMGSDWQGKFDDLSNQCKVVYLDRTGNISTTEIKSSLGANQGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMS7</accession>
    <name>B1KMS7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325791.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3184"/>
    <dbReference type="EnsemblBacteria" id="ACA87455">
        <property type="protein sequence ID" value="ACA87455"/>
        <property type="gene ID" value="Swoo_3184"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3184"/>
    <dbReference type="eggNOG" id="COG3287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052774_2_0_6"/>
    <dbReference type="OMA" id="CELHNQT"/>
    <dbReference type="OrthoDB" id="1942718at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019494">
        <property type="entry name" value="FIST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013702">
        <property type="entry name" value="FIST_domain_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08495">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10442">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00897">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01204">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FIST" evidence="1">
        <location>
            <begin position="25"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="FIST_C" evidence="2">
        <location>
            <begin position="218"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="377" mass="41114" checksum="764F7D4635C40182" modified="2008-04-29" version="1">MKTFQTQWHDNHWAQSDKIEDLDSKQTLILIFGEIHLQPDAIAKMKSLSPNACITGCSTAGEIQGRQVNDDSLIATIIAFEKTNITMIRGVDKPDINSKELGVNLANQLNETDNLCHVLVLSDGLGFNASHLIEGMTDILGLDIQVSGGLAGDRHNFVKTHLLFNDEVTSSAVIAIGFYGEQLEVSCGTRGGWCSFGIERRVTQAENNMLVELDDENALSIYKSYLGELAEQLPASGLRFPLEISEPNKITKVVRTLLAVDEETGTLTFAGNIPTGATAQLMRSNVESLIQGSLEAGKICRHNISSSPQVAILISCVGRKLVLKQLVEDEIEVISEELGEQALLCGFYSYGEIAPYDRGCLAELHNQTMTITAFAEI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX1</accession>
    <name>RL5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplE</name>
        <name type="ordered locus">Swoo_4678</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327251.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMX1"/>
    <dbReference type="SMR" id="B1KMX1"/>
    <dbReference type="STRING" id="392500.Swoo_4678"/>
    <dbReference type="EnsemblBacteria" id="ACA88928">
        <property type="protein sequence ID" value="ACA88928"/>
        <property type="gene ID" value="Swoo_4678"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4678"/>
    <dbReference type="eggNOG" id="COG0094">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061015_2_1_6"/>
    <dbReference type="OMA" id="ERMYAFL"/>
    <dbReference type="OrthoDB" id="1456375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142451" description="50S ribosomal protein L5">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <sequence length="179" mass="20375" checksum="B781C5B35D79EA40" modified="2008-04-29" version="1">MAKLHDKYQETVSPELQKKFGFTSVMQVPRIEKITLNMGVGEAVADKKVMEHALRDMTAIAGQKPVVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGMSTKSFDGRGNYAMGVREQIIFPEIQYDKIDKIRGMDIVITTSAKNDEEGRALLEAFNFPFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ5</accession>
    <name>B1KMZ5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusG</name>
        <name evidence="9" type="ordered locus">Swoo_4702</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327270.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4702"/>
    <dbReference type="EnsemblBacteria" id="ACA88952">
        <property type="protein sequence ID" value="ACA88952"/>
        <property type="gene ID" value="Swoo_4702"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4702"/>
    <dbReference type="eggNOG" id="COG0250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067287_1_0_6"/>
    <dbReference type="OMA" id="DGPFNGF"/>
    <dbReference type="OrthoDB" id="2027986at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015869">
        <property type="entry name" value="Transcrpt_antiterm_NusG_bac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01014">
        <property type="entry name" value="NUSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="8"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="21042" checksum="6E51822298F2ADEE" modified="2008-04-29" version="1">MTEATEAKKRWYVVQAFSGYEGRVTKTLHEYIQMHSMEQYFGEILVPTEEVVEMRAGQRRKSERKFFPGYVLVQMEMNDESWHLVKSIPRVMGFIGGTSDRPAPISDKEANAILQRLQETTETPTHRVIFEPGEVVRVTDGPFADFNGTVEEVDYEKNRVKVSVMIFGRSTPVELDFGQIEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN24</accession>
    <name>B1KN24_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system core protein G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4731</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP G family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327298.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4731"/>
    <dbReference type="EnsemblBacteria" id="ACA88981">
        <property type="protein sequence ID" value="ACA88981"/>
        <property type="gene ID" value="Swoo_4731"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4731"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091705_2_1_6"/>
    <dbReference type="OMA" id="PWRNDYL"/>
    <dbReference type="OrthoDB" id="2044924at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013545">
        <property type="entry name" value="T2SS_protein-GspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010054">
        <property type="entry name" value="Type2_sec_GspG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08334">
        <property type="entry name" value="T2SSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01710">
        <property type="entry name" value="typeII_sec_gspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSG" evidence="11">
        <location>
            <begin position="32"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="144" mass="16040" checksum="8AC0ADD42AD7D4AD" modified="2008-04-29" version="1">MQARKKQQGFTLLEVMVVIVILGILASMVVPNLMGNKDKADIQKAISDIVALENSLDMYKLDNSIYPTTEQGLEALTQKPTGSPEPRNYREDGYVKRLPQDPWRNDYLLLSPGENGKIDIFSAGPDGQAGTEDDIGNWNLQNFQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN30</accession>
    <name>HSLO_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">33 kDa chaperonin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Heat shock protein 33 homolog</fullName>
            <shortName evidence="1">HSP33</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hslO</name>
        <name type="ordered locus">Swoo_4737</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSP33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327304.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KN30"/>
    <dbReference type="SMR" id="B1KN30"/>
    <dbReference type="STRING" id="392500.Swoo_4737"/>
    <dbReference type="EnsemblBacteria" id="ACA88987">
        <property type="protein sequence ID" value="ACA88987"/>
        <property type="gene ID" value="Swoo_4737"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4737"/>
    <dbReference type="eggNOG" id="COG1281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054493_0_0_6"/>
    <dbReference type="OMA" id="DMQCECC"/>
    <dbReference type="OrthoDB" id="1406579at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00498">
        <property type="entry name" value="Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.30.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00117">
        <property type="entry name" value="HslO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000397">
        <property type="entry name" value="Heat_shock_Hsp33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016154">
        <property type="entry name" value="Heat_shock_Hsp33_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016153">
        <property type="entry name" value="Heat_shock_Hsp33_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023212">
        <property type="entry name" value="Hsp33_helix_hairpin_bin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30111">
        <property type="entry name" value="PTHR30111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01430">
        <property type="entry name" value="HSP33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005261">
        <property type="entry name" value="Heat_shock_Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118352">
        <property type="entry name" value="SSF118352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64397">
        <property type="entry name" value="SSF64397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0676">Redox-active center</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000095030" description="33 kDa chaperonin">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="1">
        <location>
            <begin position="225"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="1">
        <location>
            <begin position="258"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00117"/>
        </source>
    </evidence>
    <sequence length="286" mass="31601" checksum="1F31FF0899F8CA64" modified="2008-04-29" version="1">MSKDNLHRYLFENADVRGELVQLEQSYQEVLSAHNYPAPIQNLLGQLLAATSLLTATLKFNGDISVQLQGDGPVSLAVINGNNLQQLRGVARFKGELSSDGDLQQLFGKGHMVITLTPTEGERYQGVVALDKPTLAGCLEEYFAQSEQLPTSITLFANGKQAAGMLLQVLPTEGDHNAEFEHLEQLTATVKAEELFELEAEEVLHRLYHQEEVRLFEPVAVTFSCTCSRERSASAIRTVSREEIESILAEQGKIEMGCEYCNTNYSFDSIDVAAIFSNTQAPETKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN42</accession>
    <name>B1KN42_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88999">
        <property type="protein sequence ID" value="ACA88999"/>
        <property type="gene ID" value="Swoo_4750"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4750"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127592_1_0_6"/>
    <dbReference type="OMA" id="YELAVWT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767509" evidence="1">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="36"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="146" mass="16144" checksum="BD045C82E596F50F" modified="2008-04-29" version="1" precursor="true">MKHILALVLSLFIASTSANNLGEIKDETTEMTQHNKINYIEIPAKNIEATKAFFSEVFDWSFVDYGPDYCSFGGQGVDGGFFKSELVVSTQNGSPLIVLYSNSLEETQAKIEKSGGKTIKPIFSFPGGRRFHFSDPSGNEFAVWSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN46</accession>
    <name>B1KN46_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4754"/>
    <dbReference type="EnsemblBacteria" id="ACA89003">
        <property type="protein sequence ID" value="ACA89003"/>
        <property type="gene ID" value="Swoo_4754"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4754"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032905_0_0_6"/>
    <dbReference type="OMA" id="SNGADYQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764681" evidence="1">
        <location>
            <begin position="29"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="90"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="627" mass="70949" checksum="B2CF93B4A31F022B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN48</accession>
    <name>B1KN48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0244</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322894.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0244"/>
    <dbReference type="EnsemblBacteria" id="ACA84545">
        <property type="protein sequence ID" value="ACA84545"/>
        <property type="gene ID" value="Swoo_0244"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0244"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_18_0_6"/>
    <dbReference type="OMA" id="WWVGSRG"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="421" mass="44989" checksum="E91108FA6FB9763E" modified="2008-04-29" version="1">MNQIKGKIGRWQGAGLMATTLLGTGVFILPQMTIETAGSGALIAWLVLTLAIIPVTLVFGRLASVFPHAAGPAYFVEQAFGRTSGRTIGLLFLLVIPLGAPAAIMMTFKFVDVLVTLSGWAEVMTELLLLGVLAVLNFRGVQVSAKLQFALTLGVVSVVVALFGAGGLNLSEMESLTSAVKPEVALIMAAAGIAFWSFLGVEAMTHLANDFRDPKRDMIPAMMIGTLLVGLVYLACTLLLLLFPGTSNLAMVAVFDSLLGGYGAQVIGILGIASGLATVNVYTASAARLVWSFSREGVLPKYFELLNHYGAPVRASSVLLAVMAVVIVLTYITGQDLEGLIAWTNGVFVIIYLVSMLAAIKLLSRRFLPLVSLSCLLCLLLAFALGMNMAYALILTAILYPLLWWQKVHLLRRERAQVILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN53</accession>
    <name>B1KN53_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sel1 domain protein repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322899.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0249"/>
    <dbReference type="EnsemblBacteria" id="ACA84550">
        <property type="protein sequence ID" value="ACA84550"/>
        <property type="gene ID" value="Swoo_0249"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0249"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_555359_0_0_6"/>
    <dbReference type="OMA" id="RDLCYRA"/>
    <dbReference type="OrthoDB" id="1108212at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025285">
        <property type="entry name" value="DUF4145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13643">
        <property type="entry name" value="DUF4145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4145" evidence="1">
        <location>
            <begin position="24"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="471" mass="51823" checksum="7D290AA0A2EF32A2" modified="2008-04-29" version="1">MLTDVEFVAHFSPELGQDYRVAKSYVTDVPTQALLQIRSLTHKLTELLALPMGITFDSPNLYDRIETLNSRRVINVRVTRAMHKLRGDGNRGAHPEKYHLTSEQLQQLSEKSIERLLSLIESLFVQVTGKSLPKYHFEAFDSLAGRDLCYRAVMESDPQAQYLVGMSLKTRALMQREQELALGDEHDGKGSELGSSSETLKKAEYWFGLASTSEMDARYEYGVAKIHGYSGEPDVIAGEEAIAQAAAAGVVNAMALLGYFYLVGGKSLAVDRDKALDYLQRAADLEQSEAMANLGVLYYQEGALTQAYQFIAKAAQAGFPHAQYHLALMLARGEGCEVDPLGSEQWMAEAAELGQIDAMFSRAQSMLNDDNAFGTDLSQAELYLREVIKYGHSVPAMIELSIALADGVLGRIDVVGSASLLKLAREHGNEHELSVISPLWDSLSQQVENVIAVTKNKAELVALKRAQELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN83</accession>
    <name>B1KN83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322929.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84580">
        <property type="protein sequence ID" value="ACA84580"/>
        <property type="gene ID" value="Swoo_0279"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0279"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1288155_0_0_6"/>
    <dbReference type="OMA" id="LRGAMIN"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="26056" checksum="5411AF84167DCCE3" modified="2008-04-29" version="1">MSSWKQREQYLVQVAQRCLQGHKTFDLYRSHLVNASQISKGTIYNHFTTEADLILAVSCCEYEYWLGLAKQDLKEHQDPLTCFLYHHCNRLYYTLSEKRFVVDRVMPNQDLLNQANELLRLRFETLYEEYVSLNKRMILDIGEVAGFDRVELVMNYLRGAMINSDDADKHFGDVQLYYQFSYALSQLMGHSDRRIPTKLAFAAWLSAKHREKHQVTIINSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNJ3</accession>
    <name>B1KNJ3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-dihydrouridine(16) synthase</fullName>
            <ecNumber evidence="7">1.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">U16-specific dihydrouridine synthase</fullName>
            <shortName evidence="7">U16-specific Dus</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA-dihydrouridine synthase C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dusC</name>
        <name evidence="11" type="ordered locus">Swoo_1786</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = H(+) + NADH + uridine(16) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = H(+) + NADPH + uridine(16) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the Dus family. DusC subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324416.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1786"/>
    <dbReference type="EnsemblBacteria" id="ACA86070">
        <property type="protein sequence ID" value="ACA86070"/>
        <property type="gene ID" value="Swoo_1786"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1786"/>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_0_4_6"/>
    <dbReference type="OMA" id="YRPPAHW"/>
    <dbReference type="OrthoDB" id="1710586at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.225.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02043">
        <property type="entry name" value="DusC_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032886">
        <property type="entry name" value="DusC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042270">
        <property type="entry name" value="DusC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF26">
        <property type="entry name" value="PTHR11082:SF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 7 8" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="10">
        <location>
            <begin position="4"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 9">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="199"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="7">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="7">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="7">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="7">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="7">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="315" mass="35211" checksum="2E953658133D26AF" modified="2008-04-29" version="1">MRVILAPMEGVADAPMRSLLTSVGGYDLVISEFIRVVDQLLPEKVFYRLCAELAYGSKTKAGTPVRLQLLGQHPNWMAENAIRAIELGSLGVDLNYGCPAPMVNRSNGGAALLKEPETIYKVTKAVREAVPSSHPVSAKIRLGWDDKSRCVEIAQAIESAGATELTVHARTKEEGYRPPAHWEYINLIREAIAIPVIANGEVWCHQDYLKCQAASGCDDVMIGRGALAVPNLAHVIKTNQVKMPWNQVMQLLVQYSEYEIVSVKEKYYPARIKQWLKFMVKQYPQADTLFAQVRVMKQTQEILALLRSEAENQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPC5</accession>
    <name>B1KPC5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323044.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0396"/>
    <dbReference type="EnsemblBacteria" id="ACA84695">
        <property type="protein sequence ID" value="ACA84695"/>
        <property type="gene ID" value="Swoo_0396"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0396"/>
    <dbReference type="eggNOG" id="ENOG5033NWC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_911827_0_0_6"/>
    <dbReference type="OMA" id="IGECYKQ"/>
    <dbReference type="OrthoDB" id="1814045at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="273" mass="29752" checksum="2EFB9EB611652DF3" modified="2008-04-29" version="1">MKVILILLLVFLGVYLYMRAKRLAEKEQEVAKPVEKEIHESTAVEQKAAEEVSIVDVVDTSVADKVETVETVKADVSDEQKLDTANSEATQDEVAIAVALPDVDPAEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPVSVATDESWANAKLAGSLKEYRSSSDSAIQHSALLAAIGECYKQRKQAEYANYGAGLTPEYIEVFASLKSPTNEKGVGFMHLSTLLNDTGMFDKAIEVCQKAITYGLSDGTVTGFEGRISRIEKAKAKANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPG5</accession>
    <name>B1KPG5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Succinate dehydrogenase hydrophobic membrane anchor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Swoo_1834</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Membrane-anchoring subunit of succinate dehydrogenase (SDH).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="15">The heme is bound between the two transmembrane subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell inner membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324464.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1834"/>
    <dbReference type="EnsemblBacteria" id="ACA86118">
        <property type="protein sequence ID" value="ACA86118"/>
        <property type="gene ID" value="Swoo_1834"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1834"/>
    <dbReference type="eggNOG" id="COG2142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151315_2_0_6"/>
    <dbReference type="OMA" id="QWMKVLT"/>
    <dbReference type="OrthoDB" id="2048140at2"/>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014312">
        <property type="entry name" value="Succ_DH_anchor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38689">
        <property type="entry name" value="PTHR38689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000169">
        <property type="entry name" value="SDH_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02968">
        <property type="entry name" value="succ_dehyd_anc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 15" id="KW-0408">Iron</keyword>
    <keyword evidence="12 13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 13" id="KW-0813">Transport</keyword>
    <keyword evidence="13" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with second transmembrane subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000169-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000169-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA86118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12528" checksum="C7881532A0BA29E1" modified="2008-04-29" version="1">MVTNAASLGRSGVHDFILIRSSAVVLAIYTIFLVGFIACSSPLTYDAWHGLFSALPMKVFTLLALVAVLIHAWIGIWQVLTDYVKPLMLRGVLQFVFVVAAFSYLAAGILIVWGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ6</accession>
    <name>B1KPQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325925.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3320"/>
    <dbReference type="EnsemblBacteria" id="ACA87589">
        <property type="protein sequence ID" value="ACA87589"/>
        <property type="gene ID" value="Swoo_3320"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3320"/>
    <dbReference type="eggNOG" id="COG0659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_13_1_6"/>
    <dbReference type="OMA" id="VTNKFPI"/>
    <dbReference type="OrthoDB" id="751256at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="472"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="573" mass="61201" checksum="8016CE599AF86A72" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPY2</accession>
    <name>B1KPY2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Two component transcriptional regulator, LytTR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4846</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327412.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4846"/>
    <dbReference type="EnsemblBacteria" id="ACA89095">
        <property type="protein sequence ID" value="ACA89095"/>
        <property type="gene ID" value="Swoo_4846"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4846"/>
    <dbReference type="eggNOG" id="COG3279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_14_1_6"/>
    <dbReference type="OMA" id="ESDGNYS"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA89095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="28068" checksum="F2560EB3C9E37C6D" modified="2008-04-29" version="1">MLKVLIVDDEYLARLELTRLLSKYVDIEIVGEAEDGHQALELLKKTSVDLAFVDIQMPEMDGLEFAKQAESQQFQLVFCTAFSEHAVDAFELNAFDYIVKPIMPERLEAVLNKVRLIQETHDETEQDDIQCLPDNHGLLLKFGSDYKIVRINEICRFESLGNHVAVYSDSGKSYLHISLSKVEKKLDPAVFFKASRSDIVRVDQIDKIEEGMASGSLQVHMNNGQEIDVSRRQVQLLRKIFSIDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPY5</accession>
    <name>B1KPY5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4849</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327415.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4849"/>
    <dbReference type="EnsemblBacteria" id="ACA89098">
        <property type="protein sequence ID" value="ACA89098"/>
        <property type="gene ID" value="Swoo_4849"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4849"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="QVHKYYG"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="26180" checksum="90A5CD5DA652E62E" modified="2008-04-29" version="1">MHHSKPVIQLKGVTKTYQIGDEGYTALKGVDLSIHTNEFVAITGPSGSGKSTLMNILGCLSTPTTGAYQLNSQDVANYDEDKLAHVRNYSIGFIFQSFNLLPRQSILQNVIHPLKYRAMSSKERKSRALNALEKVGLGDKVKSLPSQLSGGQRQRVAIARALVTEPEILLGDEPTGNLDSKTTQEIMALFDQLHAQGQTIVLVTHEQDIAEHCQREIRLVDGLLASDVSKSKVEWGLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPZ6</accession>
    <name>B1KPZ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327426.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4860"/>
    <dbReference type="EnsemblBacteria" id="ACA89109">
        <property type="protein sequence ID" value="ACA89109"/>
        <property type="gene ID" value="Swoo_4860"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4860"/>
    <dbReference type="eggNOG" id="COG1022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_45_5_6"/>
    <dbReference type="OMA" id="GEGEKMP"/>
    <dbReference type="OrthoDB" id="164380at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="598" mass="67271" checksum="978725F4D5F3F7E3" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ66</accession>
    <name>YIDD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_4930</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ66"/>
    <dbReference type="STRING" id="392500.Swoo_4930"/>
    <dbReference type="EnsemblBacteria" id="ACA89179">
        <property type="protein sequence ID" value="ACA89179"/>
        <property type="gene ID" value="Swoo_4930"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4930"/>
    <dbReference type="eggNOG" id="COG0759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144811_5_2_6"/>
    <dbReference type="OMA" id="QPTCSHY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00386">
        <property type="entry name" value="UPF0161_YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00278">
        <property type="entry name" value="TIGR00278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000197781" description="Putative membrane protein insertion efficiency factor">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00386"/>
        </source>
    </evidence>
    <sequence length="85" mass="9507" checksum="BBD6807E23AE1E0F" modified="2008-04-29" version="1">MAKTQSPLQWLATTLIRGYQVFISPFLGANKCRFHPTCSTYAIEAIRLHGSVKGCWLAARRILKCHPLHPGGIDPVPPKTHRCNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ89</accession>
    <name>B1KQ89_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ilvA</name>
        <name evidence="13" type="ordered locus">Swoo_0446</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323093.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0446"/>
    <dbReference type="EnsemblBacteria" id="ACA84744">
        <property type="protein sequence ID" value="ACA84744"/>
        <property type="gene ID" value="Swoo_0446"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0446"/>
    <dbReference type="eggNOG" id="COG1171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_6_3_6"/>
    <dbReference type="OMA" id="VNFPQRA"/>
    <dbReference type="OrthoDB" id="1876944at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="338"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="433"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA84744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="516" mass="56535" checksum="1BDA224AEF4A7BE5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA4</accession>
    <name>B1KQA4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323108.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0461"/>
    <dbReference type="EnsemblBacteria" id="ACA84759">
        <property type="protein sequence ID" value="ACA84759"/>
        <property type="gene ID" value="Swoo_0461"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0461"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_0_3_6"/>
    <dbReference type="OMA" id="GPSKLHM"/>
    <dbReference type="OrthoDB" id="1534467at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="17879" checksum="A15FA5B8EE208DE3" modified="2008-04-29" version="1">MAELQLDKIDLAILKLLQGQGKLSNQELAEKVGLSASPCSRRVKAMEESGYIAGYATLLSAEHFNLSLTAYVQVRLEKHSQAILDSFEDKITQYDEVQECCLLTGSDADYQLKVLIADMKEFKTFLLEKLTTDPHISGVKSSFVLKQVKSKTSIPLPTQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQG4</accession>
    <name>B1KQG4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324549.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1919"/>
    <dbReference type="EnsemblBacteria" id="ACA86203">
        <property type="protein sequence ID" value="ACA86203"/>
        <property type="gene ID" value="Swoo_1919"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1919"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067698_2_0_6"/>
    <dbReference type="OMA" id="NPEWGVR"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010342">
        <property type="entry name" value="DUF938"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20974">
        <property type="entry name" value="PTHR20974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06080">
        <property type="entry name" value="DUF938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="202" mass="22991" checksum="310C8A493434AC85" modified="2008-04-29" version="1">MNINQLPFSQACENNKAPILDVIRPLFLNSTHLLEIGTGTAQHAVHFAQHLPHLIWQTSDQQGYLEGIEMRLAQVQLMNLRQPLALDVTQTWPLAKQANIDAMFTANTLHIMAKEMVKAFFNGVGEHLQSQGQLCIYGPFNYEGNYTSESNARFDIWLAEQNPQSAIRDIEWIIQLAKEQGLKLMADHTMPANNRLLHFIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI2</accession>
    <name>B1KQI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved hypothetical ABC transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324567.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1937"/>
    <dbReference type="EnsemblBacteria" id="ACA86221">
        <property type="protein sequence ID" value="ACA86221"/>
        <property type="gene ID" value="Swoo_1937"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1937"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064076_3_2_6"/>
    <dbReference type="OMA" id="FYPWNRA"/>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="23"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="241" mass="26694" checksum="D3F603E0ECC951B8" modified="2008-04-29" version="1">MGILASLLAPKVNAETLHLTSLHWPPYSSSQLAEQGAVIAITRAAVNAMGHKLEVDFYPWSRAVRLVNRKGAKYDGYLPAYPYPTEKFVFSDVLGTSPLGLVERRIHPVSWLEASDLNQYTLGVVRDYVNTSELDAMIKLGTQKVEVVNSDEHNLTKVATARVDAAVMDVNVLQFLLLQSKLKPLSSKVQVNKHILENKDLTIAFANNSQGLFWRDIVNAGLAKIDSDAMLSAYIKNSEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQP6</accession>
    <name>B1KQP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324631.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2001"/>
    <dbReference type="EnsemblBacteria" id="ACA86285">
        <property type="protein sequence ID" value="ACA86285"/>
        <property type="gene ID" value="Swoo_2001"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2001"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1077358_0_0_6"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="55"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="26602" checksum="332358ADA18BCF87" modified="2008-04-29" version="1">MFKIQDRKPRKAPFKDIDVARAYDLGMRKSALMSYQKPANRILEQAKDEMSDIVEVGVNTGLLSLYIGGKLPDTPVSGIEENKILLEVAEENLNLAVWSSNKGDIEFEGGKFHAMPFEDGSADIVFSFSSLHMWRNPIAVLKECKRICKHDGIVIIEDLNRAAEEGHITFVLQFIKDGGNEFIEALGSSYTPAESRKLLNEAGLEEWNVYQEDLGLIISSKPIDSLSSNLYTEDSNDN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR03</accession>
    <name>TATB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sec-independent protein translocase protein TatB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tatB</name>
        <name type="ordered locus">Swoo_0523</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TatB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323168.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KR03"/>
    <dbReference type="SMR" id="B1KR03"/>
    <dbReference type="STRING" id="392500.Swoo_0523"/>
    <dbReference type="EnsemblBacteria" id="ACA84820">
        <property type="protein sequence ID" value="ACA84820"/>
        <property type="gene ID" value="Swoo_0523"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0523"/>
    <dbReference type="eggNOG" id="COG1826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086034_1_0_6"/>
    <dbReference type="OMA" id="AKSMANN"/>
    <dbReference type="OrthoDB" id="2073616at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00237">
        <property type="entry name" value="TatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018448">
        <property type="entry name" value="TatB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01410">
        <property type="entry name" value="tatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0811">Translocation</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000100637" description="Sec-independent protein translocase protein TatB">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="132" mass="14429" checksum="ABF465C1A3C4C73F" modified="2008-04-29" version="1">MFDGIGFMELLLIGILGLVVLGPERLPVAVRSITGWIRAMKRMANSVKDELEQELKIEQLHSDLKKAENQGLKDLSPELQDSIDQLKEAAQSVNRPYKIEETPSASSSAPSESTPSEAPTAEVSANPDKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR58</accession>
    <name>B1KR58_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">YadA_anchor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0579</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323223.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0579"/>
    <dbReference type="EnsemblBacteria" id="ACA84875">
        <property type="protein sequence ID" value="ACA84875"/>
        <property type="gene ID" value="Swoo_0579"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0579"/>
    <dbReference type="eggNOG" id="ENOG5030IY9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_350178_0_0_6"/>
    <dbReference type="OrthoDB" id="2017099at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005594">
        <property type="entry name" value="YadA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03895">
        <property type="entry name" value="YadA_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764776" description="YadA_anchor domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_anchor" evidence="9">
        <location>
            <begin position="747"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="636"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="566"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="636"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="804" mass="84737" checksum="96B73CAE6DA2CDCA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR91</accession>
    <name>B1KR91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324644.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2014"/>
    <dbReference type="EnsemblBacteria" id="ACA86298">
        <property type="protein sequence ID" value="ACA86298"/>
        <property type="gene ID" value="Swoo_2014"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2014"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1276207_0_0_6"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="58"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="26641" checksum="58325753E4C5B7AE" modified="2008-04-29" version="1">MTQLMSNESRVPETDNGQQGEYIAEQYNLMQRDIRDHGWLNDKVELLINEGVVSGEILEVGMGPGYLGLEWLKMVGRKGHVTGLDIAADMVNVARRNSVEYGLEASTTYQVGDALKMPFEDESFNHVISYGSLHEWNMPMEVFKEIDRVIRPGGRYCVIDLRRDLDRQEISFMRMNIATDMRKGFMSSVKASYTRDELIKMLSGSVLEGAKIQNVPLALCVSGQKSHSKNSSKNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRS1</accession>
    <name>B1KRS1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="11" type="ordered locus">Swoo_3572</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326169.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3572"/>
    <dbReference type="EnsemblBacteria" id="ACA87836">
        <property type="protein sequence ID" value="ACA87836"/>
        <property type="gene ID" value="Swoo_3572"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3572"/>
    <dbReference type="eggNOG" id="COG0342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007894_4_3_6"/>
    <dbReference type="OMA" id="WKYVVLI"/>
    <dbReference type="OrthoDB" id="121331at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027398">
        <property type="entry name" value="SecD-TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13721">
        <property type="entry name" value="SecD-TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="535"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="SecD-TM1" evidence="10">
        <location>
            <begin position="10"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="604" mass="65899" checksum="C92FDCB8D7CB8ED3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRT1</accession>
    <name>DNAJ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dnaJ</name>
        <name type="ordered locus">Swoo_3582</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326179.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRT1"/>
    <dbReference type="SMR" id="B1KRT1"/>
    <dbReference type="STRING" id="392500.Swoo_3582"/>
    <dbReference type="EnsemblBacteria" id="ACA87846">
        <property type="protein sequence ID" value="ACA87846"/>
        <property type="gene ID" value="Swoo_3582"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3582"/>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_0_7_6"/>
    <dbReference type="OMA" id="DLHCTVT"/>
    <dbReference type="OrthoDB" id="1738789at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_1000137728" description="Chaperone protein DnaJ">
        <location>
            <begin position="1"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif">
        <location>
            <begin position="146"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif">
        <location>
            <begin position="163"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif">
        <location>
            <begin position="185"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif">
        <location>
            <begin position="199"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="1">
        <location>
            <begin position="133"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <sequence length="378" mass="40933" checksum="00761D834AD29418" modified="2008-04-29" version="1">MSKRDYYEVLSVGRDASEREIKKAYKRLAMKFHPDRNPGDKAAETSFKEVKEAYEILTDSDKKAAYDQFGHAGVDPNRGGGGFGGNADFGDVFGDVFGDIFGGGRRGGGQRQAARGSDLRYNLELSLEEAVKGLTKELRIPTLAHCDTCDGSGAKKGTSPTTCGTCHGQGQVQMRQGFFAVQQACPTCHGRGKIIKDPCNSCHGEGRVEKSKTLSVKIPAGVDNGDRIRLSGEGEAGEFGAPPGDLYVQVSVREHAIFVRDGNNLYCEVPISFGKAALGGEIEVPTLDGKVNLKIPAETQTGRMFRMRGKGVKSVRSHAVGDLLCKVVMETPVKLNERQKELLREFDETLAGSSSKKHSPKAEGFFDGVKKFFQDLNS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCY4</accession>
    <name>SYGB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="1">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="1">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glyS</name>
        <name type="ordered locus">Swoo_0012</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322662.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCY4"/>
    <dbReference type="SMR" id="B1KCY4"/>
    <dbReference type="STRING" id="392500.Swoo_0012"/>
    <dbReference type="EnsemblBacteria" id="ACA84313">
        <property type="protein sequence ID" value="ACA84313"/>
        <property type="gene ID" value="Swoo_0012"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0012"/>
    <dbReference type="eggNOG" id="COG0751">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007220_2_2_6"/>
    <dbReference type="OMA" id="LPIPKRM"/>
    <dbReference type="OrthoDB" id="213210at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="PTHR30075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01045">
        <property type="entry name" value="TRNASYNTHGB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000101339" description="Glycine--tRNA ligase beta subunit">
        <location>
            <begin position="1"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00255"/>
        </source>
    </evidence>
    <sequence length="689" mass="75751" checksum="665B937C11261BB4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD37</accession>
    <name>B1KD37_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">Bacterioferritin</fullName>
            <ecNumber evidence="5">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3608</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 7">Belongs to the bacterioferritin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326205.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3608"/>
    <dbReference type="EnsemblBacteria" id="ACA87872">
        <property type="protein sequence ID" value="ACA87872"/>
        <property type="gene ID" value="Swoo_3608"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3608"/>
    <dbReference type="eggNOG" id="COG2193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104506_2_0_6"/>
    <dbReference type="OMA" id="YQRLFHV"/>
    <dbReference type="OrthoDB" id="1890523at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00907">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002024">
        <property type="entry name" value="Bacterioferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002560">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00601">
        <property type="entry name" value="BACFERRITIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00754">
        <property type="entry name" value="bfr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00549">
        <property type="entry name" value="BACTERIOFERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0409">Iron storage</keyword>
    <keyword evidence="5 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="9">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="91"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002560-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="18317" checksum="85E4AED90912BD89" modified="2008-04-29" version="1">MKGQPKVLSQLNKVLTFELTAINQYFLHARMFKNWGLDALDKAAYKKSIQDMKHADKLIERVLFLEGLPNLQMLQKLRIGEQSEEMLACDKEMLEEQLVLMREAIEICESERDYVSRDILEDILEDEEEHLDWLEAQQELIGLTGIQNYLQSKMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD38</accession>
    <name>B1KD38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326206.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3609"/>
    <dbReference type="EnsemblBacteria" id="ACA87873">
        <property type="protein sequence ID" value="ACA87873"/>
        <property type="gene ID" value="Swoo_3609"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3609"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_3_6"/>
    <dbReference type="OMA" id="EMTAHRD"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="181"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="328" mass="37172" checksum="5A2856884C00415D" modified="2008-04-29" version="1">MPNEPEAVLESVVQMTGQRQLDSLAESLVSTVRQMVNAEQVEIFKIDNDLELEDAVENLTKQGFQVSYGALLECLRSRSTVRLSTQVFEQIAIPILLKDIVVMILWVTSDQLSEQDSQMLKGFSKVYENFLSIVIESETDPLTGLLNRKAFLPRLTKVAKLIKQEAIDCALDPASCDLSAKRYWLCIFDIDKFKVINDTFGHLYGDEILIDLVKVMKATFNELDSLFRFGGDEFVVILSKREKAEMLHLCESFSHKLSIHHGREVKVTISMGIIEINSIEEPSELLVKADKALYYIKETGRDRVGLYEDLVADGSIIPLKIEDDIELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA4</accession>
    <name>B1KDA4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Invasion gene expression up-regulator SirB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326272.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3677"/>
    <dbReference type="EnsemblBacteria" id="ACA87939">
        <property type="protein sequence ID" value="ACA87939"/>
        <property type="gene ID" value="Swoo_3677"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3677"/>
    <dbReference type="eggNOG" id="COG3094">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123860_2_0_6"/>
    <dbReference type="OMA" id="WVVYAAK"/>
    <dbReference type="OrthoDB" id="2035223at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007360">
        <property type="entry name" value="SirB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39594">
        <property type="entry name" value="PTHR39594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04247">
        <property type="entry name" value="SirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005610">
        <property type="entry name" value="SirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14682" checksum="B977D4FC930605DF" modified="2008-04-29" version="1">METLNNLYPAIKHLHLTLVAVSVLFFIVRFALHLRDSPIMQKKLVKIAPHVIDTFLLLSGLTLCFIIKQYPFVDPWLSEKLGAVVAYILLATIALKANRNKLFKTFAALGAIAWVVYAAKLAMFKQAMLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDC1</accession>
    <name>B1KDC1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323269.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0626"/>
    <dbReference type="EnsemblBacteria" id="ACA84922">
        <property type="protein sequence ID" value="ACA84922"/>
        <property type="gene ID" value="Swoo_0626"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0626"/>
    <dbReference type="eggNOG" id="COG0412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_9_1_6"/>
    <dbReference type="OMA" id="IDFIIGC"/>
    <dbReference type="OrthoDB" id="1889569at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="3"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="22890" checksum="E270171820A51054" modified="2008-04-29" version="1">MKVILITDIFGVTEHLLQIQQGIAGAGWVCEVLDPYCGVDRQFTSEPVAYESFMAECGHKQYCDSVISKLDTADCPCVVIGFSAGASAAWKALDRLSPDSVSQLIGFYPSQIRHHLAVNPSVPVSLVFPAFEAHFDLDAVMASLAKKSLLMLSQTQYEHGFINFYSSAYYKLASSQYIDLLCNPKLLKDPNSMQLELARLSNKILDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF3</accession>
    <name>B1KDF3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1338 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323301.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0658"/>
    <dbReference type="EnsemblBacteria" id="ACA84954">
        <property type="protein sequence ID" value="ACA84954"/>
        <property type="gene ID" value="Swoo_0658"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0658"/>
    <dbReference type="eggNOG" id="COG5383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053061_1_1_6"/>
    <dbReference type="OMA" id="VAKHFEH"/>
    <dbReference type="OrthoDB" id="714422at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009770">
        <property type="entry name" value="DUF1338"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07063">
        <property type="entry name" value="DUF1338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01150">
        <property type="entry name" value="DUF1338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1338" evidence="1">
        <location>
            <begin position="5"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="265" mass="29566" checksum="C726F697DB5B85E4" modified="2008-04-29" version="1">MHTDINKLFESLWSDYLAMTPSAGKVHQLLSQGETIINDHIALRTFNIEKVNLAVLAAHFESLGYVDSGDYHFEAKKLKAKHFEHPDPTQPKVFISELMVEEFSPQLQSILKGLVDQIDVAATTADNFLYSGRHWELDFTTYETLLAESEYAAWVAAFGYRANHFTVSINHLPGYSTILDVNETLKKGDFILNSAGGEVKGSADVLLEQSSTMADKIEVDFKDVQKSIPSCFYEFALRYPKADGELYTGFVAASADKIFESTNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDR4</accession>
    <name>B1KDR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324805.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2179"/>
    <dbReference type="EnsemblBacteria" id="ACA86461">
        <property type="protein sequence ID" value="ACA86461"/>
        <property type="gene ID" value="Swoo_2179"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2179"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_2_6"/>
    <dbReference type="OMA" id="SVIKLDF"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="48"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="361" mass="39954" checksum="A00F93BDF99296B7" modified="2008-04-29" version="1" precursor="true">MKKIIITLILISLAFLAYQKLYPANETLVKKPRPIANVVVAKAAIEPIRDEVEALGTSKANESVTVTPKVTEVATALFFDDGDVVKKGQQLVQLQDREQLARVTAAKVRVNEHMRELDRIRSLVTNQTIAELERDRLQTLIDTAKAELAQASSALNDRQISAPFEGRLGLRQISVGSLLSPGTVITTLDDISVIKLDFSVPERFLPSLAVGKNVEATAMAFPDELFSGKVISIDSRVNPTTRAVIVRAELPNPKHRLLPGMLMKVKLIKESRDALILPESAIIPIQDRHYVYLVDGDDKVVKREVHLGLRKRGWVEILDGINLGEQVVIRGILKVRPGDKVKVQFSEKFSFLENAKVGPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX4</accession>
    <name>B1KDX4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">[Ribosomal protein S18]-alanine N-acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.266</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acetylates the N-terminal alanine of ribosomal protein S18.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + N-terminal L-alanyl-[ribosomal protein bS18] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18]</text>
            <dbReference type="Rhea" id="RHEA:43756"/>
            <dbReference type="Rhea" id="RHEA-COMP:10676"/>
            <dbReference type="Rhea" id="RHEA-COMP:10677"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64718"/>
            <dbReference type="ChEBI" id="CHEBI:83683"/>
            <dbReference type="EC" id="2.3.1.266"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. RimI subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.266" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3716"/>
    <dbReference type="EnsemblBacteria" id="ACA87976">
        <property type="protein sequence ID" value="ACA87976"/>
        <property type="gene ID" value="Swoo_3716"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3716"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_23_2_6"/>
    <dbReference type="OMA" id="ATLMDIC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006474">
        <property type="term" value="P:N-terminal protein amino acid acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006464">
        <property type="entry name" value="AcTrfase_RimI/Ard1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01575">
        <property type="entry name" value="rimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="151" mass="16712" checksum="4AF03AABAAC54904" modified="2008-04-29" version="1">MSFSTEPHIVTLNIDNAPEMAYIASQAHSHPMSLSTIESCFGHLYQSFGIYLADELQGFAIVHQVFEDATLMDICISPKSQGRGFGRLLLESVIESANEKGAETLFLEVRKSGLAAISLYKREGFKETGHRKGYYKTADGNEDAILMKLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDZ5</accession>
    <name>B1KDZ5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein TonB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_3738</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell inner membrane</location>
            <topology evidence="1 9">Single-pass membrane protein</topology>
            <orientation evidence="1 9">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TonB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326329.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3738"/>
    <dbReference type="EnsemblBacteria" id="ACA87997">
        <property type="protein sequence ID" value="ACA87997"/>
        <property type="gene ID" value="Swoo_3738"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3738"/>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055288_0_0_6"/>
    <dbReference type="OMA" id="PLMHLAW"/>
    <dbReference type="OrthoDB" id="1184688at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031992">
        <property type="term" value="F:energy transducer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003538">
        <property type="entry name" value="TonB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01374">
        <property type="entry name" value="TONBPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="11">
        <location>
            <begin position="14"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="316"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="45627" checksum="CBBCF39BE756FC70" modified="2008-04-29" version="1">MLNWLMEQTILISLICAILLVGHKQILKLFGAHHTYALWLAIPMLLLGSAIIHLVPNLLSNSRITQLEHYRVLADRTLADSELFLSTPTLLAIWTLGFAFMLMTIAVHAVRLKQLINHCSAFTSIETHLTVIQHQNIHSPMLVGLRKPKIIVPYGFEQLSIAQQTAVIEHELYHHRRGDIGMNLIAFSLLSIFWFNPICWLAYRRFRDDQELACDAQITTSMNTDEKIAYSRALLTYSQQAHIGMLHTHYGNKNILKERILQMKKQHEKSTLAIIGLTLGLGFSGLMLNQQVQAGDNHDSTHAAKKQQIYPLTRVEPKYPKAAIEAKQNGFVQLEFDIKKSGAVANVSVIKSSPKDVFDKQAVKALKQWTYKKSKQGAKGVQVQLDFVIDEPAADVERIKVTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE78</accession>
    <name>B1KE78_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Bifunctional protein HldE</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">D-beta-D-heptose 7-phosphate kinase</fullName>
                <ecNumber evidence="12">2.7.1.167</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">D-beta-D-heptose 7-phosphotransferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="12">D-glycero-beta-D-manno-heptose-7-phosphate kinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">D-beta-D-heptose 1-phosphate adenylyltransferase</fullName>
                <ecNumber evidence="12">2.7.7.70</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="primary">hldE</name>
        <name evidence="15" type="ordered locus">Swoo_0769</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.</text>
    </comment>
    <comment type="function">
        <text evidence="2 12">Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) = ADP-D-glycero-beta-D-manno-heptose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59967"/>
            <dbReference type="ChEBI" id="CHEBI:61593"/>
            <dbReference type="EC" id="2.7.7.70"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + D-glycero-beta-D-manno-heptose 7-phosphate = ADP + D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27473"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="ChEBI" id="CHEBI:60208"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.167"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Nucleotide-sugar biosynthesis; ADP-L-glycero-beta-D-manno-heptose biosynthesis; ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Nucleotide-sugar biosynthesis; ADP-L-glycero-beta-D-manno-heptose biosynthesis; ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">In the C-terminal section; belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">In the N-terminal section; belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.167" evidence="12"/>
    <dbReference type="EC" id="2.7.7.70" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0769"/>
    <dbReference type="EnsemblBacteria" id="ACA85064">
        <property type="protein sequence ID" value="ACA85064"/>
        <property type="gene ID" value="Swoo_0769"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0769"/>
    <dbReference type="eggNOG" id="COG0615">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2870">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021150_2_1_6"/>
    <dbReference type="OMA" id="CEFANAA"/>
    <dbReference type="UniPathway" id="UPA00356">
        <property type="reaction ID" value="UER00437"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033785">
        <property type="term" value="F:heptose 7-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033786">
        <property type="term" value="F:heptose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097171">
        <property type="term" value="P:ADP-L-glycero-beta-D-manno-heptose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01172">
        <property type="entry name" value="RfaE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01603">
        <property type="entry name" value="HldE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023030">
        <property type="entry name" value="Bifunc_HldE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011913">
        <property type="entry name" value="RfaE_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011914">
        <property type="entry name" value="RfaE_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02198">
        <property type="entry name" value="rfaE_dom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02199">
        <property type="entry name" value="rfaE_dom_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="13">
        <location>
            <begin position="14"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="CTP_transf_like" evidence="14">
        <location>
            <begin position="349"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribokinase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cytidylyltransferase" evidence="12">
        <location>
            <begin position="348"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA85064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="479" mass="50941" checksum="2D998D0C16D7011E" modified="2008-04-29" version="1">MSVMKVSLPAFEKAKVLVVGDVMLDRYWTGPTGRISPEAPVPVVQIKQIEDRPGGAANVALNVATLGGQVCLAGIVGKDETAEALTQGIQALGVEPKWHCVEDKPTITKLRVMSRNQQLIRLDFEEAYPVEESVSLFQKSEALLDNVGVVVLSDYAKGAVTDPQAFIKLAKSKGVKVLVDPKGSDFSRYRGASLLTPNMSEFEGVVGAVSSEADLVAKAQTLLANFEIEAILVTRSEKGMTLITSEGPELHIPTVAREVYDVTGAGDTVISALATALAAGSELPQACAIANTAAGIVVAKLGTSTVSRIELIEALSLNQGESGFGSVSEDQLVYALEQAKLRGERVVMTNGCFDILHAGHVSYLKQAKALGDRLIVAVNDDESVRRLKGDGRPVNQVDRRMSVLAGLASVDWVVPFTEDTPQRIISRLLPDMLVKGGDYKIEEIAGGEEVIASGGTVMVLGFEDGISTTKIIENIMANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE79</accession>
    <name>B1KE79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323412.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0770"/>
    <dbReference type="EnsemblBacteria" id="ACA85065">
        <property type="protein sequence ID" value="ACA85065"/>
        <property type="gene ID" value="Swoo_0770"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0770"/>
    <dbReference type="eggNOG" id="ENOG502ZVC8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1004350_0_0_6"/>
    <dbReference type="OMA" id="WLVQNSM"/>
    <dbReference type="OrthoDB" id="1445151at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="283" mass="32478" checksum="AD4E2AF8F3509D20" modified="2008-04-29" version="1">MIWTALALTTGLYLTQVNDKQVLLCETELLQPCLQELSPNARRQLPAIAADVNTLLGVRGAMVLPLQDTDTAGVILLDREQLPYSLSIELSGSLHSFTLAQQLKVTLLHEIGHLEAIALLESGAIDALSPYRHEWIADCYLIWRLAKEDKGLGLAWQQYHRRNVNMMQNVENISHWTVPIMAQVFNRYDVEQLVKFDSFNEFMQDALPRLSEESQDSLDEFASLFHRTFSTQVMHFLPDYMFWRKPVLGQLLEPTLVTLLGEHAAREWMKNQKLPSKMSLQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE92</accession>
    <name>B1KE92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323425.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0783"/>
    <dbReference type="EnsemblBacteria" id="ACA85078">
        <property type="protein sequence ID" value="ACA85078"/>
        <property type="gene ID" value="Swoo_0783"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0783"/>
    <dbReference type="eggNOG" id="ENOG5031GTU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2002356_0_0_6"/>
    <dbReference type="OMA" id="EYKMSSP"/>
    <dbReference type="OrthoDB" id="2195383at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="13691" checksum="1E479E83EF87E957" modified="2008-04-29" version="1">MSSPIGGFYLNAQYRKQADQFELDNKLKLELTIKLELDGKCLIEAAKSSLSDSALLLDNEQVTITLTPSVISETLIQIHSEIIIKQFDPIKTLQQQLTIESGEQLSTLVEGEPHLQLTLGGVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE99</accession>
    <name>B1KE99_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323432.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0790"/>
    <dbReference type="EnsemblBacteria" id="ACA85085">
        <property type="protein sequence ID" value="ACA85085"/>
        <property type="gene ID" value="Swoo_0790"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0790"/>
    <dbReference type="eggNOG" id="COG3074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041653_1_0_6"/>
    <dbReference type="OMA" id="IVTEFGY"/>
    <dbReference type="OrthoDB" id="801081at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764754" evidence="2">
        <location>
            <begin position="23"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="461" mass="51161" checksum="C90E135C59745DBF" modified="2008-04-29" version="1" precursor="true">MKTKLSLLAICVAGFNSHYAFAAPDPVKLQQAIAKQELELKQLKKDLAELAAQQNVQREEQKKQAKVIEVAKQEATESKFSKFSFKSYGSVNYTSDEYYQNVQDTTPERRGRFDLERIVTEFGYQFNDEWDMEVEIEYEHGGTGAALEYDGFDEFGEFESEIEAGGEVMIEKAQLRYRPSDAFGVKFGNIHLPIGLSSILHKPDQYLTVLRHRSEAAVLPAVWNETGVGVFGEVANFHYQAQVVSGLNSEYFRTYDWVASGHQKRFEHVNADDLAYAVRLDYGSFKEGSAIGVAYYYGNTSGNRHKSNKVSGDGTVSILALSGAYVQGPWILRGQYLNGTLSDSDAITQANKTTPGLKPGNFAQLGSKSEAFFVEAGFDLTDFTSIPLTVFANIDYSNPLAEVETGTATKRYENTWTSVGVNYFPIPEIVIKAEAGRQQVAVAAIPDTNFFALGVGYQFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB9</accession>
    <name>B1KEB9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="6">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324841.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2215"/>
    <dbReference type="EnsemblBacteria" id="ACA86497">
        <property type="protein sequence ID" value="ACA86497"/>
        <property type="gene ID" value="Swoo_2215"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2215"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_21_0_6"/>
    <dbReference type="OMA" id="PNMARHR"/>
    <dbReference type="OrthoDB" id="325071at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="618"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="940"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1110" mass="125352" checksum="EA3A5773DBFDFDF6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-11-16" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEH7</accession>
    <name>SEQA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Negative modulator of initiation of replication</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">seqA</name>
        <name type="ordered locus">Swoo_2274</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Polymerizes to form helical filaments.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SeqA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324898.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KEH7"/>
    <dbReference type="SMR" id="B1KEH7"/>
    <dbReference type="STRING" id="392500.Swoo_2274"/>
    <dbReference type="EnsemblBacteria" id="ACA86555">
        <property type="protein sequence ID" value="ACA86555"/>
        <property type="gene ID" value="Swoo_2274"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2274"/>
    <dbReference type="eggNOG" id="COG3057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099733_0_0_6"/>
    <dbReference type="OMA" id="RTRTYFA"/>
    <dbReference type="OrthoDB" id="1625515at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032297">
        <property type="term" value="P:negative regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00908">
        <property type="entry name" value="SeqA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005621">
        <property type="entry name" value="SeqA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026577">
        <property type="entry name" value="SeqA_DNA-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036835">
        <property type="entry name" value="SeqA_DNA-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033761">
        <property type="entry name" value="SeqA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03925">
        <property type="entry name" value="SeqA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17206">
        <property type="entry name" value="SeqA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019401">
        <property type="entry name" value="SeqA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82808">
        <property type="entry name" value="SSF82808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0236">DNA replication inhibitor</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000413940" description="Negative modulator of initiation of replication">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="1">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00908"/>
        </source>
    </evidence>
    <sequence length="179" mass="20073" checksum="5AB199316631318B" modified="2008-04-29" version="1">MKYIEVDEELYRLIASKTERIGESASEILRRLLGLEVEASATQEKDEPEVISQPGLEETADVEDKPRFIDLHSSINKEELAAAKGAVGRFLFILEAVYLASPEQFAQVLKIKGRDRLYFATSKQSLLKASKSANPKEIGQSGYWVTTNNNTAKKRTILTEVLHQYGTVEAQIESITRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI5</accession>
    <name>B1KEI5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2282</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324906.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2282"/>
    <dbReference type="EnsemblBacteria" id="ACA86563">
        <property type="protein sequence ID" value="ACA86563"/>
        <property type="gene ID" value="Swoo_2282"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2282"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="NHEAKAG"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010910">
        <property type="entry name" value="Nitrate/nitrite_sensing_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50906">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="NIT" evidence="7">
        <location>
            <begin position="55"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="333"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="391"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="664" mass="72566" checksum="562626CECDCBA2C5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW9</accession>
    <name>B1KEW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323467.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0825"/>
    <dbReference type="EnsemblBacteria" id="ACA85120">
        <property type="protein sequence ID" value="ACA85120"/>
        <property type="gene ID" value="Swoo_0825"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0825"/>
    <dbReference type="eggNOG" id="COG4941">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035311_1_0_6"/>
    <dbReference type="OMA" id="RYEDTDW"/>
    <dbReference type="OrthoDB" id="1469807at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="422" mass="47760" checksum="D81C8C196AA16718" modified="2008-04-29" version="1">MIELISEQLEKLVREDRGRIMATLMAQFGDLDRCEEAFQDAQALAMRAWCRGIPDNARAWILTTARRRAIDDIRREQCFQHVVSGLGEELSSELSLPTSEEELDEISLPDERLKLLLICCHPALEEKTSVVLSLRFIAGLTTIEIARAFLDKPATIGQRITRAKSKIRLSGIRYGLPTHEQLDGRIAAVLKVIYFIFNEGYACQQGDEQLRLDLCEEALFLAELVSQLQPNNAEVQGLLALMQLSYARSTARQSAEGLFIPLAQQNRDLWDRGLIANACERLERALELGQLGPYQLQASIGAIHCEAKAFSCTDWPQIVMMYRLLFKCQTNDVVLLNLFVAESYIYGAEYGLHKIEPLSRSLSAYQPFHAARAELLSKLTRFDEAVKAYGQASALTSVVSEKRYLQMQKEQVLRRKEESKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF22</accession>
    <name>B1KF22_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fructose-1,6-bisphosphate aldolase</fullName>
            <shortName evidence="8">FBP aldolase</shortName>
            <ecNumber evidence="8">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0879</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323520.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0879"/>
    <dbReference type="EnsemblBacteria" id="ACA85173">
        <property type="protein sequence ID" value="ACA85173"/>
        <property type="gene ID" value="Swoo_0879"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0879"/>
    <dbReference type="eggNOG" id="COG0191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040088_0_0_6"/>
    <dbReference type="OMA" id="PRTWGKL"/>
    <dbReference type="OrthoDB" id="827430at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006412">
        <property type="entry name" value="Fruct_bisP_Calv"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01521">
        <property type="entry name" value="FruBisAldo_II_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="6">
        <location>
            <begin position="233"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="6">
        <location>
            <begin position="275"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="38351" checksum="20F165B461883777" modified="2008-04-29" version="1">MALISLRQMLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMAAALEQYPDIPVCIHQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEYNVDVTRKTVAFAHACGVSVEGEIGCLGSLETGEAGEEDGIGAAGILSMDQMLTTPEEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQEWLEVINQYGGAIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAENPTEFDPRKFLKASMEAMADICTTRYEAFGCAGMGSKIKPKSLQAMYKAYQSGELDPQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF40</accession>
    <name>B1KF40_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0897</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323538.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0897"/>
    <dbReference type="EnsemblBacteria" id="ACA85191">
        <property type="protein sequence ID" value="ACA85191"/>
        <property type="gene ID" value="Swoo_0897"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0897"/>
    <dbReference type="eggNOG" id="COG0608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009736_5_1_6"/>
    <dbReference type="OMA" id="FIICDHH"/>
    <dbReference type="OrthoDB" id="491634at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="7">
        <location>
            <begin position="71"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="8">
        <location>
            <begin position="319"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="9">
        <location>
            <begin position="466"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="574" mass="63205" checksum="163238061030082F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF66</accession>
    <name>B1KF66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324949.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2328"/>
    <dbReference type="EnsemblBacteria" id="ACA86607">
        <property type="protein sequence ID" value="ACA86607"/>
        <property type="gene ID" value="Swoo_2328"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2328"/>
    <dbReference type="HOGENOM" id="CLU_2425296_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="91" mass="10595" checksum="A0F81E48467D670F" modified="2008-04-29" version="1">MVSDNRYVYLLMLIVVQRQKLSTTEGEHNGSYKLANERYEVELALRKGYRYRDHGEKPKEWIPEQVRDDGSGKCSILHVFALSFTVSEAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF83</accession>
    <name>B1KF83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine aldolase</fullName>
            <ecNumber evidence="6">4.1.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2345</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.5" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324966.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2345"/>
    <dbReference type="EnsemblBacteria" id="ACA86624">
        <property type="protein sequence ID" value="ACA86624"/>
        <property type="gene ID" value="Swoo_2345"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2345"/>
    <dbReference type="eggNOG" id="COG2008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029381_0_3_6"/>
    <dbReference type="OMA" id="ENTHNVC"/>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004793">
        <property type="term" value="F:threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="6"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="35977" checksum="1758AA0248208B24" modified="2008-04-29" version="1">MAGVIDLRSDTVTQPCQVMRTLMVEAQTGDDVYGEDPSVKQLESFAAELLNKQAAVFCPSGTQSNLMGLLSHCGRGDEFIVGSAAHTYLYEGGGAAVLGSIQPQPLNLQSDATMDLSELESAIKPKDVHYARTKLICLENTHGGVPLPDGYTQAVNAIAQRHKLGMHLDGARLFNAVVAGNTSAAALTADFDSVSICLSKGLGAPVGSLLVGSNEFIDEARHWRKMLGGGMRQAGIIAAAGLYALQNNINRLSDDHRRASELASALGQIDGVSIPLGQAHTNMLYVSVSQAMRQRLAEHEANYNILLPSGEQMRLVTHLNINDDDLKAIIELFQQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC2</accession>
    <name>B1KFC2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325005.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2384"/>
    <dbReference type="EnsemblBacteria" id="ACA86663">
        <property type="protein sequence ID" value="ACA86663"/>
        <property type="gene ID" value="Swoo_2384"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2384"/>
    <dbReference type="eggNOG" id="COG2334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049945_0_0_6"/>
    <dbReference type="OMA" id="CGMKDVI"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK" evidence="1">
        <location>
            <begin position="121"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="335" mass="38320" checksum="797BFBB37281A010" modified="2008-04-29" version="1">MNTQSEIIEYIQEQFSCSKVIKLEKIQTLWSGYGEISRYQVMVQDGAKNIIVKSIVPPNVPTHPKGWQGDVSHLRKIKSYQVEANWYQDYASTLSRASQVPHCFGVKSFAIDHPRHESSIILLSDLDASGFSVRKQHLSVDESKVCIKWLAIFHANNLQDNHLASWPKGLWATGSYWYLATRQNEYHAMQESNVKSAAYKLDDKLNRCRFKTIIHGDAKVANFCFSADLSKVAAVDFQYVGAGCGMKDLVYFMGSCLSEHDCQESYEELLEYYFSQLSAALQSRLDSCEIIEEWRPLFFVAWADFQRFLLGWSPEHHKINDFSSAITQRGISLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI3</accession>
    <name>B1KFI3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326488.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3900"/>
    <dbReference type="EnsemblBacteria" id="ACA88158">
        <property type="protein sequence ID" value="ACA88158"/>
        <property type="gene ID" value="Swoo_3900"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3900"/>
    <dbReference type="eggNOG" id="COG0123">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007727_1_0_6"/>
    <dbReference type="OMA" id="RVFTFSM"/>
    <dbReference type="OrthoDB" id="1443295at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016575">
        <property type="term" value="P:histone deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09993">
        <property type="entry name" value="HDAC_classIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044150">
        <property type="entry name" value="HDAC_classIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="42"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="34302" checksum="69DBCFFCFF494FED" modified="2008-04-29" version="1">MLPLIYHPMYSHLSLPEGHRYPIMKYQYLYDFIIKKSETDSNWQQRLAFFSPKALTADEVKQVHGDEYVEQLMTGTLAANKMRRIGFPWSEELMQRTLTSAAGTVLAAIKAIEHGVAIHLSGGYHHAHKDFGSGFCLLNDLVLAAHFGLQRENIDKVLIIDSDVHQGDGTATLCQERDDIITLSFHCDKNFPARKPDSDLDLPLTRGTDDDSFLATFKQVVEMAVNLHQPDLIIYDAGVDIHQDDELGYLNISTQAIYQRDHFLFDTMKQRGIPVAAVVGGGYRTEQSALVPIHFQLIQAAFDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM4</accession>
    <name>B1KFM4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional uridylyltransferase/uridylyl-removing enzyme</fullName>
            <shortName evidence="8">UTase/UR</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Bifunctional [protein-PII] modification enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Bifunctional nitrogen sensor protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="8">[Protein-PII] uridylyltransferase</fullName>
                <shortName evidence="8">PII uridylyltransferase</shortName>
                <shortName evidence="8">UTase</shortName>
                <ecNumber evidence="8">2.7.7.59</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">[Protein-PII]-UMP uridylyl-removing enzyme</fullName>
                <shortName evidence="8">UR</shortName>
                <ecNumber evidence="8">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">glnD</name>
        <name evidence="11" type="ordered locus">Swoo_3942</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13673"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
            <dbReference type="EC" id="2.7.7.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:48600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14253"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:77828"/>
            <dbReference type="EC" id="3.1.7.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GlnD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.59" evidence="8"/>
    <dbReference type="EC" id="3.1.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326529.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3942"/>
    <dbReference type="EnsemblBacteria" id="ACA88199">
        <property type="protein sequence ID" value="ACA88199"/>
        <property type="gene ID" value="Swoo_3942"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3942"/>
    <dbReference type="eggNOG" id="COG2844">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012833_0_0_6"/>
    <dbReference type="OMA" id="PGGMRDI"/>
    <dbReference type="OrthoDB" id="162558at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008893">
        <property type="term" value="F:guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00277">
        <property type="entry name" value="PII_uridylyl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010043">
        <property type="entry name" value="UTase/UR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47320">
        <property type="entry name" value="PTHR47320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006288">
        <property type="entry name" value="PII_uridyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01693">
        <property type="entry name" value="UTase_glnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2 8 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="10">
        <location>
            <begin position="448"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="688"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="794"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uridylyltransferase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="868" mass="99395" checksum="021738698981F2FD" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV9</accession>
    <name>B1KFV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323622.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0982"/>
    <dbReference type="EnsemblBacteria" id="ACA85275">
        <property type="protein sequence ID" value="ACA85275"/>
        <property type="gene ID" value="Swoo_0982"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0982"/>
    <dbReference type="eggNOG" id="ENOG502ZI8Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157281_0_0_6"/>
    <dbReference type="OMA" id="QDNYRPY"/>
    <dbReference type="OrthoDB" id="1978287at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767030" evidence="1">
        <location>
            <begin position="24"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="13316" checksum="DC4F0FB961054B9F" modified="2008-04-29" version="1" precursor="true">MNICRRKIVSTLALLFVAGFAHAAAAGQVVVRKSSEPFDAFAVRDQVLLEHEWKEALRMQQQIQILQALPLACTPYSRPYIYYRCNGLFYRPYQYKNKELYIQVDDVMPASELVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW1</accession>
    <name>B1KFW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323624.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85277">
        <property type="protein sequence ID" value="ACA85277"/>
        <property type="gene ID" value="Swoo_0984"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0984"/>
    <dbReference type="eggNOG" id="ENOG5032T40">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_619479_0_0_6"/>
    <dbReference type="OMA" id="VAIMRTQ"/>
    <dbReference type="OrthoDB" id="1272040at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031979">
        <property type="entry name" value="DUF4785"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16024">
        <property type="entry name" value="DUF4785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764420" evidence="2">
        <location>
            <begin position="25"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="429" mass="46439" checksum="74C451D3287E7956" modified="2008-04-29" version="1" precursor="true">MKKLTHLATSLAMASLLVACQDDAQTEEPQAEVTKQQTKSFTLAAPQTGDFSSTEINEPTLPPINSSPEAVSFVTKVSSDFTLTPPVRARSVQSDEYWTKVTGDELNRGVKLAISQASSVIRISPRGDTSSGTLTHSKAIEPETIQLLKEGAKESQSRSYIKSLADSQALATAGLTDDSSALILSSDATAGQYRLKVSEKLEPDASYMVNVKEKHSPYKLKLTSKDSLSSAQTSMPFQLELSNNQTQLKPKASLKHANGHYQALEVEQVNGQWSAKLPELDAMPVSNSGLSEIQLEVQTDVAGEQVIRTVKKAFKQFVPSAKIQPEVSTSWEQGVPSSLTVSLEMKKAGRFSVAGFLTGVDTQGNDKPILRTESADWLTPDSTKLTLKLDTQLIAQSGLKPPYKLQGLTLKDQGQMARLSYQAHGVTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG28</accession>
    <name>B1KG28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325077.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2458"/>
    <dbReference type="EnsemblBacteria" id="ACA86735">
        <property type="protein sequence ID" value="ACA86735"/>
        <property type="gene ID" value="Swoo_2458"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2458"/>
    <dbReference type="eggNOG" id="COG3531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239444_0_0_6"/>
    <dbReference type="OMA" id="DSHCPWS"/>
    <dbReference type="OrthoDB" id="996965at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="216" mass="24000" checksum="F667ECD8690974D6" modified="2008-04-29" version="1">MTTELSTQEFVTPETSSLDLYFIYDSHCPWSYATTPLVNALSEAFPDMNLHLLHCAHFNGSDAAGQEQVDSVLKLSGVKFGREHIRYVNSPKNAVKTANLMAWMQSKQPKKLLPVLNALQKAHFVEGNPLDSKHDFNDIVEQFKLSPSNKVFKDELSSDAEFVLADIAEIQTMIETNAFPVLLMIADEQGIFIDHSQHLGAPLGVVEAVKKELSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG45</accession>
    <name>B1KG45_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfur relay protein TusC/DsrF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DsrF/TusC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325094.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2475"/>
    <dbReference type="EnsemblBacteria" id="ACA86752">
        <property type="protein sequence ID" value="ACA86752"/>
        <property type="gene ID" value="Swoo_2475"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2475"/>
    <dbReference type="eggNOG" id="COG2923">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155943_1_0_6"/>
    <dbReference type="OMA" id="LEMILIM"/>
    <dbReference type="OrthoDB" id="1768076at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017462">
        <property type="entry name" value="Sulphur_relay_TusC/DsrF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38780">
        <property type="entry name" value="PTHR38780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03010">
        <property type="entry name" value="sulf_tusC_dsrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="12726" checksum="4E062E808BA1A16B" modified="2008-04-29" version="1">MKKLTIIFRRAPHGSPHGREALDLALLSASFEQEVSLIFADEGVLNLVKTQQPELVGAKDFIATFGALPLYDIDTILACEASLQEYGLANAELTIAPSIVAPSTIREQLASADEVLVF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG58</accession>
    <name>RL20_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplT</name>
        <name type="ordered locus">Swoo_2488</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325107.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG58"/>
    <dbReference type="SMR" id="B1KG58"/>
    <dbReference type="STRING" id="392500.Swoo_2488"/>
    <dbReference type="EnsemblBacteria" id="ACA86765">
        <property type="protein sequence ID" value="ACA86765"/>
        <property type="gene ID" value="Swoo_2488"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2488"/>
    <dbReference type="eggNOG" id="COG0292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123265_0_1_6"/>
    <dbReference type="OMA" id="GRRKNVW"/>
    <dbReference type="OrthoDB" id="1932144at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000122372" description="50S ribosomal protein L20">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <sequence length="119" mass="13698" checksum="A824BA026E109B69" modified="2008-04-29" version="1">MPRVKRGVTARARHKKVLKLAKGYYGARSRTYRVAVQAVTKAGQYAYRDRRQKKRQFRQLWIARINAASRQNGLSYSRFINGLKKASIEIDRKILADIAVFDKVVFTTLVEKAKEALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGJ7</accession>
    <name>B1KGJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MltA-interacting MipA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MipA/OmpV family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323672.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1032"/>
    <dbReference type="EnsemblBacteria" id="ACA85325">
        <property type="protein sequence ID" value="ACA85325"/>
        <property type="gene ID" value="Swoo_1032"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1032"/>
    <dbReference type="eggNOG" id="COG3713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063465_0_0_6"/>
    <dbReference type="OMA" id="HYHADAG"/>
    <dbReference type="OrthoDB" id="1497770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010583">
        <property type="entry name" value="MipA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38776">
        <property type="entry name" value="PTHR38776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06629">
        <property type="entry name" value="MipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767340" evidence="5">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="33770" checksum="EF08E3E29F5048B2" modified="2008-04-29" version="1" precursor="true">MNRLKLLFLSAIFIPFLSWGDIDVPCENDLECIEVGQWDLGIAFGYGERSNPLKDYSDIPIYLVPTFAYYGDSWFFDNGNIGYTLVEEERYTLNLSTSFSTDSAYFQRWDPSNIFLAGSNKFEANSIAANGRTLLMSDEPEPDVGPLEKRRFTYLGGLDAFIYTRAGIINLSVAHDMLNVHQGTEARLKWLYNFPVQNWNFEFALRLDWKSEEVVDYYYGVRESESPYWNQAYQAKSALNVGIELTTHYVMTQHWDLIFLARYTQIADEIANSPLLDQDHTSTFYLGTSYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH06</accession>
    <name>B1KH06_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0276 protein Swoo_4062</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0276 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326647.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4062"/>
    <dbReference type="EnsemblBacteria" id="ACA88318">
        <property type="protein sequence ID" value="ACA88318"/>
        <property type="gene ID" value="Swoo_4062"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4062"/>
    <dbReference type="eggNOG" id="COG3220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064263_0_0_6"/>
    <dbReference type="OMA" id="THDHPVC"/>
    <dbReference type="OrthoDB" id="1602134at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00697">
        <property type="entry name" value="UPF0276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007801">
        <property type="entry name" value="UPF0276"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42194">
        <property type="entry name" value="PTHR42194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05114">
        <property type="entry name" value="DUF692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="34872" checksum="0B300B88759EDC35" modified="2008-04-29" version="1">MTETALTQDFLGFGLGLRTNHFDHVLTNRPDIDWFEVLSENYMVAGGKPRYYLEAIAEQYPIVMHGVSMSIGSTDPLDREYLTALKKLANDVQPQWISDHICWTSIHGVNSHDLLPLPYTEETIKHVAERVRQVQDFLGRRILLENVSSYLSYQDSTMDEWAFLNAVAEQADCLILLDINNIYVSARNHNFDPVTYLNKIDPKRVQQFHLAGHSDYGDYVVDTHDHDVPNSVWELYRIALERFGAISTMIERDGNIPEFPALEQELQIARDIAEKTLPELASQLASINEQAQKQSLKTGMFDDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH65</accession>
    <name>B1KH65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326706.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4121"/>
    <dbReference type="EnsemblBacteria" id="ACA88377">
        <property type="protein sequence ID" value="ACA88377"/>
        <property type="gene ID" value="Swoo_4121"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4121"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036480_2_0_6"/>
    <dbReference type="OMA" id="ITQMAFL"/>
    <dbReference type="OrthoDB" id="958173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="437" mass="49251" checksum="B45E354E7FA21D6A" modified="2008-04-29" version="1" precursor="true">MNIKSYIAKVWLARGWILSLSLALSLTSIHSLQAEESEFDLTFSGFGTLGVVHNSSDALKFHSELTVKPASNTYSFNADSLIGLQLNARLPKRFDAVAQVVIKDRISSEAIDSLELLFLRYRPSRNWALRVGRTSSDLYMLSEYRNVGYAYLWARPITEFYELSTSIAKIDGVDVSYVANLGDGVWENKLAYGRSHSVLSANANQFEIDLKNVVVFSSIFTQAPWLFRLAITDAEVDEVDFVTQNLVEGLRALPPQLWPDAASISNVLDGPKKGIQYYALGLQYDSDRWVVQSEFSLTESDWGIVPPYYTGYLSVGYRFDNLTFYSVASYLNNVDDPISFKSPQVPTQLLPPEVVGQINGLYQGSQFAVNAVRGEQRTYSLGVRWDLYPNTSLKFQWDHTKVDMAGNVLWTKPNSMPQLQDENINLFSLNFSFIFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH84</accession>
    <name>B1KH84_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1099</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323738.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1099"/>
    <dbReference type="EnsemblBacteria" id="ACA85392">
        <property type="protein sequence ID" value="ACA85392"/>
        <property type="gene ID" value="Swoo_1099"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1099"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_4_1_6"/>
    <dbReference type="OMA" id="IHEWPYL"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="7">
        <location>
            <begin position="35"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="6">
        <location>
            <begin position="178"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="405" mass="44416" checksum="3F07BB902AC54D04" modified="2008-04-29" version="1">MTLGVGGSTAEQELAKLTDMTEGTGPISYDEYSRRIEKAQALMTAEGIEAIYVNAGTNLYYFTGTRWYASERMVGAIIPAKGKLEYIAPAFELDTLEGFMVVKGKVNTWHEDESPYSLFGDALIQMGVNSGKVGIDESAAFFIFDGVRQAHNQFEYVNAKPVTAGCRMIKSEVELSLLQRAKDMTLEVHKAVARILHEGISVGEVEAFIHEAHKRVGAPAGSYFCIVLFGEDSAYPHGVKSPKVLELNDTVLIDTGCQLQGYNSDITRTFVFGTPSARQRELWQYEQDAQLAAFDAAKIGSTCASVDRAARDVLEAAGFGPGYNLPGLPHRTGHGIGLDIHEWPYLVLNDQTPLAAGMCFSNEPMLCVPGEFGVRHEDHFYMTETGPVWFTQPAHSIDDPFGYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHD6</accession>
    <name>B1KHD6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323790.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1151"/>
    <dbReference type="EnsemblBacteria" id="ACA85444">
        <property type="protein sequence ID" value="ACA85444"/>
        <property type="gene ID" value="Swoo_1151"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1151"/>
    <dbReference type="HOGENOM" id="CLU_481359_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="566" mass="64345" checksum="3E470BB858424876" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE4</accession>
    <name>B1KHE4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7,8-dihydroneopterin aldolase</fullName>
            <ecNumber evidence="1">4.1.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHNA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323798.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1159"/>
    <dbReference type="EnsemblBacteria" id="ACA85452">
        <property type="protein sequence ID" value="ACA85452"/>
        <property type="gene ID" value="Swoo_1159"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1159"/>
    <dbReference type="eggNOG" id="COG1539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112632_0_2_6"/>
    <dbReference type="OMA" id="GIYEWEK"/>
    <dbReference type="OrthoDB" id="1858654at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00534">
        <property type="entry name" value="DHNA_DHNTPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="PTHR42844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00525">
        <property type="entry name" value="folB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="2">
        <location>
            <begin position="4"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="117" mass="13192" checksum="0343370B3BAA8F04" modified="2008-04-29" version="1">MDRVLIRQLKIETIIGIYEWEKQIHQTLLVDLDMAWDNKMAAATDDYQHALCYETVSNRLTALITQKPIELIETVAEMIANCLLTEFNVPWVKVTIMKPGAVPTAAAVGVEIERGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE7</accession>
    <name>B1KHE7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">rRNA (Guanine-N(1)-)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1162</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323801.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1162"/>
    <dbReference type="EnsemblBacteria" id="ACA85455">
        <property type="protein sequence ID" value="ACA85455"/>
        <property type="gene ID" value="Swoo_1162"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1162"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050931_0_0_6"/>
    <dbReference type="OMA" id="MTPYAWR"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016718">
        <property type="entry name" value="rRNA_m1G-MeTrfase_A_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018249">
        <property type="entry name" value="MyrA_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="3">
        <location>
            <begin position="91"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="97"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR018249-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR018249-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="32770" checksum="2C503B788CB5477D" modified="2008-04-29" version="1">MKSLYLCPVCDQPLLIHEASGGLHCAKKHHLDKHENGYWIFSQAKKPQIDSRQVMRAKRFLLESGIFQPVVDNVEAMIRKADLATGEISYLDYDCGEGYYLRAIKALLAQSPEGQGIASQMSAYGITEAENALFSAAKIQAEANSLLEEGDEQNDSTFIVSTLKRLPFVDESFELITLIDKQLKGKELIRVLKPGGYLIQVSPAPRHLWQIKSHVYPDLTEKAVNLPKSAELELLHTEQVSFTLCVDGAQALALLEMTPYAWRANEKVRKQLASSSFDKLEIDFMITLSKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL2</accession>
    <name>B1KHL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325237.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2620"/>
    <dbReference type="EnsemblBacteria" id="ACA86897">
        <property type="protein sequence ID" value="ACA86897"/>
        <property type="gene ID" value="Swoo_2620"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2620"/>
    <dbReference type="eggNOG" id="COG1322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024057_0_0_6"/>
    <dbReference type="OMA" id="GDSKMQG"/>
    <dbReference type="OrthoDB" id="1309809at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="98"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="498" mass="57170" checksum="AF5A61BB61FDA457" modified="2008-04-29" version="1">MPIDITLTAPQIAALIAIAFLSLLIGALLNQKLTRRRWELSKEHLNNIHQQEIEQYQQDLQHKESILCEKEQQQEQLQFKLEQQLSALGKAQADAERCSGLELQLKENQRKLMEAQLALSKSNAMQQTLRVKFEAEQQALEDKLALLESAEVRLNTQFENLANKIFEERSEKFQHQNTNQLDSVLAPFKQQLEGFRKQVNESYTNEQSQRSAFNHQLESLKALNLQMSRDAVNLTNALKGDNKQQGNWGEVILERVLQESGLREGHEYDTQTDLKNDDGKRFKPDVIVHLPENKDVVIDAKMSLVAYERYFNSDEEDVRKQALKEHVISVRGHIKGLSNKDYQKLHGLTSLDYVLMFIPLEPAFLLALEHDPSLVNYALEQNIMIVSPTNLLVALRTINNIWRYEYQNQNAQQIAKQAGKIYDKLCGYIEDMEKLGRAIEGAEKSYSNAMNKLSSGKGNLIKQAHQMQQLGVDTSKKIDQRMLDQALSDYQLDDKPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHN0</accession>
    <name>B1KHN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CBS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325255.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2638"/>
    <dbReference type="EnsemblBacteria" id="ACA86915">
        <property type="protein sequence ID" value="ACA86915"/>
        <property type="gene ID" value="Swoo_2638"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2638"/>
    <dbReference type="eggNOG" id="ENOG502ZA6M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111127_0_0_6"/>
    <dbReference type="OMA" id="FCSELGA"/>
    <dbReference type="OrthoDB" id="1812980at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009339">
        <property type="entry name" value="DUF998"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06197">
        <property type="entry name" value="DUF998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="22038" checksum="DBE8425FD376EBD8" modified="2008-04-29" version="1">MFETFSIYSGLIATTWITIGVYIASQFYAGYDHSRQFCSELGATGSPTEKLSPLINNYPLGALFCLFGWYLAQMTNVSILVNITGWLVIIHGVGTWVAGYFPMDADPFTKNPTFNCKVHSWAGFIMLLSLVIAPILIAISPTSSAVPLAFRLFSMVSVIGAVYYLLAMAKAVKAQANAGIYQRISYGFQLIWLSVFSLVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS4</accession>
    <name>B1KHS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326731.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88402">
        <property type="protein sequence ID" value="ACA88402"/>
        <property type="gene ID" value="Swoo_4146"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4146"/>
    <dbReference type="eggNOG" id="ENOG5031JCV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_210085_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021494">
        <property type="entry name" value="DUF3149"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11346">
        <property type="entry name" value="DUF3149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="42" mass="4918" checksum="A357935DD7AEF50F" modified="2008-04-29" version="1">MAFWLDLMFGNPIGLLSMIVIFCTIGIMSYLMWMFIQKSKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI39</accession>
    <name>B1KI39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323863.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1224"/>
    <dbReference type="EnsemblBacteria" id="ACA85517">
        <property type="protein sequence ID" value="ACA85517"/>
        <property type="gene ID" value="Swoo_1224"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1224"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_6"/>
    <dbReference type="OMA" id="HCMTGHA"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="33694" checksum="F3257C0A9C151667" modified="2008-04-29" version="1">MKHLPSLKNLFYLVNLYQEQNFNRAAKMCHVSQSTLSSGIQNLEEQLGHQLIERDHKSFIFTAIGEEVVLRSRKLLTDVDDLVELVKHQGEPMTGDIRLGCIPTIAPFLLSRVVKQCQQTYPNLTMFLKEDTTERLLDALGKGELDLLLLALPVDTSGYHSMKVGIDPFKLVVHNDLAGEIHEPLDYQSLPDESIFLLQAEHCITGHAVSACQLGDSAKVNPFAATSLHTLVQMVNGKLGTTFLPQMAIDAGILNDTDLEVMQPPGEAPYRDIGLVWRQTSSRILTFRTLGLAIQELLAKEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI45</accession>
    <name>B1KI45_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Thymidylate synthase</fullName>
            <shortName evidence="4">TS</shortName>
            <shortName evidence="4">TSase</shortName>
            <ecNumber evidence="1 4">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">thyA</name>
        <name evidence="6" type="ordered locus">Swoo_1230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323869.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1230"/>
    <dbReference type="EnsemblBacteria" id="ACA85523">
        <property type="protein sequence ID" value="ACA85523"/>
        <property type="gene ID" value="Swoo_1230"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1230"/>
    <dbReference type="eggNOG" id="COG0207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021669_0_1_6"/>
    <dbReference type="OMA" id="KQYLDLC"/>
    <dbReference type="OrthoDB" id="1212177at2"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="5">
        <location>
            <begin position="2"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="180"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="283" mass="32266" checksum="AF98525337709C75" modified="2008-04-29" version="1">MKQYLDLCNRIIDEGTWIENERTGKRCLTVINADLVYNVADNEFPLITTRKSFWKSAIAEMLGYIRGYDNAADFRKLGAKTWDANANENQAWLNNSHRKGEDDMGRVYGVQGRAWSKPDGGSVDQLRKIVDNLKNGVDDRGEILSFYNPGEFHMGCLRPCMHTHNFSMLGDTLYLNSFQRSCDVPLGLNFNQVQVFALLAIVAQITGKKAGMAYHKIVNAHIYEDQLELMRDVQLKREPFAPASLTINPDIKSLEDLETWVTMDDFEVSGYQHHDAIKYPFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC7</accession>
    <name>B1KIC7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="1">1.1.1.42</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Oxalosuccinate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the monomeric-type IDH family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325315.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2702"/>
    <dbReference type="EnsemblBacteria" id="ACA86978">
        <property type="protein sequence ID" value="ACA86978"/>
        <property type="gene ID" value="Swoo_2702"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2702"/>
    <dbReference type="eggNOG" id="COG2838">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025308_1_0_6"/>
    <dbReference type="OMA" id="FRMCQTK"/>
    <dbReference type="OrthoDB" id="222705at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004436">
        <property type="entry name" value="Isocitrate_DH_NADP_mono"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36999">
        <property type="entry name" value="PTHR36999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03971">
        <property type="entry name" value="IDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009407">
        <property type="entry name" value="IDH_monmr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00178">
        <property type="entry name" value="monomer_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0521">NADP</keyword>
    <keyword evidence="1 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="133"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="83"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="548"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="585"/>
            <end position="586"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="601"/>
            <end position="603"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="650"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="2">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR009407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR009407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR009407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR009407-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009407-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="740" mass="80227" checksum="5B661FA2A5F23C30" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE6</accession>
    <name>B1KIE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325334.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2721"/>
    <dbReference type="EnsemblBacteria" id="ACA86997">
        <property type="protein sequence ID" value="ACA86997"/>
        <property type="gene ID" value="Swoo_2721"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2721"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_6"/>
    <dbReference type="OMA" id="VYAMREK"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="24371" checksum="6BCB7311FD3EC73B" modified="2008-04-29" version="1">MKLENLNIIIADDHPLFRNALRQALSGPFADTHWFEADSAEALQTLLEKSDVEYDLVLLDLQMPGSHGYSTLIHLRTHYPELPVVVISAHEDNITISRAVHYGSAGFIPKSSSMDSLAEALTSVLYGDIWLPQDVELQDIEEDATALIASKLSDLTPQQYKVLQMFAEGLLNKQIAYDLGVSEATIKAHATAIFRKLGVRNRTQAVISLQQLEMEKVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII3</accession>
    <name>B1KII3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein ZapE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Z ring-associated protein ZapE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">zapE</name>
        <name evidence="4" type="ordered locus">Swoo_4223</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Reduces the stability of FtsZ polymers in the presence of ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AFG1 ATPase family. ZapE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326806.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4223"/>
    <dbReference type="EnsemblBacteria" id="ACA88479">
        <property type="protein sequence ID" value="ACA88479"/>
        <property type="gene ID" value="Swoo_4223"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4223"/>
    <dbReference type="eggNOG" id="COG1485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008681_0_4_6"/>
    <dbReference type="OMA" id="QKREYWE"/>
    <dbReference type="OrthoDB" id="607330at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01919">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030870">
        <property type="entry name" value="ZapE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="PTHR12169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="70"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="368" mass="42434" checksum="EC39CE06A503116C" modified="2008-04-29" version="1">MPQPTPWQHYQQDLTRDDFSHDSAQEQAVKSLQRVYDEIQVANSKPTGFRQLFSFLGAKEQTVQGLYLWGGVGRGKTYLMDTFYDSLPGDKKLRAHFHRFMHQVHVDLDNLKGQRDPLLIIAKQMADKYQVICFDEFFVSDITDAMLLGTLFQALFKEGVALVATSNIIPDELYRNGLQRARFLPAIALINKHCQILNVDSGIDYRLRTLEQAEIYHYPLDTQADKNLLSYFEKLAPESEISRSDIDIDGRNIGIRQQAQGVLLIDFRDLCDGPRSQRDYMELACLYHTVLLSGVEQMGDKSTGDDIARRFLAMVDEFYERNVKLILSAEVSLEEIYTQGLLTFEFRRCRSRLTEMQSHDYLALEHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII4</accession>
    <name>B1KII4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4224</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326807.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4224"/>
    <dbReference type="EnsemblBacteria" id="ACA88480">
        <property type="protein sequence ID" value="ACA88480"/>
        <property type="gene ID" value="Swoo_4224"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4224"/>
    <dbReference type="eggNOG" id="COG3105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163402_0_0_6"/>
    <dbReference type="OMA" id="EVTDHFE"/>
    <dbReference type="OrthoDB" id="1875166at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009386">
        <property type="entry name" value="DUF1043"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06295">
        <property type="entry name" value="DUF1043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="14149" checksum="7EF96873A7CF0309" modified="2008-04-29" version="1">MEWPLVVATFVLGIVLGYVIRTIFAKNHESNDKDEALEQTRLELSQHKQEVTDHFEDHYQQLAELTEQLNKVNKKWNEAANTLAPKNSVKPLATLTSDKAEHSKQQDQANELDSQDVIIVNPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIW1</accession>
    <name>B1KIW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323955.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85609">
        <property type="protein sequence ID" value="ACA85609"/>
        <property type="gene ID" value="Swoo_1317"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1317"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071003_1_2_6"/>
    <dbReference type="OMA" id="GNYRAGF"/>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767381" evidence="1">
        <location>
            <begin position="23"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="24"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="20615" checksum="6C2E2F4B4FFC75AE" modified="2008-04-29" version="1" precursor="true">MKKHLLVTALTASLFLGNAAQAADYIVDTDGAHASIQFRVSHLGYSYVAGRFNDFKGDFSFDANKVADAKVNMVINTTSIDSNHAERDKHLRSADFLNTAKFPQATFTSTSVEDKGNGDFILNGNFTLNGVTKPLAISATTVGEGQDPWGGYRVGFTGTTEFALKDYDIKMDLGPASSHVKLDLVVEGIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIZ4</accession>
    <name>B1KIZ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1350"/>
    <dbReference type="EnsemblBacteria" id="ACA85642">
        <property type="protein sequence ID" value="ACA85642"/>
        <property type="gene ID" value="Swoo_1350"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1350"/>
    <dbReference type="eggNOG" id="COG1785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008539_4_1_6"/>
    <dbReference type="OMA" id="DNFYTIA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764545" evidence="2">
        <location>
            <begin position="20"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="496" mass="52929" checksum="5BEEEECE1AD29C55" modified="2008-04-29" version="1" precursor="true">MKIVAALVSCSLVTITANAAVLPTNQTDSEWFKSSALKVTEKTQQVNKEKAKNVILFVGDGMGISTLTAARIFQGQQIEGNMGGEENFLSFEQFPHTALVKTYNTNQQTPDSAGTMTAMVTGVKSKAGVLSVSDTSLRANCLSSKGNELTTLVDLANAKGLSTGVVSTARITHATPAAAYSSTPERGWEADSNLPAEAITNECKDIAYQLVMRDEDNALTVALGGGRRNFIPDTITDGEDKKGRRSDGVDLTKSWTDNLSNAAYVWDKTGFDAIDTASTEHLLGLFNSSHMEYEADRMDDTAGEPSLTEMTTKSIDILKKNDQGYLLIVESGRIDHGHHAGNAHRALMDAVELSNAVQAAIDSTDPEETLIMVTADHSHVFTIAGYPKRGNPILGLVHNVDGNVATAKDGKPYTTLGYTNGPGAVVGLRDDLSSVDTQEKSFKQQALIPMGSETHAGEDISLHATGPGSHLVQGVIEQNVIFHIINQAQSLGGTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ06</accession>
    <name>B1KJ06_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324000.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1362"/>
    <dbReference type="EnsemblBacteria" id="ACA85654">
        <property type="protein sequence ID" value="ACA85654"/>
        <property type="gene ID" value="Swoo_1362"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1362"/>
    <dbReference type="eggNOG" id="COG1432">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092340_3_1_6"/>
    <dbReference type="OMA" id="CSHLRHE"/>
    <dbReference type="OrthoDB" id="1891199at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="157" mass="17621" checksum="C3BC5813F4EC57AA" modified="2008-04-29" version="1">MKKIALFVDVQNIYYTCRQAHGRQFNYRKLWQHISHEGEIVSATAYAIHKGDDGQLKFQDALKHIGFDVKLKPFIQRADGSAKGDWDVGITIDIMEAASEVDSIILLSGDGDFDLLMLKIYQKYGIETQVYGVPGLTAKSLIDSAAKYHEIDDALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ80</accession>
    <name>B1KJ80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2825</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325436.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2825"/>
    <dbReference type="EnsemblBacteria" id="ACA87100">
        <property type="protein sequence ID" value="ACA87100"/>
        <property type="gene ID" value="Swoo_2825"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2825"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_4_6"/>
    <dbReference type="OMA" id="FHRAINI"/>
    <dbReference type="OrthoDB" id="1098559at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="223" mass="24928" checksum="7EEC2F8BDC54E847" modified="2008-04-29" version="1">MSRSTPIIHKTRTQVVVEVLREKILSGDIAAGEPLRQSALAEELNVSRIPVREALLQLEAEGLVKFEAHKGATATELSVEQVTELFELRAMIETDLLAKAIPNLQDEDFLQAEKVLGELESAFKQEDAVATWSELNTRFHTCLYSPANRPHTLEVVHGLNTNCDRYIRLQLLLAGGIPRAEQDHRDLLSFCKNQQTDKAVELLRAHILHAADAIRDLVAQQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA0</accession>
    <name>B1KJA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4319"/>
    <dbReference type="EnsemblBacteria" id="ACA88572">
        <property type="protein sequence ID" value="ACA88572"/>
        <property type="gene ID" value="Swoo_4319"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4319"/>
    <dbReference type="eggNOG" id="ENOG50335WT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2991390_0_0_6"/>
    <dbReference type="OMA" id="WHLEQAR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="55" mass="6134" checksum="D5340AE785CEE9FF" modified="2008-04-29" version="1">MNVDQHLKVAQWHIEQARLHATSEHACGCPANDHDQKAIDAVEANLILEEKTCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI7</accession>
    <name>B1KJI7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324006.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1368"/>
    <dbReference type="EnsemblBacteria" id="ACA85660">
        <property type="protein sequence ID" value="ACA85660"/>
        <property type="gene ID" value="Swoo_1368"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1368"/>
    <dbReference type="HOGENOM" id="CLU_176325_0_0_6"/>
    <dbReference type="OMA" id="RFSWFES"/>
    <dbReference type="OrthoDB" id="1774886at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767128" evidence="1">
        <location>
            <begin position="22"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="11553" checksum="5B3A2EF55C1F3A4C" modified="2008-04-29" version="1" precursor="true">MKKLLWVISLCCLWLSFSTTAEERADYKCYVDTNQGHKVVRFSWYPSKTKLYMARFVGKRMTSDKGSQPLYIKSMLECVNVTQSFNKPQARAVEQRTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM1</accession>
    <name>B1KJM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324040.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1402"/>
    <dbReference type="EnsemblBacteria" id="ACA85694">
        <property type="protein sequence ID" value="ACA85694"/>
        <property type="gene ID" value="Swoo_1402"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1402"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_4_7_6"/>
    <dbReference type="OMA" id="HGGYWRM"/>
    <dbReference type="OrthoDB" id="1470522at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="96"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="36263" checksum="ABE12E4D2951A786" modified="2008-04-29" version="1">MSATDRDKLEIAPFDKAPLEKEALEIEYSPSSCVDDIMIYIQQYIDQSQTVIEQAVSENSVLRDLKYADSDNTGKDEVLDLFLPTHHSARGKKLHVYIHGGYWQELTKEESAFAARAFQQAGHYFAVINYSLAPKASLTEIVEQNRRALAWLVSHADELGFDADEVYLSGSSAGAHLCLMMLQTNWQGYLTSNHLSNNDLANSPVTFAPEKPFIKGICAVSGIYDIAPLLHTTINDPLQLTEQEVEANSPLRHATQHHCPVIIAFGDNETSEFKRQSLAMLAQLEDQGFDITFSEIAGRNHFDVILDLGIEGRWLFEEVLKQMG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJV0</accession>
    <name>NUOCD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit C/D</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit C/D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit C/D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoC</name>
        <name evidence="1" type="synonym">nuoCD</name>
        <name evidence="1" type="synonym">nuoD</name>
        <name type="ordered locus">Swoo_2862</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325473.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJV0"/>
    <dbReference type="SMR" id="B1KJV0"/>
    <dbReference type="STRING" id="392500.Swoo_2862"/>
    <dbReference type="EnsemblBacteria" id="ACA87137">
        <property type="protein sequence ID" value="ACA87137"/>
        <property type="gene ID" value="Swoo_2862"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2862"/>
    <dbReference type="eggNOG" id="COG0649">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_3_2_6"/>
    <dbReference type="OMA" id="GGRMHYM"/>
    <dbReference type="OrthoDB" id="473681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030964">
        <property type="term" value="C:NADH dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01359">
        <property type="entry name" value="NDH1_NuoCD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023062">
        <property type="entry name" value="NADH_DH_suCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="PTHR11993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000358694" description="NADH-quinone oxidoreductase subunit C/D">
        <location>
            <begin position="1"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADH dehydrogenase I subunit C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADH dehydrogenase I subunit D" evidence="1">
        <location>
            <begin position="214"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01359"/>
        </source>
    </evidence>
    <sequence length="598" mass="68439" checksum="2D25B4E8F8209F8F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJX5</accession>
    <name>B1KJX5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Phosphate acetyltransferase</fullName>
            <ecNumber evidence="6 12">2.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Phosphotransacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_2887</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in acetate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>acetyl-CoA + phosphate = acetyl phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19521"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">In the N-terminal section; belongs to the CobB/CobQ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.8" evidence="6 12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325498.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2887"/>
    <dbReference type="EnsemblBacteria" id="ACA87162">
        <property type="protein sequence ID" value="ACA87162"/>
        <property type="gene ID" value="Swoo_2887"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2887"/>
    <dbReference type="eggNOG" id="COG0280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0857">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019723_2_1_6"/>
    <dbReference type="OMA" id="FFMCLAD"/>
    <dbReference type="OrthoDB" id="1301815at2"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008959">
        <property type="term" value="F:phosphate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016475">
        <property type="entry name" value="P-Actrans_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004614">
        <property type="entry name" value="P_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006107">
        <property type="entry name" value="PhpActrans_proteobac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00651">
        <property type="entry name" value="pta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DRTGG" evidence="15">
        <location>
            <begin position="233"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="PTA_PTB" evidence="14">
        <location>
            <begin position="391"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA87162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="713" mass="77345" checksum="B46C695F7415145C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJY6</accession>
    <name>B1KJY6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325509.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2900"/>
    <dbReference type="EnsemblBacteria" id="ACA87173">
        <property type="protein sequence ID" value="ACA87173"/>
        <property type="gene ID" value="Swoo_2900"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2900"/>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012428_0_0_6"/>
    <dbReference type="OMA" id="CHRPEGN"/>
    <dbReference type="OrthoDB" id="41828at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022442">
        <property type="entry name" value="B-helix_rpt-cont_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022269">
        <property type="entry name" value="CHP03806_HNE0200"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022441">
        <property type="entry name" value="Para_beta_helix_rpt-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03805">
        <property type="entry name" value="beta_helix_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03806">
        <property type="entry name" value="chp_HNE_0200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03804">
        <property type="entry name" value="para_beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764977" description="Cytochrome c domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="661"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="880" mass="95028" checksum="B204DBFC39552408" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK15</accession>
    <name>B1KK15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tat (Twin-arginine translocation) pathway signal sequence domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325538.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2929"/>
    <dbReference type="EnsemblBacteria" id="ACA87202">
        <property type="protein sequence ID" value="ACA87202"/>
        <property type="gene ID" value="Swoo_2929"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2929"/>
    <dbReference type="eggNOG" id="ENOG502ZBQ1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102092_0_0_6"/>
    <dbReference type="OMA" id="WPLFGYE"/>
    <dbReference type="OrthoDB" id="1717246at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="19661" checksum="A7F8E73FCA7064C1" modified="2008-04-29" version="1" precursor="true">MSNNDHSTSRRKFLKNTGIGVAGTIVASTLSVTGSVAEEANNISLPDSPHVSKTLLKMAKDIYPHEMIQNKYYQKIVDDLAKQQKRLIDEGVAMLDEQSIAKLGSPFLQVNYEPDRVRLLRSIEETTFFIKVRTALMFGLYDNPELFPLFGYQGSSVEKGGYLNRGLNDLDWLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK39</accession>
    <name>B1KK39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MSHA biogenesis protein MshK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4418"/>
    <dbReference type="EnsemblBacteria" id="ACA88670">
        <property type="protein sequence ID" value="ACA88670"/>
        <property type="gene ID" value="Swoo_4418"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4418"/>
    <dbReference type="eggNOG" id="ENOG5033AIK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172550_0_0_6"/>
    <dbReference type="OMA" id="NQIFTLG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766737" evidence="2">
        <location>
            <begin position="24"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="116" mass="11971" checksum="38ECD4EB5AE5ADF6" modified="2008-04-29" version="1" precursor="true">MFQVKVNLSLAMLLLALTASTQAETLRDPTRPGSGGGSSTVSAQDMERGLTLNSVVSAGASSHAVINNQIFVVGDRVQGVKITGIGANSVSLADGRKLSMYQTITETKGSNSNDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK47</accession>
    <name>B1KK47_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="12" type="ordered locus">Swoo_4426</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327004.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4426"/>
    <dbReference type="EnsemblBacteria" id="ACA88678">
        <property type="protein sequence ID" value="ACA88678"/>
        <property type="gene ID" value="Swoo_4426"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4426"/>
    <dbReference type="eggNOG" id="COG1198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013353_3_1_6"/>
    <dbReference type="OMA" id="RCHYCGY"/>
    <dbReference type="OrthoDB" id="1132322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="213"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="473"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="731" mass="81102" checksum="C9279B5FF97B8B6B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK70</accession>
    <name>B1KK70_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate-binding and sugar hydrolysis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4449"/>
    <dbReference type="EnsemblBacteria" id="ACA88701">
        <property type="protein sequence ID" value="ACA88701"/>
        <property type="gene ID" value="Swoo_4449"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4449"/>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041882_0_1_6"/>
    <dbReference type="OMA" id="LYPEANF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006633">
        <property type="entry name" value="Carb-bd_sugar_hydrolysis-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026464">
        <property type="entry name" value="NosD_copper_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007742">
        <property type="entry name" value="NosD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022441">
        <property type="entry name" value="Para_beta_helix_rpt-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05048">
        <property type="entry name" value="NosD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00722">
        <property type="entry name" value="CASH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04247">
        <property type="entry name" value="NosD_copper_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03804">
        <property type="entry name" value="para_beta_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764983" evidence="1">
        <location>
            <begin position="19"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="CASH" evidence="2">
        <location>
            <begin position="44"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="CASH" evidence="2">
        <location>
            <begin position="192"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="447" mass="49408" checksum="BA8560C00EA3831B" modified="2008-04-29" version="1" precursor="true">MRYLGGCCLLLLSCFIQAEILYIDNPQTLNAQLQGAQPYDQLILAPGIYRGALVIDKPLSISNDMEGEVIIDAGGEGSAITITAPDVVVTGLSIRNWGNDHYEKDSGIRLLEGADRADISHNRFQGDGFGISADSLSHITIAGNTITGNGELYFLDRGDGIYLLNVISPSVSGNRISKVRDGIYLETGSFSRVFDNQFSDLQYGIHYMYTHSDEAFGNVSRHVEGGYALMSSKSINLHHNRVSHALDFGVLLNMTSLCLIESNEAELVSNPSEKVELGREGKGVFIYGARDNLVWNNQFSQNDIGIYMAMGGEGNRVFENRFIDNQSQVKYVGDALLEWSYGGRGNYWSSYQSWPRAGLQVGQDVYRPNDNLDRLFWLYPEANFLMGSPIVMLLKWAQREFDIVEDTGIIDSFPLSTPSASSGFIDESDMTIVESDSLSFGGIFYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKA1</accession>
    <name>B1KKA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327058.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4481"/>
    <dbReference type="EnsemblBacteria" id="ACA88732">
        <property type="protein sequence ID" value="ACA88732"/>
        <property type="gene ID" value="Swoo_4481"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4481"/>
    <dbReference type="eggNOG" id="COG3655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_31_8_6"/>
    <dbReference type="OMA" id="CRYLDCQ"/>
    <dbReference type="OrthoDB" id="2040098at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="69" mass="7670" checksum="588EFE93875A9311" modified="2008-04-29" version="1">MEIIVNLDVMMAVRKVSSKELAKAIGITEANLSLLKRGKVKGVRFETLASICGYLKCQPGDILEYREVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKK3</accession>
    <name>B1KKK3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2947</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325556.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2947"/>
    <dbReference type="EnsemblBacteria" id="ACA87220">
        <property type="protein sequence ID" value="ACA87220"/>
        <property type="gene ID" value="Swoo_2947"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2947"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="MYMAIKR"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="152"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="209"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="482" mass="51639" checksum="6353995AA38E04B2" modified="2008-04-29" version="1" precursor="true">MKQIQFRKIDALMIKLSLNGKFWLLCILVSLITTSIALVNLNKVQGQVEHSSQERAQAVVDTFANVVKSQGLSGDDLASFASSQGLQLNHTSVDNRQGNRVTVSAPIGRQYLQLTTDVKSWEAQALSDAKMMLWVALIGLLPLFQLSYWTSTSLGGGLWDMYVAIKRLADGDLTQRLNFFGKDDFSMIATEIDRSADNMSEMVTAIGHNAATLAQAADEFDQQAKQSEDLIGCQHQFLDSVAVAMDQMTAAIEEVSHNAANTSEQTQANTQQAQSSKQRIAEAVTRISTLVSEIDTASSSVSQLSNSASEIGAVVTTINGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIQSMIEGLQKGSSTLSKVTESIVEQADQGRNAIVSVGEDVDSMAGSTAGVFDMSSQIAASAEEQSVSARDIATQLNDIRDQSQIIKDTAQRSVTLAANLSNSSIELDKILTQYTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV3</accession>
    <name>B1KKV3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327085.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4508"/>
    <dbReference type="EnsemblBacteria" id="ACA88759">
        <property type="protein sequence ID" value="ACA88759"/>
        <property type="gene ID" value="Swoo_4508"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4508"/>
    <dbReference type="eggNOG" id="COG3248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072571_0_0_6"/>
    <dbReference type="OMA" id="EHADAWK"/>
    <dbReference type="OrthoDB" id="914393at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036777">
        <property type="entry name" value="Channel_Tsx-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111364">
        <property type="entry name" value="SSF111364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765010" evidence="1">
        <location>
            <begin position="19"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="250" mass="28410" checksum="D4F22EBD45110D65" modified="2008-04-29" version="1" precursor="true">MNKKWLALALFTTPPAMADDLIQWWDMSITAIHGDNYDLAPSEKQTTFTFETAGAWRYGDWFAFQDLVYFNGDNAGKDSTTYGEISARFSAGKITGNNIELGPITDLSLALTLEEGEGPVKSFLYGLGMDINIPYFSYFNLNTYRREALSSDNISDGWQVTPAFRMDFPVGSSNIVFDGFFDWVFSTDDANYEKNFHFNPQLKYDLGAVILGEHKKNKLFIGIEYDYWKNKYGVKGIAQSTYSVLAKYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY9</accession>
    <name>B1KKY9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327121.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4545"/>
    <dbReference type="EnsemblBacteria" id="ACA88795">
        <property type="protein sequence ID" value="ACA88795"/>
        <property type="gene ID" value="Swoo_4545"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4545"/>
    <dbReference type="eggNOG" id="ENOG5033MZH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138561_0_0_6"/>
    <dbReference type="OMA" id="AMTDYFE"/>
    <dbReference type="OrthoDB" id="1642338at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767168" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="29"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="17844" checksum="1D4312463CDBA607" modified="2008-04-29" version="1" precursor="true">MKPFLLVATLSVLPFTLSAATTPTSSEVVQSFIQAYNQHDVGLMVSHTTDDVTWMHITGKKVEVETSSKAEFGAAMTDYFESLKGANATILDMMESGNYVSTVERVTWDNDGEKLSQCSIGTFRVVDGKLAEFWYFPAHSCDELSTKPEVGPEVGVLQQTQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE2</accession>
    <name>B1KLE2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sialic acid biosynthesis protein NeuD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324213.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1581"/>
    <dbReference type="EnsemblBacteria" id="ACA85867">
        <property type="protein sequence ID" value="ACA85867"/>
        <property type="gene ID" value="Swoo_1581"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1581"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081811_2_3_6"/>
    <dbReference type="OMA" id="MPVNAIH"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd03360">
        <property type="entry name" value="LbH_AT_putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041561">
        <property type="entry name" value="PglD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020019">
        <property type="entry name" value="Sia_OAcTrfase_NeuD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17836">
        <property type="entry name" value="PglD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03570">
        <property type="entry name" value="NeuD_NnaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PglD_N" evidence="1">
        <location>
            <begin position="5"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="212" mass="22595" checksum="8AB316D5B357F5A7" modified="2008-04-29" version="1" precursor="true">MTKPVILLGSGGHASVLADILLQNNHTILAVISHSKSARSVFNEIQHFDSDKDVLQFSPDKVKLVNGLGSLPGQSLRHEIFDYFTQSNYQFETVISQNAMLSPYSTIGAGSQIFMGAIIQTGAVIGESTIINSGAIIEHDCHIGMHCHIAPGATICGDVRIGEHTHVATGANIIQGVSIGKHCIVAAGATVTKDMPDNSIAYGYRSQIEKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH8</accession>
    <name>B1KLH8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Flagellar hook-basal body complex protein FliE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fliE</name>
        <name evidence="6" type="ordered locus">Swoo_1617</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the FliE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324249.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1617"/>
    <dbReference type="EnsemblBacteria" id="ACA85903">
        <property type="protein sequence ID" value="ACA85903"/>
        <property type="gene ID" value="Swoo_1617"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1617"/>
    <dbReference type="eggNOG" id="COG1677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147249_0_0_6"/>
    <dbReference type="OMA" id="LHDVMIT"/>
    <dbReference type="OrthoDB" id="1581972at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00724">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001624">
        <property type="entry name" value="FliE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34653">
        <property type="entry name" value="PTHR34653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02049">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01006">
        <property type="entry name" value="FLGHOOKFLIE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00205">
        <property type="entry name" value="fliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="11749" checksum="4EB7F65E89631108" modified="2008-04-29" version="1">MQIGANSLLQEMKSLSGEIPTGSITPQITQQVRSTSGSDFGELLSQAVTSVGELQANSGELSSRLDMGDTRVTLSDTVIAREKASVAFEATVQVRNKLVEAYKEIMSMPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLJ5</accession>
    <name>B1KLJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobyrinic acid ac-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324266.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1634"/>
    <dbReference type="EnsemblBacteria" id="ACA85920">
        <property type="protein sequence ID" value="ACA85920"/>
        <property type="gene ID" value="Swoo_1634"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1634"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037612_0_0_6"/>
    <dbReference type="OMA" id="FKVAKNN"/>
    <dbReference type="OrthoDB" id="1370117at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02038">
        <property type="entry name" value="FlhG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033875">
        <property type="entry name" value="FlhG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="293" mass="31957" checksum="0FC7DBE362AADE46" modified="2008-04-29" version="1">MTRDQASGLRMMNQPYNDKVKVIAVSGGKGGVGKTSVSINTAVALAEKGKRVLVLDADLGLANVDIMLGLRAERNLSHVLSGDVELDDIIVRGPKGIGIIPATSGTQAMVELSSAQHAGLIRAFSEMRTQFDVLIVDTAAGISDMVLSFSRASQDVLVVVCDEPTSITDAYALIKILSREHGVFRFKIVANMVRSLREGMELFAKLSKVTDRFLDVALELVATIPFDENLRKSVRKQKLVVEAFPKSPATIAYHGLANKIISWPIPQQPGGHLEFFVERLVQKPEYQEDRASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMA3</accession>
    <name>B1KMA3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ethyl tert-butyl ether degradation EthD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322865.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0215"/>
    <dbReference type="EnsemblBacteria" id="ACA84516">
        <property type="protein sequence ID" value="ACA84516"/>
        <property type="gene ID" value="Swoo_0215"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0215"/>
    <dbReference type="HOGENOM" id="CLU_115019_1_0_6"/>
    <dbReference type="OrthoDB" id="946586at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02118">
        <property type="entry name" value="TIGR02118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12701" checksum="BD37697E533076C5" modified="2008-04-29" version="1">MIRIAISYPKTKNNNPTEQFDMDYYRERHMALVEINYLPHGLIRWELDIPQIGLGEPPVFAIGYLYFTNLQEMKNAFKQAGSIVLADIINFTNVTPIIVVSEITIMGGSHE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH4</accession>
    <name>CYSN_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfate adenylyltransferase subunit 1</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">ATP-sulfurylase large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Sulfate adenylate transferase</fullName>
            <shortName evidence="2">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cysN</name>
        <name type="ordered locus">Swoo_1687</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + H(+) + sulfate = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer composed of CysD, the smaller subunit, and CysN.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324318.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMH4"/>
    <dbReference type="SMR" id="B1KMH4"/>
    <dbReference type="STRING" id="392500.Swoo_1687"/>
    <dbReference type="PRIDE" id="B1KMH4"/>
    <dbReference type="EnsemblBacteria" id="ACA85972">
        <property type="protein sequence ID" value="ACA85972"/>
        <property type="gene ID" value="Swoo_1687"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1687"/>
    <dbReference type="eggNOG" id="COG2895">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_5_2_6"/>
    <dbReference type="OMA" id="TPYYDGP"/>
    <dbReference type="OrthoDB" id="244339at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04166">
        <property type="entry name" value="CysN_ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03695">
        <property type="entry name" value="CysN_NodQ_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04095">
        <property type="entry name" value="CysN_NoDQ_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00062">
        <property type="entry name" value="Sulf_adenylyltr_sub1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041757">
        <property type="entry name" value="CysN_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044138">
        <property type="entry name" value="CysN_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044139">
        <property type="entry name" value="CysN_NoDQ_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011779">
        <property type="entry name" value="SO4_adenylTrfase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02034">
        <property type="entry name" value="CysN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000092159" description="Sulfate adenylyltransferase subunit 1">
        <location>
            <begin position="1"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="22"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="1">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="1">
        <location>
            <begin position="89"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="1">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="1">
        <location>
            <begin position="165"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="1">
        <location>
            <begin position="202"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="110"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="165"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00062"/>
        </source>
    </evidence>
    <sequence length="469" mass="52737" checksum="F7E98DFC08B8A00E" modified="2008-04-29" version="1">MTTSSNLISSDIEEYLKVHENKDMLRVLTCGSVDDGKSTLIGRLLFDSKMIFEDQMAAIEKDSKRFNTTDDSFDLALLVDGLQSEREQGITIDVAYRYFTTEQRKFIIADTPGHEQYTRNMATGASTCDLAIILIDARHGVQVQTRRHSFICSQLGIKHVIIAINKMDAIDYDQATYQKIKKEYREFAEDLSFSDVRFVPISALKGDNVVNESPNMTWYPGSTLLKLLNTVSVEQDRSESFRFQVQYVNRPNLDFRGFCGTIGSGEIRVGDTVATLPSNKESRVKSIVTFDGELEKAVAGQAVTLTLEDEIDISRGDMLVRPHDKPFSVSHFEADVVWMTEEPLCVDREYAIKVGSKSVYGYADAINHKVDVNTLEKQSAQQLALNEIGNCHFAVTEPVQFDAYDTNRSTGSFIIIDRLTNVTVGAGMIRNPIEVKSTKAHEYSEFEIEMNALVRKHFPHWGAKDISKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMK7</accession>
    <name>B1KMK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324351.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1720"/>
    <dbReference type="EnsemblBacteria" id="ACA86005">
        <property type="protein sequence ID" value="ACA86005"/>
        <property type="gene ID" value="Swoo_1720"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1720"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_6"/>
    <dbReference type="OMA" id="KGIQQNM"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="32589" checksum="C52D212444CFDCD3" modified="2008-04-29" version="1">MDIRQLKHLDSLVKHGSFTKAAESLNMAQPALSQSIKRLELSLGVTLVTRSIKKVSLTAEGKALHSHALLIIKQLKQAESHIKSMANLTKGEVNIAVPGMLGSFYLPSRLMAFRHQYPDLKLSLFEGGTRDSLRMLIQEEVDVAIITAQDLKPEFESQLLLTEQMVVALGTEHPLAEQEDINIEQFFEHELVMFKPGYFHREWMLSQADALGLHANIGFETNLINLIKQIVSQGFAITSVLEMVISEKDEILAKPFTPPVFLDLHIAWKRHKPISVADRAFVDFLMKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMM1</accession>
    <name>B1KMM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uracil-DNA glycosylase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325735.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3128"/>
    <dbReference type="EnsemblBacteria" id="ACA87399">
        <property type="protein sequence ID" value="ACA87399"/>
        <property type="gene ID" value="Swoo_3128"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3128"/>
    <dbReference type="eggNOG" id="COG1573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075800_0_0_6"/>
    <dbReference type="OMA" id="GFCYPGK"/>
    <dbReference type="OrthoDB" id="1529383at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="30"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="23261" checksum="7C409C22AE2A7108" modified="2008-04-29" version="1">MKTDNLTNLMAQISACQLCQEELPLPAKPIIQLSSESKILIVGQAPGIRAHDHGRAFSDPSGERLRSWLGVSDEQFYDPSLFAILPMGFCFPGTIITNGKKSGDKPPLKRCAETWREALLSQLPQVELTIILGQYAIDYHLGKSAEGKKLTVTQAISQWQDYWPEYMVLPHPSPRNNLFLKKHPECEANLLPALKARVTKLIAANKNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMR3</accession>
    <name>B1KMR3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325777.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3170"/>
    <dbReference type="EnsemblBacteria" id="ACA87441">
        <property type="protein sequence ID" value="ACA87441"/>
        <property type="gene ID" value="Swoo_3170"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3170"/>
    <dbReference type="eggNOG" id="ENOG502Z7J9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1019163_0_0_6"/>
    <dbReference type="OMA" id="GQYLIFE"/>
    <dbReference type="OrthoDB" id="930343at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021246">
        <property type="entry name" value="DUF2797"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10977">
        <property type="entry name" value="DUF2797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="271" mass="30234" checksum="90F03C772D4076EF" modified="2008-04-29" version="1">MLGSIKKMRATLDDNQQVQYQLPIGDQLVEMNPLIGTSVTLTHTGKISCSNCGKKTKKSYSQGHCFVCMKKLASCDMCIMKPETCHFAQGTCREPEWGEANCFVPHYVYLSNTSGLKVGITRHTQLPTRWIDQGATQGLPILKVSTRQISGLVEVELAKMIADKTNWRTMLKGNAEAIDLKAKAAELLPEVENKIHEICMKNGEYAIEKLNEDIQDIQFPVTEFPTKISSHNFDKDPVVSGVLLGIKGQYLIFDTGVINLRKFTSYEISLS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMY1</accession>
    <name>RL23_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplW</name>
        <name type="ordered locus">Swoo_4688</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327258.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMY1"/>
    <dbReference type="SMR" id="B1KMY1"/>
    <dbReference type="STRING" id="392500.Swoo_4688"/>
    <dbReference type="EnsemblBacteria" id="ACA88938">
        <property type="protein sequence ID" value="ACA88938"/>
        <property type="gene ID" value="Swoo_4688"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4688"/>
    <dbReference type="eggNOG" id="COG0089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037562_3_1_6"/>
    <dbReference type="OMA" id="FEVDHRA"/>
    <dbReference type="OrthoDB" id="1978865at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_L23/L25_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000144606" description="50S ribosomal protein L23">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <sequence length="99" mass="10846" checksum="7083B3ED2B4F5F06" modified="2008-04-29" version="1">MISQERLLKVILAPHISEKSTVCAENDNTVVFRVAIDATKAEIKAAVAQLFEVEVDSVRTLVNKGKTKRTGARMGRRVDWKKAYVTLAAGAEIDFVGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB3</accession>
    <name>B1KNB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322959.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0309"/>
    <dbReference type="EnsemblBacteria" id="ACA84610">
        <property type="protein sequence ID" value="ACA84610"/>
        <property type="gene ID" value="Swoo_0309"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0309"/>
    <dbReference type="eggNOG" id="COG4688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_322342_0_0_6"/>
    <dbReference type="OMA" id="GSYPDDC"/>
    <dbReference type="OrthoDB" id="1169714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="898" mass="103191" checksum="4E21CB953698FDE2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNG0</accession>
    <name>B1KNG0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylsulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324383.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1752"/>
    <dbReference type="EnsemblBacteria" id="ACA86037">
        <property type="protein sequence ID" value="ACA86037"/>
        <property type="gene ID" value="Swoo_1752"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1752"/>
    <dbReference type="eggNOG" id="ENOG502ZAQ1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026635_2_0_6"/>
    <dbReference type="OMA" id="DFWDLNQ"/>
    <dbReference type="OrthoDB" id="272464at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004062">
        <property type="term" value="F:aryl sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035391">
        <property type="entry name" value="Arylsulfotran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010262">
        <property type="entry name" value="Arylsulfotransferase_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038477">
        <property type="entry name" value="ASST_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17425">
        <property type="entry name" value="Arylsulfotran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05935">
        <property type="entry name" value="Arylsulfotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767237" evidence="1">
        <location>
            <begin position="28"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Arylsulfotran_N" evidence="2">
        <location>
            <begin position="47"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="586" mass="65225" checksum="0BF0A5AFCFC89C92" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNH7</accession>
    <name>B1KNH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly PilZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324400.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1770"/>
    <dbReference type="EnsemblBacteria" id="ACA86054">
        <property type="protein sequence ID" value="ACA86054"/>
        <property type="gene ID" value="Swoo_1770"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1770"/>
    <dbReference type="eggNOG" id="ENOG5033BT2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170387_1_0_6"/>
    <dbReference type="OMA" id="GQVCRCK"/>
    <dbReference type="OrthoDB" id="1899871at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="7"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="98" mass="11336" checksum="C4051F4ABED963B6" modified="2008-04-29" version="1">MEESEDRRHSLRLDMESDKIEVSWQGEDQQLQSTDATCVDLARHGVLFEHQNSFKLGELIEISFNPDNDKRHTVKGQVCRCKNVGEFFHTAVQLVPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNH8</accession>
    <name>B1KNH8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein PsiE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1771</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PsiE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324401.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1771"/>
    <dbReference type="EnsemblBacteria" id="ACA86055">
        <property type="protein sequence ID" value="ACA86055"/>
        <property type="gene ID" value="Swoo_1771"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1771"/>
    <dbReference type="eggNOG" id="COG3223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120472_1_0_6"/>
    <dbReference type="OMA" id="HHYWPYV"/>
    <dbReference type="OrthoDB" id="2026197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009315">
        <property type="entry name" value="P_starv_induced_PsiE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020948">
        <property type="entry name" value="P_starv_induced_PsiE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37819">
        <property type="entry name" value="PTHR37819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06146">
        <property type="entry name" value="PsiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029598">
        <property type="entry name" value="PsiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="132" mass="14763" checksum="61267592C74D6C09" modified="2008-04-29" version="1">MRSIYKQYSSKGLKAVEHFVLIIIALATVVAIGQEVFHIFDVGSVALADLLLLFIYLEVLAMVANYIESGKLPVRMPLYIAIVALARYLILDMKGMSDWRIIAIAVSTLILASTVIIIRWGQLKLPYPKIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL6</accession>
    <name>B1KNL6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Acylphosphatase</fullName>
            <ecNumber evidence="3 5">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1809</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acylphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="3 5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1809"/>
    <dbReference type="EnsemblBacteria" id="ACA86093">
        <property type="protein sequence ID" value="ACA86093"/>
        <property type="gene ID" value="Swoo_1809"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1809"/>
    <dbReference type="eggNOG" id="COG1254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141932_1_1_6"/>
    <dbReference type="OMA" id="ISWCYIG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="7">
        <location>
            <begin position="7"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="95" mass="10686" checksum="7F0005D68387348A" modified="2008-04-29" version="1">MDLQMKRVLINVQGKVQGVCFRRFAQSKANELGITGYVVNNENGSVNILAQGAYPAVDNLIDWCDKGSPQAQVDKVYVQEDEENEIYLDFSILPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP2</accession>
    <name>B1KNP2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylation site containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325836.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3230"/>
    <dbReference type="EnsemblBacteria" id="ACA87500">
        <property type="protein sequence ID" value="ACA87500"/>
        <property type="gene ID" value="Swoo_3230"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3230"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098637_3_0_6"/>
    <dbReference type="OMA" id="CHVEYSS"/>
    <dbReference type="OrthoDB" id="1912524at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20469" checksum="7766332A8EF26731" modified="2008-04-29" version="1">MKLNRKQQGFTLIELVIVIIILGVLSVIATPKLLSLSSEAQASSLQGITGAIASVNKLVHSQTQIIGIADKNECLGTCNNHPNWDNEIAYFYINISGTRLYVYNGYPLSPLTAPSDSMAANNYKEVMGLSDDDFVYGMGSNSSFAIVPKKYESKLAQILAGTFKCHVEYRSPTRSFNYSIQALTDNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX7</accession>
    <name>B1KNX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327325.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4759"/>
    <dbReference type="EnsemblBacteria" id="ACA89008">
        <property type="protein sequence ID" value="ACA89008"/>
        <property type="gene ID" value="Swoo_4759"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4759"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078722_0_0_6"/>
    <dbReference type="OMA" id="FDKIDGP"/>
    <dbReference type="OrthoDB" id="1032662at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767525" evidence="1">
        <location>
            <begin position="26"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="26114" checksum="5B0A07D221386A55" modified="2008-04-29" version="1" precursor="true">MTLRPIAAVSLTALLLSACIINVNGAGRAPTEHTHQSLQLDSNGLNELVAETGAGALEIQGVVGLSHIKLEADIYTYEGIDPILTLEKRGDTARLVADFDSYKVSGNSPYIDLVVKVPAEMKMDIDDGSGSIKIQGSSADIDVKDGSGSMEIEGGKNLNIEDGSGSITLSDVNGNITLDDGSGSIEIMQVNGDVNVNDGSGSLSIKKVQGFVTIDDGSGSIDVMDTKGLKIIEAGSGSLSFDNIDGKVSLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP00</accession>
    <name>B1KP00_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4782</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327348.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4782"/>
    <dbReference type="EnsemblBacteria" id="ACA89031">
        <property type="protein sequence ID" value="ACA89031"/>
        <property type="gene ID" value="Swoo_4782"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4782"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_6"/>
    <dbReference type="OMA" id="RYQQMAL"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="181"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="242"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA89031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="445" mass="49705" checksum="6E1653920AE204EC" modified="2008-04-29" version="1">MLAIVSVKGIKPYQSSAWRITIIFSALVTLIIGTLLLGMYRQLMNEQELQTNQHLAAEKARYQQMALTLDKRSFAVQVKAADPKTALVVWRSSLDLVGALSLIPDDMPMLPKTREFPILTAGPDKLHILTGGLVMTRYGPVLIATRTDQLATLIDRFVNAAITALMLTIVLTLALGYLFSKAILRRLVQYNRLSRLIEKGEYSTRLPVSWRQDEFDMLAGKFNRVLDTLENNLLAVRGATDNIAHDLRTPLSHLRIGLEQLPDKTAQELPEACAILTEKLDHCLATFDAMLSLTRIEEGQQTLELQDFNLKVLCEDLYEMAEVMAESNEQTLSLTTSDDVEMTGDKFLLFQALFNLVDNAIKYAGEGAQIEIVQQGSEIQIRDNGPGIPDSEKERVFERLVRLDPSRHNQGTGLGLSLVKAIFARHNAQVKLMDNEPGLIVSITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP26</accession>
    <name>B1KP26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327374.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4808"/>
    <dbReference type="EnsemblBacteria" id="ACA89057">
        <property type="protein sequence ID" value="ACA89057"/>
        <property type="gene ID" value="Swoo_4808"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4808"/>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_2_1_6"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="20474" checksum="5416F7B7CC85022B" modified="2008-04-29" version="1">MATMKFLCDTKRCIECNGCVTACKNENDSALEWGIQRRRVVTINDGVPGEASISVACMHCTDAPCQAVCPANCFYKTEDGLTLHNKDTCIGCGYCLYACPFGAPQFPKKGAFGSRGKMDKCTFCAGGPEENFSDAERQKYGSNRIAEGKLPMCAELCATKSLLAGDAEIISSIFRERVAYRGSKNAIWG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP72</accession>
    <name>AROB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-dehydroquinate synthase</fullName>
            <shortName evidence="1">DHQS</shortName>
            <ecNumber evidence="1">4.2.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroB</name>
        <name type="ordered locus">Swoo_0341</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322991.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP72"/>
    <dbReference type="SMR" id="B1KP72"/>
    <dbReference type="STRING" id="392500.Swoo_0341"/>
    <dbReference type="EnsemblBacteria" id="ACA84642">
        <property type="protein sequence ID" value="ACA84642"/>
        <property type="gene ID" value="Swoo_0341"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0341"/>
    <dbReference type="eggNOG" id="COG0337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001201_0_2_6"/>
    <dbReference type="OMA" id="YGVIWDA"/>
    <dbReference type="OrthoDB" id="1677032at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0170">Cobalt</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000094620" description="3-dehydroquinate synthase">
        <location>
            <begin position="1"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="70"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="104"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="128"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="168"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <sequence length="358" mass="39174" checksum="08F1096A6121E49A" modified="2008-04-29" version="1">MKQIQVDLGVRSYPIVIGRNLMSCGEHFARFLQDKKILIVTNETVAPLYLEKLELQLSSFDCVEPVILPDGEQYKTLAQMDSIFTSLLQQNSGRDTVLIALGGGVIGDMTGFAAASYQRGIDFIQIPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQPKLVVIDTDCLSTLPAKEFSAGMAEVIKYGIIWDSEFFSWLENNVERLKTLDDEALAYAIGRCCEIKADVVAEDETEQGVRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGTVLAASTASRMGLIDGSIVCRITKLFEAFDLPVSPPDSMNFEQFIKHMRRDKKVLKGQVRLVLPEAMGQAGVYSEVSDELLEDVIRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPF6</accession>
    <name>B1KPF6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324455.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1825"/>
    <dbReference type="EnsemblBacteria" id="ACA86109">
        <property type="protein sequence ID" value="ACA86109"/>
        <property type="gene ID" value="Swoo_1825"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1825"/>
    <dbReference type="eggNOG" id="ENOG502Z9T9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1088343_0_0_6"/>
    <dbReference type="OMA" id="TTMNDEQ"/>
    <dbReference type="OrthoDB" id="1039997at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="28476" checksum="F440FC99A4AFC838" modified="2008-04-29" version="1">MNNLIEITAAEIKQLADVEPQQASKKFELMANTMTDEVLVEVIEHMDIVTLTQINSHHDISCPSIMSELMSPEQIRDIVCQQPLYWEEKIKSNADELSQHTFDFLTYLIRIQDSEAKQVAILECIAEDPAGLFYLSIPFIELILGPSTDTDVQINDTYDDEDDGETIGFSDRSAEEEAHSLSIDDPRSLLALIREIAPDVEKSIKNLLRSENSGWMNIINKFVSELVIQAKEKNQVADEYAEVDDMFSFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPJ4</accession>
    <name>B1KPJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cob(II)yrinic acid a,c-diamide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324493.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1863"/>
    <dbReference type="EnsemblBacteria" id="ACA86147">
        <property type="protein sequence ID" value="ACA86147"/>
        <property type="gene ID" value="Swoo_1863"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1863"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_3_1_6"/>
    <dbReference type="OMA" id="FMQPWDF"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02145">
        <property type="entry name" value="BluB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012825">
        <property type="entry name" value="BluB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02476">
        <property type="entry name" value="BluB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="24833" checksum="21051EAB4CB1CC31" modified="2008-04-29" version="1">MKITENERDAVYKTIFARRDVRGEFSSEPIPEDVLHRVLTAAHHAPSVGFMQPWDFVLVNELETKKKIKAGFDSANHESAEQFNDDKAVQYRQLKLEGILEAPLGICVTCDRHRNGPTVLGRTIKAEMDLYSSVCAVQNLWLAARAENLGVGWVSILHDSVLRDALNIPEEIEIIAYLCVGYVSHFKDKPELETLGWQPRRDVNSAIHYGTWSRSADTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPL5</accession>
    <name>B1KPL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1884"/>
    <dbReference type="EnsemblBacteria" id="ACA86168">
        <property type="protein sequence ID" value="ACA86168"/>
        <property type="gene ID" value="Swoo_1884"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1884"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_773612_0_0_6"/>
    <dbReference type="OMA" id="AMLDESC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="56"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="248"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="332" mass="36945" checksum="28F83E5121DE01BA" modified="2008-04-29" version="1">MKVNPDFFPLTQLATRFVDQLAQCRRLNLRVHEASEHHVLIELPYAHELVGYPDTGVIHGGVITTLMDTASGSAVVCSIFDKYQALELSPTLDLRVDYMKPADPNKPVYGFAECYKISSSVAFTRGIAYQDSIDDPIAHAVGSFMRISPEMIGDEFRQALIGEEVTSLSDALPDSEQCVQEPIVATAPQLDVKEIVKKATELNDFSHLLSHVPYTDFIGMSVERFGDELVFRLPAKDDNIGNPILPAIHGGVIAGFMEMSAIVQLMVFMHTSKVPKVVDFSIDYLRAGYHKDTFAECKITRQGRRVANVSINCWQTNRKKLIATARAHFLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM2</accession>
    <name>B1KPM2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative NAD(P)H nitroreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1891</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324521.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1891"/>
    <dbReference type="EnsemblBacteria" id="ACA86175">
        <property type="protein sequence ID" value="ACA86175"/>
        <property type="gene ID" value="Swoo_1891"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1891"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_5_0_6"/>
    <dbReference type="OMA" id="IPEWEQV"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02135">
        <property type="entry name" value="YdjA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026021">
        <property type="entry name" value="YdjA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000232">
        <property type="entry name" value="YdjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 3" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="4">
        <location>
            <begin position="17"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="131"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="182" mass="19185" checksum="55CC8A030A9F2FD0" modified="2008-04-29" version="1">MDAIELLLTRQSCPRLAEPGPSEAQLNTILDAGVRVPDHAGLAPWEFIIAQGEGLKKLGQVFADAAMSSGADEAALAKALVMPQRAPLVIVVVAKPVEHAKVPELEQHIAAGCATMAMQQAAFASGLGAIWRTGSYAFDRNVHQSLGLTQGDQIVGFLYVGTPVVKAPIKAAKKGGEFTRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPR6</accession>
    <name>B1KPR6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325935.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3330"/>
    <dbReference type="EnsemblBacteria" id="ACA87599">
        <property type="protein sequence ID" value="ACA87599"/>
        <property type="gene ID" value="Swoo_3330"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3330"/>
    <dbReference type="eggNOG" id="ENOG5033BAR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_209702_0_0_6"/>
    <dbReference type="OMA" id="NNSEDTM"/>
    <dbReference type="OrthoDB" id="2047066at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="61" mass="6951" checksum="2C0B6C1C84C23FDC" modified="2008-04-29" version="1">MAKFFLLPIILCLFWTLFLHFNGVPIKQGKKGFIYIIAISATIILSLGLLLWITAEQNIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPU5</accession>
    <name>B1KPU5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3359</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325963.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3359"/>
    <dbReference type="EnsemblBacteria" id="ACA87628">
        <property type="protein sequence ID" value="ACA87628"/>
        <property type="gene ID" value="Swoo_3359"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3359"/>
    <dbReference type="eggNOG" id="COG0497">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018297_3_1_6"/>
    <dbReference type="OMA" id="QVICVTH"/>
    <dbReference type="OrthoDB" id="1074831at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="553" mass="61217" checksum="23109B3704C35004" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW3</accession>
    <name>B1KPW3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325981.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3377"/>
    <dbReference type="EnsemblBacteria" id="ACA87646">
        <property type="protein sequence ID" value="ACA87646"/>
        <property type="gene ID" value="Swoo_3377"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3377"/>
    <dbReference type="eggNOG" id="ENOG503311J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125332_0_0_6"/>
    <dbReference type="OMA" id="NGPIRRE"/>
    <dbReference type="OrthoDB" id="1821477at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17859" checksum="5DA92A8358C60047" modified="2008-04-29" version="1">MTFLIMTVDNMREVEQVTIIGNTQDTALWIWENLVPKSGRAASAQGEVMRCIELLAWEAQNNSNLNWNKSFDDILAYLKETYLGDTSPMSAFFDENTKSQIESDLHRLGHFILPTELDSRVYNEELPYIEEDLYARLTENLVSFCRQYPSLLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW8</accession>
    <name>B1KPW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325986.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3382"/>
    <dbReference type="EnsemblBacteria" id="ACA87651">
        <property type="protein sequence ID" value="ACA87651"/>
        <property type="gene ID" value="Swoo_3382"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3382"/>
    <dbReference type="eggNOG" id="COG3064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024625_5_0_6"/>
    <dbReference type="OMA" id="QWVAPIA"/>
    <dbReference type="OrthoDB" id="1637190at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021728">
        <property type="entry name" value="DUF3300"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40269">
        <property type="entry name" value="PTHR40269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11737">
        <property type="entry name" value="DUF3300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="488" mass="57688" checksum="6F09D528319CECFA" modified="2008-04-29" version="1" precursor="true">MNTLKSRLQSSRFTTFISYLILLIASSIPVANAQAVEEQVQFSEAELEQMLAPIALYPDSLLTHILIAATYPLELVQANRLVNKNKLLPTAQLMEKAQKKDWDPSVTALLAFPNVLEKLSSDLSWTQDLGDAFLQDEAQMLASIQSLRAQADEANSLANMENMSVTRVNKQIVIEPVQKEIVYVPYYDPRTVYGHWRWYNYPPVYWAPYPYYVGRPHDHFYWNSGVHISFNFFFSAFHWSNHRVVVIDHRHSRHYRHRGRIVTSHGSQKWHHKPHHRRGVAYRSTHVKQRYNSHRPSIAHSKQLRHAERNSLAHNRKHKSRHDKTLKHYNKQVKQHREQRFTSKLHNSHKPVKSHRPIKSHQPVKSPQRIKSHQPVRNHKPSHYDRKERHDTASTHNRVKSQLKSRERTQREVKKSQTQRSIHQPRNQQAQRSMDKQQRQSTQRMRTQQPKQARQSTQRAQKSTQQRAHRSAQQRSQHKGQKQNRSRD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ35</accession>
    <name>ATPG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpG</name>
        <name type="ordered locus">Swoo_4899</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327465.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ35"/>
    <dbReference type="SMR" id="B1KQ35"/>
    <dbReference type="STRING" id="392500.Swoo_4899"/>
    <dbReference type="EnsemblBacteria" id="ACA89148">
        <property type="protein sequence ID" value="ACA89148"/>
        <property type="gene ID" value="Swoo_4899"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4899"/>
    <dbReference type="eggNOG" id="COG0224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050669_0_1_6"/>
    <dbReference type="OMA" id="MQITSAM"/>
    <dbReference type="OrthoDB" id="1701531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0139">CF(1)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000134207" description="ATP synthase gamma chain">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <sequence length="286" mass="31528" checksum="49A81C6ED2039FF9" modified="2008-04-29" version="1">MANAKEIKTKIASVQNTQKITSAMEMVAASKMRKAQDRMASSRPYAENMRKVIGHVAQGSLEYKHPYLEVREAKRVGYIVVSTDRGLCGGLNVNLFKKVVADVKKQREAGAEVEFCPIGARSVQFFNSFGGQVSAHASGLGDAPKLADLIGTVRVMLQAYNEGKLDRLYVVFNKFVNTMSQTPVIEQLLPLPKSEEDEISHHWDYLYEPDPKELLDTLLVRYVESQVYQGVVENIASEQAARMVAMKAATDNAGELISDLELVYNKARQAAITQELSEIVSGAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ52</accession>
    <name>B1KQ52_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine or other phosphorylase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327481.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4916"/>
    <dbReference type="EnsemblBacteria" id="ACA89165">
        <property type="protein sequence ID" value="ACA89165"/>
        <property type="gene ID" value="Swoo_4916"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4916"/>
    <dbReference type="eggNOG" id="COG0775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031248_1_0_6"/>
    <dbReference type="OMA" id="ILVQGAM"/>
    <dbReference type="OrthoDB" id="1860206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="35"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="31194" checksum="D3BA09C979824564" modified="2008-04-29" version="1">MPTHEQLLTEKLHSEHLNQQKPDTVKLTTEMQNPILVQGAMDVEVENLVAALGDVKQKTFGSWTFWEGLLDGYPVVVSRTEIGLANAAASTTLGIEHYQPKVIINQGTSGGHDPKLFRSDIVIGETSFNMGAYKIEFVEKGQGIHPTTWQNFDMPMYLRENGVVVEHNHFKADPTLVEIALSQASSYTQGKVVVGRIGSCDEWNREVDRINWFHETMGTSVEEMETSAAAQVAEAYKLPFVSIRVLSNTDQHKQDFEPQTAIDCQVYVLDVIKALIKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE3</accession>
    <name>B1KQE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Restriction modification system DNA specificity domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0501</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323147.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0501"/>
    <dbReference type="REBASE" id="17470">
        <property type="entry name" value="S.SwoAI"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84798">
        <property type="protein sequence ID" value="ACA84798"/>
        <property type="gene ID" value="Swoo_0501"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0501"/>
    <dbReference type="eggNOG" id="COG0732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021095_10_4_6"/>
    <dbReference type="OMA" id="LMARCDE"/>
    <dbReference type="OrthoDB" id="827072at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="124"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="446"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="612" mass="68117" checksum="3B06BEF86E097336" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT1</accession>
    <name>B1KQT1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3419"/>
    <dbReference type="EnsemblBacteria" id="ACA87687">
        <property type="protein sequence ID" value="ACA87687"/>
        <property type="gene ID" value="Swoo_3419"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3419"/>
    <dbReference type="HOGENOM" id="CLU_1073234_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766963" evidence="1">
        <location>
            <begin position="36"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="259" mass="29384" checksum="A5F1BE21193DE89D" modified="2008-04-29" version="1" precursor="true">MNGFMISTVYNSNTQRHSLLCLLSAMMLSISNASAQTLPQESLLGQICYGDGDEQKISADTAIWLARMIDGETYGHPTEVEANTMLWAIAQLSAVRKTKRNLTWKLDKLAQLYSQPINHKWTRSGRKCKRYYAKDFDGKIPGNCSKKKVKRRENNRSKPWNELAPIARQSVLKFAKGDSINPAIGVQGWYASGLWYRRDKKNINAREHKLFHSKIDNNVFYTRTKSPATNNWDGFEVTIVAADSFCPMIIDLPSKQGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT5</accession>
    <name>B1KQT5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3423</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326026.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3423"/>
    <dbReference type="EnsemblBacteria" id="ACA87691">
        <property type="protein sequence ID" value="ACA87691"/>
        <property type="gene ID" value="Swoo_3423"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3423"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056916_1_0_6"/>
    <dbReference type="OMA" id="FWTAQCV"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="8"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="42171" checksum="A73D077F0DF46164" modified="2008-04-29" version="1" precursor="true">MMRNKISLTLLSFLANFIMAGFATQFGMLIEPIAEKFSANINEVASIFSLLNGGALAGTIAAFFLIEKVGVKRITLISYMLIAISAASLHFTSSLSVVMIAMMLIGLCGGVGLCIAGTIVVSVWKDKIQSTILVVQDATFNVAGVVFPLITTYALSNALNWSYSYLAVGLVALITANVTLLTNFDLCEPKSDASGCKIGEKSEWNFSIISAGIGLFLGMLALYTFLTWAPMFVKEKFDIPFEEAGNIITQYWSAALVGALVSTLIVSRVKIQHFLMGMMTLALVITSIIVTTDKLEWMGYLTYGYGFTCAALYNAFIAYGVSFVKQASSKNVSYILISGSAGAMFSPAISAMFETIIGLQSVMYAIPVIYAIILTMLVVSRRQAAENSLAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQW2</accession>
    <name>B1KQW2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3450</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the system for phosphate transport across the cytoplasmic membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326053.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3450"/>
    <dbReference type="EnsemblBacteria" id="ACA87718">
        <property type="protein sequence ID" value="ACA87718"/>
        <property type="gene ID" value="Swoo_3450"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3450"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026228_6_0_6"/>
    <dbReference type="OMA" id="FKKKALC"/>
    <dbReference type="OrthoDB" id="1222928at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5027155849" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="36"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="34638" checksum="F63955304C68F7BA" modified="2008-04-29" version="1" precursor="true">MKLKQLVGAVSLTAASVFSATSMAAIDQSLPVYEKSSGVSGNLSSVGSDTLANMMTLWAEEFKEMYPNVNIQIQAAGSSTAPPALTEGTSQFGPMSRKMKPNEMEAFEKHYGYQPTAIRVAIDALAVFVHKDNPIEGLSIEQIDDIFSATHKCGGSDVKRWGDVGLTGSWSAKDVQLYGRNSVSGTYGYFKKKALCKGDFKANVNEQPGSASVVQSVSQSLNAIGYSGIGYKTAGVKAVAISKKGTKYIEATAANAASGTYPLSRYLYVYVNKHPNKDLAPMDREFLKFALSKQGQQIVEKDGYVPLPRSVTAKDLAKAGIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQY4</accession>
    <name>B1KQY4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">OmpA/MotB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3474</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MotB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326074.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3474"/>
    <dbReference type="EnsemblBacteria" id="ACA87740">
        <property type="protein sequence ID" value="ACA87740"/>
        <property type="gene ID" value="Swoo_3474"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3474"/>
    <dbReference type="eggNOG" id="COG1360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016890_0_3_6"/>
    <dbReference type="OMA" id="AFSEMDV"/>
    <dbReference type="OrthoDB" id="1619550at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025713">
        <property type="entry name" value="MotB_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13677">
        <property type="entry name" value="MotB_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="7">
        <location>
            <begin position="190"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="107"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="110"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="322" mass="35134" checksum="B6D8412AA5487485" modified="2008-04-29" version="1">MAKQKCDCPPPGAPLWLATFADLMSLLMCFFVLLLSFSEMDVLKFKQIAGSMKYAFGVQNKVEVKDIPKGTSVIALEFRPGRPEPTPIETITQQTSEITEPVIEYQAGEDDSSGGSQKQQGQQRGGESSATAQEQSVAQSSSDSESEAKAKEESDAQAAAQENINEQVKKMAQELNTEIVDGAIEIESLGQQIIIRIREKGAFSSGSGFLQPRFKPVVRRVGELLKDVPGIVTVSGHTDDMNISNELYSSNWDLSSKRAVAVAHELIKVKGFDPQRMKVVGMANSDPLVANDTSSHRARNRRVEIAIEQGKAMESDEITVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR06</accession>
    <name>B1KR06_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis accessory factor UbiJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiJ</name>
        <name evidence="3" type="ordered locus">Swoo_0526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323171.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0526"/>
    <dbReference type="EnsemblBacteria" id="ACA84823">
        <property type="protein sequence ID" value="ACA84823"/>
        <property type="gene ID" value="Swoo_0526"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0526"/>
    <dbReference type="eggNOG" id="COG3165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100130_2_0_6"/>
    <dbReference type="OMA" id="LELDWEY"/>
    <dbReference type="OrthoDB" id="1959286at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032150">
        <property type="term" value="P:ubiquinone biosynthetic process from chorismate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02215">
        <property type="entry name" value="UbiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038989">
        <property type="entry name" value="UbiJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38693">
        <property type="entry name" value="PTHR38693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="SCP2" evidence="2">
        <location>
            <begin position="17"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="23419" checksum="E9E9ECF01454BCE5" modified="2008-04-29" version="1">MKREFALLLSAALETALKQVIAQSPDEYAKLRSLHGKVLCIQLSQLSWPIYLIFAKEIQVLGKYEGEVTTKVNADITTLYQLTEGANLTELIKQDKLSLEGDLNLLQTFSHFLQKVEFDFAEPLSKYIGDAPTHMLITGIEQAKNDITHIFRQSRSHVGQLTTEEYKLAPHAIEFVYLGDRIDDLVADIDAIEKRINNLQSRAKTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR08</accession>
    <name>B1KR08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arginase/agmatinase/formiminoglutamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323173.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0528"/>
    <dbReference type="EnsemblBacteria" id="ACA84825">
        <property type="protein sequence ID" value="ACA84825"/>
        <property type="gene ID" value="Swoo_0528"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0528"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_796519_0_0_6"/>
    <dbReference type="OMA" id="ALGYYHV"/>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="344" mass="37275" checksum="FD8D464E25BC6E76" modified="2008-04-29" version="1">MQYLLPFTSQHCRQLVTAREGETKLAQTVLTHDENAVLKETLAKAKLKGARFAIFGIGEDIGPRANLGRGGATDAFEAAMAQFLNLQSNRFFDGKSCLVLGQIKTDDLQLSEEAATQSLRANVEQLDTRVIEIAEQVMQAGLEPIVIGGGHNNAYGLLMAAKQSHNKKVAAVNLDPHSDFRPREGRHSGNGFSYAAASEALGYYHVLGMHELKNSEETLDQLSSFGGGWHTLQSTWIRREVSLASALEEIVTKLNNSQLPVALELDLDAITNMPSSASTAAGIPLLDALHYVYTVARHTPCAYLHLAEAAPSCHVAGLQAGYRETGQSISELIYAYIQGRGQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR10</accession>
    <name>B1KR10_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator of ribonuclease activity A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rraA</name>
        <name evidence="3" type="ordered locus">Swoo_0530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RraA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323175.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0530"/>
    <dbReference type="EnsemblBacteria" id="ACA84827">
        <property type="protein sequence ID" value="ACA84827"/>
        <property type="gene ID" value="Swoo_0530"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0530"/>
    <dbReference type="eggNOG" id="COG0684">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072626_4_0_6"/>
    <dbReference type="OMA" id="RSCDTQF"/>
    <dbReference type="OrthoDB" id="1614890at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060698">
        <property type="term" value="F:endoribonuclease inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00471">
        <property type="entry name" value="RraA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010203">
        <property type="entry name" value="RraA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014339">
        <property type="entry name" value="RraA_gpbac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="SSF89562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01935">
        <property type="entry name" value="NOT-MenG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02998">
        <property type="entry name" value="RraA_entero"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="17103" checksum="E5735B4BA87DAF45" modified="2008-04-29" version="1">MEYNTSELCDTYIDVVDVVEPMFSNYGGCNSFGGSISTIKCFEDNGLIIEALQNDGEGRVLLVDGGGSLRRALIDASIAQVAVDNNWEGIIVYGSVRDVDALEDLDIGIQAMASIPVGADSNSVGELEIPVNFGGVTFLPLDHVYADNTGIILSPEPLDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX7</accession>
    <name>B1KCX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome-c peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0005</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="6">Binds 2 heme groups.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Binds 2 heme groups per subunit.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.5" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322655.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0005"/>
    <dbReference type="PeroxiBase" id="4991">
        <property type="entry name" value="SwoDiHPOX"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84306">
        <property type="protein sequence ID" value="ACA84306"/>
        <property type="gene ID" value="Swoo_0005"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0005"/>
    <dbReference type="eggNOG" id="COG1858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034652_3_1_6"/>
    <dbReference type="OMA" id="CGFCHIQ"/>
    <dbReference type="OrthoDB" id="52724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023929">
        <property type="entry name" value="Di-heme_enz_MXAN0977"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026259">
        <property type="entry name" value="MauG/Cytc_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000294">
        <property type="entry name" value="Cytochrome-c_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04039">
        <property type="entry name" value="MXAN_0977_Heme2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="213"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="395" mass="44315" checksum="1D9AFAFD13FB831E" modified="2008-04-29" version="1" precursor="true">MNKLIWLGLLVFSIPLIYLATTLSQPEPKSDYRWPLAQGFPKPQVPESNPMSQAKVELGRYLFYDKALSANQTQSCASCHIQSLAFSEAKPVSVGSTGEFHRRNSPGLINIAYNKTLTWAHDGLTDIEQQLLLPIFGENPIELGAIGHEDEILARLQRSPYPELFKQAFPNTKSEVDFVQVTQALSSFVRSLLSLNSPFDRYAYQGQDEALNTQELAGMDLFFSERLECHHCHGGFNFTQSTSHEKQPLDKRPFHNTGLYYTERPSLASTSGTMTQNLGYPEKDRGLAEITINPMDDGRFRAPSLRNIALTAPYMHDGSVVTLEEVLEIYAAGGRNITDGDYQGDGRLNPLKSPFIKGFTLTDKEKEQLLAFLHSLTDEEFINNPAFSDPWLDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD09</accession>
    <name>B1KD09_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Der GTPase-activating protein YihI</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yihI</name>
        <name evidence="4" type="ordered locus">Swoo_0055</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with Der.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YihI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322705.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0055"/>
    <dbReference type="EnsemblBacteria" id="ACA84356">
        <property type="protein sequence ID" value="ACA84356"/>
        <property type="gene ID" value="Swoo_0055"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0055"/>
    <dbReference type="eggNOG" id="COG3078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094104_3_0_6"/>
    <dbReference type="OMA" id="ENNECLN"/>
    <dbReference type="OrthoDB" id="2068666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01058">
        <property type="entry name" value="GAP_YihI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007336">
        <property type="entry name" value="YihI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04220">
        <property type="entry name" value="YihI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="20121" checksum="62B6F400B4ACDB64" modified="2008-04-29" version="1">MAHSKKSRKANENSPKLAPRTKKNERVLSGKKKDTGNKAGSRHNKKVVGSVNGTATQKKDPRHGSKVAVKLDLPSKVVAPKKEKGPKLTDEQKLLKLEDDPRLNQLLDMLEEGRELPQDDQKWLEKQLNQIEALMERLGITEEDDLEHVMKSVTNSDDDLFDKFESGADLLKDFQNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD90</accession>
    <name>B1KD90_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3663</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326258.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3663"/>
    <dbReference type="EnsemblBacteria" id="ACA87925">
        <property type="protein sequence ID" value="ACA87925"/>
        <property type="gene ID" value="Swoo_3663"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3663"/>
    <dbReference type="eggNOG" id="COG1087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_6"/>
    <dbReference type="OMA" id="QMVESAW"/>
    <dbReference type="OrthoDB" id="1597849at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="5"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="336" mass="36914" checksum="1FD3F0B704C2B28A" modified="2008-04-29" version="1">MDKILVTGGMGYIGSHTCLALLESGFEPVIFDNLSNSSAGVLQQIYTISGQMLSFVEGDIRDTALLQQVLIKHQCVAVIHFAALKAVGESTEQPHRYYDNNVGGTLSLLKAMEESAVRNIVFSSSATVYGDPDYIPIDESHPIRATNPYGWSKVMVEQILRDTCASIANWQAISLRYFNPVGAHDSGLLGENPMGTPNNLMPYIAQVAVGKRDFLQVFGDDYPTDDGTGVRDYIHVMDLAAGHVHALQGKRGVKGFYAYNLGTGQGYSVLEMVNSFSKESGQAIPYRIADRRSGDIPCSYADPSLAQHELDWQASRDLTQMTADVWRWQSKYPMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG6</accession>
    <name>B1KDG6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323314.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0671"/>
    <dbReference type="EnsemblBacteria" id="ACA84967">
        <property type="protein sequence ID" value="ACA84967"/>
        <property type="gene ID" value="Swoo_0671"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0671"/>
    <dbReference type="eggNOG" id="ENOG5032XB1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114930_1_0_6"/>
    <dbReference type="OMA" id="MVTAYQG"/>
    <dbReference type="OrthoDB" id="1673363at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="19259" checksum="34EB65005D257BF7" modified="2008-04-29" version="1" precursor="true">MERRTFLTTALVGTATLALGLSVYSPEHIRVNKALDSEHRLLFSVLLPVFLEDALPNVETTRVAAQNRTLDAIAETISHLPQEGQAELEQLLDMLEQRLGLLVLTGSMTPLMMRSPDELISMLEYWRNSFIDLMVTAYQGLRELVMASYYACPEHWSRLHYAKPTYFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL7</accession>
    <name>B1KDL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YebG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324759.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2130"/>
    <dbReference type="EnsemblBacteria" id="ACA86414">
        <property type="protein sequence ID" value="ACA86414"/>
        <property type="gene ID" value="Swoo_2130"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2130"/>
    <dbReference type="eggNOG" id="COG3141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146554_1_0_6"/>
    <dbReference type="OMA" id="MAVITKF"/>
    <dbReference type="OrthoDB" id="1930646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009813">
        <property type="entry name" value="Uncharacterised_YebG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038627">
        <property type="entry name" value="YebG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07130">
        <property type="entry name" value="YebG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="94" mass="10449" checksum="3D0DC90B02DB20F7" modified="2008-04-29" version="1">MAVITKFVVVREGVEKMTFTSKKEADAYDKMLDIADQLTPFVANSELELDDNVCEKLAFYMAQNKDELFSLLKGVAPSAAKTAKKSPKKAETKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDN9</accession>
    <name>B1KDN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="13">5.4.3.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_2152</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324781.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2152"/>
    <dbReference type="EnsemblBacteria" id="ACA86436">
        <property type="protein sequence ID" value="ACA86436"/>
        <property type="gene ID" value="Swoo_2152"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2152"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051314_2_1_6"/>
    <dbReference type="OMA" id="WSMVYYL"/>
    <dbReference type="OrthoDB" id="1702107at2"/>
    <dbReference type="UniPathway" id="UPA00621"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="185" mass="20839" checksum="F0AFABB90B189839" modified="2008-04-29" version="1">MPFNIPIALTLFRLFLLPVFVVIFYLPYSWSPFFAAFVFWLAAVTDALDGYAARKLKQSTRFGAFLDPVADKIMVTTALVLLVAEYNSIWMTLPALFMIGREIVISALREWMAEIGKRGSVAVSWIGKYKTAAQMTAITGLIWHPNDLITYAAYALFYVAAVLTFWSMMSYIMAAWSDLTAESNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDW4</accession>
    <name>B1KDW4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsfS</name>
        <name evidence="3" type="ordered locus">Swoo_3706</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326298.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3706"/>
    <dbReference type="EnsemblBacteria" id="ACA87966">
        <property type="protein sequence ID" value="ACA87966"/>
        <property type="gene ID" value="Swoo_3706"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3706"/>
    <dbReference type="eggNOG" id="COG0799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092688_6_1_6"/>
    <dbReference type="OMA" id="VVHVFQK"/>
    <dbReference type="OrthoDB" id="1990650at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="12300" checksum="8B73F2506587F2D1" modified="2008-04-29" version="1">MESAELKLFVTDKVEDLKAKDIVVLDISERSNLADFMVVCSGTSKTHVKAIAENLVVEAKRANLHINGVEGRESSEWVLVDLGDVILHVMQDKTRDFYELEKLWTEKPA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX2</accession>
    <name>LIPB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Octanoyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lipB</name>
        <name type="ordered locus">Swoo_3714</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326306.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDX2"/>
    <dbReference type="SMR" id="B1KDX2"/>
    <dbReference type="STRING" id="392500.Swoo_3714"/>
    <dbReference type="EnsemblBacteria" id="ACA87974">
        <property type="protein sequence ID" value="ACA87974"/>
        <property type="gene ID" value="Swoo_3714"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3714"/>
    <dbReference type="eggNOG" id="COG0321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035168_3_1_6"/>
    <dbReference type="OMA" id="GEVTYHC"/>
    <dbReference type="OrthoDB" id="1806796at2"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000089476" description="Octanoyltransferase">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="BPL/LPL catalytic" evidence="2">
        <location>
            <begin position="32"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="71"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="138"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01067"/>
        </source>
    </evidence>
    <sequence length="219" mass="24494" checksum="D4E35D9533E2CF4C" modified="2008-04-29" version="1">MSESTLHVRYLGQQDYESVWHAMQEYTDNRDSSSPDQLWIVEHPPVFTQGQAGKSEHILNPGDIPVIQVDRGGQVTYHGPGQLVAYPLINIKRLKIGVRQLVTDIENSIVQMLENYQVKAYAKADAPGVYVDERKVASLGLRIRKGCSFHGLALNVDMDMSPFQRINPCGYAGLEMVQCKQLGGPQTVEEAGEQLVKTFSHNLGYQNLVHHQGLSQSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE9</accession>
    <name>B1KEE9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324870.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2246"/>
    <dbReference type="EnsemblBacteria" id="ACA86527">
        <property type="protein sequence ID" value="ACA86527"/>
        <property type="gene ID" value="Swoo_2246"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2246"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_75_6"/>
    <dbReference type="OMA" id="ERYMQRS"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="390"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="499"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="736"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="444"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="854" mass="95995" checksum="7F5EC68847389815" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEM1</accession>
    <name>B1KEM1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3777</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3777"/>
    <dbReference type="EnsemblBacteria" id="ACA88036">
        <property type="protein sequence ID" value="ACA88036"/>
        <property type="gene ID" value="Swoo_3777"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3777"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_69_6"/>
    <dbReference type="OMA" id="VATHRYC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="440"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="701" mass="78856" checksum="38BBDE2E228A1040" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU0</accession>
    <name>B1KEU0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326435.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3847"/>
    <dbReference type="EnsemblBacteria" id="ACA88105">
        <property type="protein sequence ID" value="ACA88105"/>
        <property type="gene ID" value="Swoo_3847"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3847"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070319_2_0_6"/>
    <dbReference type="OMA" id="GEKTGFW"/>
    <dbReference type="OrthoDB" id="1152952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766997" evidence="1">
        <location>
            <begin position="27"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="55"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="255" mass="27818" checksum="6A9252CACE78E34F" modified="2008-04-29" version="1" precursor="true">MKNLFKTISVLLFVASSLFGASSVYAEGPKRVLIVMSSESAMGISGKLTGTWFEEVATPYYTLRKEGYEVVMASLEGGDAPIDLLSMQAPFTTPNTDKFLNDIVAMHALENTNKLSEINPDDFDALFFPGGYGLLWDLASDSMTIKMIEDFYAANKPIAMVCHAPAILRDAKKANGEPLVKGLTVTGFMNAEDDELDLSRHLLFSLEDMLKANGGNYKKTKKNWVAHIEIDGPLMTGQNPASAPVLAKALAKRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF13</accession>
    <name>B1KF13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, GNAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323511.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0870"/>
    <dbReference type="EnsemblBacteria" id="ACA85164">
        <property type="protein sequence ID" value="ACA85164"/>
        <property type="gene ID" value="Swoo_0870"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0870"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118082_0_0_6"/>
    <dbReference type="OMA" id="QYGPIWI"/>
    <dbReference type="OrthoDB" id="1826274at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="49"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="20687" checksum="31752AC2029D6715" modified="2008-04-29" version="1">MKTRLALSGDVEELEKLERLYQNDELGDASQAGGFDGQVFGSKDLRNLIEKGWIVVAEEKQVILGYVIAGPWPLFETGPVYRHILARLQRVEFGSAKLTKTNSCQYGPIWIHPEYRGQGTFELLVSTLKEHVRAKYPFMITFIAEDNMISFSAHTNKASMQVLDFFTFDDRDYYLLVLPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF31</accession>
    <name>B1KF31_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidine kinase</fullName>
            <ecNumber evidence="1">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0888</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323529.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0888"/>
    <dbReference type="EnsemblBacteria" id="ACA85182">
        <property type="protein sequence ID" value="ACA85182"/>
        <property type="gene ID" value="Swoo_0888"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0888"/>
    <dbReference type="eggNOG" id="COG3852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_371269_0_0_6"/>
    <dbReference type="OMA" id="YETRREY"/>
    <dbReference type="OrthoDB" id="126854at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="360"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="610"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="738" mass="83443" checksum="DCEFD3EB711112B2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF76</accession>
    <name>B1KF76_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ntox15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324959.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2338"/>
    <dbReference type="EnsemblBacteria" id="ACA86617">
        <property type="protein sequence ID" value="ACA86617"/>
        <property type="gene ID" value="Swoo_2338"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2338"/>
    <dbReference type="eggNOG" id="ENOG5032BY1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_447524_0_0_6"/>
    <dbReference type="OrthoDB" id="581675at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028949">
        <property type="entry name" value="Ntox15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15604">
        <property type="entry name" value="Ntox15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ntox15" evidence="2">
        <location>
            <begin position="511"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="669" mass="72172" checksum="EF4183D75FAB04FC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFA3</accession>
    <name>B1KFA3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choloylglycine hydrolase</fullName>
            <ecNumber evidence="5">3.5.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.24" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324986.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2365"/>
    <dbReference type="MEROPS" id="C59.001"/>
    <dbReference type="EnsemblBacteria" id="ACA86644">
        <property type="protein sequence ID" value="ACA86644"/>
        <property type="gene ID" value="Swoo_2365"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2365"/>
    <dbReference type="eggNOG" id="COG3049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045206_1_2_6"/>
    <dbReference type="OMA" id="MCTRLVY"/>
    <dbReference type="OrthoDB" id="636485at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045302">
        <property type="term" value="F:choloylglycine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764373" evidence="3">
        <location>
            <begin position="21"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="CBAH" evidence="4">
        <location>
            <begin position="21"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="362" mass="40453" checksum="6FB335F07F87E547" modified="2008-04-29" version="1" precursor="true">MKKTLIAILLTSISLPQASACTGISLTSTNHDYIQARTIEWGHSDLNSKLIISPRDYRYTSTMPDQQTGLSWKSRYGFTGISVSDDRYIAEGINEKGLSAGLFYFKGYGSLADFDPKKVDNNIVDMDFVRWMLTQFKTVDEVTKALESIKLVTVFIDEKGQPSPTAHWRVADKQGNAIVVEIMNKGEVHIHKNSAKVLTNSPDYPWQVTNLNNYIHLQPGSSAPQKINGVDAFSFGVGSSFIGLPGDISPPSRFVRAAFYVNSAPEMSNSDQAVSQAFHILNNFDIPIGSEFSPQYKAHIPNLPSATQWTSVIDQTNGYLFYKTMNDSRIKRVDLNKLDFSGDKEIKRQLDDGKFTFEDVIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFA6</accession>
    <name>B1KFA6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2368"/>
    <dbReference type="EnsemblBacteria" id="ACA86647">
        <property type="protein sequence ID" value="ACA86647"/>
        <property type="gene ID" value="Swoo_2368"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2368"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_2_2_6"/>
    <dbReference type="OMA" id="HCIDNGV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766527" evidence="1">
        <location>
            <begin position="40"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="94"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="441" mass="47345" checksum="E218EB9E65114A95" modified="2008-04-29" version="1" precursor="true">MEASMKTTEKIRKIIIKRFPKRLAITALLSLGIHMPLFAQDTLLIADGYIDVVKGKTVKDVVIVVSGNKIIKVTEQDKLTDRTAYKIIDLSGKTLVPGVMDMHVHLAGDAEDDFLAAQNYSIPRQTVKAVKNAKLTLLAGFTTVRDLGASGYTVIATRDGINAGEIPGPRVWAVGNPISITGGHCDDNFSAPEKLSIAGGVADGPWAVRAKVRENIKYGANAIKVCATGGVFSKGTKVGVQQLTYEEIKAAVDEAHMRGLTIAAHAHGTSGIKASIKAGIDSIEHCSFMDKEAIKMAIKAGTYLSCDIYNTEYTLAFGAENGVPEENINKEKQVSKAQRESFRQAVKAGANMVFGSDAAIYPHGDNGKQFSRMVTFGMTPIQALQAATINSAALLKQDNLGQIKPGFMADIIAVDGDPLKNISLMENVTFVMKDGQVYKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFF3</accession>
    <name>B1KFF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326458.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3870"/>
    <dbReference type="EnsemblBacteria" id="ACA88128">
        <property type="protein sequence ID" value="ACA88128"/>
        <property type="gene ID" value="Swoo_3870"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3870"/>
    <dbReference type="eggNOG" id="ENOG502ZZ0F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131508_1_0_6"/>
    <dbReference type="OMA" id="TGNFHWN"/>
    <dbReference type="OrthoDB" id="2011986at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021438">
        <property type="entry name" value="DUF3087"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11286">
        <property type="entry name" value="DUF3087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="20140" checksum="26BE1B15D04FA472" modified="2008-04-29" version="1" precursor="true">MKLIDIDKSRYRKNLNLVSIALVAGLTILSLVFGALLIAAFGTQASENIASGESTGNFHLNLLGVIFAVVVCLSVMIRVKDSAFMHEVYYVWRLKALHNRIYRRLKSIKAAANNHEVNALVILSFYYAGLKQVYFLDNNTLTMSKVEKDISELERRICESKQTVSLDQFDEKMLEAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV6</accession>
    <name>B1KFV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0979</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323619.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0979"/>
    <dbReference type="EnsemblBacteria" id="ACA85272">
        <property type="protein sequence ID" value="ACA85272"/>
        <property type="gene ID" value="Swoo_0979"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0979"/>
    <dbReference type="eggNOG" id="COG0347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082268_0_0_6"/>
    <dbReference type="OMA" id="CIRIRTE"/>
    <dbReference type="OrthoDB" id="2021322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="3">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12316" checksum="1077504FEB304E7A" modified="2008-04-29" version="1">MKLVSAIIKPFKLDDVREAIAGVGIEGMTVTEVKGFGRQKGHTELYRGAEYQVDFLPKVKLEIATKAENLELLIESIVNASRTGKIGDGKIFVSDLEQAIRIRTGELDNEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY2</accession>
    <name>B1KFY2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2411</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325031.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2411"/>
    <dbReference type="EnsemblBacteria" id="ACA86689">
        <property type="protein sequence ID" value="ACA86689"/>
        <property type="gene ID" value="Swoo_2411"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2411"/>
    <dbReference type="eggNOG" id="COG1448">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032440_1_2_6"/>
    <dbReference type="OMA" id="VGACTIV"/>
    <dbReference type="OrthoDB" id="417859at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="PTHR11879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="28"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="397" mass="43215" checksum="E7928CDC4F9BF5F5" modified="2008-04-29" version="1">MIFTQVELAPADPILGLTDAFKADKRTGKVNLGVGIYKNEAGLTPILASVKQAEAKLLASEESKSYLGIEGVQAYNDAVQSLLFGAGHQVVKDKRALTAQAPGGTGSLRVAAEFLARNTKSKTIWVSNPTWANHKNIFQSASLEIKEYRYYKAETHDKDFDAMVEDLSSAQAGDLVLLHGCCHNPTGIDLTQAQWKTIAQLCLKQELVPLFDFAYQGFGDGVDEDANGLRVVADTVPELIIANSFSKNFGLYNERIGAVTLVGDSQESVVKAFSQVKSTIRGNYSNPPAHGALIVSTILGDAELKALWERELKEMRERIAKMRTLFVETLKSEGVTQDFSFISRQNGMFSFSGLTKEQVAQLKDEHGVYIVGSGRISVAGMTKENMPVICKAIASVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG04</accession>
    <name>B1KG04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Appr-1-p processing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325053.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2433"/>
    <dbReference type="EnsemblBacteria" id="ACA86711">
        <property type="protein sequence ID" value="ACA86711"/>
        <property type="gene ID" value="Swoo_2433"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2433"/>
    <dbReference type="eggNOG" id="COG2110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046550_2_1_6"/>
    <dbReference type="OMA" id="KITRGYH"/>
    <dbReference type="OrthoDB" id="1812319at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="99"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="31924" checksum="88F5DB208795A3AA" modified="2008-04-29" version="1">MKLNDYADDIQLFSAFSKAERDVVDPLQQAINVIAADPMSASFVTRYPVPHAVKEKRGWLQAALTVRSPGQLPPELVLCVDSILQKEQVEKTVTDASTLERLTGGYPAASKISIWNGDITRLKIDAVTNAANAQMLGCFQPFHSCIDNAINCAAGPQLREDCNQLMQLQGSDETTGSAKITRAYNLPSKFVLHTVGPIIQHGAVPSPRQIDELASCYDACLSLAAEAGAQSVAVCGISTGVFGYPAEKAANVALQAVANWFLVNPDKLDHLVFNTFGDNATEIYHRAIGEWQHGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG70</accession>
    <name>B1KG70_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monovalent cation/proton antiporter, MnhG/PhaG subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326537.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3950"/>
    <dbReference type="EnsemblBacteria" id="ACA88207">
        <property type="protein sequence ID" value="ACA88207"/>
        <property type="gene ID" value="Swoo_3950"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3950"/>
    <dbReference type="eggNOG" id="COG1320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121334_2_3_6"/>
    <dbReference type="OMA" id="ATKCDTG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098662">
        <property type="term" value="P:inorganic cation transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005133">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34703">
        <property type="entry name" value="PTHR34703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03334">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01300">
        <property type="entry name" value="CPA3_mnhG_phaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="11999" checksum="B638B9D49FDAE094" modified="2008-04-29" version="1" precursor="true">MNLFLEISSGLCLLIGCFLCFSGGIGILRFPDFYTRMHAVSITDTLGAGLVLLGLMLQSPDGLVLIKLILILLFTLFINPSASHALAKAALHNGLSPQEDKGTNKGGDKPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG82</accession>
    <name>B1KG82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3962</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326549.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3962"/>
    <dbReference type="EnsemblBacteria" id="ACA88219">
        <property type="protein sequence ID" value="ACA88219"/>
        <property type="gene ID" value="Swoo_3962"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3962"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="VCMSKLR"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="118"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="118"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="221" mass="25091" checksum="0937648BBCE2E302" modified="2008-04-29" version="1">MTNKILIVEDDEKIATILAKYAQGSGYNHHIINDGAEVISWVKANEPDAILLDIMLPNVSGTELCKQIREFSEVPVLMATAKVEEIDRLLGLEIGADDYICKPFSPKEVMARIKTILRRVPTKAPDSLFQLDVVSQRAKLQNIELPLTPVEFRILHAFTSKPDNVWNREQLLNKMYDDYREVSDRTVDSHVANLRKKLLASQLKHDFIGSVYGVGYRFVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG83</accession>
    <name>B1KG83_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3963</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326550.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3963"/>
    <dbReference type="EnsemblBacteria" id="ACA88220">
        <property type="protein sequence ID" value="ACA88220"/>
        <property type="gene ID" value="Swoo_3963"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3963"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_6"/>
    <dbReference type="OMA" id="RTSWLIV"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="178"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="238"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="51381" checksum="A7E3F7A90A1D758A" modified="2008-04-29" version="1" precursor="true">MKLRNSVFIAIFATALISTIFLLLLQQIRFSYAFNEYMSKSRTERIEKLHLRLTDGFAETGNWQFLTDQFDTANSDNNTADEQNLERLNKWLLWFDFPRGVAILDANNAELIGEFESNMQLTAIFHQNEEVGFLAVKDNSEVKAELDSHFVKQQIRSLIFITLLTLLTALLSAYFFSRKLTRPISDIANVLNNLRKGDFSTRSEYKHSNELGQLSSDVNYLANTLEQNRDSRQRWITDISHELRTPITIMMGELECLEDGLTPFDSKAVTSLKEEVSGLNKLVADLHQLTIAEQGELRLECQPNNISEMVQKCLQKYQPIFTERDITTTNQLPSSLIAHVDKTRLQQVLVNLFENCARYTDIAGDIRISASQDNQFVTLVIENTAPEISEESLPKLFDRLYRVDESRNKFSGGSGLGLAICTAIVEAHGGKIRATYSSLNGLAVSMTLPVSSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG98</accession>
    <name>B1KG98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3978</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326565.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3978"/>
    <dbReference type="EnsemblBacteria" id="ACA88235">
        <property type="protein sequence ID" value="ACA88235"/>
        <property type="gene ID" value="Swoo_3978"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3978"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="MCAHVLV"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="234" mass="26385" checksum="0A7D639A4F7BED2F" modified="2008-04-29" version="1" precursor="true">MSAEKHILVVEDDISLAEWVSDYLLDHGYQVTVASQGDFALEMIAEEQPDLVLLDVMLPVKNGFDVCKEARAFYAGPILFMTACVEDGDEIQGLEVGADDYLTKPIRPKVMLARIKALLRRAIDDKLKQQLVFESLILNAAAKSVMVDDELLDLNANEFDVFWLLALQAGKVVSRIDLVSELRGIEYDGLDRSVDIRVSRLRKKLQEAKSQPYKIKTIRGKGYLFCRDDDEAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK5</accession>
    <name>B1KGK5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323679.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1040"/>
    <dbReference type="EnsemblBacteria" id="ACA85333">
        <property type="protein sequence ID" value="ACA85333"/>
        <property type="gene ID" value="Swoo_1040"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1040"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_15_6"/>
    <dbReference type="OMA" id="NLDGYDM"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="308"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="697"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="274"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="819" mass="92657" checksum="B48AC80A836F8E01" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK8</accession>
    <name>B1KGK8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1971 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323682.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1043"/>
    <dbReference type="EnsemblBacteria" id="ACA85336">
        <property type="protein sequence ID" value="ACA85336"/>
        <property type="gene ID" value="Swoo_1043"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1043"/>
    <dbReference type="eggNOG" id="COG3615">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147375_1_0_6"/>
    <dbReference type="OMA" id="ASIWKRH"/>
    <dbReference type="OrthoDB" id="1905128at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015392">
        <property type="entry name" value="DUF1971"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09313">
        <property type="entry name" value="DUF1971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1971" evidence="1">
        <location>
            <begin position="13"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="12126" checksum="CD8BE05E26FA608C" modified="2008-04-29" version="1">MSFTPKGYTHCESTQVYTCENVPKILLEPHYTKMGVYEQIHVLCGVLKYLGCNSHTQVTDKEVVIKANETAMAHPNYLHRLEPASDDLKFEIRFYSLEERSNTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGP2</accession>
    <name>B1KGP2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipopolysaccharide export system permease protein LptF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_1077</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the LptF/LptG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323716.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1077"/>
    <dbReference type="EnsemblBacteria" id="ACA85370">
        <property type="protein sequence ID" value="ACA85370"/>
        <property type="gene ID" value="Swoo_1077"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1077"/>
    <dbReference type="eggNOG" id="COG0795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028799_0_2_6"/>
    <dbReference type="OMA" id="ELQWRIA"/>
    <dbReference type="OrthoDB" id="1258802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030922">
        <property type="entry name" value="LptF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04407">
        <property type="entry name" value="LptF_YjgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="370" mass="41264" checksum="12D48F7EE4E4F498" modified="2008-04-29" version="1" precursor="true">MIVFRYLIREVLKAQIAVLFVLLAIFISQHFVRVLANASDGEFPASLVMTLLGLNLPYLAVLVLPLSFFLGILMAHGRMYAESEMVILHSVGVSEWYITRVTLLLAVINMLITGVLAVYVTPWAEERQNQVLEHAQSEAGLAAITQGRFQTSPNGRAVLFVERIGRDNELDKVFVAQLPDPEAEQGQSNIVLAQGGKVIEDETGGQRLQLRDGVQYQGTPKQVDFQVIEFGGYQMQIKEQEVNERRRKLSALPIEELMKQEGPESKAEFHWRLAIPLSIPLLTLIAVPMARVNVRQGKFAKMFPAILLYLGYFGLMIAGRKALEDGIIPGYLGMWWIHLSALILGGLLLGKERPSGVKITGLFKRKQVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT1</accession>
    <name>B1KGT1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325141.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2523"/>
    <dbReference type="EnsemblBacteria" id="ACA86800">
        <property type="protein sequence ID" value="ACA86800"/>
        <property type="gene ID" value="Swoo_2523"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2523"/>
    <dbReference type="eggNOG" id="COG3521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092347_4_0_6"/>
    <dbReference type="OMA" id="YIDHQDY"/>
    <dbReference type="OrthoDB" id="1864732at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017734">
        <property type="entry name" value="T6SS_SciN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038706">
        <property type="entry name" value="Type_VI_SciN-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37625">
        <property type="entry name" value="PTHR37625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12790">
        <property type="entry name" value="T6SS-SciN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03352">
        <property type="entry name" value="VI_chp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766590" evidence="1">
        <location>
            <begin position="19"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="176" mass="19902" checksum="9EC2B353B54539A8" modified="2008-04-29" version="1" precursor="true">MKTLRLAFLILLMGQLTACGSVWEGTKKVGAVIWDPSIPVGEPKDLPTQLTYSIVAQQDVNQNPNGDSTPIEFQLFELEDDSKLLAADYDSLTADFEDALGSNYIDHSDFTMLPGQFKFIEPFEVDEDTRYIGVMAHFGDPEVSQWKKVIKIKSIGREYHILILFKEQEVILDKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU0</accession>
    <name>B1KGU0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2532</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325150.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2532"/>
    <dbReference type="EnsemblBacteria" id="ACA86809">
        <property type="protein sequence ID" value="ACA86809"/>
        <property type="gene ID" value="Swoo_2532"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2532"/>
    <dbReference type="eggNOG" id="COG2194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018534_1_0_6"/>
    <dbReference type="OMA" id="NSIAFYF"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012549">
        <property type="entry name" value="EptA-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08019">
        <property type="entry name" value="EptA_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="EptA_B_N" evidence="9">
        <location>
            <begin position="56"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="8">
        <location>
            <begin position="234"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="544" mass="61662" checksum="FCD0FD9675E833D8" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGW8</accession>
    <name>B1KGW8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ion-translocating oxidoreductase complex subunit G</fullName>
            <ecNumber evidence="6">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Rnf electron transport complex subunit G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnfG</name>
        <name evidence="8" type="ordered locus">Swoo_2560</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RnfG family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325178.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2560"/>
    <dbReference type="EnsemblBacteria" id="ACA86837">
        <property type="protein sequence ID" value="ACA86837"/>
        <property type="gene ID" value="Swoo_2560"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2560"/>
    <dbReference type="eggNOG" id="COG4659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077882_1_0_6"/>
    <dbReference type="OMA" id="YSGAIHL"/>
    <dbReference type="OrthoDB" id="1381933at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00479">
        <property type="entry name" value="RsxG_RnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010209">
        <property type="entry name" value="Ion_transpt_RnfG/RsxG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36118">
        <property type="entry name" value="PTHR36118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006091">
        <property type="entry name" value="E_trnsport_RnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01947">
        <property type="entry name" value="rnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FMN_bind" evidence="7">
        <location>
            <begin position="97"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="6">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="23249" checksum="DAAFBDCB25A32076" modified="2008-04-29" version="1" precursor="true">MLRNGLILAIFAFFCTALVALVDRQTFDKIKEQQQLELKRVLHQIIPDTLHDNELIEHCILIHDEEVLGIDSPLPSYIASMKEVPVAIAMETVAPDGYSGNIRLIIGISTEGEVLGVRTLSHAETPGLGDKIELRKSDWVLGFNGMFLLSEDDARWNVKKDGGEIDQFTGATITPRAYVKAIKRALVYFNANKDRLLARPANCEVNYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX6</accession>
    <name>B1KGX6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325185.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2568"/>
    <dbReference type="EnsemblBacteria" id="ACA86845">
        <property type="protein sequence ID" value="ACA86845"/>
        <property type="gene ID" value="Swoo_2568"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2568"/>
    <dbReference type="eggNOG" id="COG3121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079620_0_0_6"/>
    <dbReference type="OMA" id="DGEYRSH"/>
    <dbReference type="OrthoDB" id="1105091at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="SSF49354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764864" evidence="1">
        <location>
            <begin position="21"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="29532" checksum="E1E69F8A25D67E62" modified="2008-04-29" version="1" precursor="true">MKKFFLSYFIASLFSSAAYANLLVTPTRVELDNKAQRSAVFSLVNKGKQDARYNIYFEDKKLLPTGDYVSLENSSTSLAKFVRYSPRRVSLAPEEGTRVRMALRLPKGTPEGEYRSYIVFHQIPLAPTAIDNEQKNTSNTLSLSVTAYMRISIPVILRLGALSSEVFIDADLDRKTQSSVEVTLVREGLRSSYGDIELFLVSSGQELENVGSYKNAAVYTELTARTFAIELSKPVERGRELIVRYRESESLSDAKVVETRIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH28</accession>
    <name>B1KH28_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase</fullName>
            <shortName evidence="10">NN:DBI PRT</shortName>
            <ecNumber evidence="4 10">2.4.2.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">N(1)-alpha-phosphoribosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobT</name>
        <name evidence="11" type="ordered locus">Swoo_4084</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate</text>
            <dbReference type="Rhea" id="RHEA:11196"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15890"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="EC" id="2.4.2.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CobT family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.21" evidence="4 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326669.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4084"/>
    <dbReference type="EnsemblBacteria" id="ACA88340">
        <property type="protein sequence ID" value="ACA88340"/>
        <property type="gene ID" value="Swoo_4084"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4084"/>
    <dbReference type="eggNOG" id="COG2038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002982_0_0_6"/>
    <dbReference type="OMA" id="AWMRKCA"/>
    <dbReference type="OrthoDB" id="1765140at2"/>
    <dbReference type="UniPathway" id="UPA00061">
        <property type="reaction ID" value="UER00516"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008939">
        <property type="term" value="F:nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02439">
        <property type="entry name" value="DMB-PRT_CobT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1610.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00230">
        <property type="entry name" value="CobT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003200">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017846">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023195">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036087">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02277">
        <property type="entry name" value="DBI_PRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52733">
        <property type="entry name" value="SSF52733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03160">
        <property type="entry name" value="cobT_DBIPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="7 10 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 11" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="346" mass="36782" checksum="8F35355BB3235AB0" modified="2008-04-29" version="1">MLGIGFDIAPISHEFDDEIQSRIDNKTKPLGALGELEFLAKQIARVLGKDKPKISNPKLLVFAADHGIAAAGVSIAPSEVTTQMVMNFINGGAAINVFCRQVGFELEVIDCGILQPLEGVEGIIDQRLGAGTAPIHRQAAMTLGAVKQGMEMARARIEHHHQLGCNLIALGEMGIGNTTSAAAIMACIMEMDSIDCVGRGTGIDAATLKRKQMLVEQALHVHESELADPFNILACLGGFEIVQMTGAMLAAAERGMLVVIDGFIATAAAMVAVKINPNVRGYMIFGHQSDERGHCLMMEHLHARPLLKLDMRLGEGTGAALALPMIQAAAGFYNEMASFSDAGIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH43</accession>
    <name>B1KH43_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326684.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4099"/>
    <dbReference type="EnsemblBacteria" id="ACA88355">
        <property type="protein sequence ID" value="ACA88355"/>
        <property type="gene ID" value="Swoo_4099"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4099"/>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1884375_0_0_6"/>
    <dbReference type="OMA" id="MYGTDWC"/>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="54"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="14355" checksum="AE8AE6FC9FC3FD43" modified="2008-04-29" version="1" precursor="true">MKSLIKTLLVYTFLFLMGTSAGYGVVLAYNKLSEPEVVLIGNYNHHFEGTDKKVIMYGTDWCPVCERAREFFNNEGISYKEVNPEKDESVFKLYSQLGASGYPIIVIGNKRVFGLDTKEIKVALTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH76</accession>
    <name>B1KH76_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323730.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1091"/>
    <dbReference type="EnsemblBacteria" id="ACA85384">
        <property type="protein sequence ID" value="ACA85384"/>
        <property type="gene ID" value="Swoo_1091"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1091"/>
    <dbReference type="HOGENOM" id="CLU_1739280_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="150" mass="17234" checksum="C30A43AC4652130B" modified="2008-04-29" version="1" precursor="true">MKTIQNIVILTFILFGQPSIADTMYCLVVSDVLINDDGKIVDPTIFDKSSIKSPENWIEFNLKSNTTSYFYSDDDGTKGNETENIIKINNQLFYAPVNDYTGYTTYLFEENMRNGILTEAAYVSTFNCVEKSQQEIEDIYGISFKPYYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHI3</accession>
    <name>B1KHI3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Phosphomethylpyrimidine kinase</fullName>
            <ecNumber evidence="16">2.5.1.3</ecNumber>
            <ecNumber evidence="16">2.7.4.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_2591</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP</text>
            <dbReference type="Rhea" id="RHEA:19893"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="16"/>
    <dbReference type="EC" id="2.7.4.7" evidence="16"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325208.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2591"/>
    <dbReference type="EnsemblBacteria" id="ACA86868">
        <property type="protein sequence ID" value="ACA86868"/>
        <property type="gene ID" value="Swoo_2591"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2591"/>
    <dbReference type="eggNOG" id="COG0351">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018272_7_1_6"/>
    <dbReference type="OMA" id="GHIFPTN"/>
    <dbReference type="OrthoDB" id="461201at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="16" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="9 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="15">
        <location>
            <begin position="22"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="TMP-TENI" evidence="14">
        <location>
            <begin position="343"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA86868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="535" mass="57065" checksum="8192DB7BC4CF70F5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR0</accession>
    <name>B1KHR0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Protein SprT</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sprT</name>
        <name evidence="5" type="ordered locus">Swoo_4132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SprT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4132"/>
    <dbReference type="EnsemblBacteria" id="ACA88388">
        <property type="protein sequence ID" value="ACA88388"/>
        <property type="gene ID" value="Swoo_4132"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4132"/>
    <dbReference type="eggNOG" id="COG3091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113336_0_1_6"/>
    <dbReference type="OMA" id="QHYPEPR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00746">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035240">
        <property type="entry name" value="SprT_Zn_ribbon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023483">
        <property type="entry name" value="Uncharacterised_SprT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17283">
        <property type="entry name" value="Zn_ribbon_SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SprT-like" evidence="4">
        <location>
            <begin position="62"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="212" mass="24622" checksum="1AEDE57374C66DE6" modified="2008-04-29" version="1">MLGFSEHRLIDEPVVLMFNLFRPSNTKTLSKKNLRAKSSTNQAEYFNLTHTFSSALHNQVALRVLECYDIAEKQLKQVFPRPEINFKLRGKSAGTAHLQQNQLRFNSTLLTENQDAFFEQVIPHEICHLLAHQLYGRVKPHGREWQALMVTLFKLHPSTTHSMNTQSVEGKQFSYRCDCGPVNLSVRRHNKVVRGETQYRCRRCKRELVADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ4</accession>
    <name>B1KHZ4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">23S rRNA (guanosine-2'-O-)-methyltransferase RlmB</fullName>
            <ecNumber evidence="6">2.1.1.185</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">23S rRNA (guanosine2251 2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">23S rRNA Gm2251 2'-O-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rlmB</name>
        <name evidence="8" type="ordered locus">Swoo_4216</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the ribose of guanosine 2251 in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2251) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10239"/>
            <dbReference type="Rhea" id="RHEA-COMP:10241"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="EC" id="2.1.1.185"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.185" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326800.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4216"/>
    <dbReference type="EnsemblBacteria" id="ACA88472">
        <property type="protein sequence ID" value="ACA88472"/>
        <property type="gene ID" value="Swoo_4216"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4216"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_0_1_6"/>
    <dbReference type="OMA" id="QVPPYEY"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070039">
        <property type="term" value="F:rRNA (guanosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01887">
        <property type="entry name" value="23SrRNA_methyltr_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024915">
        <property type="entry name" value="23S_rRNA_MeTrfase_RlmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="7">
        <location>
            <begin position="6"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="26213" checksum="C4CCA40E0987DDBA" modified="2008-04-29" version="1">MKKQDITFGIHAVEAVLKHSPERVIEMWVQAGRDDQRLASLLQMAAEYGISVQKAARKVLDDKSDSGQHQGVLARVKAVKQLNDNDLLSLVEKTETPFFLILDGVTDPHNLGACLRNADAAGVHGVIVPRDNSVGLTPTVSKVACGAAEVVPLFQVTNLARTMKSLQEKGVWIVGAAGEADSDLYKTDLKGPLAIAMGAEDKGLRRLTRESCDSIASIPMAGSVSSLNVSVATGICLFEAVRQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI15</accession>
    <name>B1KI15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323839.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85493">
        <property type="protein sequence ID" value="ACA85493"/>
        <property type="gene ID" value="Swoo_1200"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1200"/>
    <dbReference type="HOGENOM" id="CLU_1776172_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="146" mass="17305" checksum="F825C8E10F44CD4B" modified="2008-04-29" version="1">MFNPLKFLRWYKRYEVKILITILLVGLVYTIADSFLFKGKGKNEYFVEYFEKENLNFIHSSRSGNGFFLVFKHLNEREEVNSRELKAKFGQFIIHRVCHSPLLLKHMEQGGYVSVDVSAETTSYKVPRFNLNIRLDRCNDKITEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI33</accession>
    <name>B1KI33_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323857.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1218"/>
    <dbReference type="EnsemblBacteria" id="ACA85511">
        <property type="protein sequence ID" value="ACA85511"/>
        <property type="gene ID" value="Swoo_1218"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1218"/>
    <dbReference type="eggNOG" id="ENOG5030XW9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1432070_0_0_6"/>
    <dbReference type="OMA" id="GPELWCH"/>
    <dbReference type="OrthoDB" id="1674213at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767367" evidence="1">
        <location>
            <begin position="21"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20873" checksum="815F506ABCE115A0" modified="2008-04-29" version="1" precursor="true">MFKRLGLVITLICLSYSSFADSPLSGDKHVYLIDIKGKELMIGDIKFSNLAGKTHYQLHLDHSLFKDYFLSMKEMKCLEGPELWCHLAYPYSNPRTINQNDLSWLSHDLLFMYKKKSEFGANFYNGIYYQLSLNKGTIEGTAQAVDLNLLASAPDDLTLAPITEAELDEVEVAQRWLGRLIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI83</accession>
    <name>B1KI83_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1269</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323907.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1269"/>
    <dbReference type="EnsemblBacteria" id="ACA85561">
        <property type="protein sequence ID" value="ACA85561"/>
        <property type="gene ID" value="Swoo_1269"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1269"/>
    <dbReference type="eggNOG" id="COG1047">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098197_1_0_6"/>
    <dbReference type="OMA" id="HSHEGGC"/>
    <dbReference type="OrthoDB" id="2044224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="22428" checksum="882D892FAA67808F" modified="2008-04-29" version="1">MKITQHCAVSIHYRLSDEQGQVIEDSFEGEPMLYLHGAENMIPGLETELEGKVVGDKLDVTVNADNGYGPYHDGLRQEVPLSAFGDIQDIVPGMRFIAETEMGQRPVQVKEVKDDVVVVDGNHPLAGQSLNFIVEVMEVREATAEEIAHGHIHAHGSSCGSEHEHSHEGGCCGGGHEHNHEEGRCSDKKDEPAKEGCDGNGGCGCRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK8</accession>
    <name>B1KIK8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">OmpA/MotB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4248</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326831.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4248"/>
    <dbReference type="EnsemblBacteria" id="ACA88504">
        <property type="protein sequence ID" value="ACA88504"/>
        <property type="gene ID" value="Swoo_4248"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4248"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016890_6_2_6"/>
    <dbReference type="OMA" id="IGNYMDK"/>
    <dbReference type="OrthoDB" id="2018797at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039567">
        <property type="entry name" value="Gly-zipper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13488">
        <property type="entry name" value="Gly-zipper_Omp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767091" evidence="4">
        <location>
            <begin position="23"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="5">
        <location>
            <begin position="107"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="23538" checksum="AF7B69FDF6C9CB9E" modified="2008-04-29" version="1" precursor="true">MQSLKKFFAVKAVLACSLVALTGCQTTNPYTNESQNAKATNGAIIGAIAGAAIGVASSSKSDRGKGALIGAASGAALGGGIGYYMDTQEAELRKQLQSTGVSVTRSGDNIILNMPNEVTFGVDETHLSAGAKRVLNSVALVAKEYDKTRLNVLGFTDSSGSESYNLRLSKVRAVEVADYLVSQKVEYVRVKSDGMGEERPIASNATKEGRAENRRVEIILSPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP3</accession>
    <name>B1KIP3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zinc_ribbon_15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326866.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88539">
        <property type="protein sequence ID" value="ACA88539"/>
        <property type="gene ID" value="Swoo_4284"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4284"/>
    <dbReference type="eggNOG" id="ENOG5031H56">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2208271_0_0_6"/>
    <dbReference type="OrthoDB" id="1966455at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031493">
        <property type="entry name" value="Zinc_ribbon_15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17032">
        <property type="entry name" value="zinc_ribbon_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zinc_ribbon_15" evidence="1">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="107" mass="12310" checksum="800D963BC3948542" modified="2008-04-29" version="1">MFFLAGMDKKYEPIEPPISCHCSFCGVNREWVLYKETELASLFFITIWRFTPDYLLVCGSCQYPMKLPRELGKQLALDSSQITAKQDELASLVAEHQKVNITTNRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU9</accession>
    <name>B1KIU9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1305"/>
    <dbReference type="EnsemblBacteria" id="ACA85597">
        <property type="protein sequence ID" value="ACA85597"/>
        <property type="gene ID" value="Swoo_1305"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1305"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="WSFEGEA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767103" evidence="5">
        <location>
            <begin position="45"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="79"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="426"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="900" mass="98946" checksum="91292073E19331F4" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIX2</accession>
    <name>B1KIX2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4426 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323966.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1328"/>
    <dbReference type="EnsemblBacteria" id="ACA85620">
        <property type="protein sequence ID" value="ACA85620"/>
        <property type="gene ID" value="Swoo_1328"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1328"/>
    <dbReference type="eggNOG" id="ENOG503303T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141658_0_0_6"/>
    <dbReference type="OMA" id="PERKEVF"/>
    <dbReference type="OrthoDB" id="1793459at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025218">
        <property type="entry name" value="DUF4426"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14467">
        <property type="entry name" value="DUF4426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767105" description="DUF4426 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4426" evidence="2">
        <location>
            <begin position="24"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="144" mass="16090" checksum="CE2095DCB191F660" modified="2008-04-29" version="1" precursor="true">MLKAILSALILSLALVGNVSAEQKQKIGNFDIHYVALSSTFLTPSIAKSYGIKRSSYTGIINISVLDTSQEGNPAVPVQISGVANNLLDARITLKFREIREGEAIYYIAEVPYRDDQEINFNIAIQYAKKLNTQLKFKQKFYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ85</accession>
    <name>B1KJ85_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 16">NAD(P) transhydrogenase subunit beta</fullName>
            <ecNumber evidence="7 16">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Nicotinamide nucleotide transhydrogenase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">Swoo_2830</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the PNT beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="7 16"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325441.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2830"/>
    <dbReference type="EnsemblBacteria" id="ACA87105">
        <property type="protein sequence ID" value="ACA87105"/>
        <property type="gene ID" value="Swoo_2830"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2830"/>
    <dbReference type="eggNOG" id="COG1282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007866_4_0_6"/>
    <dbReference type="OMA" id="KRGMSAG"/>
    <dbReference type="OrthoDB" id="788546at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012136">
        <property type="entry name" value="NADH_DH_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000204">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9 16" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15 16 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0520">NAD</keyword>
    <keyword evidence="12 16" id="KW-0521">NADP</keyword>
    <keyword evidence="19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16" id="KW-1278">Translocase</keyword>
    <keyword evidence="11 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB" evidence="18">
        <location>
            <begin position="7"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00014581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACA87105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="466" mass="48909" checksum="640C49E5A0032BA2" modified="2008-04-29" version="1" precursor="true">MSIGLLSAAYLVAAVLFIFSLAGLSKQETAQRGNILGIIGMVIAVIATLASTQIEGNSWIVTGAMAIGAAIGVRLALKVEMTEMPELVAILHSFVGMAAVLVGFSSTLDHGSLMDAVTGQIDPVAKTIHDVEVFLGIFIGAVTFTGSVVAFAKLRGLVKSAPKSLPGAHWLNLGMIVVSVILGIYYMQTDAITALVIMTFIAFVFGYNLVSAIGGADMPVVVSMLNSYSGWAAAAAGFMLGNDLLIITGALVGSSGAILSYIMCKAMNRSFISVILGGFGSEGGTMAAGDAEQGEHREVQADDVAEMLKNARNVIIAPGYGMAVAQAQYPVAEITQKLRQRGVNVRFAIHPVAGRLPGHMNVLLAEAKLPYDIVMEMDEINEDFADTDVVLVIGANDTVNPAAKEPGSPISGMPVLEVWNAENVVVFKRSMATGYAGVQNPLFFKENTEMLFGDAKESVSKILASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJK1</accession>
    <name>B1KJK1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Riboflavin biosynthesis protein RibD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="10">DRAP deaminase</shortName>
                <ecNumber evidence="10">3.5.4.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Riboflavin-specific deaminase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
                <ecNumber evidence="10">1.1.1.193</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">HTP reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_1382</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="10"/>
    <dbReference type="EC" id="1.1.1.193" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324020.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1382"/>
    <dbReference type="EnsemblBacteria" id="ACA85674">
        <property type="protein sequence ID" value="ACA85674"/>
        <property type="gene ID" value="Swoo_1382"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1382"/>
    <dbReference type="eggNOG" id="COG0117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_1_2_6"/>
    <dbReference type="OMA" id="DEMYMAR"/>
    <dbReference type="OrthoDB" id="1775351at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006769">
        <property type="entry name" value="RibD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 12" id="KW-0521">NADP</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="8 10 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="5"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="312"/>
            <end position="318"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA85674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="379" mass="40986" checksum="554BF95CEDA2243D" modified="2008-04-29" version="1">MNWSVEDIEMMSRAIKLARQGLYTTQPNPCVGCVVTKDGQILGEGFHIKAGGPHAEVHALAMANSDSNLGAKGATAYVTLEPCSHYGRTPPCAEALIHNKLARVVVAVEDPNPQVCGRGIAMLRDAGIQVDVGLLQDEAYKINPGFMKRMETGLPWVTVKLASSLDGKTALANGASKWITGPEARRDVQRLRARHCALVTGVETILADNPSLNVRHSELGSLADRHSESDLHQPLRVVLDSRARVTSDLALFAIESPILLVSCDDYPAIEQQSWPSHVKQVKLNCDESGRVDLNELFKYLGKQCNSVLIEAGATLAGSVIAKGHGDELVLYQALKMLGSSGRNLITLPEYTAMSQIPAIKLVDERKVGADTRLTLDIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM0</accession>
    <name>B1KJM0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85693">
        <property type="protein sequence ID" value="ACA85693"/>
        <property type="gene ID" value="Swoo_1401"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1401"/>
    <dbReference type="eggNOG" id="ENOG5032V1H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088845_0_0_6"/>
    <dbReference type="OMA" id="QMNINVS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="283" mass="32036" checksum="B57BC11D4A687252" modified="2008-04-29" version="1">MINRALNSLENMSTVIEIDFSKRLEIKIDNKQPVGLEDLSLSLLSFNKQFHKFVESETDALTDIGSELLIKEVRKGSIIVELVSQSAPIVPLLWDGGSLAQWASVVQNTCNWLLGKSDNSPKNLTKQDLQEWNKIVEPIAKDNGSQMNINVSDGGKVINQFILSSNEAAAIQNRIGRLVEDIDTPVENRHLKKVMYWYQTKFDRNSDTGNKAIIDDISKSALKVIFENNALKEEMLHPDPSLGKPWQELAFIVDVEVQTVRGKPKMYNVLNYYPEYTFDPDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ0</accession>
    <name>B1KJQ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1431</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324069.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1431"/>
    <dbReference type="EnsemblBacteria" id="ACA85723">
        <property type="protein sequence ID" value="ACA85723"/>
        <property type="gene ID" value="Swoo_1431"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1431"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="GRMPRWR"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="25045" checksum="A8D47B779C05F0BB" modified="2008-04-29" version="1" precursor="true">MSIEISQLSKTYNPESDFPVHAVQSLDLTIEQGEFVAVMGPSGSGKTTLLNMIGGIDTPTSGCVLIDSENICELDDKALIAFRRDHVGFIFQDYSLLPVLTALENVEFVMQLQGLSEKECRARASELLTMVGLGEQMHKVPSKLSGGQQQRVAVARALAPRPRFVMADEPTANLDAKSTSELLDIMQSLNEKEGTTFIFSTHDQRVIKRAKRVIVFEDGKLTEDKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJS0</accession>
    <name>B1KJS0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324089.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1454"/>
    <dbReference type="EnsemblBacteria" id="ACA85743">
        <property type="protein sequence ID" value="ACA85743"/>
        <property type="gene ID" value="Swoo_1454"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1454"/>
    <dbReference type="eggNOG" id="ENOG5033FEU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178564_0_0_6"/>
    <dbReference type="OMA" id="AAGIFCP"/>
    <dbReference type="OrthoDB" id="2036964at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="79" mass="9125" checksum="17534258906DA273" modified="2008-04-29" version="1">MTTETNKIDFSIINKTTAKSFNEQKNLIKRLFKGNTVQCETCKQPLTLIVPTEKDTEKKYGVFCKKHCTDIELELELVL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK02</accession>
    <name>TRPB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="1">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trpB</name>
        <name type="ordered locus">Swoo_2916</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325525.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KK02"/>
    <dbReference type="SMR" id="B1KK02"/>
    <dbReference type="STRING" id="392500.Swoo_2916"/>
    <dbReference type="EnsemblBacteria" id="ACA87189">
        <property type="protein sequence ID" value="ACA87189"/>
        <property type="gene ID" value="Swoo_2916"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2916"/>
    <dbReference type="eggNOG" id="COG0133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016734_3_1_6"/>
    <dbReference type="OMA" id="HGMKSYF"/>
    <dbReference type="OrthoDB" id="912282at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="chain" id="PRO_1000095823" description="Tryptophan synthase beta chain">
        <location>
            <begin position="1"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <sequence length="407" mass="44012" checksum="A6545707063073E8" modified="2008-04-29" version="1">MTKLDPYFGEYGGMYVPQILMPALKQLETAFVEAQEDEAFKTEFNDLLKNYAGRPTALTLTRNLSPNPLVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLDLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSSTLKDACNEAMRDWSGSYDKAHYLLGTAAGPHPFPTIVREFQRMIGAETKKQILEREGRLPDAVIACVGGGSNAIGMFADFIDEESVKLIGVEPAGLGIDTPMHGAPLKHGKTGIFFGMKAPLMQDREGQIEESYSISAGLDFPSVGPQHAHLAATGRATYESATDDEALEAFQLLARSEGIIPALESAHALAYAVKMAKAATQETILVVNLSGRGDKDIFTVADILEERERSQTGQQKEESGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK86</accession>
    <name>B1KK86_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327043.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88717">
        <property type="protein sequence ID" value="ACA88717"/>
        <property type="gene ID" value="Swoo_4466"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4466"/>
    <dbReference type="eggNOG" id="ENOG502ZUNR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1233626_0_0_6"/>
    <dbReference type="OMA" id="FYNEWIE"/>
    <dbReference type="OrthoDB" id="2067726at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="22258" checksum="2AED9FE4B4BB6188" modified="2008-04-29" version="1">MALHPHVHDFYNEWIEKADNYNGQQLSDYFNKAFSLFTLYNKLYAEATFELARREEVVLNNHFPDRRGATEYAPQFIGYESLYQIITTEQGCRVCLQNLIERISNHEFYIKLSMPYGERQIEEDNELVTRLNSTDHVVKVGAVLDLIYSVRCNMFHGNKQFAQVQVDLLAPLTVILRRIIVALYAALQSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK96</accession>
    <name>B1KK96_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4476</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327053.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4476"/>
    <dbReference type="EnsemblBacteria" id="ACA88727">
        <property type="protein sequence ID" value="ACA88727"/>
        <property type="gene ID" value="Swoo_4476"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4476"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136831_0_0_6"/>
    <dbReference type="OMA" id="HMADGIF"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764987" evidence="1">
        <location>
            <begin position="24"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="52"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15928" checksum="C2F17DC77DB5FAC8" modified="2008-04-29" version="1" precursor="true">MNRVLGSVVFTILLSMLSAVSYAGGGQEMGPAKYYDEPLNTITMMEAQTLVGKEGVYFFDVNTLELWAEGFIPGAVYFNVKNWKDLLPKNKDAQMIFYCANRLCNASEIAARHVMKLGYTGVRQMPDGIYGWRLANRVTEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC8</accession>
    <name>B1KKC8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324114.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1480"/>
    <dbReference type="EnsemblBacteria" id="ACA85768">
        <property type="protein sequence ID" value="ACA85768"/>
        <property type="gene ID" value="Swoo_1480"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1480"/>
    <dbReference type="eggNOG" id="ENOG502ZAGB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_323878_0_0_6"/>
    <dbReference type="OMA" id="VENINPY"/>
    <dbReference type="OrthoDB" id="1406185at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="892" mass="96520" checksum="5B6A9CC03CE663E1" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKE5</accession>
    <name>B1KKE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324131.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1497"/>
    <dbReference type="EnsemblBacteria" id="ACA85785">
        <property type="protein sequence ID" value="ACA85785"/>
        <property type="gene ID" value="Swoo_1497"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1497"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_4_0_6"/>
    <dbReference type="OMA" id="IVGCKWS"/>
    <dbReference type="OrthoDB" id="2057904at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="117" mass="13302" checksum="DF6A83DE4E4EB11C" modified="2008-04-29" version="1">MTLKEKEISDLQQRVVGPSESARMVETIVGCKWSLTVYQLLAQEINRPGEMVRCVDGLTTKVLNQCLKRNVEFGILEKLSYPEIPPRVEYRVTPFGSKFMTILDALKDLQEEIQKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKS9</accession>
    <name>B1KKS9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325632.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3025"/>
    <dbReference type="EnsemblBacteria" id="ACA87296">
        <property type="protein sequence ID" value="ACA87296"/>
        <property type="gene ID" value="Swoo_3025"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3025"/>
    <dbReference type="eggNOG" id="ENOG5033GPN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_195345_0_0_6"/>
    <dbReference type="OMA" id="ISAWYFG"/>
    <dbReference type="OrthoDB" id="2059525at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="68" mass="7336" checksum="49DE6D5A8E03E4CC" modified="2008-04-29" version="1" precursor="true">MLLSIFIVTVLPLSGYVMGKLAFQAGLGVKRWAVVGLLLGPAGYPLLNTYKRFAMKKASVKGSSQFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKT9</accession>
    <name>B1KKT9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327071.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4494"/>
    <dbReference type="EnsemblBacteria" id="ACA88745">
        <property type="protein sequence ID" value="ACA88745"/>
        <property type="gene ID" value="Swoo_4494"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4494"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056292_2_0_6"/>
    <dbReference type="OMA" id="VAPNLMH"/>
    <dbReference type="OrthoDB" id="313524at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="PTHR33835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="26110" checksum="6194C65C890C72DB" modified="2008-04-29" version="1">MSLVQLGENIWAHEDSMPLGGIQLRLRMTIVKLSCGGLWIHSPTKPNPELQAEIDELGKVTFIVGAANGHNTWLSAWQTAYPEAELYVSGGIPNKVKLDNYMVLEKHFENIWCDDFEREFMPNVELFNESVFFHKPSRSLIVTDLIQNHSDEIPSGFAGVMTRCVFRPLGFKGACVAPPLKLGFTIKDKSAFSVFIKNIQRWDFDKIIVTHGDVIADDAKGVFAGLVERFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV5</accession>
    <name>B1KKV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327087.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88761">
        <property type="protein sequence ID" value="ACA88761"/>
        <property type="gene ID" value="Swoo_4510"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4510"/>
    <dbReference type="eggNOG" id="COG2841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165482_2_0_6"/>
    <dbReference type="OMA" id="MFHEYRD"/>
    <dbReference type="OrthoDB" id="2093541at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007420">
        <property type="entry name" value="DUF465"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038444">
        <property type="entry name" value="DUF465_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04325">
        <property type="entry name" value="DUF465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="73" mass="8654" checksum="0162098E60581FD3" modified="2008-04-29" version="1">MFPEYRDLITKLKTDDAHFLKVFNKHNALDDEIKELEQHSSTVFTNEVQELKKKKLHIKEELHAILKSVKPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL32</accession>
    <name>B1KL32_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0072</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322722.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0072"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84373">
        <property type="protein sequence ID" value="ACA84373"/>
        <property type="gene ID" value="Swoo_0072"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0072"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_24_0_6"/>
    <dbReference type="OMA" id="GCNMAFW"/>
    <dbReference type="OrthoDB" id="1445278at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_7C" evidence="3">
        <location>
            <begin position="168"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="282" mass="32097" checksum="0374828853AF3905" modified="2008-04-29" version="1">MTSSLIITTYNWPEALARVLESVMSQSVTPDEIIIADDGSTEETKEVIRQYQGRSSIPIIHSWQEDNGFRLSRSRNKAISVAKMDYIIMIDGDMILHHKFIADHLKHAEKGFFITGKRVKLSAELSQKQFKSPKPLTLFSRGLSRGRENAFRLAWQPKLMSKTQTTSVEGIHGCNLAFWKADVLTVNGFNTQFEGWGPEDKEFALRMINSGIKRKRLKYAGIAFHIYHDESPKTLLEANRAIFEDIQINRARWCPLGINEFIAVELPQVDEFDASLVTHSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL33</accession>
    <name>B1KL33_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322723.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0073"/>
    <dbReference type="EnsemblBacteria" id="ACA84374">
        <property type="protein sequence ID" value="ACA84374"/>
        <property type="gene ID" value="Swoo_0073"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0073"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076613_0_0_6"/>
    <dbReference type="OMA" id="VIAGVPC"/>
    <dbReference type="OrthoDB" id="1562620at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="29408" checksum="F140948B3AF01E1B" modified="2008-04-29" version="1">MDHPNVSFVLTSCNRFDLLEETLISFFKFNTYPIAQYVIIEDSHNRDKLDRVLAKFPDIDFTVLNNEPQLGQMKSIDRAYSVVTSEYIFHCEDDWEFYREGFIEESFKVLNADEKVVTIWLREQDDTNEHPVEPEIFYCGEDNSTPYQIMMRNHRRREHSSLWHGFTFNPGLRRLKDYQLFAPIGELGGELNMSELYHEKGFKAAIFPKGSVRHIGDHRGIRYKVGQSQLAKDFSVGFKRVKAKVCHILGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL80</accession>
    <name>B1KL80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322770.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0120"/>
    <dbReference type="EnsemblBacteria" id="ACA84421">
        <property type="protein sequence ID" value="ACA84421"/>
        <property type="gene ID" value="Swoo_0120"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0120"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_3_6"/>
    <dbReference type="OMA" id="RFQAMQV"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="32901" checksum="73A695DE4D7F9638" modified="2008-04-29" version="1">MNIEDLRLFVRLAVTNNISKAGQDLGLSPPLASIHINRLEKTLGARLVHRTTRKVSLTEEGITFLPHAEEIILRVDEAMESVGKGLTRPQGVLKISAPSSFGRMHLMPALKGFLTQHPAISVDIQLTDTMVDLVAGGFDVGIRNSELKSSSLVARKLAVDRRIICASPEYIRENGQPSSPEELRDHQCINLKGLEGWTFETLNGNVNINTKGNVRVDQGEAVRDACINGMGVAMCATWIAYEHLKRGDLIQILKDYPLIDDASIWAIYPSSKLLAPKIRAFIDYFSVYYGTPAYWDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL88</accession>
    <name>B1KL88_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322778.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0128"/>
    <dbReference type="EnsemblBacteria" id="ACA84429">
        <property type="protein sequence ID" value="ACA84429"/>
        <property type="gene ID" value="Swoo_0128"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0128"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_3_6"/>
    <dbReference type="OMA" id="RPMVSRY"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="302" mass="34452" checksum="93500C541D7C39DE" modified="2008-04-29" version="1">MDSAQLYRMLVFANVVEQGSLTGAADELGISRSMVSQHLKKLELRCETQLIERTTRKMALTEDGQQLYHHCAELLLLAKQAEETTQPKSTELRGRVSLLTPICFGEQFITPHIGEFRRQFPKLEINLQLDDRRINRLENSVDIAIQNETQQPTDTSFIKLGQFDEYIVATPEYVQQHGSPLHPDMLLNHQWILQTSTHLPQSFLLENSYGDKFTIKVSPFICCNSRHGISQMVKQGAGIAILPSYLVEDEIAQGELIHILPDYHLDEGGVYAIHPFDKVIPPRVKAFLDFIQIKMKPENMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD2</accession>
    <name>B1KLD2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324203.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1571"/>
    <dbReference type="EnsemblBacteria" id="ACA85857">
        <property type="protein sequence ID" value="ACA85857"/>
        <property type="gene ID" value="Swoo_1571"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1571"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_6"/>
    <dbReference type="OMA" id="AAEHFFC"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="23170" checksum="0C76109C1F813862" modified="2008-04-29" version="1">MTSTPTANLSRSEQKRVQILEAAIDLFCGQGFPNTSMDEVAKKAGVSKQTVYSHFGCKDDLFVASIESKCVVHNLTEELFADPHHPEKALASFGEYFSEMIVSPEALKVFTACVAQAETHPEISELFYNAGPEHLLNLMSDYLTLVEQAGVYQFGNTRSCSVRLCLMMFGEMRMKLELGLGVEELIEGREAYIQECVDMFLRAYKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD4</accession>
    <name>B1KLD4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chalcone_isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324205.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1573"/>
    <dbReference type="EnsemblBacteria" id="ACA85859">
        <property type="protein sequence ID" value="ACA85859"/>
        <property type="gene ID" value="Swoo_1573"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1573"/>
    <dbReference type="eggNOG" id="ENOG502ZD7C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102167_0_0_6"/>
    <dbReference type="OMA" id="IWLGEKP"/>
    <dbReference type="OrthoDB" id="1954032at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16036">
        <property type="entry name" value="Chalcone_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="SSF54626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767178" description="Chalcone_isomerase domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone_isomerase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="20198" checksum="A068E382C858622B" modified="2008-04-29" version="1" precursor="true">MSLTHSITKLSLIGSLLFASSTSAMEISGVQLPEQITLAHTELQLNGAGVRSKFFIDLYVGSLYLTAANSDPAQIIDADQSAIRLNITSGMITADKMRDAITEGFDDATEGKTAAIQSQIDAFMALFSEEIKEGDQFTLATSKASGVTAYKNNIAQATIEGEAFRQALLKIWLGDEPAQSSLKKAMLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK1</accession>
    <name>B1KLK1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324272.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1640"/>
    <dbReference type="EnsemblBacteria" id="ACA85926">
        <property type="protein sequence ID" value="ACA85926"/>
        <property type="gene ID" value="Swoo_1640"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1640"/>
    <dbReference type="eggNOG" id="ENOG5031EE3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105420_0_0_6"/>
    <dbReference type="OMA" id="QILLMVP"/>
    <dbReference type="OrthoDB" id="1892631at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22712" checksum="788417BF656EA55E" modified="2008-04-29" version="1" precursor="true">MAKSKGKFSTFSILIIFLLSVAVFVFASLYLEIRHKNELLVSEVQRLESSQVLLMVPDEQAEVVAKWMSENPEATKALLEQAKPKQEVKVSVGPGVVDSVVDTPVFDKNSTTAALEVSDKHVDETQPVSEVLPQAKRTENTIDDMIEVLPNEAVVPFQEAIEDTISTDEGDESRLIAPRTISEDEQGVKVIVLPHGGIRVTTREND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLM1</accession>
    <name>B1KLM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325654.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3047"/>
    <dbReference type="EnsemblBacteria" id="ACA87318">
        <property type="protein sequence ID" value="ACA87318"/>
        <property type="gene ID" value="Swoo_3047"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3047"/>
    <dbReference type="eggNOG" id="ENOG5031D5W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141025_0_0_6"/>
    <dbReference type="OMA" id="GFAPKEF"/>
    <dbReference type="OrthoDB" id="1884032at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021230">
        <property type="entry name" value="DUF2810"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10928">
        <property type="entry name" value="DUF2810"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="13166" checksum="0970FF99143B32F2" modified="2008-04-29" version="1">MNLKEELHGLSDKLEQFRRKLAAAEKRGDKGVMLQFRQEINAVTKRIASVKAQQTRELSKQGGSVVSMKFNRPLTKAEQADMGKLKKSVRGLVVVHPMTALGREMGIKVVTGFAPKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM27</accession>
    <name>B1KM27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c-type biogenesis protein CcmI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4657</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327231.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4657"/>
    <dbReference type="EnsemblBacteria" id="ACA88907">
        <property type="protein sequence ID" value="ACA88907"/>
        <property type="gene ID" value="Swoo_4657"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4657"/>
    <dbReference type="eggNOG" id="COG4235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036074_2_1_6"/>
    <dbReference type="OMA" id="IMQQMIG"/>
    <dbReference type="OrthoDB" id="1539126at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017560">
        <property type="entry name" value="Cyt_c_biogenesis_CcmI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03142">
        <property type="entry name" value="cytochro_ccmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="416" mass="45675" checksum="BEB3CC1862904AA9" modified="2008-04-29" version="1" precursor="true">MTTLWIFIALFLLVSLVLIWFPHFRQQKMLQTEEAGVRKQTNLELFNNRLATLEKELEDEQLDQVEFDALKKELEISLLQDMKQGSSDESLVTKMKPKGLLWPVVMSVAVLGISGYFYTSLGAYANLDKTEQASPHAGMTADQVMQQRLQMMEAQAKAEPENSQLLFSLGHSYISANRYDDAIKTFDKAMVLVGTHAELLGPKATAMYYKANQQMTPAVQAIVDQALSLDPEDPSTLLLVGMDSFFTANYQKAIDSWQIILDSDRKDVDRSAIINAIDSAKMRMQADTGEMPNDAAHANVQNTAKTVNVEVSVSDELAQQVGSSDMLFIFARNTEGPKVPLAAVKVSAKSLPTTITLDDTTSMGGDVKLSGAKQVEIIAVLSKHGTVKPQSGDLKGHLAMVNVGDTAQLIIDTQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM81</accession>
    <name>B1KM81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0319 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322843.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0193"/>
    <dbReference type="EnsemblBacteria" id="ACA84494">
        <property type="protein sequence ID" value="ACA84494"/>
        <property type="gene ID" value="Swoo_0193"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0193"/>
    <dbReference type="eggNOG" id="COG3110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133824_0_0_6"/>
    <dbReference type="OMA" id="NDGMGSE"/>
    <dbReference type="OrthoDB" id="1947544at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018635">
        <property type="entry name" value="UPF0319"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09829">
        <property type="entry name" value="DUF2057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764658" evidence="2">
        <location>
            <begin position="20"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="15598" checksum="C805628B942BD48F" modified="2008-04-29" version="1" precursor="true">MKTLITAVALTFASFTSLAASVSFPESIDVTGVNGKSQLNNHQIELTKGENLIELKYYDIFEANADDSGAWVKSQPLYLLISAETQDQYNALTPRIDTEEEAYDFINNPVLTLKNTTGKEKEVTLLTHHQLMAKLLFAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB1</accession>
    <name>B1KMB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322873.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0223"/>
    <dbReference type="EnsemblBacteria" id="ACA84524">
        <property type="protein sequence ID" value="ACA84524"/>
        <property type="gene ID" value="Swoo_0223"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0223"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_11_0_6"/>
    <dbReference type="OMA" id="PHETTHG"/>
    <dbReference type="OrthoDB" id="1814691at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="62"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17135" checksum="0FE46A8FE693B631" modified="2008-04-29" version="1">MQTDDCWCSGEIADQRARKIGIEMLENDQGSQRLGLKITKHNARQCQVEMSVTSNMTNGHDICHGGYIFSLADSALAFACNGVGVVAVTSAAQIDFMNAANLGDVLSAEATVKFRQGRQLICDVKICNQESQLIALCRGRQVSLNNRAQTQNTIGNNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB8</accession>
    <name>B1KMB8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322880.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0230"/>
    <dbReference type="EnsemblBacteria" id="ACA84531">
        <property type="protein sequence ID" value="ACA84531"/>
        <property type="gene ID" value="Swoo_0230"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0230"/>
    <dbReference type="eggNOG" id="COG4774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_15_2_6"/>
    <dbReference type="OMA" id="DAYYTSV"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766834" evidence="6">
        <location>
            <begin position="23"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="51"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="296"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="729" mass="80552" checksum="CB3683902F0BBA03" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC0</accession>
    <name>B1KMC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322882.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0232"/>
    <dbReference type="EnsemblBacteria" id="ACA84533">
        <property type="protein sequence ID" value="ACA84533"/>
        <property type="gene ID" value="Swoo_0232"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0232"/>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024976_0_0_6"/>
    <dbReference type="OMA" id="YKQVERS"/>
    <dbReference type="OrthoDB" id="95112at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020016">
        <property type="entry name" value="Decahaem-assoc_OM_MtrB/PioB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11854">
        <property type="entry name" value="MtrB_PioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03509">
        <property type="entry name" value="OMP_MtrB_PioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765053" evidence="1">
        <location>
            <begin position="22"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="668" mass="74179" checksum="0AE33E00B782CF3A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMK4</accession>
    <name>B1KMK4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HTH-type transcriptional regulatory protein TyrR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1717</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324348.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1717"/>
    <dbReference type="EnsemblBacteria" id="ACA86002">
        <property type="protein sequence ID" value="ACA86002"/>
        <property type="gene ID" value="Swoo_1717"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1717"/>
    <dbReference type="eggNOG" id="COG3283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_8_2_6"/>
    <dbReference type="OMA" id="CQNRIGI"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030828">
        <property type="entry name" value="HTH_TypR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18024">
        <property type="entry name" value="HTH_50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04381">
        <property type="entry name" value="HTH_TypR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="78"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="8">
        <location>
            <begin position="205"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="512" mass="58051" checksum="242A557FB7415BD7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMM9</accession>
    <name>B1KMM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325743.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3136"/>
    <dbReference type="EnsemblBacteria" id="ACA87407">
        <property type="protein sequence ID" value="ACA87407"/>
        <property type="gene ID" value="Swoo_3136"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3136"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128690_0_0_6"/>
    <dbReference type="OMA" id="NLPPYFH"/>
    <dbReference type="OrthoDB" id="1497607at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="200" mass="22331" checksum="EC781984609FB170" modified="2008-04-29" version="1">MNEFEDLCHFRTPRLTVSSWWEHVNCGVSEVKLAQTVLETLTPGVTATLPEGWQDINHIEDALLWMNDRASESCFLVVQESSDDQVIGFVFLHELAQELEAIAQGADNASIKSELHLGYLLAENYWGKGYASELIAGLVEWAKASGEVKSFVGGVDIDNTASIMVMEKNGFTFHQSEGRNNTLFMQLELDKPSLSRSKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV5</accession>
    <name>B1KMV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325819.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87483">
        <property type="protein sequence ID" value="ACA87483"/>
        <property type="gene ID" value="Swoo_3213"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3213"/>
    <dbReference type="eggNOG" id="ENOG502ZGC8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_188515_1_0_6"/>
    <dbReference type="OMA" id="RFVILPW"/>
    <dbReference type="OrthoDB" id="1952282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022072">
        <property type="entry name" value="DUF3624"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12292">
        <property type="entry name" value="DUF3624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9760" checksum="C2761DD5A377D549" modified="2008-04-29" version="1">MTCKNCNSSLFQQKIGRCKSCMWQLTLLSLISWPLWWYFYADAPKQINSIALLFFCTAFTGLLSLHLLVLGYRTLIDWFNSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN21</accession>
    <name>B1KN21_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system protein J</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4728</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP J family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327295.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4728"/>
    <dbReference type="EnsemblBacteria" id="ACA88978">
        <property type="protein sequence ID" value="ACA88978"/>
        <property type="gene ID" value="Swoo_4728"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4728"/>
    <dbReference type="eggNOG" id="COG4795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093850_0_0_6"/>
    <dbReference type="OMA" id="WYYPYPE"/>
    <dbReference type="OrthoDB" id="1213602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010055">
        <property type="entry name" value="T2SS_protein-GspJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11612">
        <property type="entry name" value="T2SSJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01711">
        <property type="entry name" value="gspJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="205"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="211"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="264" mass="28193" checksum="DB01510E71DF386C" modified="2008-04-29" version="1" precursor="true">MCSTKINKTAGFTLLEMIIAIAIFSMLGLASNAVLQNVMRNDEVTKDFSNRLKAMQQGFGALERDFGQMVARSPRLLEGGRGTTVFQTGSDILDSESEALVFFRIGWLNPDGILPRGSIQSVVYVVSENNLERWYYPYPEPEFGSDPIKTIVMRDVISVEYSFFVEDKWERKVDAANLPKAIAMEIELEGVGKIQRKFLLPVGAKAGSGDDNGSNGGNNNGDNKDGSNNTGGGSSSGGSSGGGSNNGGGTNNGEDENGREKGGG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN33</accession>
    <name>PCKA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="1">PCK</shortName>
            <shortName evidence="1">PEP carboxykinase</shortName>
            <shortName evidence="1">PEPCK</shortName>
            <ecNumber evidence="1">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pckA</name>
        <name type="ordered locus">Swoo_4740</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327307.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KN33"/>
    <dbReference type="SMR" id="B1KN33"/>
    <dbReference type="STRING" id="392500.Swoo_4740"/>
    <dbReference type="EnsemblBacteria" id="ACA88990">
        <property type="protein sequence ID" value="ACA88990"/>
        <property type="gene ID" value="Swoo_4740"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4740"/>
    <dbReference type="eggNOG" id="COG1866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018247_0_1_6"/>
    <dbReference type="OMA" id="MRYAGEM"/>
    <dbReference type="OrthoDB" id="146648at2"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0210">Decarboxylase</keyword>
    <keyword id="KW-0312">Gluconeogenesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000192334" description="Phosphoenolpyruvate carboxykinase (ATP)">
        <location>
            <begin position="1"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="220"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <sequence length="513" mass="56084" checksum="67B7F4EEE337191C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN80</accession>
    <name>B1KN80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tetraheme cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0276</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322926.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0276"/>
    <dbReference type="EnsemblBacteria" id="ACA84577">
        <property type="protein sequence ID" value="ACA84577"/>
        <property type="gene ID" value="Swoo_0276"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0276"/>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136713_1_1_6"/>
    <dbReference type="OMA" id="ELPCQEC"/>
    <dbReference type="OrthoDB" id="1683334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012286">
        <property type="entry name" value="Tetrahaem_cytochrome"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14537">
        <property type="entry name" value="Cytochrom_c3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764684" evidence="7">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_c3_2" evidence="8">
        <location>
            <begin position="33"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="117" mass="13441" checksum="E0B409633C11682D" modified="2008-04-29" version="1" precursor="true">MKMYKLMLGLVLAGLVSLSAQAIEQRDYHKEVIGKDCKSCHDQGVKNYPSDQACLQCHDVDELAEETARSEEDKWQNPHNNLHYGKELPCIECHGEHEAKKPICSNCHTFKYDKHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNA9</accession>
    <name>B1KNA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA methylase N-4/N-6 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0305</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322955.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0305"/>
    <dbReference type="REBASE" id="17468">
        <property type="entry name" value="M.SwoAII"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84606">
        <property type="protein sequence ID" value="ACA84606"/>
        <property type="gene ID" value="Swoo_0305"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0305"/>
    <dbReference type="eggNOG" id="COG2189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020164_1_1_6"/>
    <dbReference type="OMA" id="SLWITID"/>
    <dbReference type="OrthoDB" id="1487464at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="3">
        <location>
            <begin position="61"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="510" mass="57743" checksum="B6C2F4496F111088" modified="2008-04-29" version="1">MPILNWLNKEQSVTAARDCPYRLLEQVPELSYGEANTDNMLIQGDNLEALKALIPTHAGRVKCIFIDPPYNTKSAFEHYDDNLEHSHWLSMIYPRMELLHQLLADDGSIWITLDDNESHYMKVILDEIFGRKNFVANCIWQKLYTVKNSAKYLSDMHEHVLVYSKNKQIWERNLLPRTEKSASNYSNADDDKRGAWTTNAIQARNYYSLGTYEIVSPSGRKHVPPQGTFWRISEDSFKKLDSDNRIWWGKDGNNVPRVKKFLSEAKDGVVPATFWSYQDAGSNADAKKEVREVFNELDEIFITPKPEKLIQRILNIASKEGDLVLDSFLGSGTTSAVSAKMNRKFIGIELGEHAESLCVHRQKKVIDGEQGGISKDVAWQGGGGFNFYRLGEVIFNENGSLKEGISFNALASHIWYGDTRNSLDQKEKSPLLGVHNGTAYYLLYNGILGDKRPDGGNVLTSKVLAILPEHPLDAENGKKVIYGETSRMGSARLKSENIIFKQIPYDVRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI0</accession>
    <name>B1KNI0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ</fullName>
            <ecNumber evidence="4">2.1.1.200</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA Cm32/Um32 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmJ</name>
        <name evidence="6" type="ordered locus">Swoo_1773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(32) in tRNA = 2'-O-methyluridine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42936"/>
            <dbReference type="Rhea" id="RHEA-COMP:10107"/>
            <dbReference type="Rhea" id="RHEA-COMP:10290"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>cytidine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42932"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10289"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.200" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324403.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1773"/>
    <dbReference type="EnsemblBacteria" id="ACA86057">
        <property type="protein sequence ID" value="ACA86057"/>
        <property type="gene ID" value="Swoo_1773"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1773"/>
    <dbReference type="eggNOG" id="COG0565">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056931_0_1_6"/>
    <dbReference type="OMA" id="PIMNLSH"/>
    <dbReference type="OrthoDB" id="1637132at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004808">
        <property type="entry name" value="LasT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00050">
        <property type="entry name" value="rRNA_methyl_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="5">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="27932" checksum="548C7EF5979C27A5" modified="2008-04-29" version="1">MLSNIRVVLVGTSHPGNIGSTARAMKTMGLSTLYLAEPRVEPDGHSVALAAGASDILKHAVTVDSVAEAIADCSLVIATSARSRTLDWPMLEPREAGEKLVSSALTGPVAIVFGRENNGLTNEELQKCNYHVAIPANPEYTSLNLAQAVQIICYEARVAHLAQVQRDFENAKPADYVEPENEYPFASERENFFTHLEKTLLNTGFIVKQHPGQVMTKLRRLFSRARLEKQEMNILRGMLTSIDKKVATKDKSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNM6</accession>
    <name>B1KNM6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1819</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324449.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1819"/>
    <dbReference type="EnsemblBacteria" id="ACA86103">
        <property type="protein sequence ID" value="ACA86103"/>
        <property type="gene ID" value="Swoo_1819"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1819"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_6"/>
    <dbReference type="OMA" id="WGTYLVK"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034040">
        <property type="term" value="F:ATPase-coupled lipid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011917">
        <property type="entry name" value="ABC_transpr_lipidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02203">
        <property type="entry name" value="MsbA_lipidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="28"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="363"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="397"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="604" mass="66090" checksum="8E5D14086AB5E63C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNW9</accession>
    <name>B1KNW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PepSY-associated TM helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325913.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3308"/>
    <dbReference type="EnsemblBacteria" id="ACA87577">
        <property type="protein sequence ID" value="ACA87577"/>
        <property type="gene ID" value="Swoo_3308"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3308"/>
    <dbReference type="eggNOG" id="COG3182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025664_2_0_6"/>
    <dbReference type="OMA" id="HFDLHYM"/>
    <dbReference type="OrthoDB" id="1656356at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="541" mass="61525" checksum="7749F412579CCA3F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ1</accession>
    <name>B1KNZ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4773</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4773"/>
    <dbReference type="EnsemblBacteria" id="ACA89022">
        <property type="protein sequence ID" value="ACA89022"/>
        <property type="gene ID" value="Swoo_4773"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4773"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_1_4_6"/>
    <dbReference type="OMA" id="NQFIDDC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="94"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="18869" checksum="D049CA529592968D" modified="2008-04-29" version="1">MLSREQLQGLFRYCFCLTAEQRSAEDLLQTSLEKWIRRGQSVEYSHAYIRKIIRNQFVDDCRRNNAIAFESIEESAPILLDETCIEELEIQHNLIEHVFERLNTAEREVLYLWAVDGYTASQISQELMQPRGTILSRLHRIKQKVADISQSRPSKRSGVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP01</accession>
    <name>B1KP01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4783</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327349.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4783"/>
    <dbReference type="EnsemblBacteria" id="ACA89032">
        <property type="protein sequence ID" value="ACA89032"/>
        <property type="gene ID" value="Swoo_4783"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4783"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_6"/>
    <dbReference type="OMA" id="WQQSYGD"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="125"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="125"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="25335" checksum="7BDCB817D5FA46B8" modified="2008-04-29" version="1">MKILLVEDDATTIEYVVKGFTEQGHNIETASDGHQGLLLATSMKYDLILLDRMLPQLDGLKLLAALRATGSQTPVLILSALSHVDERVKGLRAGGDDYMTKPFAFSELLVRAEKLMQRGLSQPAETGLTVGNLVMELLTRKVTLDGNELMLQPKEFQLLKYLMEHPNQVISRTLLFEAVWDYHFDPRTNVIDVHIAKLRRKFEELGFGELIETVRGAGYRLRQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP33</accession>
    <name>B1KP33_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytoplasmic chaperone TorD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327381.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4815"/>
    <dbReference type="EnsemblBacteria" id="ACA89064">
        <property type="protein sequence ID" value="ACA89064"/>
        <property type="gene ID" value="Swoo_4815"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4815"/>
    <dbReference type="eggNOG" id="COG3381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077650_2_0_6"/>
    <dbReference type="OMA" id="QRHMGSW"/>
    <dbReference type="OrthoDB" id="1995553at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="25778" checksum="8AD33C5DD426C726" modified="2008-04-29" version="1">MTELVREVSENDQLRADIYQLLAALLRSQPSPELLQFLSDLEIDTEDDSEMTKAWLALKLAANQFSGEQLEDEYFNIFYGVGSGEIMPYGSWFMTGSLMDKPLALLRQDLMQLGFEREENVKEPEDHVAALCEVMGVLILEAPGYRQLAFYQRHIGSWIARFCDSLAKAPSAAFYATVAQLAKSFFEVEQSEFEQLQLDIPVNCPGSEAEKKAAESAVEKIEPSTSELAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP34</accession>
    <name>B1KP34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4816</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4816"/>
    <dbReference type="EnsemblBacteria" id="ACA89065">
        <property type="protein sequence ID" value="ACA89065"/>
        <property type="gene ID" value="Swoo_4816"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4816"/>
    <dbReference type="eggNOG" id="COG1145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022482_1_0_6"/>
    <dbReference type="OMA" id="CTLCMAC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="421"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="452"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="560" mass="61325" checksum="2507FD7695C50C52" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP51</accession>
    <name>B1KP51_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4833</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327399.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4833"/>
    <dbReference type="EnsemblBacteria" id="ACA89082">
        <property type="protein sequence ID" value="ACA89082"/>
        <property type="gene ID" value="Swoo_4833"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4833"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_2_3_6"/>
    <dbReference type="OMA" id="ATPGPNM"/>
    <dbReference type="OrthoDB" id="1440181at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA89082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="22292" checksum="7936A6BBD3F94D35" modified="2008-04-29" version="1" precursor="true">MLFDTWLLYFFAVLLIAVSPGTMAVLSMSHGIHFGKTRSLATALGSVTSALILMAASAAGLGALLSATEYGFTILKYCGAAYLLFLGIKLLLTKASSQGLDLQQIKSKGTPAQMFKQAFLVGISNPKDLLFFGALFPQFIDISAPQAPQLAILAITWAVIDFSFVMIYASMANVLAPTLKTSNKLHWFDRTSGGVFISLAAILVTREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP95</accession>
    <name>B1KP95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323014.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0365"/>
    <dbReference type="EnsemblBacteria" id="ACA84665">
        <property type="protein sequence ID" value="ACA84665"/>
        <property type="gene ID" value="Swoo_0365"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0365"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059523_1_2_6"/>
    <dbReference type="OMA" id="WYIIEQD"/>
    <dbReference type="OrthoDB" id="1194699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766922" evidence="1">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="51"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="284" mass="31692" checksum="83937588C25D27C9" modified="2008-04-29" version="1" precursor="true">MKAVLTSLIGFLMVISTTSMAHEAYSLTPPKVSVQLWSVKDQLKDDFEATVEALAQMGFDGVEFAGDFGPFNEDANGLRLYLDSLGMVASGAHVSFEQLNDENFTETVAFYQALGAKVLIVGWDKRAWDPKGIDFVVNELNRISLKLKPLGIKFGFHNHEHEFNGFKGTTFWDYLAKNTMQDVVLQQDVGWTTYAGRDPIEYVKRYPGRTITTHYKVKLPEGVEGKLPIIGQDTIDWLALTKANIAVGGTQWLVVEQEEYPNGLTPLQAVEKSKLGLDNILKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPG9</accession>
    <name>B1KPG9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex</fullName>
            <ecNumber evidence="5 10">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_1838</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="10">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="5 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324468.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1838"/>
    <dbReference type="EnsemblBacteria" id="ACA86122">
        <property type="protein sequence ID" value="ACA86122"/>
        <property type="gene ID" value="Swoo_1838"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1838"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_0_0_6"/>
    <dbReference type="OMA" id="MKVPSPG"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="12">
        <location>
            <begin position="105"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="396" mass="43006" checksum="7DFBB983F3A84614" modified="2008-04-29" version="1">MSIEIKVPVLPESVADATIATWHVQPGEQVTRDQNLVDIETDKVVLEVVAPEDGSIAEFLANEGDTVLGEAVIAKFTAGAVAGQEVTKAEAEATTPEAADDTNDALSPSVRRLLGEHGLEASQVKGTGAGGRITKEDVEAFVKSKSAAPAPTASAQVDVAPLAERSEKRVPMSRLRKTIANRLLEAKNSTAMLTTFNEVNMKPIMDIRKQYQEVFEKRHGIRLGFMSFYIKAVTEALKRFPEVNASIDGDDIVYHNYFDISIAVSTPRGLVTPVLRDTDTMSLADIERNVRELAIKGRDGKLTVDDMTGGNFTVTNGGVFGSLMSTPILNLPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRIIDGRESVGYLVAIKDFLEDPTRLLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPJ5</accession>
    <name>B1KPJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324494.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1864"/>
    <dbReference type="EnsemblBacteria" id="ACA86148">
        <property type="protein sequence ID" value="ACA86148"/>
        <property type="gene ID" value="Swoo_1864"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1864"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_6"/>
    <dbReference type="OMA" id="CLCPSVV"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="24988" checksum="2D7ADE3BE5145C24" modified="2008-04-29" version="1">MSKLAIITGGSRGIGYSIAEKFAQMGFSLILMAKTASNLASAKQGLLKINANISIETIAVDFSDSAAVESVAQTITKKHSNIDILVNSAGVLSIEFEHASAATLSTLFSVNCISTMVLTNAISEQMKQARSGYIINIASLAGKSHLPKIGAYAATKAALISYSESLYKHLLPHNVKVSCLCPSVVNTEMTDDGRIANQDKIQTDDLVNAVAYILSLGKGAQLPQLDIDCTPIALAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPL6</accession>
    <name>B1KPL6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324515.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1885"/>
    <dbReference type="EnsemblBacteria" id="ACA86169">
        <property type="protein sequence ID" value="ACA86169"/>
        <property type="gene ID" value="Swoo_1885"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1885"/>
    <dbReference type="eggNOG" id="COG5633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145387_0_0_6"/>
    <dbReference type="OMA" id="LYRFYWY"/>
    <dbReference type="OrthoDB" id="2082094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd09030">
        <property type="entry name" value="DUF1425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010824">
        <property type="entry name" value="DUF1425"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038483">
        <property type="entry name" value="YcfL-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07233">
        <property type="entry name" value="DUF1425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766927" evidence="1">
        <location>
            <begin position="19"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14135" checksum="8AD02740201EC781" modified="2008-04-29" version="1" precursor="true">MKKLITILVLGLMMTACAPHTAGVMASSTGEVRVDNGSFAGEVSVEQLKSRQQGGFLQGSGLIISKVATDLRLQYKFTWYDINGYTLDDEGSAWKSLKLHGKQQMQVSGLAPNTDAVRYELYVRKAFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPN8</accession>
    <name>B1KPN8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324537.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1907"/>
    <dbReference type="EnsemblBacteria" id="ACA86191">
        <property type="protein sequence ID" value="ACA86191"/>
        <property type="gene ID" value="Swoo_1907"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1907"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_396321_0_0_6"/>
    <dbReference type="OMA" id="RWRNVVK"/>
    <dbReference type="OrthoDB" id="1506986at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="575" mass="66699" checksum="4B00972D85517929" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPU6</accession>
    <name>B1KPU6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325964.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3360"/>
    <dbReference type="EnsemblBacteria" id="ACA87629">
        <property type="protein sequence ID" value="ACA87629"/>
        <property type="gene ID" value="Swoo_3360"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3360"/>
    <dbReference type="eggNOG" id="ENOG5031HD9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085417_0_0_6"/>
    <dbReference type="OMA" id="AYRVEYN"/>
    <dbReference type="OrthoDB" id="1970612at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010239">
        <property type="entry name" value="CHP02001"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09694">
        <property type="entry name" value="Gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02001">
        <property type="entry name" value="gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767286" evidence="1">
        <location>
            <begin position="22"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="26560" checksum="4C57FE73A73CB1C6" modified="2008-04-29" version="1" precursor="true">MNYLLKSLFAFLLFGLFPTQGQGEVNYFGYIAATTDHRAYGVSLTQKDPAMQLHAGLATENGFYVGTFISTFNFIDDASPYEAGENLETDLYAGYRFGLSEELVLSVTLYQYLIQGTDRGINLDFTELMIDLYSPYGQFSFSHTLNDILGDLSQDSAYRVEYNKTLALWDTGLSLDIQLGHWNTKDALGEAYLYYNLGISAPIGPVMACIAYNGTDNSGEALFGDIAEGTYYAKLTWAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ96</accession>
    <name>B1KQ96_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">2OG-Fe(II) oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0453</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323100.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84751">
        <property type="protein sequence ID" value="ACA84751"/>
        <property type="gene ID" value="Swoo_0453"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0453"/>
    <dbReference type="eggNOG" id="COG3751">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022206_1_0_6"/>
    <dbReference type="OMA" id="YPPGAFY"/>
    <dbReference type="OrthoDB" id="1139586at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="114"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="217" mass="24581" checksum="5CF754F1ADB8D545" modified="2008-04-29" version="1">MALHTGLEIDPSMDQYTSLFESIVQDVADNGYSIKTNALPVELAQKLSARAQAISDTHFKAAGIGRSNELMLDTQIRSDEICWIVGDSELGASWLNWVEGLKQYVNRTLFLGLDEFESHFAHYSEGDFYQKHKDAFRGESNRILTLVAYLNEDWSEECGGELLVYPDDSDEVIAKVAPHFGTIVVFMSEEFPHEVLPAKCDRYSIATWFRRKSDKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQF0</accession>
    <name>B1KQF0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fumarate reductase cytochrome b subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0508</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0508"/>
    <dbReference type="EnsemblBacteria" id="ACA84805">
        <property type="protein sequence ID" value="ACA84805"/>
        <property type="gene ID" value="Swoo_0508"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0508"/>
    <dbReference type="eggNOG" id="ENOG502ZBTX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075821_0_0_6"/>
    <dbReference type="OMA" id="EAMTWVA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00581">
        <property type="entry name" value="QFR_TypeB_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004224">
        <property type="entry name" value="Fum_red_B_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000177">
        <property type="entry name" value="Fumar_rd_cyt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="1 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000177-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="25690" checksum="5EE3505D6BABA04D" modified="2008-04-29" version="1">MAITKINNKAGEASKLKSWSEGKNWSGKLDISQSVSGVILALFLWTHLVLVSSILLGGDAMTWVAGVMELNFLSPDGHGYPWVVSLIATGVAALALVHVVVAITKLPMNLRQQLALKKQMSVINHGDTKLWVWQALTGVAILFLLPVHLWLIGAAPETIGPAGSADRIWNDGVWLLYLPLLVCVELHGAIGVYRVAIKWGAARDINTRARMKRVKTVISVVFVLIGIASLLAFLPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH2</accession>
    <name>B1KQH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidyl-dipeptidase Dcp</fullName>
            <ecNumber evidence="10">3.4.15.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1927</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.15.5" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324557.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1927"/>
    <dbReference type="EnsemblBacteria" id="ACA86211">
        <property type="protein sequence ID" value="ACA86211"/>
        <property type="gene ID" value="Swoo_1927"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1927"/>
    <dbReference type="eggNOG" id="COG0339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001805_4_0_6"/>
    <dbReference type="OMA" id="KRSGAWC"/>
    <dbReference type="OrthoDB" id="1935578at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43660">
        <property type="entry name" value="PTHR43660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767561" evidence="8">
        <location>
            <begin position="24"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="9">
        <location>
            <begin position="273"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="725" mass="80987" checksum="BEE07C4705C37B71" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ5</accession>
    <name>B1KQJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxylesterase</fullName>
            <ecNumber evidence="2">3.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1950"/>
    <dbReference type="EnsemblBacteria" id="ACA86234">
        <property type="protein sequence ID" value="ACA86234"/>
        <property type="gene ID" value="Swoo_1950"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1950"/>
    <dbReference type="eggNOG" id="COG0400">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049413_3_2_6"/>
    <dbReference type="OMA" id="WYDILAM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080030">
        <property type="term" value="F:methyl indole-3-acetate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="10"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="223" mass="24336" checksum="D1C3F67670F3CF14" modified="2008-04-29" version="1">MSTISLERITIEPQTKATACVIWLHGLGDSGAGFAPVVPALGLPQDHSIRFIFPHAPEQAVTINQGYIMRAWYDIKSMDLHNRADMQGVLGSEVSVKALIQEQIDSGIPADRIVLAGFSQGGVMSLFTGLRYPEKLAGIMALSCYLPTADKLPENLSVANLSTSILQHHGEQDDVVPVSSGKMANELLNDAGYKAEWKTYQMPHSVLPEQLRDIAKWLNSVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQP9</accession>
    <name>B1KQP9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2004</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324634.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2004"/>
    <dbReference type="EnsemblBacteria" id="ACA86288">
        <property type="protein sequence ID" value="ACA86288"/>
        <property type="gene ID" value="Swoo_2004"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2004"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_3_0_6"/>
    <dbReference type="OMA" id="YSAFSRM"/>
    <dbReference type="OrthoDB" id="1806723at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="257" mass="28878" checksum="C2120108E0061BFF" modified="2008-04-29" version="1">MEIANIKYWARDAYNLIYLDLLQFFRSKLIVISSLLTSVTMVLAFGLGADNGQPIVPIEGNYFAFILPGILAVGIMFSSTYTMGYTFIVDCQRRTIEDIVLSPLSYVGFIVSRIIGMSLKCSLQFLLVLMISMLFFNATIESYVLLFFAFFTECITFAALGIIVASFTNEISFSSLINIIIIPLSYFGGVFFPLDNFGSFSNVVSALPLAAHIEVFRDAMAATSSTDLYFNLLLTTFYSLTSIWVAMYVFKFRIQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR9</accession>
    <name>B1KQR9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9 11">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="3 9 11">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_3407</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 11">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="3 9 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326010.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3407"/>
    <dbReference type="EnsemblBacteria" id="ACA87675">
        <property type="protein sequence ID" value="ACA87675"/>
        <property type="gene ID" value="Swoo_3407"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3407"/>
    <dbReference type="eggNOG" id="COG1477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044403_2_1_6"/>
    <dbReference type="OMA" id="AFAKQCF"/>
    <dbReference type="OrthoDB" id="2021063at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="33048" checksum="00AD638A071BC409" modified="2008-04-29" version="1">MAKYRLTATPWGYMGEFSAMASPCELLIETDNKQIADAMMALACTETLRIEQKYSRFIKGNTLWQLNHSHPEAIELDQETTNLLQFAKHCFELSQGKFDITSGPLNALWRFDKQGKLPKESELCQARQSVGFSRLTLNRSQLTMPEGMMLDLGGIGKEYAADRVAHLLAHHWRDIAVLVNFGGDIACPIAKRFGEPEWQVGIENPEALDSAAEIVSIRQGGLATSGDTRRFIEINNKRFGHIINPKSGYPIEGAPRSVTVMADNCTTAGMLATMAMLEGDDAENFLAEQEVGFRVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR30</accession>
    <name>B1KR30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323195.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0551"/>
    <dbReference type="EnsemblBacteria" id="ACA84847">
        <property type="protein sequence ID" value="ACA84847"/>
        <property type="gene ID" value="Swoo_0551"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0551"/>
    <dbReference type="eggNOG" id="ENOG5031FQX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137390_1_1_6"/>
    <dbReference type="OMA" id="LMGPFMQ"/>
    <dbReference type="OrthoDB" id="2016615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021866">
        <property type="entry name" value="SpoIIAA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038396">
        <property type="entry name" value="SpoIIAA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11964">
        <property type="entry name" value="SpoIIAA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="121" mass="13383" checksum="286ED02CEA0962D7" modified="2008-04-29" version="1">MLCKIPDIAEGVISLFASGRLSSSDYQEKLKPLIEQSRGEAGKVFLYVEADVLLEGWDANSLTGSGEVRLDNFDALVLVGGPDWFGNAVRLMGPFMQSEVAWYPLEAKVEAIAWMTERLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG2</accession>
    <name>B1KRG2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Galactokinase</fullName>
            <ecNumber evidence="11">2.7.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Galactose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">galK</name>
        <name evidence="15" type="ordered locus">Swoo_2085</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13553"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28061"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324714.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2085"/>
    <dbReference type="EnsemblBacteria" id="ACA86369">
        <property type="protein sequence ID" value="ACA86369"/>
        <property type="gene ID" value="Swoo_2085"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2085"/>
    <dbReference type="eggNOG" id="COG0153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_2_1_6"/>
    <dbReference type="OMA" id="PVCYNLR"/>
    <dbReference type="OrthoDB" id="1388391at2"/>
    <dbReference type="BRENDA" id="2.7.1.2">
        <property type="organism ID" value="12548"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00246">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022963">
        <property type="entry name" value="Galactokinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019741">
        <property type="entry name" value="Galactokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00106">
        <property type="entry name" value="GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="6 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalKase_gal_bdg" evidence="14">
        <location>
            <begin position="12"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_N" evidence="12">
        <location>
            <begin position="114"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="13">
        <location>
            <begin position="279"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="35"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="124"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA86369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="385" mass="41688" checksum="8B2D6454DE937FE6" modified="2008-04-29" version="1">MSDLINKVSTVFEVGFHYQAQYVLQAPGRVNLIGEHTDYNDGYVLPCAINYCAVVCASPREDNLVRVISVDYDGATDEFSLDEDIIPTKNSWANYIRGVIKHLKLRGYQFGGADIAIGGDVPQGAGLSSSAALEVAIGQTFKALYRLDISQQEIALNGQEAENQFVGCNCGIMDQLISAEAKKDHALLIDCRNLATTPVALPKGNSIVIVNSNKKRGLVDSEYNTRRKQCETAARFFGVKALRDVDIDTFNAREPELDTLIAKRAKHIITENARTYAAAKAMASNDMQTLQRLMAESHASMRDDFEITVPEVDALVAIIKSEVGVLGGVRMTGGGFGGCVVSIVPDALVNQVINAVEAQYYEQSGLWASIYVCTAQIGAGSVFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK1</accession>
    <name>B1KRK1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3502"/>
    <dbReference type="EnsemblBacteria" id="ACA87766">
        <property type="protein sequence ID" value="ACA87766"/>
        <property type="gene ID" value="Swoo_3502"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3502"/>
    <dbReference type="HOGENOM" id="CLU_2081519_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="13818" checksum="D56852D32442CF1B" modified="2008-04-29" version="1">MKKKIRHITVDDKKYNWRVTSLNDQNVLLRIWVDGFKKFPWIEAKFPFRDPWLNFAELVAEHNGNYDVSSDNLFEGITPKKVRCIIEAVIRDKGIAGEINKPVSLDWSPKRLQATYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDP6</accession>
    <name>B1KDP6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2159</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324788.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2159"/>
    <dbReference type="EnsemblBacteria" id="ACA86443">
        <property type="protein sequence ID" value="ACA86443"/>
        <property type="gene ID" value="Swoo_2159"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2159"/>
    <dbReference type="eggNOG" id="COG0605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031625_0_0_6"/>
    <dbReference type="OMA" id="YLHSIFW"/>
    <dbReference type="OrthoDB" id="1440645at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="90"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="21418" checksum="D26E95389F5592B2" modified="2008-04-29" version="1">MAFELPALPYAKDALEPHISQETIEYHYGKHHNTYVVKLNGLVEGTELAEKSLEEIIKTSSGGIFNNAAQIWNHTFYWNCLSPNGGGAATGAVAKAIDDAFGSFEAFKAQFTDAAVNNFGSAWTWLVKNADGSVAIVNTSNAATPLTDSSVTPIMTVDVWEHAYYIDYRNVRPDYLAHYWELVNWDFVNQNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE18</accession>
    <name>B1KE18_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PKD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323351.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85004">
        <property type="protein sequence ID" value="ACA85004"/>
        <property type="gene ID" value="Swoo_0709"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0709"/>
    <dbReference type="eggNOG" id="ENOG5033S7Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_412715_0_0_6"/>
    <dbReference type="OMA" id="NIANGWF"/>
    <dbReference type="OrthoDB" id="1339457at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764739" description="PKD domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="502"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="665" mass="73025" checksum="8209B464B93DA8A3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE69</accession>
    <name>B1KE69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative phytochrome sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0760</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0760"/>
    <dbReference type="EnsemblBacteria" id="ACA85055">
        <property type="protein sequence ID" value="ACA85055"/>
        <property type="gene ID" value="Swoo_0760"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0760"/>
    <dbReference type="eggNOG" id="COG3604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_125_3_6"/>
    <dbReference type="OMA" id="LRYEAHQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="198"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="525" mass="57802" checksum="4E02A6E9DA170851" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF1</accession>
    <name>B1KEF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324872.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2248"/>
    <dbReference type="EnsemblBacteria" id="ACA86529">
        <property type="protein sequence ID" value="ACA86529"/>
        <property type="gene ID" value="Swoo_2248"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2248"/>
    <dbReference type="eggNOG" id="COG1026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_472295_0_0_6"/>
    <dbReference type="OMA" id="INASTHY"/>
    <dbReference type="OrthoDB" id="1965255at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="2">
        <location>
            <begin position="73"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="647" mass="73150" checksum="9605D3ACED8404A9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEL8</accession>
    <name>B1KEL8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326365.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3774"/>
    <dbReference type="EnsemblBacteria" id="ACA88033">
        <property type="protein sequence ID" value="ACA88033"/>
        <property type="gene ID" value="Swoo_3774"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3774"/>
    <dbReference type="eggNOG" id="ENOG502ZA13">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038472_0_0_6"/>
    <dbReference type="OMA" id="KGYYEAY"/>
    <dbReference type="OrthoDB" id="1753713at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043749">
        <property type="entry name" value="DUF5694"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18950">
        <property type="entry name" value="DUF5694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766992" evidence="1">
        <location>
            <begin position="20"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="358" mass="40637" checksum="DE0B8F766FD18F37" modified="2008-04-29" version="1" precursor="true">MYKLLVLVLSLSISHNVCAEQYIKSLNAKAKHKTDVMVLGSTHLNTIKVELNKDDFTPVIQMLETFNPTAVAIESLRAEDILTMLNGSEEHQAVLSQFVGDTLLSLAEKEQKALGVSANDAINKMNKLLAKNQFSQQKRIELIKLAIAGYNRDTAALHWSLLDASIPNDSLSKELQAFLHKQTNRNNEINVIAVELAERLDLNRLYPIDDHLDKDMFGNIASELMPSYQKSTFWAEFHSSEYITKPEKLKSQALETGDWLPLFYWFNSEEYQSDVINKEWLGFVDKDLDPKSALARVALWEIRNLNMASNIMRVVADHIDGRVVIIIGANHKVFLEQYLSNMVGVNIVQFEDYAPMSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEM6</accession>
    <name>B1KEM6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326372.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3782"/>
    <dbReference type="EnsemblBacteria" id="ACA88041">
        <property type="protein sequence ID" value="ACA88041"/>
        <property type="gene ID" value="Swoo_3782"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3782"/>
    <dbReference type="eggNOG" id="COG2352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_666894_0_0_6"/>
    <dbReference type="OMA" id="ESWLYQV"/>
    <dbReference type="OrthoDB" id="332963at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="406" mass="46041" checksum="DDEAA62E87649397" modified="2008-04-29" version="1">MSTNLHQAGVKLLKQLGRHADLIMDVYLSGSVSEDGENGAAIEKLRKAEILWRPEPEQELRLKRSVRALLEEALSDERNRQIDSNVGSSLASIKTLADHYKEARHNVDFGASEAYLADLNEHVYSFTEGLRYSIRVLWSRINNEFGYVGTINAKIRENELAQSQVTELLNGLEMFQFSELGEIAGDIRELRKLLVTTLQETLSDCTQELSVVQGRLLELLGRFRQIRGRTRLLKGWLLYTDLHPDYKPADHVSHKQLPTLFNRAEAILAPAAVDVHNTSYEPELLDIVSRIKAISRTSHEPVVREHDVSVSLSQSEDFAIPDNPLKLAVDGYFCSVIDSGRSQSALEYLQSNELPWDRESWLYQVICGYEGLPQEHKDYFELEPIGESDPVYTGNFIIRDVELGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW5</accession>
    <name>B1KEW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EAL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323463.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0821"/>
    <dbReference type="EnsemblBacteria" id="ACA85116">
        <property type="protein sequence ID" value="ACA85116"/>
        <property type="gene ID" value="Swoo_0821"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0821"/>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_131_3_6"/>
    <dbReference type="OMA" id="FKLDDFG"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="262"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="541" mass="61856" checksum="E9EE58672F3475DC" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFG8</accession>
    <name>B1KFG8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3885</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326473.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88143">
        <property type="protein sequence ID" value="ACA88143"/>
        <property type="gene ID" value="Swoo_3885"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3885"/>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016813_4_2_6"/>
    <dbReference type="OMA" id="CPERRHD"/>
    <dbReference type="OrthoDB" id="437016at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018270">
        <property type="entry name" value="C_nuclsd_transpt_met_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00804">
        <property type="entry name" value="nupC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="7">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="8">
        <location>
            <begin position="194"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="42954" checksum="3B25386D67DE8800" modified="2008-04-29" version="1">MEVFISLLGMFSLIGLAVLISEKRTAINLRTVLGALAFQIAFGAFVMYVPMGQSMLDSASGGVMHVIGYANEGLSFLFGDLAKFGVGFIFVINVLFVVVFVSALIAVLYYLGIMQLIIGLIGGGLSKLLGTSRAESLSATANIFVGPIEAPSMVRPFVKHMTRSELFAVMTGGLASVAGGTMIGYIQMGVDVKYVLTAAFMTAPAGLLFAKLIWPETEEPQNDIKKVMDEQDDRPANVLDAAAGGAAMGMQQVISVSALLLAFVALIAMVNGIIGGIGGWFGYGELTMQMILGYLLAPLAWIMGVPWSEAIQAASFIGQKMVINEFVAYIDFLKVADQLSEKTQIIISFTLCGFANIGSLAMVIGGLAALCPERRHDLSAIGMKALIAAALANLMSGTIAGLLFSLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI7</accession>
    <name>B1KFI7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome-c peroxidase</fullName>
            <ecNumber evidence="11">1.11.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3904</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="6">Binds 2 heme groups.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Binds 2 heme groups per subunit.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.5" evidence="11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326492.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3904"/>
    <dbReference type="PeroxiBase" id="5091">
        <property type="entry name" value="SwoDiHCcP02"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88162">
        <property type="protein sequence ID" value="ACA88162"/>
        <property type="gene ID" value="Swoo_3904"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3904"/>
    <dbReference type="eggNOG" id="COG1858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034652_1_1_6"/>
    <dbReference type="OMA" id="NMFQKFG"/>
    <dbReference type="OrthoDB" id="52724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026259">
        <property type="entry name" value="MauG/Cytc_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000294">
        <property type="entry name" value="Cytochrome-c_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764382" evidence="9">
        <location>
            <begin position="23"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="10">
        <location>
            <begin position="210"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="330" mass="36261" checksum="2B2CD5FE1E8ABDD7" modified="2008-04-29" version="1" precursor="true">MKHTIFCLLTLLFICDSVQADATENSIHAIAIKFFKPLPNKMPGGENDNDDKIALGKRLYFDNQLSINNTQSCNSCHNLLGTDENPGSGTDNLAVSFGALGSAGTRNSPTTWNAGLQFTQFWDGRANTLIEQAKFPILNPIEMALPSKEEAITRLTNTGYLALFIKAYPDEASPLNFHNILDALAAFQRTLISEDRFDLFLNGETNALSEKEKQGVMTFITAGCVACHNGPLLGGQMFTKMGVVNPYPNKIDRGRAHLTMSSADDFQFKVPSLRNVSKTAPYFHDGAETSLEQAVKDTGFHQLGITLSDKEVEDITSFLKTLDNIKVVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFJ9</accession>
    <name>B1KFJ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3916"/>
    <dbReference type="EnsemblBacteria" id="ACA88174">
        <property type="protein sequence ID" value="ACA88174"/>
        <property type="gene ID" value="Swoo_3916"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3916"/>
    <dbReference type="eggNOG" id="COG3542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088365_1_1_6"/>
    <dbReference type="OMA" id="ERSHWHR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06121">
        <property type="entry name" value="cupin_YML079wp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009327">
        <property type="entry name" value="Cupin_DUF985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039935">
        <property type="entry name" value="YML079W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387">
        <property type="entry name" value="PTHR33387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06172">
        <property type="entry name" value="Cupin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_5" evidence="1">
        <location>
            <begin position="12"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="18614" checksum="700751167100957F" modified="2008-04-29" version="1">MTDKLSLETADSFIEHLKLEQHVEGGYFRSSYRSDEQFDDTRPLWTSIYFLLRTGEVSNFHRLTADEMWYFHAGQSLTIYMIDEAGELTTAQLGLNFAAGERPQFLVPKGCIFGSAMNNPGFSLVGCMVSPGFTFDDFELFSQEWLLTQYPQHKEVITRLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFP6</accession>
    <name>B1KFP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323559.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85212">
        <property type="protein sequence ID" value="ACA85212"/>
        <property type="gene ID" value="Swoo_0919"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0919"/>
    <dbReference type="HOGENOM" id="CLU_2685823_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764826" evidence="1">
        <location>
            <begin position="29"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="74" mass="7936" checksum="C8A4BC2094A58630" modified="2008-04-29" version="1" precursor="true">MKNGKMMTFFKAALIGAVCTSGMSVAIAQSEGEMTLNVGQSIFELNKDKTKDKVVIIPTQGCPMEPCPGEQIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW7</accession>
    <name>B1KFW7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323630.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85283">
        <property type="protein sequence ID" value="ACA85283"/>
        <property type="gene ID" value="Swoo_0990"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0990"/>
    <dbReference type="eggNOG" id="ENOG5032H6B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_207317_0_0_6"/>
    <dbReference type="OMA" id="WKAGKPK"/>
    <dbReference type="OrthoDB" id="1961209at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="63" mass="7065" checksum="4DBFFB2F3C378035" modified="2008-04-29" version="1">MSSEYVNQVPSTKEPSLSCQSCERFTVIEGETICYHQGEIISLLPMPTEPKNISLSCKGWKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG40</accession>
    <name>B1KG40_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">META domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325089.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2470"/>
    <dbReference type="EnsemblBacteria" id="ACA86747">
        <property type="protein sequence ID" value="ACA86747"/>
        <property type="gene ID" value="Swoo_2470"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2470"/>
    <dbReference type="eggNOG" id="COG3126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085265_0_0_6"/>
    <dbReference type="OMA" id="YLDRRML"/>
    <dbReference type="OrthoDB" id="2029962at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039366">
        <property type="entry name" value="Pilotin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09619">
        <property type="entry name" value="YscW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764427" description="META domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="META" evidence="2">
        <location>
            <begin position="169"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="282" mass="30779" checksum="C66C8B789494207E" modified="2008-04-29" version="1" precursor="true">MQFKLKKLALLSSVLISAFALQACDSKTVTPNQDGSIADKQLTEKASVMKSLDVNVIYLDRRMLPPNAVLEVVLEDVSKADAASELIASQTVTELGAPPYTVSIGYDSSNILDKHRYSLRATIKAEDSLVFTSTTHIDPFAQNQASPIEIKLDRVVRDKAADVNANAEFSLTHWELMSLAESPVAMGEGDNALFIQFNSDKNAVNGFSGCNNFMGSFQTQEGKLTMGPVAGTRKMCAKGMEQEMAFLTALESFASYQVQGEILIVKNNMGKVVARFESRDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC4</accession>
    <name>B1KGC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4005</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326590.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4005"/>
    <dbReference type="EnsemblBacteria" id="ACA88261">
        <property type="protein sequence ID" value="ACA88261"/>
        <property type="gene ID" value="Swoo_4005"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4005"/>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_983163_0_0_6"/>
    <dbReference type="OMA" id="FRIFKVP"/>
    <dbReference type="OrthoDB" id="1704906at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766576" evidence="10">
        <location>
            <begin position="23"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="171"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="51"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="26575" checksum="736F3C748E3EEC74" modified="2008-04-29" version="1" precursor="true">MTPKRYFTFACLTALIQGGVIASQGKPPQLPAGVAMGSLQSVSIALSTPAAQASQTVDSKPVEKKVDQTAEISTTPEPKSKPSTPKTVVHQVAKHKKQVEQKRIDNNSASQTKPKSKITELNQQADTETLIADTEPKADLASKQVEAQAKQGVSQASIALSRPTFSVPPSRPSYPKLARKRGFEGTATIEVMFNQIGEQLSLTLINSSGFNLLDRAALSAVKSWQFAAPSPQTAYAYTVRVPVKFALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC8</accession>
    <name>B1KGC8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4009</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326594.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4009"/>
    <dbReference type="EnsemblBacteria" id="ACA88265">
        <property type="protein sequence ID" value="ACA88265"/>
        <property type="gene ID" value="Swoo_4009"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4009"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_0_3_6"/>
    <dbReference type="OMA" id="MQGVFGN"/>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="338" mass="35439" checksum="3DA3A12EC0B7A580" modified="2008-04-29" version="1">MENRAWLWPSILTFLVITCLLSIVTGPLQIAPLTSFSAVLNWATHLELGAVAPHEQLVINNVRLPRTLLAMTVGATLAQCGAVMQGLFRNPLADPGIIGVSSGAALGAAICIVLFPGSGEYSVAFGAFIAGLITTLVVYRLASSSSGTSVVLLLLSGVAIAALAGAGIGLLTYLADDMALRDLTLWQMGSIAGAQWQYVTLSLLALLLISWQFYRSSKALNALLLGEAEARHLGVEVDQLKFKLIFLCAVGVGISVAATGIIGFIGLVVPHIVRMIIGPDHKRLLPISAVLGAIILALADVGARSLVAPSELPVGLVTAMLGAPFFIFMLLKQKNRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL8</accession>
    <name>B1KGL8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323692.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1053"/>
    <dbReference type="EnsemblBacteria" id="ACA85346">
        <property type="protein sequence ID" value="ACA85346"/>
        <property type="gene ID" value="Swoo_1053"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1053"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1473543_0_0_6"/>
    <dbReference type="OMA" id="DLWVLSN"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="21796" checksum="0500AE6BFF6C2634" modified="2008-04-29" version="1">MEQVQVRKGFEISLLNEQSLEAFFNYLDEQLSESGQGEVPLFQPLSRSHTGMTDEMKLRFSQGLVTQYKEPGWRQIWVAKDCDGNIRGHIDLRGHPEDHTQHRALLGMGVHTQARRTGLGKRFIRTVEQWAIDESELVWLDLWVLSNNKPAIGLYESTGFKKLGEVEDMFRIDNESHHFTRMAKRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGP9</accession>
    <name>B1KGP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1084</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323723.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1084"/>
    <dbReference type="EnsemblBacteria" id="ACA85377">
        <property type="protein sequence ID" value="ACA85377"/>
        <property type="gene ID" value="Swoo_1084"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1084"/>
    <dbReference type="eggNOG" id="COG2268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013048_1_0_6"/>
    <dbReference type="OMA" id="ERQYDSE"/>
    <dbReference type="OrthoDB" id="387521at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031905">
        <property type="entry name" value="Flotillin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="PTHR13806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15975">
        <property type="entry name" value="Flot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="6">
        <location>
            <begin position="35"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="582"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="211"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="604" mass="66358" checksum="5D7E83D949D77A7F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV1</accession>
    <name>B1KGV1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325161.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2543"/>
    <dbReference type="EnsemblBacteria" id="ACA86820">
        <property type="protein sequence ID" value="ACA86820"/>
        <property type="gene ID" value="Swoo_2543"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2543"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_19_1_6"/>
    <dbReference type="OMA" id="TSMRQIT"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041586">
        <property type="entry name" value="PsrA_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17939">
        <property type="entry name" value="TetR_C_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="211" mass="23354" checksum="2673AB68249EA96B" modified="2008-04-29" version="1">MANRSDTKTRILDAAEKLFAERGFSETSLRLITSKAEVNLASVNYHFGSKKELIRAVLARYLDVFMPVASARIVTLQSSEEGASLNDIFSSLVEPLLDLNQLRAEGTSTFLQLLGRGYIESQGHLRWFITTHYGEHLTQFVKAVADSAPHIPPAEMFWRLHFTLGTVVFTMASADALTEIAAADFNEHNDIEAVIRKVIPYLSAGVSVPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV6</accession>
    <name>B1KGV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0381 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325166.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2548"/>
    <dbReference type="EnsemblBacteria" id="ACA86825">
        <property type="protein sequence ID" value="ACA86825"/>
        <property type="gene ID" value="Swoo_2548"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2548"/>
    <dbReference type="eggNOG" id="COG3691">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171181_1_0_6"/>
    <dbReference type="OMA" id="DTCNDCG"/>
    <dbReference type="OrthoDB" id="1863819at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005272">
        <property type="entry name" value="CHP00743"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04175">
        <property type="entry name" value="DUF406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="95" mass="10289" checksum="73DA9C79F88265BD" modified="2008-04-29" version="1">MKNIQESQSALVNDTCNDCGSYADIGAVIDEHDTQLSISFTGVDAKVEAEAVALKAKSRFDGVESEIKTDSDLTSLVIHFAYSAEKMIFQLENGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH87</accession>
    <name>B1KH87_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323741.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1102"/>
    <dbReference type="EnsemblBacteria" id="ACA85395">
        <property type="protein sequence ID" value="ACA85395"/>
        <property type="gene ID" value="Swoo_1102"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1102"/>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_7_3_6"/>
    <dbReference type="OMA" id="FTSMNNQ"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="71"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="16944" checksum="1BD776557A55A1D5" modified="2008-04-29" version="1" precursor="true">MKMLLAVVVIACVIFYFFTSMNNQKAAQENIKIGASFLAENKDNEGVVETLSGLQYKVLAKGDGTVHPKASDTVTVHYHGTLIDGTVFDSSVERGEPIAFPLNRVIKGWTEGVQLMVTGEKVRFFIPSTLAYGNRSTGKIVGGSVLIFDVELISID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHM0</accession>
    <name>B1KHM0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325245.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2628"/>
    <dbReference type="EnsemblBacteria" id="ACA86905">
        <property type="protein sequence ID" value="ACA86905"/>
        <property type="gene ID" value="Swoo_2628"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2628"/>
    <dbReference type="eggNOG" id="ENOG5032S32">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133267_0_0_6"/>
    <dbReference type="OMA" id="PVMCVDK"/>
    <dbReference type="OrthoDB" id="1768785at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14534" checksum="30C7AB38F0EAFF19" modified="2008-04-29" version="1">MIKMFKELLQMTSEQSAPQRLLFLFADAEATNPKKSKQHQRGTISPVMCVDKLPSELSSFDALVKEADSIAKQWNFVFVASLSGDNGVAPTTQEAEPFLNKMANDIETGNGVGRYVIFDRDENPIQLESHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP9</accession>
    <name>B1KHP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IucA/IucC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IucA/IucC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325274.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2658"/>
    <dbReference type="EnsemblBacteria" id="ACA86934">
        <property type="protein sequence ID" value="ACA86934"/>
        <property type="gene ID" value="Swoo_2658"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2658"/>
    <dbReference type="eggNOG" id="COG4264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018524_1_1_6"/>
    <dbReference type="OMA" id="HPWQWWN"/>
    <dbReference type="OrthoDB" id="856726at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007310">
        <property type="entry name" value="Aerobactin_biosyn_IucA/IucC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022770">
        <property type="entry name" value="FhuF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037455">
        <property type="entry name" value="LucA/IucC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34384">
        <property type="entry name" value="PTHR34384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06276">
        <property type="entry name" value="FhuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04183">
        <property type="entry name" value="IucA_IucC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IucA_IucC" evidence="2">
        <location>
            <begin position="131"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="FhuF" evidence="3">
        <location>
            <begin position="395"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="572" mass="65166" checksum="AD7BC3CB79F6DFA9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT3</accession>
    <name>B1KHT3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4155</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4155"/>
    <dbReference type="EnsemblBacteria" id="ACA88411">
        <property type="protein sequence ID" value="ACA88411"/>
        <property type="gene ID" value="Swoo_4155"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4155"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_443351_0_0_6"/>
    <dbReference type="OMA" id="IDWGSSV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="64"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="623" mass="70454" checksum="ED3B2D772D8B64D4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT6</accession>
    <name>B1KHT6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Thiol:disulfide interchange protein DsbD</fullName>
            <ecNumber evidence="19">1.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Protein-disulfide reductase</fullName>
            <shortName evidence="19">Disulfide reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">dsbD</name>
        <name evidence="21" type="ordered locus">Swoo_4158</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>[protein]-dithiol + NAD(+) = [protein]-disulfide + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>[protein]-dithiol + NADP(+) = [protein]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:18753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 19">Cell inner membrane</location>
            <topology evidence="4 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">Belongs to the thioredoxin family. DsbD subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.8" evidence="19"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326743.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4158"/>
    <dbReference type="EnsemblBacteria" id="ACA88414">
        <property type="protein sequence ID" value="ACA88414"/>
        <property type="gene ID" value="Swoo_4158"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4158"/>
    <dbReference type="eggNOG" id="COG4232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014657_3_0_6"/>
    <dbReference type="OMA" id="YYADWCV"/>
    <dbReference type="OrthoDB" id="1055204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase (NAD(P)) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02953">
        <property type="entry name" value="DsbDgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00399">
        <property type="entry name" value="DbsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035671">
        <property type="entry name" value="DsbD_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028250">
        <property type="entry name" value="DsbDN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036929">
        <property type="entry name" value="DsbDN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022910">
        <property type="entry name" value="Thiol_diS_interchange_DbsD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32234:SF0">
        <property type="entry name" value="PTHR32234:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11412">
        <property type="entry name" value="DsbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74863">
        <property type="entry name" value="SSF74863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 19" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="17 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12 19" id="KW-0249">Electron transport</keyword>
    <keyword evidence="16 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="14 19 21" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18 19" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 19" id="KW-0732">Signal</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 19" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009007466" description="Thiol:disulfide interchange protein DsbD" evidence="19">
        <location>
            <begin position="27"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="20">
        <location>
            <begin position="464"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="19">
        <location>
            <begin position="136"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="19">
        <location>
            <begin position="217"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="19">
        <location>
            <begin position="523"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ACA88414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="609" mass="66609" checksum="ED70B684447D896C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHX8</accession>
    <name>B1KHX8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326785.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4200"/>
    <dbReference type="EnsemblBacteria" id="ACA88456">
        <property type="protein sequence ID" value="ACA88456"/>
        <property type="gene ID" value="Swoo_4200"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4200"/>
    <dbReference type="eggNOG" id="ENOG5031EGA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2083257_0_0_6"/>
    <dbReference type="OMA" id="RYANSAY"/>
    <dbReference type="OrthoDB" id="2193192at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="14917" checksum="37C20E0FCB886399" modified="2008-04-29" version="1" precursor="true">MEHRYANSAYASMKLKRSITMKRILDLLIGFSIVILAVSILIAAVQTWGTAELFTGVVLGAEPVFWMGFSVWSLLFAGVILLIVLLWLTLAFSVIALVSALCIAAALVMIFTGFSLLWPVLLLLLATWGVSQASQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI11</accession>
    <name>B1KI11_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline dehydrogenase</fullName>
            <ecNumber evidence="7">1.1.99.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1196</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>A + choline = AH2 + betaine aldehyde</text>
            <dbReference type="Rhea" id="RHEA:17433"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15710"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323835.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1196"/>
    <dbReference type="EnsemblBacteria" id="ACA85489">
        <property type="protein sequence ID" value="ACA85489"/>
        <property type="gene ID" value="Swoo_1196"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1196"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_7_1_6"/>
    <dbReference type="OMA" id="NHFESCA"/>
    <dbReference type="OrthoDB" id="543793at2"/>
    <dbReference type="UniPathway" id="UPA00529">
        <property type="reaction ID" value="UER00385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008812">
        <property type="term" value="F:choline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019285">
        <property type="term" value="P:glycine betaine biosynthetic process from choline"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011533">
        <property type="entry name" value="BetA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01810">
        <property type="entry name" value="betA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="8">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="9">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="95"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="565" mass="62130" checksum="73EFECCE5398D64D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA4</accession>
    <name>B1KIA4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Periplasmic nitrate reductase, electron transfer subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Diheme cytochrome c NapB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_2679</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 2 heme C groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the NapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325295.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2679"/>
    <dbReference type="EnsemblBacteria" id="ACA86955">
        <property type="protein sequence ID" value="ACA86955"/>
        <property type="gene ID" value="Swoo_2679"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2679"/>
    <dbReference type="eggNOG" id="COG3043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103367_2_0_6"/>
    <dbReference type="OMA" id="KCMSCHA"/>
    <dbReference type="OrthoDB" id="1650975at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009061">
        <property type="term" value="P:anaerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005591">
        <property type="entry name" value="NapB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38604">
        <property type="entry name" value="PTHR38604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03892">
        <property type="entry name" value="NapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006105">
        <property type="entry name" value="NapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0574">Periplasm</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767371" description="Periplasmic nitrate reductase, electron transfer subunit" evidence="14">
        <location>
            <begin position="27"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA86955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="18250" checksum="C72B9B4953588165" modified="2008-04-29" version="1" precursor="true">MKTVKLVSIAALMSCSFAIFTGSAAAADAVSDVKIATLREAPLDVEPTPPAMQKVSNTDVKQSRNYPMQPPVIPHKIDGYQVDLKVNKCMACHDRKQTTDSQAPMVSVTHYMDRENNFLATLSPRRYFCTQCHVPQLEAKLLVENDFVDMDHLIEADSTKKAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA7</accession>
    <name>B1KIA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic nitrate reductase NapE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325298.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2682"/>
    <dbReference type="EnsemblBacteria" id="ACA86958">
        <property type="protein sequence ID" value="ACA86958"/>
        <property type="gene ID" value="Swoo_2682"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2682"/>
    <dbReference type="eggNOG" id="COG4459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_200276_0_1_6"/>
    <dbReference type="OMA" id="WMSQLIS"/>
    <dbReference type="OrthoDB" id="2017834at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010649">
        <property type="entry name" value="NapE_TorE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06796">
        <property type="entry name" value="NapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="52" mass="5454" checksum="C043ACC7C9F139F7" modified="2008-04-29" version="1">MSSTASEEKSVELKVFIFLTVFLAPLLSVILVSGLGFAIWFTQIIAGPPGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK5</accession>
    <name>B1KIK5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326828.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4245"/>
    <dbReference type="EnsemblBacteria" id="ACA88501">
        <property type="protein sequence ID" value="ACA88501"/>
        <property type="gene ID" value="Swoo_4245"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4245"/>
    <dbReference type="eggNOG" id="COG2239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037408_1_0_6"/>
    <dbReference type="OMA" id="TMTVAVR"/>
    <dbReference type="OrthoDB" id="1239195at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="144"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="208"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="49542" checksum="1D74E325BA388EE6" modified="2008-04-29" version="1">MPIEVLDNELTDQRLNQLTQALSSGMFVHVRNMLHDMAASDIAFILESSPPRTRQVLWQLIDQDQTGEILDELGEELKDNLIKQMSPERVAKAAEGMDTDDLAYILRSLPDSVFKQVLHSMRSQDRARVEQALAYPDDTAGSIMNTDTVTLRPDVNIDVILRYLRIRGKLPEATDTLYVVDKHDRLLGGVEIADLLTCDPNSSIRDIMDAELEGIPVGMSDNEVAQLFERHDWISAPVIGEDNQLLGRITIDDVVDVIRENAEHSMMGMAGMDDDADTFGPVLKSTLQRSLWLTINLFAALLAASVSNMFEGTLEQFATIAILMTIVPSMGGVAGNQTLALVIRGIALGQIGQSNSRWLIGKELAIGFLNGLLWSVLVFAAIWLWKGDLALGGLIGGAMLINMTVAGLAGACIPLLLKRMNIDPALAGGMVLTTVTDVIGLFAFLGLATFFLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY0</accession>
    <name>B1KIY0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323974.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1336"/>
    <dbReference type="EnsemblBacteria" id="ACA85628">
        <property type="protein sequence ID" value="ACA85628"/>
        <property type="gene ID" value="Swoo_1336"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1336"/>
    <dbReference type="eggNOG" id="COG0816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098240_3_0_6"/>
    <dbReference type="OMA" id="PNWDDIE"/>
    <dbReference type="OrthoDB" id="2075502at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="4"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15240" checksum="00C2254E04DD98A8" modified="2008-04-29" version="1">MSSQTVLGFDYGTKSIGIAIGQSLTGSANPLLSIKAVDGIPKWEEIGMLIEEWRPDLVVVGLPLNMDGSEQEMTQRAKKFANRISGRFGVKVETQDERLTTADAKTRLFEMGGYKALTKGQVDAMSAVLIVESYFESLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY4</accession>
    <name>B1KIY4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323978.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1340"/>
    <dbReference type="EnsemblBacteria" id="ACA85632">
        <property type="protein sequence ID" value="ACA85632"/>
        <property type="gene ID" value="Swoo_1340"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1340"/>
    <dbReference type="eggNOG" id="ENOG5032YB2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113282_2_0_6"/>
    <dbReference type="OMA" id="KPGIDKA"/>
    <dbReference type="OrthoDB" id="1557777at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025411">
        <property type="entry name" value="DUF4136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13590">
        <property type="entry name" value="DUF4136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766678" description="DUF4136 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4136" evidence="2">
        <location>
            <begin position="25"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="21116" checksum="89DD842EA99A4B18" modified="2008-04-29" version="1" precursor="true">MKQVKVVLAALSLCALSACSSMKTSSDYDPAANFSDVKTYAWVEKKTQDSSYHLDGLMDQRVRSAVDSQLSLKGVKLTEPSTADVLVNYLTKVDKKINVDTFNTNYGYNPYYGPRWGMSGSMHTQTTVREYEVGTLILDMVDRESGKLIWRGSVADTIRDKNTPEERIEVVNQAIAAMLMNYPPKPEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ66</accession>
    <name>B1KJ66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0319 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325422.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2811"/>
    <dbReference type="EnsemblBacteria" id="ACA87086">
        <property type="protein sequence ID" value="ACA87086"/>
        <property type="gene ID" value="Swoo_2811"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2811"/>
    <dbReference type="eggNOG" id="COG3110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073782_1_0_6"/>
    <dbReference type="OMA" id="AFQIWVI"/>
    <dbReference type="OrthoDB" id="1877964at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018635">
        <property type="entry name" value="UPF0319"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38108">
        <property type="entry name" value="PTHR38108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09829">
        <property type="entry name" value="DUF2057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25048" checksum="CA1C8D0C902AA8D6" modified="2008-04-29" version="1" precursor="true">MKHPLLTLALTGIIPLIFIAPAFAGNHLTLPKSAELLVVNGAEISKSSQVSLENGTNQIVFKYHTKYRSQGQDKRFSSEAIVLSFTAEDKALTLVLPSLRSSSQSDKFNLNPQVTIEDIQGDALPIQTGVLRKEGIQLGRNYSEEVLNYNQTDAPAALKELAPTSVVISIPPTSPQLELEVLKDKAPELKDQKNISRMLDFWYSQADETTRNSFKEKINRADTETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ97</accession>
    <name>B1KJ97_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326896.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4316"/>
    <dbReference type="EnsemblBacteria" id="ACA88569">
        <property type="protein sequence ID" value="ACA88569"/>
        <property type="gene ID" value="Swoo_4316"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4316"/>
    <dbReference type="eggNOG" id="ENOG5033C43">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157099_0_0_6"/>
    <dbReference type="OMA" id="LLMQIYQ"/>
    <dbReference type="OrthoDB" id="1877842at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12339" checksum="6B38EE636E458B53" modified="2008-04-29" version="1">MNQATKAALISAFICPGGGHFYLKRYNTGTLLSVVTLAALIYLLNQAIARAQDISQQIINGQLPLDLSVIYPLITQPPAAEQALYSNIALVAFATSWFIGVIDAYRLGAIADKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD2</accession>
    <name>B1KJD2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326930.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4351"/>
    <dbReference type="EnsemblBacteria" id="ACA88604">
        <property type="protein sequence ID" value="ACA88604"/>
        <property type="gene ID" value="Swoo_4351"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4351"/>
    <dbReference type="eggNOG" id="ENOG5031G2D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1980048_0_0_6"/>
    <dbReference type="OMA" id="LLAFQFW"/>
    <dbReference type="OrthoDB" id="1765058at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="14361" checksum="347651979302FFB9" modified="2008-04-29" version="1" precursor="true">MKKPTLALSIIMFLYAVLAAVATWRAINIQVIDLFSFGVIPVLIGLALRTSWAGIAFKVYLAIQTLGLTALAGTAIIAYQVSPEDVKVVFNNHEIPVPLIAITAGLLLAFQFWVAFSTSTKGYLEGHPSAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJF0</accession>
    <name>B1KJF0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326948.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4369"/>
    <dbReference type="EnsemblBacteria" id="ACA88622">
        <property type="protein sequence ID" value="ACA88622"/>
        <property type="gene ID" value="Swoo_4369"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4369"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_404851_0_0_6"/>
    <dbReference type="OMA" id="ITIHREA"/>
    <dbReference type="OrthoDB" id="1599002at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767403" evidence="1">
        <location>
            <begin position="30"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="679" mass="75620" checksum="15FE7F4029A14200" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJH6</accession>
    <name>B1KJH6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4396"/>
    <dbReference type="EnsemblBacteria" id="ACA88648">
        <property type="protein sequence ID" value="ACA88648"/>
        <property type="gene ID" value="Swoo_4396"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4396"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_1_2_6"/>
    <dbReference type="OMA" id="GNTYRES"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="27371" checksum="2DE2FA58F282E98B" modified="2008-04-29" version="1">MVLPECCLLFGGHESHQLEYAGEASAETTELKTALSELAARYDIYLVAGTIPVRSEDGRVYSRTYLFDNTGSTLGDYDKLHLFDVDVADGTKQYRESDTFCPGEKITVIDTPFGKLGLAICYDLRFPDLFRAMRLAGAELIALPSAFTKVTGEAHWQPLIQARAIETQCFILAAAQWGQHNQGSRETWGQSMIVDPWGRVQAEKREECGWVQATLDRSEQDKIRKHIPVAGHNRFSEPKLRKSN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM4</accession>
    <name>KYNU_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Kynureninase</fullName>
            <ecNumber evidence="1">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kynU</name>
        <name type="ordered locus">Swoo_1405</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-kynurenine = anthranilate + H(+) + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + H(+) + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the kynureninase family.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324043.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJM4"/>
    <dbReference type="SMR" id="B1KJM4"/>
    <dbReference type="STRING" id="392500.Swoo_1405"/>
    <dbReference type="EnsemblBacteria" id="ACA85697">
        <property type="protein sequence ID" value="ACA85697"/>
        <property type="gene ID" value="Swoo_1405"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1405"/>
    <dbReference type="eggNOG" id="COG3844">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_4_0_6"/>
    <dbReference type="OMA" id="TFPTDGY"/>
    <dbReference type="OrthoDB" id="1474443at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00329"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00334">
        <property type="reaction ID" value="UER00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061981">
        <property type="term" value="F:3-hydroxykynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="PTHR14084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000357012" description="Kynureninase">
        <location>
            <begin position="1"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01970"/>
        </source>
    </evidence>
    <sequence length="430" mass="48545" checksum="BCF6BDB84CF10CDC" modified="2008-04-29" version="1">MIFENTLAFAQQQDRNDPLAHYSDQFHHPVIDGKEVLYFTGNSLGLQPKTAKEHINQELEDWAKWGVEGHFHAVNPWVSYHEILTPASAELVGANESEVVCMNSLTTNLHLLFVSFYKPTAKRFKIISEAKMFPSDRYLLETQVRHHGLDPDDAIIEISPREGEYLIREEDIIAAVNDNADELALLFFGGVNYFTGQLFDMQRLTKAAHGVGALAGFDLAHAVGNVPMHLHDWDVDFAAWCTYKYLNSSAGNVGGIFVNDRHGNNTKINRFGGWWGHNKERRFLMENSFEPMTGAEGWQISNAPVMGMAILKSSLDIFHEAGIENLRAKSLKLTAYLEFVFNDIVNQFTDIKLEIITPTDPTQRGCQLSIKLVGTNKEFFEALTKAGVIADFREPDVIRLAPTPLYNSFEDVYLLGQTLKVLAQNWRQHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJP8</accession>
    <name>B1KJP8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1429</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324067.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1429"/>
    <dbReference type="EnsemblBacteria" id="ACA85721">
        <property type="protein sequence ID" value="ACA85721"/>
        <property type="gene ID" value="Swoo_1429"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1429"/>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_6_6"/>
    <dbReference type="OMA" id="WRNLWRQ"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="295"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="411" mass="45739" checksum="4CD2BB40EB8354F9" modified="2008-04-29" version="1" precursor="true">MLFKLAWRNLWRQKRRTLLTALALSLALFLSLFMRSMQEGSYENNIDNSARFSTGLLQLQNPEFSESQSIEDLLSAATDFIAPVTAPPLSPHITHYLPRIESFALASASERAKGVMVFGVEPEREDSYSGIADKLIAGEFIDADDKQVLVGEGLAQFLSIKVGDELVLYGQGYRGQTAAGLYKVKGIIHFPLAAMDNQLVYMPIKLAQTLYSTGEQVTSWVLHTDSLDAVAEIKSELVKVFGSKVNVRDWQQLSPEMAQQIAMDKAGGVFMMYLLYGVVGFGLFATILMMTLERQREFGVMLATGLLRRKLLGLIAIESGFIALIGVLIGLIITLPVVTYFHYHPIQLTGETAQLMLEMGWEPIIPMMLSFSLILDQVKIVLGLMFICLLYPLWRAYRIDLVSALKGDSYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJP9</accession>
    <name>B1KJP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1430</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1430"/>
    <dbReference type="EnsemblBacteria" id="ACA85722">
        <property type="protein sequence ID" value="ACA85722"/>
        <property type="gene ID" value="Swoo_1430"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1430"/>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_6_6"/>
    <dbReference type="OMA" id="VIVFMSA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="32"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="316"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="428" mass="46418" checksum="EEA5DB0B45C44D81" modified="2008-04-29" version="1">MGNNSQVVRKKAMTAQIVKLAWRNLWRNKIRTGIMLASMVFGLMGVVTMMGFLSGMYVSMIDNAIAWQTSDVQVQNRRYLEDPDINEVIVNPAALYSELERLPQVSAYSARVVADGMVASARANRGIRINGVNVTDEAAVTPIAAHIEQGTWLPETGRYPVVVSQKTAERLRLSLGSKVVLTFSDVNKDVTGAAFRVRGIYRSPSSSFDDANLYVRQQELSQLAGVEGVHEIAVLLDDSQGGDSFDNQGAKLVAQALRKVSSTQNQIRDWQQIQPMLATIISQMGVSNGVILLIFVTAMGFGIINVMLMSVFERTREFGVLMAVGMVKSKVFLLILLESCLLGVTGAGLGLLGSFAVIALLSQTGIPLGSMSEGLGAFGVDTTLYPVLKIGEYLGVFLTVVVASMLASLYPARQILKLRPVDAMSHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK74</accession>
    <name>B1KK74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4453</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327031.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4453"/>
    <dbReference type="EnsemblBacteria" id="ACA88705">
        <property type="protein sequence ID" value="ACA88705"/>
        <property type="gene ID" value="Swoo_4453"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4453"/>
    <dbReference type="eggNOG" id="COG4235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036074_3_2_6"/>
    <dbReference type="OMA" id="IFWQHAR"/>
    <dbReference type="OrthoDB" id="1539126at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="234" mass="25996" checksum="B47A207BAEC12AD5" modified="2008-04-29" version="1">MNSLAVGIVISLSVSVALIWRHHLQSAHLLLNETALGDEPHHPAKFSFSEIKIPAAVTITFLICCLSLYAQIGRFGEWDKGVVDEHIDYLIAADINKNARKVSEQPKSEIALLNLAQSYIAGGMYPEAINSLDELIALSGEAADLLGMKASAMYYRDNRTMSLDTELVLARALALDKFEFQSRLLKATHAYLNGQYEQAIEQWQLLLQSESQSFNRASINNAIFKAEQKIADRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC7</accession>
    <name>B1KKC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324113.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1479"/>
    <dbReference type="EnsemblBacteria" id="ACA85767">
        <property type="protein sequence ID" value="ACA85767"/>
        <property type="gene ID" value="Swoo_1479"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1479"/>
    <dbReference type="HOGENOM" id="CLU_2037105_0_0_6"/>
    <dbReference type="OrthoDB" id="2051148at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764606" evidence="1">
        <location>
            <begin position="23"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="123" mass="13947" checksum="C0DCB6B64DCDAA5C" modified="2008-04-29" version="1" precursor="true">MRMKIFLIGLLFSLSFMNSVTAATLVCSGKIDRLSYHSPNKFMLKLSSMNTPVFFCSPDMEWKVGGTSYVTGAETCKTMYSTFLAIKMTDKSITSMYFDGDQVPSSCNSWESWRQANIRHYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD9</accession>
    <name>B1KKD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324125.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1491"/>
    <dbReference type="EnsemblBacteria" id="ACA85779">
        <property type="protein sequence ID" value="ACA85779"/>
        <property type="gene ID" value="Swoo_1491"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1491"/>
    <dbReference type="eggNOG" id="ENOG5034BE3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_175610_0_0_6"/>
    <dbReference type="OrthoDB" id="2041988at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767153" evidence="1">
        <location>
            <begin position="21"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="107" mass="11940" checksum="E412B81A4D14AC0B" modified="2008-04-29" version="1" precursor="true">MFIRIITLVGLLLVSSISQAVENHCGEVQRLRVWAGGSDTYGIWVEYKANPSQCPGGFYIPHGANNKDYVFSIALAAKMAKESVCIQVYSHSTDIQNRCRINYIMNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF0</accession>
    <name>B1KKF0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324136.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1502"/>
    <dbReference type="EnsemblBacteria" id="ACA85790">
        <property type="protein sequence ID" value="ACA85790"/>
        <property type="gene ID" value="Swoo_1502"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1502"/>
    <dbReference type="eggNOG" id="ENOG502Z8GW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086944_0_0_6"/>
    <dbReference type="OMA" id="WHSHWVV"/>
    <dbReference type="OrthoDB" id="1111230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767154" evidence="1">
        <location>
            <begin position="23"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="26404" checksum="00A1457842C0DBA5" modified="2008-04-29" version="1" precursor="true">MKLIPIISILVFSSLSIGCASAHQAHSGGIKAKQQTDVIAPFDIIHAKISTEGNTAIFHIAVSENAGTSKPTKTGKLAGSRAFAYVWPTNIDSFEVGFEHQAGILALAVATHPDFDDTPLFDENRDGNTGNDGNIWHSHWVVLQPNEQCGKGALGVVDIPEGSKPRLPKTWPGLPILLDSPGWQPTINGETVEVRIPFDDIGVVNSAQFDGVTAGLRINVDVHAPLFCVVDVFDIASGDLSLPGKVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW8</accession>
    <name>B1KKW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327100.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4523"/>
    <dbReference type="EnsemblBacteria" id="ACA88774">
        <property type="protein sequence ID" value="ACA88774"/>
        <property type="gene ID" value="Swoo_4523"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4523"/>
    <dbReference type="eggNOG" id="COG2153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056607_3_1_6"/>
    <dbReference type="OMA" id="VVEQDCV"/>
    <dbReference type="OrthoDB" id="1777515at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="151" mass="17255" checksum="00F1892D3147F5E8" modified="2008-04-29" version="1">MQWSVLTFKQLNLDELYEVLKLRVDIFIVEQNCPYPELDNKDRDPQTRHLIGRNTQGDIVAYARILAPGVSYPDSSIGRVVVSEQARGGGVAHTLMQEAISLAAQYWPENDIQLGGQEYLKDFYQKLGFDPVSEVYLEDGIPHLDMLYKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL74</accession>
    <name>B1KL74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322764.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84415">
        <property type="protein sequence ID" value="ACA84415"/>
        <property type="gene ID" value="Swoo_0114"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0114"/>
    <dbReference type="eggNOG" id="ENOG5032FER">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_972851_0_0_6"/>
    <dbReference type="OMA" id="HEYPHFA"/>
    <dbReference type="OrthoDB" id="1247573at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027945">
        <property type="entry name" value="SseB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009839">
        <property type="entry name" value="SseB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07179">
        <property type="entry name" value="SseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14581">
        <property type="entry name" value="SseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SseB" evidence="1">
        <location>
            <begin position="14"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="SseB_C" evidence="2">
        <location>
            <begin position="177"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="286" mass="32391" checksum="578F35C024EF2632" modified="2008-04-29" version="1">MLNEKVPVVIHNTLEKVFESARLSNSKTDIESFYTELIQSPLYLLSDASDPADNEDAEELAGQGAQSISIMQWYIDLEDGDAFPFTPVFTSQQALDAAKTQMEKEGTEYHGQLELEASTVLQMLVNADSDIMLNPNTSLSKAIDENEIRYMLFPSVGLIEHRGQLQIVGEVLNAGLPLLDVLRQMLSSYSKVNAAYLIDSCRLDFQKSCSDHQFYLGLTFDDTDYADELSRIRSEIFNIHRKIELNGWDISIHLVETGDEMSEYLLAQTSPFYNRSLMSRIKSWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA5</accession>
    <name>B1KLA5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0145"/>
    <dbReference type="EnsemblBacteria" id="ACA84446">
        <property type="protein sequence ID" value="ACA84446"/>
        <property type="gene ID" value="Swoo_0145"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0145"/>
    <dbReference type="eggNOG" id="COG5652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144741_1_0_6"/>
    <dbReference type="OMA" id="LWVIYLA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="14966" checksum="28C39BCA32F81408" modified="2008-04-29" version="1" precursor="true">MFYKLTVSIALGFFAFILWAIYQANTGSSNLFFDLIQPLPYGDKLGHFGLFGLLTLLANLASRCRTLSIGRFKLYWGSTAVSLFVLIEELSQGLIPTRTLDMMDLAADGLGITLFSLLTYLIATNTRSQTAHEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC5</accession>
    <name>B1KLC5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphoribosylformylglycinamidine synthase</fullName>
            <shortName evidence="10">FGAM synthase</shortName>
            <shortName evidence="10">FGAMS</shortName>
            <ecNumber evidence="10">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Formylglycinamide ribonucleotide amidotransferase</fullName>
            <shortName evidence="10">FGAR amidotransferase</shortName>
            <shortName evidence="10">FGAR-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">purL</name>
        <name evidence="15" type="ordered locus">Swoo_1564</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324196.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1564"/>
    <dbReference type="MEROPS" id="C56.972"/>
    <dbReference type="EnsemblBacteria" id="ACA85850">
        <property type="protein sequence ID" value="ACA85850"/>
        <property type="gene ID" value="Swoo_1564"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1564"/>
    <dbReference type="eggNOG" id="COG0046">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0047">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001031_0_2_6"/>
    <dbReference type="OMA" id="LSANWMW"/>
    <dbReference type="OrthoDB" id="26038at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 10 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGAR-AT_N" evidence="14">
        <location>
            <begin position="35"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT_linker" evidence="13">
        <location>
            <begin position="170"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="12">
        <location>
            <begin position="430"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="12">
        <location>
            <begin position="836"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="1133"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="1258"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="1260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="676"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="677"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="720"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="884"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="886"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA85850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1293" mass="140602" checksum="F112D6F2F3CAB74B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG2</accession>
    <name>B1KLG2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal-body rod protein FlgF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324233.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1601"/>
    <dbReference type="EnsemblBacteria" id="ACA85887">
        <property type="protein sequence ID" value="ACA85887"/>
        <property type="gene ID" value="Swoo_1601"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1601"/>
    <dbReference type="eggNOG" id="COG4787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013687_1_0_6"/>
    <dbReference type="OMA" id="NLYFAIQ"/>
    <dbReference type="OrthoDB" id="947161at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012836">
        <property type="entry name" value="FlgF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02490">
        <property type="entry name" value="flgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="172"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="247" mass="26201" checksum="B0DDF4F216893AD0" modified="2008-04-29" version="1">MDKLLYVAMSGAKQNMNALAVRANNLANANTDGFKADMEQARSMQAFGEGLPTRVFAMTENPSANFSSGPIKTTGRDLDIAINGSGWIAVQGADGGEAYTRSGSLSFDTSGLLRNDRGNPIMGDSGPIVLPLPIEKVEIAQDGIISVRPLGATAEVIEEVGRIKLVNPGDGNMMRGADGLFRQMSGEIAPADPRVAVESGAVEGSNVNAVDEMVSLIDIQRQFEMQVKMMKTAEEMDQASSSLMRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLL3</accession>
    <name>B1KLL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325646.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3039"/>
    <dbReference type="EnsemblBacteria" id="ACA87310">
        <property type="protein sequence ID" value="ACA87310"/>
        <property type="gene ID" value="Swoo_3039"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3039"/>
    <dbReference type="eggNOG" id="COG2859">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077423_1_0_6"/>
    <dbReference type="OMA" id="YYYTKLA"/>
    <dbReference type="OrthoDB" id="1108674at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016907">
        <property type="entry name" value="UCP029033"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029033">
        <property type="entry name" value="UCP029033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="26417" checksum="A3252B926D8A8180" modified="2008-04-29" version="1" precursor="true">MLKNNTLAAFILGGLMSIGLVLSAQGIGNSLIKMKSMERTVTVKGLAEKEVKANIAIWPIRFTEVDNDLNALYASVQDKTDKVVGFLTAQGFTSDEISTSLPSIEDRQAQGYVDPNVKYRYAAKVTISLYTKRVDLLLSSQKSMLDLTKEGIAISNQDYNSRTEFLFTELNKVKPEMVQSATQNAREVATKFASDSDSRLGKIKQASQGQFSISDRDSNTPYIKRVRIVSTLTYYLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLL6</accession>
    <name>B1KLL6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325649.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3042"/>
    <dbReference type="EnsemblBacteria" id="ACA87313">
        <property type="protein sequence ID" value="ACA87313"/>
        <property type="gene ID" value="Swoo_3042"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3042"/>
    <dbReference type="eggNOG" id="COG4628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151208_1_0_6"/>
    <dbReference type="OMA" id="RIKIRCF"/>
    <dbReference type="OrthoDB" id="1457473at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018668">
        <property type="entry name" value="DNA-binding_VF530-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09905">
        <property type="entry name" value="VF530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="13622" checksum="3C6981F5C748887C" modified="2008-04-29" version="1">MTQANNPLHGIKLEALLTDLVEHYGWEGLADRIDVRCFKNDPSMKSSLRFLRKTLWAREKVEYLYLKMNKLPLPAKKPREDGYQSSDKALRKAANKRAENTTDSDKKADGQVNADIWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP1</accession>
    <name>B1KLP1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325674.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3067"/>
    <dbReference type="EnsemblBacteria" id="ACA87338">
        <property type="protein sequence ID" value="ACA87338"/>
        <property type="gene ID" value="Swoo_3067"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3067"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_417902_0_0_6"/>
    <dbReference type="OMA" id="GVYAPWC"/>
    <dbReference type="OrthoDB" id="81132at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50965">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NERD" evidence="2">
        <location>
            <begin position="10"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="418"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="656" mass="73401" checksum="3183DBB50D682722" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS2</accession>
    <name>B1KLS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phage shock protein C, PspC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3098</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325705.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3098"/>
    <dbReference type="EnsemblBacteria" id="ACA87369">
        <property type="protein sequence ID" value="ACA87369"/>
        <property type="gene ID" value="Swoo_3098"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3098"/>
    <dbReference type="eggNOG" id="COG1983">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137949_1_0_6"/>
    <dbReference type="OMA" id="MEAYVTS"/>
    <dbReference type="OrthoDB" id="2022704at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014320">
        <property type="entry name" value="Phageshock_PspC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02978">
        <property type="entry name" value="phageshock_pspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="7"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="132" mass="14753" checksum="1365D0D64B98A08C" modified="2008-04-29" version="1">MSKADGRTLYRIPQSGKVAGVCAGIADYFNFETWLVRVAAASIFLLGGGGPVLFIYILLWVILDAKPGTEKSDAKVKKDIEIKKKVWQAGEPAKMALRDVSENFRALETRLQKLERHVTSDNFDLKQEINNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW6</accession>
    <name>B1KLW6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4596"/>
    <dbReference type="EnsemblBacteria" id="ACA88846">
        <property type="protein sequence ID" value="ACA88846"/>
        <property type="gene ID" value="Swoo_4596"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4596"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_14_1_6"/>
    <dbReference type="OMA" id="FIHAQRA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="2"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="85" mass="9341" checksum="EA919663D30BC9ED" modified="2008-04-29" version="1">MMNLHNDIKQLIIDCLDLEDVTVDDIETEAPLFGEGLGLDSIDALELGLAIKKEFDVKIEANSEATKAHFYSVASLASFIESQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM45</accession>
    <name>B1KM45_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Competence protein ComF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0157"/>
    <dbReference type="EnsemblBacteria" id="ACA84458">
        <property type="protein sequence ID" value="ACA84458"/>
        <property type="gene ID" value="Swoo_0157"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0157"/>
    <dbReference type="eggNOG" id="COG1040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054549_0_2_6"/>
    <dbReference type="OMA" id="RYNQSAL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="274" mass="30690" checksum="9C43E5994B4CF663" modified="2008-04-29" version="1">MKQKMSAELESLWGQLVFRVSSMKSVLIRDWPLSSVFIKSIQWVSASLPNRCLMCHQSVLLPSRGLCSACLDSGLYHQPICQGCGCSMQVQTKFCGQCTKSQPLSVIAPCSYHQGLGRWIGAMKYQSQFAALPILSQALVCRVREMERLSLLQLPQVLIPVPLHAKRLRKRGFNQAWLIANEIYKQLNIPIVTNAVERVVDTRSQAGLTGKQRRHNLLSAFRLADDLPYQRVALIDDVVTTGTTAKEIASLLEKRHIHVQVWCLARAEAPGLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM60</accession>
    <name>B1KM60_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322822.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0172"/>
    <dbReference type="EnsemblBacteria" id="ACA84473">
        <property type="protein sequence ID" value="ACA84473"/>
        <property type="gene ID" value="Swoo_0172"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0172"/>
    <dbReference type="eggNOG" id="COG1999">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109681_2_0_6"/>
    <dbReference type="OMA" id="YFMRQIR"/>
    <dbReference type="OrthoDB" id="1720650at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="20110" checksum="B646E28AF95DACA4" modified="2008-04-29" version="1" precursor="true">MNSPKKSGKKPLLILLLVFILPVVAAKIVLSLDLYQGGATNKGELLTTGTSYSSLAMENPKPKEWQLLYLLPEICEQVCQDRLYILQQSHVALGREQDRVHTLILVNDKSDISALSNSPFETAKANNQMSEMLSQQQMIIVDPLGSLVMRYPSVSGREEQVLQGKSLVSDLRKMLKLSRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI2</accession>
    <name>B1KMI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324326.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1695"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85980">
        <property type="protein sequence ID" value="ACA85980"/>
        <property type="gene ID" value="Swoo_1695"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1695"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_0_0_6"/>
    <dbReference type="OMA" id="SEDIECW"/>
    <dbReference type="OrthoDB" id="865276at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="39547" checksum="6F8489CB88090334" modified="2008-04-29" version="1">MTPRVSVVMPIYNVQHFVKSAIDSVLSQSFTNFELILVNDCSTDQSLAICKTVLDHRIRIVNHEQNKGLAAARNSGIRHAIGRYVAFIDSDDMWHKDKLKMHVDHLNDSPRVGISFSRSSFMDHKGKRTEFYQMPQLKGITAADLLCRNPVGNGSAPVIRRETLNDIRFQALNHPEHYTCYFDERFRQSEDIECWLRIVATTHWKMEGIPEPLTYYRLNQQGLSSNIIKQLASWESMIDKAKLYAPKLLAKHEHNARAYQLRYLARQSIRNGSGKAAISLMNRALTESPSIMINETARTLVTFTAAYLLWLLPSSAYKVCENVGQSLLGFVQRNRISKDGVKSSMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ9</accession>
    <name>B1KMJ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ferredoxin-type protein NapF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">napF</name>
        <name evidence="8" type="ordered locus">Swoo_1712</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the cytoplasmic NapA precursor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NapF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324343.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1712"/>
    <dbReference type="EnsemblBacteria" id="ACA85997">
        <property type="protein sequence ID" value="ACA85997"/>
        <property type="gene ID" value="Swoo_1712"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1712"/>
    <dbReference type="eggNOG" id="COG1145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077329_2_1_6"/>
    <dbReference type="OMA" id="YQGIWCQ"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10564">
        <property type="entry name" value="NapF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02201">
        <property type="entry name" value="NapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004496">
        <property type="entry name" value="NapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24960:SF46">
        <property type="entry name" value="PTHR24960:SF46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00402">
        <property type="entry name" value="napF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="130"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="18065" checksum="1E0AE849FE88F3AD" modified="2008-04-29" version="1">MSNINQSRRRLFSRRKSNAIRPPWSRTDIEFTDICSRCDKCILSCETDIIIKGDGGFPEIDFKIDECTFCKKCAEVCPEAIFTDTNEQAWQLTATVNDTCLAHHGIWCQSCKDACDPRAITFKPEIGQAPRPNIDLNACTGCGACVAPCPNNSIILAASDNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN0</accession>
    <name>B1KMN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative thiol-disulphide oxidoreductase DCC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325744.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3137"/>
    <dbReference type="EnsemblBacteria" id="ACA87408">
        <property type="protein sequence ID" value="ACA87408"/>
        <property type="gene ID" value="Swoo_3137"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3137"/>
    <dbReference type="eggNOG" id="COG3011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092206_2_1_6"/>
    <dbReference type="OMA" id="ARNRYKW"/>
    <dbReference type="OrthoDB" id="2019103at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="15387" checksum="2C9FB49421AF822D" modified="2008-04-29" version="1">MEQKEIIIFDGVCNLCHGAVNFIINRDPECRFVFTPMQSDTAKELIASYNVDGEMGETFLLIKDNRCYMRTDAALEIAQSLSGLWPVFTIAKFLPRGIRDYFYRLLARNRYTLFGRRDTCILPTDAVLSRFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN3</accession>
    <name>B1KMN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Branched-chain amino acid transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325747.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3140"/>
    <dbReference type="EnsemblBacteria" id="ACA87411">
        <property type="protein sequence ID" value="ACA87411"/>
        <property type="gene ID" value="Swoo_3140"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3140"/>
    <dbReference type="eggNOG" id="COG4392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157896_1_2_6"/>
    <dbReference type="OMA" id="NRYAFLE"/>
    <dbReference type="OrthoDB" id="2078961at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11093" checksum="7D8C777C4F21B347" modified="2008-04-29" version="1">MIWLTIITMAILVFGSRYLFLEPKLPVRLSKNTLTFLSYSAPAVLTAIFAPIVFIREGELALSLDNSYLIAAVLAALLAYTTRNILLTTVVSMGLFFIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN76</accession>
    <name>B1KN76_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Quinone oxidoreductase, YhdH/YhfP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0272</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322922.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0272"/>
    <dbReference type="EnsemblBacteria" id="ACA84573">
        <property type="protein sequence ID" value="ACA84573"/>
        <property type="gene ID" value="Swoo_0272"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0272"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_26_3_6"/>
    <dbReference type="OMA" id="AQMDYNS"/>
    <dbReference type="OrthoDB" id="884088at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014188">
        <property type="entry name" value="Acrylyl-CoA_reductase_AcuI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF1">
        <property type="entry name" value="PTHR43677:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02823">
        <property type="entry name" value="oxido_YhdH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="11"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="34416" checksum="47058592E0EC372E" modified="2008-04-29" version="1">MFNALILTQEGKSTLANVGQLQVSDLPEGEVLVDVSCSSLNYKDGLAVTGTGRIIRNFPMVPGIDFAGVVVESSDKRYKAGDRVILTGWGVGENHWGGMAEKARVNADWLVPMPEACDAEKAMMIGTAGLTAMLCVQALQTANIQPDSGEILVTGASGGVGSVAVTLLARLGYKVVASTGRAEENSELLKSLGAAEVMERSELEQDARPLEKQRWAGVIDTVGNKVLATALAQMNYGGAAAICGLAGGFALPTTVMPFILRGVSLLGVDSVSCPFEKRQKAWEQVLSLLPESYYQQAGQTITLDQVPEFAGKIVKGEVTGRVLVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB1</accession>
    <name>B1KNB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322957.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0307"/>
    <dbReference type="EnsemblBacteria" id="ACA84608">
        <property type="protein sequence ID" value="ACA84608"/>
        <property type="gene ID" value="Swoo_0307"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0307"/>
    <dbReference type="eggNOG" id="ENOG5032S4J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1824010_0_0_6"/>
    <dbReference type="OMA" id="EVWKATQ"/>
    <dbReference type="OrthoDB" id="1681399at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="88"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="141" mass="16251" checksum="F2BE84637943AA29" modified="2008-04-29" version="1">MANGIQLAQENVERFELWIASQTDSDFKQIVYRGRLNRAEVAKGAGFAKSVLRQNPRIKHLLEELELNLRKRAVLPESIETKNQSKAYDQTENKSIREKQRLTSLEQEMIALKAENTLLRRKLSRFEELSSVLADLGRLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE5</accession>
    <name>B1KNE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Allophanate hydrolase subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1737</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1737"/>
    <dbReference type="EnsemblBacteria" id="ACA86022">
        <property type="protein sequence ID" value="ACA86022"/>
        <property type="gene ID" value="Swoo_1737"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1737"/>
    <dbReference type="eggNOG" id="COG2049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020207_1_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010016">
        <property type="entry name" value="KipI_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34698">
        <property type="entry name" value="PTHR34698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHS1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="24975" checksum="A6806E6DB21BAAAB" modified="2008-04-29" version="1">MDIKIINESSLIIYFGDEITPENGALVSQACNIILEELSSIVIDYIPSYCSLHLSFDISRFNILSIRTDIQNMLSCQRNIVTIDSGLVIEIPSYYDTEVGLDLNNVAEESGLSINEVIQCHSQVIYQVYAIGFAPGFAYMGNVDKGISLPRKKTPRTKVPKGSIAIAESQTAIYPTESPGGWHVLARTPIELIDFNSENLTPLSVGNRVKFVPINRIEYLKMGGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF0</accession>
    <name>B1KNF0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1742</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324373.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1742"/>
    <dbReference type="EnsemblBacteria" id="ACA86027">
        <property type="protein sequence ID" value="ACA86027"/>
        <property type="gene ID" value="Swoo_1742"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1742"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_62_4_6"/>
    <dbReference type="OMA" id="SHWVMWE"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="40"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="361"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="394"/>
            <end position="401"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="609" mass="67337" checksum="BC6F3BD6DB649BC8" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNG2</accession>
    <name>B1KNG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1754"/>
    <dbReference type="EnsemblBacteria" id="ACA86039">
        <property type="protein sequence ID" value="ACA86039"/>
        <property type="gene ID" value="Swoo_1754"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1754"/>
    <dbReference type="HOGENOM" id="CLU_204002_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="52" mass="6458" checksum="84283F99AE7D0263" modified="2008-04-29" version="1">MMWNWFSKFIGIKESQQRQRVEFDIPFELYHCRKEKFSIESSDHCDEENNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNG6</accession>
    <name>B1KNG6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ordered locus">Swoo_1759</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324389.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1759"/>
    <dbReference type="EnsemblBacteria" id="ACA86043">
        <property type="protein sequence ID" value="ACA86043"/>
        <property type="gene ID" value="Swoo_1759"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1759"/>
    <dbReference type="eggNOG" id="COG0341">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050012_1_0_6"/>
    <dbReference type="OMA" id="AFEWRMA"/>
    <dbReference type="OrthoDB" id="410730at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="315" mass="34014" checksum="7E7D7E8A8A79C4BE" modified="2008-04-29" version="1" precursor="true">MYQILSIKGTINFLRHALPISMLSLLLVLGSLTSLATKGINWGLDFTGGTVVELEFSSPIDLEILRGKLTSVETDGAVVQNFGSSRDVLTRLPVKEGVATDTQVAQVMEAATALDPQVIQKRVEVVGPQIGKELAEQGGLAVLVALICILIYVSFRFEWRLALGSVAALAHDVIITLGVFSLLQLDFDLTVLAGVLTVVGYSLNDTIVVFDRIRENFLKMRKSSPEEVVNTSITQTMSRTIITTGTTLVVVVALFLKGGTMIHGFATALLMGIFVGTFSSIYVASFLAIKLGINREHMMPVEIEKEGADQDALMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNG9</accession>
    <name>B1KNG9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="3">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1762</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324392.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1762"/>
    <dbReference type="EnsemblBacteria" id="ACA86046">
        <property type="protein sequence ID" value="ACA86046"/>
        <property type="gene ID" value="Swoo_1762"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1762"/>
    <dbReference type="eggNOG" id="COG1648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_8_0_6"/>
    <dbReference type="OMA" id="RTEANIH"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028161">
        <property type="entry name" value="Met8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037115">
        <property type="entry name" value="Sirohaem_synt_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019478">
        <property type="entry name" value="Sirohaem_synthase_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330">
        <property type="entry name" value="PTHR35330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10414">
        <property type="entry name" value="CysG_dimeriser"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sirohm_synth_M" evidence="8">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="CysG_dimeriser" evidence="7">
        <location>
            <begin position="150"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="34275" checksum="192AA8CD80348CE7" modified="2008-04-29" version="1">MQYFPLFVDTTKLNVLLIGAGEVASRKLELLGRTEACIKVIAIETSDEVQGYADKKRITLIQRAVVEEDIADVDIIYLATANEALNGHLADLATARGIWVNVVDSPELCRFITPSIVDRGRLQVAISTAGAAPVFARELRSRIESWLPPSLADLFDFVAEHRKEVQDRLPEFKARKLFWEHFFRSNGDRFDDKTLQRYEDSFQGLTAQGEILLIDDCTSIVMLPISAMPLMQRLDHIFSDIELPFTLNELVRRDATRENLVAISELTHRLEKGKRSLVFADRDKISQLKAHFPMAKHLKAGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI8</accession>
    <name>B1KNI8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2Fe-2S ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324411.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1781"/>
    <dbReference type="EnsemblBacteria" id="ACA86065">
        <property type="protein sequence ID" value="ACA86065"/>
        <property type="gene ID" value="Swoo_1781"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1781"/>
    <dbReference type="eggNOG" id="COG0633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082632_5_2_6"/>
    <dbReference type="OMA" id="SACGGVC"/>
    <dbReference type="OrthoDB" id="1837979at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018298">
        <property type="entry name" value="Adrenodoxin_Fe-S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011536">
        <property type="entry name" value="Fdx_isc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="PTHR23426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00355">
        <property type="entry name" value="ADRENODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02007">
        <property type="entry name" value="fdx_isc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00814">
        <property type="entry name" value="ADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12380" checksum="17E1B4BF090887B9" modified="2008-04-29" version="1">MPQIVFLPHEELCPDGAVVEAAEGETVLDVALRNGIHIEHACEKSCACTTCHVIIREGFDELEESDELEDDMLDKAWGLEPESRLSCQSKVPSTDLVVDIPKYTINMVSEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNN1</accession>
    <name>B1KNN1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325825.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3219"/>
    <dbReference type="EnsemblBacteria" id="ACA87489">
        <property type="protein sequence ID" value="ACA87489"/>
        <property type="gene ID" value="Swoo_3219"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3219"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090620_0_0_6"/>
    <dbReference type="OMA" id="LRNCPYA"/>
    <dbReference type="OrthoDB" id="1997747at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="90"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="25640" checksum="A4124D6D17B2CF45" modified="2008-04-29" version="1">MPLPILYSLQHCPYAMRARMGLLLANQRVLLLAIVMKNKPQAMLEISPKGTVPVLIVEDSNTTEVIDESLDIMLWALKRDDPHELLYPQTPETLPQMLELIEYNDKVFKPLLEQYKSAKRYHKDSELYDRSQCEVFIKQLELKLNQHQFIMGDTLSLADYALLPFVRQFARADRHKYLAAPYPKLQHWLKAHLDSPLFSKAMAKYSLWLDSGEEHLFGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNN2</accession>
    <name>B1KNN2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11 14">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="6 11 14">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_3220</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 14">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11 14">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 14">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="6 11 14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325826.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3220"/>
    <dbReference type="EnsemblBacteria" id="ACA87490">
        <property type="protein sequence ID" value="ACA87490"/>
        <property type="gene ID" value="Swoo_3220"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3220"/>
    <dbReference type="eggNOG" id="COG0362">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024540_4_2_6"/>
    <dbReference type="OMA" id="VIMVKAG"/>
    <dbReference type="OrthoDB" id="1245550at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="11 14" id="KW-0521">NADP</keyword>
    <keyword evidence="8 11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10 11 14" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="15">
        <location>
            <begin position="211"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="13">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="13">
        <location>
            <begin position="218"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA87490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="517" mass="56563" checksum="FF8358C66EE069D9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ8</accession>
    <name>B1KNQ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3246</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325852.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3246"/>
    <dbReference type="MEROPS" id="C82.A01"/>
    <dbReference type="EnsemblBacteria" id="ACA87516">
        <property type="protein sequence ID" value="ACA87516"/>
        <property type="gene ID" value="Swoo_3246"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3246"/>
    <dbReference type="eggNOG" id="COG3034">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102842_0_1_6"/>
    <dbReference type="OMA" id="IYAMVRD"/>
    <dbReference type="OrthoDB" id="1654458at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767248" description="YkuD domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="24"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="18033" checksum="6C0E27D998F38B8B" modified="2008-04-29" version="1" precursor="true">MNASKYIALICLFVAHFSFAGVDLVKVDKSESKMYLLDSGQIVKEYDVAFGANPKGHKVQEGDEKTPEGTYTLDYKKEDSSFYRAMHISYPNKQDIENAAKRGVSPGGFIMVHGQRNWLGWFAPITQSFNWTNGCIALSNSEMDEFMDLVSLGTEIQIEW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS9</accession>
    <name>RNH2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease HII</fullName>
            <shortName evidence="1">RNase HII</shortName>
            <ecNumber evidence="1">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rnhB</name>
        <name type="ordered locus">Swoo_3267</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNase HII family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325873.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNS9"/>
    <dbReference type="SMR" id="B1KNS9"/>
    <dbReference type="STRING" id="392500.Swoo_3267"/>
    <dbReference type="EnsemblBacteria" id="ACA87537">
        <property type="protein sequence ID" value="ACA87537"/>
        <property type="gene ID" value="Swoo_3267"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3267"/>
    <dbReference type="eggNOG" id="COG0164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036532_3_2_6"/>
    <dbReference type="OMA" id="YPTKLHL"/>
    <dbReference type="OrthoDB" id="1685277at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51975">
        <property type="entry name" value="RNASE_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000091656" description="Ribonuclease HII">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="RNase H type-2" evidence="2">
        <location>
            <begin position="18"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01319"/>
        </source>
    </evidence>
    <sequence length="213" mass="23354" checksum="88C333896C7CA063" modified="2008-04-29" version="1">MAVFKGITPEQIESLSSGLHAGVDEVGRGPLVGNVVTAAVILDPNNPITGLNDSKKLTEKKRELLFAEIHEKALCINVGHATPDEIDELNILHATMLAMQRAVAGLDIKPLSVLVDGNRTPAFYHGEETEDRIEAHAVVKGDGLISAISAASIIAKVIRDREMDLLDMEYPQYGFAKHKGYPTKAHFEALELHGVLPEHRKSFRPVKERLAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP32</accession>
    <name>B1KP32_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Formate dehydrogenase region TAT target</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327380.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4814"/>
    <dbReference type="EnsemblBacteria" id="ACA89063">
        <property type="protein sequence ID" value="ACA89063"/>
        <property type="gene ID" value="Swoo_4814"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4814"/>
    <dbReference type="eggNOG" id="ENOG5033B11">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180794_1_0_6"/>
    <dbReference type="OMA" id="DHVRSYY"/>
    <dbReference type="OrthoDB" id="2090824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014177">
        <property type="entry name" value="Formate_DH_TAT-contain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036704">
        <property type="entry name" value="UCP036704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02811">
        <property type="entry name" value="formate_TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764708" evidence="2">
        <location>
            <begin position="36"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="65" mass="6789" checksum="6E9866C67B695838" modified="2008-04-29" version="1" precursor="true">MKKQASDMGRRQLLKALAVGSAAGAVATVSGQAMAASPSEEPVMAKGDGYQETDHVRSYYASLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP36</accession>
    <name>B1KP36_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327384.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4818"/>
    <dbReference type="EnsemblBacteria" id="ACA89067">
        <property type="protein sequence ID" value="ACA89067"/>
        <property type="gene ID" value="Swoo_4818"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4818"/>
    <dbReference type="eggNOG" id="ENOG5032ZV5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144863_0_0_6"/>
    <dbReference type="OMA" id="KHVNRRK"/>
    <dbReference type="OrthoDB" id="1901670at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021736">
        <property type="entry name" value="DUF3305"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11749">
        <property type="entry name" value="DUF3305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="17717" checksum="D984332784C2085E" modified="2008-04-29" version="1">MQHTESQWPMHVSLKRIEKQVGRWTSISWELDQVLPATCEAPEGSKLIMLELHKDERGSYRINLDMDNAMLYVVCDELEDGTWIPAMISADQNVAAGCLEGDTPVLNLSMPEAVACWIEAFITRHGEVEICAHRRKHVNRRKNEGPSNNNQFGQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP98</accession>
    <name>B1KP98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323017.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0368"/>
    <dbReference type="EnsemblBacteria" id="ACA84668">
        <property type="protein sequence ID" value="ACA84668"/>
        <property type="gene ID" value="Swoo_0368"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0368"/>
    <dbReference type="eggNOG" id="ENOG502Z7MB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1140750_0_0_6"/>
    <dbReference type="OMA" id="SDEAMTH"/>
    <dbReference type="OrthoDB" id="1574258at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027056">
        <property type="entry name" value="Gluconate_2DH_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13618">
        <property type="entry name" value="Gluconate_2-dh3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="247" mass="27163" checksum="EF72E1A950A8B606" modified="2008-04-29" version="1" precursor="true">MSLVKRYSSKKPYLASLSRRDAIKWIGALSVTAAFPGLTACSSQALAPQSELAKGHWPQLELPVINATGYGKDPNLIIAPRASWPRTLTAAQLTFIAIFADIVAPREGSVPSASEVKVPDLLDEWVSAPYERQQQDRVSFLHLLAWLDEEARRRFDNLFVDVTASQQLAIIDDIAYKKAMQSEEFVRPAKAFADFRRLVLACFFCSPAGVKDIGYLGNVPIVGDYPGPSDEAMTHLQGVLDELGLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPB6</accession>
    <name>B1KPB6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323035.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84686">
        <property type="protein sequence ID" value="ACA84686"/>
        <property type="gene ID" value="Swoo_0387"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0387"/>
    <dbReference type="eggNOG" id="ENOG5033MTI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150629_1_0_6"/>
    <dbReference type="OMA" id="NIYGSHF"/>
    <dbReference type="OrthoDB" id="2044112at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="14554" checksum="8DD89F32019B446F" modified="2008-04-29" version="1" precursor="true">MKYGYLLLVILLLSGCLNIPPPQRGYTAPANNVCSVIAGATIVASDGQYLGKITNQYDSDSVLNDYGSYGGSYSATSIWNQYGSYGGEYSANSPFNEFSSSPPRIVKGGSVIGYLSVNQSLANSLNPYVIKSCKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD2</accession>
    <name>B1KPD2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323051.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0403"/>
    <dbReference type="EnsemblBacteria" id="ACA84702">
        <property type="protein sequence ID" value="ACA84702"/>
        <property type="gene ID" value="Swoo_0403"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0403"/>
    <dbReference type="eggNOG" id="COG5429">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065609_1_0_6"/>
    <dbReference type="OMA" id="YVVRKME"/>
    <dbReference type="OrthoDB" id="1505781at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010634">
        <property type="entry name" value="DUF1223"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36057">
        <property type="entry name" value="PTHR36057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06764">
        <property type="entry name" value="DUF1223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="29204" checksum="7BEE79E90D6010DB" modified="2008-04-29" version="1">MRFLVFLLIIFSWDSYGEQSLVDFKKQSKTTQPYIIELYTSQGCSSCPPAESWLSGFVERDTLWQEYFPLAFHVTYWDYIGWKDPFGQRGFSQRQYDHLNAKNTGQVYTPQFVINGEEWRGWFARDLLLGFNRQEQEVGVLKVAVNDKKLKASFLAAKKVKSDSLKLHMALVGIGLNTYVRKGENRNVRLLHNFTVLEHQIFEPSGLTAGGDELLFSGDVANFNMQKGSPESLALVAWVEQEGKAIQAVGDWLSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPJ6</accession>
    <name>B1KPJ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">7,8-diamino-pelargonic acid aminotransferase</fullName>
            <shortName evidence="4">DAPA AT</shortName>
            <shortName evidence="4">DAPA aminotransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">7,8-diaminononanoate synthase</fullName>
            <shortName evidence="4">DANS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diaminopelargonic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bioA</name>
        <name evidence="6" type="ordered locus">Swoo_1865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate</text>
            <dbReference type="Rhea" id="RHEA:16861"/>
            <dbReference type="ChEBI" id="CHEBI:16490"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="EC" id="2.6.1.62"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis; 7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.62" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324495.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1865"/>
    <dbReference type="EnsemblBacteria" id="ACA86149">
        <property type="protein sequence ID" value="ACA86149"/>
        <property type="gene ID" value="Swoo_1865"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1865"/>
    <dbReference type="eggNOG" id="COG0161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_4_3_6"/>
    <dbReference type="OMA" id="ARRHVFE"/>
    <dbReference type="OrthoDB" id="478143at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00834">
        <property type="entry name" value="BioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005815">
        <property type="entry name" value="BioA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00508">
        <property type="entry name" value="bioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="124"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="326"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM" evidence="4">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="49805" checksum="DC6A3ADA556326F9" modified="2008-04-29" version="1">MNNYINSTITANNSSIDFEFDKQHIWHPYTSMSHALPAFGVISAKECELTLDDGRQLVDGTSSWWACVHGYSHPTIVNAMQEQLHKLSHVMFGGITHQPAIELSKKLVNMTSDNLTKVFLADSGSIAVEVALKMSLQYWQGRNQPQKQRILTVKCGYHGDTFAAMSVCDPEGGMHTMFGDSVTQHEFVSAPQTQFGQPFDNSELDEMRAKLSSQGNEIAAVILEPVLQGAGGMRFYHPQYLVGLRQLCDEFNVLLILDEIATGFGRTGKLFAYEHATHDGKAVEADILCLGKALTGGYISLAATICSDEVAQGISDSPAGVFMHGPTFMGNPLACSAACASLDLLSRNEWQAQVSNIERQLQSELAEAIEYPQVKDVRVLGAIGVIEMNSSVNTAELQQQFVDLGVWIRPFSNLIYIMPPYVISAEQLTKLTSAMKIVAKSILTCGDQAEFISHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPR8</accession>
    <name>B1KPR8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325937.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87601">
        <property type="protein sequence ID" value="ACA87601"/>
        <property type="gene ID" value="Swoo_3332"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3332"/>
    <dbReference type="eggNOG" id="ENOG5033EB7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2940647_0_0_6"/>
    <dbReference type="OMA" id="GKWFHYD"/>
    <dbReference type="OrthoDB" id="2006573at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="61" mass="6957" checksum="119EA5062326B877" modified="2008-04-29" version="1">MELLPNCYTDLCINGKWFHYDHGELSVFMLNGGDPLTFELVSLPKTEDELEQHLTVISGNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPV3</accession>
    <name>B1KPV3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RHH_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325971.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3367"/>
    <dbReference type="EnsemblBacteria" id="ACA87636">
        <property type="protein sequence ID" value="ACA87636"/>
        <property type="gene ID" value="Swoo_3367"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3367"/>
    <dbReference type="eggNOG" id="COG4321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155738_2_1_6"/>
    <dbReference type="OMA" id="ITRSIRI"/>
    <dbReference type="OrthoDB" id="1837705at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3990.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027373">
        <property type="entry name" value="RHH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038268">
        <property type="entry name" value="RHH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13467">
        <property type="entry name" value="RHH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_4" evidence="1">
        <location>
            <begin position="16"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="10181" checksum="3E29491DE863579C" modified="2008-04-29" version="1">MCQIFSQQPIEHYQYITRAIRIDGHATSVKLELSFWEILEQIANNQEMSVPKFISNIYKESMAHNGGVTNLASILRCSCLIYLKQSTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW2</accession>
    <name>B1KPW2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OmpA domain protein transmembrane region-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325980.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3376"/>
    <dbReference type="EnsemblBacteria" id="ACA87645">
        <property type="protein sequence ID" value="ACA87645"/>
        <property type="gene ID" value="Swoo_3376"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3376"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106646_1_0_6"/>
    <dbReference type="OrthoDB" id="2018542at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764733" evidence="1">
        <location>
            <begin position="23"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="10"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="177" mass="18989" checksum="4755C65EDA3A69C7" modified="2008-04-29" version="1" precursor="true">MKKILMTGSALLTLFLATSATAAPDIQGYYIGAMGGYGELEANEFNESAASYGGYAGYSFGKDLAIESTFFTTANLADEGDVKARAVTLAAKLNHFFSPTYSMFIKIGVASTDVSAGIDDYSATGWIWGAGFNMAITDNVNVRLGYEVILTDLEHDTSDDIIDSELANLYLGINYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW6</accession>
    <name>B1KPW6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325984.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3380"/>
    <dbReference type="EnsemblBacteria" id="ACA87649">
        <property type="protein sequence ID" value="ACA87649"/>
        <property type="gene ID" value="Swoo_3380"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3380"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_6"/>
    <dbReference type="OMA" id="HHQQVVP"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="26008" checksum="D46AAE79F7B77AE9" modified="2008-04-29" version="1">MRILLVEDDIELQTNLKQHLLDANYTVDVASDGEIGLFQGCEYRYDAGIIDVGLPKMDGIALITTLREKEIDFPILILTARDSWQDKVEGLDAGADDYLTKPFQPEELVARLKALIRRSAGKASPLIHNGPFSINTSSLEVKKGERLITLSGSEYKLFEYFMLHPGEVKSKTVLTEHIYDQDFDLDSNVIEVFIRRLRKKLDPDNQYGLIETLRGQGYRLATLTTDKASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPZ9</accession>
    <name>B1KPZ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327429.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4863"/>
    <dbReference type="EnsemblBacteria" id="ACA89112">
        <property type="protein sequence ID" value="ACA89112"/>
        <property type="gene ID" value="Swoo_4863"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4863"/>
    <dbReference type="eggNOG" id="COG1725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_10_4_6"/>
    <dbReference type="OMA" id="IFEMFSI"/>
    <dbReference type="OrthoDB" id="1860081at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="125" mass="13990" checksum="1E1679CA77A96820" modified="2008-04-29" version="1">MLEQINVNPSSGEPIYRQLSEQIVRLIVGGQLQAEQVLPSVRQMAEHLSVNPMTVSRAIQQLVEQGWLERRRGQATRVATREVDENSSSLELVKPQVTALVSQAKQLGITPDELTSLIESCWKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ20</accession>
    <name>B1KQ20_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c oxidase accessory protein CcoG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4884</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327450.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4884"/>
    <dbReference type="EnsemblBacteria" id="ACA89133">
        <property type="protein sequence ID" value="ACA89133"/>
        <property type="gene ID" value="Swoo_4884"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4884"/>
    <dbReference type="eggNOG" id="COG0348">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032118_0_0_6"/>
    <dbReference type="OMA" id="EMVFRRI"/>
    <dbReference type="OrthoDB" id="1230380at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014116">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_FixG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032879">
        <property type="entry name" value="FixG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13746">
        <property type="entry name" value="Fer4_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11614">
        <property type="entry name" value="FixG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02745">
        <property type="entry name" value="ccoG_rdxA_fixG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA89133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="480" mass="55152" checksum="044823F3772C3D9A" modified="2008-04-29" version="1">MSTESNKKDYSKANRIKIHQPDANKADRFNPRNRIYVRAVEGLWSRLRTRLGWVAMLFFLILPWIPWGDRQAVWFNLAEQKFHIFGLTIWPQDLTLLAALLMIAAFGLFFVTTYLGRVWCGYTCPQTVWTFIFIWFEEKLEGARNKRMKLDQMPWSFNKLWRKTAKHASWVLISLITAMTFVSYFVPTREVYIDVFTLSASGGIYFWVVLFTLATYGNAGWMREIMCIHMCPYARFQAAMFDKNTYIVGYDTKRGESRGPRSRKADPKEMGLGDCIDCDLCVQVCPTGIDIRNGLQYECINCGACIDACDTTMERMGYDKGLIAYTTENKLDGIKEKVLRPKLVGYGVVLTVMILIFVYASATIAPVRVDVIRDRNQLFRENNEGLIENTFTLKILNKTEQEHHYQLSVEGLPEYIWYGAQEVKIDGGEVLTLPISVAVDPVDLSRTMTKINFKVVAEPSSTDSNSEKIEATQESRFFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ22</accession>
    <name>B1KQ22_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-dihydroxy-2-naphthoyl-CoA synthase</fullName>
            <shortName evidence="3">DHNA-CoA synthase</shortName>
            <ecNumber evidence="3">4.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menB</name>
        <name evidence="4" type="ordered locus">Swoo_4886</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327452.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4886"/>
    <dbReference type="EnsemblBacteria" id="ACA89135">
        <property type="protein sequence ID" value="ACA89135"/>
        <property type="gene ID" value="Swoo_4886"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4886"/>
    <dbReference type="eggNOG" id="COG0447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_7_6"/>
    <dbReference type="OMA" id="IFKQTDA"/>
    <dbReference type="OrthoDB" id="1275789at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01934">
        <property type="entry name" value="MenB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="PTHR43113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01929">
        <property type="entry name" value="menB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="91"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="144"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA89135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="33682" checksum="598EFC26F60F3E03" modified="2008-04-29" version="1">MSQQVSDIFDPNLWDQVSGFDFEDITYHRAKDQGTVRIAINRPECRNSFRPKTVDELFTALDHARQWSDVGCVLLTGNGPSAKDGGWAFCAGGDQRIRGKDGYKYEGEEANSADIARMGRLHILEVQRLIRFMPKIVIAVVPGWAVGGGHSLHVVCDLTLASKEHAIFKQTDPDVASFDSGYGSAYLAKMIGQKRAREIFFLGFNYSADEAFDMGMVNRSIPHAELETEALNWAREINSKSPTAMRMLKYGFNMADDGLVGQQLFAGEATRLAYGTSEAQEGRDAFLEKRDQDFSKFPWHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQF7</accession>
    <name>B1KQF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ppx/GppA phosphatase</fullName>
            <ecNumber evidence="2">3.6.1.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.1.40" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323160.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0515"/>
    <dbReference type="EnsemblBacteria" id="ACA84812">
        <property type="protein sequence ID" value="ACA84812"/>
        <property type="gene ID" value="Swoo_0515"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0515"/>
    <dbReference type="eggNOG" id="COG0248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025908_1_1_6"/>
    <dbReference type="OMA" id="IGCVRMT"/>
    <dbReference type="OrthoDB" id="1862004at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008894">
        <property type="term" value="F:guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="1">
        <location>
            <begin position="21"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="33552" checksum="4F8F2EEF790BD9D0" modified="2008-04-29" version="1">MPTTPLYAAITLGSNSFNMLVAKTLGGRPEIIAKYKRKVRLAEGIQSDGSLSEEVMLRGLDCLSMFSDMLKKEGVSVDNIAVIATATLRHIANSDEFCRRALPILGHPIEIISGMREAELIYQGMVATTEGEGRRLVIDIGGASTEFIIGDGDKVLLKTSLPMGCVTFNDKFFTSFPFQKLDFDDAKAAVKSALGDYLSELKHLGWHCVVGASGSVQSVVELLNYRQEPASITLDVLTSLQEEVLTQSSPSMLSISGLHQERAPTFAAGISILLALFELLEIESLNLSGGALREGVLQTLAQRIEQVADSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQF8</accession>
    <name>B1KQF8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0516</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323161.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0516"/>
    <dbReference type="EnsemblBacteria" id="ACA84813">
        <property type="protein sequence ID" value="ACA84813"/>
        <property type="gene ID" value="Swoo_0516"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0516"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_1_6"/>
    <dbReference type="OMA" id="GWDPRDP"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766952" evidence="5">
        <location>
            <begin position="27"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="50"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="395"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="909" mass="98951" checksum="C76726E45069146C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQG7</accession>
    <name>B1KQG7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324552.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1922"/>
    <dbReference type="EnsemblBacteria" id="ACA86206">
        <property type="protein sequence ID" value="ACA86206"/>
        <property type="gene ID" value="Swoo_1922"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1922"/>
    <dbReference type="HOGENOM" id="CLU_2397970_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="93" mass="10514" checksum="8ADC79D7DAB45FE5" modified="2008-04-29" version="1">MFTTPEIVKSLRLSQGYSVTELASKMGCSRQTIYNWEDGVSEPKLSQFLHLCVIVGLNPNNLLPKIPSKMSKTQITDKEFQDDNQQSSTDFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI0</accession>
    <name>B1KQI0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome-c peroxidase</fullName>
            <ecNumber evidence="11">1.11.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1935</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="6">Binds 2 heme groups.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Binds 2 heme groups per subunit.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.5" evidence="11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324565.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="PeroxiBase" id="5027">
        <property type="entry name" value="SwoDiHCcP01"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86219">
        <property type="protein sequence ID" value="ACA86219"/>
        <property type="gene ID" value="Swoo_1935"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1935"/>
    <dbReference type="eggNOG" id="COG1858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034652_1_0_6"/>
    <dbReference type="OMA" id="NTCHNVM"/>
    <dbReference type="OrthoDB" id="52724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026259">
        <property type="entry name" value="MauG/Cytc_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000294">
        <property type="entry name" value="Cytochrome-c_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764756" evidence="9">
        <location>
            <begin position="23"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="10">
        <location>
            <begin position="38"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="10">
        <location>
            <begin position="190"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="330" mass="35745" checksum="02C27753360BB706" modified="2008-04-29" version="1" precursor="true">MKLFSPIALAILAAICASPAMAKEPIEIIKPANITEPEKVELGKMLFFEPRLSKSGFISCNSCHNLSTGGVDALPTSIGHNWQEGPINSPTVLNAEYGLAQFWDGRAKDLKEQAGGPIANPKEMGFSHELAVSTIDSMPAYKTRFENVYGDGKITIDNITDAIAAFEKTLVTPNSPFDLYLQGDKSAITTEATAGYQLFKDKGCVSCHNGPAVGGTMYMKMGLVKPFHTKNPAEGRIAVTGNAADMHVFKVPTLRNIELTYPYFHDGATWTLEEAVNVMADIQLGQSLTEQETKEMVAFLKSLTGDQPQIILPILPPSNVNTPRPVPFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQL2</accession>
    <name>B1KQL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1967</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324597.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1967"/>
    <dbReference type="EnsemblBacteria" id="ACA86251">
        <property type="protein sequence ID" value="ACA86251"/>
        <property type="gene ID" value="Swoo_1967"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1967"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_1_0_6"/>
    <dbReference type="OMA" id="ASFTWVF"/>
    <dbReference type="OrthoDB" id="1945085at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="202" mass="22372" checksum="1AF79237806A01FF" modified="2008-04-29" version="1" precursor="true">MQETLWTLMLSAAFFCATMSMTPGPNNILLAQSGANYGIKRSLPHILGIRAGQTCLHISVLLGLGSLFDIWPMFHHVLKMLSIGYLLYLAYRISTAAVSDDPAAQESKPMTLKEAALFQLINPKSWMATITLCSAFTVTGEAYWLSGLLGMIVFNLVGFPASFTWVLLGSTIRRQLNSARRRSHFNWSMGFLLLLTIPLIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQL6</accession>
    <name>B1KQL6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1971</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324601.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1971"/>
    <dbReference type="EnsemblBacteria" id="ACA86255">
        <property type="protein sequence ID" value="ACA86255"/>
        <property type="gene ID" value="Swoo_1971"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1971"/>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_12_0_6"/>
    <dbReference type="OMA" id="RVIAGWD"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PTHR45779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="21"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12449" checksum="4B4ED90BA8D1B6CD" modified="2008-04-29" version="1">MISELIITDLEIGEGKEAVKGALITAHYVGCLEDGTQFDSSYAKGRPFQCVIGTGRVIKGWDQGMMGMKVGGKRKLFVPSHLAYGEREIGAHIKPNSDLHFEIELLEVLTRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQP4</accession>
    <name>B1KQP4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1999</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324629.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1999"/>
    <dbReference type="EnsemblBacteria" id="ACA86283">
        <property type="protein sequence ID" value="ACA86283"/>
        <property type="gene ID" value="Swoo_1999"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1999"/>
    <dbReference type="eggNOG" id="COG1032">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021572_4_5_6"/>
    <dbReference type="OMA" id="PFDEEFA"/>
    <dbReference type="OrthoDB" id="973846at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034466">
        <property type="entry name" value="Methyltransferase_Class_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01123">
        <property type="entry name" value="methyltransferase_(Class_B)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="4">
        <location>
            <begin position="199"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="506" mass="57383" checksum="B4B235564C8CB542" modified="2008-04-29" version="1">MKVLLISTNKIRVPRPALPIGMAYISSALKQAGHEVHVLDLLWEARELKAVLEKLKSHDFDLIGIAVRNLDNLTFIDPIFFGPLTRKIVQCVRKYTNAKVVIGGSGFSVEPKPFFEYAEPDFGVAGEGEKSIVELAEYIMNGKGKLEEISGLCYIRDGKFMQNPSFGSVDVSTVEPDRSIYDPQYFVDTISSSTDLTRDTQPAIETLQTKRGCKLYCSYCIIKKTEGRGNRFKEPALVANEIKQAMLNNPQVKEFEIVDATFNAPLDYATEVCEAMVRAKLTTPWYCQLSPTAITKEFVDLLARAGCIRVDLGTDAFSEEGLEHLIKGFDQSRVVEVDKILSASKLEHTHCVFLGAPGETPKVLKDSIEFSMKYLKPNQIYANLGIRIFGNTKLQRIAVKKGIIQKNHNMFLPTFYVEPETLACADTLNYVRDTYLNHKNWYLWWGLKGQTLVDRSKETIKIVQDMHEEYEYEMRNVPRFDDWQNTALIGNDVGQWNTNKIEIKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR4</accession>
    <name>B1KQR4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Na(+)-translocating NADH-quinone reductase subunit D</fullName>
            <shortName evidence="14">Na(+)-NQR subunit D</shortName>
            <shortName evidence="14">Na(+)-translocating NQR subunit D</shortName>
            <ecNumber evidence="14">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">NQR complex subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NQR-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">nqrD</name>
        <name evidence="15" type="ordered locus">Swoo_3402</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell inner membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326005.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3402"/>
    <dbReference type="EnsemblBacteria" id="ACA87670">
        <property type="protein sequence ID" value="ACA87670"/>
        <property type="gene ID" value="Swoo_3402"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3402"/>
    <dbReference type="eggNOG" id="COG1347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046659_1_1_6"/>
    <dbReference type="OMA" id="YLANEMF"/>
    <dbReference type="OrthoDB" id="1782047at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00428">
        <property type="entry name" value="NqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011292">
        <property type="entry name" value="NqrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30586:SF1">
        <property type="entry name" value="PTHR30586:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01939">
        <property type="entry name" value="nqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0915">Sodium</keyword>
    <keyword evidence="13 14" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <keyword evidence="11 14 15" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA87670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="22479" checksum="5FACECED7AE13843" modified="2008-04-29" version="1">MSTHTLSTRDILTNPVFTNNPVAMQVLGVCSALAVSNSLQTALVMTLAVTFVLVFSNLIISSIRRLIPNSVRIIAQMTVIASLVIIVDMVLQDVAYELSRQLSVFVGLIITNCIIMGRAEAFAMKNPPHLAVVDAFGNAIGYGVILLGVAFVRELLGSGTLFGHEVLQTVENGGWYLANEMFKLPPSAFFLIGLMIWSINVIQRKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT7</accession>
    <name>B1KQT7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3425"/>
    <dbReference type="EnsemblBacteria" id="ACA87693">
        <property type="protein sequence ID" value="ACA87693"/>
        <property type="gene ID" value="Swoo_3425"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3425"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1106525_0_0_6"/>
    <dbReference type="OMA" id="RWKDDKG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021856">
        <property type="entry name" value="DUF3465"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11948">
        <property type="entry name" value="DUF3465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="CSP" evidence="3">
        <location>
            <begin position="7"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="276" mass="30589" checksum="01AF314D7698BFC0" modified="2008-04-29" version="1">MQKSNIKGTLVRWKDDKGFGFIQAEPELDRDVFIHASTLSHMSRRPKEGDIIYFQLERKSDGKFNAVEAYIDGVECKSEEDTNSKAKKGLRSQQRDTINSRKSANQSQGQTRGILYRIGIMMLVLAGASFAYNRVVGSSGVANDSFELSQSSIIAADNTPSSISNTGVNAISKAYQNRLNGVQVSSSGTVVKLLDDDNEGSRHQRFILCLSNEQTLLVAHNIDLSPRIETLALGDIVEFNGQYEFNSKGGVIHWTHDDPQGKHVSGWLKHNGQIYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR11</accession>
    <name>B1KR11_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323176.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0531"/>
    <dbReference type="EnsemblBacteria" id="ACA84828">
        <property type="protein sequence ID" value="ACA84828"/>
        <property type="gene ID" value="Swoo_0531"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0531"/>
    <dbReference type="eggNOG" id="ENOG5032YVH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179405_1_0_6"/>
    <dbReference type="OMA" id="MMKDIIW"/>
    <dbReference type="OrthoDB" id="1844907at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019629">
        <property type="entry name" value="Uncharacterised_HI1736/YgjV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10688">
        <property type="entry name" value="Imp-YgjV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="82" mass="9160" checksum="271D466C488B6542" modified="2008-04-29" version="1">MDTANTIEIIGYSASVMVAISLMMKDIIWLRCLNFTGCTLFVIYGVYISAWPVAGMNAFVACINIYHLIKLYREKSQQSATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH8</accession>
    <name>B1KRH8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine synthetase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324730.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2101"/>
    <dbReference type="EnsemblBacteria" id="ACA86385">
        <property type="protein sequence ID" value="ACA86385"/>
        <property type="gene ID" value="Swoo_2101"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2101"/>
    <dbReference type="eggNOG" id="COG0174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_0_1_6"/>
    <dbReference type="OMA" id="GFAFCDV"/>
    <dbReference type="OrthoDB" id="416474at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="2">
        <location>
            <begin position="115"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="51086" checksum="B7FBDD0DAB5DF265" modified="2008-04-29" version="1">MEAREVKSIADAIAIIDERELTHVKVGVFDNDGVMRGKYMSKAKFIASLEKGFAFCDVVLGWDVKDQLYDNAKYTGWHTGYPDAPVRILPHTCRDVIGEEGMLLFIAEFAEEAEAVCPRGTLRRVIEKADSMGFNAFAALEYEFFLFNETPHSIRKKNFRDLETITPDWFGYSMIRNSAHSDLYQDILSMAETMDFPIEGIHSETGPGVIEAAIAVDSAETAADKGALFKTFMKVLAQKRDLMATFMAKWSGDYPGQSGHIHLSLQNKDGTSAFYDPSQTHSMSKIQRHFLAGQQKLMPEFLCMIAPTINSYSRMIPGFWAPTDATWGVENRTTALRVIPGSAKSQRVEYRLGAADANPYLALAAALASGLYGIEHELEPEAQVKGNAYEQTHDVQLALPATLWDAAQKFKQSTAAVSCFGEAFVEHYAISREWEEREFRKHVTDWEMARYFEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH9</accession>
    <name>B1KRH9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324731.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2102"/>
    <dbReference type="EnsemblBacteria" id="ACA86386">
        <property type="protein sequence ID" value="ACA86386"/>
        <property type="gene ID" value="Swoo_2102"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2102"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_6"/>
    <dbReference type="OMA" id="FAMTEMT"/>
    <dbReference type="OrthoDB" id="293754at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="9"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="471" mass="51667" checksum="A63D5B6455C424A1" modified="2008-04-29" version="1">MELPSQEMMQDTVSPIDGSVFVSRPLADEQQVLACVEQGTLAYKGPENSWKETKLCERKDLCKKAIEQLLSHKDEIASELSWMMGRPIRYGAGELAGVAERSDYMIEVCEKALADITLEERSGFTRYIKRESLGVVLVIAPWNYPFLTAINAIIPALLAGNCVILKHSAQTPLCAERLYQAFTDAGLPQGVFQYLHMDHDNTAKLIANEQINYVAFTGSVFGGEMVEKAAVGRFIGVGLELGGKDPAYVREDADIDSAVETLVDGAFFNSGQSCCGIERIYLHHSIYDEFVAKAVALTEQYQLGRSDESNTTLGPLVRTSAADFVRQQIDDAVAQGAIAHIDESLFPMSQSGTPYLAPQILTQVDHTMKVMTQESFGPVVGIMKVMDDDEAVALMNDSDFGLTASIFTQDIDLGITLGEQLQTGTFFLNRCDYLDPALAWTGVKQSGRGCTLSQLGFDQLTRPKSFHIKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRJ2</accession>
    <name>B1KRJ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326091.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3492"/>
    <dbReference type="EnsemblBacteria" id="ACA87757">
        <property type="protein sequence ID" value="ACA87757"/>
        <property type="gene ID" value="Swoo_3492"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3492"/>
    <dbReference type="HOGENOM" id="CLU_200566_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="74" mass="8181" checksum="035C313A904390B7" modified="2008-04-29" version="1">MTREEGIEALAIITEGSISNSVVRKRILDELSELKSIRGHFPAKGILADIQAHSDLKISEETGLLIKEVCFNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRP4</accession>
    <name>B1KRP4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Smp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326142.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87809">
        <property type="protein sequence ID" value="ACA87809"/>
        <property type="gene ID" value="Swoo_3545"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3545"/>
    <dbReference type="eggNOG" id="COG3726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088579_0_0_6"/>
    <dbReference type="OMA" id="QMMLIIA"/>
    <dbReference type="OrthoDB" id="1664449at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019305">
        <property type="entry name" value="Uncharacterised_Smp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10144">
        <property type="entry name" value="SMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="221" mass="25172" checksum="BE1EFA1160F988E6" modified="2008-04-29" version="1">MFFLKGLKKSHRISRFIQITIALTLAVGLIQLWETSLLQGQQLLKSQTEKMARLMVQQTAYGAAPALQLENDEQLQWLATALVLDPKVMSASIFSEDGQRLSFAQSVSTEELEPESEELQALLAPYPPYVEAVSQDGNNLGFIEVRLEPRLFFNEIKEAHQINMKQQQMMLIIAGLIGMLLSRALSFKRADFDRRKTRFKFRKKPSKLKKETLPEEVASSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRQ2</accession>
    <name>B1KRQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3553</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3553"/>
    <dbReference type="EnsemblBacteria" id="ACA87817">
        <property type="protein sequence ID" value="ACA87817"/>
        <property type="gene ID" value="Swoo_3553"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3553"/>
    <dbReference type="eggNOG" id="ENOG5031H5I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_211074_0_0_6"/>
    <dbReference type="OMA" id="IAWCDEM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="53" mass="6141" checksum="26FCA449B8BBE794" modified="2008-04-29" version="1">MNWIVKVWRGYIAWCDEMGLTPENRRCCAPRLEEPELVSTKPVSKTCEPSKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD30</accession>
    <name>B1KD30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87865">
        <property type="protein sequence ID" value="ACA87865"/>
        <property type="gene ID" value="Swoo_3601"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3601"/>
    <dbReference type="eggNOG" id="ENOG5031H5M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3391276_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="32" mass="3749" checksum="2179A2AD064677E0" modified="2008-04-29" version="1">MSYTGIQHVYWQNTWFCTDSLRGGLYAMSFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD32</accession>
    <name>B1KD32_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminoacyl-histidine dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3603"/>
    <dbReference type="MEROPS" id="M20.007"/>
    <dbReference type="EnsemblBacteria" id="ACA87867">
        <property type="protein sequence ID" value="ACA87867"/>
        <property type="gene ID" value="Swoo_3603"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3603"/>
    <dbReference type="eggNOG" id="COG2195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028526_0_0_6"/>
    <dbReference type="OMA" id="KGGYPGW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03890">
        <property type="entry name" value="M20_pepD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001160">
        <property type="entry name" value="Peptidase_M20C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43501">
        <property type="entry name" value="PTHR43501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016599">
        <property type="entry name" value="Xaa-His_dipept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00934">
        <property type="entry name" value="XHISDIPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01893">
        <property type="entry name" value="aa-his-dipept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="220"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="497" mass="53989" checksum="CE901AA4F7C4B8AA" modified="2008-04-29" version="1">MGLHIIKGELSVTAINQLQPQALWQWFDQICAIPHPSKHEQALSAHIQAWAKDKQLDIVEDKVGNLIIKKPATPGMENRKVVALQAHIDMVPQKNADKEHDFEKDPIIPFVDGEWVKATGTTLGADNGIGMASALAVLGSDDIPHGPLEVLLTIDEEAGMTGAFGLEAGYLDAEILINTDSEQEGEIYMGCAGGVDAQISVPMVWQSPEQSNATYTLTLSGLKGGHSGVNIHLGRGNANKLLARFLFNHADELALELTNFSGGSLRNAIPREASVSFMLPAENVSKLEELTQTFQALVREELAIADPGMLFELAEVPAATQVMSEDAQNTLIDLLNACPNGVIRMSDEVEGVTETSLNVGVISTETESVEVLCLIRSLIDSGRQDVETVLTSLTNLAGAEIEFSGAYPGWKPDNSSPVMALVRETYDSIYNKEPVIMVIHAGLECGLFKKPYPEMDMVSIGPTIRYPHSPDEKVLIETVEQYYKLLLAVLERIPEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDB7</accession>
    <name>B1KDB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-succinylhomoserine (Thiol)-lyase</fullName>
            <ecNumber evidence="4">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323265.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0622"/>
    <dbReference type="EnsemblBacteria" id="ACA84918">
        <property type="protein sequence ID" value="ACA84918"/>
        <property type="gene ID" value="Swoo_0622"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0622"/>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_0_6"/>
    <dbReference type="OMA" id="YKQDGVG"/>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011821">
        <property type="entry name" value="O_succ_thio_ly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02080">
        <property type="entry name" value="O_succ_thio_ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="41290" checksum="6FA3E04FEBAB02C0" modified="2008-04-29" version="1">MTERKLATIAVRQGIESDTQHGAVVPPIYLSTNYSFDGHKNPRDFDYSRSGNPTRSILGDAIAGLEKGATGVVTCTGMAAITLVTSLLGPDDLLVVPHDCYGGSYRLFTNLAKKGQFKLAVVDQTDSQALSEAIALKPKMVWLETPSNPLLRVVDIEAIAQASHEVEALVVVDNTFLSPILQQPLLLGADIVIHSTTKYINGHSDVVGGAVVAKDPELGELLHWWSNTLGLTGSAFDSYLALRGLRTLPIRIKEHQANAERVLEVLTNSSAVDKVYYPGLKDHPGHEIAAKQQKGFGAMLSFELKGGEAELVAFLAQLSVFSVAESLGGVESLVAVPATMTHRAMEPEARAEAGVKETLIRLSVGIEDADDLVADIQAGLTAASAASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG2</accession>
    <name>B1KDG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heavy metal efflux pump, CzcA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0667</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323310.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0667"/>
    <dbReference type="EnsemblBacteria" id="ACA84963">
        <property type="protein sequence ID" value="ACA84963"/>
        <property type="gene ID" value="Swoo_0667"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0667"/>
    <dbReference type="eggNOG" id="COG3696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="QVMMLKG"/>
    <dbReference type="OrthoDB" id="91817at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="527"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="905"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="930"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="976"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1008"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1042" mass="113443" checksum="9773F745C6E00D8B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDI9</accession>
    <name>B1KDI9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323337.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84990">
        <property type="protein sequence ID" value="ACA84990"/>
        <property type="gene ID" value="Swoo_0695"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0695"/>
    <dbReference type="eggNOG" id="ENOG50335HB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148043_0_0_6"/>
    <dbReference type="OrthoDB" id="1951145at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766972" evidence="1">
        <location>
            <begin position="28"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="16986" checksum="1B6827B45C1FF1F6" modified="2008-04-29" version="1" precursor="true">MTRQLTMTFAFLFTSLCMLFSSGVANADDTKKIITESSAQVKDAQATNGQVKLIAGQERAWQASQAQWLSLDAFWQYWADSRGGITWGSSRDYPPYDQVKEQDTLLIQLDSGTCMMEFWHSRWRRANDVRRWDDAFNHYSACPYVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ4</accession>
    <name>B1KDJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323342.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0700"/>
    <dbReference type="EnsemblBacteria" id="ACA84995">
        <property type="protein sequence ID" value="ACA84995"/>
        <property type="gene ID" value="Swoo_0700"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0700"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_12_2_6"/>
    <dbReference type="OMA" id="VRKCFIL"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="13"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="114"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="23080" checksum="61A19FB7E8C09DD6" modified="2008-04-29" version="1">MVAKNKSNVSDIFAKYSNKLKRVIGRIVQPDDIDDIVQDTFVRSYEAELKQEIKYVRSYMLKTAKHLALNHVAKSSYRFNHSIEEFVETPIELISTSFESEFESKERFLFFCRATEQLSEPVRKCFILKKVYGLSQSEIAKYLNISESTVEKHVAKGLFKSVQYMESVSAQGESLQTPSALSKRSAGHQDSQSNIKEFISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ5</accession>
    <name>B1KDJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-FecI sigma factor, FecR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323343.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0701"/>
    <dbReference type="EnsemblBacteria" id="ACA84996">
        <property type="protein sequence ID" value="ACA84996"/>
        <property type="gene ID" value="Swoo_0701"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0701"/>
    <dbReference type="eggNOG" id="COG3712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050192_0_2_6"/>
    <dbReference type="OMA" id="IMVTSGH"/>
    <dbReference type="OrthoDB" id="1381035at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018266">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="120"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="39630" checksum="E19C703CB380B2D4" modified="2008-04-29" version="1">MSTIKQFYSKEELQEQAALWISRIDRGLSEVEIDSLSKWVSESKAHQDALFEMASYWDDLSVLNELSVLFPLETAKNKSKWQYAAIAASFLLLSFVGGNWLLGGQISQHIWGAGEIYTQRLESPVGKQTSFSLPDGTQVQLNTNSVVEVDYSSNYRQLTLVTGEAKFDVAKDRSKPFTVTAGVQAFTALGTVFNVQKNDEQDMELVVTHGKVLVTSVDKSLEQIKESLSDIAEQSLPGLLVSTGEKVVIAKNTSLAVEALPLEQMQRDLAWQQGMLIFEGEPLSQALDDVSRYTSVKFEIVDPELSELKVAGYFKAGDVDGLLASLSSNFNIVHVKDSDNIIHLTAPSNTNPTKKLTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL3</accession>
    <name>B1KDL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324755.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2126"/>
    <dbReference type="EnsemblBacteria" id="ACA86410">
        <property type="protein sequence ID" value="ACA86410"/>
        <property type="gene ID" value="Swoo_2126"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2126"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_5_6"/>
    <dbReference type="OMA" id="MLKHQIP"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="206"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="341" mass="38527" checksum="5FEEF82EDA512B3D" modified="2008-04-29" version="1">MSKELMQVAALNLKKAVPLMLKHQIPTTPTNYALWYAYVGEQQPQLNEQLDTIINEHSTCPPSNSTLLYREFVADPVELDVIDMRQNLEAMATELSQSLKDTNTDATHFQKRIDSNFDKLNRIEEEGVSLEKVLGVVRNLVKESDEIRSSTEYFTGHLKRAQQEIDALKAQLKKSEKDVLFDALTGVLNRRAFDSDLKGSLSQSPDGLCLILIDIDHFKAFNDNYGHQLGDQVLKAVAKRLGESCREGTKLYRYGGEEFAVITANSQLRKARHLAEAMRRALEKVSLKDRRKDAMINNITASFGVAQWDPSLSATQLIEQSDKLLYEAKRLGRNRVMPIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL8</accession>
    <name>B1KDL8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative GAF sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324760.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2131"/>
    <dbReference type="EnsemblBacteria" id="ACA86415">
        <property type="protein sequence ID" value="ACA86415"/>
        <property type="gene ID" value="Swoo_2131"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2131"/>
    <dbReference type="eggNOG" id="COG1956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077738_2_0_6"/>
    <dbReference type="OMA" id="DNYIACS"/>
    <dbReference type="OrthoDB" id="1739746at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000614">
        <property type="entry name" value="FRMsr_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01320">
        <property type="entry name" value="UPF0067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="36"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="152" mass="16582" checksum="74E07E09F971A131" modified="2008-04-29" version="1">MDLECYDSLNRQAQALLSGEDDLVAAMANFSALINDAVEQLNWVGFYLLKDEQLVLGPFQGKVACSRIPLGKGVCGTSAAEKKTMRVDDVHQFDGHIACDSASNSEIVIPVFDNNRLIGVLDIDSPILNRFTKTDQIGLENLVKSFESALFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDP9</accession>
    <name>B1KDP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uracil-xanthine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324790.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2162"/>
    <dbReference type="EnsemblBacteria" id="ACA86446">
        <property type="protein sequence ID" value="ACA86446"/>
        <property type="gene ID" value="Swoo_2162"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2162"/>
    <dbReference type="eggNOG" id="COG2233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017959_1_2_6"/>
    <dbReference type="OMA" id="INHGIGM"/>
    <dbReference type="OrthoDB" id="1115239at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01116">
        <property type="entry name" value="XANTH_URACIL_PERMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="415" mass="42967" checksum="4F2D0C7B31B42056" modified="2008-04-29" version="1">MKNVSLALQGAQMLFVAFGALVLMPLLTGLDTNVALFTAGIGTLIFQLITKRQIPIFLASSFAFIAPIMYGVQTWGIPSTMGGLMAAGCVYLILASLVKVRGDGFIKRLLPPVVVGPVIIVIGLGLAPVAVNMALGKSGDGSLVLVEQSTALIISLSALLSTVAVAIFAKGLLKLMPILAGILVGYGLSLTFGIVDFTPVIAASWIAMPNFVAPEFNWHAIAFMIPVAIAPAVEHIGDILAISNVTGKDYLKKPGLHRTLAGDGVATIAASAFGGPPNTTYSEVTGAVTLTKNFNPVIMTWTAITAIVLAFVGKLGAIMQTIPVPVMGGIMCLLFGSIAAVGLNSLIKNQVDLTEPRNLCIVGITLVFGIGGMAFGIGSFSLTGISLCGIVAITMNLLLPMPKTSNSEEIETSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDW1</accession>
    <name>B1KDW1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LPS-assembly lipoprotein LptE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lptE</name>
        <name evidence="3" type="ordered locus">Swoo_3703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LptE lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326295.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3703"/>
    <dbReference type="EnsemblBacteria" id="ACA87963">
        <property type="protein sequence ID" value="ACA87963"/>
        <property type="gene ID" value="Swoo_3703"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3703"/>
    <dbReference type="eggNOG" id="COG2980">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103309_1_0_6"/>
    <dbReference type="OMA" id="TTVNRNY"/>
    <dbReference type="OrthoDB" id="1685955at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01186">
        <property type="entry name" value="LPS_assembly_LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007485">
        <property type="entry name" value="LPS_assembly_LptE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38098">
        <property type="entry name" value="PTHR38098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04390">
        <property type="entry name" value="LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="18825" checksum="C7F50B80B58B3EBD" modified="2008-04-29" version="1" precursor="true">MLIKRICFAIMTLAILFSAGCGFKLQGSYSIPEQLRTLHLSSQDQYSELTRLVRERLRLHSITLAEDSDNVPTLQILHDSLDRSTLSLYPTGNVAEYELTYHVTFAVAFPDKESQRFDVDIHRDYLDDPRTALAKSREMEMLLKEMRIQAADQMIQTLASIEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDY3</accession>
    <name>B1KDY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326317.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3725"/>
    <dbReference type="EnsemblBacteria" id="ACA87985">
        <property type="protein sequence ID" value="ACA87985"/>
        <property type="gene ID" value="Swoo_3725"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3725"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="SDIDQCN"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032255">
        <property type="entry name" value="HBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01358">
        <property type="entry name" value="HBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="290"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="348"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="620" mass="67923" checksum="03CEEC8401B7E605" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE53</accession>
    <name>B1KE53_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323386.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0744"/>
    <dbReference type="EnsemblBacteria" id="ACA85039">
        <property type="protein sequence ID" value="ACA85039"/>
        <property type="gene ID" value="Swoo_0744"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0744"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128126_0_0_6"/>
    <dbReference type="OMA" id="NQKAWYN"/>
    <dbReference type="OrthoDB" id="2033955at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767283" evidence="2">
        <location>
            <begin position="24"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="18295" checksum="65698A33044E261C" modified="2008-04-29" version="1" precursor="true">MARLIFKALLILSLMHLFGCASSTQEKEPKGNQQIMVLQSEAEQAYKMARLDQAESLYLQVLTSVPNYAPGWFRLGNIYTRTGRQDAAVSAYMRCLELDPSNQKAWYNMSLVRIKQSTQVLSSASRQGNPNTPVGRQIKALLHALNSIQSESHAPVLPSEQASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB6</accession>
    <name>B1KEB6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fmu (Sun) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324838.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2212"/>
    <dbReference type="EnsemblBacteria" id="ACA86494">
        <property type="protein sequence ID" value="ACA86494"/>
        <property type="gene ID" value="Swoo_2212"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2212"/>
    <dbReference type="eggNOG" id="COG0144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_0_2_6"/>
    <dbReference type="OMA" id="GWFEQQD"/>
    <dbReference type="OrthoDB" id="1064993at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="5">
        <location>
            <begin position="143"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="45292" checksum="E4768D215007B31F" modified="2008-04-29" version="1">MLNSPLSPSSTELVISILDMVLSEGKPLDRAYSVHFSGLQLIPSEQARITKVVGDILRRLNLYCFLSDVKPEEISRLGSRLMNAWHLFHELELPKLQYSLPLAEAEYFARLEEAKLQPALWDGCPEWLDTMGQAQLGEAWAKERAALNTQPKRFIRTNILKCTREELAKKLRNEQVQTTEVDGVDTALEVVSDSALFRTESFKKGWFEQQDAGSQLVAAAVDAKPGMRVIDACAGAGGKTLSIAAQMKGKGRLLAMDVEQWKLDNLKQRARRANASNVETRIIASSKTIKRLKLSADRLLLDVPCSGLGVLKRNPDAKWRDTPDRLPVLVELQKHILQSYSRMVKVGGILIYATCSIMPEENRDQVDAFLAENEHFTFLEDETISVADSGFDGFYMARLERIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE1</accession>
    <name>B1KEE1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TM2 domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324862.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2238"/>
    <dbReference type="EnsemblBacteria" id="ACA86519">
        <property type="protein sequence ID" value="ACA86519"/>
        <property type="gene ID" value="Swoo_2238"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2238"/>
    <dbReference type="eggNOG" id="COG2314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2314053_0_0_6"/>
    <dbReference type="OrthoDB" id="2047618at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="6">
        <location>
            <begin position="5"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="101" mass="11339" checksum="115A6F7F01046DCC" modified="2008-04-29" version="1">MEVKNKSRLIALLLTFPPFGLLGLDRFYLGFIGLGILKAITLGGLGIWWFFDGAVLLLDAFAYSLGKDTGFRKDSRGNDLKHGLSMFRRKNGEWVKDWGAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEK5</accession>
    <name>PYRC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydroorotase</fullName>
            <shortName evidence="1">DHOase</shortName>
            <ecNumber evidence="1">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrC</name>
        <name type="ordered locus">Swoo_3761</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-dihydroorotate + H2O = H(+) + N-carbamoyl-L-aspartate</text>
            <dbReference type="Rhea" id="RHEA:24296"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="EC" id="3.5.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326352.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KEK5"/>
    <dbReference type="SMR" id="B1KEK5"/>
    <dbReference type="STRING" id="392500.Swoo_3761"/>
    <dbReference type="EnsemblBacteria" id="ACA88020">
        <property type="protein sequence ID" value="ACA88020"/>
        <property type="gene ID" value="Swoo_3761"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3761"/>
    <dbReference type="eggNOG" id="COG0418">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041558_1_0_6"/>
    <dbReference type="OMA" id="TLHHISM"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01294">
        <property type="entry name" value="DHOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="PTHR43137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000100063" description="Dihydroorotase">
        <location>
            <begin position="1"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00219"/>
        </source>
    </evidence>
    <sequence length="344" mass="37682" checksum="1C4274D16A6FC023" modified="2008-04-29" version="1">MTQITLLTPDDWHLHFRDGDMLQETVPATARLFQRAIVMPNLLPPVTDAKLASAYRERILAARPEGSSFEPLMTIFLTNDTSKQDIIDAKAAGVVAAKLYPAGATTNSDAAVKGLDALFPIFETMAEIGMLLLVHGEVTESHIDIFDREALFIERNLSRIVDAFPQLKVVFEHITTKEAAEFVTSASDNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRNIHQEALRAAVATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGVIEKLEGFASTHGPDFYGLPRNTGTVTLVKESWTVPSEIILPNGNPIVPFFAGEEVNWKVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF59</accession>
    <name>B1KF59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324942.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2321"/>
    <dbReference type="EnsemblBacteria" id="ACA86600">
        <property type="protein sequence ID" value="ACA86600"/>
        <property type="gene ID" value="Swoo_2321"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2321"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047522_1_3_6"/>
    <dbReference type="OMA" id="QNTEFTG"/>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="236"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="39761" checksum="1B1D5BDCA6D49E4B" modified="2008-04-29" version="1">MADYYSTLSGWIIPFSRAMDACDIDVDKAFSVCGIDASAVKDPEARIGTQRFVELLDYCNDLREVNDFSIQVGQYFHPGMFHALGYAMMTSNTLKDALARIVTYKRVVSNACTLDLDETQEHLVLKMMVSTFETTGRKVLSREATETFLAIVVQFTRELLGVNFHPKRVIIGYEQPQHGTKYLNQFFECDVEFGDGDSYLYFEKVHAEEYLCVANPMINGIHEKMLTDFLSRIDRHDLTYVIKNKIYEILPLGAPSQQEIADKLGMSLRNLQRKLQEQDTCYKTILEDTRKSLTLDYIKQAHLSLSEIGYLVGFSSVGNFNRAFKRWTNLTPGEYRRGYISDGNIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC0</accession>
    <name>B1KFC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2382</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325003.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2382"/>
    <dbReference type="EnsemblBacteria" id="ACA86661">
        <property type="protein sequence ID" value="ACA86661"/>
        <property type="gene ID" value="Swoo_2382"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2382"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047407_5_0_6"/>
    <dbReference type="OMA" id="HSLRSGC"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="7">
        <location>
            <begin position="25"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="6">
        <location>
            <begin position="150"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="40966" checksum="275CE8306010CCF4" modified="2008-04-29" version="1">MNKMTPFQTGSLLSRPANTEEKQFYEERELPLSILDDYKSAASETEYEISANTRRAYTSSFSLFSNYCSEHRLNTLPADPRTVISFIGYQKELIQSRSGAQLSRQTLTSRLAAIRYFHIQAGYHSPTEHPLVIRVMRGLSRNKQRTVSDYDQQPIMYDELEMLLNVIELQPHAITRARDKAIIQLGFQGGFRRSELADIRVNHLSFLRDKLKVRLPYSKSNQQGQREWKNLPQSEPFAAFDAVKHWLTVSKIQDGHLFRSLTRDGRQVRDYSVATQGIESKKRNSGFLRGDDIYQMIRKYCTKAGLSHEFYGAHSLRSGCVTQLHENDKDHLYIMARTGHTDPRSLKHYLKPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE5</accession>
    <name>B1KFE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4-aminobutyrate aminotransferase</fullName>
            <ecNumber evidence="5">2.6.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3862</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326450.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3862"/>
    <dbReference type="EnsemblBacteria" id="ACA88120">
        <property type="protein sequence ID" value="ACA88120"/>
        <property type="gene ID" value="Swoo_3862"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3862"/>
    <dbReference type="eggNOG" id="COG0160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_0_6"/>
    <dbReference type="OMA" id="GMTTQIY"/>
    <dbReference type="OrthoDB" id="1322538at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047298">
        <property type="term" value="F:(S)-3-amino-2-methylpropionate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003867">
        <property type="term" value="F:4-aminobutyrate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009448">
        <property type="term" value="P:gamma-aminobutyric acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004632">
        <property type="entry name" value="4NH2But_aminotransferase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00700">
        <property type="entry name" value="GABAtrnsam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="427" mass="45410" checksum="E4C79E95D91BD206" modified="2008-04-29" version="1">MTNSSLQARKVKAIARGQGNAYPVYVERAKNAELWDVEGKRYIDFGTGIAVCNTGHSHPKIVAAVKAQLDNFSHTCVMVNPYESAVELAEKLTEIAPGESDKKAIFVTTGAEAVENCVKIARAHTGRRGVIAFNGGFHGRTNLTMALTGKITPYKHQFGPFAGDVFHAPFPIDYHNISVKHSLDALNNLFKVDIAPCDVAAIIVEPVQGEGGFYAAPAEFLQALRSLCDDHGIVLIADEIQTGFGRTGKMFSFEHAGVEPDLITMAKGIAGGFPIAAVVGKSEIMDAPLPGGLGGTYGGSPVACVAALTVLDVIKEEGLVERAAQIGAIFNERLTALQAEYPQLIGEVRNQGAMIAMELVSNGDCEQANTALTQAIIAKAAKYGLILLACGFYGNVIRFLPALTISDELINEGLDQFVRLFGEAANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE7</accession>
    <name>B1KFE7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326452.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3864"/>
    <dbReference type="EnsemblBacteria" id="ACA88122">
        <property type="protein sequence ID" value="ACA88122"/>
        <property type="gene ID" value="Swoo_3864"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3864"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_0_0_6"/>
    <dbReference type="OMA" id="ERQVAYC"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="34846" checksum="9C02C2745440A0F2" modified="2008-04-29" version="1">MKKHSIIPKAITEYDLRLLRIFRTVVENGGFAASETELGVTRSTISVHMSNLESRMKLKLCSRGRGGFALTEDGQAVYHACIELFDSLNDFSMLVSSLGEELSGELTLLCADQLDNTMQKKLAEVIRYLHQKEPQLHLILDGDSIHNIERALLQDKAHLGLLPSYHQIEGLNYHTIYSEPIYLCCSEHHPYFELEDGEITPEMLAQSPSIHPGIDIDSDGREQLKKLNLSAKAYQFDTRKTLILSGCYIGYLPESYIQNELTTKQMRIIHSDSARYQFNLSMVFKKNPRETHKVELLKTAFHKVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFH6</accession>
    <name>B1KFH6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TraR/DksA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3893</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88151">
        <property type="protein sequence ID" value="ACA88151"/>
        <property type="gene ID" value="Swoo_3893"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3893"/>
    <dbReference type="eggNOG" id="COG1734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043144_3_3_6"/>
    <dbReference type="OMA" id="ECGESIG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="6">
        <location>
            <begin position="62"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14706" checksum="78F2381447944846" modified="2008-04-29" version="1">MRVTHPNLRQNALKQAPLSSDERAQLLTKLKQELNELEQQLELAHSRGAPVILDQQAVGRVSRIDAIQQQEMAQASEVLMQQHIVRIKQIFLDTDEYGFCLECGEPIGLGRLTIHPTAEMCIGCQSEAENC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFH8</accession>
    <name>B1KFH8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326483.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88153">
        <property type="protein sequence ID" value="ACA88153"/>
        <property type="gene ID" value="Swoo_3895"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3895"/>
    <dbReference type="HOGENOM" id="CLU_1554230_0_0_6"/>
    <dbReference type="OMA" id="GVHATER"/>
    <dbReference type="OrthoDB" id="2129356at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767019" evidence="1">
        <location>
            <begin position="19"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="172" mass="19544" checksum="634A2EFB29D6AF0F" modified="2008-04-29" version="1" precursor="true">MRFIVICIALIVTFGAHASDFDKIVKNYTAAVNSNDFELVAELLHPNELDLLKEKVDGSLQSSNKSSADKGLLRLLGVDSRQQAFKLTPKDVYIRICNNLMARYPNEALEIAIASSIYLGEERHDDIVVVTYKMTYNTGDEPVTRIVQHRLKEYKDSWRFLLTPETLAYFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK3</accession>
    <name>B1KFK3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3920"/>
    <dbReference type="EnsemblBacteria" id="ACA88178">
        <property type="protein sequence ID" value="ACA88178"/>
        <property type="gene ID" value="Swoo_3920"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3920"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_6"/>
    <dbReference type="OMA" id="EFNILHF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="26615" checksum="7D130840BBAF6C00" modified="2008-04-29" version="1" precursor="true">MMSTMDPIKILVIEDDKLLNAQLAELLRAKGYLVNQSFDGEDGLLQASSKLYQLILLDVMLPGRDGFSLLKMLRKSCQTPVIMVTAKGAEEERIQGFSQGADDYVAKPFSSTELLLRIEALLRRSHTLKNELISHELILDSLQINYREQTVMVCEQVLEFTPIQFKLLWELLLHRGEVLSKAYLYQKVLNRNIGAYDRSLDMHLSRVRRKLNDADWQGERLQTCHGKGYCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM1</accession>
    <name>B1KFM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3939</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3939"/>
    <dbReference type="EnsemblBacteria" id="ACA88196">
        <property type="protein sequence ID" value="ACA88196"/>
        <property type="gene ID" value="Swoo_3939"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3939"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="NISNRWD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767318" evidence="5">
        <location>
            <begin position="44"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="73"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="483"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1017" mass="111147" checksum="AE8D89231D00BC20" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT0</accession>
    <name>B1KFT0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0953</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leucine-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323593.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0953"/>
    <dbReference type="EnsemblBacteria" id="ACA85246">
        <property type="protein sequence ID" value="ACA85246"/>
        <property type="gene ID" value="Swoo_0953"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0953"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_7_1_6"/>
    <dbReference type="OMA" id="FVEMTII"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000709">
        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00337">
        <property type="entry name" value="LEUILEVALBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="3">
        <location>
            <begin position="58"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="426" mass="46197" checksum="B0069E55CE5E7814" modified="2008-04-29" version="1" precursor="true">MLKATRFSGRHYLTRWTSVAHRLFNPSSLLFFSLFLSTFIATGVWAQASEVESSQEEILLGMSTALSGPAEQLGKNMLLGVNMQFAKENSQGGINGRQLRLIAMDDGYEPNRTAPNMRTLIEQDKVLAVIGNVGTPTAISAIPIANEKQTLLFAPFTGAGVLRKTPPDRYIINYRASYAEETSTMVDALIKHAGLKPEEIAFFTQRDGYGDAGYIGGITALLKNGLKSKSQVVHGRYERNTLSVDNALADIILAEVTPKAIIMVGAYAPCARFIKLARESGVNALFLNVSFVGSAPLAKQLGESVKGVVVTQVVPHPENLSLPVVKEYQDALTAFAPDALPSFGSLEGYIAAKIMTKALKTISGKPTRESLIDALEALGKFDAGVGNSLYFDANSHQASHMVWPTRLEKGKFVSFEWSDIASFIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT4</accession>
    <name>B1KFT4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="2">PPIase</shortName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323597.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0957"/>
    <dbReference type="EnsemblBacteria" id="ACA85250">
        <property type="protein sequence ID" value="ACA85250"/>
        <property type="gene ID" value="Swoo_0957"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0957"/>
    <dbReference type="eggNOG" id="COG0652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_9_6"/>
    <dbReference type="OMA" id="LQADICY"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006522157" description="Peptidyl-prolyl cis-trans isomerase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="47"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="215" mass="22795" checksum="99C4C0BC1DBAD67D" modified="2008-04-29" version="1" precursor="true">MKKLILSLVFGSTLVACGGGSDSGDTSVPPSPEPAPELAADVCYLMDTSMGEVKLAIDLTNTPVTGNNFKQYVDEGFYDGVIFHRVITQFMAQTGGFTPGLIYKEGRDPITNESDVGISNARGTLAMARTSAPNSATSQFFINAVDNTFLDKEHAQDGVGYAVFGKVIEGLEDVIDQIDIVKTGVAKDPDGNSFSDVPVEDIVINSISETACPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFU2</accession>
    <name>B1KFU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323605.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0965"/>
    <dbReference type="EnsemblBacteria" id="ACA85258">
        <property type="protein sequence ID" value="ACA85258"/>
        <property type="gene ID" value="Swoo_0965"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0965"/>
    <dbReference type="eggNOG" id="COG3014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035715_0_0_6"/>
    <dbReference type="OMA" id="NDAFIDY"/>
    <dbReference type="OrthoDB" id="1203790at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767322" evidence="2">
        <location>
            <begin position="21"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="200"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="49998" checksum="BEFDD0F881034B4C" modified="2008-04-29" version="1" precursor="true">MKKWLLIPLLSLSLTGCAFNSIFINYPSQIAPVKAQINSNDPIKGADEVADNISGADGLLYAQEAGRVAQIAGDFEASKAYYQQAVAAYLEFDDKATLSASDLGATASSLFINDNVIPYRGPGYERVMLHQYQALNYLLSGDKEGALVEVRRSNNLQSSEQRRYQKSNESVQAIANGTIDAEVNKLGQAAGSVTSSFLNAYSYYITGVLHEILGEPNDAFIDYRKAAQIAPNNPYVQKDLVRLAKQLSMPQADEFEKRWGKAAKPKKGEGEVIILVERGFVDEKQSLTVPFRVHGSWQTASLATYPFNSRPVAKGQIKGLDKRLTAAPIANIDALAITALKEELPAALVRQAARAYAKAEMARSVRSESKARNNETDFGSIAMQIFNVVTEQADRRSWLTLPKQAQIARTYVNQGQYSVQLDNSSPASVEVKSGRTTLVWVIDTGNYTRFYSIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFZ0</accession>
    <name>B1KFZ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome oxidase maturation protein, cbb3-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325039.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2419"/>
    <dbReference type="EnsemblBacteria" id="ACA86697">
        <property type="protein sequence ID" value="ACA86697"/>
        <property type="gene ID" value="Swoo_2419"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2419"/>
    <dbReference type="eggNOG" id="COG3197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176840_1_0_6"/>
    <dbReference type="OMA" id="PAYRILM"/>
    <dbReference type="OrthoDB" id="2095758at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004714">
        <property type="entry name" value="Cyt_oxidase_maturation_cbb3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41532">
        <property type="entry name" value="PTHR41532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03597">
        <property type="entry name" value="FixS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00847">
        <property type="entry name" value="ccoS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="64" mass="7296" checksum="C5A911E027600CB2" modified="2008-04-29" version="1">MSIIYVLIPIAMLFVIIAIGIFFWAVKSEQFDDLDRQSVSILFDEDESTPTNNKKVDDKTETPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG16</accession>
    <name>B1KG16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325065.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2445"/>
    <dbReference type="EnsemblBacteria" id="ACA86723">
        <property type="protein sequence ID" value="ACA86723"/>
        <property type="gene ID" value="Swoo_2445"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2445"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012431_9_0_6"/>
    <dbReference type="OMA" id="CRGTFRN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017806">
        <property type="entry name" value="EgtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03440">
        <property type="entry name" value="egtB_TIGR03440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="200"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="427" mass="49827" checksum="C61EF2FFBF87AE8B" modified="2008-04-29" version="1">MLSTETKVFSEVTTLLDCYLCVRNDTTDICQPLTIEDHAVQPSAEVSPPKWHLGHTTWFFEELILVRFMPEYERWNEQYRVLFNSYYKSAGEHWIQGERGNLSRPTVDEVLAYRSYVDHHMRLFLSSECLQGKESDAEMASEVAEILEIGLHHEQQHQELLYMDIKYILGVNPITVTYDDTQLLKAVPATGELWTDFDEGVYQLGHSGSGFAYDNESPRHKTYIYPFAMAKHTVSNGEYLEFIEAQGYRIAKYWLSQGWDWVTENRIKHPLYWLQEDGVWYEFTLNGKHALDLNAPVTHISYFEADAFASWKGCRLPTEQEFEIYLQQSTAEYGLTKTACHPNDTSADVGQVWCWTRSQYSAYPGFKPYQGVLAEYNGKFMCNQFVLKGGCVATPPGHYRHTYRNFYQPHQRWMFSGIRLSKDIEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB8</accession>
    <name>B1KGB8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3998</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326584.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88255">
        <property type="protein sequence ID" value="ACA88255"/>
        <property type="gene ID" value="Swoo_3998"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3998"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_6_0_6"/>
    <dbReference type="OMA" id="TFAATWL"/>
    <dbReference type="OrthoDB" id="881796at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="28205" checksum="B053F40320522871" modified="2008-04-29" version="1" precursor="true">MFQIDVICSFLLLGALVGFAAGLFGIGGGGIMVPMLTAIFLNQGIAMNTVVPLALGTSMAAIIVTSLSNLRAHNAKKGILWPVVTNMLPGIFLGTFASTFIASKVDAFYLALFFALFMAYVSMKMLFSKTVKSDQRIPNTGNMFLAGSGIGAISALVSIGGGSLTVPYLAGRSIEIKKAIGTSAAIGLPISVAGTLGYLIHGWNSTSLINYAVGYIYLPAVLLISITSFLTVPYGVKLAYYLPVTILKKMFALLLILISLNMVISILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC3</accession>
    <name>B1KGC3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent heme/hemoglobin receptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4004"/>
    <dbReference type="EnsemblBacteria" id="ACA88260">
        <property type="protein sequence ID" value="ACA88260"/>
        <property type="gene ID" value="Swoo_4004"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4004"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_19_3_6"/>
    <dbReference type="OMA" id="RVNNQYA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011276">
        <property type="entry name" value="TonB_haem/Hb_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010949">
        <property type="entry name" value="TonB_Hb/transfer/lactofer_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01785">
        <property type="entry name" value="TonB-hemin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01786">
        <property type="entry name" value="TonB-hemlactrns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767334" evidence="5">
        <location>
            <begin position="24"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="47"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="265"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="681" mass="75404" checksum="59CAAE1EE2AD1FCF" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGP1</accession>
    <name>B1KGP1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="10" type="ordered locus">Swoo_1076</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323715.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1076"/>
    <dbReference type="MEROPS" id="M17.003"/>
    <dbReference type="EnsemblBacteria" id="ACA85369">
        <property type="protein sequence ID" value="ACA85369"/>
        <property type="gene ID" value="Swoo_1076"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1076"/>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013734_2_2_6"/>
    <dbReference type="OMA" id="MKNTGPR"/>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="349"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="502" mass="54769" checksum="519D3E07683775D9" modified="2008-04-29" version="1">MEFSVKSGSPEKQRSACIVVGVYEPRRLSGIAEQLDKISEGYISNLLRRGDLEGKPGQMLLLHHVPNVLSERVLLVGCGKERELDERQYKQIITKTIKTLNETGSMEAVCFLTELHVKSRDTYWKVREAVETTQNSLYSFDALKTSKDETRRPLRKLVFNVPTRRELTVGERAIDHGMAVSAGMQLCRDVANMPPNICNPAYLASQARQISETCEELTVTTVGEEQMAKLGMNSYLAVGRGSDNESVMTVMEYKGAVDSTEKPIVLVGKGLTFDSGGISLKPGEAMDEMKYDMGGAAGVIGAMKALCEMKLPINVIGILAGCENMPSSNAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFDPELVIDTATLTGACVIALGKHASGLFSGHNPLAHEMLNAGEQSGDRAWRMPLWDEYQEHLESPFADMTNLGGRAAGSITAACFLSRFTKKYNWAHLDVAGTAWNSGANKGSTGRPVPLLTQFLINRAGVEQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS4</accession>
    <name>B1KGS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type VI secretion protein IcmF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2516</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325134.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2516"/>
    <dbReference type="EnsemblBacteria" id="ACA86793">
        <property type="protein sequence ID" value="ACA86793"/>
        <property type="gene ID" value="Swoo_2516"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2516"/>
    <dbReference type="eggNOG" id="COG3523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003353_1_0_6"/>
    <dbReference type="OMA" id="FFGYGGT"/>
    <dbReference type="OrthoDB" id="393769at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009612">
        <property type="entry name" value="IcmF-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025743">
        <property type="entry name" value="IcmF-related_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010623">
        <property type="entry name" value="IcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017731">
        <property type="entry name" value="TssM1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06761">
        <property type="entry name" value="IcmF-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14331">
        <property type="entry name" value="IcmF-related_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06744">
        <property type="entry name" value="IcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03348">
        <property type="entry name" value="VI_IcmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF-related_N" evidence="4">
        <location>
            <begin position="202"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF-related" evidence="3">
        <location>
            <begin position="511"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF_C" evidence="2">
        <location>
            <begin position="1060"/>
            <end position="1166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1187" mass="135834" checksum="AE6B90F092891878" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU4</accession>
    <name>B1KGU4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-dehydro-3-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2536</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:17089"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325154.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2536"/>
    <dbReference type="EnsemblBacteria" id="ACA86813">
        <property type="protein sequence ID" value="ACA86813"/>
        <property type="gene ID" value="Swoo_2536"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2536"/>
    <dbReference type="eggNOG" id="COG0800">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077795_1_1_6"/>
    <dbReference type="OMA" id="FFPAEYC"/>
    <dbReference type="OrthoDB" id="1497385at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031337">
        <property type="entry name" value="KDPG/KHG_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00159">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="22324" checksum="7A9B127C383B9F0E" modified="2008-04-29" version="1">MSKNNWSLQPQDIFNRSPIVPVMVINKIEDAVPLAKALVAGGISVLEVTLRTPCALEAITKIAEEVPDALVGAGTILNEEQLQQAVDAGAQFVITPGATPSLLKAAMEGTVPLIPGVASISEVMTGMSLGYTNFKFFPAEASGGVNALKAFSGPLADIRFCPTGGITPSSYKDYLALKNVDCIGGSWIAPTDAMEQGDWSRITQLCKEAISGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX5</accession>
    <name>B1KGX5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325184.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2567"/>
    <dbReference type="EnsemblBacteria" id="ACA86844">
        <property type="protein sequence ID" value="ACA86844"/>
        <property type="gene ID" value="Swoo_2567"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2567"/>
    <dbReference type="eggNOG" id="COG3188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_296115_0_0_6"/>
    <dbReference type="OMA" id="IAFQDDN"/>
    <dbReference type="OrthoDB" id="113744at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1020" mass="114578" checksum="AEF1C6B2D9D9C496" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGY1</accession>
    <name>B1KGY1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4037</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326622.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4037"/>
    <dbReference type="EnsemblBacteria" id="ACA88293">
        <property type="protein sequence ID" value="ACA88293"/>
        <property type="gene ID" value="Swoo_4037"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4037"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_6"/>
    <dbReference type="OMA" id="CEQYISV"/>
    <dbReference type="OrthoDB" id="1015470at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="32"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="469"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="558" mass="62198" checksum="5AE79FFCC545DB27" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGZ3</accession>
    <name>B1KGZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326634.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4049"/>
    <dbReference type="EnsemblBacteria" id="ACA88305">
        <property type="protein sequence ID" value="ACA88305"/>
        <property type="gene ID" value="Swoo_4049"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4049"/>
    <dbReference type="eggNOG" id="COG0599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070025_2_1_6"/>
    <dbReference type="OMA" id="NVGCTRE"/>
    <dbReference type="OrthoDB" id="1792151at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="33"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="14668" checksum="405F42D3EB8DF9B5" modified="2008-04-29" version="1">MENSRFTVGLEQLSKIDGEAGHNVIESLQDICPDLAKFTIEYPFGDIYSRPALDLKSREIATIAALTALGHCKPQLKVHLNAALNVGCTEDEIKEVLLQMTVYAGFPAALNGMFAFKEVLQESKAIQPSNDLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH03</accession>
    <name>B1KH03_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326644.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4059"/>
    <dbReference type="EnsemblBacteria" id="ACA88315">
        <property type="protein sequence ID" value="ACA88315"/>
        <property type="gene ID" value="Swoo_4059"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4059"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_11_2_6"/>
    <dbReference type="OMA" id="RSAHFYG"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="4"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="16158" checksum="2605FC54C7ADAFC3" modified="2008-04-29" version="1">MRTRQILCPTDFSETASHALKYAIEMANLYHVDIRLLHINSEALGHHNYGIAVETPAELEDEMENFSKEKLTKLAGEVEAYLDEALSVIPVVRSGDVMAQIIEESIEQEVGMIVIASHGHTGLSHLLNPNVSEAVANKAKCPVLVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH18</accession>
    <name>B1KH18_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326659.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4074"/>
    <dbReference type="EnsemblBacteria" id="ACA88330">
        <property type="protein sequence ID" value="ACA88330"/>
        <property type="gene ID" value="Swoo_4074"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4074"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_16_0_6"/>
    <dbReference type="OMA" id="GNWLTEQ"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032681">
        <property type="entry name" value="HlyD_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12700">
        <property type="entry name" value="HlyD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="420" mass="45997" checksum="ED7E3A4D7E2D23C1" modified="2008-04-29" version="1">MIQDTSGQDTVVQASKASRLKWPLIATAAALLVSGLVWSSVGGSNVSESISRSDLRFATLEQGTLTRDIATTGKIVAANAPILYSTDQGTVTLLAKPGDKVELGDVVATIESHQLTNSLKQQEALLEGMQSSLERARLDARREQLKAQQTLDMAKVDLEAADRESRRGDELIENKLISKIDFEKGKDDLHKAKLLSAHAQQEAELTRDTLAFEIKNKASEVNRQKLVVSELERQVAALNIKAPVGGIIGNWLTEQKARIGQSQPILTVVDLSAFEAELAVPESYADELGLGMDVELKFGELTLMGELSSISPEVRNREVTARVRFEQDDRLHLRQNQRLSARVLLENRPNVLMVKRGAFVSTGGGREVYTMNGDIAEQTEIQLGARSMSHIEVLQGGKAGDIWVISSVQPFNQAQQVLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHG1</accession>
    <name>B1KHG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1176</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1176"/>
    <dbReference type="EnsemblBacteria" id="ACA85469">
        <property type="protein sequence ID" value="ACA85469"/>
        <property type="gene ID" value="Swoo_1176"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1176"/>
    <dbReference type="eggNOG" id="COG2863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128253_1_2_6"/>
    <dbReference type="OMA" id="HIPNIGW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767060" evidence="5">
        <location>
            <begin position="33"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="30"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="11965" checksum="D11413C318675716" modified="2008-04-29" version="1" precursor="true">MGVNKNKKSKAIKAISLSIGLAVMGSMSAASAADDQALLNMCKACHGNDGSSEFASTPNLKWQNTAYMVKQLEQFKSGQRQDKTMTKVAKILNKQQMEALASYFNKGKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHN7</accession>
    <name>B1KHN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integron integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325262.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86922">
        <property type="protein sequence ID" value="ACA86922"/>
        <property type="gene ID" value="Swoo_2645"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2645"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_37_0_6"/>
    <dbReference type="OMA" id="KSYLYWN"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011946">
        <property type="entry name" value="Integrase_integron-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02249">
        <property type="entry name" value="integrase_gron"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="101"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="319" mass="36630" checksum="2C803FCC0CB0AA0E" modified="2008-04-29" version="1">MGQATYIEAIRAEIRVRHYSYQTEKSYLYWNRYFIRHCNIRHGDDITPALIEHFLCFLAVQCKVSASTQKQALCAIIFACRHVLKIETKELQFPYAKTPQRIPQVLSSDEAKLIISFLSNYHHLIGSILFGAGLRLKEALRLRIKDIDLSTKSIFVYQGKGQKDRVCMLPNGLVDELTLQMSHVKKIHDRDLVEGFGLASLPISLIKKYRSSAAKFHWQYIFPASRRCIHPSDEYTCRHHIHPTAFSRELRKATTKSNTNKRVTAHTFRHSFATSLLLKGHDIRTIQELLGHSDVKTTQIYTHVIGGHHTGVISPLDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI72</accession>
    <name>B1KI72_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1258</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323896.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1258"/>
    <dbReference type="EnsemblBacteria" id="ACA85550">
        <property type="protein sequence ID" value="ACA85550"/>
        <property type="gene ID" value="Swoo_1258"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1258"/>
    <dbReference type="eggNOG" id="COG0722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_6"/>
    <dbReference type="OMA" id="VMENVAN"/>
    <dbReference type="OrthoDB" id="853329at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="43"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="363" mass="39935" checksum="DF696693B04C0C2F" modified="2008-04-29" version="1">MQQDTINNVHISSEKVLVTPQELKLELPLSEPAYHYVLNARKTVADIVHKRDNRVLIVTGPCSIHDIDSAKEYALKLKTLHDELKDDFFILMRVYFEKPRTTVGWKGMINDPDMDESFDVEKGLRKARELMIWLAELGLPVATEALDPISPQYMSELVTWSAIGARTTESQTHREMASGLSMPVGFKNGTDGKLGVAINALESAASGHRFMGINQQGQVALLQTAGNPDGHVILRGGKSPNYDAKSVEDCEQQLHSANLNARLIVDCSHGNSSKDHKKQKGVCEDVFKQILSGNQSIIGVMLESHLNEGNQSSNKPMSELAYGVSVTDACIDWATTEELLRAGAASLSSVLPNRFDQRKVVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI75</accession>
    <name>B1KI75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1261</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323899.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1261"/>
    <dbReference type="EnsemblBacteria" id="ACA85553">
        <property type="protein sequence ID" value="ACA85553"/>
        <property type="gene ID" value="Swoo_1261"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1261"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_14_3_6"/>
    <dbReference type="OMA" id="MQVHHIH"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="23"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="281"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="365" mass="40217" checksum="9ED51A9A25216FFB" modified="2008-04-29" version="1">MNLDTPSKLDMDELQLTSPTWLHGEVELLCVEKWHETHDVVSFRFQGKSPVKFQFKPGQFLTFMLEINGAVIHRSYTISSSPSRPYSIVVTVKRIEAGVVSNYLAESLQVGDTVMATGPDGVFNLVDIPATKYLFLSAGSGITPMYSMTRWLTDTQVGADIAFLHCAKSMKDLIFKEALDKIAQNNSRFDLSYILESDIEKLTAEYSCRAGRINGQYLSELVSDFQDRTIFVCGPAPFMSGVRAVLSELGFDMSQYHQESFGDDIMQTTLTATLAQTPETKNFMLSIGDRQRALSPEQSLLEGIEAEGLPIIAACRSGVCGACKCQVVEGETESSSQMSLTPDEIEQGFVLACSTKLKSDVTLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI87</accession>
    <name>B1KI87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85565">
        <property type="protein sequence ID" value="ACA85565"/>
        <property type="gene ID" value="Swoo_1273"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1273"/>
    <dbReference type="eggNOG" id="ENOG5031GBA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157989_0_0_6"/>
    <dbReference type="OMA" id="CDSFAMV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766646" evidence="1">
        <location>
            <begin position="19"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="97" mass="10873" checksum="8C7E4050E5249831" modified="2008-04-29" version="1" precursor="true">MYKILTAMLISLMLTACSSMDEPELYHRINEAYDFEVTHCDSFAMVTGIGRGERALRNAKVNAMNHGEELGGTHIVWLQTDHGDPTKVVAVIYKCLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA1</accession>
    <name>B1KIA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2676"/>
    <dbReference type="EnsemblBacteria" id="ACA86952">
        <property type="protein sequence ID" value="ACA86952"/>
        <property type="gene ID" value="Swoo_2676"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2676"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="QVEVHLF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="37033" checksum="2D5E892713D900AE" modified="2008-04-29" version="1">MVFLCWESISVIQHRASQMIVFHTLVMTGSFTLAAKQLNTSTSYVSKQLGALEAELNLQLVQRTTRTLTFTDAGKRFALYCEQMFDLMHDAGANMLDARDDISGTVKLGLPQSFGTLHIIPALELLQQEYPELIFELTLFDHATDMVKESLDIWITNQEKIHDGYVAQRLAHTGFVLVASPEYLLSHGVPEHPQDLVEHNCVIYHSKSRSYDNWTFTQGDEVVDVQVNGNFRIDLSEAVRDRVISGHGIGHLATYLLTDEFQQGKLIPLLPKWQTEQKLPVYAVYPKRKHLPAKFRVIIEFLRSHFGQPAYWDRDLKPWLKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIF1</accession>
    <name>B1KIF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III restriction protein res subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325339.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2726"/>
    <dbReference type="EnsemblBacteria" id="ACA87002">
        <property type="protein sequence ID" value="ACA87002"/>
        <property type="gene ID" value="Swoo_2726"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2726"/>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014765_1_0_6"/>
    <dbReference type="OMA" id="WIYQYHY"/>
    <dbReference type="OrthoDB" id="377818at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="239"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="580" mass="65842" checksum="55E0068940D30EEE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIW2</accession>
    <name>FETP_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable Fe(2+)-trafficking protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1318</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fe(2+)-trafficking protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323956.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIW2"/>
    <dbReference type="SMR" id="B1KIW2"/>
    <dbReference type="STRING" id="392500.Swoo_1318"/>
    <dbReference type="EnsemblBacteria" id="ACA85610">
        <property type="protein sequence ID" value="ACA85610"/>
        <property type="gene ID" value="Swoo_1318"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1318"/>
    <dbReference type="eggNOG" id="COG2924">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170994_0_0_6"/>
    <dbReference type="OMA" id="SKQTMLI"/>
    <dbReference type="OrthoDB" id="2038019at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3880.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00686">
        <property type="entry name" value="Fe_traffic_YggX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007457">
        <property type="entry name" value="Fe_traffick_prot_YggX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036766">
        <property type="entry name" value="Fe_traffick_prot_YggX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36965">
        <property type="entry name" value="PTHR36965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04362">
        <property type="entry name" value="Iron_traffic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029827">
        <property type="entry name" value="Fe_traffic_YggX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111148">
        <property type="entry name" value="SSF111148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000131866" description="Probable Fe(2+)-trafficking protein">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00686"/>
        </source>
    </evidence>
    <sequence length="92" mass="10649" checksum="55275DF6258031E2" modified="2008-04-29" version="1">MARTVNCVYLKKEAEGLGFQLYPGPLGKRIFDNVSKEAWGLWQAKQTMLINEKKLNMMNVEDRGFLETQMVNFLFEGKDVEIEGYVPQKDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ39</accession>
    <name>B1KJ39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2783"/>
    <dbReference type="EnsemblBacteria" id="ACA87059">
        <property type="protein sequence ID" value="ACA87059"/>
        <property type="gene ID" value="Swoo_2783"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2783"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029425_5_5_6"/>
    <dbReference type="OMA" id="TGPHLDW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766700" evidence="1">
        <location>
            <begin position="32"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="177"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="286" mass="30996" checksum="4F86B811BA353E5F" modified="2008-04-29" version="1" precursor="true">MKYISTPSVLSSAVFCCMVISSLLISSHASAQVELVGKMEQGALIRAQVEPGTKVSLNGEAVKVTPKGDFAFGFGREAELNQELKLVYPDGLTQIMPLTISEKEYKIDRVNGISKKIMKPDPKAVERSRKDSKQVKAARAQFSEQNAFTQDFIWPLTGRISGVYGSQRVYNGKPGNPHYGVDVAAKTGTVVVAPADGIISLSVADMFYSGGTVILDHGYGVSSSFLHLSKLYVTEGEAIKQGQPIAEVGATGRVTGPHLDWRVNWYQMRLDPVTIVPSMASVLNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ59</accession>
    <name>B1KJ59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325415.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2804"/>
    <dbReference type="EnsemblBacteria" id="ACA87079">
        <property type="protein sequence ID" value="ACA87079"/>
        <property type="gene ID" value="Swoo_2804"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2804"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_6"/>
    <dbReference type="OMA" id="PNDRSID"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="24919" checksum="D782154A098F645A" modified="2008-04-29" version="1" precursor="true">MRILVVEDDPILSHHLKVQLSELGNQVQVALTAKEGFYQATNYPIDVAIVDLGLPDQDGISLIQSLRDNGLKAPVLILTARVNWQDKVEGLNAGADDYLVKPFQKEELVARLDALVRRSAGFVKPVITSGPLNLDLAAKQVTMHEEVMEVTAFEYQILEYLMRHCHEVVAKQRLLDVVYADKEGDPNTIEVMVSRLRKKLTSGGLDNPIATIRGQGYKFNLPCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJC1</accession>
    <name>B1KJC1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326919.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4340"/>
    <dbReference type="EnsemblBacteria" id="ACA88593">
        <property type="protein sequence ID" value="ACA88593"/>
        <property type="gene ID" value="Swoo_4340"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4340"/>
    <dbReference type="eggNOG" id="COG4989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_8_0_6"/>
    <dbReference type="OMA" id="VVYAWVM"/>
    <dbReference type="OrthoDB" id="1367386at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="12"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="33482" checksum="932157CF8A76B5C0" modified="2008-04-29" version="1">MSNQFQMSDFIAGFWRLASWDYSIQQRLALIEQYLELGVTTMDHADIYGQMQCEALFGEALSLKPSLRSKLQLISKCGIKPAFDSTPERYVNHYDTSREHLLNSVENSLTRLNTDHLDLLLIHRPDPLMNADDVAHAFKHLQQSGKVLNFGVSNFSTAQFELLQSRLTPLGIQLVTNQVEISPANMASLHDGTLDQCQQYKIAPMAWSCLGGGEIITGQNAQAVRLREILHRVADNHQTQDISQIIYAWVAALPSKPKPIIGSGKLQRIQSAVKSKQIKLDKQEWFSIWEASTGHSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJE2</accession>
    <name>B1KJE2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secretion protein HlyD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326940.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4361"/>
    <dbReference type="EnsemblBacteria" id="ACA88614">
        <property type="protein sequence ID" value="ACA88614"/>
        <property type="gene ID" value="Swoo_4361"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4361"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_6_5_6"/>
    <dbReference type="OMA" id="PYNLGER"/>
    <dbReference type="OrthoDB" id="1174564at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="313" mass="34134" checksum="C238FDC1330E0E80" modified="2008-04-29" version="1" precursor="true">MKPLFFMLLPLILTACQGEVSNQALGTLERDRVLLRATVSEIITALPQKEGNRVEKGELLVQFDTRKQLARVAFAKAEVSKAESYLLRLTNGERPEDIASAQANVARTQAALVEANQSYQRSSSLLKQKLTSQATQDAAKANKDKAQAELVVAKENLSKLIAGVRVEDINQAKAALDASIANLSLEEQTLDDLSVIATRSGRLDSLPFNLGERVPSGAVIVAIQADNAPYARVYVPEPYMAKLTIGQKMRVRVDGIETPFIGTLRRLSQESAFTPYYALNQQDRSRLVFLAEVDLGSDADALPTGIPSQVELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG4</accession>
    <name>B1KJG4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326962.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4384"/>
    <dbReference type="EnsemblBacteria" id="ACA88636">
        <property type="protein sequence ID" value="ACA88636"/>
        <property type="gene ID" value="Swoo_4384"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4384"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030532_1_0_6"/>
    <dbReference type="OMA" id="FKWVAIL"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="418" mass="45199" checksum="60E891885FC9BC9F" modified="2008-04-29" version="1">MLTKLKALPEQVKQYLIVTGNYWGFTLTDGALRMLVVLHFHQLGYTPLAIAMLFLFYEIFGVVTNLVGGYLGARLGLNRTMNIGLGLQVVALCMLLVPNSMLTLVWVMAAQGLSGIAKDLNKMSAKSSIKMLVNSDSAQESSQKLYGWIAKLTGSKNALKGAGFFLGGALLSLFGFKSAIAIMAAGLAIIWIMSIVSLKKDLGKAKSKPKFSEIFSKSRSINILSAARLFLFAARDVWFVVALPLYLGSQFGWDHYYVGGFLALWVIAYGFVQTQAPKLTSRADGHPPGGKEALFWVCALAAIPGLIALALMFNVSPELSLLIGLMIFGAVFALNSSLHSFLIVHYASDDGVSLDVGFYYMANAMGRLLGTVLSGYVYQVAGLEACLWISSGMLAITALISLYLPKNQSPLNEGDLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJK2</accession>
    <name>B1KJK2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1383</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324021.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1383"/>
    <dbReference type="EnsemblBacteria" id="ACA85675">
        <property type="protein sequence ID" value="ACA85675"/>
        <property type="gene ID" value="Swoo_1383"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1383"/>
    <dbReference type="eggNOG" id="COG0307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_2_0_6"/>
    <dbReference type="OMA" id="HFVTGHV"/>
    <dbReference type="OrthoDB" id="1276859at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="23798" checksum="9698549461A54C0B" modified="2008-04-29" version="1">MFTGIIESVGTLRKIERRGDDIRLTVASGKLDLGDVRLGDSIATNGVCLTVVECMSDGYVADISAETVSLTGFAHYQVGRKVNLEKAVTPTTRLGGHMVSGHVDGIASVDDRQLRGKAIEFWLTAPAELARYIAHKGSITIDGVSLTVNEVQDNRFRLTIVPHTAGETTLVDMKAGDTVNLEVDLIARHLERLMSYAGDKAQTPESNVTMDLLARSGFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ7</accession>
    <name>B1KJQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1438</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324076.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1438"/>
    <dbReference type="EnsemblBacteria" id="ACA85730">
        <property type="protein sequence ID" value="ACA85730"/>
        <property type="gene ID" value="Swoo_1438"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1438"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053847_2_0_6"/>
    <dbReference type="OMA" id="WNYPKRN"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="6"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="415" mass="45722" checksum="55B9DBD0E393771C" modified="2008-04-29" version="1" precursor="true">MSSWRIKLSLLLTYLVFAILLNSVGVVILQVINNYEVSKSSASVLEGFKDLPIAIVSFFVASYLPRFGYRNAIVLGLVIVTLACIVMPLIPSFAMTKILFLSVGVSFALVKVSVYATVGLITHDRQSHAAFLNTIEGFFMVGVLSGYWIFSLFIDPDSTKSTQWLQVYYWLSLLCAFNILLLLSTPFKQSRQAERKDSAITEFLAMLNLVKLPMVYVFVTSAFLYVLIEQGIGTWLPTFNNEIIRLPTDMSIQVTSIFAACLALGRLSAGVILKRIHWYLLLNICLIAMAALVLLTLPMTNNLEPIGNNDWSSVPLAAWLFPCIGLFMAPIYPAINSVILSALPKDKHAAMTGLIVLFSALGGTCGSMLTGYVFAVFDGQTAFYLILIPILIIMITLRLLKGNVQRSGTVEVVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJS6</accession>
    <name>B1KJS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324095.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1461"/>
    <dbReference type="EnsemblBacteria" id="ACA85749">
        <property type="protein sequence ID" value="ACA85749"/>
        <property type="gene ID" value="Swoo_1461"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1461"/>
    <dbReference type="HOGENOM" id="CLU_2131836_0_0_6"/>
    <dbReference type="OrthoDB" id="2179650at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764580" evidence="1">
        <location>
            <begin position="31"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12600" checksum="FB31EDE2F56BA517" modified="2008-04-29" version="1" precursor="true">MLNKLLIASKAKLKWITLLMATLFSTGVYATSCVQNNNIVTFTGLDSKEGVIYASLSSHDNQCGCSYIRFAPQNTRTEMALSILMAAKLSQNRVRIDLMEHGNCNTAYRVYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK24</accession>
    <name>B1KK24_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326981.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4403"/>
    <dbReference type="EnsemblBacteria" id="ACA88655">
        <property type="protein sequence ID" value="ACA88655"/>
        <property type="gene ID" value="Swoo_4403"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4403"/>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5571">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004043_0_0_6"/>
    <dbReference type="OMA" id="SCTIATY"/>
    <dbReference type="OrthoDB" id="10412at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037221">
        <property type="entry name" value="H-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1463" mass="154685" checksum="0BF3CFADBC02B0A7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK35</accession>
    <name>B1KK35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326992.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4414"/>
    <dbReference type="EnsemblBacteria" id="ACA88666">
        <property type="protein sequence ID" value="ACA88666"/>
        <property type="gene ID" value="Swoo_4414"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4414"/>
    <dbReference type="eggNOG" id="COG2804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013446_10_6_6"/>
    <dbReference type="OMA" id="FSPFGNK"/>
    <dbReference type="OrthoDB" id="749544at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="585" mass="65013" checksum="EBDA1BD46257FF93" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK37</accession>
    <name>B1KK37_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MSHA biogenesis protein MshM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326994.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4416"/>
    <dbReference type="EnsemblBacteria" id="ACA88668">
        <property type="protein sequence ID" value="ACA88668"/>
        <property type="gene ID" value="Swoo_4416"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4416"/>
    <dbReference type="eggNOG" id="COG3267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024125_3_0_6"/>
    <dbReference type="OMA" id="INTLCDN"/>
    <dbReference type="OrthoDB" id="947558at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="42"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="302" mass="33708" checksum="E8EAC5EBD413399C" modified="2008-04-29" version="1">MYQQHFGLAETPFSLTPNTQFFFGLAPHVEALQVLQMALQTGEGFIKVTGEVGTGKTLICRKLINELPKRFHCAYLPNPYLSPAELRWAVALELGLKYSASIDQMQLTGLIQQQLLALSAHGHSIVLVLDEAQALPDESLEALRLFTNLETESRKLLQVVLFAQPELDDRLNLHNFRQLRQRITFSYKLRALSVDEACAYVQHRLSVAGRVGEPLFIEKDIRALAQAARGIPRLINILAHKSLLLSFGEGAERVKRQHVKAAITDTQDANVTGQNRWFWFMGLGVTSLLAGLGIHLFWGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK85</accession>
    <name>B1KK85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327042.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88716">
        <property type="protein sequence ID" value="ACA88716"/>
        <property type="gene ID" value="Swoo_4465"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4465"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="IESANNW"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="37663" checksum="50BA3681FBD1094C" modified="2008-04-29" version="1">MPRPRRTQISIEDTPYYHAWSRTVRRAFLTGVDDYTGKSYEHRREWIEEQILSLADIFAIDVAAYAVMSNHLHLVLRIDIESANNWSDREVVEQWHRCFNGTGLSQKFVKGEVIEEYQVAKLKHLIATYRSRLCDISWFMRCLNEPIARKANIEDNCTGHFWEGRFKSQALLDEAAVLACMAYVELNPIRAKMVDTLENSDHTSIQLRVNAALKGEQPSKLLPFIGDERLNQPKGINFALKDYLELVDETGRIIRDDKRGSISAKSTKILMKLNISSDNWIKLTSEFGELFHGPVGETQSLTRYCEHLQKRRRHFSKSCQHFQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG4</accession>
    <name>B1KKG4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OsmC/Ohr family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324150.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1516"/>
    <dbReference type="EnsemblBacteria" id="ACA85804">
        <property type="protein sequence ID" value="ACA85804"/>
        <property type="gene ID" value="Swoo_1516"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1516"/>
    <dbReference type="eggNOG" id="COG1764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106355_2_1_6"/>
    <dbReference type="OMA" id="YSACFDS"/>
    <dbReference type="OrthoDB" id="1984062at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019953">
        <property type="entry name" value="OHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797">
        <property type="entry name" value="PTHR33797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03561">
        <property type="entry name" value="organ_hyd_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="14526" checksum="31EFE68A17F09012" modified="2008-04-29" version="1">MKKLYETNATASAGRNGKVSSDDGLLSLALSYPKEMGGSGEATNPEQLFAAGYSACFSNAILHVAREVKVPLTEAPVTATVAIGAKEEGGFELTAALSITLELLEAQAVEIVKTAHQVCPYSNAVKGNIDVVLTLNGKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKK7</accession>
    <name>B1KKK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isoquinoline 1-oxidoreductase maturation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325560.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2951"/>
    <dbReference type="EnsemblBacteria" id="ACA87224">
        <property type="protein sequence ID" value="ACA87224"/>
        <property type="gene ID" value="Swoo_2951"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2951"/>
    <dbReference type="eggNOG" id="COG2068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061980_2_0_6"/>
    <dbReference type="OMA" id="QLIETWQ"/>
    <dbReference type="OrthoDB" id="1432587at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="6"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22501" checksum="F809BD986FE3E0BB" modified="2008-04-29" version="1">MKSLIVLLAAGRSRRFNGAKLAQVIDREGTSILEDSYSKLWGVANKVGAELLVILGGHQEQLLPLLPAGAKYLINSEFKTGLSSSIRCAVNHGVKTEADSLLISLADQVAITESDYLSLYRARGGAPVCATFDEQLSAPALFYRDDFDKLAALKGDRGAKPILQMLKQVGRLQTVEMSSAQKDIDTRIELADWLDVRSVSRENHNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN4</accession>
    <name>B1KKN4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="5">ATase</shortName>
            <ecNumber evidence="5">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
            <shortName evidence="5">GPATase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purF</name>
        <name evidence="10" type="ordered locus">Swoo_2980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325587.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2980"/>
    <dbReference type="MEROPS" id="C44.001"/>
    <dbReference type="EnsemblBacteria" id="ACA87251">
        <property type="protein sequence ID" value="ACA87251"/>
        <property type="gene ID" value="Swoo_2980"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2980"/>
    <dbReference type="eggNOG" id="COG0034">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022389_2_1_6"/>
    <dbReference type="OMA" id="ENAQPTF"/>
    <dbReference type="OrthoDB" id="267682at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 7">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="504" mass="55790" checksum="D88366EB5A7B5E43" modified="2008-04-29" version="1">MCGIVGIVGRTSVNQPIYDALTVLQHRGQDAAGIVTVDGNAFRLRKANGLVKDVFEAKHMQRLQGKTGIGHVRYPTAGSSSASEAQPFYVNSPFGISLAHNGNLTNTVELHELLLKRRRHVNTTSDSEVLLNLLADELQQCKNESLSSEEVFDAVAKVHSLTRGAYAVTALIIGQGLVAFRDPFGIRPLVLGKQETELGTEYMIASESVALDAVGFELMRDVAPGEAVYITLDGELYTQQCAHTPSYAPCLFEFVYFARPDSTIDKVSVYGSRVNMGAKLGEKIKREWEDHDIDVVIPIPETSCDTALEIARHLELPYRQGFVKNRYIGRTFIMPGQQERKKSVRRKLNAIGVEFKGKNVLLVDDSVVRGTTSEQIIEMAREAGAKKVYFASAAPEIRFPNVYGIDMPTASELIAHGRDVDEISKMIGADGMIFQDLEDLAEAVRMENPEIKRFETSVFDGNYITNDVDQAYLDHITKLRNDDAKANRSKDIGTNLELHNVCHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR0</accession>
    <name>B1KKR0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325613.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87277">
        <property type="protein sequence ID" value="ACA87277"/>
        <property type="gene ID" value="Swoo_3006"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3006"/>
    <dbReference type="eggNOG" id="ENOG5031IFA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1814496_0_0_6"/>
    <dbReference type="OMA" id="RICIDAP"/>
    <dbReference type="OrthoDB" id="2098898at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="130" mass="14568" checksum="CCEB67FC462FD552" modified="2008-04-29" version="1">MFAKQSGKARSWSVIVFTVLTLFCLTQNSGVIERLINHGHHNAPVNSEVFLSGSTSEVGSDLSHFEFKTCELSEKSMRLCCDTESPVVSLALLFVLALICVLPRDAHLFPVLRPQGKPRRIHLQLCRFQE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKS1</accession>
    <name>AROC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chorismate synthase</fullName>
            <shortName evidence="1">CS</shortName>
            <ecNumber evidence="1">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroC</name>
        <name type="ordered locus">Swoo_3017</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="1">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the chorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325624.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKS1"/>
    <dbReference type="SMR" id="B1KKS1"/>
    <dbReference type="STRING" id="392500.Swoo_3017"/>
    <dbReference type="EnsemblBacteria" id="ACA87288">
        <property type="protein sequence ID" value="ACA87288"/>
        <property type="gene ID" value="Swoo_3017"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3017"/>
    <dbReference type="eggNOG" id="COG0082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034547_0_2_6"/>
    <dbReference type="OMA" id="MLSINAV"/>
    <dbReference type="OrthoDB" id="981870at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0288">FMN</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000115399" description="Chorismate synthase">
        <location>
            <begin position="1"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="293"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <sequence length="364" mass="39119" checksum="9038C46095D7A757" modified="2008-04-29" version="1">MSGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELNEADMQHDLDRRRPGTSRYTTARREPDEVRVLSGIFEGKTTGTSIGLMIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGLRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGIEINGFLSQLGPIKAEALDFSQIEQNAFFFPDPSKLDELDEYMRDLKKSGDSVGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAVKGVEIGDGFEVVTQKGSEHRDLMSPEGFASNHAGGILGGISSGQPIVAHIAMKPTSSISIPGESITAQGEIAEVVTKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSQTPTIGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV8</accession>
    <name>B1KKV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">OmpA domain protein transmembrane region-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_4513</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327090.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4513"/>
    <dbReference type="EnsemblBacteria" id="ACA88764">
        <property type="protein sequence ID" value="ACA88764"/>
        <property type="gene ID" value="Swoo_4513"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4513"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031536_2_0_6"/>
    <dbReference type="OMA" id="KWFLTGE"/>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000498">
        <property type="entry name" value="OmpA-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01389">
        <property type="entry name" value="OmpA_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766776" evidence="12">
        <location>
            <begin position="20"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="13">
        <location>
            <begin position="221"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA88764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="341" mass="36964" checksum="7AABBA025CB3E261" modified="2008-04-29" version="1" precursor="true">MKKSLLAIALMSTFSYANAADVDNTWYIGAGAGQSNYESVDAVSHLGDDSDLAWNAVVGYQLNKYFAVEAGWQDLGTNDDTHLWGGLDGAQSIDVDGFTLGLVGTLPLSEKWFLTGEAGAYQYHLAHQMSADKYVSATDTAPYFGAGVGYKITDSLEVSAKYRRFANIDESAWNTANMDAQTVGIQMVYRFGVKPTPTTAAVVLPAVIKETKPAPRPEPVYETKIEQSSVAVLFGFDSSSLSSTAKAKLDEVIRLSKQSDNDTILLNGQSDNQGDSEYNQKLSEARVQQVADYLNANGVEVQTLEQQATGEQNAHANSRTDRALERRVIITLTSETQVVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD9</accession>
    <name>B1KLD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acylneuraminate cytidylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.43" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324210.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1578"/>
    <dbReference type="EnsemblBacteria" id="ACA85864">
        <property type="protein sequence ID" value="ACA85864"/>
        <property type="gene ID" value="Swoo_1578"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1578"/>
    <dbReference type="eggNOG" id="COG1083">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042930_1_1_6"/>
    <dbReference type="OMA" id="AYHMKEL"/>
    <dbReference type="OrthoDB" id="1345588at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008781">
        <property type="term" value="F:N-acylneuraminate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="25655" checksum="E1A957D517F04E90" modified="2008-04-29" version="1" precursor="true">MKQYAFIFARGGSKGLPRKNVKNLLGKPLIVYSIETALNVTDIDKVFISTDDDEIATIGLASGAEIIPRPAHLATDNSPEWLSWQHAVNWVTSEYGEFERFISLPATSPLRSVEDVESAMHKLQTSNADICISTTPANRSPYFNMIKETGSGHVELVNANSKEVCRRQDAPIVYDITTVVYVSTPRYILNETGLFAGKVAHTVIPKERAVDIDDIYDFKFAEAILSSKGQVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK7</accession>
    <name>B1KLK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325640.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3033"/>
    <dbReference type="EnsemblBacteria" id="ACA87304">
        <property type="protein sequence ID" value="ACA87304"/>
        <property type="gene ID" value="Swoo_3033"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3033"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031701_0_0_6"/>
    <dbReference type="OMA" id="RACQAND"/>
    <dbReference type="OrthoDB" id="997498at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025738">
        <property type="entry name" value="BatD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40940">
        <property type="entry name" value="PTHR40940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13584">
        <property type="entry name" value="BatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764637" evidence="2">
        <location>
            <begin position="23"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="548" mass="60296" checksum="737FF4E262FA9D6C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK8</accession>
    <name>B1KLK8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3034"/>
    <dbReference type="EnsemblBacteria" id="ACA87305">
        <property type="protein sequence ID" value="ACA87305"/>
        <property type="gene ID" value="Swoo_3034"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3034"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_1_6"/>
    <dbReference type="OMA" id="FRYAFWL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="32"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="125"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="22463" checksum="EAA989B01F04A103" modified="2008-04-29" version="1">MNSKMFNFSRNKKPTTTVNSDMVSKQRRYDSLVRALHADIFRYGYWLCGDKHVAEDITQETFLRAWRSLESLKDDKAAKAWLITILRRENARRFERKQFNYSDVEQETIEDHISSSNEDQAEQHLIRRQIAKLELEYREPLLLQVIGGFSGEEIAGILELNRNTVMTRLFRARNQLKDVLEQPQVRGQSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLR9</accession>
    <name>B1KLR9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.11" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325702.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3095"/>
    <dbReference type="EnsemblBacteria" id="ACA87366">
        <property type="protein sequence ID" value="ACA87366"/>
        <property type="gene ID" value="Swoo_3095"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3095"/>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_0_6"/>
    <dbReference type="OMA" id="THGGIIV"/>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018826">
        <property type="term" value="F:methionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="42249" checksum="30E7EFBE9FC952AE" modified="2008-04-29" version="1">MQDKWKLATKVIHAGHIRSSSGALVTPLCQSATFVFDSAEQGGERFAGDQPGYIYTRLGNPTTAELERKMAALEGAEAAVATASGMAAVSSALLANLQHGDHLVASKAVYGCTFSLMTAQFLRFGIEVTLVDFNDLSAIKEAIKPTTKVLFCETPVNPHLDVFDLDAIAKIAQANKLVSIVDNTFMTPLLQQPLTHGIDIVVHSATKYLNGHGDVIAGVICGSNEQIEQIKYETVKDLGGVLSPHDAWLILRGLKTLDVRLARHCDNAECLAYYLLNHEKVTKVYYPGLEGHSGYPLLGTQMKRAGGVIAFELNGAMEQSLQFINSLTLFSIAVSLGDAESLIQHPASMTHSPYSEQERELAGIGESLLRISVGLESVEDLISDLEQALALV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV2</accession>
    <name>RPOZ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase subunit omega</fullName>
            <shortName evidence="1">RNAP omega subunit</shortName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase omega subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Transcriptase subunit omega</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpoZ</name>
        <name type="ordered locus">Swoo_4582</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase subunit omega family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327157.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLV2"/>
    <dbReference type="SMR" id="B1KLV2"/>
    <dbReference type="STRING" id="392500.Swoo_4582"/>
    <dbReference type="EnsemblBacteria" id="ACA88832">
        <property type="protein sequence ID" value="ACA88832"/>
        <property type="gene ID" value="Swoo_4582"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4582"/>
    <dbReference type="eggNOG" id="COG1758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125406_5_3_6"/>
    <dbReference type="OMA" id="NVDNRFQ"/>
    <dbReference type="OrthoDB" id="1972750at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00366">
        <property type="entry name" value="RNApol_bact_RpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003716">
        <property type="entry name" value="DNA-dir_RNA_pol_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34476">
        <property type="entry name" value="PTHR34476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="SSF63562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00690">
        <property type="entry name" value="rpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000121273" description="DNA-directed RNA polymerase subunit omega">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00366"/>
        </source>
    </evidence>
    <sequence length="94" mass="10328" checksum="89FFF4BC911DA523" modified="2008-04-29" version="1">MARVTVEDAVEQIGNRFDMILVAARRARQIAVQGKDPMVEEENDKPTVIALREIELGLVTADTLDADERQTVREREAAEIAAVAAIAEGRNNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW8</accession>
    <name>B1KLW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327173.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4598"/>
    <dbReference type="EnsemblBacteria" id="ACA88848">
        <property type="protein sequence ID" value="ACA88848"/>
        <property type="gene ID" value="Swoo_4598"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4598"/>
    <dbReference type="eggNOG" id="COG4648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108379_0_0_6"/>
    <dbReference type="OMA" id="HFAPWQF"/>
    <dbReference type="OrthoDB" id="1580783at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="20753" checksum="50BE238FB13206E9" modified="2008-04-29" version="1">MRLFSQKALQIVTSVVLLGYPLAVYFGLNYLPAGTIAMVLCSLLILRLIVQKQQVKSMILPVAVGIGLTAASAIAKRHDWLLYYPVVINLSMLALFAYSLKIGPSMVERLARLKEPELPDEATPYLKKVTLIWCGLFVFNGSVALYTACYTSLETWTLYNGLIAYLLIGSLLGGEWLYRTIWLKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM02</accession>
    <name>B1KM02_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005423939.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4632"/>
    <dbReference type="EnsemblBacteria" id="ACA88882">
        <property type="protein sequence ID" value="ACA88882"/>
        <property type="gene ID" value="Swoo_4632"/>
    </dbReference>
    <dbReference type="GeneID" id="51062392"/>
    <dbReference type="KEGG" id="swd:Swoo_4632"/>
    <dbReference type="eggNOG" id="COG4453">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152494_4_0_6"/>
    <dbReference type="OMA" id="MIACDEA"/>
    <dbReference type="OrthoDB" id="1980757at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014795">
        <property type="entry name" value="Vibrio_phage_ICP1_Orf50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08681">
        <property type="entry name" value="DUF1778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="9807" checksum="A1DF589FEBC98D7C" modified="2008-04-29" version="1">MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVISEHESITVEANVFDQFMIACDEAKAPNKALLEAAAFTKSGEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM25</accession>
    <name>B1KM25_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Periplasmic protein thiol--disulphide oxidoreductase DsbE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327229.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4655"/>
    <dbReference type="EnsemblBacteria" id="ACA88905">
        <property type="protein sequence ID" value="ACA88905"/>
        <property type="gene ID" value="Swoo_4655"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4655"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_19_1_6"/>
    <dbReference type="OMA" id="MIGKPFP"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03010">
        <property type="entry name" value="TlpA_like_DsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004799">
        <property type="entry name" value="Periplasmic_diS_OxRdtase_DsbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00385">
        <property type="entry name" value="dsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="35"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="185" mass="21253" checksum="2E3F8641112904C4" modified="2008-04-29" version="1" precursor="true">MKKRLVLFIPLVLFLVMGVFLYKGLFLNPQKLDSALEGKPVPAFQLERLEDRNEIITNESLKGEVALLNVWATWCPSCKYEHPYLMRFARQGILPIYGINYRDERPLAIRELNREGDPYTKNIFDHDGRLGLDLGVYGAPESYLIDHNGIIRYRYAGPIDQRIWSETLLPMIKELQAAAKLDGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMD1</accession>
    <name>B1KMD1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0243</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322893.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0243"/>
    <dbReference type="EnsemblBacteria" id="ACA84544">
        <property type="protein sequence ID" value="ACA84544"/>
        <property type="gene ID" value="Swoo_0243"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0243"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_5_3_6"/>
    <dbReference type="OMA" id="MSEWIDN"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16672" checksum="5314A62E226315A3" modified="2008-04-29" version="1">MDKFDKAIISELRKNARHSISHIAEAVNLSRSAVSERIKKLEQREIIRGYQVLLSESQKEGVSAYFEIQHQCPRCADVVHVFHAIPEVITCRGITGDMDLLVYVQANSMRRLHEIREFIDAQTDIIKIKTHVVMSEWIDNQGESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMF1</accession>
    <name>B1KMF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324295.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1663"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85949">
        <property type="protein sequence ID" value="ACA85949"/>
        <property type="gene ID" value="Swoo_1663"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1663"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_8_1_6"/>
    <dbReference type="OMA" id="SYYREGI"/>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13477">
        <property type="entry name" value="Glyco_trans_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="19"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="183"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="379" mass="42692" checksum="3C8D6F8DC3FA1EB6" modified="2008-04-29" version="1" precursor="true">MKIIIIGGVAQSLINFRGDLIKSFLNANYDVVCISGETDHKYVEQLEKLGCKFIPCKLKRTSLNPLADLLLLFNFIMIFRQEKPDVILAYTIKPVVWGGIASKLFSRTKFYGLITGLGFSFQKGSLKRNILCSLVKRLYKFALSGASGVIFQNSDNQNVFIKNRLINREVSTVVPGSGVNLSHFAQTPLPKGKITFLMISRLLGEKGVREYIEAAKQIRTRYQNVSFHLVGPIDSSPDGIPQNEVLEWQESRYIEYFGSSSDVRPFIEACHVFVLPSYHEGMPRTVLEAMSMARPILTTEVPGCKDTVTPGVNGFLVQHGRADLLAERVGWFIDNEESLQEMGQKSRCMAEDIFDVRKINASLFDIMSLKRNFNDKKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMT2</accession>
    <name>B1KMT2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3189</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325796.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87460">
        <property type="protein sequence ID" value="ACA87460"/>
        <property type="gene ID" value="Swoo_3189"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3189"/>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016813_4_2_6"/>
    <dbReference type="OMA" id="IMLYAMC"/>
    <dbReference type="OrthoDB" id="437016at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018270">
        <property type="entry name" value="C_nuclsd_transpt_met_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00804">
        <property type="entry name" value="nupC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="7">
        <location>
            <begin position="9"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="9">
        <location>
            <begin position="90"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="8">
        <location>
            <begin position="192"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="402" mass="42542" checksum="749D1B6C72E8D85F" modified="2008-04-29" version="1">MQLLISLAGISFLILCGWIFSENRHAIKWRTIIGAFILQAGLAALVLYVPMGQQILGSVSQGVASVLGFADEGIKFLFGDLASNSFVFAIRVLPLVIFISALISMLYYFGIMQWVIKIIGGALQKLLGISRAESLVTTGNIFLSQGESPLLVKPFLPKMTRSELFAVMTGGMASVAGSVLGGYAGLGVELKYLIAASFMAAPGSLMMAKLLVPETSLQECQQEIDMSKSEHGNAVDALASGAMNGMRVAVAIGTMLLAFISVIAMFNAGLEQVGTWFNFEGVTMQSLLGYIFAPVAFLIGIPANEMMQAGGFIGQKLILNEFVAFMDFTSVKEQLSAHSQVIITFALCGFANIGSIAIQLGSIGVMAPERRSDVASLGFKAVLAATLANLMSAVLAGIFVSL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX0</accession>
    <name>RS14_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsN</name>
        <name type="ordered locus">Swoo_4677</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327250.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMX0"/>
    <dbReference type="SMR" id="B1KMX0"/>
    <dbReference type="STRING" id="392500.Swoo_4677"/>
    <dbReference type="EnsemblBacteria" id="ACA88927">
        <property type="protein sequence ID" value="ACA88927"/>
        <property type="gene ID" value="Swoo_4677"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4677"/>
    <dbReference type="eggNOG" id="COG0199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139869_0_1_6"/>
    <dbReference type="OMA" id="FGLCRNQ"/>
    <dbReference type="OrthoDB" id="2032609at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00537">
        <property type="entry name" value="Ribosomal_S14_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023036">
        <property type="entry name" value="Ribosomal_S14_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000128586" description="30S ribosomal protein S14">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00537"/>
        </source>
    </evidence>
    <sequence length="101" mass="11449" checksum="96581840DF33F9EC" modified="2008-04-29" version="1">MAKSSMKAREVKRAKLVAKFAEKRLALKAIINNPTTSDDDRWDAVLKLQGLPRDSSAARQRNRCSQTGRPHGYLRKFGLSRIKLREATMRGEVPGLRKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN72</accession>
    <name>B1KN72_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322918.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0268"/>
    <dbReference type="EnsemblBacteria" id="ACA84569">
        <property type="protein sequence ID" value="ACA84569"/>
        <property type="gene ID" value="Swoo_0268"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0268"/>
    <dbReference type="HOGENOM" id="CLU_2737813_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036105">
        <property type="entry name" value="DiNase_FeMo-co_biosyn_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="71" mass="7985" checksum="353CF4BCA62CA4FB" modified="2008-04-29" version="1">MSNEQDDYIEVKVHRDGVTTTTAKKAVKQKVKMVVSGHDIQPGAKKILRENGIKFYENVDASDFDTDSEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP9</accession>
    <name>B1KNP9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3237</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325843.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3237"/>
    <dbReference type="EnsemblBacteria" id="ACA87507">
        <property type="protein sequence ID" value="ACA87507"/>
        <property type="gene ID" value="Swoo_3237"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3237"/>
    <dbReference type="eggNOG" id="COG2916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117503_0_0_6"/>
    <dbReference type="OMA" id="NIRTFRA"/>
    <dbReference type="OrthoDB" id="1911889at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027454">
        <property type="entry name" value="Histone_HNS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002096">
        <property type="entry name" value="HnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="6">
        <location>
            <begin position="84"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14507" checksum="4217A09D9545809A" modified="2008-04-29" version="1">MSDFLEILTHGRRFKAAVKELSIDDLNELAGKLEKIISERVSQAEAETAAMAERNAKIDEIRKQMEAVGLSVDDLGATAVKSAPKKRAPRPAKYTIVDVNGETITWTGQGRMPTVFKNELDKGRSMDDFLI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS7</accession>
    <name>TILS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tilS</name>
        <name type="ordered locus">Swoo_3265</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text>The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325871.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNS7"/>
    <dbReference type="SMR" id="B1KNS7"/>
    <dbReference type="STRING" id="392500.Swoo_3265"/>
    <dbReference type="PRIDE" id="B1KNS7"/>
    <dbReference type="EnsemblBacteria" id="ACA87535">
        <property type="protein sequence ID" value="ACA87535"/>
        <property type="gene ID" value="Swoo_3265"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3265"/>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018869_2_0_6"/>
    <dbReference type="OMA" id="QTETFFL"/>
    <dbReference type="OrthoDB" id="666797at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015262">
        <property type="entry name" value="tRNA_Ile_lys_synt_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09179">
        <property type="entry name" value="TilS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000213720" description="tRNA(Ile)-lysidine synthase">
        <location>
            <begin position="1"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="32"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <sequence length="470" mass="52772" checksum="3323304344CE9001" modified="2008-04-29" version="1">MTEPSFNTSALIEESIKSAKINVGAKLVLAYSGGVDSEVLAQGLSLYAKSHPEFRYLLVHVHHGLSRNADAWVTHCQKQALDYQLPIEVVQVQVKTGPRLSIEAEARRARYKAITSLMDSADVLLTAHHLDDQLETVLLALKRGLGPKGLSAMGALQVFDGDKQLLRPLLNVSREQIEAKAASLSLPHIEDESNTDDKYDRNFLRLQIIPKLKSRWSAIATTASRSAALCAQQQAVIDDEVSARLPNFIELVPYGEGTALNLDLLSHQTPNWQALLLRGYIESSGFAPVSQIQLEQLLSQLLTAKPDANLEVRIADMLVRRFREKAYLSSYRPHKPKSLESIELTLESEVHFVQEINIPLLSNIRVEVLEDDGGERVRLPLIEEKVSVRFSAVGSLRCHPHNRQKGRELKKLWQEYGVPPWERERVPLIFYNEKLVCAVGYWVEHSFQSAEHETGLRFSIAIVSNECESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNT1</accession>
    <name>B1KNT1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <shortName evidence="7">UDP-N-acetylglucosamine acyltransferase</shortName>
            <ecNumber evidence="7">2.3.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lpxA</name>
        <name evidence="9" type="ordered locus">Swoo_3269</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:67812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="2.3.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transferase hexapeptide repeat family. LpxA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.129" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325875.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3269"/>
    <dbReference type="EnsemblBacteria" id="ACA87539">
        <property type="protein sequence ID" value="ACA87539"/>
        <property type="gene ID" value="Swoo_3269"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3269"/>
    <dbReference type="eggNOG" id="COG1043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061249_0_0_6"/>
    <dbReference type="OMA" id="ECVTINR"/>
    <dbReference type="OrthoDB" id="971098at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00387">
        <property type="entry name" value="LpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="8">
        <location>
            <begin position="174"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="255" mass="27642" checksum="56B3548A52418842" modified="2008-04-29" version="1">MIDKLAYIHPDAKIGNNVTIGPWTYIGAGVEIGDDCWLSSHVVVKGPTVIGKGNKIFQFASVGEDCQDKKYAGEPTRLIMGDNNIIRESVTIHRGTTQDKGETRIGSNNLFMAYVHIAHDCVVGNNVIMSNNASIAGHVHVGDWAILGGLTGVHQFVHIGAHAFTAGYSLILQDVPPFVMASGQPGIPRGLNSEGMKRRGFSKESQMAVRRAYKTLYRKGHTVEEAVAALAEESDDEQVKLLIDFVTSSSRGIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY3</accession>
    <name>B1KNY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4765</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4765"/>
    <dbReference type="EnsemblBacteria" id="ACA89014">
        <property type="protein sequence ID" value="ACA89014"/>
        <property type="gene ID" value="Swoo_4765"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4765"/>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_7_6"/>
    <dbReference type="OMA" id="GMNQAMF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="449"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="503"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="574"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="7">
        <location>
            <begin position="660"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="5">
        <location>
            <begin position="802"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="298"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA89014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1074" mass="122897" checksum="F1F9260DDBE747AD" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP94</accession>
    <name>B1KP94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0364</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323013.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0364"/>
    <dbReference type="EnsemblBacteria" id="ACA84664">
        <property type="protein sequence ID" value="ACA84664"/>
        <property type="gene ID" value="Swoo_0364"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0364"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038152_0_0_6"/>
    <dbReference type="OMA" id="MSGLHGM"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="415" mass="44491" checksum="E2E33DF35BCBFC40" modified="2008-04-29" version="1" precursor="true">MSADIDRNRIFTASCLALTVTAMTFAIRAGILGQLSQDFGLSDAELGWINAMAFLGFPVATILGGLLYNFLGAKKLVLIAFVGHILGLLLTMSADGFWLLLISSFCIGFANGAVEAGCNPLIADIYHKKQTVMLNRFHVWFPGGIVVGALISKAMTDMSFGWQAQIAVMLVPTLIYGYLIISQTFPKTDNINTSTSANLKGLFSPLFLFMAFCMTLTATSELGTQQWIERILGASGASPMLIMAMVTGVMAVGRFFAGPLVHKLNPYGVLLYSAIVTTIGIYSMSLATGNMVYVSALIFALGVTYFWPTMIGFVAENIPQTGALGMSVMGGVGMFAVSMWNPVIGHWIDKGREQAVAAHTTPEIVELAAGQSTLANLSVFPLVLIFAFAGLALYMRQQKQKVSQAQDSAQAESSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE8</accession>
    <name>B1KPE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323067.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0420"/>
    <dbReference type="EnsemblBacteria" id="ACA84718">
        <property type="protein sequence ID" value="ACA84718"/>
        <property type="gene ID" value="Swoo_0420"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0420"/>
    <dbReference type="eggNOG" id="COG3653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016107_1_0_6"/>
    <dbReference type="OMA" id="GCPEVID"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="579" mass="65910" checksum="04F4DD83320514D2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPJ2</accession>
    <name>B1KPJ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1861"/>
    <dbReference type="EnsemblBacteria" id="ACA86145">
        <property type="protein sequence ID" value="ACA86145"/>
        <property type="gene ID" value="Swoo_1861"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1861"/>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029605_0_0_6"/>
    <dbReference type="OMA" id="VACNEQN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019645">
        <property type="term" value="P:anaerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007059">
        <property type="entry name" value="DmsC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04976">
        <property type="entry name" value="DmsC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="617"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="114"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="192"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="682" mass="75027" checksum="B85A309DA3D2A044" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ2</accession>
    <name>B1KPQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3316"/>
    <dbReference type="EnsemblBacteria" id="ACA87585">
        <property type="protein sequence ID" value="ACA87585"/>
        <property type="gene ID" value="Swoo_3316"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3316"/>
    <dbReference type="eggNOG" id="ENOG5032TY3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137967_0_0_6"/>
    <dbReference type="OMA" id="LGIWDWF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="18258" checksum="5608A8F3CC93F9BC" modified="2008-04-29" version="1">MEQGDQESAVTKTVLEDIEIMNEADALPIRQDPIIEKLLKKLPKEIADSYTDTQLQGFRIALGDRTWAKHFIDNRGTFSFPFVRLRFFYVFLLGKNKRAYTRREKHASMLMFVGLVLSFIAISILLGLFTLYILKSAMGIDLLEGTSLGVWDWFRDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ91</accession>
    <name>B1KQ91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323095.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84746">
        <property type="protein sequence ID" value="ACA84746"/>
        <property type="gene ID" value="Swoo_0448"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0448"/>
    <dbReference type="eggNOG" id="ENOG5033XG2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430759_0_0_6"/>
    <dbReference type="OMA" id="YSFDAQQ"/>
    <dbReference type="OrthoDB" id="718413at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="644" mass="74065" checksum="44A4783F651314DA" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI4</accession>
    <name>B1KQI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family with aminotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324569.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1939"/>
    <dbReference type="EnsemblBacteria" id="ACA86223">
        <property type="protein sequence ID" value="ACA86223"/>
        <property type="gene ID" value="Swoo_1939"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1939"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_0_6"/>
    <dbReference type="OMA" id="ARVFVCQ"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="476" mass="52656" checksum="058E2F9C791BE4EB" modified="2008-04-29" version="1">MPIKKYQLVADTISQQILTGYFQPGEKIPSVRASCEQFHVSMTTVQAAYEILEDNGLVASRPSSGYFVSRLADTEHLTPIKPQGISVYNRMISVLNDCHKEGVINLGTAVVSPSLLPTHQIKKILNKLTRDHMLELVTPEFSSGYPRLRREFAKRMLNVNVEVHPDDILVTGGCQDAIALALSAVANAGDVIAVESPCFPGLLQVIESLDMKALPLPCSGSLGMKPDTLQDALQSWPISAIVLVPSFSNPTGSLMPIESRKRVIALVEEYDIALIEDDLFSELNYQDKPVPAIKSLERKGNVIYCSSVSKSLGSGFRLGWLCGGKYHSKIMKLKAFRNVSEPLIIQMLIAELMKQGGYSKHLKKLKIALHQNQKLMQSCIKKSFPKGTLVNSCDGGYVLWVQLPDLCDSRELFTQAIKSGVAFFPGDVFSPHEHYLSYIRFNLAVKWCQEIEQAVISLGKLVKLQLERSAAQLPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQK9</accession>
    <name>B1KQK9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1964</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324594.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1964"/>
    <dbReference type="EnsemblBacteria" id="ACA86248">
        <property type="protein sequence ID" value="ACA86248"/>
        <property type="gene ID" value="Swoo_1964"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1964"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_72_6"/>
    <dbReference type="OMA" id="FEYDNPG"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="194"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="427" mass="47775" checksum="347B351F7F1A7B29" modified="2008-04-29" version="1">MSERLPKILVVDDEPNNLRVYERILAPLNLDIVKAGSGLKALAVAHKHDFFLILMDVQMPGMDGFETASLILDHPKTSHIPVIFITAFARDETFEFKGYMNGAVDYLVKPINDEILKSKAGVFLELYKERLRLDKAFKTKKKAEEELKVHKENLEEIVKARTQELQHSIEHLLTTQDKLVKVEKMASLGRLVSGVAHELNTPIGICVTAASFLEEETCRISEHLQDESLSAEDLTSFCESSIQGSEMLLSNLSRATNLIKKFKLVAVDVSTEELSNLNVIAHIDEIIIEILPALDLTHHQITIEGDKGIVVETYPETLKQVLKELLLNSITHAFEEDIKGHVMIKVEKVDERVRLTFRDDGCGIEADTLAMVFEPFFTTRRGSGASGLGLYIVFNLATHVLKGEVICNSTLGKGTEVIITFPIEHSY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM2</accession>
    <name>SYM_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="1">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">metG</name>
        <name type="ordered locus">Swoo_1977</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324607.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQM2"/>
    <dbReference type="SMR" id="B1KQM2"/>
    <dbReference type="STRING" id="392500.Swoo_1977"/>
    <dbReference type="EnsemblBacteria" id="ACA86261">
        <property type="protein sequence ID" value="ACA86261"/>
        <property type="gene ID" value="Swoo_1977"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1977"/>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_7_0_6"/>
    <dbReference type="OMA" id="SDMHGTP"/>
    <dbReference type="OrthoDB" id="761140at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02800">
        <property type="entry name" value="tRNA_bind_EcMetRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004495">
        <property type="entry name" value="Met-tRNA-synth_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00399">
        <property type="entry name" value="metG_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000093733" description="Methionine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-binding" evidence="1">
        <location>
            <begin position="587"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="332"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="688" mass="77508" checksum="A136AD15CA77DA38" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQQ6</accession>
    <name>B1KQQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324641.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2011"/>
    <dbReference type="EnsemblBacteria" id="ACA86295">
        <property type="protein sequence ID" value="ACA86295"/>
        <property type="gene ID" value="Swoo_2011"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2011"/>
    <dbReference type="eggNOG" id="COG4990">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069568_0_0_6"/>
    <dbReference type="OMA" id="FNAHNLV"/>
    <dbReference type="OrthoDB" id="756899at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026935">
        <property type="entry name" value="BtrH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032369">
        <property type="entry name" value="DUF4872"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14399">
        <property type="entry name" value="BtrH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16169">
        <property type="entry name" value="DUF4872"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BtrH_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4872" evidence="2">
        <location>
            <begin position="153"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="331" mass="37444" checksum="042B718D79D342AB" modified="2008-04-29" version="1">MTMLDVSAFSGVHCESTTMVNLLSQRGIDISEAMVFGLGRGLDYIYWKSKLMPYPFIGGRVKPDKLTEFFSENLDITIIRKETGSIDKAWQNLVSEIDAGNLVGLKLDSYFLEYCSETFHFPSHYLTCYGYDNERVYLIDSMGSEERYSTSRDSLSKARSFKGPMSSKSLSYTLAEHDIKFDLEEVIPKAITQNSESYLNPPIKNMSFKGICKTSEVMKDWLTTLENPKENLASIAYIMEHAGTGGGLFRKLWATYLQECSQIITHPGLDDISARFFEIGEAWSQVSNLLENTAELLDKRLLLEASSILLRIAEDEKSAMKDLHSLVINKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT3</accession>
    <name>B1KQT3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326024.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87689">
        <property type="protein sequence ID" value="ACA87689"/>
        <property type="gene ID" value="Swoo_3421"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3421"/>
    <dbReference type="HOGENOM" id="CLU_1833854_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="15736" checksum="9124BAFB30116D7E" modified="2008-04-29" version="1">MKLENRDIAMNKQASGEADAEEELFYSELSQFELAENDTYLQSKTPLDDEQSLSKFARIKLEGTSGFFGQFIYLINMLDVAIEVTLSNVMTRYNQQPGWEKTESYTIPPKQKLHLGTSSSGKVANGANYEYSLLSVKASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU0</accession>
    <name>B1KQU0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326031.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3428"/>
    <dbReference type="EnsemblBacteria" id="ACA87696">
        <property type="protein sequence ID" value="ACA87696"/>
        <property type="gene ID" value="Swoo_3428"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3428"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_13_6"/>
    <dbReference type="OMA" id="MAHRSFY"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="159"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="371" mass="41909" checksum="1D0B034E0392DF9B" modified="2008-04-29" version="1">MLRHSLILDNEPSALRKLKHIHLSTKVIYPAITRIAVALYDSDTGMVRTFIYSGDDTPLNHYYALLKDCYSLNQIAETQQSRLEQDLSVFENSKHLHAQKIFEAGFRSSYSLPIIIDDGLVGFIFFNAEQTQAFEPACLDHLELVGNLISLVISSELASIRTLASTMRTAIDVTHFRDPETGEHLQRMAHYSRLIVSKIADEFDLDDNFAEHLFLFAPLHDIGKITIPDEILLKNGKLLPKERALMQTHSIEGYKLVDRLLENYHLNSLSHTHMLRNIVLYHHESLDGKGYPEGLVGDEIPIEARVVAVADIFDALTSERPYKQAWSNQQAAEELTKLAGVKLDASCVNALLASMDEVELIQHTYRESTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQV8</accession>
    <name>B1KQV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YfaZ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326049.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3446"/>
    <dbReference type="TCDB" id="1.B.68.1.2">
        <property type="family name" value="the putative beta barrel porin-5 (bbp5) superfamily"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87714">
        <property type="protein sequence ID" value="ACA87714"/>
        <property type="gene ID" value="Swoo_3446"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3446"/>
    <dbReference type="eggNOG" id="ENOG50330PP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1502480_0_0_6"/>
    <dbReference type="OMA" id="INLEAGW"/>
    <dbReference type="OrthoDB" id="1364117at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009998">
        <property type="entry name" value="YfaZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07437">
        <property type="entry name" value="YfaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765135" evidence="1">
        <location>
            <begin position="22"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="19420" checksum="96B8340AC45AE898" modified="2008-04-29" version="1" precursor="true">MRLSLLSSLLILSSVSVTAFANDFSVGLNDDVISTDLAIDLNKNTNAVFGYIYSNDGGHLTSAAMHISHDAGIHHFEVGAKFSYVWAKQSANGSAVGVGGRYKMDLGSSLSFHASGYYAPSVLSFGSVDGQYELDSKMQFQLNPSLALFAGYRNIRFQYDYADNSTFDSGFYIGARARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR19</accession>
    <name>B1KR19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Di-haem cytochrome c peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323184.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0540"/>
    <dbReference type="EnsemblBacteria" id="ACA84836">
        <property type="protein sequence ID" value="ACA84836"/>
        <property type="gene ID" value="Swoo_0540"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0540"/>
    <dbReference type="eggNOG" id="COG1858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034652_5_0_6"/>
    <dbReference type="OMA" id="DEEYHNI"/>
    <dbReference type="OrthoDB" id="52724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765140" evidence="6">
        <location>
            <begin position="19"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="64"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="293"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="499" mass="54246" checksum="5FC30729C8C2E599" modified="2008-04-29" version="1" precursor="true">MRSKSLLLVLSTSLLLSACSDSDSQDETALEQEVVTKELRGEIRLASLSGDPSLNRSVPEASSPLAVLGMQLFYSQALSGDMDTACVSCHHPKLGGGDNLALSIGVEAADPLLLGPGREHSSAGHDYDGGPTVPRNAPTTFNIALWDRAIFHDGRLESIEGTENMNGEGTNMVSPDSPDRATPDESAANLTVMQAMFPVTSSEEMKGHHFQEYDNQEIRQYLVERLRGETGELVTNEWLAAFQLGLQDPDGTAESLITQTNIFTAIGEFERSQVFVNSPWKSFVQGDDDAISLNSKKGALIFFKPQEQGGANCASCHKGDFFTDEEYHNIAMVQVGRGKGDGESGSNDFGRFKVTQLERDKFAFRTPSLLNITQMGPYGHAGSYHSLEAVVRHHLDVNDAINNYDADANIEQQGVQTQNMMSNTLAALNKLNAERNAGTEGVLQDRALSDEEFDQLISFLHTLTDSCIADADNTQCLAPWIPGDDIADPDGLRLEAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR22</accession>
    <name>B1KR22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EndA/NucM nuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323187.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0543"/>
    <dbReference type="EnsemblBacteria" id="ACA84839">
        <property type="protein sequence ID" value="ACA84839"/>
        <property type="gene ID" value="Swoo_0543"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0543"/>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2374">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_619315_0_0_6"/>
    <dbReference type="OMA" id="DGWNINS"/>
    <dbReference type="OrthoDB" id="1114630at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
        <property type="entry name" value="PTHR33607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04231">
        <property type="entry name" value="Endonuclease_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764771" evidence="2">
        <location>
            <begin position="28"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="466" mass="51330" checksum="A01D4F29F0DDE566" modified="2008-04-29" version="1" precursor="true">MFYQLKHKVNRIGAIFIAAFITIPASAEIPANYYQSVDESTPESLRNSLHQIIKGHTKIPYTSSSTDTWDVLEQADEDPNNSNNVIDVYKNASYRKVGGGNSNYNREHSWPKSYGFPNNVSSNYPYTDMHHLFIANGSYNSSRSNKPYADCTSCNEKVTLLNDGRGGSATESNWTVGSFESGSWETWEGRKGDVARALMYMAIRYEGGSHAVTGHMEPDLILTDDRSLIGASNTGSNIAVAYMGLRAELIDWSREDPVDDYELRHNEVVFTYQGNRNPFIDHPEYIACVFEEICSGNGGGTPPPASTNAWINEIHYDNRGGDVNESVEILAPAATNLLNWRIEAYNGNNSSLYKTVELSGTVPDQQNGFGSINFNIKGIQNGSADGLALINPQGEVVQFLSYEGTLVAQNGSAEGMESTDIGVMETNSTQSGYSLQLSGHGQEYSDFIWQSPMQNSRGSINHNQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR70</accession>
    <name>B1KR70_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323235.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0591"/>
    <dbReference type="EnsemblBacteria" id="ACA84887">
        <property type="protein sequence ID" value="ACA84887"/>
        <property type="gene ID" value="Swoo_0591"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0591"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_4_6"/>
    <dbReference type="OMA" id="RFMVRYP"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="304" mass="34285" checksum="E7AC7FBB49461049" modified="2008-04-29" version="1">MYHLNDLQLAIRIAELASISAAGRELGMTPAAASAALQRLEQKLDCQLFARSTRSMKLTEEGRLFIESGRQALTLLEGASNALADNRGELKGEIRIALPSDIGRSLIRPWLDEFAAQYPQLTLSLYFGDQMTDLIGQNVDLALRYGHLEDSNLMRRQLAMTPRVAVASPDYLAKQGTPKHPHELSQHKILILNRGGEPWHKWHFSQKGEEFDINVRGARQCNDGAVLREWALDGMGIAYKSWLDVAADVHQGRLKLLFADQLASKTPLQLVHLQTDYPKFKVRCIMDLLSDKIQEFQQIYPLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRC7</accession>
    <name>B1KRC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324680.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2050"/>
    <dbReference type="EnsemblBacteria" id="ACA86334">
        <property type="protein sequence ID" value="ACA86334"/>
        <property type="gene ID" value="Swoo_2050"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2050"/>
    <dbReference type="eggNOG" id="ENOG5031A7H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088249_0_0_6"/>
    <dbReference type="OMA" id="HQYLNEP"/>
    <dbReference type="OrthoDB" id="960110at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="30299" checksum="9975C24BD27BEDE5" modified="2008-04-29" version="1">MFEPFLTQPEIIKVDKQCKLRVSLHETTADFSLLQVMDGHIGEFIVVSVAPTELSIMVRLHPFLCVNVESSSSEPVGAESVSRSVGQGWRLFSSLGVSPSMCAQELKRGVSITLSFDQFVHFSLEGGSQWEMVPLEKDNRLFHGPKALLEARALVARGVNYELSSEQLLLNISELEKVRGKLIKFGESVSVLGQARLSDEVQDLSAQLMKKKQWLSRQYHHSVERLNWQTSANHGQKHDLQSRQLEYYRLLSTTATNEMVQQLIKDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRJ3</accession>
    <name>B1KRJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326092.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3493"/>
    <dbReference type="EnsemblBacteria" id="ACA87758">
        <property type="protein sequence ID" value="ACA87758"/>
        <property type="gene ID" value="Swoo_3493"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3493"/>
    <dbReference type="HOGENOM" id="CLU_2481578_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="87" mass="9592" checksum="5E5A122437C7BC5A" modified="2008-04-29" version="1">MELNEAIQSFNKLLSKHGVKGMKLSDVRTASSARTVLSKFGGMGSINDIYICTANGHNIKPEQEAAANAELHELLECIYQHCKDRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRN7</accession>
    <name>B1KRN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326135.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3538"/>
    <dbReference type="EnsemblBacteria" id="ACA87802">
        <property type="protein sequence ID" value="ACA87802"/>
        <property type="gene ID" value="Swoo_3538"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3538"/>
    <dbReference type="HOGENOM" id="CLU_1757582_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="16212" checksum="B9C4B569A2729F40" modified="2008-04-29" version="1">MSWTELLTEPRRVTGVYCGTPSLKDFLIEKVIIETSRVIIHGDFKAPPSPLPKRWAENGYTHASARISASGVVILNMSGGPRTGVDRNNCLVGNSVNLCIEESGDTWSPKEGLVFPYKILSCESSFMTFNFICEHIDVTVEGYGPSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCV9</accession>
    <name>B1KCV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0033"/>
    <dbReference type="EnsemblBacteria" id="ACA84334">
        <property type="protein sequence ID" value="ACA84334"/>
        <property type="gene ID" value="Swoo_0033"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0033"/>
    <dbReference type="eggNOG" id="COG5628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112329_1_1_6"/>
    <dbReference type="OMA" id="RFAHAKN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17971" checksum="F7757DE7DAC2EB62" modified="2008-04-29" version="1">MMNIVKVDDSNAHVYANLYQGYSAEFSKIIDDKPDENGVFEIYPRLKGSVTGYLLYVEGIPAAITAIDETSPKAYEICDFYVLPCFRKNKVGKRFISSLFECLGGSWEIKQVAGAEHAISFWRDVVSDYTSDDYVEDVYEDHKWGTVTRQRFAHAKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ6</accession>
    <name>B1KDJ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0702"/>
    <dbReference type="EnsemblBacteria" id="ACA84997">
        <property type="protein sequence ID" value="ACA84997"/>
        <property type="gene ID" value="Swoo_0702"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0702"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_1_1_6"/>
    <dbReference type="OMA" id="PSMQQLY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="6">
        <location>
            <begin position="144"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="5">
        <location>
            <begin position="385"/>
            <end position="946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="948" mass="102591" checksum="8A1DE06DA5E1713C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ4</accession>
    <name>B1KDQ4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arsenate reductase</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2168</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutaredoxin]-dithiol + arsenate + glutathione + H(+) = arsenite + glutathionyl-S-S-[glutaredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:22016"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:17668"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29242"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:48597"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:146199"/>
            <dbReference type="EC" id="1.20.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324795.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2168"/>
    <dbReference type="EnsemblBacteria" id="ACA86451">
        <property type="protein sequence ID" value="ACA86451"/>
        <property type="gene ID" value="Swoo_2168"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2168"/>
    <dbReference type="eggNOG" id="COG1393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116644_0_1_6"/>
    <dbReference type="OMA" id="MQRPIVT"/>
    <dbReference type="OrthoDB" id="1650947at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03034">
        <property type="entry name" value="ArsC_ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006659">
        <property type="entry name" value="Arsenate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00014">
        <property type="entry name" value="arsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="116" mass="13160" checksum="C24298CA510733F2" modified="2008-04-29" version="1">MTQVTIIHNPRCSKSRQTLALLEENKCDIQVVEYLKSPLVKSEIEGLLEKLNLTAREIMRTKETEYKEQGLGELNLTEEQLIRAIVKTPKLLERPIVLANNKAAIGRPPENVLSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDR0</accession>
    <name>B1KDR0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324801.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2175"/>
    <dbReference type="EnsemblBacteria" id="ACA86457">
        <property type="protein sequence ID" value="ACA86457"/>
        <property type="gene ID" value="Swoo_2175"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2175"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_14_1_6"/>
    <dbReference type="OMA" id="RVVVYFY"/>
    <dbReference type="OrthoDB" id="1996723at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="17225" checksum="154A65544DEAE6C3" modified="2008-04-29" version="1">MKTLTSGELAPMFTLKNQQDESISLEACLAQGPVLVYFYPKASTPGCTVQACGLRDSREDLSELNVTVLGISPDPVAKLARFSDKQSLNFSLLSDEDHAIADAFGVWGEKKFMGKIYDGIHRLSFLIGQDGKVAHVFNKFKTKDHHEVVLKHLKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDR1</accession>
    <name>B1KDR1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycine cleavage system transcriptional repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324802.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2176"/>
    <dbReference type="EnsemblBacteria" id="ACA86458">
        <property type="protein sequence ID" value="ACA86458"/>
        <property type="gene ID" value="Swoo_2176"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2176"/>
    <dbReference type="eggNOG" id="COG2716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095322_0_1_6"/>
    <dbReference type="OMA" id="TGGTMLN"/>
    <dbReference type="OrthoDB" id="1859752at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016867">
        <property type="entry name" value="GcvR"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028103">
        <property type="entry name" value="GcvR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="93"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR028103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="20000" checksum="F9ED058A76173B98" modified="2008-04-29" version="1">MSNHLVVTAMGADRPGIVSKFARLASECDCDIVDSRMALFGNEFTLIMMLSGSWASITKMESTLPGLSVELELMTVMKRTSKHTAQHYVSRLEVTFNGKDQRGTMRKITQFLAERSLDLAAVRSHAEEDENGNPTQAVFLTINVPEKVELEKLEISINELAQEMSLDCTIERMRELTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX0</accession>
    <name>B1KDX0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Swoo_3712</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326304.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3712"/>
    <dbReference type="EnsemblBacteria" id="ACA87972">
        <property type="protein sequence ID" value="ACA87972"/>
        <property type="gene ID" value="Swoo_3712"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3712"/>
    <dbReference type="eggNOG" id="COG1686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027070_8_1_6"/>
    <dbReference type="OMA" id="QNTHFQT"/>
    <dbReference type="OrthoDB" id="1499212at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015956">
        <property type="entry name" value="Peniciliin-bd_prot_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012907">
        <property type="entry name" value="Peptidase_S11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037167">
        <property type="entry name" value="Peptidase_S11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07943">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00936">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69189">
        <property type="entry name" value="SSF69189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 17" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766482" description="Serine-type D-Ala-D-Ala carboxypeptidase" evidence="15">
        <location>
            <begin position="25"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="PBP5_C" evidence="16">
        <location>
            <begin position="280"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="12">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA87972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="390" mass="43137" checksum="CC40F34EE7E8315A" modified="2008-04-29" version="1" precursor="true">MNFLNRPLKSLILATSLASSFVFAAPVVTPNAPTVAAKAFVLMDYNTGQVIAEENAYESLNPASLTKMMTSYVIGHEIKVGNISPNDQVTISKKAWSKNFPDSSKMFIEVGKQVTVDDLNHGIIIQSGNDACVAMAEHIAGTEDGFVDLMNSWAKQLGMQDSYFENSHGLDSENHKTTAYDMAILGAALIRDVPEEYVLYKKKSFTYNGIKQYNRNGLLWDKSMHVDGIKTGHTSGAGYNLVTSATKDGMRLVAVVMGTKSEAARKAESKKILNYGFRFFETITPYKAGDSFVTQKIWYGDKESVDLGVTTDTPITINRGQAKNLKANFELTKELTAPLAKGETVGRIYFQLNGKDIAQFPLVTLQEVNEGSWFSKLMDYFTQMFTGWFS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX3</accession>
    <name>LIPA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipoyl synthase</fullName>
            <ecNumber evidence="1">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Lip-syn</fullName>
            <shortName evidence="1">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lipA</name>
        <name type="ordered locus">Swoo_3715</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326307.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDX3"/>
    <dbReference type="SMR" id="B1KDX3"/>
    <dbReference type="STRING" id="392500.Swoo_3715"/>
    <dbReference type="EnsemblBacteria" id="ACA87975">
        <property type="protein sequence ID" value="ACA87975"/>
        <property type="gene ID" value="Swoo_3715"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3715"/>
    <dbReference type="eggNOG" id="COG0320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033144_2_1_6"/>
    <dbReference type="OMA" id="PYCDIDF"/>
    <dbReference type="OrthoDB" id="1184806at2"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000099635" description="Lipoyl synthase">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="80"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <sequence length="321" mass="36349" checksum="2D22595CFF10D2EE" modified="2008-04-29" version="1">MSRPERLQPGVKLRDADKVSRIPVKVVPSERETMLRKPDWLRVKLPSSSQRIDEIKQALRSNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLKPDAQEPKKLAQTIKDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRLLNPEIKIETLVPDFRGRIDAALDILATEPPDVFNHNLETAPMHYRKARPGANYQWSLDLLKKFKERHPDVPTKSGLMMGLGETNEEIAQVLKDLRAHNVEMLTLGQYLQPSKFHLPVERYVPPAEFDELRVFAEEIGFTHAACGPMVRSSYHADLQAQGKEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDZ2</accession>
    <name>B1KDZ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor plug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326326.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3735"/>
    <dbReference type="EnsemblBacteria" id="ACA87994">
        <property type="protein sequence ID" value="ACA87994"/>
        <property type="gene ID" value="Swoo_3735"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3735"/>
    <dbReference type="eggNOG" id="COG4206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_18_5_6"/>
    <dbReference type="OMA" id="GHWAVNA"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764731" evidence="5">
        <location>
            <begin position="37"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="66"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="218"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="628" mass="69887" checksum="41FF8CC65D3AF553" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE41</accession>
    <name>B1KE41_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0732</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323374.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0732"/>
    <dbReference type="EnsemblBacteria" id="ACA85027">
        <property type="protein sequence ID" value="ACA85027"/>
        <property type="gene ID" value="Swoo_0732"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0732"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="MSNEIEA"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="243"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="283"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="555" mass="59919" checksum="4BA449435E57F579" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE59</accession>
    <name>B1KE59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flp pilus assembly protein CpaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323392.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0750"/>
    <dbReference type="EnsemblBacteria" id="ACA85045">
        <property type="protein sequence ID" value="ACA85045"/>
        <property type="gene ID" value="Swoo_0750"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0750"/>
    <dbReference type="eggNOG" id="COG3745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057068_2_1_6"/>
    <dbReference type="OMA" id="AWATKNY"/>
    <dbReference type="OrthoDB" id="2060643at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006190">
        <property type="entry name" value="AFP_Neu5c_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017592">
        <property type="entry name" value="Pilus_assmbl_Flp-typ_CpaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031571">
        <property type="entry name" value="RcpC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16976">
        <property type="entry name" value="RcpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03177">
        <property type="entry name" value="pilus_cpaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50844">
        <property type="entry name" value="AFP_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFP-like" evidence="1">
        <location>
            <begin position="52"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="33084" checksum="63CDB8C70A1DF507" modified="2008-04-29" version="1" precursor="true">MQIKSFDFNWVLLIIAIVLGSIAAWATKNYFITKEQELIAELSKDNIKMAQVVVATQELRKGDIISEANMSVRKIQADTLPLDAIHPKDFNQIVGQMLLEPMSPGRPLMGTYLPGHKAEQFSDILKEGQRAVTINIDELNSTAGMLVPSDHIDLLLSFDEESGDIERKKLQLLLENVTVLATGRQSVDVNPELADTLYDNPNAYNTVTLALSVHDAARVTLAKEKGKFVTFLRNQTESLALDFISLHEQQLFGQADDLLNQEVEMIVGGSGMKTTVQAYPLPESVLEQLSQYKNKTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI8</accession>
    <name>B1KEI8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324909.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2285"/>
    <dbReference type="EnsemblBacteria" id="ACA86566">
        <property type="protein sequence ID" value="ACA86566"/>
        <property type="gene ID" value="Swoo_2285"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2285"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074288_0_0_6"/>
    <dbReference type="OMA" id="GHAFGTF"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="64"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="300" mass="32643" checksum="EFD7684593A7083A" modified="2008-04-29" version="1" precursor="true">MKKQLLLTVSVLSIGLVVYLGLLYPFAMLEARTPVGETQSMILANGNRMAWHVSGTGPRITLVASLGREASDFNELVLSLNKAGYRTLAVEAPGIGGSELLEKPISLYRLADDVAQIVHHDIAETGNAETVLLIGHAFGNRVMRATASKYPDIAKGVVLIAAGGQREVEPKARQALRNSITPYLTASHREEAIRYAFFAEDNEVPDYWLRGWYLQTALLQVSAVEHTADKLWQQAGGLPMMILQAERDTIAPIKDAADLLKVQLGDQLSVEIIENTGHALLPEAPTDIARAVLIFAKGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN4</accession>
    <name>B1KEN4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PepSY-associated TM helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326380.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3790"/>
    <dbReference type="EnsemblBacteria" id="ACA88049">
        <property type="protein sequence ID" value="ACA88049"/>
        <property type="gene ID" value="Swoo_3790"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3790"/>
    <dbReference type="eggNOG" id="COG3295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087903_0_0_6"/>
    <dbReference type="OMA" id="IHSGRFF"/>
    <dbReference type="OrthoDB" id="1247857at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032307">
        <property type="entry name" value="PepSY_TM-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40115">
        <property type="entry name" value="PTHR40115"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="265" mass="29597" checksum="AF9EB37C641152B0" modified="2008-04-29" version="1" precursor="true">MTRKHHLSGRNSTSLMLKRQVRPWHRWLGIFSAVFVLLIAISGVLINHSNQLSIDSAHVKQAWLLDYYGIKTPSNIHIYQTSPLLANSDNLVWVDKHLALEADSAIRGIVPFDDMLIAIDNSNLYLISNEGVLLEKQDITTGLPSGLTAIANDGQIWLNTNSGSYMADSDLIEWTAAKPFAPLPWSTPLTEVGNDSVKSSAQIVSLQARSHHLTWERVLLDIHSGRFFGALGPWFMDLVALALIIMSISGVYLWIQHKPKRVKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ2</accession>
    <name>B1KEQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Secretion protein HlyD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3808</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326398.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3808"/>
    <dbReference type="EnsemblBacteria" id="ACA88067">
        <property type="protein sequence ID" value="ACA88067"/>
        <property type="gene ID" value="Swoo_3808"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3808"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023976_4_2_6"/>
    <dbReference type="OMA" id="AVLIRYQ"/>
    <dbReference type="OrthoDB" id="1395473at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006144">
        <property type="entry name" value="Secretion_HlyD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00543">
        <property type="entry name" value="HLYD_FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="419" mass="46889" checksum="833763E03F80E2BA" modified="2008-04-29" version="1">MEEPSPSKQLFRKEVLERGDSNSLGTVFLRQPKEYQWIAILMFLVVSGLLVFLFVGTYTKYADVFGVITVDKGLVKVSARREGQIIEQMVKQGDSVTKGDLLYVISTDRHSSFDQNLDQTILIQQMELQSSLERDLKIAEEASGLELALIKSKILSKTTEIEQINAQLAIYDQRVELSGAGLARNEKLLKAGHTNQAQLDKVIEDHLALQSKRNDLLMKLNSTQSLLAELSNELELKPGIFKEKHNRLKRNLIENKQRITEVSSNIDYRIYAPLTGVIGSQLTHVGEFVRPGNTMVSLIPEGSKLQAELYVPATSIGFIKPEQEVSMRYSAFPYQHFGLHSGRVLSVSKVISLPEELETSVELTGAVYKVIVGLDSQSVSAQGEELTLGVGMELEASVKLENRSLVQWILEPIYSLRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES3</accession>
    <name>B1KES3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326418.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3829"/>
    <dbReference type="EnsemblBacteria" id="ACA88088">
        <property type="protein sequence ID" value="ACA88088"/>
        <property type="gene ID" value="Swoo_3829"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3829"/>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010403_1_0_6"/>
    <dbReference type="OMA" id="IELMEHT"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="708"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="940" mass="108024" checksum="0CBE6B047B31F480" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU2</accession>
    <name>B1KEU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326437.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3849"/>
    <dbReference type="EnsemblBacteria" id="ACA88107">
        <property type="protein sequence ID" value="ACA88107"/>
        <property type="gene ID" value="Swoo_3849"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3849"/>
    <dbReference type="eggNOG" id="COG1462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051487_0_0_6"/>
    <dbReference type="OMA" id="RILHEQC"/>
    <dbReference type="OrthoDB" id="1759778at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764767" evidence="2">
        <location>
            <begin position="20"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="375" mass="41072" checksum="CBE9B0AEE1B13B0C" modified="2008-04-29" version="1" precursor="true">MGKFSVLLVALFASSSALAGIESIEVTGTGKTLPLAIDAALVSAVEQVSGVTVSSQRQSLDSSSRKSGEGTSFLRQRTGEMNFGTAGRATYRILSENCGGEKCKVRLLANIETNDDLERQKKLKGMNKNRRTIAVEPFVGAHSKEFSRAIEARLVQDRKFRVISDRKQPGVDYVLKGRVVEARTTKRVVDNSRTVELTGEHIDDVQVFYDSKVVVEYQLIDLVNNQIKWSAKVPTTSGRNNLSYLLELSSRKVFEQLKENIYPMLLIAAEDGSLVLNSGGSTVELGERFEVFAAGEKIIDPITKESLGFTESKIGIIKVIKVLPKMAYVELVEGSRDALYELPIVRKMAKSKASVKAKPKAAEAPVVKKSSGIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV0</accession>
    <name>B1KEV0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0806</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323448.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0806"/>
    <dbReference type="EnsemblBacteria" id="ACA85101">
        <property type="protein sequence ID" value="ACA85101"/>
        <property type="gene ID" value="Swoo_0806"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0806"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_605326_0_0_6"/>
    <dbReference type="OMA" id="LHSRYNM"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="189"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="298"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="442" mass="50199" checksum="5E905B32391BDC07" modified="2008-04-29" version="1" precursor="true">MKVTKRLKILLILGLMLTGGILFSLVSLNDNQVRTNQELHQVIEIELKINELGTRLWLLFQYNDQDALIQTRYAHQDLKELLEQEQFNNESKNSIIANLIRMNLNIGSLIELSQKDIESKFQPSITTSAGMLSARYNMTLQSMNEDLTKLQKLAMRDAELSQRKILYAVVIFLTLGSVLVLILIIMTLRTFKANLNVLTLGIKDLEKGNLGSRLLVSDTDELSELAEQFNLMKHSLETTTIKKEQLQEEVDRQTEELQKQRADFQLLANYDSLTQLYSRSAFESQMKTAIARCGRTKLNGALLFIDLDRFKPINDNYGHSVGDIVLMHVSKMLTQAVRTSDIIARIGGDEFVIWLEPIENARQVTKVIEKLHLSLSTPFKYGDISVSVSASIGVSFYPLDATDLSGLLRVADDNMYKAKATPDTYYYFTPEANRRFSITKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEY0</accession>
    <name>B1KEY0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323478.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0836"/>
    <dbReference type="EnsemblBacteria" id="ACA85131">
        <property type="protein sequence ID" value="ACA85131"/>
        <property type="gene ID" value="Swoo_0836"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0836"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064910_0_0_6"/>
    <dbReference type="OrthoDB" id="1917125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="26949" checksum="FE83A206D5433F34" modified="2008-04-29" version="1">MLELFLLPETWVIFATLFALEVVLGVDNVVFISVLCERLPKEQRKLARNLGISLAVVARIGLVFSIAWIMSLTKPLIGLGEVSFTGSDLIMIFGGFFLLAKSLKELWSWLTESETNHSTYARTGLMVVLLQIVAVDAVFSMDSVITAVGLTSEVPIMVAAILSSAVVMILVAGRINNLITDHPGFKTLALLFLVLLGGLLMAEGFDIHVNKGYVYFAMAFGLIIELCHLQLKRKQRLTVKGLAPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF39</accession>
    <name>B1KF39_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0896</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thioredoxin family. DsbC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323537.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0896"/>
    <dbReference type="EnsemblBacteria" id="ACA85190">
        <property type="protein sequence ID" value="ACA85190"/>
        <property type="gene ID" value="Swoo_0896"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0896"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083593_0_0_6"/>
    <dbReference type="OMA" id="QMIVYKA"/>
    <dbReference type="OrthoDB" id="1678187at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03020">
        <property type="entry name" value="DsbA_DsbC_DsbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033954">
        <property type="entry name" value="DiS-bond_Isoase_DsbC/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018950">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009094">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10411">
        <property type="entry name" value="DsbC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54423">
        <property type="entry name" value="SSF54423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6 7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010004211" description="Thiol:disulfide interchange protein" evidence="7">
        <location>
            <begin position="22"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC_N" evidence="8">
        <location>
            <begin position="34"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="9">
        <location>
            <begin position="115"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="242" mass="26507" checksum="72E458B55A6864B2" modified="2008-04-29" version="1" precursor="true">MIFTRVCTLIFAVLLAQSAIAAPNTPTDDSKALKEKLADTLSVKVHSLQESPIPGLYEALTDRGVLYISKDGSKLFHGNLYDLDKGMKNLTEAAMAGPRIEMMKPLEDNMLVYKAKNEKHVVTVFTDTTCGYCRKLHNEMQEYNDLGITIRYLAFPRRGIPSANADEMESIWCAADPLQAMTDAKGGKSVKQEKCDAKIAEQYNLGQSFGVNGTPAIVLEDGSMIPGYQPPAALLKVLEATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF74</accession>
    <name>B1KF74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Homogentisate 1,2-dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324957.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2336"/>
    <dbReference type="EnsemblBacteria" id="ACA86615">
        <property type="protein sequence ID" value="ACA86615"/>
        <property type="gene ID" value="Swoo_2336"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2336"/>
    <dbReference type="eggNOG" id="COG3508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027174_0_0_6"/>
    <dbReference type="OMA" id="FMFETRW"/>
    <dbReference type="OrthoDB" id="193687at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006570">
        <property type="term" value="P:tyrosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="PTHR11056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01015">
        <property type="entry name" value="hmgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="430" mass="47929" checksum="1BBEED398E69982D" modified="2008-04-29" version="1">MALDLEYMTGFGNEFETEALPGALPKGQFSPQKVKYDLYAEQFNVTAFTAPRSDNRRNWFYRIRPSVVQGEYEAIDNGLVRTAPITEVITPPTMLRWDPVAIPETKTDFIDGLVTMAANGSANGQTGIGIHIYVANSSMEGRYFYNADGEMLFVPQDGKIVLHTECGKLAIEAGEIAVIPRGIKFSVELLTETARGYICENYGHSYVLAERGPVGANGYANDRDFQYPVAAFEDKEGDFELVAKFNGNLFRCDIGHSPFDVVAWTGNSAPYKYDLARFNVINTVSFDHPDPSIFTVLTSPSGTPGVANIDFVVFPPRWMVAENTFRPPYYHRNIMSEFMGLIEGVYDAKEHGFVPGGSSLHNCMSPHGPEAEVFEKASNAELAPQRYENTLAFMFESRYIISPTKYALEGTERQPNYSACWKGIEKKFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF97</accession>
    <name>B1KF97_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2359</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324980.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2359"/>
    <dbReference type="EnsemblBacteria" id="ACA86638">
        <property type="protein sequence ID" value="ACA86638"/>
        <property type="gene ID" value="Swoo_2359"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2359"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_15_0_6"/>
    <dbReference type="OMA" id="SGQYSWI"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766525" evidence="7">
        <location>
            <begin position="23"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="57"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="135"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="426" mass="43302" checksum="4215D9DA25E8507A" modified="2008-04-29" version="1" precursor="true">MKFKMKYLAASMLILGSSSVVAGNSDGKLDVIVKLNSDLAISGHQANKSNAKNLAAGMGVGAVKYAYGSAFFGFSASVTQGRLDALRNNPNVASIEFDGIKTINKGKPGGGNPPAAQTMPWGIARTGADANSNEGAGVHVYVLDTGLDSDHPDLAANISNSMAFEQCKGRSCSHPWDDDHGHGTHVGGTIGALNNDIDVVGMASQVTLHAAKICSSRGSCPNSSTIAALDWVTSEVQARGEAAVVNMSIGGSGNVTGSCTNSGFTGNDSYHEAICNARNAGVVVVVAAGNDSDNAANYTPAGYSDTVITVSSAKEGDDWNSFSNWGAQSASWTTNNSAPVAIAAPGGSVLSLRAGGGTTTMSGTSMASPHVAGAAALFLASNPQQANGTAFENTRAQLLQSAESTNNFSNTTGDPHSEDFLDASNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFF4</accession>
    <name>B1KFF4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3871</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3871"/>
    <dbReference type="EnsemblBacteria" id="ACA88129">
        <property type="protein sequence ID" value="ACA88129"/>
        <property type="gene ID" value="Swoo_3871"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3871"/>
    <dbReference type="eggNOG" id="COG1757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043525_0_0_6"/>
    <dbReference type="OMA" id="AMCMIYL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="38"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="47261" checksum="8F0609DC798BC9FB" modified="2008-04-29" version="1">MTTSKQTSPSHDVSPQNTAPTASFLALVPLFLFLALFIGAGLYFQSQGVDFAFYQLPSVVAILPAIIFALIISKQKLNQSIETFIAGIGHANIIAMCLIYLLAGAFAAVAKATGGVDATVALGLSLVPSNLLLPGFFVIAAFIATAMGTSMGTIAAVAPIALGIANEAQIELALMAGAVISGALFGDNLSIISDTTIAATRTQGCEMKDKFKENLIFAIPASIITLVLFTLAGQGQADVAAQEIDFIKVIPYLTILLLAVSGLNVFVVLTIGILLAGITGLLTMDYGVIQFGQDIYAGFGNMQEIFILSMLVGGLAALMQQQGGLAFVSKQIEKLIAKFSKAKGGASTRASELGMAGIVALTNTCVANNTVSIVVTGDIAKELALKHQVTPKRAASILDIFSCIIQGLIPYGAQALLIASVFSISPIEAVTHAWYCMILAVVAVSIVILRKRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFJ8</accession>
    <name>B1KFJ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PKD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326503.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3915"/>
    <dbReference type="EnsemblBacteria" id="ACA88173">
        <property type="protein sequence ID" value="ACA88173"/>
        <property type="gene ID" value="Swoo_3915"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3915"/>
    <dbReference type="eggNOG" id="COG1572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_387267_0_0_6"/>
    <dbReference type="OrthoDB" id="1293882at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00629">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767312" evidence="3">
        <location>
            <begin position="24"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="4">
        <location>
            <begin position="277"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="5">
        <location>
            <begin position="554"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="713" mass="79561" checksum="1F958BEDB6F64DC2" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ9</accession>
    <name>B1KFQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323572.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0932"/>
    <dbReference type="EnsemblBacteria" id="ACA85225">
        <property type="protein sequence ID" value="ACA85225"/>
        <property type="gene ID" value="Swoo_0932"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0932"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046133_0_0_6"/>
    <dbReference type="OMA" id="VKDYFFT"/>
    <dbReference type="OrthoDB" id="1223448at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764828" evidence="2">
        <location>
            <begin position="18"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="474" mass="51035" checksum="9D5FD7A5DB2A6F32" modified="2008-04-29" version="1" precursor="true">MARIILLLIAFCLGAFSAPMTLASTAATSTVENAQSWHYIDEKGELKVKLYFFWSKTCPHCAEAHPFIDSLPERYPWIELSSHMISAPGSMEKWQDIASQTGTKASSVPYMAMCENAVIGYSSEAVTGQYLVNQLKQCYQSLGGTLDPNDTFVASSAQGGDKPLFGTCSDGTAEDGNAGTCDLNTESQQTNTSSVQPVELPFLGVVAPEQLSLPLLTVVLAGVDAFNPCAFFVLLFLLSIMVNAKSRTRMLIVGGIFVFFSGFIYFLFMIAWLNIFELLGAGSDGGMIILGAGILALIAGVINIKDYFFTKGEVTLSMSAENRTGLIKRMGKLTSASSMAAMIAGTVVLSILANAYELLCTAGFPMIYTSVLAMHELPDLERYMYLAFYNIVYVIPLAIIVIAFSATLGKRKLTEKEGQTLKLMSGIMMIGLGGTLAMDPTALQNVALAIGLILSSILLTIVITITRKVLAKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT1</accession>
    <name>B1KFT1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0954</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323594.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0954"/>
    <dbReference type="EnsemblBacteria" id="ACA85247">
        <property type="protein sequence ID" value="ACA85247"/>
        <property type="gene ID" value="Swoo_0954"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0954"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_394261_0_0_6"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="438"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="699" mass="78621" checksum="9E90F03A53301C65" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT9</accession>
    <name>B1KFT9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M1 membrane alanine aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323602.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0962"/>
    <dbReference type="EnsemblBacteria" id="ACA85255">
        <property type="protein sequence ID" value="ACA85255"/>
        <property type="gene ID" value="Swoo_0962"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0962"/>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007335_1_1_6"/>
    <dbReference type="OrthoDB" id="771837at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERAP1_C" evidence="2">
        <location>
            <begin position="535"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="871" mass="98830" checksum="9C0634A07EC56C19" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW6</accession>
    <name>B1KFW6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323629.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85282">
        <property type="protein sequence ID" value="ACA85282"/>
        <property type="gene ID" value="Swoo_0989"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0989"/>
    <dbReference type="eggNOG" id="ENOG503039Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_192308_0_0_6"/>
    <dbReference type="OMA" id="DWLAIMA"/>
    <dbReference type="OrthoDB" id="1920504at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="87" mass="9644" checksum="4B40B405C8DB0A0D" modified="2008-04-29" version="1">MKNIPLQVNIEGQDSTVDTDWLAIMATLKKRGLSQSELSTIYQELSAGMRVTTRGLTLAEIKPSIALDGIIRETKFSENDYVGMIRA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG50</accession>
    <name>CRCB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">crcB</name>
        <name type="ordered locus">Swoo_2480</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325099.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG50"/>
    <dbReference type="SMR" id="B1KG50"/>
    <dbReference type="STRING" id="392500.Swoo_2480"/>
    <dbReference type="EnsemblBacteria" id="ACA86757">
        <property type="protein sequence ID" value="ACA86757"/>
        <property type="gene ID" value="Swoo_2480"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2480"/>
    <dbReference type="eggNOG" id="COG0239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114342_2_3_6"/>
    <dbReference type="OMA" id="EWRLFLI"/>
    <dbReference type="OrthoDB" id="1942863at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000125159" description="Putative fluoride ion transporter CrcB">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="4"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <sequence length="124" mass="13362" checksum="6021EA291E935BFC" modified="2008-04-29" version="1">MNNILFVALGGSIGAVFRYLISIFMVQLFGSAFPFGTLLVNIIGSFLMGVIYALGQVSEVSPEIKALVGVGLLGALTTFSTFSNETLLLIQSGAWLKAFLNIALNLCLCIFMVYLGQQLVFSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG74</accession>
    <name>B1KG74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NADH dehydrogenase (Quinone)</fullName>
            <ecNumber evidence="9">1.6.5.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3954</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.5.11" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326541.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3954"/>
    <dbReference type="EnsemblBacteria" id="ACA88211">
        <property type="protein sequence ID" value="ACA88211"/>
        <property type="gene ID" value="Swoo_3954"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3954"/>
    <dbReference type="eggNOG" id="COG0651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_9_3_6"/>
    <dbReference type="OMA" id="VEAAWKY"/>
    <dbReference type="OrthoDB" id="1887859at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="8">
        <location>
            <begin position="72"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="7">
        <location>
            <begin position="132"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="497" mass="53258" checksum="D42425919BB56E73" modified="2008-04-29" version="1" precursor="true">MNLSLALMLQLTILLPLLATFAIAVTGQKPNLREAVTISTSLAVLYCVVNLYQALNAGASISVSWWALMPGLEISFVVEPLGMLFALIASFLWLITTIYAIGYMRGHGEENQTRFYICFALAISAVMGLAFSANLFTLFIFYEVITLSTYPLVTHAGTEKAKQGGRVYLGILLSTSIAFFLLAIILTWFVSGSLEFKAGGVFDDNVNTTVAGAILVLFVFGIGKAAIMPFHRWLPAAMVAPTPVSALLHAVAVVKAGVFTVLKVCIFIFGLDLLPKLPTTEFLLYLAAISVLLASIVAMRQDNLKARLAYSTVSQLGYITIGALLATSSGVIGSSMHIASHAFGKITLFFCAGAILVASHKSKISEMRGLGFAMPITMAAFFIASLSIIGVPPAGGTWSKWFLLMGTVETGYWFIMVTLMLSSLLNIAYLLPIPYHAFFPGKDHPAASSGGIKEAPLPSLIALTITTLGCLTMFIYPQPFYELAKAILTVSGVSHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG99</accession>
    <name>B1KG99_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326566.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3979"/>
    <dbReference type="EnsemblBacteria" id="ACA88236">
        <property type="protein sequence ID" value="ACA88236"/>
        <property type="gene ID" value="Swoo_3979"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3979"/>
    <dbReference type="eggNOG" id="ENOG5032YD2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142731_0_0_6"/>
    <dbReference type="OMA" id="ATSKYIM"/>
    <dbReference type="OrthoDB" id="1732244at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021559">
        <property type="entry name" value="DUF3019"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11456">
        <property type="entry name" value="DUF3019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767330" evidence="1">
        <location>
            <begin position="22"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14651" checksum="24ECB5095A381F44" modified="2008-04-29" version="1" precursor="true">MDKLSLWLLLLCLITPLPALSQDSSIVFTATPERCVALHKGQTCYQDVLFQWQTPQVGSYCLVMSQSLHQLACWNGQAVQKYQYSFEGDSTTTFSLIRNDEAEPLAEVKVVVTWVYKAPKQSQSGWRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGD2</accession>
    <name>B1KGD2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326598.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4013"/>
    <dbReference type="EnsemblBacteria" id="ACA88269">
        <property type="protein sequence ID" value="ACA88269"/>
        <property type="gene ID" value="Swoo_4013"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4013"/>
    <dbReference type="eggNOG" id="COG4688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_377611_0_0_6"/>
    <dbReference type="OMA" id="CERIRTK"/>
    <dbReference type="OrthoDB" id="77366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="751" mass="87118" checksum="24293892C8C9AAA4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG3</accession>
    <name>B1KGG3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0998</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323638.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0998"/>
    <dbReference type="EnsemblBacteria" id="ACA85291">
        <property type="protein sequence ID" value="ACA85291"/>
        <property type="gene ID" value="Swoo_0998"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0998"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_6"/>
    <dbReference type="OMA" id="HFIILGP"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="342" mass="37508" checksum="692CA193ED1332D5" modified="2008-04-29" version="1">MSTLTISDVHSDYQGQQVLKGLDLTLKKGEIAALLGPSGCGKTTLLRAIAGLQTISQGEICINKRVLSGPNVFVPSEQRGVGMIFQDYALFPHLNVADNILFGVKGGTKDQRKRRLNEMLSLVKLDGLSQRFPHELSGGQQQRVSIARALAYEPELLLLDEPFSNIDAKVRGEMMLEIRAILKESNVSAVFVTHSKDEAFVFADKLALFNGGRIAQYGTAEELYSSPDDRYVAEFLGAGNYLQATVSSPTSVETALGTFKSSAELKHELNYKGELMLRPQQLEIVADEAGTGVILERRFLGNTCHYKVNVAEQSYEVNSQLSQLVPGQRVSLTTPVHSLVMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT6</accession>
    <name>B1KGT6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type VI secretion protein, EvpB/VC_A0108 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325146.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2528"/>
    <dbReference type="EnsemblBacteria" id="ACA86805">
        <property type="protein sequence ID" value="ACA86805"/>
        <property type="gene ID" value="Swoo_2528"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2528"/>
    <dbReference type="eggNOG" id="COG3517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018386_1_0_6"/>
    <dbReference type="OMA" id="MSHAPFL"/>
    <dbReference type="OrthoDB" id="683477at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010269">
        <property type="entry name" value="T6SS_TssC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044032">
        <property type="entry name" value="TssC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044031">
        <property type="entry name" value="TssC1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35565">
        <property type="entry name" value="PTHR35565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05943">
        <property type="entry name" value="VipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18945">
        <property type="entry name" value="VipB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03355">
        <property type="entry name" value="VI_chp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VipB" evidence="1">
        <location>
            <begin position="65"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="VipB_2" evidence="2">
        <location>
            <begin position="377"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="491" mass="55542" checksum="05BC1BF24AF57B4A" modified="2008-04-29" version="1">MESMETAQESSQVLNGNLLDEILAQTKITPIDEGYDVAKKGVAAFISNILETESNSEPINKALVDKMLVELDKKISSQMDQILHDESVQQMESSWRNLKLLVDRTDFRENIKIEVLHVTKSELLDDFEFAPETVQSGLYKHVYSSGYGQFGGEPIGAIVGNYAFTPSSQDMKLLQYVSAVGAMAHAPFLSSVGPEFFGIDSFEELPNLKDLKSTFESPKYTKWRSLRESEDARYLGLTAPRFLLRVPYDPIDNPIGSFNYRESVHASHEDYLWGNTAFALATRLTESFAKYRWCPNIIGPQSGGAVDDLPVHVFESMGALQSKIPTEVLITDRKEFELADEGFISLTMRKGSDNAAFFSANSIQKPKVFPNTKEGKEAETNYKLGTQIPYMMIINRLAHYIKVLQREQIGSWKERQDLERELNSWIKQFVADQENPPADVRSRRPLRAAKVEVMDVQGDPGWYQVSMAVRPHFKYMGANFELSLVGRLDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGZ9</accession>
    <name>B1KGZ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326640.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4055"/>
    <dbReference type="EnsemblBacteria" id="ACA88311">
        <property type="protein sequence ID" value="ACA88311"/>
        <property type="gene ID" value="Swoo_4055"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4055"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_0_0_6"/>
    <dbReference type="OMA" id="QHRIGMA"/>
    <dbReference type="OrthoDB" id="1064766at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="5"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="350" mass="38502" checksum="D43804D1957CA8BA" modified="2008-04-29" version="1">MTDNLFQTFALNETITLQNRILMAPLTRCMADEELVPTQAMADYYARRAEAGLIISEAVIIRPDGQGYPNTPGLFSSAQIDGWRVVTDAVHQGGGKIFAQLWHTGRVAHPHFFKKTGSTDVLAPSAVGVEGSVPRMRELSYQVPKAVTHEDIAQLVADYSQAASNAIDAGFDGVEIHGANGYLLDQFLHHDSNHRQDEYGQTPENMARFALEVVDAVAQRIGNERTALRVSPGAYFNMASDERDRAVFDYLLPQLELRNLAFLHIGIFDDAMKFDYLGGSASAYVRSVYNKTLVGVGSYSAESGSSAIAQDKFDLLAIGRPFIANPDYVSRVREGKELVEYSDEMLANLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHM7</accession>
    <name>B1KHM7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325252.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2635"/>
    <dbReference type="EnsemblBacteria" id="ACA86912">
        <property type="protein sequence ID" value="ACA86912"/>
        <property type="gene ID" value="Swoo_2635"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2635"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033198_1_0_6"/>
    <dbReference type="OMA" id="TMAFWVF"/>
    <dbReference type="OrthoDB" id="1217595at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="534" mass="57909" checksum="3699A9B76C624DA9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR5</accession>
    <name>B1KHR5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326722.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4137"/>
    <dbReference type="EnsemblBacteria" id="ACA88393">
        <property type="protein sequence ID" value="ACA88393"/>
        <property type="gene ID" value="Swoo_4137"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4137"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_44_6"/>
    <dbReference type="OMA" id="NDTSGHQ"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="412"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="554"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="826" mass="93174" checksum="17D8D0A6BE435F5F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ3</accession>
    <name>B1KHZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326799.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88471">
        <property type="protein sequence ID" value="ACA88471"/>
        <property type="gene ID" value="Swoo_4215"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4215"/>
    <dbReference type="eggNOG" id="ENOG5030W6R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2143725_0_0_6"/>
    <dbReference type="OMA" id="HRSGSFC"/>
    <dbReference type="OrthoDB" id="1771657at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="13615" checksum="1EED23553FCC21AF" modified="2008-04-29" version="1">MFFYITGLSVLIIILCAALYVIYRNMHSGRVKRAKEYNVLFDEDTVVDELITQLIEKNQHQENEDKTAQSKEDILATFIDLHRSGSFCAHLSEEEIIYFVKKKLNLESSTHGESSARD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI61</accession>
    <name>ACPS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="1">Holo-ACP synthase</shortName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">acpS</name>
        <name type="ordered locus">Swoo_1247</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323885.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI61"/>
    <dbReference type="SMR" id="B1KI61"/>
    <dbReference type="STRING" id="392500.Swoo_1247"/>
    <dbReference type="EnsemblBacteria" id="ACA85539">
        <property type="protein sequence ID" value="ACA85539"/>
        <property type="gene ID" value="Swoo_1247"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1247"/>
    <dbReference type="eggNOG" id="COG0736">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089696_3_1_6"/>
    <dbReference type="OMA" id="DERHYAV"/>
    <dbReference type="OrthoDB" id="1893660at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword id="KW-0276">Fatty acid metabolism</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000093918" description="Holo-[acyl-carrier-protein] synthase">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <sequence length="132" mass="13858" checksum="619F903468A4D9A8" modified="2008-04-29" version="1">MIVGLGTDIAEIERIEQKVPAAGDIKGLESCRLAKRVLTEPEMAIFIASKQPARYLAKRFAAKEAAAKALGTGIGRGVSFQHIEISNDTNGAPLISFNGGAADRLASLGGARAHISIADEKHYATATVILES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIJ6</accession>
    <name>B1KIJ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC</fullName>
            <ecNumber evidence="5 8">3.1.3.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">KDO 8-P phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4236</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + H2O = 3-deoxy-alpha-D-manno-oct-2-ulosonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11500"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="EC" id="3.1.3.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the KdsC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.45" evidence="5 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326819.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4236"/>
    <dbReference type="EnsemblBacteria" id="ACA88492">
        <property type="protein sequence ID" value="ACA88492"/>
        <property type="gene ID" value="Swoo_4236"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4236"/>
    <dbReference type="eggNOG" id="COG1778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106694_0_1_6"/>
    <dbReference type="OMA" id="VFMGVEN"/>
    <dbReference type="OrthoDB" id="1232828at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019143">
        <property type="term" value="F:3-deoxy-manno-octulosonate-8-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010023">
        <property type="entry name" value="KdsC_fam"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006118">
        <property type="entry name" value="KDO8-P_Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01138">
        <property type="entry name" value="C1.6.2:_Deoxy-d-mannose-octulo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01670">
        <property type="entry name" value="KdsC-phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006118-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006118-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20161" checksum="4E135D93BA7C588B" modified="2008-04-29" version="1">MSHQGFYGPIEDTVWQKASKIKLLICDVDGVFSDGLVYMSNTGDELKTFHTRDGYGVRSLLTSDIPVAIITGRKSKIVEDRMTALGITHIYQGVDDKLTPYQELLSLYKVTPEEVAYIGDDMVDLPVMKQVGLSVCVADGHPYVQQGADFVTHIKGGHGALRELTDLLLLSQNKFETAHGMSI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIT6</accession>
    <name>LSPA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="1">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Signal peptidase II</fullName>
            <shortName evidence="1">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lspA</name>
        <name type="ordered locus">Swoo_1292</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A8 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323930.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIT6"/>
    <dbReference type="SMR" id="B1KIT6"/>
    <dbReference type="STRING" id="392500.Swoo_1292"/>
    <dbReference type="MEROPS" id="A08.001"/>
    <dbReference type="EnsemblBacteria" id="ACA85584">
        <property type="protein sequence ID" value="ACA85584"/>
        <property type="gene ID" value="Swoo_1292"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1292"/>
    <dbReference type="eggNOG" id="COG0597">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083252_4_0_6"/>
    <dbReference type="OMA" id="NRWYFPA"/>
    <dbReference type="OrthoDB" id="1575081at2"/>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00855">
        <property type="entry name" value="SPASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0064">Aspartyl protease</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000097281" description="Lipoprotein signal peptidase">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <sequence length="176" mass="20500" checksum="C63DDC75F3C57E9A" modified="2008-04-29" version="1">MPTNWKDSGLRWYWMVVLVFIADQLSKQWVLANFELRESVELLPFFNFTYLRNYGAAFSFLSDAGGWQRWFFTFVAVGFSTLLTIWLRKQPRQMWRLNLAYTLVIGGALGNLIDRLQHGYVVDFLHFYWNTSHFPAFNIADSAICVGAALIIIDSIITERDDKKKKAQENNNTAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV2</accession>
    <name>B1KIV2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1308</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323946.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1308"/>
    <dbReference type="EnsemblBacteria" id="ACA85600">
        <property type="protein sequence ID" value="ACA85600"/>
        <property type="gene ID" value="Swoo_1308"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1308"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_936570_0_0_6"/>
    <dbReference type="OMA" id="CCGMTAG"/>
    <dbReference type="OrthoDB" id="1296029at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="32543" checksum="4598C60F76A1862C" modified="2008-04-29" version="1" precursor="true">MNLNKNKKITLISRPLFIFIVLATLWSTWLLQFPHPLELFGDYLHYLFLGITGAIFANSTGAGGGVIFIPVFNSLNFTNEQSISTSFVIQCFGMTAGALTWWLHFTHQKQAQQGRLLVKLIFICIPLSVAGIWTTHIFEIQAPGSLEHSFSLFSIALGLGIIYSCFALKNSDANHTLSRYEVLQLGFITYLGGIITAWLSVGVGEIIVIYLLLKKVTPSLAIAVGVIVTAFTVWSVSPIYLSEQSDAYFKVILFAGPGAIMGGILAKKLALYLPVKGLKIFFAGWIILSGVTMLVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIX6</accession>
    <name>B1KIX6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1332</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1332"/>
    <dbReference type="EnsemblBacteria" id="ACA85624">
        <property type="protein sequence ID" value="ACA85624"/>
        <property type="gene ID" value="Swoo_1332"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1332"/>
    <dbReference type="eggNOG" id="COG0325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059988_0_1_6"/>
    <dbReference type="OMA" id="IEWHMIG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="30"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="27151" checksum="1006CD2FFDCE91AB" modified="2008-04-29" version="1">MVYPLNQNNYMMTTIADRLADAQHRIIQAAQISSRNSDEIQLLAVSKTKPNTDIIAAYTAGQRHFGENYVQEGEAKVNALKSSCPEIHWHFIGPLQSNKSKIVASLFDWMHTLSREKIAQRLNEQRPDTLQPLNVCIQVNISQESSKSGATVDEVHSLASSISKLPKLKLRGLMAIPTATQDVLLQKAEFKKLQELYLNLQATYPDIDTLSMGMSNDLEQAIEHGSTMVRIGSAIFGERDISGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIZ7</accession>
    <name>B1KIZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323991.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85645">
        <property type="protein sequence ID" value="ACA85645"/>
        <property type="gene ID" value="Swoo_1353"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1353"/>
    <dbReference type="eggNOG" id="COG1607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050164_1_0_6"/>
    <dbReference type="OMA" id="RFHTRKW"/>
    <dbReference type="OrthoDB" id="1712258at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="122" mass="13558" checksum="CB76DDBF422FE039" modified="2008-04-29" version="1">MKYYSRRFIKPEHLNPANLLFGGQLLSWIDEEAAIFAGCQMKSQQLVTKLISEINFMTPARQGDVIEFGLELISAGSSSITVRCEVRSKVSHLPIVTINQMVFVNVDEKGLPKPHGIRANAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ01</accession>
    <name>B1KJ01_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1357</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell inner membrane</location>
            <topology evidence="2 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323995.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1357"/>
    <dbReference type="EnsemblBacteria" id="ACA85649">
        <property type="protein sequence ID" value="ACA85649"/>
        <property type="gene ID" value="Swoo_1357"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1357"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_1_6"/>
    <dbReference type="OMA" id="EMQWRER"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="869"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="894"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="922"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="966"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="999"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1040" mass="112279" checksum="0E8A1E0F6C1CB443" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ25</accession>
    <name>B1KJ25_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325381.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2769"/>
    <dbReference type="EnsemblBacteria" id="ACA87045">
        <property type="protein sequence ID" value="ACA87045"/>
        <property type="gene ID" value="Swoo_2769"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2769"/>
    <dbReference type="eggNOG" id="ENOG5031DNS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113723_0_0_6"/>
    <dbReference type="OMA" id="DWMYLMD"/>
    <dbReference type="OrthoDB" id="1530425at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024409">
        <property type="entry name" value="DUF3833"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12915">
        <property type="entry name" value="DUF3833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766699" evidence="1">
        <location>
            <begin position="27"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="20560" checksum="93E493787817C1B2" modified="2008-04-29" version="1" precursor="true">MSILFKRYLLTVFALCLAACSTPSLEDYKETTPELHLNEFFNGKLVAYGIVLDRSGKLLRRFKADIDANWQGDKGEIKEWFEFDDGESSTRVWQLTKEGESLYVGEAGDVVGRAYGETRGSALFWQYDLQIEVDGESLQVTLDDWMFLFDEQRLFNKTEMTKFGFKVGEVILYIEKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ95</accession>
    <name>B1KJ95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4314</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326894.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4314"/>
    <dbReference type="EnsemblBacteria" id="ACA88567">
        <property type="protein sequence ID" value="ACA88567"/>
        <property type="gene ID" value="Swoo_4314"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4314"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_0_6"/>
    <dbReference type="OMA" id="AQDQLSY"/>
    <dbReference type="OrthoDB" id="1200399at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767398" evidence="3">
        <location>
            <begin position="19"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="58"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="360" mass="39236" checksum="D497428428C55BE6" modified="2008-04-29" version="1" precursor="true">MTLLPKLLPLFITATMLAGCSTESVELTPETIRPVKLLEISDINAASMREFPAKVAATKQADLAFRVSGHLVDFSLVEGQSVKKGERLARLDDRDARNTLLNREAEYDLAEADYQRKGELLRRTLISQADYDLAKAQLKSAKAALANAQDQLSYTELKAPYAGTVAKISTDNYQMVQANQAILLLQKDRNIDVVIQVPESLASQVAQLNNKQGSQAKVVFANQPERSYPALLKEHATQVTTGTQSYEVVFTLPQPEDVKILPGMSAELKLDLSSTGELKTGAILPASAIMKRDEDGKNIVWLYQDDKGSVAPSVVTLGKVTTEGVEILNGVDAGDKVVVAGVQYLSADQLVKPLRWQRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJC4</accession>
    <name>B1KJC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GumN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326922.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4343"/>
    <dbReference type="EnsemblBacteria" id="ACA88596">
        <property type="protein sequence ID" value="ACA88596"/>
        <property type="gene ID" value="Swoo_4343"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4343"/>
    <dbReference type="eggNOG" id="COG3735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057525_0_0_6"/>
    <dbReference type="OMA" id="VYLELDM"/>
    <dbReference type="OrthoDB" id="1991552at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="294" mass="32746" checksum="2A33A9BDD893A706" modified="2008-04-29" version="1" precursor="true">MIATSQLKLILAVVWGACVGISFSVEASPEDRPPFYKIDYKGETSYLLGSIHIGKADFYPMAPQIESLFESAGSLVVEADTTNADINALINKYGIKSVPADIKTQAALESYCRPMERMCQAMSGFAPWLQSMQFGVVRFEALGYTANYGVEQRFISKNRDRPLLELESTEFQFSLMSSFDDTTQWKMVKETIEAPDDEMLALVDAWRSGDAKELNALMEGSMIDNGDVEMVEKILWHRNVGMAEKIGELMQDKQTIQPLFILVGAGHVVGPKSIVKELLKRGAKVKNCWELSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJS3</accession>
    <name>B1KJS3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1458"/>
    <dbReference type="EnsemblBacteria" id="ACA85746">
        <property type="protein sequence ID" value="ACA85746"/>
        <property type="gene ID" value="Swoo_1458"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1458"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_705757_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764973" evidence="2">
        <location>
            <begin position="31"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="391" mass="42870" checksum="17BD3D6872DBBB30" modified="2008-04-29" version="1" precursor="true">MKILTFTRFAINSFVAFVLSVASLSFQAEASQGQTVFIPIAVGDITTFIPIMPSSSTGSVTSTTTDGSYNLNWSAVTNASYYQIIITDEDGKKRIIKVFGTSYDLAGLSLGSNTIEVQACNANHQCGVGYLAGTVSRSSKVTYQHTDMLGTPVMETDVAGQVVSRSVYEPFGKRLGGEKTGIGYTGHLQDEDLGLTYMQARYYDPLIGRFYSNDPVGFTGEVDTFNRYSYVANNPYKYTDPNGQSKRRLRNQAKEARENNQIAEVAGEALVNILPEGAVKDFIQENVNVIKANNRRGALKKGQQHAQVPRKSKGGEDIPMNELNHSSRGKNYNKIKESGGTNLGRRDTNSKSSVMDHPDGHNDNNATHHESPHVHATNKKGDSIIIEYENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW5</accession>
    <name>B1KJW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium/pantothenate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2877</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325488.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2877"/>
    <dbReference type="EnsemblBacteria" id="ACA87152">
        <property type="protein sequence ID" value="ACA87152"/>
        <property type="gene ID" value="Swoo_2877"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2877"/>
    <dbReference type="eggNOG" id="COG4145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_1_6"/>
    <dbReference type="OMA" id="GWWGMRR"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015233">
        <property type="term" value="F:pantothenate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011849">
        <property type="entry name" value="Na/pantothenate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02119">
        <property type="entry name" value="panF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="481" mass="52347" checksum="6E3B353271B8432A" modified="2008-04-29" version="1">MTNLIPVLIYLVLSLVITRWWSSRQADVGQLHQDKAKRFFIGGFFLNGPMLALTLVATYTSASSFIGGPGAAYQMGLGWVWLALIQVPVAILTLGVLGPKFLAMRSAEHTTLIEWLDSRYQHPWLSSLAIVSLVMGFIAMIAVQFIGGARLFSGVSGISYEIGLGLFVLTVLGYTLTGGFRAVVLTDVLQGGVMLAGLILLFGSILSQGTLPELMEKVTAYSPQMLSPHGVNDYLGWPMMLSFWVLICFGTMGLPHTLVRLLAVKDSRSLMRGMVWGTIICFLMTLLPHLCGVFGRALYPELTVPDEIMPRLISGLFHPFWAGVLLAAPIAAVMSSVDSMLLQSAVSLIRDGVMKQYPRLSATRQIKLTRVAMLLITVLATYWAIEPPEMIVWINLAAFGALQAVFLWPIIAGVFWKNISGNSAFGAMGAGLISYLVFQLNAPLVWKIHPIVPALTISLLVMLLIHALSPQANVKALDGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ8</accession>
    <name>B1KJZ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anthranilate synthase component 1</fullName>
            <ecNumber evidence="5">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_2912</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325521.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2912"/>
    <dbReference type="EnsemblBacteria" id="ACA87185">
        <property type="protein sequence ID" value="ACA87185"/>
        <property type="gene ID" value="Swoo_2912"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2912"/>
    <dbReference type="eggNOG" id="COG0147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006493_9_4_6"/>
    <dbReference type="OMA" id="AYRSFMN"/>
    <dbReference type="OrthoDB" id="1786019at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005257">
        <property type="entry name" value="Anth_synth_I_TrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF22">
        <property type="entry name" value="PTHR11236:SF22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001373">
        <property type="entry name" value="TrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00565">
        <property type="entry name" value="trpE_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="10">
        <location>
            <begin position="17"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="9">
        <location>
            <begin position="245"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tryptophan binding" evidence="8">
        <location>
            <begin position="294"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Chorismate binding" evidence="8">
        <location>
            <begin position="331"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Chorismate binding" evidence="8">
        <location>
            <begin position="486"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="294"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="331"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>chorismate</name>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>chorismate</name>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>chorismate</name>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="486"/>
            <end position="488"/>
        </location>
        <ligand>
            <name>chorismate</name>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="501"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001373-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001373-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001373-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="519" mass="57138" checksum="528CD146C3024643" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK28</accession>
    <name>B1KK28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326985.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4407"/>
    <dbReference type="EnsemblBacteria" id="ACA88659">
        <property type="protein sequence ID" value="ACA88659"/>
        <property type="gene ID" value="Swoo_4407"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4407"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125322_0_0_6"/>
    <dbReference type="OMA" id="ACNGPCI"/>
    <dbReference type="OrthoDB" id="1862620at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="16692" checksum="AA643D95B1C21E97" modified="2008-04-29" version="1" precursor="true">MHRETGFTLVELVTTIILIAILSVVVLPRMLTNSSYSAFTLRDEFISELRKAQLLAMNNQGRCYRVAVDPQGYQLQRFSNLACTTVTAPTESKRQFEGGANLTLISSASSSFNVDFSGDSDGVSSLACSGACINVIADETLTISIESQGYIHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKA5</accession>
    <name>B1KKA5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327062.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4485"/>
    <dbReference type="EnsemblBacteria" id="ACA88736">
        <property type="protein sequence ID" value="ACA88736"/>
        <property type="gene ID" value="Swoo_4485"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4485"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_560070_0_0_6"/>
    <dbReference type="OMA" id="YREMGQL"/>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="279"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="520" mass="58744" checksum="D797F8D9DDEF6EFD" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI6</accession>
    <name>B1KKI6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1538"/>
    <dbReference type="EnsemblBacteria" id="ACA85826">
        <property type="protein sequence ID" value="ACA85826"/>
        <property type="gene ID" value="Swoo_1538"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1538"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087351_0_1_6"/>
    <dbReference type="OMA" id="HRSYQEK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="19637" checksum="1B0911214CE0E7FB" modified="2008-04-29" version="1">MCQRSMFSVIAYQAGYATSVSQLFHDAIHAIDEVHYSFEDKSAWSSKPRSAYHWHKRMSRSKAWLMIDKSMLIDGQPKCCGFINIETGFYTQGYIDSLYVHPAYQGKGIAKALYQTLEQWGVEQGYRELMVDASSLSKAMFLSQGFKLCHRSYQEKRGRVIMGYLMKKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN2</accession>
    <name>B1KKN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2978</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325585.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2978"/>
    <dbReference type="EnsemblBacteria" id="ACA87249">
        <property type="protein sequence ID" value="ACA87249"/>
        <property type="gene ID" value="Swoo_2978"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2978"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_10_6"/>
    <dbReference type="OMA" id="LMKAGPL"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="14"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="156"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="369" mass="41767" checksum="F051192CE0747670" modified="2008-04-29" version="1">MESSRDTFVKDKKTVLIVDDTPDNLSLLHELLKDNYHVKAAVNGVIALNIINKGGIDIILLDVMMPEMDGYEVCRRVKADDEICDIPIIFLTAKTSIDDETMGFDLGAADYLSKPISPPLLLARVKTHLEIKASKDYLKNQNILLENEVKRRTQEVVNIQNVTITAMANLAETRDPETGFHIKRTQIYMKLLATQLSHKEHYREMLTPAYIEQLFTSAPLHDIGKVGISDSILLKPGKLTKEEFDTMKTHAYLGFKSLDTAEKHMDQSDTFLHIAKDIAHYHHEKWDGSGYPDGLVGEAIPLSARMMAIADVYDALISKRVYKDAMTHETALDIIKEGKGNHFDPELIEAFLEVEDDFYEVASKYRDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP2</accession>
    <name>B1KKP2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325595.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2988"/>
    <dbReference type="EnsemblBacteria" id="ACA87259">
        <property type="protein sequence ID" value="ACA87259"/>
        <property type="gene ID" value="Swoo_2988"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2988"/>
    <dbReference type="eggNOG" id="ENOG5032E5X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1795162_0_0_6"/>
    <dbReference type="OMA" id="YANLCNE"/>
    <dbReference type="OrthoDB" id="1528399at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021422">
        <property type="entry name" value="DUF3069"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023132">
        <property type="entry name" value="Sama2622-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11269">
        <property type="entry name" value="DUF3069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158675">
        <property type="entry name" value="SSF158675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16321" checksum="55B2BC0932352A83" modified="2008-04-29" version="1">MIEITPEYKARVEQVSLNVCNLVIPMDQIPQNLFEAYANLCNELLEDSDEKFIKGWEALPNSAKALLPQEDFHGFYIANAWLQLSRVAQDISEAADTDDAIAENEYSGIFTRISDESLKESSKKLKKARTNRALLNSIRAVVDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKQ5</accession>
    <name>B1KKQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Redoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325608.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3001"/>
    <dbReference type="EnsemblBacteria" id="ACA87272">
        <property type="protein sequence ID" value="ACA87272"/>
        <property type="gene ID" value="Swoo_3001"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3001"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_11_2_6"/>
    <dbReference type="OMA" id="AINTSWS"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="32"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="196" mass="21953" checksum="95865956BE479268" modified="2008-04-29" version="1" precursor="true">MLKRVQQLHIQGLILIGMMTISGLLTVNAEPLTVETLAPDFSLSRIDGSQFNLSDFRGEKSVYLIFWNTWCGHCMKKVPKLVEIQSELGEQVELLAINTSWSDTLGEIEQFKARFNPNYAIAFDFDADITRRYGVIGTPTGFLIDINGVIKQIDGIAHTLAANLDLWNTIKPARDHRTFGVTCQEHTQGSHKETAC</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ4</accession>
    <name>LEU1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="1">2.3.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alpha-IPM synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Alpha-isopropylmalate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuA</name>
        <name type="ordered locus">Swoo_4550</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327126.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKZ4"/>
    <dbReference type="SMR" id="B1KKZ4"/>
    <dbReference type="STRING" id="392500.Swoo_4550"/>
    <dbReference type="EnsemblBacteria" id="ACA88800">
        <property type="protein sequence ID" value="ACA88800"/>
        <property type="gene ID" value="Swoo_4550"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4550"/>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022158_0_1_6"/>
    <dbReference type="OMA" id="NTMRMLV"/>
    <dbReference type="OrthoDB" id="840579at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword id="KW-0432">Leucine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000149294" description="2-isopropylmalate synthase">
        <location>
            <begin position="1"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01151"/>
        </source>
    </evidence>
    <sequence length="523" mass="56872" checksum="E748E505CF588B59" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL23</accession>
    <name>B1KL23_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiosulfate sulfurtransferase GlpE</fullName>
            <ecNumber evidence="1">2.8.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glpE</name>
        <name evidence="3" type="ordered locus">Swoo_0063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate</text>
            <dbReference type="Rhea" id="RHEA:16881"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:18022"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="EC" id="2.8.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GlpE family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322713.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0063"/>
    <dbReference type="EnsemblBacteria" id="ACA84364">
        <property type="protein sequence ID" value="ACA84364"/>
        <property type="gene ID" value="Swoo_0063"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0063"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_14_0_6"/>
    <dbReference type="OMA" id="VCYHGIS"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01444">
        <property type="entry name" value="GlpE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01009">
        <property type="entry name" value="Thiosulf_sulfurtr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023695">
        <property type="entry name" value="Thiosulf_sulfurTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="18"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="102" mass="11389" checksum="96C1023D20B3F2BC" modified="2008-04-29" version="1">MSTFQHLSVSQLIQLSETNPETQIVDIRDAASFESAHIKDSINLNNDNLANYIAEADMDQPLIVVCYHGISSQGAAQYMVEQGFDEVYSLDGGYQAWRESED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL64</accession>
    <name>B1KL64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0324 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322754.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84405">
        <property type="protein sequence ID" value="ACA84405"/>
        <property type="gene ID" value="Swoo_0104"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0104"/>
    <dbReference type="eggNOG" id="COG2855">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033541_2_0_6"/>
    <dbReference type="OMA" id="ARPPWFI"/>
    <dbReference type="OrthoDB" id="1856009at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018383">
        <property type="entry name" value="UPF0324_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106">
        <property type="entry name" value="PTHR30106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03601">
        <property type="entry name" value="Cons_hypoth698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="310" mass="32528" checksum="B3D485F383429ADA" modified="2008-04-29" version="1" precursor="true">MNTKTQNKIHVAIFVITGFLCLLPQISSPIALVLGFTLASLGLVPAHLDLATLTKKLLSYSIIGLGFGIHLQTAISVSLANLPLILGSIVFTLILGAVLTKALKFDTKTGHLISAGTAICGGSAIAAVSPAINAKSDQTAIALATIFILNSIALFLFPTLGHLLSMSQYDFGVWSAIAIHDTSSVVGAASAYGEEALVTATTIKLARALWIIPIALISAIIFGGDKKRITIPYFIGFYCLAIAIAHFFPQGEAAFEVIFALSKRVLVLCLFLIGAGITVKKMRAAGVKPLALGVILWLAIGVSSLLYILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB0</accession>
    <name>B1KLB0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer membrane protein assembly factor BamB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bamB</name>
        <name evidence="5" type="ordered locus">Swoo_1547</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BamB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324181.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1547"/>
    <dbReference type="EnsemblBacteria" id="ACA85835">
        <property type="protein sequence ID" value="ACA85835"/>
        <property type="gene ID" value="Swoo_1547"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1547"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027480_0_1_6"/>
    <dbReference type="OMA" id="GRVLWQR"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00923">
        <property type="entry name" value="OM_assembly_BamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017687">
        <property type="entry name" value="BamB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03300">
        <property type="entry name" value="assembly_YfgL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009007465" description="Outer membrane protein assembly factor BamB" evidence="4">
        <location>
            <begin position="25"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="395" mass="42699" checksum="771D3D5E41C78D39" modified="2008-04-29" version="1" precursor="true">MKSWCKTLLACGLSLGLLSACSSSDVEEEPVSPLPEIEASVFPTVSWSASVGNGVGPYYSRLRPAARYDKLYVADRYGQVVAFDEATGERAWERDFSSAFKDNILAKNKGAKLAAGVTAARDKVFIGGESGLLGALDAETGETEWSVVTGGELLSAPTVAEDIVVVNTSAGTLEAYSVEDGEQQWIYESKLPTLTLRGTGSANYEAGGFFVGTADGKIAVVIKNNGQAAWEQAIYTPKGGNEFTRMADVDMMPLIIGENLYAVSFNGNLVSMELRSGRVVWTRKYSSFHELADSGVNLFLVDDHSRIYAVDRRNGLENWSNTELANRDLTSAAVFKDYIVVGDFEGYLHFIDKSNGNIVGRVEVDSSGLFSQPLVVGDNIYVQTRNGKVARITLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLF6</accession>
    <name>B1KLF6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated CheW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324227.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1595"/>
    <dbReference type="EnsemblBacteria" id="ACA85881">
        <property type="protein sequence ID" value="ACA85881"/>
        <property type="gene ID" value="Swoo_1595"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1595"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048995_0_0_6"/>
    <dbReference type="OMA" id="RLEWNQV"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024181">
        <property type="entry name" value="Chemotax_regulator_CheV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002867">
        <property type="entry name" value="CheV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="3">
        <location>
            <begin position="19"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="180"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="307" mass="33990" checksum="D67F1F1401C173F8" modified="2008-04-29" version="1">MSSILESVNKRTQLVGANRLELLLFKLNGRQRFGINVFKVKEVLQCPPLTSLPKLSSFVKGVAHIRGATISVIDLSAATGGRPIEDIDGCFIIISEYNRSIQGFLVKSVERIINMNWEAIMPPPQGSGRYSYLTAVTEIEGELVEILDVEKILDEISPVKTEISQELSEQLTIDEDDNFHIMVIDDSAVARKQIIRALEALGLQIDTAIDGKDALNKLTKMAEEMDNVSKEIPLIISDIEMPEMDGYTLTAEIRDNPKLKDIKIVLHTSLSGVFNQAMVEKVGANDFIAKFNPDELAAAVNKHLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI1</accession>
    <name>B1KLI1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar assembly protein FliH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1620</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Needed for flagellar regrowth and assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324252.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1620"/>
    <dbReference type="EnsemblBacteria" id="ACA85906">
        <property type="protein sequence ID" value="ACA85906"/>
        <property type="gene ID" value="Swoo_1620"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1620"/>
    <dbReference type="eggNOG" id="COG1317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062625_0_0_6"/>
    <dbReference type="OMA" id="CIISSQR"/>
    <dbReference type="OrthoDB" id="1285795at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000563">
        <property type="entry name" value="Flag_FliH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01003">
        <property type="entry name" value="FLGFLIH"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="9">
        <location>
            <begin position="123"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="283"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="36264" checksum="9B56B57A20A84D02" modified="2008-04-29" version="1">MKSNKPEGESEVHPPEADIEFSHWHIPDVTTAVPEDVSNLFGRKAAQKPVTEEPDSILPPTLGQIEEIRQEAENEGFAQGKEEGHQAGLETGRLEGLKQGHDEGFEQGKEQGYQEGAEKALELIKRFEGLLEQFEKPLELLDNEIEQELVSLTLKLSRAVIGHEIKTHPEHILSALRQGVDSLPLKEQGVVIRLHPEDHELVGSLYSANQLEKNRWDLESDPSLTPGDCIILSQRSSVDMRLESRMSTVLQELESHQQNLSQTVEHQKQALDIASEASQVLETLPEEELNVETQQESDGEVTDESHHVENSKEQSPDDSPDKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK3</accession>
    <name>B1KLK3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CheW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324274.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1642"/>
    <dbReference type="EnsemblBacteria" id="ACA85928">
        <property type="protein sequence ID" value="ACA85928"/>
        <property type="gene ID" value="Swoo_1642"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1642"/>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062232_0_0_6"/>
    <dbReference type="OMA" id="RINHIMG"/>
    <dbReference type="OrthoDB" id="1711729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014506">
        <property type="entry name" value="UCP020479_CheW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020479">
        <property type="entry name" value="UCP020479_CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="191"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="338" mass="37692" checksum="0F66EC22683692D3" modified="2008-04-29" version="1">MSNSVDDAVLDYFSLLLEDDESGANTDLPVEAAKSQKPVQIVQKEIKSPVVKINAQEEKSDLADIDKFEALKKSVCEEALQIQKQAKLKAESFVNTKKQDPHLNKLALEQLLEPLFKPELKEATQEKVKDVAVVKTDSKLKSTSEAKKVKPEVQEQALDEQKQAVETKLETKTGEIPPKVTKDLLETLDDEFQVLFFKVAGLTLAVPLVSLGGIVKLDRLNHIMGRPSWYKGVQTHRDSQLNVVDTCAWVMPEKYDDALAESVNYQYVVLLEDSNWGLTCESLVNSVKIMKSDVNWRSRSGKRPWLAGVVKEQMCGILHVHSLIELLNSGLGSQDPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLR8</accession>
    <name>B1KLR8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3094</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325701.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3094"/>
    <dbReference type="EnsemblBacteria" id="ACA87365">
        <property type="protein sequence ID" value="ACA87365"/>
        <property type="gene ID" value="Swoo_3094"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3094"/>
    <dbReference type="eggNOG" id="COG0471">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005170_0_2_6"/>
    <dbReference type="OMA" id="LHGMNTY"/>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="464" mass="49952" checksum="618B450D593B7496" modified="2008-04-29" version="1">MSIEQTDDALIASTSDNAHRKKLLILFADILLFLLLYNFLPFDEGVNTGFSVLIFIAILWLTEAIHISITAILVPILAVTLGVFETKTAMSNFANPIIYLFFGGFVLAAALNHQGIDKLIAQKVLTASKGKLSLACMFLFGITALLSMWISNTATAAMMLPLALGILQQLDFKEHKSTYLFMLLGIAYSANIGGIGTLVGSPPNAIAAAQVGLSFSDWLEFGLITVALMLPSMLIALYLFLRPNLSVICELTKSDAKLNYQGKLTLLIFISTVCCWIFSKPLSQALGGIPQFDTIVALGAVVLLAGLGLVEWKKIERTTDWGVLILFGGGLTLSAILKATGTSVFLAHWVTDIFGNTHMALFTFAVIFFVIMLTEFASNTASAALLVPVFAAIAEALGLSPVMLSVLIGIAASCAFMLPVATPPNAIVYGSGFIKQSEMMRAGVIINFVSMFVLYIIAHTFWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS1</accession>
    <name>B1KLS1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325704.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3097"/>
    <dbReference type="EnsemblBacteria" id="ACA87368">
        <property type="protein sequence ID" value="ACA87368"/>
        <property type="gene ID" value="Swoo_3097"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3097"/>
    <dbReference type="eggNOG" id="COG3106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043657_0_0_6"/>
    <dbReference type="OMA" id="FDYPGEW"/>
    <dbReference type="OrthoDB" id="929462at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007413">
        <property type="entry name" value="DUF463_YcjX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38605">
        <property type="entry name" value="PTHR38605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04317">
        <property type="entry name" value="DUF463"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019381">
        <property type="entry name" value="YcjX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="484" mass="54409" checksum="59FAE060151DD4CF" modified="2008-04-29" version="1">MSRINRSFSKLSKKVSHTTKALAHRTSDRHIRLAVTGLSGAGKTAFITGLVDQLLNSGVIGESNQLPLWQVSREARLYGVKRDLQPDLTVASFDYEQAMSALRSSPPHWPASTRSISELRLAIRYQPEKGILAKLTDSATLYLDIVDYPGEWLLDLPMLKQTYRQWSVVQSQREQVLKSSSYYPAFSEALAGLNLSAKADEAELKQIAALYQQLLLDSVNNHGFYYAQPGRMLLPGELADAPVLAFFPLFGLSDSVLAEREKDDVDSAYHVLMKRFDEYKAKVITPFYKEYFAQFDRQILLVDCFTPLNRGKAQFDDMTQALNGIMESFKFGQSNLLKRLFSPRIDKLLFAASKVDHITRDQQGNVLSLLTQLVKQSQKQAKFEGCDVEVMAISAIKATKHAMVKSGSTEVEVVHGRALSTGEPVTLYPGEVPRNLPKSEFWDTQGFDFMQFAPPLIEAETEGADFSHIRLDHLLQYILGDKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLT2</accession>
    <name>B1KLT2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TOBE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325715.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3108"/>
    <dbReference type="EnsemblBacteria" id="ACA87379">
        <property type="protein sequence ID" value="ACA87379"/>
        <property type="gene ID" value="Swoo_3108"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3108"/>
    <dbReference type="eggNOG" id="COG3585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118993_1_1_6"/>
    <dbReference type="OMA" id="KMSIRNQ"/>
    <dbReference type="OrthoDB" id="2019258at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004606">
        <property type="entry name" value="Mop_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00638">
        <property type="entry name" value="Mop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51866">
        <property type="entry name" value="MOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mop" evidence="3">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="69" mass="7004" checksum="BE4DC28A94846FA0" modified="2008-04-29" version="1">MKISARNSLNGKIKSIAEGSVNNEVVIELAPGVEITSVVTKASCESLGLVVGGSAYAIIKASNVMVAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM28</accession>
    <name>B1KM28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c, class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4658</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327232.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4658"/>
    <dbReference type="EnsemblBacteria" id="ACA88908">
        <property type="protein sequence ID" value="ACA88908"/>
        <property type="gene ID" value="Swoo_4658"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4658"/>
    <dbReference type="eggNOG" id="COG3245">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082349_4_1_6"/>
    <dbReference type="OMA" id="KACQVCH"/>
    <dbReference type="OrthoDB" id="1469969at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002323">
        <property type="entry name" value="Cyt_CIE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40942">
        <property type="entry name" value="PTHR40942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00607">
        <property type="entry name" value="CYTCHROMECIE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767482" evidence="7">
        <location>
            <begin position="22"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="19"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="97" mass="10084" checksum="3D2C8707914ECD38" modified="2008-04-29" version="1" precursor="true">MKKLLAMTAVAALTLSASVSAQEGKAVYDKACQVCHSMGVAGAPKAHDAEAWAPRLAQGMDTLVSTIKTGKGAMPPGGMCTDCTDEDYKNAIDYMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM51</accession>
    <name>B1KM51_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chemotaxis protein methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0163</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="2.1.1.80"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.80" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0163"/>
    <dbReference type="EnsemblBacteria" id="ACA84464">
        <property type="protein sequence ID" value="ACA84464"/>
        <property type="gene ID" value="Swoo_0163"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0163"/>
    <dbReference type="eggNOG" id="COG1352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025854_0_0_6"/>
    <dbReference type="OMA" id="EWQEFVN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.155.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026024">
        <property type="entry name" value="Chemotaxis_MeTrfase_CheR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036804">
        <property type="entry name" value="CheR_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000410">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="192"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="209"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000410-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="280" mass="32861" checksum="99734D1E9FB31857" modified="2008-04-29" version="1">MTKADFEFIRSLAYENTGIVLPERKKHMVYSRLSRRLRQLNLKDFTQYCSFVSNTPDERIHFINALTTNLTAFFREGHHFDYLEQVVIPEWQRKSKKRLRVWSSACSTGEEPYSIAMTLEKHFPISQWDLKILATDLDTNVLEKASIGNYSRDSVTNLPARYLDKYVRHTADNQHIQMRSNIQKMIHFKQLNLLEKWPMNGPFDAIFCRNVLIYFDNETKQKIIAKFRKMLSPQGYLFIGHSETLVNISEEFDLIGQTIYRPLGHGGKKLAKPKFSAHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM62</accession>
    <name>B1KM62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0174"/>
    <dbReference type="EnsemblBacteria" id="ACA84475">
        <property type="protein sequence ID" value="ACA84475"/>
        <property type="gene ID" value="Swoo_0174"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0174"/>
    <dbReference type="eggNOG" id="ENOG5033ADG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162755_3_0_6"/>
    <dbReference type="OMA" id="NLFMAMR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021313">
        <property type="entry name" value="DUF2909"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11137">
        <property type="entry name" value="DUF2909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="72" mass="8105" checksum="34593ED8E48B4DC1" modified="2008-04-29" version="1" precursor="true">MNTLLVFKLVLVLLLLFILFNLARALFIMVKGESKVPMSQYLGRRVIFSVLVVVLLLLAMATGVITPNIRPY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM69</accession>
    <name>PLSB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycerol-3-phosphate acyltransferase</fullName>
            <shortName evidence="1">GPAT</shortName>
            <ecNumber evidence="1">2.3.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">plsB</name>
        <name type="ordered locus">Swoo_0181</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:15325"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="EC" id="2.3.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPAT/DAPAT family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322831.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KM69"/>
    <dbReference type="SMR" id="B1KM69"/>
    <dbReference type="STRING" id="392500.Swoo_0181"/>
    <dbReference type="EnsemblBacteria" id="ACA84482">
        <property type="protein sequence ID" value="ACA84482"/>
        <property type="gene ID" value="Swoo_0181"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0181"/>
    <dbReference type="eggNOG" id="COG2937">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015407_0_0_6"/>
    <dbReference type="OMA" id="EVIYVPC"/>
    <dbReference type="OrthoDB" id="580383at2"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00612"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102420">
        <property type="term" value="F:sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07993">
        <property type="entry name" value="LPLAT_DHAPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00393">
        <property type="entry name" value="Glyc3P_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041728">
        <property type="entry name" value="GPAT/DHAPAT_LPLAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028354">
        <property type="entry name" value="GPAT_PlsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="PTHR12563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500064">
        <property type="entry name" value="GPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000437">
        <property type="entry name" value="GPAT_DHAPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03703">
        <property type="entry name" value="plsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000123098" description="Glycerol-3-phosphate acyltransferase">
        <location>
            <begin position="1"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXXXXD motif">
        <location>
            <begin position="308"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00393"/>
        </source>
    </evidence>
    <sequence length="807" mass="91711" checksum="73609910422D31A8" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM89</accession>
    <name>B1KM89_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsY</name>
        <name evidence="10" type="ordered locus">Swoo_0201</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322851.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0201"/>
    <dbReference type="EnsemblBacteria" id="ACA84502">
        <property type="protein sequence ID" value="ACA84502"/>
        <property type="gene ID" value="Swoo_0201"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0201"/>
    <dbReference type="eggNOG" id="COG0552">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_0_0_6"/>
    <dbReference type="OMA" id="GIEATDY"/>
    <dbReference type="OrthoDB" id="656414at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54_N" evidence="9">
        <location>
            <begin position="188"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="282"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="283"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="41"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="290"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="372"/>
            <end position="376"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="436"/>
            <end position="439"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="491" mass="53762" checksum="278A878C873DB744" modified="2008-04-29" version="1">MAKKGFFSWFRKDKSQDEVQTQEVESVTESQEKARIEAEAVEQARIEAEAVEQARTEAEAVEQARIEVEAAEQARIEAEAVEQARIEAEAAEQARIEAEAVEQARIEAEAAEQARIEAEAAEQARIEAEAAEQARIEAEAAEQARNDAEAAEQTRIEAEAVEQAEVVTEERQPEPQEKPAKEGFFARLKRGLKRTSENIGSGFIGLFKGKKIDDDLFEELEEQLLIADVGVETTTRLISSLTEQASRKQLKDGEALYELLREEMQKTLEPASIPLVPENADGPFVILMVGVNGVGKTTTIGKLAKQYQAQGKSVMLAAGDTFRAAAVEQLQVWGQRNDIPVVAQHTGADSASVLFDALQAARARNVDVLIADTAGRLQNKSHLMDELKKVVRVMKKQDENAPHEVMLTLDASTGQNAISQAELFKQAVGVTGITISKLDGTAKGGVIFAIADKFGIPIRHIGVGEQIDDLRTFDAKDFIDALFTQEADEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMF3</accession>
    <name>B1KMF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transferase, hexapeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324297.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1665"/>
    <dbReference type="EnsemblBacteria" id="ACA85951">
        <property type="protein sequence ID" value="ACA85951"/>
        <property type="gene ID" value="Swoo_1665"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1665"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081811_1_2_6"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03360">
        <property type="entry name" value="LbH_AT_putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041561">
        <property type="entry name" value="PglD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020019">
        <property type="entry name" value="Sia_OAcTrfase_NeuD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17836">
        <property type="entry name" value="PglD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03570">
        <property type="entry name" value="NeuD_NnaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PglD_N" evidence="3">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="212" mass="22512" checksum="4AEAC20191585AE4" modified="2008-04-29" version="1">MNSPSLYIVGAGGLARELYSYLATNNFIYEGYELKGFLDDNQEALNGFNMVHKVLGPLKHHRIEANSLLLMGVASCQLKQDLFNFYRGLGASFITFSHSSSFVGRNVTIGEGSILGPNAVITTDVQIGLLSTINVNTSIGHDASLGDFCTLSGHCDVTGGVELGDRVFLGSHACIIPKVVIESDSIIGAGSVVIKRVVAGSTMFGNPAKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMS1</accession>
    <name>B1KMS1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3178"/>
    <dbReference type="EnsemblBacteria" id="ACA87449">
        <property type="protein sequence ID" value="ACA87449"/>
        <property type="gene ID" value="Swoo_3178"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3178"/>
    <dbReference type="eggNOG" id="ENOG50333PG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135651_0_0_6"/>
    <dbReference type="OMA" id="KCTQGTV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767502" evidence="1">
        <location>
            <begin position="23"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15194" checksum="7FF91F85BA619D45" modified="2008-04-29" version="1" precursor="true">MKNTILGICAVLLMAFSFQGVASTEWIKIADKTVNYKTETDTVTPRGSEKNVTHIKLKCTQGTVNLHKVVINMSDGTSKTLDNLGVLTKGLSSRSISIPKGDLKIKSIDLTYDSVGSQTLAIAGVSKKGKLDLLGKKPASKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV3</accession>
    <name>B1KMV3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325817.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3211"/>
    <dbReference type="EnsemblBacteria" id="ACA87481">
        <property type="protein sequence ID" value="ACA87481"/>
        <property type="gene ID" value="Swoo_3211"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3211"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_14_0_6"/>
    <dbReference type="OMA" id="RPAFPLM"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="33310" checksum="3BA8DADFD86E8EB3" modified="2008-04-29" version="1">MRFDDQVAVITGAGTGLGRAYALALAERGAKVALIDTSVSISEKRGRIDSPNLLSCHKAIEELGATACMFQLDVRDNQGVKCVIDEIVELWGHIDILINNAGVHRSCPFDNLTVEMWQEQLDVDLNGSFYMTKAVWSQMKHQGYGRVMMSCGVSALYGDMYEASYSASKMALIGLVNSLHMEGAEHDIKVNSLTPHALTSMTKDRLASSVKPLFSTSSITAAMLFLCSPGAPSGQHLLTAAGSVSHGQFTEFKPMYLDSDSCKPETLLSGWEQLHHAQPVNLHNSGEDQVLAWARRGASEHHISIE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMW8</accession>
    <name>RL6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplF</name>
        <name type="ordered locus">Swoo_4675</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327248.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMW8"/>
    <dbReference type="SMR" id="B1KMW8"/>
    <dbReference type="STRING" id="392500.Swoo_4675"/>
    <dbReference type="EnsemblBacteria" id="ACA88925">
        <property type="protein sequence ID" value="ACA88925"/>
        <property type="gene ID" value="Swoo_4675"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4675"/>
    <dbReference type="eggNOG" id="COG0097">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065464_1_2_6"/>
    <dbReference type="OMA" id="KPDPYKG"/>
    <dbReference type="OrthoDB" id="1398618at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000144049" description="50S ribosomal protein L6">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="176" mass="18750" checksum="927E3B998604D74C" modified="2008-04-29" version="1">MSRVAKAPVAIPAGVEVTLNEQTITVKGTKGSLTRVINTDVIVVVEDNEIKCSSVEGVKTNAQAGTARALINNMVVGVTEGFEKKLQLIGVGYRAKIAGNGVDLTLGFSHPLVHELPDGVSAVCPSQTEIVLTGTDKQLVGQVAAEIRGYRPPEPYKGKGVRYADEQVRRKEAKKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ8</accession>
    <name>COAA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pantothenate kinase</fullName>
            <ecNumber evidence="1">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">coaA</name>
        <name type="ordered locus">Swoo_4705</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic pantothenate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327273.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMZ8"/>
    <dbReference type="SMR" id="B1KMZ8"/>
    <dbReference type="STRING" id="392500.Swoo_4705"/>
    <dbReference type="EnsemblBacteria" id="ACA88955">
        <property type="protein sequence ID" value="ACA88955"/>
        <property type="gene ID" value="Swoo_4705"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4705"/>
    <dbReference type="eggNOG" id="COG1072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053818_1_1_6"/>
    <dbReference type="OMA" id="RKYTQVS"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02025">
        <property type="entry name" value="PanK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00215">
        <property type="entry name" value="Pantothen_kinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004566">
        <property type="entry name" value="PanK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285:SF139">
        <property type="entry name" value="PTHR10285:SF139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000545">
        <property type="entry name" value="Pantothenate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00554">
        <property type="entry name" value="panK_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000099951" description="Pantothenate kinase">
        <location>
            <begin position="1"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="95"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00215"/>
        </source>
    </evidence>
    <sequence length="316" mass="35941" checksum="8B2D3C4CDAD87ABE" modified="2008-04-29" version="1">MKSENQIHTALYLAFQRSQWAELRESVPLTLNEPELANLRGINEKLSLTEVTDIYLPLSRLLNLIVGAKQKRGLVLNEFLGRKPPKRPYIISIAGSVAVGKSTTARILQALLSQWPEHPRVDLVTTDGFLYPLAELKRRGLLQRKGFPESYDMKLLVEFISNIKAGAPYVEAPLYSHVSYDRITDDHQAIESPDILIIEGLNVLQTSQDAAVGTQQPFVSDFVDFSIYVDAQEQLLKKWYIDRFLQFRGGAFSDENSYFHHYSKLNDKEAKITAANIWDSINGPNLKLNIEPTRDRAHLILQKGDDHLMSQVLLRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNA4</accession>
    <name>YACG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA gyrase inhibitor YacG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yacG</name>
        <name type="ordered locus">Swoo_0300</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with GyrB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA gyrase inhibitor YacG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322950.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNA4"/>
    <dbReference type="SMR" id="B1KNA4"/>
    <dbReference type="STRING" id="392500.Swoo_0300"/>
    <dbReference type="EnsemblBacteria" id="ACA84601">
        <property type="protein sequence ID" value="ACA84601"/>
        <property type="gene ID" value="Swoo_0300"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0300"/>
    <dbReference type="eggNOG" id="COG3024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178280_1_0_6"/>
    <dbReference type="OMA" id="WAAEEHK"/>
    <dbReference type="OrthoDB" id="2071775at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008657">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00649">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005584">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36150">
        <property type="entry name" value="PTHR36150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03884">
        <property type="entry name" value="YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000130980" description="DNA gyrase inhibitor YacG">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00649"/>
        </source>
    </evidence>
    <sequence length="70" mass="8087" checksum="95CB7B5E144027B4" modified="2008-04-29" version="1">MPTSVKCPTCQKDVIWNNESKFKPFCCERCKLIDLGDWASEKHAIPVKPEFDADDLDNLGYDEADFFKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNC7</accession>
    <name>B1KNC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0323</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322973.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0323"/>
    <dbReference type="EnsemblBacteria" id="ACA84624">
        <property type="protein sequence ID" value="ACA84624"/>
        <property type="gene ID" value="Swoo_0323"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0323"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014750_1_0_6"/>
    <dbReference type="OMA" id="YSEFYQP"/>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766888" evidence="3">
        <location>
            <begin position="21"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="28"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="32"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="59"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="207"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="735" mass="81444" checksum="555ACBDF0222323B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNN3</accession>
    <name>B1KNN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325827.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3221"/>
    <dbReference type="EnsemblBacteria" id="ACA87491">
        <property type="protein sequence ID" value="ACA87491"/>
        <property type="gene ID" value="Swoo_3221"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3221"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_5_6"/>
    <dbReference type="OMA" id="YVFVMGR"/>
    <dbReference type="OrthoDB" id="141801at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="4">
        <location>
            <begin position="10"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="76"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="516"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="640" mass="70026" checksum="3BC6DDD077565106" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP3</accession>
    <name>B1KNP3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3231</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325837.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3231"/>
    <dbReference type="EnsemblBacteria" id="ACA87501">
        <property type="protein sequence ID" value="ACA87501"/>
        <property type="gene ID" value="Swoo_3231"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3231"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_11_2_6"/>
    <dbReference type="OMA" id="WASWCPF"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765079" evidence="3">
        <location>
            <begin position="20"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="20"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="17595" checksum="1C78CDD3D4B27336" modified="2008-04-29" version="1" precursor="true">MRLLKSALLFILFAGNLQAAEVLNVAPNFNLADPQGKMHTLAEYKGKPMIIHFWATWCPYCKKLQPGLESLRKEYANTDLQILGISFNEDEGAMPAETLKKRGIGFPTLINGESAAKSYGVPGTPTTVFINRGGEIVWVTNISDPNDPNLNAATEFILKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP5</accession>
    <name>B1KNP5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Thymidine kinase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tdk</name>
        <name evidence="12" type="ordered locus">Swoo_3233</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 8 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325839.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3233"/>
    <dbReference type="EnsemblBacteria" id="ACA87503">
        <property type="protein sequence ID" value="ACA87503"/>
        <property type="gene ID" value="Swoo_3233"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3233"/>
    <dbReference type="eggNOG" id="COG1435">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064400_2_1_6"/>
    <dbReference type="OMA" id="ENTVNHK"/>
    <dbReference type="OrthoDB" id="1279539at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="192" mass="21583" checksum="23F128604A4C51BC" modified="2008-04-29" version="1">MAQLYFYYSAMNAGKSTSLLQSSYNYRERGMNTLVMTASIDDRYGVGKVASRIGIETDAQVFGSDDNLAAMITSAHNEKQLHCILIDESQFLSKEQVKQLTHVVDNLDIPVLCYGLKTDFQGELFSGSQYLLAWADKLVELKTICHCGRKANMVLRLDGSGKPMRDGEQVAIGGNESYESVCRKHFREFLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP7</accession>
    <name>B1KNP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Electron transfer flavoprotein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3235</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325841.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3235"/>
    <dbReference type="EnsemblBacteria" id="ACA87505">
        <property type="protein sequence ID" value="ACA87505"/>
        <property type="gene ID" value="Swoo_3235"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3235"/>
    <dbReference type="eggNOG" id="COG2025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_0_6"/>
    <dbReference type="OMA" id="WRPYAEQ"/>
    <dbReference type="OrthoDB" id="1400253at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="6">
        <location>
            <begin position="3"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="307" mass="31525" checksum="D6C4F0FF6A868808" modified="2008-04-29" version="1">MAILVLAEHDNASLKLDTAKVVACASAIGGDIDILVAGHECGAVVEAAQKLSGVRQVLVADNGAYTHSLAENIAELIVNLASDYEHILAAASSHGKDAFPRVSALLDVAQLSEVVEVVSSDTFVRPVYAGSALATVQSLDDKKVMTVRTSAFDAVGADGAAAAVAIDKVFDSLSQFVSQTLTESERPELGAASVVVSGGRGMGSGENFSILEQLADKLGGALGASRAAVDAGFVPNDLQVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEVVPQLIESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ9</accession>
    <name>B1KNQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325853.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3247"/>
    <dbReference type="EnsemblBacteria" id="ACA87517">
        <property type="protein sequence ID" value="ACA87517"/>
        <property type="gene ID" value="Swoo_3247"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3247"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_996914_0_0_6"/>
    <dbReference type="OMA" id="HAAPMEG"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765085" evidence="1">
        <location>
            <begin position="19"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="14"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="28826" checksum="DD1549F210B6E5B8" modified="2008-04-29" version="1" precursor="true">MKFWLFLFFCFYSLAGNAVVKRHDIPPEDYVLNKIPAYLIDMPHEGHGVLINSQWVVTVAHTIFYDYIGKKLIVGSKGYEIESVHIHPDYTQPHKGLLKGDLAPLMSFFKSRSDIALIKLTSRGNDVEPINMYAGSSEKGKTITVYGRGATGNGLTGEDPDTKSLRVMNQFQNIVESAEGNWLVFKFDEPANALPLEGMHGSGDSGGAAVIFQQGVPYLIGLSSWQLGHGDIASFQGGLYGTTAYQVRVSNYQGWISSVLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNR2</accession>
    <name>B1KNR2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325856.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87520">
        <property type="protein sequence ID" value="ACA87520"/>
        <property type="gene ID" value="Swoo_3250"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3250"/>
    <dbReference type="eggNOG" id="ENOG5033BTC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179214_0_0_6"/>
    <dbReference type="OMA" id="DWARDEY"/>
    <dbReference type="OrthoDB" id="1950713at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="10721" checksum="C74CF59C111AD9C0" modified="2008-04-29" version="1">MSKLSTEQKALYSAIAKILWEKWDPIGVNDGDNEWDDEYDNYVPHIFRLALEGNDAIRIASSLTSTVEQIIGLGSDKESDLKVAKLIVQAKQEIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU7</accession>
    <name>B1KNU7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325891.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87555">
        <property type="protein sequence ID" value="ACA87555"/>
        <property type="gene ID" value="Swoo_3285"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3285"/>
    <dbReference type="eggNOG" id="ENOG50338YT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170386_0_0_6"/>
    <dbReference type="OMA" id="GESFHQF"/>
    <dbReference type="OrthoDB" id="1912121at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022193">
        <property type="entry name" value="DUF3718"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12514">
        <property type="entry name" value="DUF3718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765088" evidence="1">
        <location>
            <begin position="22"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12765" checksum="AD4B605B297DD0F7" modified="2008-04-29" version="1" precursor="true">MKKYLAIATLILTPLAFNASAAMHPQLEKTLVDVCKAGASNKMYQLRHTVKTNRINEKRIYPRLVCNGETFHQFALNQGADKTAKRIGKFMKGTVTIKDIAMTYGSDEILAVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY0</accession>
    <name>B1KNY0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Excinuclease ABC C subunit domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327328.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89011">
        <property type="protein sequence ID" value="ACA89011"/>
        <property type="gene ID" value="Swoo_4762"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4762"/>
    <dbReference type="eggNOG" id="COG2827">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135650_0_1_6"/>
    <dbReference type="OMA" id="RLYTGIT"/>
    <dbReference type="OrthoDB" id="1765072at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="14"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="95" mass="10937" checksum="143DA222F9FAEC07" modified="2008-04-29" version="1">MVIFVKEVVLVSESKWYLYMIECANGHLYTGVTVDIERRFSEHESGGPKAAKYLRGKGPLKLVYRELVGDRSGALKRELEIKSWSRKRKLALITH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA8</accession>
    <name>B1KPA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323027.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0379"/>
    <dbReference type="EnsemblBacteria" id="ACA84678">
        <property type="protein sequence ID" value="ACA84678"/>
        <property type="gene ID" value="Swoo_0379"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0379"/>
    <dbReference type="eggNOG" id="COG4775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034081_0_0_6"/>
    <dbReference type="OMA" id="NYLHINT"/>
    <dbReference type="OrthoDB" id="1463299at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764716" evidence="1">
        <location>
            <begin position="23"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="543" mass="62321" checksum="3A0F5A90A6D5D2CB" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH5</accession>
    <name>B1KPH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324474.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1844"/>
    <dbReference type="EnsemblBacteria" id="ACA86128">
        <property type="protein sequence ID" value="ACA86128"/>
        <property type="gene ID" value="Swoo_1844"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1844"/>
    <dbReference type="eggNOG" id="COG4088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083043_2_0_6"/>
    <dbReference type="OMA" id="GIFSTDS"/>
    <dbReference type="OrthoDB" id="1574819at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026302">
        <property type="entry name" value="NEDD4_b_p2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13308">
        <property type="entry name" value="PTHR13308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="18409" checksum="5C1FE53C0F9FF743" modified="2008-04-29" version="1">MPVNTYEAKPVVTNSTQGLAIIMRGLPGSGKSHWVNEFIARQAAEVRERFFTFGYFSTDSLFYRDDVYQFDVKRLSEFHQRNLTGFIQALSAGEPIVICDNTNLARWESMAYEAAAKALGFQVRYVLVGDPKDSAHQVMCAKRNSHGVPLSQIIKMANSFEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH7</accession>
    <name>B1KPH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1846</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324476.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1846"/>
    <dbReference type="EnsemblBacteria" id="ACA86130">
        <property type="protein sequence ID" value="ACA86130"/>
        <property type="gene ID" value="Swoo_1846"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1846"/>
    <dbReference type="eggNOG" id="COG4176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028473_1_0_6"/>
    <dbReference type="OMA" id="GDVFRHI"/>
    <dbReference type="OrthoDB" id="485527at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="102"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="32871" checksum="9253895B7DB9BC79" modified="2008-04-29" version="1">MADSWLSKFPKMDRADLLEIRKSLDGAFRDFSREYGDEIESFFSPLLDFLIWFEKLLVQSPWWAVLIVITAMVYLASRSWKLSLGVVVSFLLIGYFGMWEDTMRTLSIITVCTLLAIILGVPIGIFMARSDRTQSAVTPILDVMQTMPAFVYLIPVVMLLGIGKVPGVIAVVIYAIPPVIRLTNLGIRLVDKEVLEAATAYGANKMQRLLGVQLPLAAPTIMAGINQTIMMALGMVVIASMIGVKGLGQPVLKSITNQYFTLGLFNGLAIVALAIIFDRASQAYAKRSQKHLQDGHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW9</accession>
    <name>B1KPW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325987.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3384"/>
    <dbReference type="EnsemblBacteria" id="ACA87652">
        <property type="protein sequence ID" value="ACA87652"/>
        <property type="gene ID" value="Swoo_3384"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3384"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_397334_0_0_6"/>
    <dbReference type="OMA" id="HKANESQ"/>
    <dbReference type="OrthoDB" id="1289485at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="693" mass="79045" checksum="1789C3E2CBD52A36" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPY1</accession>
    <name>B1KPY1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Endonuclease I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3396</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EndA/NucM nuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325999.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3396"/>
    <dbReference type="EnsemblBacteria" id="ACA87664">
        <property type="protein sequence ID" value="ACA87664"/>
        <property type="gene ID" value="Swoo_3396"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3396"/>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037746_0_0_6"/>
    <dbReference type="OMA" id="EVDLVAW"/>
    <dbReference type="OrthoDB" id="1114630at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
        <property type="entry name" value="PTHR33607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04231">
        <property type="entry name" value="Endonuclease_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="SSF74853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764738" evidence="3">
        <location>
            <begin position="23"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="4">
        <location>
            <begin position="14"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="539" mass="57183" checksum="DC8A1C8FF731D856" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ13</accession>
    <name>B1KQ13_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <shortName evidence="8">BPG-independent PGAM</shortName>
            <shortName evidence="8">Phosphoglyceromutase</shortName>
            <shortName evidence="8">iPGM</shortName>
            <ecNumber evidence="8">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gpmI</name>
        <name evidence="14" type="ordered locus">Swoo_4877</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327443.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4877"/>
    <dbReference type="EnsemblBacteria" id="ACA89126">
        <property type="protein sequence ID" value="ACA89126"/>
        <property type="gene ID" value="Swoo_4877"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4877"/>
    <dbReference type="eggNOG" id="COG0696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026099_2_0_6"/>
    <dbReference type="OMA" id="FMDGRDT"/>
    <dbReference type="OrthoDB" id="338375at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="PTHR31637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="SSF64158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="12">
        <location>
            <begin position="8"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="iPGM_N" evidence="13">
        <location>
            <begin position="84"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="155"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="263"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8 9">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA89126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="514" mass="56059" checksum="C409756225194B33" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA7</accession>
    <name>B1KQA7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis accessory factor UbiK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiK</name>
        <name evidence="2" type="ordered locus">Swoo_0464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiK family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323111.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0464"/>
    <dbReference type="EnsemblBacteria" id="ACA84762">
        <property type="protein sequence ID" value="ACA84762"/>
        <property type="gene ID" value="Swoo_0464"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0464"/>
    <dbReference type="eggNOG" id="COG2960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154412_0_1_6"/>
    <dbReference type="OMA" id="KQPNDVF"/>
    <dbReference type="OrthoDB" id="1995361at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02216">
        <property type="entry name" value="UbiK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007475">
        <property type="entry name" value="UbiK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38040">
        <property type="entry name" value="PTHR38040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04380">
        <property type="entry name" value="BMFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="10174" checksum="7F19E8E896CB6053" modified="2008-04-29" version="1">MINPKKLEEVAKQLSDNLPNGLKQFAGEFEEKSKQILQNQLMKLDVVSHEEFEVQQHVLLKTREKLEALQAQVDALEKKLSEREESAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC6</accession>
    <name>HEM3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Porphobilinogen deaminase</fullName>
            <shortName evidence="1">PBG</shortName>
            <ecNumber evidence="1">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="1">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hemC</name>
        <name type="ordered locus">Swoo_0483</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="1">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323130.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQC6"/>
    <dbReference type="SMR" id="B1KQC6"/>
    <dbReference type="STRING" id="392500.Swoo_0483"/>
    <dbReference type="EnsemblBacteria" id="ACA84781">
        <property type="protein sequence ID" value="ACA84781"/>
        <property type="gene ID" value="Swoo_0483"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0483"/>
    <dbReference type="eggNOG" id="COG0181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019704_0_2_6"/>
    <dbReference type="OMA" id="LWQANHI"/>
    <dbReference type="OrthoDB" id="1450400at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000114178" description="Porphobilinogen deaminase">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="1">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <sequence length="309" mass="33459" checksum="3E106F08F8CD525C" modified="2008-04-29" version="1">MSQNVIRIATRKSPLALWQAEFVKAELEKFHPDLTVELLPMSTKGDIILDTPLAKVGGKGLFVKELEVAMLENRADIAVHSMKDVPVDFPEGLGLEIICEREDPRDAFVSNNYKSISELPKGAVVGTSSLRRQCQIRAARPDLQIRDLRGNVGTRLGKLDAGTYDAIILAAAGLKRLKLEERITSFISAEESLPANGQGAVGIECRTDDERVKALLAPLEHAETRFRVIAERAMNTHLEGGCQVPIGAYAEIVDDTLTLRGLVGNPDGTQIIASTKVGPKTDAKALGISLAEELLSKGAKTILDAVYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQV3</accession>
    <name>B1KQV3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326044.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3441"/>
    <dbReference type="EnsemblBacteria" id="ACA87709">
        <property type="protein sequence ID" value="ACA87709"/>
        <property type="gene ID" value="Swoo_3441"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3441"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111226_4_1_6"/>
    <dbReference type="OMA" id="IEICYNP"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="141" mass="16387" checksum="7CD669DB6F950F22" modified="2008-04-29" version="1">MEVLLQPVTRKNYEQVCELEVSKEQEALVAENTWSLVESLFEGYESRAIYANKELVGFFMWVHETSEKTSIWRFMIDQKFQNKGIGRKALDLALNEIKQSTKLREIEICYNPKNPVAKDFYSSFGFTEVGMDEDMLAVINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQX0</accession>
    <name>B1KQX0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP nucleosidase</fullName>
            <ecNumber evidence="2">3.2.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">AMP nucleosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3459</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + H2O = adenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:20129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.2.2.4"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.2.2.4" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326061.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3459"/>
    <dbReference type="EnsemblBacteria" id="ACA87726">
        <property type="protein sequence ID" value="ACA87726"/>
        <property type="gene ID" value="Swoo_3459"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3459"/>
    <dbReference type="eggNOG" id="COG1611">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047550_0_0_6"/>
    <dbReference type="OMA" id="EYKYTKK"/>
    <dbReference type="OrthoDB" id="424615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021826">
        <property type="entry name" value="DUF3412"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037153">
        <property type="entry name" value="YgdH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027820">
        <property type="entry name" value="YgdH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11892">
        <property type="entry name" value="DUF3412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14793">
        <property type="entry name" value="DUF4478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4478" evidence="5">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3412" evidence="4">
        <location>
            <begin position="329"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="450" mass="50276" checksum="D867E26B5C520CE2" modified="2008-04-29" version="1">MIVNVSPRGSMDQLSQLEVDRLKQNATSELYQLYRSCSLAVLASGLHSDNAENLFEQFSDFNINVLRRERGIKIELINPPEAAFVDGKIIVGIQEHLFAVLRDIVYLSDKYDNLKNINLTNPSHITNVVFDILRNAQVIPLEDPSIVVCWGGHSINDTEFHYTQDVGYELGLREMNICTGCGPGAMEGPMKGGTIGHAKQRISNARYIGLTEPSIIAAEPPNQIVNELVILPDIEKRLEAFVRLGHGIVIFPGGAGTAEELLYLLGILLNKENQDIPFPLILTGPKESADYFMRIDEFIAATLGEEAQSKYEIIIDDPVRVARVMSHGMDVVKDHRKSSGDSYQYNWSLKIEPEFQLPFNPTHEMMGDLNLHFQSDKAELAANLRRAFSGIVAGNVKMETIKSVMKNGPFQIKGDPTLMALMDKLLKAFVKQQRMKLPGSKYVPCYKINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR20</accession>
    <name>B1KR20_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Omp85 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0541</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323185.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0541"/>
    <dbReference type="EnsemblBacteria" id="ACA84837">
        <property type="protein sequence ID" value="ACA84837"/>
        <property type="gene ID" value="Swoo_0541"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0541"/>
    <dbReference type="eggNOG" id="COG2831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046092_0_0_6"/>
    <dbReference type="OMA" id="QVEYRLP"/>
    <dbReference type="OrthoDB" id="364966at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005336185" description="Omp85 domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="5">
        <location>
            <begin position="138"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="43477" checksum="2746AF5CAFEA6983" modified="2008-04-29" version="1" precursor="true">MKRILLLTLFAFSNAAIAVEPLFETPKDMEPTWVDDILSVFGADGEFDESKAIDMSYLPTAYYTPEKKFGVGLLMVGLYKTDGASAQEQPSSLVLNSFVSMNNSYGVEVENMTFFNGGKQRLLLELELHNEASVYYGQGIEQGHLDSNHHEFEEQLYSFKPRWMTEVADNYFVGVGANFVYASADKFQLAETEVPVDSSTILPDNVSSGVVVTSIYDSRDYRLNATKGWLFQIDAGLYQNSEYASFSTYDLELANYIDLSSTSILSSAPGLIAWQLQGHFTDGDVPWNMLPDLGGSNAMRGYIKGRYRDEQMMMGQVEYRLPIFQRYGMVFWGAAGSVAPKIGDLTDELLTSYGTGFRFKIKDNINLRLDVGVGENETNFYLNVNEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRB2</accession>
    <name>B1KRB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase with PAS/PAC sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324665.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2035"/>
    <dbReference type="EnsemblBacteria" id="ACA86319">
        <property type="protein sequence ID" value="ACA86319"/>
        <property type="gene ID" value="Swoo_2035"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2035"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_605327_0_0_6"/>
    <dbReference type="OMA" id="IGVEYKR"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="320"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="468" mass="53000" checksum="53E1E33EA2B1E4E3" modified="2008-04-29" version="1">MTDIEEALALLAAPCTDERFFQRALKALALVTQCRWAAFGRPSDVAGKAEVVAFCDLKHTVPGFEFDLEGSPCELIYRQKYPDTHLLFAKDLQTKFPNFQLIKDLGANSYQAELILDDGGNPIGHILVMDPLPQTETMKSKEFFRLLAQRIGVEYKRLLISRELALHKQMIAVTEHLMSFVDDSYTYHVVSKGYESLFNKSSREIVGKSVEQVHGKEVFNDVLKPLLDRTLKGETVQTRVWIHPPHTTPQYMNILHNPYFNEKGNIVGVIVSAHNITDMHAANEKIQQLANHDPLTGMLNRRALFEVMEGKLREQEQAKLQLAVLYIDLDGFQQINDRYGHHQGDKVLRYVASKIKDTAIDSEIVARIGGDEFIVLASFPHGNTYEHYQLKLEDLCDRLNSQLFIDIDIEGQSLPLSASIGHCLVNDATMELSAIISKADKDMYRNKRNERLGLVSMATGFIRQTPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD6</accession>
    <name>B1KRD6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324688.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2059"/>
    <dbReference type="EnsemblBacteria" id="ACA86343">
        <property type="protein sequence ID" value="ACA86343"/>
        <property type="gene ID" value="Swoo_2059"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2059"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_0_0_6"/>
    <dbReference type="OMA" id="YELTTIM"/>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="309" mass="33574" checksum="1CA8FDF00E01A068" modified="2008-04-29" version="1">MTTIADKPDYSLYSNAFGYLRQPLDFNPLKSDADVVVLGLPFDMATTGRSGGRMGPGAIRQASVNLAWEETRWPWNFKLSDHLSIVDAGDLVYDCGDSADFTQRVEDFATAILASGKAMLSFGGDHFVTLPLLRAHYKTHGKMALLHFDAHTDTYSQGSKYDHGTMFFHAPNEGIIDADHSIQIGIRTEYNRDDHAFKVIDAATANDLSADEIVAQIIERIGDLPLYITFDIDCLDPAFAPGTGTPVCGGITSDKAMKIIRGLAGVNVVGMDVVEVAPAYDNAEITALAGATLGLEMLHVWAESNKRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH7</accession>
    <name>B1KRH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ethanolamine transproter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324729.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2100"/>
    <dbReference type="EnsemblBacteria" id="ACA86384">
        <property type="protein sequence ID" value="ACA86384"/>
        <property type="gene ID" value="Swoo_2100"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2100"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_5_0_6"/>
    <dbReference type="OMA" id="RDRHLPH"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004757">
        <property type="entry name" value="EtNH_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00908">
        <property type="entry name" value="2A0305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="486" mass="51680" checksum="EBF10312A7685F00" modified="2008-04-29" version="1">MSQESKQQSAPKTKNKSIEYEAVSDEYMSQRQLKKGVAGWVLLASLGISYVISGDFAGWNFGLELGGFGGMLIATLVMGLMYICLVLSLAEMSSSLPTAGGGYSFARRAMGPWGGFLTGTAILLEYAIAPAAIAIFIGGYVNELVGIDGPIVYAAFYLVFVGLHLWGAGEALRIMMGITLLAVIAIGVFMVGMVPHFDPANLFDIAANPDVAGSSSFLPEGYMGIWAALPFAMWLFLAVEGVPLAAEEATDPAKDMPKGIIASMLVLIVFAAAVLLLVPGGAGAEAMKTHGAPLVGALQSVYGLDSLAAKFVNLVGLFGLIASFFSIIYAYSRQVFALSRAGYLPRFLSLSGQRKVPVWALIVPGILGFLLSLTGEGDLMITMAVFGATISYAMMSLSHILLRKKEPQLERPYKTPGGVLTSSIALILSLVALASTFVVSLQAAMWSALFYLIMVTYFVLYSRHRLVASAPEEEFDMIASAESELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRR3</accession>
    <name>B1KRR3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3564</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326161.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3564"/>
    <dbReference type="EnsemblBacteria" id="ACA87828">
        <property type="protein sequence ID" value="ACA87828"/>
        <property type="gene ID" value="Swoo_3564"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3564"/>
    <dbReference type="eggNOG" id="COG1314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094156_2_2_6"/>
    <dbReference type="OMA" id="MYEVLMV"/>
    <dbReference type="OrthoDB" id="2034545at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34182">
        <property type="entry name" value="PTHR34182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="11593" checksum="75FFA3A4B18CFDDE" modified="2008-04-29" version="1">MYEVLMVVYLLVAIGLVGLILIQQGKGADMGASFGAGASATLFGSSGAGNFLTRSTAILAIGFFALSLIIGNLSANHAKGEDAWQDLSSGAAQVTEQVTDAVETQKSEDKIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD21</accession>
    <name>B1KD21_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326189.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3592"/>
    <dbReference type="EnsemblBacteria" id="ACA87856">
        <property type="protein sequence ID" value="ACA87856"/>
        <property type="gene ID" value="Swoo_3592"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3592"/>
    <dbReference type="eggNOG" id="COG3655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_31_8_6"/>
    <dbReference type="OMA" id="ICKHLEC"/>
    <dbReference type="OrthoDB" id="2040098at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="68" mass="7578" checksum="FFB4A48213A36E9C" modified="2008-04-29" version="1">MKIVVNLDVMLAKRNMRLNDLSEKVGISIQNLSILKTGKAKAMRFSTLALICEALDCQPGDLLEYLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD67</accession>
    <name>B1KD67_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OmpA domain protein transmembrane region-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326235.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3640"/>
    <dbReference type="EnsemblBacteria" id="ACA87902">
        <property type="protein sequence ID" value="ACA87902"/>
        <property type="gene ID" value="Swoo_3640"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3640"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124465_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766466" evidence="1">
        <location>
            <begin position="25"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="12"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21072" checksum="459B0369601F8AF8" modified="2008-04-29" version="1" precursor="true">MIKSLSISLPLLASFLTFSQAANAGDSSHYIGGTLGYGFHEFETEKYGQASFSDSVTFDLYYRHMVNDNFGIEVGGMSGSGGAFSILSDIWNDVKGLSYRGLRTTAYARLPLGISNSLYAKAGTAYQWVDYNVRQDKETVSVSETDNGFYGAIGWEFRFRNGLALNAEYQHVPMSNLTLRSYNFGINYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD84</accession>
    <name>B1KD84_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326252.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3657"/>
    <dbReference type="EnsemblBacteria" id="ACA87919">
        <property type="protein sequence ID" value="ACA87919"/>
        <property type="gene ID" value="Swoo_3657"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3657"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_7_3_6"/>
    <dbReference type="OMA" id="YRYIRNY"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="212"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="494" mass="56402" checksum="607394FDD9F3ED15" modified="2008-04-29" version="1" precursor="true">MRIGIVIILLLFMVGCQATEGDKVSKEIAKQPNILWIYVEDMNDWMGAYGDKTVPTPNIDQLASQGVRFDKVIMPAAVCSAVRSAIISGEMQTTLGFHNHRSGRFDYNPIALPQGHKTVPELFRDNGYETFNIGKDDYNFHYDRSQLYSLHPGPIAGHQGAKNGPDFDWGKRLAQSGKPFFGQIQLRGGKYKVKNPPVKVDRASVTLPPYYNDQPLTRDAWARHYENIHLTDLDVGEIVKELKDNNLLENTIVFFFTDHGMGLLRHKQFLYDGGLQVPLVISWMNGNDKLRELGAERKELIRGLDIGGSSLGLAGIDIPAYMTTENFFAADYQAKPWVISARDRCDYTFEKMRSVRTDRFKYIRNYFPERPYMQAQYRDKWPLVKEYKKAFAAGEFNEIEAQLMAERKPAEELYDLDNDPHEVSNLAGVGAYKSQLTKMRGILNNWVKETGDKGQLPESDNGIREVLDFYHDKCQSPECQSYRTRHQLSGNKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDC5</accession>
    <name>B1KDC5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LmbE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323273.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0630"/>
    <dbReference type="EnsemblBacteria" id="ACA84926">
        <property type="protein sequence ID" value="ACA84926"/>
        <property type="gene ID" value="Swoo_0630"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0630"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_4_1_6"/>
    <dbReference type="OMA" id="HPDDETW"/>
    <dbReference type="OrthoDB" id="1380748at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="240" mass="26100" checksum="F0FE122B31705E94" modified="2008-04-29" version="1">MNKTEPVSSFSVIALFAHPDDETWISGTLATLAARGVQVTPVYVTSGDAGSDHSGQGLTGVELANVRESEARQATAILGLNSPIFLRFPDGKITQYEQEVKGKLTTLVKKNSPKIMLTFARGGITDNRDHKALNALVSEHFSTLAAYFAVSQSQAEILALSASKFDLNYRIARPVADADISIKPDVAGYQAQRVRAMASHKTQFPPVMIQAYQDYVEASPREALMGMSESQFIIFQTTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD1</accession>
    <name>B1KDD1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase DeaD</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cold-shock DEAD box protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">deaD</name>
        <name evidence="6" type="synonym">csdA</name>
        <name evidence="13" type="ordered locus">Swoo_0636</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323279.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0636"/>
    <dbReference type="EnsemblBacteria" id="ACA84932">
        <property type="protein sequence ID" value="ACA84932"/>
        <property type="gene ID" value="Swoo_0636"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0636"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_21_1_6"/>
    <dbReference type="OMA" id="LPQGMPK"/>
    <dbReference type="OrthoDB" id="626183at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070417">
        <property type="term" value="P:cellular response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12499">
        <property type="entry name" value="RRM_EcCsdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00964">
        <property type="entry name" value="DEAD_helicase_DeaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034415">
        <property type="entry name" value="CsdA_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028618">
        <property type="entry name" value="DEAD_helicase_DeaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="12">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="37"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="232"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="436"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="561"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="438"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="568"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA84932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="605" mass="67538" checksum="3321201ED7FB102F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD8</accession>
    <name>B1KDD8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Curli production assembly/transport component CsgG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in the biogenesis of curli organelles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CsgG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323286.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0643"/>
    <dbReference type="EnsemblBacteria" id="ACA84939">
        <property type="protein sequence ID" value="ACA84939"/>
        <property type="gene ID" value="Swoo_0643"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0643"/>
    <dbReference type="eggNOG" id="COG1462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056911_0_0_6"/>
    <dbReference type="OMA" id="GYWSQAQ"/>
    <dbReference type="OrthoDB" id="1013703at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005534">
        <property type="entry name" value="Curli_assmbl/transp-comp_CsgG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03783">
        <property type="entry name" value="CsgG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="255" mass="28137" checksum="46732C89E4701683" modified="2008-04-29" version="1">MKYLLPLVVIGLLSGCGLLPKPELNVSQAELNPVSETMLALQAKKGPKYPIPVAVYSFRDQTGQYKPQQNVSSFSTAVTQGATSMLIQTLLDSRWFTPVEREGLQNLLTERKITKKQPKSKDSEVPQLTNARLLLEGGIISYETNVSTGGIGMEYYGIGASELYREDQVTIYLRAVDVHSGKVMMSVSTTKRVFSQELRAGLFRFTSLNRLAEAEMGFTTNEPVQFCVLQAIELAVAEMVDKGIALGYWSPNSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDE7</accession>
    <name>B1KDE7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Galactokinase</fullName>
            <ecNumber evidence="11">2.7.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Galactose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">galK</name>
        <name evidence="15" type="ordered locus">Swoo_0652</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13553"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28061"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323295.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0652"/>
    <dbReference type="EnsemblBacteria" id="ACA84948">
        <property type="protein sequence ID" value="ACA84948"/>
        <property type="gene ID" value="Swoo_0652"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0652"/>
    <dbReference type="eggNOG" id="COG0153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_2_1_6"/>
    <dbReference type="OMA" id="NTHQDYK"/>
    <dbReference type="OrthoDB" id="1388391at2"/>
    <dbReference type="BRENDA" id="2.7.1.2">
        <property type="organism ID" value="12548"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00246">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022963">
        <property type="entry name" value="Galactokinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019741">
        <property type="entry name" value="Galactokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00106">
        <property type="entry name" value="GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="6 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalKase_gal_bdg" evidence="14">
        <location>
            <begin position="11"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_N" evidence="12">
        <location>
            <begin position="115"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="13">
        <location>
            <begin position="280"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="35"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="125"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA84948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="42186" checksum="94A931DB2863FAAD" modified="2008-04-29" version="1">MSNPAQRANKLFVQTFGTTADDLYLAPGRVNLIGEHTDYNDGFVLPAAINFHTIVAVKRREDAIFRVISDAFPGEIKEWEFGQEGQMDPQDTWINYLKGFTAAMAASGLPAKGLDLSIVGNVPLGAGLSSSAALEIAFGTAINDCSQLRLSPLAVAQMAQRGENQYVGYACGIMDQMISALGQQDHALLIDCEDLDSESVSIPESLSLIIVNSNVERGLLDPEFRLRRKQCESVAEHFGLDTLRHLDLCKLEAAKDKLDEVSYRRVKHVLTENRRTQNAAHALEAGNIPKLSQLMAQSHASMRDDFEITVPEIDTLVDIISGVVGERGGVRMTGSGFGGCVVALVDHELTDAVVEAIESQYTQQTGLEATVYLCSACDGAARVDEEFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDI4</accession>
    <name>B1KDI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0690"/>
    <dbReference type="EnsemblBacteria" id="ACA84985">
        <property type="protein sequence ID" value="ACA84985"/>
        <property type="gene ID" value="Swoo_0690"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0690"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_3_6"/>
    <dbReference type="OMA" id="FGCQALV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="43"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="224"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="469" mass="52315" checksum="1D4E5401532DF89E" modified="2008-04-29" version="1">MSQVTPNADSKMSFSTLTLKPELLDNLKTMGYDSMTPIQAQSLPAILNGEDVIGQGKTGSGKTAAFGLGLLHKLNVKRFRIQSLVLCPTRELADQVAKEIRTLARGIHNIKVLTLCGGVPMGPQIGSLEHGAHIIVGTPGRIIDHLSRERLSLEDVNTLVLDEADRMLEMGFLPDLDYIMAQMPRERQTLLFSATFPKQIQKIAEEIMYEPVMVKVTSTHDSNTIDQHFYELESNKDRQKALRLLLLQHRPESAVVFCNTKRETKDVAATLANDGFSVVALHGDLEQRDRDITLMQFANKSASIMVATDVAARGLDIEALDMVVNYEFAYDTEVHIHRIGRTGRAGSKGAAYTFYNYEDDYKVKLLEEYLDREITSEVLPPENLLDTFPTQPKMVTLQIDGGKKNKLRPGDILGGLTGEDGIQGSEVGKIKITDFRSYVAVDRKVAKRALHKITNGKLKGRSYRAWEMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDN3</accession>
    <name>B1KDN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324775.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2146"/>
    <dbReference type="EnsemblBacteria" id="ACA86430">
        <property type="protein sequence ID" value="ACA86430"/>
        <property type="gene ID" value="Swoo_2146"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2146"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_437360_0_0_6"/>
    <dbReference type="OMA" id="DKFFYFD"/>
    <dbReference type="OrthoDB" id="1353997at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022562">
        <property type="entry name" value="DUF3466"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11949">
        <property type="entry name" value="DUF3466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766480" evidence="1">
        <location>
            <begin position="26"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="637" mass="69899" checksum="5E9006043C0EA414" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ6</accession>
    <name>B1KDQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SirA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfur carrier protein TusA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324797.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2170"/>
    <dbReference type="EnsemblBacteria" id="ACA86453">
        <property type="protein sequence ID" value="ACA86453"/>
        <property type="gene ID" value="Swoo_2170"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2170"/>
    <dbReference type="eggNOG" id="COG0425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165255_3_1_6"/>
    <dbReference type="OMA" id="WRCPEPL"/>
    <dbReference type="OrthoDB" id="2042068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0033" evidence="2">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="73" mass="8285" checksum="8837A8BBBCB0F118" modified="2008-04-29" version="1">MDFIDLTPFRCPLALVKVKLALKALQEGEELCISLSDTGSRQDVPRFLKKVGYDFSELTNDEDILTLKIRRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU1</accession>
    <name>B1KDU1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase IS204/IS1001/IS1096/IS1165 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2646</name>
        <name evidence="5" type="ordered locus">Swoo_3683</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908</strain>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325263.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2646"/>
    <dbReference type="EnsemblBacteria" id="ACA86923">
        <property type="protein sequence ID" value="ACA86923"/>
        <property type="gene ID" value="Swoo_2646"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87943">
        <property type="protein sequence ID" value="ACA87943"/>
        <property type="gene ID" value="Swoo_3683"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2646"/>
    <dbReference type="KEGG" id="swd:Swoo_3683"/>
    <dbReference type="eggNOG" id="COG3464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041900_0_1_6"/>
    <dbReference type="OMA" id="CPVHDHR"/>
    <dbReference type="OrthoDB" id="1128314at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032877">
        <property type="entry name" value="Transposase_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029261">
        <property type="entry name" value="Transposase_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13542">
        <property type="entry name" value="HTH_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14690">
        <property type="entry name" value="zf-ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-ISL3" evidence="3">
        <location>
            <begin position="44"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_Tnp_ISL3" evidence="2">
        <location>
            <begin position="92"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="156"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="407" mass="46970" checksum="B4FF1B5758A69163" modified="2008-04-29" version="1">MSDTLLYQKVLGLEVPWLVSNVQLDEELQRITVVVDYVHNGDLVCPVCQQAGRHYDSRPRTWRHLDTCQFETLIHSKVPRVHCPEHGYQTLQVPWAHESSRYTELLEMRVLKMLAMSTLNAVSKFFKLSWGAIDRIMERAVARGLAHRTTYSTEALLIDETAIKKGRDYVTVLSNSQGQVLAVADGRSKASFNACFEQLPSYTTSLTKTICMDMSPAYISAAKAAFPDAEKRIAFDHFHIAKLLTEAVNAIRRDEIYRLSPSMRQEAHRTRFFWLKRRHNLPAHSQERLNKLVPSLMDTALAWYFKEQARDIWYSNSVRGTKQRWLEWIALIKATNIKPLMSVAETVESKLWGILNAMRFGVSNGLAEAINSQIRLLRVKAMGYRNTERFKRAILFHFGKLDMEFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV8</accession>
    <name>B1KDV8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="9">ALP N-acyltransferase</shortName>
            <ecNumber evidence="9">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lnt</name>
        <name evidence="11" type="ordered locus">Swoo_3700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326292.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3700"/>
    <dbReference type="EnsemblBacteria" id="ACA87960">
        <property type="protein sequence ID" value="ACA87960"/>
        <property type="gene ID" value="Swoo_3700"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3700"/>
    <dbReference type="eggNOG" id="COG0815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019563_3_0_6"/>
    <dbReference type="OMA" id="IPQSMKW"/>
    <dbReference type="OrthoDB" id="1291198at2"/>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="228"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="515" mass="57078" checksum="430C58C9C212442C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE07</accession>
    <name>B1KE07_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Extracytoplasmic solute receptor protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">TRAP transporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3750</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Part of the tripartite ATP-independent periplasmic (TRAP) transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326341.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3750"/>
    <dbReference type="EnsemblBacteria" id="ACA88009">
        <property type="protein sequence ID" value="ACA88009"/>
        <property type="gene ID" value="Swoo_3750"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3750"/>
    <dbReference type="eggNOG" id="COG4663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_0_1_6"/>
    <dbReference type="OMA" id="MRINQAW"/>
    <dbReference type="OrthoDB" id="1251304at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031317">
        <property type="term" value="C:tripartite ATP-independent periplasmic transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026289">
        <property type="entry name" value="SBP_TakP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039026">
        <property type="entry name" value="SiaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766981" description="Extracytoplasmic solute receptor protein" evidence="5">
        <location>
            <begin position="24"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR039026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR039026-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR039026-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="355" mass="40399" checksum="E79EF51AFC3FBB68" modified="2008-04-29" version="1" precursor="true">MFKHLSTTLIISTLLLASSSSIADEKKTYRWRLAETWPKDFPVFGDTVKSMAQRVKEMSNGRLIISIDSKNKHKAPLGIFDMVRAGQYQMGHSASYYWKGKDLKTMFFTTRPFGMTATEQYAWFYYGGGMELMQEVYGPYGLLSFPGGNTGNQMGGWFRKEIKSVDDLQGLKMRIPGFAGEVISKLGASPVNIPAGELYTALERNTIDALEWVGPSLDLRMGFQKVAPFYYTGWHEPATELQFLVNEKAFNTLPNDLQAILTIAMRASAYDMYAQSMHENAINLEKIAKEHPEIQIKTFPASIMLKLQQANNDLIEQFKQQDPLTKAIIESQERYQEITRPWTQISDQTYLEISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE51</accession>
    <name>B1KE51_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell surface receptor IPT/TIG domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323384.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0742"/>
    <dbReference type="EnsemblBacteria" id="ACA85037">
        <property type="protein sequence ID" value="ACA85037"/>
        <property type="gene ID" value="Swoo_0742"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0742"/>
    <dbReference type="eggNOG" id="COG4547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_252004_0_0_6"/>
    <dbReference type="OMA" id="ATYYIEF"/>
    <dbReference type="OrthoDB" id="107154at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764747" evidence="2">
        <location>
            <begin position="26"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1355" mass="148188" checksum="AC971746FCAA533A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEC1</accession>
    <name>B1KEC1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324843.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2217"/>
    <dbReference type="EnsemblBacteria" id="ACA86499">
        <property type="protein sequence ID" value="ACA86499"/>
        <property type="gene ID" value="Swoo_2217"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2217"/>
    <dbReference type="eggNOG" id="COG0432">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096980_0_2_6"/>
    <dbReference type="OMA" id="VRHTSCS"/>
    <dbReference type="OrthoDB" id="1691156at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="PTHR30615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="SSF111038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15640" checksum="8C5A283E3DAAF43B" modified="2008-04-29" version="1">MWIQKEFNLTSKPRGFHLITDEILNAIEEIASLQIGVLHIFIQHTSAALTLNENADPSVRVDFERYFNRLAPENEAYYTHTYEGPDDMPAHLKSSLLGASLTIPITNGTLNLGTWQGIYLCEARDRASSRHLIATIQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE4</accession>
    <name>B1KEE4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aldehyde-alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324865.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2241"/>
    <dbReference type="EnsemblBacteria" id="ACA86522">
        <property type="protein sequence ID" value="ACA86522"/>
        <property type="gene ID" value="Swoo_2241"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2241"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007207_2_1_6"/>
    <dbReference type="OMA" id="QWFKVPP"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008774">
        <property type="term" value="F:acetaldehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08178">
        <property type="entry name" value="AAD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034789">
        <property type="entry name" value="AAD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012079">
        <property type="entry name" value="Bifunc_Ald-ADH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000111">
        <property type="entry name" value="ALDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="4"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-ADH" evidence="4">
        <location>
            <begin position="457"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="866" mass="93175" checksum="330EEA5497CC929A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF7</accession>
    <name>B1KEF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2254</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324878.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2254"/>
    <dbReference type="EnsemblBacteria" id="ACA86535">
        <property type="protein sequence ID" value="ACA86535"/>
        <property type="gene ID" value="Swoo_2254"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2254"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_2_6"/>
    <dbReference type="OMA" id="RKAFEKW"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="27"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="506" mass="55187" checksum="5291DBDF58E0FDBB" modified="2008-04-29" version="1">MIYAYPGSDNSIVSFKAQYENFIGGKWVPPVKGVYFSNTTPVTGEEFCKIPRSCAQDIELALDAAHSAKEAWGNTSVQERSNILLKIADRIDENLEALAVAETWDNGKAVRETLAADLPLSSDHFRYYAGCIRAQEGTLSEIDKDTVAYHFHEPLGVVGQIIPWNFPLLMAAWKLAPALAAGNCIVLKPAEQTPASILLLMELIEDLLPAGVLNVVNGYGREAGEALATSTRIAKIAFTGSTAVGGHILKCAAENLIPSTVELGGKSPNIYFGDVTQHEDDYLDKCAEGFVLGFFNQGEVCTCPSRALVQEDIFDEFMAKVLQKTKEIIRGNPLDTTTMVGAQASQEQFDKIMGYLKIGNQEGAKVLTGGDQENLEDSLGNGFYVQPTILQGDNSMRIFQEEIFGPVIAVTTFKDEAEALAIANDSAYGLGAGVWTRDTNLAYRMGRGLQAGRVWTNCYHLYPAHAAFGGYKKSGIGRETHKMMLDHYQQTKNLLVSYSTSPLGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI1</accession>
    <name>B1KEI1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">2-oxoisovalerate dehydrogenase subunit alpha</fullName>
            <ecNumber evidence="4 9">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_2278</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + 3-methyl-2-oxobutanoate + H(+) = (R)-N(6)-(S(8)-2-methylpropanoyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10489"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the BCKDHA family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="4 9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324902.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2278"/>
    <dbReference type="EnsemblBacteria" id="ACA86559">
        <property type="protein sequence ID" value="ACA86559"/>
        <property type="gene ID" value="Swoo_2278"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2278"/>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_1_2_6"/>
    <dbReference type="OMA" id="GMFRGVN"/>
    <dbReference type="OrthoDB" id="1248201at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034616">
        <property type="entry name" value="BCKDH_E1-a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380:SF1">
        <property type="entry name" value="PTHR43380:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="E1_dh" evidence="10">
        <location>
            <begin position="55"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="43659" checksum="3CFF57D73E9840D6" modified="2008-04-29" version="1">MSNATSQNETVHRVSFLDRDSVNIPILKILQADGTVYENAVLPAIDEALAHKIYDTCVFTRVLDERMLGAQRQGRISFYMTCTGEEASIIGSAASLDNDDVILAQYREHAALRYRGFTTEQFMNQLFSNEKDLGKGRQMPIHYGSSELNYQTISSPLATQIPQATGVGYSLKMQGKRNIAICYFGEGAASEGDFHAGLNMAAVLKSPTIFFCRNNGYAISTPTSEQFMGNGIASRGPGYGMHTIRVDGNDMLAVLAATQQARAYAVENNAPVLIEAMTYRLGAHSSSDDPSGYRSKDEEAKWQQHDPVKRFKLWMINKGWLTEKQDSELFEKYRSEVLAEVKVAEKLPMSSVDTLIEDVYDTPTPRLKQQLETLKTHIKKYPKSYPNSEGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEK3</accession>
    <name>B1KEK3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2302</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324923.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2302"/>
    <dbReference type="EnsemblBacteria" id="ACA86581">
        <property type="protein sequence ID" value="ACA86581"/>
        <property type="gene ID" value="Swoo_2302"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2302"/>
    <dbReference type="eggNOG" id="COG0208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062403_0_0_6"/>
    <dbReference type="OMA" id="KVGEYQR"/>
    <dbReference type="OrthoDB" id="1384440at2"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="43583" checksum="35DA1283877B7103" modified="2008-04-29" version="1">MAYSTFCQTPNDARLEPMFLGQSVNVARYDVQKYEVFEKLIEKQLSFFWRPEEVDVSKDKIDYAALPDHEKHIFISNLKYQTLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPSIVFDDIVENEEILKRASDIAEYYDTLIKLTQAFHLLGEGTHMIDGRELIVTKREIKKALYLCMMSVNVLEAIRFYVSFACSFAFAERKVMEGNAKIIRLIARDEALHLNSTQHIIKLMQAGKDDPEMGEIAKECEQQAYDIFVKAAEQEKEWARYLFKDGSMIGLNEQILCQYVEYITNERMKSVNLDLPYAQITNPLPWMKTWLESDSVQVAPQEVEVSSYLVGQIDSSIDESEFEDFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN3</accession>
    <name>B1KEN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FMN-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3789"/>
    <dbReference type="EnsemblBacteria" id="ACA88048">
        <property type="protein sequence ID" value="ACA88048"/>
        <property type="gene ID" value="Swoo_3789"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3789"/>
    <dbReference type="eggNOG" id="COG4659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118052_0_0_6"/>
    <dbReference type="OMA" id="FFTDQFK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767291" evidence="1">
        <location>
            <begin position="23"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="2">
        <location>
            <begin position="87"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="20203" checksum="2370F6F40C30787B" modified="2008-04-29" version="1" precursor="true">MMKPLQTLIFIAASILSIAVLAKSQYQAPQDFISQAFNAPAPKAKVFWLDDEAQKVIEEILSHKFRKMRIRYWQQEGETVWILNEIGKEAPITVGIHIKDQQIAQTKVLIYRESRGDEVRHDFFTDQFKAAKLNEDLKLDRHIDGITGATLSVRALTKLSRIALWLDSRIRREIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN6</accession>
    <name>B1KEN6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Penicillin-binding protein 1B</fullName>
            <shortName evidence="13">PBP-1b</shortName>
            <shortName evidence="13">PBP1b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Murein polymerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Swoo_3792</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3792"/>
    <dbReference type="CAZy" id="GT51">
        <property type="family name" value="Glycosyltransferase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88051">
        <property type="protein sequence ID" value="ACA88051"/>
        <property type="gene ID" value="Swoo_3792"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3792"/>
    <dbReference type="eggNOG" id="COG0744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006354_2_7_6"/>
    <dbReference type="OMA" id="VHGMGLA"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009274">
        <property type="term" value="C:peptidoglycan-based cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011813">
        <property type="entry name" value="PBP_1b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028166">
        <property type="entry name" value="UB2H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14814">
        <property type="entry name" value="UB2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002799">
        <property type="entry name" value="PBP_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02071">
        <property type="entry name" value="PBP_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="13" id="KW-0133">Cell shape</keyword>
    <keyword evidence="13" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 13 20" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="UB2H" evidence="19">
        <location>
            <begin position="95"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="18">
        <location>
            <begin position="191"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="17">
        <location>
            <begin position="455"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for transglycosylase activity" evidence="14">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate; for transpeptidase activity" evidence="14">
        <location>
            <position position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002799-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACA88051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="790" mass="87067" checksum="3D32FDB77980A6C1" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ0</accession>
    <name>B1KEQ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3806</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326396.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3806"/>
    <dbReference type="EnsemblBacteria" id="ACA88065">
        <property type="protein sequence ID" value="ACA88065"/>
        <property type="gene ID" value="Swoo_3806"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3806"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_396321_0_0_6"/>
    <dbReference type="OrthoDB" id="822136at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="181"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="436"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="314"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="439"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="600" mass="68722" checksum="F43A9DD8D5A78756" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER2</accession>
    <name>B1KER2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="2 4">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="2 4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326408.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3818"/>
    <dbReference type="EnsemblBacteria" id="ACA88077">
        <property type="protein sequence ID" value="ACA88077"/>
        <property type="gene ID" value="Swoo_3818"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3818"/>
    <dbReference type="eggNOG" id="COG0634">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073615_0_0_6"/>
    <dbReference type="OMA" id="TMDWMAV"/>
    <dbReference type="OrthoDB" id="1819460at2"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="13"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="176" mass="20047" checksum="1DC43AFE454220F9" modified="2008-04-29" version="1">MKHTIEEMISVEEIDQKLDLLAEQINAHYADSERLLMVGLLKGSVVFMADLCRRIKGHVEIDFMSVSSYGNAMTSTREVKILKDVQSDIKGRDVLIVEDLIDSGNTLNKIREMLTLREPKSLALCTLLDKPERREIDVPVDFIGFTIPDEFIVGYGIDYAEQYRNLPYIAKVIPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET7</accession>
    <name>B1KET7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326432.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88102">
        <property type="protein sequence ID" value="ACA88102"/>
        <property type="gene ID" value="Swoo_3843"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3843"/>
    <dbReference type="HOGENOM" id="CLU_2036463_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="121" mass="13374" checksum="DED727D747067CD2" modified="2008-04-29" version="1">MDTKTTERSDKLRVNISLEAKRPSSEFANDLEAKRPSSELANVLEAKRPRSELANALEAKRPSSELANALEAKRPSSELANFLEAKRPRSELANALEAKRPSRAKPALLSPHSYWPIVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV4</accession>
    <name>B1KEV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323452.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0810"/>
    <dbReference type="EnsemblBacteria" id="ACA85105">
        <property type="protein sequence ID" value="ACA85105"/>
        <property type="gene ID" value="Swoo_0810"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0810"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_6"/>
    <dbReference type="OMA" id="LDEIWLI"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="288" mass="31012" checksum="2354320C6E18200B" modified="2008-04-29" version="1">MSHELHTDKAVEPLPTILITGASKGVGAACAHGFAKAYPAGVRLVLVARGLAALQALESDLVQYPNAQILTLTADIADLQACQTLVDQTLAKFGQINVLINNAGLHHRGAFAERTPEQIAAMIDLNLKSPLYLSSLVLPHMPSPAEGCCNAIVMVGSLAGRAPLQGAATYSSTKSGLRAFTYALHDELKESSINVAVVSPGPIDTSFIMDEIDEVEDIVYSQPMSTPEQVADAVIRLSQSQDAEIAMPWFSGKLATLGYLSPRFRQAIRGLLYKIGRKNKEKYRQRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX9</accession>
    <name>B1KEX9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85130">
        <property type="protein sequence ID" value="ACA85130"/>
        <property type="gene ID" value="Swoo_0835"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0835"/>
    <dbReference type="eggNOG" id="ENOG5031B8K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128258_1_0_6"/>
    <dbReference type="OMA" id="GHFYDYW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025294">
        <property type="entry name" value="DUF4156"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13698">
        <property type="entry name" value="DUF4156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="14846" checksum="38F98A817246BA18" modified="2008-04-29" version="1">MSDFFILATQLSMKLLSIAAGLIISISLSGCITFPTDHSNQVKVLWDDPETISQCEHKGTVIGSQGHFYDYWLHADRDMVWGTLNEMRIKAAKLGADTIYLYRPLGFTGSVTMMANAYQCGENKIESMHPPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF01</accession>
    <name>B1KF01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S metabolism associated SufE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323499.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0858"/>
    <dbReference type="EnsemblBacteria" id="ACA85152">
        <property type="protein sequence ID" value="ACA85152"/>
        <property type="gene ID" value="Swoo_0858"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0858"/>
    <dbReference type="eggNOG" id="COG2166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124502_1_0_6"/>
    <dbReference type="OMA" id="HYFLADS"/>
    <dbReference type="OrthoDB" id="1996347at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597">
        <property type="entry name" value="PTHR43597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufE" evidence="2">
        <location>
            <begin position="26"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="146" mass="16221" checksum="631DFF1F7BDA20DD" modified="2008-04-29" version="1">MSQVSQPSQETFLALKLDSSEILPLFEQASNWQERYRQIMLLGKALPKLDEAFRVESAQVRGCESSAWLYHSVIEDKHYFVADSDARIVKGLIGLLLTACQGKTSAEIARFDIEGYFDMLGLTGQLSPSRTNGLFALAKAIKAFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFB1</accession>
    <name>B1KFB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_2373</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324994.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2373"/>
    <dbReference type="MEROPS" id="S08.050"/>
    <dbReference type="EnsemblBacteria" id="ACA86652">
        <property type="protein sequence ID" value="ACA86652"/>
        <property type="gene ID" value="Swoo_2373"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2373"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_7_6"/>
    <dbReference type="OMA" id="AGKWYVM"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764793" evidence="7">
        <location>
            <begin position="23"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="10">
        <location>
            <begin position="42"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="156"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="PPC" evidence="9">
        <location>
            <begin position="439"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="PPC" evidence="9">
        <location>
            <begin position="548"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="628" mass="64900" checksum="1D1F490971374B13" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS4</accession>
    <name>B1KFS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323587.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0947"/>
    <dbReference type="EnsemblBacteria" id="ACA85240">
        <property type="protein sequence ID" value="ACA85240"/>
        <property type="gene ID" value="Swoo_0947"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0947"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_1_0_6"/>
    <dbReference type="OMA" id="WVDQDLQ"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25334" checksum="FF444973E8EB4BF9" modified="2008-04-29" version="1">MKESEAHHPLTDFIEYGEEEMLARAQIHYQEVKRRHSIRQFSDRAVPEAIIAQCIQTAATAPSGANHQPWHFVAISDPKVKAQIRHEAEALERSFYEGRAGEEWLDALKPLGTDANKSYLERAPWLIAVFSQKRGGMENDESKTNYYVHESVGIATGFLLQALHNAGLGTLTHTPKPMSFLSKVCGRDNDVDRPYMLIIAGYPDEGASIPDHATKKKSLDDICTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFX9</accession>
    <name>B1KFX9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325028.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2408"/>
    <dbReference type="EnsemblBacteria" id="ACA86686">
        <property type="protein sequence ID" value="ACA86686"/>
        <property type="gene ID" value="Swoo_2408"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2408"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_10_4_6"/>
    <dbReference type="OMA" id="PCLFHIR"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="63"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="548" mass="60900" checksum="2BD974967890B8B0" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY8</accession>
    <name>B1KFY8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2417</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325037.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2417"/>
    <dbReference type="EnsemblBacteria" id="ACA86695">
        <property type="protein sequence ID" value="ACA86695"/>
        <property type="gene ID" value="Swoo_2417"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2417"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_0_2_6"/>
    <dbReference type="OMA" id="AEVCVMP"/>
    <dbReference type="OrthoDB" id="1587662at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="29"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="163"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="249" mass="27651" checksum="DBF7A2EDABDCF052" modified="2008-04-29" version="1">MTDNNKSRRAAVPGCAIHCHDCSMGTLCIPFTLNATELDRLDEIIERKKPIQKGEQIFKSGDTLKSLFAIRSGTIKSFTITEQGDEQITGFHLAGDVIGFDGIHAQEHKSFAQALETSMVCEIPFSTLDDLSGTMPKLRQQIMRLMSNEIQSDQEMILLLSKKNAEERLAAFISNLATRFGSRGFSPKEFRLTMTRGDIGNYLGLTVETISRLLGRFQKAELIEVKGKYITIVNFDALNKLAGNSAIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG67</accession>
    <name>B1KG67_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326534.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3947"/>
    <dbReference type="EnsemblBacteria" id="ACA88204">
        <property type="protein sequence ID" value="ACA88204"/>
        <property type="gene ID" value="Swoo_3947"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3947"/>
    <dbReference type="eggNOG" id="ENOG5031E0T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1804881_0_0_6"/>
    <dbReference type="OMA" id="DRAYRTR"/>
    <dbReference type="OrthoDB" id="1853482at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767328" evidence="1">
        <location>
            <begin position="21"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="15873" checksum="0F24699C64C0CD3F" modified="2008-04-29" version="1" precursor="true">MKSSQILLVLTLVLPFSLLAAPTDLTNEERVVLESCTSLNNTTKELTAAPCVYYVRGFLAGSLSTKSTFIVRETSGEFLDRAYRTRVGKQTSEEQPIQLCLPKDKNIEQLTQRLIEHFSPPIESMEALHTQISDALGVELPCS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG89</accession>
    <name>GCST_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminomethyltransferase</fullName>
            <ecNumber evidence="1">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gcvT</name>
        <name type="ordered locus">Swoo_3969</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326556.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG89"/>
    <dbReference type="SMR" id="B1KG89"/>
    <dbReference type="STRING" id="392500.Swoo_3969"/>
    <dbReference type="EnsemblBacteria" id="ACA88226">
        <property type="protein sequence ID" value="ACA88226"/>
        <property type="gene ID" value="Swoo_3969"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3969"/>
    <dbReference type="eggNOG" id="COG0404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_10_2_6"/>
    <dbReference type="OMA" id="MPVQYPA"/>
    <dbReference type="OrthoDB" id="282830at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00259">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022903">
        <property type="entry name" value="GCS_T_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0032">Aminotransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000114117" description="Aminomethyltransferase">
        <location>
            <begin position="1"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00259"/>
        </source>
    </evidence>
    <sequence length="364" mass="39455" checksum="C8EDF9D5B11BDF75" modified="2008-04-29" version="1">MANKTVLFNKHLESDAKMVDFHGWDMPLNYGSQIEEHHAVRQDAGMFDVSHMTVVDVNGTDACAFLRKLLANDVAKLKVPGKALYGGMLDHNAGVIDDLITYYLNDTHYRIVVNSATREKDLAWIAQEVKGFDVVITERPELAMIAVQGPNAKAKAASVFNTAQNAAVEGMKPFFGVQADSLFIATTGYTGETGYEIIVPDSEAEALWLALLEAGVKPCGLGARDTLRLEAGMNLYGLDMDESVNPLAANMGWTIAWEPADRNFNGREALAAIKAAGTEKMVGLIMEAKGVIRPGMSVFFSDSDGVEQQGTITSGTFSPTLGYSIAMARVPRSIADTAEVEMRKKRVPVKVIAPSFVRNGKQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGJ5</accession>
    <name>B1KGJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323670.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1030"/>
    <dbReference type="EnsemblBacteria" id="ACA85323">
        <property type="protein sequence ID" value="ACA85323"/>
        <property type="gene ID" value="Swoo_1030"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1030"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="GYRFRQP"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="133"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="133"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="26892" checksum="4B28FC682D387B44" modified="2008-04-29" version="1">MTDPQSTHRVLLVEDDIRLANLIVDYLKSHGMHVEVERRGDTVLTRLINYKPDIILLDIMLPGMDGLTLCEKLPDYFAGPILLMSALGSNEDQIKGLELGADDYVVKPVDPALLIARINNLLRRTAKPPKVESHCLSFGKLSIDPHTQAIRLGDLEVDLTSHEFELLWLLASQAGQVLSRQYIYQYLLNIDFDGKDRKIDVRVSRLRKKLGDNIETPFRIKTVWGQGYLFAPEAWTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL5</accession>
    <name>B1KGL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GPR1/FUN34/yaaH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323689.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1050"/>
    <dbReference type="EnsemblBacteria" id="ACA85343">
        <property type="protein sequence ID" value="ACA85343"/>
        <property type="gene ID" value="Swoo_1050"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1050"/>
    <dbReference type="eggNOG" id="COG1584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051062_3_0_6"/>
    <dbReference type="OMA" id="WKKGNTF"/>
    <dbReference type="OrthoDB" id="1399490at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="21784" checksum="22FE99AEDC336619" modified="2008-04-29" version="1">MSTKLANPAPLGLMGFGMTTILLNIHNAGFFPIDSMILAMGIFYGGLGQVIVGCMCFKRGDTFGTTAFTSYGLFWLTLVGLLVMPKMGLTEASPAGFMGWYLTMWGIFTAFMFVGSLRYPRAKQVVFGSLTVLFFLLAARDFTGSALIGTIAGFEGILCGASAIYFAMAQVLNAEYGRTILPIGELAVEESKTVQIETQLKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN7</accession>
    <name>B1KGN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1072</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323711.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1072"/>
    <dbReference type="EnsemblBacteria" id="ACA85365">
        <property type="protein sequence ID" value="ACA85365"/>
        <property type="gene ID" value="Swoo_1072"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1072"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_6"/>
    <dbReference type="OMA" id="TRWRIEL"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="214"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="316" mass="35714" checksum="F6C3D9706DEF304D" modified="2008-04-29" version="1">MLKEGSHRLKKQDSTFDILDDVIATLRFRGSIFFHSDLAAPWGISLPPLPTPRFHIALHGDFVIGTSEAQLPIMQMDIVMLPKGDMHWIADETSSELVPCQLAGDACELGNPLFQEGEITNRIMCGMVEYDEAISHPILDALPSIFHFTHIEVDNPIWTTVRQIDSEIQRTNSQRSVIIDRLTEVLFFQLLHRYIAENEHLHGFLAALRNPRLAKVLQLLHDNPEKPWTLATICNEAGMSRASLQRKFKAELDLSPMAYLGSWRLAKAYQLVKNSSLTLDNIADRIGYADARTLRAAFKRHYGFSPSALRKGDSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH05</accession>
    <name>B1KH05_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326646.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4061"/>
    <dbReference type="EnsemblBacteria" id="ACA88317">
        <property type="protein sequence ID" value="ACA88317"/>
        <property type="gene ID" value="Swoo_4061"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4061"/>
    <dbReference type="eggNOG" id="ENOG5032UYY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1721093_0_0_6"/>
    <dbReference type="OMA" id="NVCKGHN"/>
    <dbReference type="OrthoDB" id="1576889at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="155" mass="15394" checksum="B43BC20BE9C99F5F" modified="2008-04-29" version="1" precursor="true">MNTKAQATLTGAALALTMAGLTGCASTEKSETTQAAMAKGSTDLVHCYGVNVCKGHNDCKTATNACGGHASCKGTGFVAMPSKSCADVGGKIQDDWVGSIAKTDLVHCYSVNVCKGHNDCKTANNACGGHASCKGTGFVSAPAKSCADIGGKVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHA1</accession>
    <name>B1KHA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1116</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1116"/>
    <dbReference type="EnsemblBacteria" id="ACA85409">
        <property type="protein sequence ID" value="ACA85409"/>
        <property type="gene ID" value="Swoo_1116"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1116"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_1_6"/>
    <dbReference type="OMA" id="VAMKKPQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046942">
        <property type="term" value="P:carboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00713">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="42665" checksum="88A1DEDAA18AB1EB" modified="2008-04-29" version="1">MGNRAKSLMGNIGLQVIIAMIIGGLVGLYMGESAAIFGPLGDLFINLIKMLVIPLVAVSIIAGAASLGNSPSAGKIGMGTFGFFIATSAIAVTLALVMGSIFKPGSGVDFSNHGDSFTQVTAEQGALPGAMDTIIGMIPTNVFESLTSGNILQILVFCIFLGIALTKVKGDGAEPIVKALNAIVEAFVWMINKVMLIAPIGVFGLMAHSVGTFGFQALEVVINLFVVFVASILIYAFIFFPLVVKFLSDVPVLKFISAMKKPQAMAMSTASSMATLPITMDTCEKELNVSKATSAFVLPLGATINMTGNAIYYGLVAMFFAQMFQVDLTMTAYAAIIFTSTLGAIGQAGVPGPSFLVVAVLLAAGIPIDGLPLLFALDRVFDMIRTSVNITGDAVCAVVMDKFNPEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHI8</accession>
    <name>B1KHI8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2596</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325213.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2596"/>
    <dbReference type="EnsemblBacteria" id="ACA86873">
        <property type="protein sequence ID" value="ACA86873"/>
        <property type="gene ID" value="Swoo_2596"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2596"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_27_6"/>
    <dbReference type="OMA" id="HPHFEFK"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031930">
        <property type="entry name" value="HK_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038428">
        <property type="entry name" value="HK_sensor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16750">
        <property type="entry name" value="HK_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="182"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="245"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="457" mass="51216" checksum="E10FC220A464FBC9" modified="2008-04-29" version="1" precursor="true">MLLPISGLFSHLQFKLFSYFAISLLAILLIATAIESLVLNKLLTLPSTTQEQLTELASEAKVFIRNSDIEGLTQWEKQQVFTLFILNNDLQALTKREMHPHFVFKLKYLKQLKQPMGDRVQKPLIAVPLGKHLINNKRQELTLVVQLNAALHPAQQLSSSLWVIRTLVGFAVLVMFSSILSKYLITPLTHLQAGTQALASGDLNTRIAQHFSTKEPEFYKLATEFDHMAEQVQQSMLNQQRLLRDVSHELRTPLARQELALHLLSKQLNDSHLTLLHRLEHENAEMSALINTMLNFSRLNNAYIDLNIQAVPINEIRSRSLNDIEFEAKAGQTIIWHSQPDTVTLITDVGLLTRAIDNVLRNALKYAGECCTIEVSYIKSPNGVVLTIMDDGPGIEHSELETVFNPFTRMDDARHSSQGGYGLGLAIVKQSMKLLGGEAVAENVDKGGLKISLHLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ7</accession>
    <name>B1KHJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2605</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325222.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2605"/>
    <dbReference type="EnsemblBacteria" id="ACA86882">
        <property type="protein sequence ID" value="ACA86882"/>
        <property type="gene ID" value="Swoo_2605"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2605"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_10_1_6"/>
    <dbReference type="OMA" id="KWEGILI"/>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0050">Antiport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="8">
        <location>
            <begin position="399"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="612"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="637" mass="69360" checksum="E0DC2E2B3E5F4B15" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS6</accession>
    <name>B1KHS6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4148</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326733.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4148"/>
    <dbReference type="EnsemblBacteria" id="ACA88404">
        <property type="protein sequence ID" value="ACA88404"/>
        <property type="gene ID" value="Swoo_4148"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4148"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_133_5_6"/>
    <dbReference type="OMA" id="GITRQYG"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033414">
        <property type="entry name" value="Sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17149">
        <property type="entry name" value="CHASE5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="299"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="546" mass="61535" checksum="B710D853CE31856E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV1</accession>
    <name>B1KHV1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4173</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.</text>
            <dbReference type="EC" id="3.5.1.28"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326758.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4173"/>
    <dbReference type="EnsemblBacteria" id="ACA88429">
        <property type="protein sequence ID" value="ACA88429"/>
        <property type="gene ID" value="Swoo_4173"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4173"/>
    <dbReference type="eggNOG" id="COG0860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014322_2_3_6"/>
    <dbReference type="OMA" id="KRYFAAN"/>
    <dbReference type="OrthoDB" id="1184688at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021731">
        <property type="entry name" value="AMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11741">
        <property type="entry name" value="AMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764503" description="N-acetylmuramoyl-L-alanine amidase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="393"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="439" mass="48206" checksum="4215221494F4EFF4" modified="2008-04-29" version="1" precursor="true">MIKIASFLQFFLLSVTLCSSFFVHSANKLDGVRIWAAPESTRVVFDLNKAPDFSYFTLTGPYRLVVDLKGTSTSVNLSKLANNSKLVKRVRISKPPSKGTLRLVIDLTKPVKSNLFSLPPTAPYGNRLVVDLDDSGSKKVVQTSQPKAKLRDVVVAIDAGHGGDDPGSIGPSGIYEKKVVLEIAKKVEAKINATPGMRAVMTRTGDYFVNLNKRSEIARTSKADLLVSIHADAFTSPQPRGASVWVLSMRRANSEIGRWLEHKEKHSELLGGAGEIIQNTDNEQYLAMTLLDMSMDRSMAISHNIADDVLSNLGRVTKLHKHKPESASFAVLKSPDIPSILVETGFISNHKEERLLSQREHQNNIAKAVHKGVLKYFEANPPVNSLMASKGSFKHNVRKGESLSVIAHKYQVSIASIKRANGLKSNTLRIGQKLVIPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI08</accession>
    <name>B1KI08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323832.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1193"/>
    <dbReference type="EnsemblBacteria" id="ACA85486">
        <property type="protein sequence ID" value="ACA85486"/>
        <property type="gene ID" value="Swoo_1193"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1193"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_7_6"/>
    <dbReference type="OMA" id="EHFITRY"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="157" mass="17781" checksum="025D96FAE63F80C8" modified="2008-04-29" version="1">MEKYEQLLISLRRVIRAIDIHSRQLNKQSGLTGPQLMVMQCIEQLEAPLAKEIAKEVALSPATVTTIIDRLESRELVIRTRSETDKRKVHLSLSETGKALLSHSPKPLQEHFITRYQNLEEWEQSQLLSSVERIAAMMDANELDAAPVLLVGQIQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI10</accession>
    <name>B1KI10_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transporter, BCCT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323834.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1195"/>
    <dbReference type="EnsemblBacteria" id="ACA85488">
        <property type="protein sequence ID" value="ACA85488"/>
        <property type="gene ID" value="Swoo_1195"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1195"/>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_679466_0_0_6"/>
    <dbReference type="OMA" id="MNDYHEF"/>
    <dbReference type="OrthoDB" id="988837at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="405" mass="45943" checksum="C48A0E6210369FE6" modified="2008-04-29" version="1" precursor="true">MTTWLTIGILFTFAAIAFVIYRWGNVECIGVTPVRTFTFIAILFTSGLDVGLIMFPLTEFAGYADLSASPEYGFTNPLAIEFGFWAFLIWAFYFLTCFYFCVIEPRVKFFEIPLIKFINNLVIIGTCAFTAYLLLTNLPWYLPEMGDGETIVSSFYLIVFVIIAAAVYSSTSIRYVRILSLASTWLFMALILIMWAGAFLSEGSGVGEFFTTFAMIGDYFGNIHHFVLPMNDYHEFYLFWWFAWSIMIGQFTSRFVGGLKTYQVLIAMMVFPSLPIAVWFTVLYYYSANEIATTGFYNLAMVVVGITFVVNSLDSLIRLYTDNLNLTVERFGKTKYILGNIALMSGLTLLFKLDFLQIQWVGALAIGLILACFGYILATKYKKVAAIERSPKENKIDFSKIELAN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI68</accession>
    <name>RS16_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsP</name>
        <name type="ordered locus">Swoo_1254</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323892.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI68"/>
    <dbReference type="SMR" id="B1KI68"/>
    <dbReference type="STRING" id="392500.Swoo_1254"/>
    <dbReference type="EnsemblBacteria" id="ACA85546">
        <property type="protein sequence ID" value="ACA85546"/>
        <property type="gene ID" value="Swoo_1254"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1254"/>
    <dbReference type="eggNOG" id="COG0228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100590_5_1_6"/>
    <dbReference type="OMA" id="GFYNPIA"/>
    <dbReference type="OrthoDB" id="1937072at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_S16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000196473" description="30S ribosomal protein S16">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <sequence length="83" mass="9343" checksum="BA9F44DBDE6CA979" modified="2008-04-29" version="1">MVTIRLARGGAKKRPFYNIVVADSRNARDGRFIERVGFFNPMARGQEETLRLDLDRVEHWVTNGAGTSERVAKLIKDARKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIF8</accession>
    <name>B1KIF8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tol-Pal system protein TolR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tolR</name>
        <name evidence="7" type="ordered locus">Swoo_2733</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2733"/>
    <dbReference type="EnsemblBacteria" id="ACA87009">
        <property type="protein sequence ID" value="ACA87009"/>
        <property type="gene ID" value="Swoo_2733"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2733"/>
    <dbReference type="eggNOG" id="COG0848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085305_1_3_6"/>
    <dbReference type="OMA" id="MMTHGVK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02203">
        <property type="entry name" value="TolR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014168">
        <property type="entry name" value="Tol-Pal_TolR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02801">
        <property type="entry name" value="tolR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="15723" checksum="78FED5858D000D43" modified="2008-04-29" version="1">MMQQGYQRKRRRPVAEINVVPYIDVMLVLLIIFMVTAPIVTQGVKVDLPQASSEALAADSKPPVVASIDADGDYFLDVGSSSSRETLDLEEIAIRVGAIVQLEPERPVVVKADRSIAYEKVIQLMVTLQGAGVPSVGLMTDSPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIN9</accession>
    <name>B1KIN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aminotransferase class V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4279</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326862.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4279"/>
    <dbReference type="EnsemblBacteria" id="ACA88535">
        <property type="protein sequence ID" value="ACA88535"/>
        <property type="gene ID" value="Swoo_4279"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4279"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_1_6"/>
    <dbReference type="OMA" id="PSYYMWR"/>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="91"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="462" mass="51919" checksum="04A48AA199AC663E" modified="2008-04-29" version="1" precursor="true">MNNDNKDVASGLNRRSFLKTSTGLVLAGAGTMMFPSVAAAKADELGPTQFRGHNSDHKLWKKVRKEFVLNKRTTYMNVGTSGSMPKSILKSYAKTNEMISANPWQSNIPTIELARQVAPGFGADEHELVLSRNTTDGMNSIINGLQFEEGDVVLTTHHEHPGATIPLKHVSERYNVEVVEVEIPVYTGENQVSEDDFVNAFADAVAEYGSRVRLIVFSHVTYTTGTSLPAKRICKEVAIPNRIPTLIDGAHTPGMLNLNFHDIDCDFYSGAGHKWQCGPGATGILYIRDNAQRLAEFWNDRPTPLWCINSSSSSTAIQARFQSIGQDNYPAKQALADACAMWEEIGRDVIEERVLDLSELCKQELFDTFPYANFYAPNIRELSSGLTTFNPFYDQHDGELLTQFRDRLHEEYGYIVRTTSFYNKKDDMQKIQTIRISTHLFHDEDDVIGLVKAMKRLYRNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ0</accession>
    <name>B1KIQ0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferritin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326873.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4291"/>
    <dbReference type="EnsemblBacteria" id="ACA88546">
        <property type="protein sequence ID" value="ACA88546"/>
        <property type="gene ID" value="Swoo_4291"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4291"/>
    <dbReference type="eggNOG" id="COG1633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_820880_0_0_6"/>
    <dbReference type="OMA" id="DLELWTI"/>
    <dbReference type="OrthoDB" id="935353at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026820">
        <property type="entry name" value="VioB/RebD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12902">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="36520" checksum="B21637322C1EB5A4" modified="2008-04-29" version="1">MKQEHLDWATAHFNTHLQGAVDLELWTIPYYMSAMYSIKDRSSDAYQLIRTVINQEMLHLQSAANIANAYGLSPKITPPTYEKNKIPHLNMSFNPSSITEPYMNHSFDIGPLDVERVNGMCLVELPDYGVTDEELILETIIDQYSSIGAFYRALSFGAKALKSDIKGGVRQVDAFSAFYRNMPNMTITESGELGINQVDLLIELITDQGEGQCKDGIEVPVVFQNTADDIEPEIDHFEKFRQIKESGKLPETYSVKDPCDYTEEDKKLEQILIQQFGELTKLLQALFNGDNPQNFFPVMAGVGAAITNCWKHGVTPKYSKTNQL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIT5</accession>
    <name>SYI_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="1">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ileS</name>
        <name type="ordered locus">Swoo_1291</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323929.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIT5"/>
    <dbReference type="SMR" id="B1KIT5"/>
    <dbReference type="STRING" id="392500.Swoo_1291"/>
    <dbReference type="PRIDE" id="B1KIT5"/>
    <dbReference type="EnsemblBacteria" id="ACA85583">
        <property type="protein sequence ID" value="ACA85583"/>
        <property type="gene ID" value="Swoo_1291"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1291"/>
    <dbReference type="eggNOG" id="COG0060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_7_0_6"/>
    <dbReference type="OMA" id="HLGTAWN"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02002">
        <property type="entry name" value="Ile_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023585">
        <property type="entry name" value="Ile-tRNA-ligase_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000189196" description="Isoleucine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="605"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="564"/>
        </location>
        <ligand>
            <name>L-isoleucyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:178002"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="608"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="903"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="906"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="923"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="926"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02002"/>
        </source>
    </evidence>
    <sequence length="940" mass="105573" checksum="9D57D8E96617ACED" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ61</accession>
    <name>B1KJ61_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2OG-Fe(II) oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2806</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325417.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2806"/>
    <dbReference type="EnsemblBacteria" id="ACA87081">
        <property type="protein sequence ID" value="ACA87081"/>
        <property type="gene ID" value="Swoo_2806"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2806"/>
    <dbReference type="eggNOG" id="COG3751">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079367_1_0_6"/>
    <dbReference type="OMA" id="GETEFFY"/>
    <dbReference type="OrthoDB" id="1139586at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PTHR10869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P4Hc" evidence="4">
        <location>
            <begin position="2"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="26170" checksum="D71230D1C1F2EED6" modified="2008-04-29" version="1">MDFIEVYPNAIPEDLCDRLIETFEKHQGVVDGRTGNGVDLTKKVSRDLTLDSFEDLFPLRNELLSYTLKHSTSYFNKYAMALMGAVSVQVADEKGQGVTLVPDNYQTLGEPRAEALVKYLYRSGTINVQKYPKSLGGYPHWHSEQFPQAGHNEALHRVVLYMFYLNDVEEGGETEFFYQERKLKPKKGTMVIAPAGFTHSHRGNMPISGDKYIATSWVMFNRAEQLYQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ90</accession>
    <name>B1KJ90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325446.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2835"/>
    <dbReference type="EnsemblBacteria" id="ACA87110">
        <property type="protein sequence ID" value="ACA87110"/>
        <property type="gene ID" value="Swoo_2835"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2835"/>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027866_1_0_6"/>
    <dbReference type="OMA" id="NQGYQYT"/>
    <dbReference type="OrthoDB" id="301791at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="18"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="156"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="220"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="615" mass="68612" checksum="4936FEA5CCD864FB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA2</accession>
    <name>B1KJA2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4321</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326900.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4321"/>
    <dbReference type="EnsemblBacteria" id="ACA88574">
        <property type="protein sequence ID" value="ACA88574"/>
        <property type="gene ID" value="Swoo_4321"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4321"/>
    <dbReference type="eggNOG" id="COG5549">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008630_0_0_6"/>
    <dbReference type="OMA" id="VIQWVHR"/>
    <dbReference type="OrthoDB" id="126943at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd04276">
        <property type="entry name" value="ZnMc_MMP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033413">
        <property type="entry name" value="DUF5117"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032534">
        <property type="entry name" value="EcxA_zinc-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034032">
        <property type="entry name" value="Zn_MMP-like_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16313">
        <property type="entry name" value="DUF4953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17148">
        <property type="entry name" value="DUF5117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764561" evidence="1">
        <location>
            <begin position="23"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5117" evidence="3">
        <location>
            <begin position="83"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4953" evidence="2">
        <location>
            <begin position="401"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="801" mass="88375" checksum="DD9D6DEFCAF59918" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL5</accession>
    <name>B1KJL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1396</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324034.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1396"/>
    <dbReference type="EnsemblBacteria" id="ACA85688">
        <property type="protein sequence ID" value="ACA85688"/>
        <property type="gene ID" value="Swoo_1396"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1396"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_1_0_6"/>
    <dbReference type="OMA" id="NPKAWIM"/>
    <dbReference type="OrthoDB" id="1945085at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22723" checksum="DBCC2C357A20C00A" modified="2008-04-29" version="1">MEYLIAVMLFAISSSVTPGPNNILVMTSGVNFGIKKSLPLLSGICVGFTVMLLLVGFGFAQLFELFPQLHFIIRCIGTLYLLYLAWLIAKSAGVMDTNTTNSQPKPLSFMKGALFQWVNAKAWVVSTGAIAAFTTLESNFYSQNLTIALTFLLVSFPCVGIWLLFGSMLKKLLKSEQNMRWFNYSMSGLLVLSVVPVINEIIIQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ4</accession>
    <name>B1KJQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324073.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1435"/>
    <dbReference type="EnsemblBacteria" id="ACA85727">
        <property type="protein sequence ID" value="ACA85727"/>
        <property type="gene ID" value="Swoo_1435"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1435"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_2_6"/>
    <dbReference type="OMA" id="SIIVNMD"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="339" mass="37786" checksum="D1DAE332B8E1D522" modified="2008-04-29" version="1">MNKKRVMTLADIALLANVSKSTASRALRNNPLINKNTRELVQEIALKHNFKVNATASNLRTQKTNTIAVVVMFDQKSGQAISDPFLMEILGTIADELTHFGYDMLLTTTKTATHDWYSYYYESKRADGLIIIGQGEHDQRIEALISTDLPFIVWGTEIHEKNYTTVGSDNRKGGYLAVSHLIEQGCQRIAFLGDINHTEVEQRWLGYQDAVAEAGLVVEDKLQIKTDFTSVDGYQSLRDHCLNDDVPIDGVFAVSDAIALGATKYLFEQNITIPKQVAVIGFDDISMSEYCSPSLSTIRQNTAAGGRLLVKLMLDKLNHLPVDSQLLNVEMIQRQSSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJX1</accession>
    <name>B1KJX1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Formate acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.54</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pyruvate formate-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_2883</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + formate = CoA + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:11844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Fermentation; pyruvate fermentation; formate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.54" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325494.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2883"/>
    <dbReference type="EnsemblBacteria" id="ACA87158">
        <property type="protein sequence ID" value="ACA87158"/>
        <property type="gene ID" value="Swoo_2883"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2883"/>
    <dbReference type="eggNOG" id="COG1882">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023898_0_0_6"/>
    <dbReference type="OMA" id="NEGHEGG"/>
    <dbReference type="OrthoDB" id="116406at2"/>
    <dbReference type="UniPathway" id="UPA00920">
        <property type="reaction ID" value="UER00891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01678">
        <property type="entry name" value="PFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005949">
        <property type="entry name" value="Form_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01255">
        <property type="entry name" value="pyr_form_ly_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="5 7 8" id="KW-0556">Organic radical</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="10">
        <location>
            <begin position="6"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="9">
        <location>
            <begin position="632"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="7">
        <location>
            <position position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="760" mass="84598" checksum="F281F09B0666CB6B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK10</accession>
    <name>B1KK10_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2924</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325533.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2924"/>
    <dbReference type="EnsemblBacteria" id="ACA87197">
        <property type="protein sequence ID" value="ACA87197"/>
        <property type="gene ID" value="Swoo_2924"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2924"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="ARMRYTW"/>
    <dbReference type="OrthoDB" id="76759at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767413" evidence="5">
        <location>
            <begin position="25"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="56"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="401"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="875" mass="98937" checksum="19F1B5AF8FC9F228" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK13</accession>
    <name>B1KK13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325536.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2927"/>
    <dbReference type="EnsemblBacteria" id="ACA87200">
        <property type="protein sequence ID" value="ACA87200"/>
        <property type="gene ID" value="Swoo_2927"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2927"/>
    <dbReference type="eggNOG" id="COG0708">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027539_0_3_6"/>
    <dbReference type="OMA" id="WWSYRGR"/>
    <dbReference type="OrthoDB" id="1893707at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09086">
        <property type="entry name" value="ExoIII-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="30743" checksum="08562A11EE83F030" modified="2008-04-29" version="1">MKIVSFNINGIRARLHQLQALIDSHQPDIIGLQETKAHDDVFPVADVEAMGYKVHYHGGKAHYGVAMLSKLEPVKVQKGFPTDGEDAQRRMIMGTFTQENGRPLTVLNGYFPQGENISHETKYPAKRQFYKDLMIYLNEHHSADEDIAVIGDINISPIDLDIGIGEPNAKRWLKTGKCSFQPEEREWLKTLMDWGLLDTFRELHPERVDRYSWFDYRSKGFDDNRGLRIDVVLATKSLADRLVESDVDYDLRGIEKPSDHAPIWSSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK98</accession>
    <name>B1KK98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome c-type biogenesis protein CcmF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4478</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327055.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4478"/>
    <dbReference type="EnsemblBacteria" id="ACA88729">
        <property type="protein sequence ID" value="ACA88729"/>
        <property type="gene ID" value="Swoo_4478"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4478"/>
    <dbReference type="eggNOG" id="COG1138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015041_3_0_6"/>
    <dbReference type="OMA" id="PLACWIW"/>
    <dbReference type="OrthoDB" id="213184at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032523">
        <property type="entry name" value="CcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003567">
        <property type="entry name" value="Cyt_c_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003568">
        <property type="entry name" value="Cyt_c_biogenesis_CcmF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43653">
        <property type="entry name" value="PTHR43653"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16327">
        <property type="entry name" value="CcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01410">
        <property type="entry name" value="CCBIOGENESIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01411">
        <property type="entry name" value="CCMFBIOGNSIS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00353">
        <property type="entry name" value="nrfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="612"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="8">
        <location>
            <begin position="89"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="CcmF_C" evidence="9">
        <location>
            <begin position="316"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="658" mass="72140" checksum="C75143435EDB13FA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKB7</accession>
    <name>B1KKB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Triosephosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324103.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1469"/>
    <dbReference type="EnsemblBacteria" id="ACA85757">
        <property type="protein sequence ID" value="ACA85757"/>
        <property type="gene ID" value="Swoo_1469"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1469"/>
    <dbReference type="eggNOG" id="ENOG502ZM4B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1967911_0_0_6"/>
    <dbReference type="OMA" id="MPSEELC"/>
    <dbReference type="OrthoDB" id="2075090at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766756" evidence="1">
        <location>
            <begin position="35"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="14389" checksum="8C6C2D82F881A618" modified="2008-04-29" version="1" precursor="true">MVQCLSRFRTHIAVRLKLISLMLFSVTIAFSGKAATYTEPQVLTQMTIGDSFSRVKQVNMPSEELCGRNDWYILDIQLDKNKAMFSALLAAKASGQKVHFQLTGCWQNYPKITHVYNCKNQYCTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKJ4</accession>
    <name>B1KKJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325547.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2938"/>
    <dbReference type="EnsemblBacteria" id="ACA87211">
        <property type="protein sequence ID" value="ACA87211"/>
        <property type="gene ID" value="Swoo_2938"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2938"/>
    <dbReference type="eggNOG" id="COG2370">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_675624_0_0_6"/>
    <dbReference type="OMA" id="YMATINL"/>
    <dbReference type="OrthoDB" id="760572at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032809">
        <property type="entry name" value="Put_HupE_UreJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13795">
        <property type="entry name" value="HupE_UreJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767158" evidence="2">
        <location>
            <begin position="23"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="414" mass="46988" checksum="07B1A61FE18F92A3" modified="2008-04-29" version="1" precursor="true">MLSVKKTMLLISLFIMPLSAFAHFGEAITRNIIVEPINNNDLIIIHIRTPAPLILLPSNWAGIDKQQPIPFTKIEKNGTKALYYLYEVDIREQLPQFKKIIMKEFYLKTAEGRRLEYKVGKIKIHNFHDRPVFNNLDNAYLAMSGEMFPHNPLELFDAVIDFSVTFSGADFSEDIFLVSTAGEKFKATDWLVNVITYPKSVNIGVKTIPGTLSEGVLLNHSSSSFIDFFTMGIEHIFTGLDHMLFIVLMTLSCSTMMLFFKNVTGFTLGHMITLTLGATISTLEGTWFIPMIELAIAMTILYMATINLVKRSDVGHWFVSFFIGLIHGFGFSFLMNKVFVQNQGFDLHSLLGFNLGIEAGQVLLYGGLILIFALIEWLEFRWLKQWRKGVAVISIMISLVWIYQRAMVLIPTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR4</accession>
    <name>B1KKR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase A domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325617.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3010"/>
    <dbReference type="EnsemblBacteria" id="ACA87281">
        <property type="protein sequence ID" value="ACA87281"/>
        <property type="gene ID" value="Swoo_3010"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3010"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_37_6"/>
    <dbReference type="OMA" id="NETYNAG"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA" evidence="2">
        <location>
            <begin position="220"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="420" mass="48579" checksum="A6A196A680FC52A4" modified="2008-04-29" version="1">MDKITVADHSHYPSFYWKIRWSFGLMTLLIFSLFWSLIYFAEDRLEVLSLHHWLDTEASQYTRDFDRLGFATPLPNPSEFSTYWSEEELPVWLTQYTQLGFFEHLIGTEDKHFIVSKHPSGRGLMYIVFQDDADDYLDNYEADLHFLTLFLGGFLTLAMLLYGLYFVRTLSKPLAKIQEKVSQMPPGNALFSVETKFRETREIESTLLESKINISNFFKREKEFSRFASHELRTPIMVIKGSTELLQKVPELPHVATKAIARLERASDEMELLTETFLLLGRAAIEPRYMATHSLELILTKQIDELALLFAKNDAGYKLRVSEPSKAHAPESFIAVIINNLIKNAFSYSVGDIDIELTGTELRICNRHDGHDLYNEGYGCGLVIVERICERMVWQFEHENTPEKYIAVVNFSSTENVNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ5</accession>
    <name>B1KKZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327127.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4551"/>
    <dbReference type="EnsemblBacteria" id="ACA88801">
        <property type="protein sequence ID" value="ACA88801"/>
        <property type="gene ID" value="Swoo_4551"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4551"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_468416_0_0_6"/>
    <dbReference type="OMA" id="ARPYFLN"/>
    <dbReference type="OrthoDB" id="1013118at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="473"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="583" mass="66589" checksum="4B9102FD702729C3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL17</accession>
    <name>B1KL17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4573</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327148.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4573"/>
    <dbReference type="EnsemblBacteria" id="ACA88823">
        <property type="protein sequence ID" value="ACA88823"/>
        <property type="gene ID" value="Swoo_4573"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4573"/>
    <dbReference type="eggNOG" id="COG3550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030167_3_0_6"/>
    <dbReference type="OMA" id="QMKLSVM"/>
    <dbReference type="OrthoDB" id="1293681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="11"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="149"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="418" mass="48038" checksum="305311F21C01B4CD" modified="2008-04-29" version="1">MSKQIEQVEGLNIQLHGIDIGVVAHYAGGKNILSFNPVYIAMCQHERPVLTLRQLQDPNYFNKPQIRSEKIPPVLSNLLPEGILREIVAKALQCHVNNEFSILAYLGTNLPGALVALPIKAGDMPSWALEQRLVTEPQQINVKHADTKFSLAGVQMKFSSSHVDGHYHIDQEISEDMWIIKTPSTVHKGVSVNEYTCMRLAEAAGANIPEIRLIKLDELEGLPNIRLPDETYAYGIKRFDRTHEGRVHTEDFAQIFGLYPSDKYQKVNYEQLGQVLFRTSNDRLDDVQQMARRLLINILLGNGDAHLKNWTIIYQDQRSPRLSPLYDVVFTAPYIEHDNLALNMTKSKQWYEMTMEHFENWSNSVGVPWVAIKPHLLDTMEKARSMWPEMLEELPMLNEHKEALQNHWQRLSPDFRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL28</accession>
    <name>B1KL28_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">3-deoxy-D-manno-octulosonic acid kinase</fullName>
            <shortName evidence="7">Kdo kinase</shortName>
            <ecNumber evidence="5 7">2.7.1.166</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">kdkA</name>
        <name evidence="8" type="ordered locus">Swoo_0068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>alpha-Kdo-(2-&gt;6)-lipid IVA + ATP = 4-O-phospho-alpha-Kdo-(2-&gt;6)-lipid IVA + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:61589"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.166"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the protein kinase superfamily. KdkA/RfaP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.166" evidence="5 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322718.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0068"/>
    <dbReference type="EnsemblBacteria" id="ACA84369">
        <property type="protein sequence ID" value="ACA84369"/>
        <property type="gene ID" value="Swoo_0068"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0068"/>
    <dbReference type="eggNOG" id="COG0478">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094226_0_0_6"/>
    <dbReference type="OMA" id="YYRGGLW"/>
    <dbReference type="OrthoDB" id="1643499at2"/>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00521">
        <property type="entry name" value="KDO_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022826">
        <property type="entry name" value="KDO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="28595" checksum="BC8B31B8EA5D86EC" modified="2008-04-29" version="1">MPIASPVTTPTEMQIISSPQGAIAVCHPTPDTISSNWFTMEYWQQKSAITGSSKGRYTTWFVKPDLSEGDDSQWVLRHYYRGGLMEKLSKDSYLYTGLHKTRAVAELALLVQLYNEGFPVPKPVAANVERHGLHYRADIIIERVEGAQDLVAKLSKSPMSDSQWQQLGSGIAQFHQRGVYHADLNAKNILITDDKFYLIDFDRGEIRQPSTKWQTANLERLQRSFNKEKGILSSLHFTQENWQALMVGYSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL56</accession>
    <name>B1KL56_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cobalt transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0096</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CbiQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322746.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0096"/>
    <dbReference type="EnsemblBacteria" id="ACA84397">
        <property type="protein sequence ID" value="ACA84397"/>
        <property type="gene ID" value="Swoo_0096"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0096"/>
    <dbReference type="eggNOG" id="COG0619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099017_0_0_6"/>
    <dbReference type="OMA" id="PGWWLCI"/>
    <dbReference type="OrthoDB" id="1891252at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="221" mass="25016" checksum="5DF038DAD0450269" modified="2008-04-29" version="1" precursor="true">MKTRRGVRHSTLERNADRGSKSIGWTAGALSLALILSSSAFFIPQDYLLALIVCDIVLVIHGVFRRGDFWVLGRVFLVQLAITLTLYYLIHGQEQLVQGALAVVRVLLAFIPGWWLSVSCKPEQIGEVLAWILPVKWAFVIAASLSLLPTMTTEIREIYQTQCLRGAKISPKALRDPRNWAELIHCVVFPLLIQLLKLSKQTAMAAQLRYFGKHKRTTHWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL68</accession>
    <name>B1KL68_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322758.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0108"/>
    <dbReference type="EnsemblBacteria" id="ACA84409">
        <property type="protein sequence ID" value="ACA84409"/>
        <property type="gene ID" value="Swoo_0108"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0108"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_4_1_6"/>
    <dbReference type="OMA" id="DIYNAMW"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="3">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="2">
        <location>
            <begin position="168"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="42679" checksum="E43C658A1D95AB3F" modified="2008-04-29" version="1">MKSILQRGFTTAEFEMRATKAQQKMRELEVDAILLTTEPNVRYFSGFHTQFWHSPTRPWFLILPAEGKPIAVIPEIGASGMAGTWVEDIHTWASPRPDDDGISIVASVLNSLPARFGRVGATLGIESHLRMPVANYLQLTTLVSKEFVDVSLAIHELRQVKSVAEIDKVREICRITNVGFDKIPGYAKAGMTEREICKQFGIDMLMEGADECPYIIAGSGQDGYDSIIMGPTDRVIEDGDVLIIDTGAVRDGYFSDFDRNWAFGHASEQTKAAYRATYEATTMGFEAARPGNTTSDIYNAMWKVLEANGALGNDVGRLGHGLGIELTERPSNTATDNTVLVPGMVMTLEPGMVYAPGKSMVHEENIVITETGAEWLSKRAEPELLIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB6</accession>
    <name>B1KLB6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324187.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1555"/>
    <dbReference type="ESTHER" id="shewm-b1klb6">
        <property type="family name" value="PolyAspartate-hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85841">
        <property type="protein sequence ID" value="ACA85841"/>
        <property type="gene ID" value="Swoo_1555"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1555"/>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060915_0_0_6"/>
    <dbReference type="OMA" id="GNSAGCQ"/>
    <dbReference type="OrthoDB" id="1195966at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764632" evidence="1">
        <location>
            <begin position="19"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="34593" checksum="8ED27F09C9447EE1" modified="2008-04-29" version="1" precursor="true">MKFFISIIIVLFSSCTFAANENINLGSGKFTIEGGKGHTEKKIDIYYHLPNSYDENTKVLIVIPGAGRNGWSYRDSWVEASEKHNVLILSPSYSEKLYPRFWNYNIARMLSDVKINKAKSAIESYTVVSDSNEWIFSDFDRVFDYSVSKLSLTAKKYDMFGHSAGGQILHRLALFDFKNKANRILASNSGWYTVPTFKENFPYGLNKGVSTREKISSAFKSKLTLFLGELDNEHETRGHLVRNPQLDIQGTYRLSRGKHFFKKSKELASNLNVKFNWNIHVVQGVGHDYKNMGKAAAIYLYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ9</accession>
    <name>B1KLQ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325692.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3085"/>
    <dbReference type="EnsemblBacteria" id="ACA87356">
        <property type="protein sequence ID" value="ACA87356"/>
        <property type="gene ID" value="Swoo_3085"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3085"/>
    <dbReference type="eggNOG" id="COG0417">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018487_0_0_6"/>
    <dbReference type="OMA" id="FVLTRHW"/>
    <dbReference type="OrthoDB" id="261704at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3 5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol_B_exo1" evidence="7">
        <location>
            <begin position="189"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol_B" evidence="6">
        <location>
            <begin position="404"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="807" mass="90618" checksum="D0B0C6BD08602612" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLT8</accession>
    <name>TIG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trigger factor</fullName>
            <shortName evidence="1">TF</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tig</name>
        <name type="ordered locus">Swoo_3114</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325721.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLT8"/>
    <dbReference type="SMR" id="B1KLT8"/>
    <dbReference type="STRING" id="392500.Swoo_3114"/>
    <dbReference type="EnsemblBacteria" id="ACA87385">
        <property type="protein sequence ID" value="ACA87385"/>
        <property type="gene ID" value="Swoo_3114"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3114"/>
    <dbReference type="eggNOG" id="COG0544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033058_2_0_6"/>
    <dbReference type="OMA" id="KGIKTQF"/>
    <dbReference type="OrthoDB" id="932993at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00303">
        <property type="entry name" value="Trigger_factor_Tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="PTHR30560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003095">
        <property type="entry name" value="Trigger_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="SSF102735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00115">
        <property type="entry name" value="tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0697">Rotamase</keyword>
    <feature type="chain" id="PRO_1000115581" description="Trigger factor">
        <location>
            <begin position="1"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="1">
        <location>
            <begin position="160"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00303"/>
        </source>
    </evidence>
    <sequence length="434" mass="47772" checksum="173334355E925F34" modified="2008-04-29" version="1">MQVSVETTQGLERRLTISVPAEQIEKAVNDSLKNEAKRARIPGFRPGKVPVSVINKRYGKAIRQDITGEVMQRNFVEAIIAEKLNPAGAPTFVPGESDAENFQFVATFEIYPEVELKGLEDIAVEQPTSDVTDADVDTMIETLRKQHATYEAVERAAADGDKAKINFVGSIDGEEFEGGKAEDFELQLGSGRMIPGFESGVEGHKAGEEFDIEVTFPEDYHAENLKGKVAKFAITLNEVQAANLPEVNDEFATLFGVAEGGLEALKAEISKNMGRELEQALKANVKEQVLNGLLEQNEIELPASLIAGEVEVLRKQAMQRFGDQAANMPELPADLFTEQAERRVKVGLLLGEVIKTNELKAEEERVQGLIASMASAYEDPSEVVEYYNGNQEMMQNMRNVALEEQAVEALLKTAKVTEKAVNFEEFMNKATQQG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLU0</accession>
    <name>SYC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="1">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysS</name>
        <name type="ordered locus">Swoo_3116</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325723.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLU0"/>
    <dbReference type="SMR" id="B1KLU0"/>
    <dbReference type="STRING" id="392500.Swoo_3116"/>
    <dbReference type="EnsemblBacteria" id="ACA87387">
        <property type="protein sequence ID" value="ACA87387"/>
        <property type="gene ID" value="Swoo_3116"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3116"/>
    <dbReference type="eggNOG" id="COG0215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013528_0_1_6"/>
    <dbReference type="OMA" id="AKYWMHN"/>
    <dbReference type="OrthoDB" id="952207at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000090873" description="Cysteine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="266"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <sequence length="459" mass="52109" checksum="034C76048EB589D2" modified="2008-04-29" version="1">MLKLYNSLTRQKEEFKPLQPGKVGMYVCGITIYDLCHIGHGRTFVAFDMIVRYLRYSGYDVNFLRNITDVDDKIIKRAAENKESCDSLTERLIGEMHKDFDSLNMKRPDFEPRATLHMAEIIEMVEKLIEKEHAYVSSNGDVLFSVSSFPEYGRLSGQNLEQLQAGARVEVEDSKRDPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGQHFDIHGGGSDLQFPHHENEIAQSCCAHNTPYVNYWMHTGMVMVDKEKMSKSLNNFFTIRDVLAHYDAATIRYFLLSGHYRSQLNYSEDNLKQAKSALARLYTALKDLDLTVEPAAAENFVSKFKQAMDDDFNTPEAYSVLFDMVREVNRLKVTDLAQASALAVRLKELAGVLGILEQDVDSFFKGESNDAEVAEVEALIAERNRARAEKDWPAADIARDGLNALGVILEDGPEGTTWRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW7</accession>
    <name>B1KLW7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acyl carrier protein</fullName>
            <shortName evidence="1">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">acpP</name>
        <name evidence="4" type="ordered locus">Swoo_4597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327172.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4597"/>
    <dbReference type="EnsemblBacteria" id="ACA88847">
        <property type="protein sequence ID" value="ACA88847"/>
        <property type="gene ID" value="Swoo_4597"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4597"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_5_4_6"/>
    <dbReference type="OMA" id="QTREDIF"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1 2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="80" mass="9005" checksum="D9B2E1F9686E491C" modified="2008-04-29" version="1">MQSREQILEALTQILVDEFEIDAEDITPEASLYQELDLDSIDAVDLVIKLQQMTGKKIKPEEFKAVRTVDDVVTAIEGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLX0</accession>
    <name>B1KLX0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabA/FabZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327175.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4600"/>
    <dbReference type="EnsemblBacteria" id="ACA88850">
        <property type="protein sequence ID" value="ACA88850"/>
        <property type="gene ID" value="Swoo_4600"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4600"/>
    <dbReference type="eggNOG" id="COG0764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078912_5_1_6"/>
    <dbReference type="OMA" id="VTQIDWA"/>
    <dbReference type="OrthoDB" id="1763197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016962">
        <property type="entry name" value="Dehydrase_ECs4332_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030962">
        <property type="entry name" value="Dehydrase_ECs4332_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="125" mass="14043" checksum="009ED14FD84E8F1C" modified="2008-04-29" version="1">MIKSSLPKILSSHTSDESIEWRLRIDADLPFFNGHFPEQAVLPGVTQLDWAIRMGCQHFGYPNDVATLEVLKFQQLMLPDSEVTLQISLNSAKTKLIFSYFDGDKRFGSGRIALSATSLAKVEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM10</accession>
    <name>B1KM10_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327214.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4640"/>
    <dbReference type="EnsemblBacteria" id="ACA88890">
        <property type="protein sequence ID" value="ACA88890"/>
        <property type="gene ID" value="Swoo_4640"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4640"/>
    <dbReference type="eggNOG" id="ENOG50343UK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141052_0_0_6"/>
    <dbReference type="OMA" id="YTIADEP"/>
    <dbReference type="OrthoDB" id="1854124at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="152" mass="17265" checksum="B7E6ED46DEC5666A" modified="2008-04-29" version="1">MASYQIIDEPRAGRLSNYTVNPMWPLLSAMLGGPVFSWLWYLFNSFALNGPNRLKEILTIFVAFAAFIGVYQFGASFWNSGYFVDANVRYFYLFGITVQFVFSYILLVLQSDSFELYEHFNGHVASPVIGFVLAFVIGKPLQLFLVNLVWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ1</accession>
    <name>B1KMJ1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Swoo_1704</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324335.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1704"/>
    <dbReference type="EnsemblBacteria" id="ACA85989">
        <property type="protein sequence ID" value="ACA85989"/>
        <property type="gene ID" value="Swoo_1704"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1704"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_2_6"/>
    <dbReference type="OMA" id="LYVNIYD"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="16">
        <location>
            <begin position="179"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="236"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="313"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="364"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="442"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="510"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="885"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="17">
        <location>
            <begin position="1072"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="934"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="9">
        <location>
            <position position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACA85989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1168" mass="130051" checksum="7A51AD86AFA6FD3E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ8</accession>
    <name>B1KMJ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324342.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1711"/>
    <dbReference type="EnsemblBacteria" id="ACA85996">
        <property type="protein sequence ID" value="ACA85996"/>
        <property type="gene ID" value="Swoo_1711"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1711"/>
    <dbReference type="eggNOG" id="COG1664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072799_5_0_6"/>
    <dbReference type="OMA" id="FIGMRVR"/>
    <dbReference type="OrthoDB" id="1968497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35024">
        <property type="entry name" value="PTHR35024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="14479" checksum="D831E44195C30918" modified="2008-04-29" version="1">MFTKKRSNTGLTFVAQGTKLSGESHFAGEALIGGEVYGKVSSSGKITIEVDGHIDGELSCNELKVSGSFKGKLKCDKLNITSTGTVEGEIACESMEIFEGGQFIGMRVREEVALLNTIEQQELLNSDVEGELQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN12</accession>
    <name>B1KN12_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4719</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327287.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4719"/>
    <dbReference type="EnsemblBacteria" id="ACA88969">
        <property type="protein sequence ID" value="ACA88969"/>
        <property type="gene ID" value="Swoo_4719"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4719"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106706_0_0_6"/>
    <dbReference type="OMA" id="HDYGFPK"/>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="221" mass="25513" checksum="B20254173D3543F1" modified="2008-04-29" version="1">MFPWNEIDTVLLDMDGTLLDLHFDNHFWLNLVPQELSRQRGIDTEEAIKLVEAAYEKVFGTLEWYCLDYWQNELQLDILNLHKTLVDRIQLRQDSMPFLKALGAENKSRILVTNAHPNSLALKLEHTDLALGLDQMLSSHETGYPKEHPYFWQHLFMQFSLDPSRCLFIDDSEVILQASRDAGVGHQLGITNPDSQKPHKVFSDFPAIGDYHLLLDDLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN14</accession>
    <name>B1KN14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4721</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327289.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4721"/>
    <dbReference type="EnsemblBacteria" id="ACA88971">
        <property type="protein sequence ID" value="ACA88971"/>
        <property type="gene ID" value="Swoo_4721"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4721"/>
    <dbReference type="eggNOG" id="COG1398">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027359_1_2_6"/>
    <dbReference type="OMA" id="DMRDWAQ"/>
    <dbReference type="OrthoDB" id="797871at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="321" mass="36664" checksum="75CABD3A17847F20" modified="2008-04-29" version="1">MLNTDRVYSNDKHSAFSGTVKWKPVKSIWFLTHLLATILIAPFVLSFSAFFVFLILTAITLCFGHSLGMHRLLIHRSYECPKWMEYLFVYLGVLVGMAGPIGMMIQHDLRDWAQRQTQCHDYLLHGSKILKDGWWQLNCDLVLNNPPEFNIEESVSLNKFYQFIEKTWMLQQLVLAIPLFLIGGIPWLVWGVSVRIVISVGGHWLIGYFAHNKGDKTWEVEGAAVQGHNIKVAGFLSMGEAWHNNHHAYPGSAMLGLYSDEPDPGWWVLNALHNLRIVKNIKLPKQLPARSELVKVSDNIDSRVERVPEDCEVAKFIRKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN17</accession>
    <name>B1KN17_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type II secretion system protein N</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">General secretion pathway protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4724</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP N family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327291.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4724"/>
    <dbReference type="EnsemblBacteria" id="ACA88974">
        <property type="protein sequence ID" value="ACA88974"/>
        <property type="gene ID" value="Swoo_4724"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4724"/>
    <dbReference type="eggNOG" id="ENOG5032RTB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092754_1_0_6"/>
    <dbReference type="OMA" id="NDIAFEG"/>
    <dbReference type="OrthoDB" id="1565792at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022792">
        <property type="entry name" value="T2SS_protein-GspN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01203">
        <property type="entry name" value="T2SSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="27240" checksum="699D0E18D12F3499" modified="2008-04-29" version="1" precursor="true">MNLTKKIILGVVIYLGFIIALFPASVAVKLAPLPNNISVSGVSGTIWSGKIETLSIQRRQLELVQWQLSPWGLFLGKANLDLVIGNRGTAVNGKGLVSLSGSGIDAEGLRFEAPSSFLLGNTRLPFRTEVSGDISLFVDTLQQGIPLCEQLNGKLFLNTVQVKNQFGNYPLGDIELGLSCEDGNVKVRSDEQMNQLGFDGTVLVKAEKMVQVSAKIKETASQPADLKKALAFLGKKDSQGYYPISYQGRLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN95</accession>
    <name>B1KN95_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Spondin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322941.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0291"/>
    <dbReference type="EnsemblBacteria" id="ACA84592">
        <property type="protein sequence ID" value="ACA84592"/>
        <property type="gene ID" value="Swoo_0291"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0291"/>
    <dbReference type="eggNOG" id="ENOG502ZFV4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097554_0_0_6"/>
    <dbReference type="OMA" id="SRVHRWL"/>
    <dbReference type="OrthoDB" id="1396644at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009465">
        <property type="entry name" value="Spondin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038678">
        <property type="entry name" value="Spondin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06468">
        <property type="entry name" value="Spond_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766885" description="Spondin domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin" evidence="2">
        <location>
            <begin position="37"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="234" mass="24189" checksum="68CD08F0D482E23A" modified="2008-04-29" version="1" precursor="true">MNLNKVSKILILNGLMLAAPSMAAELEISITNLTQGNHFTPILITAHDNTSHQFQAGEMASPALQKMAEGGDIADLMAAATGNNELTVGNPAEGLLAPGGKVNEIMLDTQSMTHLSIVAMVLPTNDAFIGLDAWEIPTTPGTYTINVNAYDAGTEANDEIVNGGGMPGAPGIPAAPGMDAGMNGTGVSDTSANDKVHIHAGVLGDMDEAGGISDLDSRIHRWLNPVARVVVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE1</accession>
    <name>B1KNE1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324364.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1733"/>
    <dbReference type="EnsemblBacteria" id="ACA86018">
        <property type="protein sequence ID" value="ACA86018"/>
        <property type="gene ID" value="Swoo_1733"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1733"/>
    <dbReference type="HOGENOM" id="CLU_2939270_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="60" mass="6872" checksum="395D599533165A26" modified="2008-04-29" version="1">MVNTQELNDCDYLLCFNDQRENLAKKIEKNGGDKLSVLKTNLSIVLVDDSETESYIRGYN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF6</accession>
    <name>SSTT_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine/threonine transporter SstT</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Na(+)/serine-threonine symporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sstT</name>
        <name type="ordered locus">Swoo_1748</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-serine(in) + Na(+)(in) = L-serine(out) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29575"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="1">
            <dbReference type="Rhea" id="RHEA:29577"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonine(in) + Na(+)(in) = L-threonine(out) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:69999"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="1">
            <dbReference type="Rhea" id="RHEA:70001"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324379.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNF6"/>
    <dbReference type="SMR" id="B1KNF6"/>
    <dbReference type="STRING" id="392500.Swoo_1748"/>
    <dbReference type="EnsemblBacteria" id="ACA86033">
        <property type="protein sequence ID" value="ACA86033"/>
        <property type="gene ID" value="Swoo_1748"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1748"/>
    <dbReference type="eggNOG" id="COG3633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044581_0_0_6"/>
    <dbReference type="OMA" id="PVNLQLC"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032329">
        <property type="term" value="P:serine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015826">
        <property type="term" value="P:threonine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01582">
        <property type="entry name" value="Ser_Thr_transp_SstT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023025">
        <property type="entry name" value="Ser_Thr_transp_SstT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0029">Amino-acid transport</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0769">Symport</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000197565" description="Serine/threonine transporter SstT">
        <location>
            <begin position="1"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01582"/>
        </source>
    </evidence>
    <sequence length="409" mass="42313" checksum="0BA307DD93E641BD" modified="2008-04-29" version="1">MNQNQSFLAKMANGSLVLQILVGIIAGIIVATLSESAAQSVAFLGQLFVGALKAIAPILVFILVAASIANQKKNAKTNMRPIVILYLFGTFAAAVTAVLMSFAFPTTLALTLDAAQASPPEGIGEVIHTLLFKLVDNPVNALMTGNYIGILAWGVGLGLALHHATDSTKQVFADVSHGVSQMVRFIIRLAPIGIFGLVSSTFASTGFSAIAGYMHLLLVLLGAMAIMALIINPAIVYFKIRRNPYPLVFTCIRESGVTAFFTRSSAANIPVNMALCEKLKLHEDTYSVSIPLGATINMGGAAITITILTLAAANTMGVQVDILTAILLSVVAGISACGASGVAGGSLLLIPLACSLFGISNDIAMQVVAVGFIIGVIQDSAETGLNSSTDVIFTAAACEAAERKENAGA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNK9</accession>
    <name>ASTB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-succinylarginine dihydrolase</fullName>
            <ecNumber evidence="1">3.5.3.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">astB</name>
        <name type="ordered locus">Swoo_1802</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19533"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58241"/>
            <dbReference type="ChEBI" id="CHEBI:58514"/>
            <dbReference type="EC" id="3.5.3.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the succinylarginine dihydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324432.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNK9"/>
    <dbReference type="SMR" id="B1KNK9"/>
    <dbReference type="STRING" id="392500.Swoo_1802"/>
    <dbReference type="EnsemblBacteria" id="ACA86086">
        <property type="protein sequence ID" value="ACA86086"/>
        <property type="gene ID" value="Swoo_1802"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1802"/>
    <dbReference type="eggNOG" id="COG3724">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053835_0_0_6"/>
    <dbReference type="OMA" id="IAPTNCQ"/>
    <dbReference type="OrthoDB" id="567590at2"/>
    <dbReference type="UniPathway" id="UPA00185">
        <property type="reaction ID" value="UER00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009015">
        <property type="term" value="F:N-succinylarginine dihydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:arginine catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019545">
        <property type="term" value="P:arginine catabolic process to succinate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01172">
        <property type="entry name" value="AstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037031">
        <property type="entry name" value="AstB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007079">
        <property type="entry name" value="SuccinylArg_d-Hdrlase_AstB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04996">
        <property type="entry name" value="AstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03241">
        <property type="entry name" value="arg_catab_astB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0056">Arginine metabolism</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000138030" description="N-succinylarginine dihydrolase">
        <location>
            <begin position="1"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01172"/>
        </source>
    </evidence>
    <sequence length="445" mass="48802" checksum="BA0089D020B1AF8C" modified="2008-04-29" version="1">MKHFEANFDGLVGPTHNYAGLSFGNVASFSNASAVSDPKSAAKQGLKKAKALADMGMVQGMLAPQERPDLHTLRRIGFSGTDAEILNKAAKEAPALLRACCSASSMWTANAATVSPSADTQDGKLHFTPANLVDKLHRSIEPVTTGNILAATFNNSRHFSHHQHLPEHSSFGDEGAANHTRLCENYGNAGVELFVYGQEATNPNAPKPQKYPARQTLEASQAIARLHGLSEENTVYLSQNPDVIDQGVFHNDVIAVGNQNVLFYHQQAFLDTQNKFDEIQQKFGDSKVHFIEVPTAKVSIEDAVKSYLFNTQIITLPSGEMAIIAPTNCQENPAVFAYLNELVTLGTPIKQVNYFDVKQSMQNGGGPACLRLRVAMNDMELAAVNQNTLMNDALFTRLNAWVDKHYRDRLSVDDLADPQLIIESRTALDELTQIMKLGSVYQFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNW2</accession>
    <name>B1KNW2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325906.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3301"/>
    <dbReference type="EnsemblBacteria" id="ACA87570">
        <property type="protein sequence ID" value="ACA87570"/>
        <property type="gene ID" value="Swoo_3301"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3301"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_0_6"/>
    <dbReference type="OMA" id="CIARIGH"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="302" mass="34217" checksum="0972EA796E3091CE" modified="2008-04-29" version="1">MSQEKPLDLNLLRVFSIVCKTASFSRAAEELNLTQSSVSNAIARLKLSIGEELFIRVGRGVKPTSVALNLYQQLEQPLLAIEQVVSGLHLFDPKQSKRSFYVYANETIIQLLQTRVDEYLCDSAIDIVFRETPIGEEQIQMDLQLEKVDLALDITQPHLASFASTKVMQDRLNCVVRKEHPRIQGSLSTEQYFAEKHIIHNMRRSNLSMADLMTKEVLPKREMYGEQSSLLNMLATAAKSNAIAVATQSYTDAYAELFGLQVLPLPFVTEPIDLYMVWCKKLQHNAANLWLRETLLLLIKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNW4</accession>
    <name>B1KNW4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alginate_exp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325908.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3303"/>
    <dbReference type="EnsemblBacteria" id="ACA87572">
        <property type="protein sequence ID" value="ACA87572"/>
        <property type="gene ID" value="Swoo_3303"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3303"/>
    <dbReference type="eggNOG" id="ENOG502Z7YP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045097_0_0_6"/>
    <dbReference type="OMA" id="HVGWRQD"/>
    <dbReference type="OrthoDB" id="200714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025388">
        <property type="entry name" value="Alginate_export_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13372">
        <property type="entry name" value="Alginate_exp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764702" description="Alginate_exp domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate_exp" evidence="2">
        <location>
            <begin position="39"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="396" mass="43978" checksum="0AB57CBFC203CA61" modified="2008-04-29" version="1" precursor="true">MKVRALTLAILTSLSASAIAADTVDPLKKAFIDDSEIKLQFRLRYEQADVDNVDDQNQTTLRTRLNYKTGDIYNFFALAEVDDVRSTDDEPLIADYEYTQINQAFIGYKAPADTLLKYGRQRILLDNQRFVGGVGFRQNEQTYDAFSIQNTAVKHLTAYYAYVNNVNRIFPEGSGKDEHKNETSLLNVNYKGLDFVKLSGYAYLIDNINVAKFSTDTYGIRAAGGIKLDKIKLNYEAEFAQQSEGGDNPTSYTANYYKLGAGVGFNGFGAKLGYEVLGSDDGKAGFVTPLATLHAFNGWTDKFLFGGAGNWENGIVDTHFILTAKVAGLKLLAKYHKFDSDFGDIDMGKEWGFAATYPFAKHYDVGVKYASFSGADAGYGFSNDTDKLWLTLQAKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ2</accession>
    <name>B1KNZ2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2063 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327340.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4774"/>
    <dbReference type="EnsemblBacteria" id="ACA89023">
        <property type="protein sequence ID" value="ACA89023"/>
        <property type="gene ID" value="Swoo_4774"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4774"/>
    <dbReference type="eggNOG" id="COG3219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086594_0_1_6"/>
    <dbReference type="OMA" id="MARFHIR"/>
    <dbReference type="OrthoDB" id="1675974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018640">
        <property type="entry name" value="DUF2063"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044922">
        <property type="entry name" value="DUF2063_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09836">
        <property type="entry name" value="DUF2063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2063" evidence="1">
        <location>
            <begin position="5"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="253" mass="28906" checksum="DDACBA469820862B" modified="2008-04-29" version="1">MRLAEWQEAFVCALSKSRADEALLSLVNSREAERLSVYRNNSKQALAAALGISFPICKQVLGEVCFEQLAQRYQVLQPLKLSNLNLYGEHFPELLTDTIARRLEFEGLEYLADLAKLEWLIQLSYYAADKLACQPLSDISSLTELQQASLIMLLRPDVHLLSSPFPLYEIWLKYQQEQDEIKIRSPQKHYFFAIYREPFKPKVQRISSELYRVLGDIQQSRTLGQINESGVDMSALNSGITQGWVCGFHLEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP11</accession>
    <name>B1KP11_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="9">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">moaA</name>
        <name evidence="11" type="ordered locus">Swoo_4793</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327359.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4793"/>
    <dbReference type="EnsemblBacteria" id="ACA89042">
        <property type="protein sequence ID" value="ACA89042"/>
        <property type="gene ID" value="Swoo_4793"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4793"/>
    <dbReference type="eggNOG" id="COG2896">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009273_0_1_6"/>
    <dbReference type="OMA" id="DGKFFTC"/>
    <dbReference type="OrthoDB" id="1199289at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="7"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="259"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA89042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="36858" checksum="89040758E1478292" modified="2008-04-29" version="1">MSQLQDNFGRRFHYLRMSVTDVCNFKCTYCLPDGYRPNGRSKFLALSEIENLVAAFAEVGTQKIRITGGEPTLRKDFTDIIRAVADNDKIKTIATTTNGYRLEKHAKEWYDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAALDAGFERVKINAVLLKGLNDKDLPRFLHWIKNTPIDLRFIELMETGLGRDYFQAHHLAGADIKSQLLADGWGLDQSAVDDGPAQNFSRDDHKGRIGLIMPYDKHFCASCNRLRVSANGKLHLCLFTENGVDLRDLLQDESHRPELIKRLHGQLAQKKETHFLHDGITGVTQHLASIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP47</accession>
    <name>B1KP47_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327395.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4829"/>
    <dbReference type="EnsemblBacteria" id="ACA89078">
        <property type="protein sequence ID" value="ACA89078"/>
        <property type="gene ID" value="Swoo_4829"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4829"/>
    <dbReference type="eggNOG" id="COG4531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_440605_0_0_6"/>
    <dbReference type="OMA" id="HRYSEVT"/>
    <dbReference type="OrthoDB" id="572496at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="515" mass="56150" checksum="FA60C3F1B0B8E292" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP66</accession>
    <name>B1KP66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly protein PilM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322985.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0335"/>
    <dbReference type="EnsemblBacteria" id="ACA84636">
        <property type="protein sequence ID" value="ACA84636"/>
        <property type="gene ID" value="Swoo_0335"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0335"/>
    <dbReference type="eggNOG" id="COG4972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050686_1_0_6"/>
    <dbReference type="OMA" id="EKVQDRQ"/>
    <dbReference type="OrthoDB" id="1750212at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005883">
        <property type="entry name" value="PilM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11104">
        <property type="entry name" value="PilM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019169">
        <property type="entry name" value="PilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01175">
        <property type="entry name" value="pilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="1">
        <location>
            <begin position="13"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="39355" checksum="780B7771A430DDA7" modified="2008-04-29" version="1">MLSNLWKRQAPQMVGIDVGSHEIKAILLSKTADGYKILSHAAVPLKKGAVNDHEIRDADAVVESLKQVKRILPKGAKLAAVAVSGSAVMTKVIYMDASLSEEEMEAQIEIEADNLIPYSLDEVSIDFETLNVNSTDPTKVDVLLSACRTENIDARVDSLDEVNIEVKVVDVEGYALGRSYEVVAAQLPEGTENKIVALVDIGANITTFAVVENGQTSFIREQAFGGEQFTQSILSFYGMSHEQAEKAKLEGDLPRNYMFEVLSPFQTQLLQQIKRTLQIYCTSSGKDKVDHIILCGGTSKLEGMANLLTNELGVHTIIADPFQGCLHADEDIKNSLKPDISKYMVACGLALRSYSQWRT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP71</accession>
    <name>AROK_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Shikimate kinase</fullName>
            <shortName evidence="1">SK</shortName>
            <ecNumber evidence="1">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroK</name>
        <name type="ordered locus">Swoo_0340</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the shikimate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322990.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP71"/>
    <dbReference type="SMR" id="B1KP71"/>
    <dbReference type="STRING" id="392500.Swoo_0340"/>
    <dbReference type="EnsemblBacteria" id="ACA84641">
        <property type="protein sequence ID" value="ACA84641"/>
        <property type="gene ID" value="Swoo_0340"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0340"/>
    <dbReference type="eggNOG" id="COG0703">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057607_2_2_6"/>
    <dbReference type="OMA" id="IGKHLFE"/>
    <dbReference type="OrthoDB" id="1392851at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000094413" description="Shikimate kinase">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <sequence length="171" mass="19098" checksum="9183169488E59906" modified="2008-04-29" version="1">MAEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIAWVFDVEGEEGFRIRETQVVADLTEKQGIVLATGGGSIQSKEIRNNLSARGIVVYLETTIDKQVARTQRDKRRPLLQVEDPREVLENLAATRNPLYEEIADVIVKTDEQSAKVVANQIIEQLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPI2</accession>
    <name>B1KPI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324481.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1851"/>
    <dbReference type="EnsemblBacteria" id="ACA86135">
        <property type="protein sequence ID" value="ACA86135"/>
        <property type="gene ID" value="Swoo_1851"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1851"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_19_8_6"/>
    <dbReference type="OMA" id="FGMGVKD"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="18193" checksum="49A3F3B9A0B0904B" modified="2008-04-29" version="1">MDVTIRHTEPSDFEGVQSLYTQPSCYSGTLQLPYPSLSNWQARLANMGKDHYNLVALIDNQIVGQIGMIIMDNPRRKHVANIGMSVSHQLQNQGIGTQLLEAILDLADNWLALKRIELEVYTDNPAAIALYKKAGFVIEGTAKAYAFRDGEYVDSHLMARLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPU4</accession>
    <name>B1KPU4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Auxin Efflux Carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3358</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the auxin efflux carrier (TC 2.A.69) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325962.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3358"/>
    <dbReference type="EnsemblBacteria" id="ACA87627">
        <property type="protein sequence ID" value="ACA87627"/>
        <property type="gene ID" value="Swoo_3358"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3358"/>
    <dbReference type="eggNOG" id="COG0679">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056175_2_1_6"/>
    <dbReference type="OMA" id="TTFFWTL"/>
    <dbReference type="OrthoDB" id="2033473at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="35442" checksum="907541EAFA2D57EA" modified="2008-04-29" version="1" precursor="true">MSPILTPLFAVLAMMLLGSLVQKLKILPIDTDLVLNQYVYYVAFPAIMLIALAETPIHEILQWGFIAGYSLAMLLTYLLVVLVSHITNKGRADLAALRALNTTFGNTAFIGIPLLSMLYPEQQSALTAAAIASLLSVIVFALVLVSIELYQEKGDNKRERKQSPLLIITLSLIQNPVVIGSAIGVFLSAIEFKLFEPLSIMLRDIGMTSSPCALFAIGMVLVKASGNHEISHQKPKWLDLIAELSWINLAKLFIQPALAYILLSAFGIEGDYFIMGVLLAALPTAASVYLLAERYQVKVMVSAQAIMLGTLLSIVTLPLIQSFLH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ38</accession>
    <name>ATPF_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-type ATPase subunit b</fullName>
            <shortName evidence="1">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpF</name>
        <name type="ordered locus">Swoo_4902</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase B chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327468.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ38"/>
    <dbReference type="SMR" id="B1KQ38"/>
    <dbReference type="STRING" id="392500.Swoo_4902"/>
    <dbReference type="EnsemblBacteria" id="ACA89151">
        <property type="protein sequence ID" value="ACA89151"/>
        <property type="gene ID" value="Swoo_4902"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4902"/>
    <dbReference type="eggNOG" id="COG0711">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079215_4_5_6"/>
    <dbReference type="OMA" id="FAWKPIL"/>
    <dbReference type="OrthoDB" id="1999641at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0138">CF(0)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000368769" description="ATP synthase subunit b">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <sequence length="156" mass="17279" checksum="AA27EEBDE7DCE0A1" modified="2008-04-29" version="1">MNINATLLGQTVAFIIFVWFCMKFVWPPLMNAIEERQKRIADGLADADRAVKDLELAQAKATDQLKDAKATANEIIEQANKRKAQIVDEAKAEADAERAKIIAQGQAEIEAERNRVKEDLRKQVATLAIAGAEKILERSIDEAAHSDIVNKLVAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQQ3</accession>
    <name>B1KQQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324638.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2008"/>
    <dbReference type="EnsemblBacteria" id="ACA86292">
        <property type="protein sequence ID" value="ACA86292"/>
        <property type="gene ID" value="Swoo_2008"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2008"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1015250_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="274" mass="30556" checksum="9C4232A50C278C52" modified="2008-04-29" version="1">MRIKVLQTQRKASIQEALKYIVKLVAQACQEPQDFIVLPEHALIQPECGLDEDTAIKIQETFSSLALKYNTYILTGSWLEVQGSHTVNITRLLDRKGHCLASVKHAFDMKENTEERYPVIETDMGKVGILLGSDFWNIESSRIQTLQGAELVLVSGSLTTKNLNSKQCSIWGIATLNCIAIAYASTGTSVDTKDESAGGSMIALPSNIQAKAEWNPEVIQAMWDDGLMSKTREADLTFKNTLWFGLWARRKELYAPLSMAEDLSHSSPTNVEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR7</accession>
    <name>B1KQR7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Na(+)-translocating NADH-quinone reductase subunit A</fullName>
            <shortName evidence="2">Na(+)-NQR subunit A</shortName>
            <shortName evidence="2">Na(+)-translocating NQR subunit A</shortName>
            <ecNumber evidence="2">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NQR complex subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NQR-1 subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nqrA</name>
        <name evidence="4" type="ordered locus">Swoo_3405</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NqrA family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3405"/>
    <dbReference type="EnsemblBacteria" id="ACA87673">
        <property type="protein sequence ID" value="ACA87673"/>
        <property type="gene ID" value="Swoo_3405"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3405"/>
    <dbReference type="eggNOG" id="COG1726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046656_0_0_6"/>
    <dbReference type="OMA" id="SHRAMMA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00425">
        <property type="entry name" value="NqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008703">
        <property type="entry name" value="NqrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022615">
        <property type="entry name" value="NqrA_C_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37839">
        <property type="entry name" value="PTHR37839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05896">
        <property type="entry name" value="NQRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11973">
        <property type="entry name" value="NQRA_SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01936">
        <property type="entry name" value="nqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0915">Sodium</keyword>
    <keyword evidence="2" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 2" id="KW-0813">Transport</keyword>
    <keyword evidence="2 4" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NQRA_SLBB" evidence="3">
        <location>
            <begin position="270"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="456" mass="49963" checksum="4ACC8119378AD3EB" modified="2008-04-29" version="1">MFVMAEFKDQIKTVTKGLDVPIAGEPKQLIEDRFTSSHVALLGEEYVGLKPTMMVEVGDTVKKGQPLFEDKKTPGVLFTAPASGEIIAINRGERRVLQSVVIRCQGDDALVFEASEDPSRLSREAVQANLVKSGLWTALRTRPFSRLPQLDTIPAAIFVTATDTNPLAPEPRIIIGEQSEAFATGMAVLTRLTQGKVYLCQDAGESLPGHDLAQVETKRFTGVHPAGLVGTHIHFTLPVSLERQVWHIGYQDVIAFGKLFQTGELYTDRVVSLAGPDVLNPRLVRTQLGAELSEIVKDQLKPGFSRVVSGSVLSGHTAAGVHDYLGRFHNQISALTEDSQHELLSWVRGGSEKFSITRAVTSRFKGAKKLFQMTTHTGGSARAMMAFGQLDRVMPLDILPTLLVRDLVVRDTDEAQELGALELDEEDLALCTFVCPGKYDFGKELRACLDIIEREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQX6</accession>
    <name>B1KQX6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isocitrate dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="2">1.1.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.41" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326067.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3466"/>
    <dbReference type="EnsemblBacteria" id="ACA87732">
        <property type="protein sequence ID" value="ACA87732"/>
        <property type="gene ID" value="Swoo_3466"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3466"/>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_6"/>
    <dbReference type="OMA" id="TCAHKAN"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="1">
        <location>
            <begin position="5"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="335" mass="35999" checksum="D2231373ED9B3403" modified="2008-04-29" version="1">MSKRTITVIPGDGIGPSIIDAALKILDKAGCDFEYEFADAGLAALEKQGELLPQRTLDMIEKNRITLKGPLTTPVGEGFTSINVSLRKQFSLYANVRPVLSFKGTQARYDKIDIITVRENTEGMYSGLGQTVSDDGATAEATSIITRQGAEQITTFAYELARKENRKKVTIVHKANIMKSTSGLFLKVAREVSLRYPDIITEEMIVDATCMKLVMNPENFDVMVTTNLFGDILSDLCAGLVGGLGMAPGANIGKDAAIFEAVHGSAPDIAGKNLANPTSVILASIQMLEYLGMADKAENIRSAVTAVISEGDRTTRDLGGTHGTTDFTQAVIDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR63</accession>
    <name>B1KR63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323228.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0584"/>
    <dbReference type="EnsemblBacteria" id="ACA84880">
        <property type="protein sequence ID" value="ACA84880"/>
        <property type="gene ID" value="Swoo_0584"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0584"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052955_0_0_6"/>
    <dbReference type="OMA" id="IATYWIS"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="2"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="403" mass="44176" checksum="CC9F2EA500A918E5" modified="2008-04-29" version="1" precursor="true">MRPWPLFISAPLLGLSHSILLVFTPIFIEKTTLSLASLAILMSLGSALFLFSAPMWAKCSLRYGYPKVLLSGILGFSTSFSLMLVALWGSVSLQWPMVWVISSLIISRVIYGMTASAIVPSCQAWLSELNHAEHTMKKLAELSATMAFGRLIAPLLAMALIWIGWQAPLLFLSLAPLICLGYILKFSRSQEPLPAPAAHQIDKPISVQDKIDDKSVHSLLISITLICISYSCVTFLLTPMAIQWLNYSNQQASQYLSLLMTLAAMTMLLCHGITSKLKQVDQFKMMLLANMMLLLSLILMQLPIPHILFICVPLLSGAFAILQLQITSLLCNQAGKGKKAIATGLVSKYQTLGYGIGAGLLWLTNSDIDTNLQLLTLLGLAQLASLMFWKFNIGTKEAVKDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF6</accession>
    <name>B1KRF6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2079</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324708.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2079"/>
    <dbReference type="EnsemblBacteria" id="ACA86363">
        <property type="protein sequence ID" value="ACA86363"/>
        <property type="gene ID" value="Swoo_2079"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2079"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064076_3_1_6"/>
    <dbReference type="OMA" id="FFPKFFY"/>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="34"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="30063" checksum="B6E2734D5F719394" modified="2008-04-29" version="1" precursor="true">MGLFRAFNWIAATIFLLVHMSLLAQERPARIVFSTSNYEPYVVNTKGVASGVIPDIIEEALKGSVFAPDIIFEPWLRGEHALKAGKVFACFPYLKTAERQGEFVFSDPLIYFFPKFFYLKSRFPNGFEWQKLSDFKGYTLGGVRGYWYEKQFKQAGLTIHYVTSDKQNIEMLKLKRVDFTLIDELVGWELVGQSFPKELASYEVASKPESSAAFHLMISHNYPNSKAITRTFNLGLRRIVENGTYQKILERYQVPQGYSVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRI1</accession>
    <name>B1KRI1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase class-I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324733.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2104"/>
    <dbReference type="EnsemblBacteria" id="ACA86388">
        <property type="protein sequence ID" value="ACA86388"/>
        <property type="gene ID" value="Swoo_2104"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2104"/>
    <dbReference type="eggNOG" id="COG0518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054974_0_2_6"/>
    <dbReference type="OMA" id="PWIQTLK"/>
    <dbReference type="OrthoDB" id="1242215at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="80"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="26301" checksum="FBDCFF2DFD15499D" modified="2008-04-29" version="1">MKIGILQCDDVTETLQAKHGNYPKMFTRLFEDIDAQLEFSVFRVMDGHYPSSVDDCDAYITTGSRFGVNDDEPWVVQFQHYIAKLFASKKKLIGICFGHQMMVKALGGEVVKSPKGWGVGVATSMVTQQKPWMNGLSSEISLVVSHQDQVVELPEGTEIIAASDFCPFYMIQVNDHFLGVQGHPEFSKQYSQDLMYARRDRIPKERIESGVESLSLPVDDKLVTRWMLNFLH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRP6</accession>
    <name>DEOB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphopentomutase</fullName>
            <ecNumber evidence="1">5.4.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphodeoxyribomutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">deoB</name>
        <name type="ordered locus">Swoo_3547</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Phosphotransfer between the C1 and C5 carbon atoms of pentose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-ribose 1-phosphate = D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:18793"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="5.4.2.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27658"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="5.4.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 1 or 2 manganese ions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphopentomutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326144.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRP6"/>
    <dbReference type="SMR" id="B1KRP6"/>
    <dbReference type="STRING" id="392500.Swoo_3547"/>
    <dbReference type="EnsemblBacteria" id="ACA87811">
        <property type="protein sequence ID" value="ACA87811"/>
        <property type="gene ID" value="Swoo_3547"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3547"/>
    <dbReference type="eggNOG" id="COG1015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053861_0_0_6"/>
    <dbReference type="OMA" id="YLGNCHA"/>
    <dbReference type="OrthoDB" id="1772797at2"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00173"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008973">
        <property type="term" value="F:phosphopentomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043094">
        <property type="term" value="P:cellular metabolic compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16009">
        <property type="entry name" value="PPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00740">
        <property type="entry name" value="Phosphopentomut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010045">
        <property type="entry name" value="DeoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024052">
        <property type="entry name" value="Phosphopentomutase_DeoB_cap_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21110">
        <property type="entry name" value="PTHR21110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001491">
        <property type="entry name" value="Ppentomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143856">
        <property type="entry name" value="SSF143856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01696">
        <property type="entry name" value="deoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000133100" description="Phosphopentomutase">
        <location>
            <begin position="1"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00740"/>
        </source>
    </evidence>
    <sequence length="405" mass="43727" checksum="2E23EBE86712B900" modified="2008-04-29" version="1">MKRTIIMMLDSFGVGAATDAESFGDVGSDTFGSIAKACAEGRADIGREGPLKLPNLSKLGLALAAKESTGTFAPGFSDDVEVIGAYGHADELSTGKDTPSGHWEMAGVPVLYEWGYFSDLTNSFPKELTDKILARAGLDGYLGNCHASGTAILEELGEEHMRTGKPIFYTSADSVFQIACHEESFGLENLYNLCIIAREELEPYNIGRVIARAFVGTGPSDFARTGNRRDYAVEPPSKTVLDKMKAAGGEVISVGKIADIYANCGITQKVKATGLEALFDATLEQVKAAGDKSIVFTNFVDFDSHYGHRRDIAGYAKALEYFDSRLPEIFEILGEDDLLLLTADHGCDPSWKGTDHTRERVPVLAYGAGLKAGSLGRRNSFADIGQSIASYFKLEPMEYGESFIK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRQ3</accession>
    <name>RF3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptide chain release factor 3</fullName>
            <shortName evidence="1">RF-3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prfC</name>
        <name type="ordered locus">Swoo_3554</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326151.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRQ3"/>
    <dbReference type="SMR" id="B1KRQ3"/>
    <dbReference type="STRING" id="392500.Swoo_3554"/>
    <dbReference type="EnsemblBacteria" id="ACA87818">
        <property type="protein sequence ID" value="ACA87818"/>
        <property type="gene ID" value="Swoo_3554"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3554"/>
    <dbReference type="eggNOG" id="COG4108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_2_1_6"/>
    <dbReference type="OMA" id="GFVFKIH"/>
    <dbReference type="OrthoDB" id="164090at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04169">
        <property type="entry name" value="RF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00072">
        <property type="entry name" value="Rel_fac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004548">
        <property type="entry name" value="PrfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041732">
        <property type="entry name" value="RF3_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43556">
        <property type="entry name" value="PTHR43556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00503">
        <property type="entry name" value="prfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000092501" description="Peptide chain release factor 3">
        <location>
            <begin position="1"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="9"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="18"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="140"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00072"/>
        </source>
    </evidence>
    <sequence length="526" mass="59308" checksum="154733CC736CA708" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD08</accession>
    <name>B1KD08_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2489 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322704.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0054"/>
    <dbReference type="EnsemblBacteria" id="ACA84355">
        <property type="protein sequence ID" value="ACA84355"/>
        <property type="gene ID" value="Swoo_0054"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0054"/>
    <dbReference type="eggNOG" id="ENOG50332QM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136762_0_0_6"/>
    <dbReference type="OMA" id="CNHSEGV"/>
    <dbReference type="OrthoDB" id="1731313at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019617">
        <property type="entry name" value="DUF2489"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10675">
        <property type="entry name" value="DUF2489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2489" evidence="2">
        <location>
            <begin position="13"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="155" mass="17669" checksum="9B96319C40408D98" modified="2008-04-29" version="1" precursor="true">MTTVLLILGFIIVASLACYATILILKLRKQTADRLAKQAELDAAHKAKLEEHLDSIRYIATAMLEDRCELSEGVMRIANLFNIISLSEQVANDYPAIFKHFAVIESHPIMAERKQLEKRARMKLDYARMRSEAELETEILQEAKQLTTFTPTPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD65</accession>
    <name>B1KD65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase FAD/NAD(P)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326233.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3638"/>
    <dbReference type="EnsemblBacteria" id="ACA87900">
        <property type="protein sequence ID" value="ACA87900"/>
        <property type="gene ID" value="Swoo_3638"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3638"/>
    <dbReference type="eggNOG" id="COG0543">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_7_4_6"/>
    <dbReference type="OMA" id="FDIYVCG"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="26866" checksum="FBE04706925A2AAD" modified="2008-04-29" version="1">MIIDCKISKIESAKNNIYKVYISPEQNIDFKAGQYIFIKLNDKKTPFSIANCPTENKIIELHIGSSNQDSSSTSIEYFVDALVNNSKFEIDAPHGEAWLRTNNYKPILLIAGGTGLSYINSILKNCLNRGFIQPIYLYWGVKNIDFLYADEELTQLSNKHCNLHYIPVIIEDEQAVWLGKKGTVIDAVMEDFTDLTPFDIYVCGPYQMAKAAKERLVSEKKANFEQMYADAFAYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDC0</accession>
    <name>B1KDC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323268.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0625"/>
    <dbReference type="EnsemblBacteria" id="ACA84921">
        <property type="protein sequence ID" value="ACA84921"/>
        <property type="gene ID" value="Swoo_0625"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0625"/>
    <dbReference type="eggNOG" id="ENOG5033MNG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162704_0_0_6"/>
    <dbReference type="OMA" id="QYLECNG"/>
    <dbReference type="OrthoDB" id="1899452at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767262" evidence="1">
        <location>
            <begin position="22"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="13960" checksum="E2D856B1D24D84D3" modified="2008-04-29" version="1" precursor="true">MKTWKISFLSLLLLSACSNLTFRTHISPEIGDVAARSIAASDVREFSVEEMSRREKEFLGEIRSSYCQAGLSKPSPSRSLLATDLRYKTVGLGGNGYTVMECFDSNAGCNAYLECRALAYTVRDGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDC6</accession>
    <name>B1KDC6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0631"/>
    <dbReference type="EnsemblBacteria" id="ACA84927">
        <property type="protein sequence ID" value="ACA84927"/>
        <property type="gene ID" value="Swoo_0631"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0631"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074108_1_0_6"/>
    <dbReference type="OMA" id="FCGANTL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="158"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="320" mass="35743" checksum="513F6A2F9ADF3E30" modified="2008-04-29" version="1">MQANFKLGFFFISTAVLFWGILPIALKLSASFIDPVTLTWFRFLVALLITFVIQYVSGSLKQFASLKSRDWLKLAFSGVFLMFNYVSFVYSLAYLAPGAAQLNFQTAPFFLAFGGMLFFKERLNAVQMACFATLALGMLLFFHPYLDFSQSDNSAIWIGVMIIQFSVCSWTSYALLQKSLLKKLDPNNILLFIYGLGVLVMAFFSDFTQFGVMTLNEWWVAIFCAINTLIAYGCFGASMKYWPTPQVSAMLALTPVLSFSATALVVSLGLWPNAFVSDELNLLSLSGIAIIILSVASLQLLPVMKKRREKYSSLSVNEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ0</accession>
    <name>B1KDJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323338.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0696"/>
    <dbReference type="ESTHER" id="shewm-b1kdj0">
        <property type="family name" value="A85-IroE-IroD-Fes-Yiel"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84991">
        <property type="protein sequence ID" value="ACA84991"/>
        <property type="gene ID" value="Swoo_0696"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0696"/>
    <dbReference type="eggNOG" id="COG2819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914967_0_0_6"/>
    <dbReference type="OrthoDB" id="1828423at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764719" evidence="1">
        <location>
            <begin position="22"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="304" mass="33981" checksum="402B12686DC854F9" modified="2008-04-29" version="1" precursor="true">MKWISAKQYLLAIAFSVSSLSTVGCSSTVKETSSSTDINSLVPLNFLPALAGDYFKLESESVGRPFHIYVRLPEGYDENKSKQYPVVYLLDGDSLFPILATNHLFLQYDDKLPEAIIVGIAYGSFDPSINKRGYDFSAPAVDAKPNQGGAPKFQQFLETELIPDIESRYQTDPNKRVLFGQSRGGYMVLYSAFTKPDLFWGHIASNPSIKPGRERFFSTPNSANRDDLSLILTSGSHDRGYSRDNAMDWSKEWQNRNDAPWDVKVFTIDGGTHAANSTDSYRLGINWLFHKEDTARDSAAIESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ9</accession>
    <name>B1KDQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324800.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2174"/>
    <dbReference type="EnsemblBacteria" id="ACA86456">
        <property type="protein sequence ID" value="ACA86456"/>
        <property type="gene ID" value="Swoo_2174"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2174"/>
    <dbReference type="eggNOG" id="COG1279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087840_0_1_6"/>
    <dbReference type="OMA" id="FARPRAW"/>
    <dbReference type="OrthoDB" id="1953934at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="21572" checksum="845B605503096BCA" modified="2008-04-29" version="1">MQAFIQGVGIGGSLIMAVGAQNAFVLKQGLKRSHSLPIAGLCSLIDALMITAGVAGLGHLILAFPLIKDIASIGGAIFLLVYGAKALQSSFIPHSLGDETSKGTDTLKAAVLTTLGISLLNPHLYLDTVVLLGSISAQFEGSDRPMFGAGAVLASFVWFFSLSFGARYLSPLFQKPKAWCYLDRFICATMWTIAGVLIWPYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU8</accession>
    <name>B1KDU8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326282.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87950">
        <property type="protein sequence ID" value="ACA87950"/>
        <property type="gene ID" value="Swoo_3690"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3690"/>
    <dbReference type="eggNOG" id="ENOG5033MEX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1824006_0_0_6"/>
    <dbReference type="OMA" id="AVKRNHW"/>
    <dbReference type="OrthoDB" id="1967249at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767274" evidence="1">
        <location>
            <begin position="23"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15636" checksum="88C10A909014F89F" modified="2008-04-29" version="1" precursor="true">MKKVIASLIIGLSSMAVFDAQAIHSYQDPVPFKGYVKDIGPLLEKVMKRNHWQLSKNDSGSYFADLNYKDYQVQAKLLVQDETLAIELISAQRPNCTKRSCKVDDDTVDDWLVRLRKQIALDVTKAVRDDALRKSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE20</accession>
    <name>B1KE20_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0711</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323353.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0711"/>
    <dbReference type="EnsemblBacteria" id="ACA85006">
        <property type="protein sequence ID" value="ACA85006"/>
        <property type="gene ID" value="Swoo_0711"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0711"/>
    <dbReference type="eggNOG" id="COG4987">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_6"/>
    <dbReference type="OMA" id="VSHNATF"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034775">
        <property type="term" value="P:glutathione transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014223">
        <property type="entry name" value="ABC_CydC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02868">
        <property type="entry name" value="CydC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="19"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="341"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="374"/>
            <end position="381"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="591" mass="65096" checksum="9889660797187208" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE80</accession>
    <name>B1KE80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323413.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0771"/>
    <dbReference type="EnsemblBacteria" id="ACA85066">
        <property type="protein sequence ID" value="ACA85066"/>
        <property type="gene ID" value="Swoo_0771"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0771"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141012_0_0_6"/>
    <dbReference type="OMA" id="RIFKMFI"/>
    <dbReference type="OrthoDB" id="1745184at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="184" mass="20873" checksum="66F77005E3D31882" modified="2008-04-29" version="1">MAKRSKAETEQTINLIMDEALKQLLSLGYDSMSYTTLSTATGISRTGISHHFPHKANFLIRLDPQISRLFLEELDFSNLGTLEESWIESIKHPTGRMVLKLFFSLCGDHCEDVIQFRAIHLARERAYEMFGLEGEKLVTGLIGRSAVMLMSQSTHIKVPQLQANELKTRNRGNTESRLAILSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE83</accession>
    <name>B1KE83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0774</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323416.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0774"/>
    <dbReference type="MEROPS" id="S54.027"/>
    <dbReference type="EnsemblBacteria" id="ACA85069">
        <property type="protein sequence ID" value="ACA85069"/>
        <property type="gene ID" value="Swoo_0774"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0774"/>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3809">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_796317_0_0_6"/>
    <dbReference type="OMA" id="MYLLWFR"/>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027392">
        <property type="entry name" value="TF_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13453">
        <property type="entry name" value="zf-TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="zf-TFIIB" evidence="7">
        <location>
            <begin position="5"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="zf-TFIIB" evidence="7">
        <location>
            <begin position="69"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="191"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="360" mass="39810" checksum="D306E2E89A3FFF34" modified="2008-04-29" version="1">MIMSCPGCNSSNMKVYDFHGEEVDSCQSCGGLWFENGELNAALSSADNGDSCVRVEESLGEHLGDSKRHCHHCDVGMQHYHLMQGYQIEVDVCHSCSGLWIDEDERVKVVQSPLVKSLLADLDAKISAKTWFFQFLSQMPVEFNLKPKSRPVVTYLLLALNILIFLAYGFDMSTTDTVFENFAMRSNEVLAGHQPWTLVSHMFLHGDFMHLVGNMYFLYVVGDNLEDALGRVKFLGVYLICGFAAAAAQIASDPGSGIYMVGASGAIAGLFGMYLLWFRHASLTFMFVVYQKKLSPMAFFAIWLGFNIFGLLMAGQGVAYWAHIGGFVAGLIIGAALKDRVMESNPILAMLNEPEVKVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB5</accession>
    <name>B1KEB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glucose/galactose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2211</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Intake of glucose and galactose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324837.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2211"/>
    <dbReference type="EnsemblBacteria" id="ACA86493">
        <property type="protein sequence ID" value="ACA86493"/>
        <property type="gene ID" value="Swoo_2211"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2211"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028452_2_2_6"/>
    <dbReference type="OMA" id="PVIREHS"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005354">
        <property type="term" value="F:galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005355">
        <property type="term" value="F:glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005964">
        <property type="entry name" value="Glc/Gal_transptr_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01272">
        <property type="entry name" value="gluP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="317"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="13">
        <location>
            <begin position="27"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="424" mass="44617" checksum="20950A0530EEA719" modified="2008-04-29" version="1">MASLYNNSQLDNSGSNKAGTEGSYRFALVSLTSLFFMWGFITCLNDILIPHLKAVFSLNYTQAMLIQFCFFGAYFLVSIPAGRLVKKLGYQKGIVTGLIIASLGCALFYPAAEFETYGLFLGALFVLASGITILQVAANPYVNALGSSETASSRLNLTQAFNALGTTVAPYFGAVLILSVATEATSALAHSAEAEVVKLPYLLLSGMLAVLALVFAKLKLPVIQSHIDLNSGETVTYKGRTGALQSTHLVLGAVGIFVYVGAEVSIGSFLVNFLGESHIGGLKESEAAQLITYYWGGAMVGRFIGSAVMQKVAAGKVLAFNAAMAAILVAVAMLSSGNIAMWAILAVGLFNSIMFPTIFSLALRDLGPHTSQGSGVLCLAIVGGAILPLLQGITADAIGIQQAFFLPILCYAFILFYGVKGSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KED4</accession>
    <name>B1KED4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324856.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2231"/>
    <dbReference type="EnsemblBacteria" id="ACA86512">
        <property type="protein sequence ID" value="ACA86512"/>
        <property type="gene ID" value="Swoo_2231"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2231"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092618_2_0_6"/>
    <dbReference type="OMA" id="WVIEGCY"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="18688" checksum="FFB54C1BA6D05D9E" modified="2008-04-29" version="1">MRRVIIFGNSGSGKSTLAKQLCESEGLAHLDLDTLAWQPMGDDQAPLRMPLHNSKQELERFIAEKDSWVIEGCYIDLVALVSDRATELIFMDLDVDKCIANARSRPWEPHKYESKDAQDANLVMLLEWISQYYHREDEFSHLSHNAFFGRYTGKKTRLIENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KED9</accession>
    <name>B1KED9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 12">Malate synthase G</fullName>
            <ecNumber evidence="10 12">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">glcB</name>
        <name evidence="13" type="ordered locus">Swoo_2236</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 12">
            <text>acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10 12">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 12">Belongs to the malate synthase family. GlcB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="10 12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324861.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2236"/>
    <dbReference type="EnsemblBacteria" id="ACA86517">
        <property type="protein sequence ID" value="ACA86517"/>
        <property type="gene ID" value="Swoo_2236"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2236"/>
    <dbReference type="eggNOG" id="COG2225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028446_1_0_6"/>
    <dbReference type="OMA" id="MAPGFDG"/>
    <dbReference type="OrthoDB" id="322024at2"/>
    <dbReference type="UniPathway" id="UPA00703">
        <property type="reaction ID" value="UER00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00641">
        <property type="entry name" value="Malate_synth_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006253">
        <property type="entry name" value="Malate_synthG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42739">
        <property type="entry name" value="PTHR42739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="Malate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="SSF51645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01345">
        <property type="entry name" value="malate_syn_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10 12" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0558">Oxidation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="10">
        <location>
            <begin position="127"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyoxylate binding" evidence="10">
        <location>
            <begin position="460"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 11">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 11">
        <location>
            <position position="635"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Cysteine sulfenic acid (-SOH)" evidence="10">
        <location>
            <position position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601465-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="725" mass="80103" checksum="4C9E6BA76CE3B9CC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEZ7</accession>
    <name>B1KEZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323495.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0853"/>
    <dbReference type="EnsemblBacteria" id="ACA85148">
        <property type="protein sequence ID" value="ACA85148"/>
        <property type="gene ID" value="Swoo_0853"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0853"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033692_0_0_6"/>
    <dbReference type="OMA" id="LFGIFDH"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="28"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="445" mass="51968" checksum="995452F5C1B793CC" modified="2008-04-29" version="1">MENRISVISVDKLFGFLNHKVEIKEEGVTFIHGPNGCGKTTFLKLIASFFEWDIANLNDTNFEQMCIEFQDEKKITIEKTIKVKKFENEEVKTPNFIFRLFKNNENIELYEFHRNPKEIRIPPSQLDEYLPFLHQIGPRRWVDGRTDEVLSYHEVIERFSHRLPFTGRKKRPEWLQSLQENAKLHFVQTQRLLKVNIENRAHRTEKNVTNVIEIYSDEIKNKISRLLAESSAVSQSKDRSFPQRLLSMYSIEALSEDKIRKDYDETEVKIEKLMEAGLIQQEKNLALPSKAFEATEKKVLTLYLQDINEKLAVFDDLLLRIETFLSIITKKLRNKSFKVSQQDGFFIETIQGEKQVLKPTQLSSGEQHEIVLFYELIFKTSDNSFFLIDEPEISLHIDWQRQFLSDISKIASLGQHSFLVATHSPQIIGTRRDLAVSLDGGILND</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF18</accession>
    <name>METK_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S-adenosylmethionine synthase</fullName>
            <shortName evidence="1">AdoMet synthase</shortName>
            <ecNumber evidence="1">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">metK</name>
        <name type="ordered locus">Swoo_0875</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="1">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323516.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KF18"/>
    <dbReference type="SMR" id="B1KF18"/>
    <dbReference type="STRING" id="392500.Swoo_0875"/>
    <dbReference type="EnsemblBacteria" id="ACA85169">
        <property type="protein sequence ID" value="ACA85169"/>
        <property type="gene ID" value="Swoo_0875"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0875"/>
    <dbReference type="eggNOG" id="COG0192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041802_1_1_6"/>
    <dbReference type="OMA" id="MPYLRPD"/>
    <dbReference type="OrthoDB" id="1024388at2"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0554">One-carbon metabolism</keyword>
    <keyword id="KW-0630">Potassium</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000093085" description="S-adenosylmethionine synthase">
        <location>
            <begin position="1"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="164"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="231"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="246"/>
            <end position="247"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <sequence length="384" mass="41701" checksum="4366554E5B418DD0" modified="2008-04-29" version="1">MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEVTTSAWVDIEEITRNTVREIGYTHSDMGFDADSCAILNVIGKQSPDINQGVDRADPKEQGAGDQGLMFGYANNETDVFMPAPITYSHMLVKRQSEVRKDKTLPWLRPDAKSQVTFAYNSDGSIAGIDAVVLSTQHSEDVTQADLIEGVMESIIKPVLPAKWLSKETKYFINPTGRFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCELQVSYAIGVAEPTSISIETFGTAKVAEELLIDLVRRHFDLRPYGLTEMLNLARPIYKSTAAYGHFGREEFPWEATDKVEALRADAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF27</accession>
    <name>B1KF27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome c, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323525.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0884"/>
    <dbReference type="EnsemblBacteria" id="ACA85178">
        <property type="protein sequence ID" value="ACA85178"/>
        <property type="gene ID" value="Swoo_0884"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0884"/>
    <dbReference type="eggNOG" id="ENOG50320QR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063015_0_0_6"/>
    <dbReference type="OMA" id="MHQVFHS"/>
    <dbReference type="OrthoDB" id="804993at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010181">
        <property type="entry name" value="CGCAxxGCC_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09719">
        <property type="entry name" value="C_GCAxxG_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767299" evidence="1">
        <location>
            <begin position="32"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="273" mass="28608" checksum="846198D3786532E9" modified="2008-04-29" version="1" precursor="true">MTINRRQALTRIIGISTAAAGVSLVGTSAFAATDDQGNFHLELGDKLKYVPLDPMATAKLAYETGGGCMHQVFHSLVTMLGNSSSADAAKFKTIPTALAGFGFAGVVGQGTICGNLNAAGMLINILDDINKQNSAVIGAAFRYYENTELPFSSPEFVSGIGSTDEKTALVGSSSTANSILCHSSISNWSKASGKTFSQKGERCYRLSASIAFHLVELLNRAYHGEDIAALPESKPSSDAQSCQSCHGVSDTMSSAASVKTDMECTTCHTGHFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF62</accession>
    <name>B1KF62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase</fullName>
            <ecNumber evidence="3">3.4.16.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324945.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2324"/>
    <dbReference type="MEROPS" id="S13.001"/>
    <dbReference type="EnsemblBacteria" id="ACA86603">
        <property type="protein sequence ID" value="ACA86603"/>
        <property type="gene ID" value="Swoo_2324"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2324"/>
    <dbReference type="eggNOG" id="COG2027">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017692_1_1_6"/>
    <dbReference type="OMA" id="DGTMRKR"/>
    <dbReference type="OrthoDB" id="720131at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00666">
        <property type="entry name" value="PBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766521" evidence="2">
        <location>
            <begin position="24"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="481" mass="52876" checksum="3B9E1A1D232BE67F" modified="2008-04-29" version="1" precursor="true">MCVIRHLTRAALLTCFISSPTLAEGYFSNLLSLIKPPHSHTALYAKNLVTDQVVFEENADTLLLPASTQKLLTAVAATAQLGDDFTFNTELYSRYPIRDGKVTGDLFLTFSGDPTLTTQDLRGLFKQLEDLGVSKINGDLYLVGDSNEQLQAPGWVWDDLGICFAAPVSQFVINQNCVHGQLKPMLASNKSQLSFASYLPVKFYNSAIFDKNKQETFCDLELKRLANNQFQLSGCYPGSKNIKLAVAISDPALFASDTLKQIIASSKIKLTGSVKLSNVSPNYANIIAKHSSQTLPQLLETMLLKSDNLIADSLLKQIGQSYYKSAGSFKNGSRAMREILTQAGVDLTHAQIVDGSGLSRYNLLSAKQLSQVLGLIYTDKRFMGLLDSLPLSGVSGTLQYKSYFNRKPLVNYVYAKTGSMQGVDNLAGFIKKPYFDDTLFVVLENGQSPLEKKEQIAPFSALFLQTLLDYEPSKVTSSLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK4</accession>
    <name>B1KFK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326509.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3921"/>
    <dbReference type="EnsemblBacteria" id="ACA88179">
        <property type="protein sequence ID" value="ACA88179"/>
        <property type="gene ID" value="Swoo_3921"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3921"/>
    <dbReference type="HOGENOM" id="CLU_1502483_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="20068" checksum="AC72366DC4B34800" modified="2008-04-29" version="1" precursor="true">MHVTDYKHWLAHLILTGFMLLVSGCSFNNFGIASESHIALYQHAKIVTNQASGLHIYTEPMLGIQLGHIEQRLVYPLLSTEHSVCIDQILDNTSKIDEPEKVQKYANTPVIVSSQKAGLGFSASPYHIRVDLGSSSRKTLRVDQKDSISIYYLNAAQKRDEDICAVLKIKPTDRDINDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY7</accession>
    <name>B1KFY7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325036.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2416"/>
    <dbReference type="EnsemblBacteria" id="ACA86694">
        <property type="protein sequence ID" value="ACA86694"/>
        <property type="gene ID" value="Swoo_2416"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2416"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_1_2_6"/>
    <dbReference type="OMA" id="MAKYQNM"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="4"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="175"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="310" mass="34511" checksum="75C5385E2CF652AE" modified="2008-04-29" version="1">MKEYKKLLVVVDPTSDTQPALARAVELATRNQASITVFLSIFDFSYEMTSILSGQEREAMRQGVIAQRQAWIDEVVEHYSTSEVTIESEVIWHNRPFESIIQHAISSEFDLIVKGTHEHDKLKSVIFTPTDWHLMRKSPVPVLLVKEHDWPVAGKILCAINVGSEDEDHISLNSKIVEHAKDLAKKFDAQVHLVNGYPGTPVNLAIELPDFDAHTYSETIRMQHEERVCELALTLGISTDNCHVKEGLPEDVIPDVAKKLDAELVILGTVGRTGFSAALIGNTAEHVIDSINCDLLAIKPDGYKSPLDES</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG52</accession>
    <name>LOLA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Outer-membrane lipoprotein carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lolA</name>
        <name type="ordered locus">Swoo_2482</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LolA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325101.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG52"/>
    <dbReference type="SMR" id="B1KG52"/>
    <dbReference type="STRING" id="392500.Swoo_2482"/>
    <dbReference type="EnsemblBacteria" id="ACA86759">
        <property type="protein sequence ID" value="ACA86759"/>
        <property type="gene ID" value="Swoo_2482"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2482"/>
    <dbReference type="eggNOG" id="COG2834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087560_0_0_6"/>
    <dbReference type="OMA" id="YDPFVEQ"/>
    <dbReference type="OrthoDB" id="1933827at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044874">
        <property type="term" value="P:lipoprotein localization to outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00240">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018323">
        <property type="entry name" value="OM_lipoprot_carrier_LolA_Pbac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35869">
        <property type="entry name" value="PTHR35869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03548">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00547">
        <property type="entry name" value="lolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0574">Periplasm</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5000316570" description="Outer-membrane lipoprotein carrier protein">
        <location>
            <begin position="23"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00240"/>
        </source>
    </evidence>
    <sequence length="208" mass="23185" checksum="1563B30CD67C735A" modified="2008-04-29" version="1" precursor="true">MRKTLTALMLSLPLLTPHMAFADESSVLKAKLTEIATLKAKFEQTVTDINNKQIQKGSGIFALAYPNQFYWHLTAPDESLIVADGTDVWIYNPFAEEVSVMDLNQAISASPIALLVHRDEETWSQYSVTSDNGCFNIKPKSIDAGVESVKVCFDDKTLTEMVLQDQQGNVSQFTLSEQTAIDDAERAMFKFTVPDDVDIDDQRLNAIN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG88</accession>
    <name>GCSH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gcvH</name>
        <name type="ordered locus">Swoo_3968</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="1">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326555.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG88"/>
    <dbReference type="SMR" id="B1KG88"/>
    <dbReference type="STRING" id="392500.Swoo_3968"/>
    <dbReference type="EnsemblBacteria" id="ACA88225">
        <property type="protein sequence ID" value="ACA88225"/>
        <property type="gene ID" value="Swoo_3968"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3968"/>
    <dbReference type="eggNOG" id="COG0509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097408_2_1_6"/>
    <dbReference type="OMA" id="YRDSHEW"/>
    <dbReference type="OrthoDB" id="1773485at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0450">Lipoyl</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000114551" description="Glycine cleavage system H protein">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="24"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01066"/>
        </source>
    </evidence>
    <sequence length="129" mass="13943" checksum="BFA03016B669F1F4" modified="2008-04-29" version="1">MSNIPAELKYASSHEWIRKEEDGSYTVGISEHAQELLGDMVFVELPEVGDTLSAGEDCAVAESVKAASDIYAPLSGEVLAVNEALEDSPELVNSDAFGDGWFFRVMPSDVAEIDNLLDAEGYQAVIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGD9</accession>
    <name>B1KGD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326605.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4020"/>
    <dbReference type="EnsemblBacteria" id="ACA88276">
        <property type="protein sequence ID" value="ACA88276"/>
        <property type="gene ID" value="Swoo_4020"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4020"/>
    <dbReference type="eggNOG" id="COG2333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052638_0_0_6"/>
    <dbReference type="OMA" id="SIWFNSS"/>
    <dbReference type="OrthoDB" id="1796527at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="10"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="34741" checksum="077DF6881FFFD25D" modified="2008-04-29" version="1">MKLIAFRALQGDSFLLQSGDTNILVDAGMPNTFGQISAALSGRSLTAVFISHVDYDHLGALFNLIKEAPILVKHSVFYMNTPHLATEYQGEEVGFKHGDSLQELLIKCNKSFQPLSKGRILDFKDIEIEVLWPTPSINEELYKNWNSSKILEENQYTYLKRQQNNGDIINKSSLVLLLSYKDNSILFLGDSHPETICKSLMDKGYSNTSPLKLDLLKLSHHGSKHNTSIELLRLIRCDNFYISTNGGKYGHPDKELIELIQSYAVESKKIINVYLNYDIEIDIKEKCTIELTMLKFKNQNELEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG8</accession>
    <name>B1KGG8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323643.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1003"/>
    <dbReference type="EnsemblBacteria" id="ACA85296">
        <property type="protein sequence ID" value="ACA85296"/>
        <property type="gene ID" value="Swoo_1003"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1003"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_0_6"/>
    <dbReference type="OMA" id="GKQMRPM"/>
    <dbReference type="OrthoDB" id="1861068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="35314" checksum="39ADBEE7774DC757" modified="2008-04-29" version="1">MDLNAIRQLADNDMQNVNKLIYKQLESDVALINQLGFYIINGGGKRMRPLLSILAARAVDYNGEAHLKLAAIIEFIHTASLLHDDVVDESMLRRGRETANALFGNSASVLVGDFLYTRSFQMMTELGSMEVLEVLADATNVLAEGEVLQLMNCNDPNTTEESYMRVIYCKTAKLFEAATRLAGVLADSPKEIQVALADYGKYLGTAFQLTDDLLDYTADTEELGKNIGDDLAEGKPTLPLIYAIAHGSETEQTLIRTAIEKGDGTDSIDPILAALDNCGALEYTYKRAQEEAEKAIGALSILPESDYKQALISLAKIAVARNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH72</accession>
    <name>B1KH72_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4234 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323726.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1087"/>
    <dbReference type="EnsemblBacteria" id="ACA85380">
        <property type="protein sequence ID" value="ACA85380"/>
        <property type="gene ID" value="Swoo_1087"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1087"/>
    <dbReference type="eggNOG" id="ENOG50339BW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1642573_0_0_6"/>
    <dbReference type="OMA" id="KAMHVIS"/>
    <dbReference type="OrthoDB" id="1769791at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025328">
        <property type="entry name" value="DUF4234"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14018">
        <property type="entry name" value="DUF4234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4234" evidence="2">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="18417" checksum="C95608EF49B8DFDE" modified="2008-04-29" version="1">MFINCSGKKMKNIKNIFHSNSIPKTITFCVLTFGIYVIYQLFTLTRIVNENVVNPIPQWFSISAITIHLISYFSLIIFFVASGSQELLIFSKAMHVISSIFHITWLIKVRNRINQIIGAKKGGDLWLNPILSSFLHVIYIQHKINQFLHKPISANSHTGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHA2</accession>
    <name>B1KHA2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323756.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1117"/>
    <dbReference type="EnsemblBacteria" id="ACA85410">
        <property type="protein sequence ID" value="ACA85410"/>
        <property type="gene ID" value="Swoo_1117"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1117"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068066_0_0_6"/>
    <dbReference type="OMA" id="YERQFDD"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="87"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="355" mass="39621" checksum="81A3346D003695B9" modified="2008-04-29" version="1" precursor="true">MKHPLNSLAIITSQLFAAGASAHNIHDIKFKPDGGYTSTVGAKYQAPNSQVNISADVKIDKLFERNMAGETLVQRITDRVYWVQNHFYNSLFFVGDKGVMVLDPLAYGAGRALLSAIKQVTDKPVTTLVYSHNHADHIGDAEVFVAEAKRQKVDLTILSSDATADKMKRLNSQLPRPTKTVDFNDGVYQFEDTRLKFIGFEHAAHTDDSAALLLVDEGVIHTPDLINPDQLPWLGFGGSENFTYYRQNLAKVSAQKWQYLSGGHGNIGSRADLDFMQHYLTDLNLAANRAMNRTDWAEFTTVENNNHAVFGAKWFEAASQDITNTLRPKYGHYYGFEASVPKQAELVLDTLLSYQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE1</accession>
    <name>RS21_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsU</name>
        <name type="ordered locus">Swoo_1156</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323795.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHE1"/>
    <dbReference type="SMR" id="B1KHE1"/>
    <dbReference type="STRING" id="392500.Swoo_1156"/>
    <dbReference type="EnsemblBacteria" id="ACA85449">
        <property type="protein sequence ID" value="ACA85449"/>
        <property type="gene ID" value="Swoo_1156"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1156"/>
    <dbReference type="eggNOG" id="COG0828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159258_1_0_6"/>
    <dbReference type="OMA" id="FKRSCQK"/>
    <dbReference type="OrthoDB" id="2088764at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018278">
        <property type="entry name" value="Ribosomal_S21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01181">
        <property type="entry name" value="RIBOSOMAL_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000120663" description="30S ribosomal protein S21">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <sequence length="71" mass="8331" checksum="DB6AF3EB4FCF5917" modified="2008-04-29" version="1">MPIIKVRDNEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAVKRLAKKLSRENARRVRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL8</accession>
    <name>B1KHL8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitrate/nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2626</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325243.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2626"/>
    <dbReference type="EnsemblBacteria" id="ACA86903">
        <property type="protein sequence ID" value="ACA86903"/>
        <property type="gene ID" value="Swoo_2626"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2626"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024204_4_1_6"/>
    <dbReference type="OMA" id="NSTYFAN"/>
    <dbReference type="OrthoDB" id="1217595at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015113">
        <property type="term" value="F:nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004737">
        <property type="entry name" value="NO3_transporter_NarK/NarU-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00886">
        <property type="entry name" value="2A0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="19"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="491" mass="53935" checksum="C3917A743EE4744A" modified="2008-04-29" version="1">MSNEGKMNLLNFADPKIKMLHVTWFAFFLSFVVWFSHAPLMVFIKEAFDLTSAQVKALLILNVALTIPARIVIGILVDKYGPRIIYSSLLIISSFICLGFAMAQSFEQLALFRFLLGFVGAGFVIGIRLVGEWFPAKQVGIAEGIYGGWGNFGSAAAAMSLPTLAYAFGGDDGWRYALACTGILAGLYGIFFYIAARNTPKGSTYFKPKKSGGLEVTSWKDFYFYLFMNIPMYIALAVLAWKLSPTGVNLFTTETMYIMWLSLLVLFFIQVNSIWRVNKENLTHGVPNIEKYEFKQVAILDVAYFVTFGSELAVVSMLPLFFLETFDGLDPVKAGLLASGFAFMNLVARPTGGWFSDKFGRRKSLMILVGGLAAGYAILSQVDGSWFIPLAVMATMVCSFFVQAGEGAVFAIVPLVKRRMTGQIAGMAGAYGNVGAVTYLTVLSFVDYSTFFLVISGSALFIFIATMFLNEPKGHMAEVNEDGTVELIDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS1</accession>
    <name>B1KHS1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4143</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326728.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4143"/>
    <dbReference type="EnsemblBacteria" id="ACA88399">
        <property type="protein sequence ID" value="ACA88399"/>
        <property type="gene ID" value="Swoo_4143"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4143"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_0_6"/>
    <dbReference type="OMA" id="ENHEYVA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="56"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="89"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="37430" checksum="64C5ECC80C81D40F" modified="2008-04-29" version="1">MRNSILIGCGVLVAACGDKAPDIPPPESRPAKLMTVTVSGEAEKRSFPALVVADDSAVLTFRVPGQLKQMQVKAGMQVTAGQTLAVLDQQELKLQLAQAQASYDLAKVQFERTAGLRKDFVVSEQDYEQAESKLNEAIANRDQAFANLGYATLHAPYDGAISLRHKENHEYVAANEPVMNIQTSDIVNVSFQLPERLAGQINRKQQTAIADIVFDTYPDKTFSAMLKQIDTEADRKTGSYKVTLTLKRPENVNVLPGMSTTVIVPIKAAVSSLIPKSALLKGNTDQHRVWQVGEDGRVSESLITLNDDRLIGGLQDGDVIVLSGVEYLNEGDKVTPWVKERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS5</accession>
    <name>B1KHS5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326732.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88403">
        <property type="protein sequence ID" value="ACA88403"/>
        <property type="gene ID" value="Swoo_4147"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4147"/>
    <dbReference type="eggNOG" id="ENOG50331H1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116739_0_0_6"/>
    <dbReference type="OMA" id="KISMRAR"/>
    <dbReference type="OrthoDB" id="1418537at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025982">
        <property type="entry name" value="SieB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14163">
        <property type="entry name" value="SieB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="22745" checksum="C17E80AD9B15317D" modified="2008-04-29" version="1" precursor="true">MQVLKSKNVKQLSSKQLSFNLMLWLAIVSGALLFMPKSLLQMLNLDTAVTANAHFIGLGLIIGVAYLLTQVLNYFLDEAITYLKGKRIIEVIEEKVRLLDPAERALLREFFLQGETILTLPQGEPAVKSLLAANIIESLGNQKHYAIQGPTADYKISMRARTYLNRQVLRLPVGEPSQEEMQNLIKARPTFANNMVSPRKHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT7</accession>
    <name>B1KHT7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4159</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326744.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4159"/>
    <dbReference type="ESTHER" id="shewm-b1kht7">
        <property type="family name" value="DPP4N_Peptidase_S9"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88415">
        <property type="protein sequence ID" value="ACA88415"/>
        <property type="gene ID" value="Swoo_4159"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4159"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019735_0_0_6"/>
    <dbReference type="OMA" id="TDWAHYN"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767071" evidence="1">
        <location>
            <begin position="23"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="3">
        <location>
            <begin position="378"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="631"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="827" mass="93608" checksum="B1573955BB8C84B8" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT8</accession>
    <name>B1KHT8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase of anthranilate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326745.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4160"/>
    <dbReference type="MEROPS" id="C26.955"/>
    <dbReference type="EnsemblBacteria" id="ACA88416">
        <property type="protein sequence ID" value="ACA88416"/>
        <property type="gene ID" value="Swoo_4160"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4160"/>
    <dbReference type="eggNOG" id="COG0512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_1_2_6"/>
    <dbReference type="OMA" id="TEHGHAM"/>
    <dbReference type="OrthoDB" id="1561172at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21351" checksum="F5EA8E7D022D36F7" modified="2008-04-29" version="1">MLLMIDNYDSFTFNLVQYFQQLGQEVVVKRNDEITLVDIEKLAPSHIIISPGPRSPNEAGISLAAIEHFAGKLPILGVCLGHQAIAQVFGAQVIRAKRVMHGKTSCINHLGKRLFKELKDPLTVTRYHSLLVGSLPKDFILDAWFDDEHCGREIMAMSHKHLPIYGVQFHPESVLTEQGHELLQNFLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB1</accession>
    <name>B1KIB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase T2 asparaginase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2686</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2686"/>
    <dbReference type="EnsemblBacteria" id="ACA86962">
        <property type="protein sequence ID" value="ACA86962"/>
        <property type="gene ID" value="Swoo_2686"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2686"/>
    <dbReference type="eggNOG" id="COG1446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021603_1_0_6"/>
    <dbReference type="OMA" id="YTYDGGH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="245"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="268"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="216"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="352" mass="37372" checksum="7686A5F8FE6A1F2F" modified="2008-04-29" version="1" precursor="true">MDTLMDHKIKITGLLLAILSSSTQVVADEKPFSIAIHGGAGTISKASLTPEQEQAYRDKLSQAVNAGYSILEKGGDSLVAIKAAINVLEDSPLFNAGVGAVYTFDGQHEMDASIMDGKTMNAGAVAGVKHIKNPINLADAVMNKSPHVMLSGAGAEEFALTQGFQLVPVAHFDTDKRYNQLIDAKEKIKTAETAKDYQAANHLMGRDYLDLDYKFGTVGAVALDQSGNLAAGTSTGGMTAKRFGRIGDSPVIGAGTYAENGVCAVSATGHGEYFIRYHVAGDICAKVKYQQKSIIQAADEVINQRLITAGGTGGVIALDQRGNIATPFNTEGMYRATRKNGEPVQVMIWRDK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC1</accession>
    <name>LFTR_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Leucyl/phenylalanyl-tRNA--protein transferase</fullName>
            <ecNumber evidence="1">2.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">L/F-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Leucyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phenyalanyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aat</name>
        <name type="ordered locus">Swoo_2696</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:12340"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12670"/>
            <dbReference type="Rhea" id="RHEA-COMP:12671"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:65249"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133043"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50416"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12673"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64719"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133044"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe) = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:43632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10637"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83561"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the L/F-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325311.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIC1"/>
    <dbReference type="SMR" id="B1KIC1"/>
    <dbReference type="STRING" id="392500.Swoo_2696"/>
    <dbReference type="EnsemblBacteria" id="ACA86972">
        <property type="protein sequence ID" value="ACA86972"/>
        <property type="gene ID" value="Swoo_2696"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2696"/>
    <dbReference type="eggNOG" id="COG2360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075045_0_0_6"/>
    <dbReference type="OMA" id="YRQGIFP"/>
    <dbReference type="OrthoDB" id="1670846at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00688">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042221">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="PTHR30098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03588">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00667">
        <property type="entry name" value="aat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000131953" description="Leucyl/phenylalanyl-tRNA--protein transferase">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00688"/>
        </source>
    </evidence>
    <sequence length="236" mass="26644" checksum="9B36449100E1AE3C" modified="2008-04-29" version="1">MNSLSYLNHELEQFPSPEFALTDPNGLLAVGGDLQPKRLLNAYYEGIFPWFNIDDPILWWSPDPRAVFVPGNMKTSRSLLKHLKKQPWRYSINHAFSQVIEGCAAPRSSQDGTWITPEIQDAYLKLHELGKAHSIEVWHQDELIGGLYGLATGQVFCGESMFHTQTNASKAAMLLLHQHLLKQGFKLIDAQVMNPHLASLGATALRRKDFINLLKRFRDLPVAADAWARSEVSLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIG6</accession>
    <name>B1KIG6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peroxiredoxin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2741</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325353.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2741"/>
    <dbReference type="EnsemblBacteria" id="ACA87017">
        <property type="protein sequence ID" value="ACA87017"/>
        <property type="gene ID" value="Swoo_2741"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2741"/>
    <dbReference type="eggNOG" id="COG0450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_21_1_6"/>
    <dbReference type="OMA" id="WWPKDFT"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="7">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="22030" checksum="FC8F9CADC3F2A7D0" modified="2008-04-29" version="1">MSVLVGRPAPDFTAAAVLGNGEIVDSFNLAEAIKGKPTVVFFYPLDFTFVCPSELIAFDHRIEEFKKRGVEVIGVSIDSQFTHNAWRNTPVAEGGIGPVQYTLVADVKHEICKAYDVEHPEAGVAFRGSFLIDKEGQVRHQVVNDLPLGRNVDEMLRMIDALQFHEEHGDVCPAGWEKGDKGMDASPEGVASYLNDNADTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK9</accession>
    <name>B1KIK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GtrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4249</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326832.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4249"/>
    <dbReference type="EnsemblBacteria" id="ACA88505">
        <property type="protein sequence ID" value="ACA88505"/>
        <property type="gene ID" value="Swoo_4249"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4249"/>
    <dbReference type="eggNOG" id="COG2246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083873_7_0_6"/>
    <dbReference type="OMA" id="GNRWLTF"/>
    <dbReference type="OrthoDB" id="1813832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15672" checksum="8986852423552993" modified="2008-04-29" version="1">MWQVGGLVVRVKGAFTLTQLKFLLVGGGSFVVDILLFLYLSQVLHWPISHARLMAFCVALLLTWIGNRLFTFSHRKRRPIGTQVLMAALLACCAACVNLSVFYLLSELREPSGLTGPVYLALGVLSGLVVNWLGSNLLVFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM4</accession>
    <name>B1KIM4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fumC</name>
        <name evidence="5" type="ordered locus">Swoo_4264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326847.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4264"/>
    <dbReference type="EnsemblBacteria" id="ACA88520">
        <property type="protein sequence ID" value="ACA88520"/>
        <property type="gene ID" value="Swoo_4264"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4264"/>
    <dbReference type="eggNOG" id="COG0114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021594_4_1_6"/>
    <dbReference type="OMA" id="RIATIWN"/>
    <dbReference type="OrthoDB" id="734949at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="11"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="4">
        <location>
            <begin position="402"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="133"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="318"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="458" mass="48684" checksum="DE199829DB2DC523" modified="2008-04-29" version="1">MTTRIEKDSMGELEVPASALYGAQTQRAVNNFPISGKTMPEPFIRALLLAKSAAAQANGKLGLLPLEMADGISGAVNQLLNEQNMMQHFPVDVFQTGSGTSSNMNANEVLATLASELTEQAVGANDHVNFGQSSNDIIPSCIHISAAIELDKQLLPGLRHLLQVIKSKANEVDRFVKTGRTHLMDAMPVRMSQSLLSWASQIEQNIELIEGIRPKLQSLAQGGTAVGTGINAHKEFAAEFSRQLSNVTGLAFTPADNFFSHIGTQDIAVSLSGQLKTTAVSMMKIANDLRWMNSGPLAGLGEIELEALQPGSSIMPGKVNPVIPEAAAMVAAQVIGNDSAITVGGQAGNFELNVMLPMIADNLLSSITLLANVSYLLADKAIASFKVNEAQLQKALARNPILVTALNPIIGYAKAAEIAKKAYKEGRAVLDVAEEETNISRDELERLLDPAKLTLGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIN3</accession>
    <name>B1KIN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4273</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326856.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4273"/>
    <dbReference type="EnsemblBacteria" id="ACA88529">
        <property type="protein sequence ID" value="ACA88529"/>
        <property type="gene ID" value="Swoo_4273"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4273"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546160_0_0_6"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="38"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="115"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="159"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="236"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="280"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="407"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="499" mass="54810" checksum="CF0D6F1B282724DB" modified="2008-04-29" version="1">MTKFLKNLFSSSKKQTTDNSSSEKLKEQKMQEALSAAGNKAVENVLGQSVDAVIMIDGNNNVTFVNDAAIKMWGYRKEEVIGKNVKMLVPQELQSQHDGFVNKNRRTKEDIIVGTSRDVELVRKDGSKTWINLALSRLENEGEIGYVGFARDISAQRQANDTIQQVLEQALDGVVTIDSQNIVTFMNSAAENLWGITREEVIGKNVKMLVPSEIRSNHDALVNANRNTGINKIVGTSRDLDLIRVDGSTIQANLSLCKIEVGGNIGYTAFVRDITEAKLAQDAIDQTLEQALDSVISIDENNIVTLFNKAAEELWGYKREEVIGQNVKMLVPVELQAGHDGLVNANRNTGVNKIVGTVREVPVFCKDGSKKWGSLSLSKVEVSGRILYTAFVRDVTEEVEMRDGMNEIMANVAKSSNEIADIAKVIDGISNQTNLLALNAAIEAARAGEHGRGFAVVADEVRQLASRSSESVTEINKLSEETQRFLKDLAINLKLDNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIN8</accession>
    <name>B1KIN8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326861.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4278"/>
    <dbReference type="EnsemblBacteria" id="ACA88534">
        <property type="protein sequence ID" value="ACA88534"/>
        <property type="gene ID" value="Swoo_4278"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4278"/>
    <dbReference type="eggNOG" id="ENOG5032RE7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097150_0_0_6"/>
    <dbReference type="OMA" id="IFFTHSL"/>
    <dbReference type="OrthoDB" id="1906744at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="200" mass="23396" checksum="AF728DDAAF6C7707" modified="2008-04-29" version="1">MEDIVDSEKVRAEIEGQSIIEEYSKIVDAPLFHVSLSKFCIMFVMTFGLYQLYWAFKQWQALRNFYQLDAWPVARSFFSIFFTHSLFVYITEYIKETEREYSWHQTGYATLYVFLVVVGSLFSNLIDEDSTNILLWSLTFVIPMMVVLPLYKAQKAINFALETVSYSSNDKLTLFNWLWIILGTAYWGLIVFSLVIIALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU2</accession>
    <name>B1KIU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pilin biogenesis protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323936.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1298"/>
    <dbReference type="EnsemblBacteria" id="ACA85590">
        <property type="protein sequence ID" value="ACA85590"/>
        <property type="gene ID" value="Swoo_1298"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1298"/>
    <dbReference type="eggNOG" id="COG3419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004773_0_0_6"/>
    <dbReference type="OMA" id="NQGLVHM"/>
    <dbReference type="OrthoDB" id="165468at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008707">
        <property type="entry name" value="PilC_beta_prop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05567">
        <property type="entry name" value="Neisseria_PilC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764923" evidence="1">
        <location>
            <begin position="24"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="domain" description="Neisseria_PilC" evidence="2">
        <location>
            <begin position="703"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1186" mass="127123" checksum="46AC3D5D81559D78" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ62</accession>
    <name>B1KJ62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325418.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2807"/>
    <dbReference type="EnsemblBacteria" id="ACA87082">
        <property type="protein sequence ID" value="ACA87082"/>
        <property type="gene ID" value="Swoo_2807"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2807"/>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_1_6"/>
    <dbReference type="OMA" id="LYKNCKH"/>
    <dbReference type="OrthoDB" id="1094814at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021812">
        <property type="entry name" value="DUF3391"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11871">
        <property type="entry name" value="DUF3391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="148"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="170"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="419" mass="47539" checksum="E873E6A36B73D9FF" modified="2008-04-29" version="1">MKKSVKVSVEELQIGNFVKLPVSWKDHPFLFSSFKLKQDAQIELIKRLGISHVFIDIERSEVQLDTEQPVQAPTPPKAANDLDSLAEEMSQYKNERIDVHQKMRRQLRKTEQEFDRSVSKMRSVVSKLRSRPLNAVNDAKELIHDMSEQLLNSDNLVLHLMGDAKDDEGIYYHSLNVAILSMLMAKELGWSRTDIELVGIGSLFHDTGKLKVPASILKKKTPLTPPEKNFFKQHPVMGEKILQLAENFPSEAIPIILNHHEHLDGSGFPRGLKEASLDKLSQLVAVINTYDMLCHPDAHSKPRTPYAALGYMFKHFKTKLNQQYTGSLIKMLGIYPPGSIVELSSGQFAMVMAVNLNKLLFPRILAYDAMIPKEQAPIVDLETEGLTIVRCIPHSALPEKVYKYLNPRERVSYFFGQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ65</accession>
    <name>B1KJ65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325421.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2810"/>
    <dbReference type="EnsemblBacteria" id="ACA87085">
        <property type="protein sequence ID" value="ACA87085"/>
        <property type="gene ID" value="Swoo_2810"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2810"/>
    <dbReference type="eggNOG" id="ENOG5033JPF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139110_1_0_6"/>
    <dbReference type="OMA" id="GVHIRFS"/>
    <dbReference type="OrthoDB" id="1878448at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="121" mass="13570" checksum="75F0A334D3B412C3" modified="2008-04-29" version="1">MLTKILITALIIVGALFYLRKPPASVKSQGTSKLGQQMMFRYLVYGLIATSLLASGGYWYWNWQDGNQVVSVTIVSPLEESSETYQVRKKDILANEITTLDGLSIRLSNQERVIIAKSIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJF7</accession>
    <name>B1KJF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326955.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4377"/>
    <dbReference type="CAZy" id="CBM57">
        <property type="family name" value="Carbohydrate-Binding Module Family 57"/>
    </dbReference>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88629">
        <property type="protein sequence ID" value="ACA88629"/>
        <property type="gene ID" value="Swoo_4377"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4377"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_582524_0_0_6"/>
    <dbReference type="OrthoDB" id="1046649at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021720">
        <property type="entry name" value="Malectin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11721">
        <property type="entry name" value="Malectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="187"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="469" mass="53557" checksum="2B0FC27021A398DC" modified="2008-04-29" version="1" precursor="true">MDRNQKYLTILKLTFCLSLLSGCSEYTHKNQSTTVPSKQDSYHSSPQILKGHHDTSATVWALNLGGPEYQGIDGVRYQADSLSPPDEIRRMNKVFGTQYQHLYQTYRVGDIKIRRPMTNGLYDITFKFAEPEDIPIGARVFDVLAQGKPVIENLDVRQARDGKHSSALSRTVTDVEITSGQLDIQLVSTQGQPILNAILVSKKQPKSNKWKFVWGDEFNYKGRPDNTKWNLDIWPARKVNDEDQAYTARPENIEVNGGNLVITARKENYANAEYTSARIHAKGKGDFLYGRAEIRAKIPAGQGTWSAIWMLPSDPYKYASSCKKDEEWQGSSSCDAWPNSGEIDIMEHVGFDMQNVHGTVHNRAYYWVNWQQRKGSIEAKNVEQEFHVYAMEWTPEKITIFFDDTPYFTYSNELTGWEAWPFDHPYHIILNLAVGGMWGRAGGPIDDSIFPVKMEVDYVRVYQQLNDTP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-12-15" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJV7</accession>
    <name>NUOK_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit K</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit K</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoK</name>
        <name type="ordered locus">Swoo_2869</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 4L family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325480.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJV7"/>
    <dbReference type="SMR" id="B1KJV7"/>
    <dbReference type="STRING" id="392500.Swoo_2869"/>
    <dbReference type="EnsemblBacteria" id="ACA87144">
        <property type="protein sequence ID" value="ACA87144"/>
        <property type="gene ID" value="Swoo_2869"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2869"/>
    <dbReference type="eggNOG" id="COG0713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144724_0_1_6"/>
    <dbReference type="OMA" id="NFVAFSY"/>
    <dbReference type="OrthoDB" id="2081663at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01456">
        <property type="entry name" value="NDH1_NuoK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001133">
        <property type="entry name" value="NADH_UbQ_OxRdtase_chain4L/K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11434">
        <property type="entry name" value="PTHR11434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000390235" description="NADH-quinone oxidoreductase subunit K">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="4"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01456"/>
        </source>
    </evidence>
    <sequence length="100" mass="11046" checksum="3F849DC289C52337" modified="2008-04-29" version="1">MIDTTWVIILSFLLFAIGTFGLLSRRNLLFILLSLEIMLNGIILLFIAASNLHGNNDGQIMYLLVLTLAASEVAVGLALVVQIYKQQQNLDVDTLTKLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK04</accession>
    <name>B1KK04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325527.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2918"/>
    <dbReference type="EnsemblBacteria" id="ACA87191">
        <property type="protein sequence ID" value="ACA87191"/>
        <property type="gene ID" value="Swoo_2918"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2918"/>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_1_6"/>
    <dbReference type="OMA" id="HTIYGYQ"/>
    <dbReference type="OrthoDB" id="1094814at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021812">
        <property type="entry name" value="DUF3391"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11871">
        <property type="entry name" value="DUF3391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="122"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="390" mass="43767" checksum="E27A93E9CE342054" modified="2008-04-29" version="1">MIVEQDISNVRVGMYVLDITYPKGKFHLTKASWLESEGVIENLRSKGVLRVLIDTSKTRDEPLSALSLVIESTAPSFTQQVEKARQIFDESKNIQKKLFHAAKNGFSLDLNSVSKVTDESIEIIFNNPDALSCVLNIRHKDEYLLEHSVAVSVLITMFAFHMKLEREIVSQLAIGAFLHDVGKIMVPDAILNKPGKLTDNEFNIMKSHATHSINTIKKTPGVSALSLEVAAQHHEKLNGEGYPNGLKSNEISIYGRMISICDIFDALTSSRCYKKGYSQVKAFSILRALAKENQLDADLVDNFIQCLGVYPVGAIVQLDSNRLAIVESHNKKNPVRPKVKAFYRLDPKQFEMAQNIDLASMETEHIVKCVRADEFDLNMEQIIEYLAREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK52</accession>
    <name>B1KK52_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GBBH-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327009.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4431"/>
    <dbReference type="EnsemblBacteria" id="ACA88683">
        <property type="protein sequence ID" value="ACA88683"/>
        <property type="gene ID" value="Swoo_4431"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4431"/>
    <dbReference type="eggNOG" id="COG3536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117841_0_1_6"/>
    <dbReference type="OMA" id="TAINLHK"/>
    <dbReference type="OrthoDB" id="2003927at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBBH-like_N" evidence="3">
        <location>
            <begin position="14"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14691" checksum="100C1180910BC3B6" modified="2008-04-29" version="1">MTTDPASPLVTNLKLKRKSRILEITFDSGDTHQISCEMLRVYSPSAEVHGHGNPVLVTHKKNVNIKALTPVGNYAVKIVFDDGHDTGLFSWKVLYDLATNQADLWENYLARLRAAKASREPLIDMAVKYHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKB4</accession>
    <name>B1KKB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324100.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1466"/>
    <dbReference type="EnsemblBacteria" id="ACA85754">
        <property type="protein sequence ID" value="ACA85754"/>
        <property type="gene ID" value="Swoo_1466"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1466"/>
    <dbReference type="eggNOG" id="ENOG50344HD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174840_0_0_6"/>
    <dbReference type="OMA" id="HAVYISI"/>
    <dbReference type="OrthoDB" id="1950661at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046034">
        <property type="entry name" value="DUF5992"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19454">
        <property type="entry name" value="DUF5992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764602" evidence="1">
        <location>
            <begin position="20"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="108" mass="11529" checksum="D54C268EE6246DB5" modified="2008-04-29" version="1" precursor="true">MNKIICLIILLFFSQQVTSGELVRGATIIEIASSSSNQDVFYLSLSGGTGPCAGKSILFPASKSQSKESYNQAFSIALAAAASGKKIRAHNYEDDSCREANFIGMLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD8</accession>
    <name>B1KKD8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324124.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1490"/>
    <dbReference type="EnsemblBacteria" id="ACA85778">
        <property type="protein sequence ID" value="ACA85778"/>
        <property type="gene ID" value="Swoo_1490"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1490"/>
    <dbReference type="HOGENOM" id="CLU_2002358_0_0_6"/>
    <dbReference type="OMA" id="FAKLFYS"/>
    <dbReference type="OrthoDB" id="1972019at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766760" evidence="1">
        <location>
            <begin position="20"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="13505" checksum="17CCC930FF984DDA" modified="2008-04-29" version="1" precursor="true">MKILILLVVSLLVSFSAQASAPACYSSYNGYCQYDGKVSRIYVNSSNLILLYFDEAMDPALGSEANMSLNSGVAAAVLITQNPEFAKLFYSTALAAQASQRNVQIQMRGTLSGYMKADRIWLAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP1</accession>
    <name>PDXB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Erythronate-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.290</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pdxB</name>
        <name type="ordered locus">Swoo_2987</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18829"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="ChEBI" id="CHEBI:58766"/>
            <dbReference type="EC" id="1.1.1.290"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.290" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325594.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKP1"/>
    <dbReference type="SMR" id="B1KKP1"/>
    <dbReference type="STRING" id="392500.Swoo_2987"/>
    <dbReference type="EnsemblBacteria" id="ACA87258">
        <property type="protein sequence ID" value="ACA87258"/>
        <property type="gene ID" value="Swoo_2987"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2987"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_4_0_6"/>
    <dbReference type="OMA" id="SAPGCNA"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033711">
        <property type="term" value="F:4-phosphoerythronate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12158">
        <property type="entry name" value="ErythrP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01825">
        <property type="entry name" value="PdxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020921">
        <property type="entry name" value="Erythronate-4-P_DHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024531">
        <property type="entry name" value="Erythronate-4-P_DHase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038251">
        <property type="entry name" value="PdxB_dimer_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11890">
        <property type="entry name" value="DUF3410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000188284" description="Erythronate-4-phosphate dehydrogenase">
        <location>
            <begin position="1"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01825"/>
        </source>
    </evidence>
    <sequence length="387" mass="43088" checksum="476736B1009A5655" modified="2008-04-29" version="1">MKIIADENMPYVQELFGDLGIIETVNGRSLTAEMVKDADVLLVRSVTQVDASLLSKNSQLTFVGSATIGTDHIDTEYLTQRQISFSNAPGCNATAVGEFAFIAMLELANRFGTSLKDKVVGIVGAGNTGSAVARCLQAYGVEVLLHDPLIEKSDPRNFVSLDELITRANVISLHVPITKSGEHKTWYLFDESRLNSLNADTWLLNCCRGEVVDNRALINVKQQRADIKVVLDVWEGEPNPMRELIPYVEFATPHIAGYSLEGKARGTYMLYQKLMQVLGKKEEKEMLALLPSFWTEQLTLTKEPSEKALLQLSRFVYDLRDDDALFRATLLEDPSKKAPVNSSNNNGFDLMRKNHKHRREFSALTLATTGQSEVDWLLNLGYSGVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKS0</accession>
    <name>B1KKS0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325623.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3016"/>
    <dbReference type="EnsemblBacteria" id="ACA87287">
        <property type="protein sequence ID" value="ACA87287"/>
        <property type="gene ID" value="Swoo_3016"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3016"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013133_6_0_6"/>
    <dbReference type="OMA" id="HGPYYTF"/>
    <dbReference type="OrthoDB" id="791272at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026032">
        <property type="entry name" value="HcaT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004925">
        <property type="entry name" value="HcaT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="203"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="389" mass="42636" checksum="11159677D9973E77" modified="2008-04-29" version="1">MNQTAQVSTQLRWISACYFFFFAILGVMVPYLGVFFENRGFNPQEIGFLLAILMATRIVAPNIWAMVADKTGMRAQLVKWGAAAAAVSYLTFFYNGSFTYLAISLTIYTFFWNAILAQLEVITLETLGENTSRYGAIRSFGSLGYLVFVVGVGFAISAWGTEVLPYVGMALFIGLLLSALPLPSDKVVTKKRAETPKLVLDKALFWFLLSATLLQMSAGPFYGFFVLYLKQSGYSEAVAGIYVAFGVLAEILMFMLAPRLLGRYGVNRLLIVSLGFTAVRWLLMAFFVESYLLLGVSQLLHAFTFGLVHAASIQFVHRHFDISHRSKGQALYASLSFGVGGALGTWLCGMIWGDGSGASLAWVVASVCAFIAMLAIFFIPGSDKRTGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW3</accession>
    <name>B1KKW3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327095.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4518"/>
    <dbReference type="MEROPS" id="S09.A77"/>
    <dbReference type="EnsemblBacteria" id="ACA88769">
        <property type="protein sequence ID" value="ACA88769"/>
        <property type="gene ID" value="Swoo_4518"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4518"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_3_1_6"/>
    <dbReference type="OMA" id="KHRWGGW"/>
    <dbReference type="OrthoDB" id="154149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765012" evidence="2">
        <location>
            <begin position="23"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="438"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="652" mass="72745" checksum="E1256E56E729BC2D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKX6</accession>
    <name>MURC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="1">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">murC</name>
        <name type="ordered locus">Swoo_4532</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327108.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKX6"/>
    <dbReference type="SMR" id="B1KKX6"/>
    <dbReference type="STRING" id="392500.Swoo_4532"/>
    <dbReference type="EnsemblBacteria" id="ACA88782">
        <property type="protein sequence ID" value="ACA88782"/>
        <property type="gene ID" value="Swoo_4532"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4532"/>
    <dbReference type="eggNOG" id="COG0773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028104_2_2_6"/>
    <dbReference type="OMA" id="DITYQLR"/>
    <dbReference type="OrthoDB" id="307881at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000091136" description="UDP-N-acetylmuramate--L-alanine ligase">
        <location>
            <begin position="1"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="128"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <sequence length="489" mass="53672" checksum="B43E36B629689DFF" modified="2008-04-29" version="1">MGNDKEKYSKLRNIIPEMRRVKHIYFVGIGGAGMGGIAEVLVNEGYRLSGSDIAENAVTQRLASLGAKIHLGHKEEQVHGADVVVVSTAIHADNPELLEAQALRIPVVRRAEMLAELMRYRHGVAVAGTHGKTTTTSLIASVYGQAERDPTFVIGGLLNSAGTNARLGNSRYLIAEADESDASFLHLQPMVSVITNIEADHMDTYEGDFERLKSTFIDFLHNLPFYGIAVMCIDDPVVRELLPSVGRKIVTYGFSEDADVQALNFVQDGYRSRFTLRRTGVEDVEVMVNLPGEHNVLNALAAIAVASEDEIEDEAIIQALADFEGIGRRFEQLGCFDTDRGEVVLVDDYGHHPSEVAATIKAAKLGWPEKRLVMIYQPHRYSRTRDLYEDFVEVLSQVDCLLLLDVYSAGEAAIPGADSRALCRSIRLRGQLDPIFVADQEQLLTLLPDVLQEGDLLLTQGAGNIGALARQLAQNRLGFESTNNDSNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL30</accession>
    <name>B1KL30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322720.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0070"/>
    <dbReference type="CAZy" id="GT9">
        <property type="family name" value="Glycosyltransferase Family 9"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84371">
        <property type="protein sequence ID" value="ACA84371"/>
        <property type="gene ID" value="Swoo_0070"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0070"/>
    <dbReference type="eggNOG" id="COG0859">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038371_2_0_6"/>
    <dbReference type="OMA" id="HMAVTQG"/>
    <dbReference type="OrthoDB" id="1326265at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="38086" checksum="0930755EEB402229" modified="2008-04-29" version="1">MSLNLNSITSLCLLRLSAIGDVCHAVAMVQAIQKQYPNLKITWVIGKVEYQLLKHLPGVEFVIFDKSQGWRSYFNLRKALAGQRFDVLLHMQVALRATIASLAISAKTRIGFDRARAKEGQWLVTNHRVDAIASPHVLEGFMGFAKTLGVTELTPQWNIPVPEADTEFAKLLLPDGERSLVICAAASKAERNWLPERYAAVAEHAIAKGYRVILCGGPTELEQTLAQQIVSHSSRPLENQVGKTTLTQLLAVLKQASIVLAPDTGPAHMAVTQGTPVIGLYAHSNPGRTGPYMSLEHVVSVYDKAIASQHSQPVVWGTRAKGEHLMEMIEVAPVLSVFDDLAREFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL70</accession>
    <name>B1KL70_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322760.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0110"/>
    <dbReference type="EnsemblBacteria" id="ACA84411">
        <property type="protein sequence ID" value="ACA84411"/>
        <property type="gene ID" value="Swoo_0110"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0110"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_4_1_6"/>
    <dbReference type="OMA" id="AYWFWNR"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="162"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="35524" checksum="14BFD2E530019C9F" modified="2008-04-29" version="1">MSNTQKGWLAAIFVGLLWGIPWIVGTPILEVMDPQVLVWLRYTVAFITLGLIFNIGLASGKMTKKADFKLNWQNRNDIFWAACCGIIGQGSFSFLSFLSLDYITASENGVIQGLIPILILSVGFLRHNERFTVMQMMCALGAFLGVAILVMDPQSETQGFNIGHLICFGSAASFACMAYARAKLAEKYGSVATMFHQFVFASLGFGLYLFVVGADFSSALNVFSSPLRIMCIVILGVCISGMSYLVYIYGMERVGVDGTGMALNLMPLSSFILAVFALGEQVTPMRLVAIAVVITSMIAFMKLGNQKKDKPVEQAALNTTKPCRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL86</accession>
    <name>B1KL86_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322776.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0126"/>
    <dbReference type="EnsemblBacteria" id="ACA84427">
        <property type="protein sequence ID" value="ACA84427"/>
        <property type="gene ID" value="Swoo_0126"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0126"/>
    <dbReference type="eggNOG" id="COG0824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091107_1_0_6"/>
    <dbReference type="OMA" id="RDIDMCH"/>
    <dbReference type="OrthoDB" id="1989068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="176" mass="21007" checksum="2226577BD5DC573E" modified="2008-04-29" version="1">MNLYFRLFWLFVWRVRHCNSIGFLGTSRIAYRALPCDCDINFHVTNSRYPAFLDLARTYMLAEMGFLNRFIKLKWMPIVNAAEFTYIRDIKPFTKFEIETRLVGWDEKYFYIEQRFVSDNTLHCIVHVRGVFVCKGKQVPIDTMVKEVNFEGPAPELPAEVVKWKEFLQLKKEQNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD6</accession>
    <name>B1KLD6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MAF_flag10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324207.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1575"/>
    <dbReference type="EnsemblBacteria" id="ACA85861">
        <property type="protein sequence ID" value="ACA85861"/>
        <property type="gene ID" value="Swoo_1575"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1575"/>
    <dbReference type="eggNOG" id="COG2604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_340603_0_0_6"/>
    <dbReference type="OMA" id="VGPTVTN"/>
    <dbReference type="OrthoDB" id="724933at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002826">
        <property type="entry name" value="MptE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01973">
        <property type="entry name" value="MAF_flag10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="MAF_flag10" evidence="2">
        <location>
            <begin position="175"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="788"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="833" mass="95124" checksum="B6D83E60E66485E0" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE6</accession>
    <name>B1KLE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324217.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1585"/>
    <dbReference type="EnsemblBacteria" id="ACA85871">
        <property type="protein sequence ID" value="ACA85871"/>
        <property type="gene ID" value="Swoo_1585"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1585"/>
    <dbReference type="eggNOG" id="COG4552">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1007942_0_0_6"/>
    <dbReference type="OrthoDB" id="1832083at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="276" mass="31358" checksum="033D975A0C651A59" modified="2008-04-29" version="1">MNILDEISFIDIENTSQLLMHYDGIAALFLESFDKELNCDLWKWAYLDNPFGEPLVSIAIHDNKIIGHYAVIPMNLENSSSSMLGFLSMTTMVAVDYRKHRLFQLLAERVYKKIESLNEPAIVFGFPNDNSVPGFKKRLGWTVSEEYKVITLQADMIDLAVIQLNQHIDSSSFTLNLSQEKVCNWRTSKPNQTWSYDKNIGLKALDDGFDVMHLSTAPSLNLAKSMSSINLILPVSEEFLANSGCEVAFAYRFGYRTFNTSSEPKIFVQMSMSDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG4</accession>
    <name>B1KLG4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Flagellar L-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Basal body L-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">flgH</name>
        <name evidence="11" type="ordered locus">Swoo_1603</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the FlgH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324235.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1603"/>
    <dbReference type="EnsemblBacteria" id="ACA85889">
        <property type="protein sequence ID" value="ACA85889"/>
        <property type="gene ID" value="Swoo_1603"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1603"/>
    <dbReference type="eggNOG" id="COG2063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069313_0_2_6"/>
    <dbReference type="OMA" id="ITQQPMT"/>
    <dbReference type="OrthoDB" id="1900876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009427">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, L ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00415">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000527">
        <property type="entry name" value="Flag_Lring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34933">
        <property type="entry name" value="PTHR34933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02107">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01008">
        <property type="entry name" value="FLGLRINGFLGH"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008947927" description="Flagellar L-ring protein" evidence="10">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="24795" checksum="B7E5826BD72C508D" modified="2008-04-29" version="1" precursor="true">MNKYWLWTVSSLVLLPVLAGCASTGGKPIADDPYYAPVYPEAPPTKIAATGSMYQDSQASSLYSDIKALKVGDIITVILMEQTQAKKSANNEIKKGTDLSLDPIYAGGGNISIGGQPIDLRYSDSMNTKRESGADQSNSLSGSISANVMQVLNNGNLVIRGEKWISINNGDEFVRLTGIVRSQDIRPDNTIDSPRVANARIQYSGTGTFADVQKVGWLSSFFMGSWWPF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG5</accession>
    <name>FLGI_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flagellar P-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Basal body P-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">flgI</name>
        <name type="ordered locus">Swoo_1604</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FlgI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324236.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLG5"/>
    <dbReference type="SMR" id="B1KLG5"/>
    <dbReference type="STRING" id="392500.Swoo_1604"/>
    <dbReference type="EnsemblBacteria" id="ACA85890">
        <property type="protein sequence ID" value="ACA85890"/>
        <property type="gene ID" value="Swoo_1604"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1604"/>
    <dbReference type="eggNOG" id="COG1706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045235_1_0_6"/>
    <dbReference type="OMA" id="KTIQITR"/>
    <dbReference type="OrthoDB" id="693640at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009428">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, P ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00416">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001782">
        <property type="entry name" value="Flag_FlgI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30381">
        <property type="entry name" value="PTHR30381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02119">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01010">
        <property type="entry name" value="FLGPRINGFLGI"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0975">Bacterial flagellum</keyword>
    <keyword id="KW-0574">Periplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5000317095" description="Flagellar P-ring protein">
        <location>
            <begin position="21"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00416"/>
        </source>
    </evidence>
    <sequence length="363" mass="38158" checksum="A33E6CA076217F6F" modified="2008-04-29" version="1" precursor="true">MKLKLFLLSVLLLVSGSSQAQRIKDIANVQGVRSNQLIGYGLVVGLPGTGEKTTYTEQTFKTMLKNFGINLPDNLRPKIKNVAVVAVHAEMPAFIKPGQTLDVTVSSLGEAKSLRGGTLLQTFLKGVDGNVYAIAQGSMVVSGFSAEGLDGSKVIQNTPTVGRIPNGGIVERTVTTPFSTGDHLTFNLRRADFSTAKRLADAINELLGPGMARPLDAASVQVSAPRDVSQRVSFLATLENIQVEPASESAKVIVNSRTGTIVVGREVRLLPAAVTHGGLTVTIAEATQVSQPNPLAGGQTVVTADTTIDVAEEDSRMFLFNPGTTLDELVRAVNLVGAAPSDVLAILEALKMAGALHGELIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH5</accession>
    <name>B1KLH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sigma54 specific transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324246.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1614"/>
    <dbReference type="EnsemblBacteria" id="ACA85900">
        <property type="protein sequence ID" value="ACA85900"/>
        <property type="gene ID" value="Swoo_1614"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1614"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_7_6"/>
    <dbReference type="OMA" id="LNYPQLT"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010518">
        <property type="entry name" value="FleQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06490">
        <property type="entry name" value="FleQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="5">
        <location>
            <begin position="134"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="477" mass="53865" checksum="D257E877C523C060" modified="2008-04-29" version="1">MMQTDQRILLVGNQSERMNRLSCVFEFLGEQVELVAVDKLELRVHNTRFRALIISSDIQSKELLQTLAATLPWQPILLLGEMDGAVASNILGHIEEPLNYPQLTELLHFCQVFGQAKRPDIPTSVNQTKLFRSMVGRSDGIAQVRHLINQVAPSDATVLVLGQSGTGKEVVARNIHYISDRRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISARKGRFELAEKGTLFLDEIGDMPLQMQVKLLRVLQEKVFERVGGSKSITTDVRVVAATHRQLESMILEGEFREDLYYRLNVFPIEMPALCERKDDIPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPVKYRHIDVPEYCVEVSEEEQERDALASIFNSDEPVDIPETRFPSELPPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLM2</accession>
    <name>B1KLM2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Anaerobic ribonucleoside-triphosphate reductase-activating protein</fullName>
            <ecNumber evidence="12">1.97.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_3048</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-[protein] + reduced [flavodoxin] + S-adenosyl-L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[protein] + H(+) + L-methionine + semiquinone [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:61976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:14480"/>
            <dbReference type="Rhea" id="RHEA-COMP:15993"/>
            <dbReference type="Rhea" id="RHEA-COMP:15994"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29947"/>
            <dbReference type="ChEBI" id="CHEBI:32722"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:140311"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.-" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325655.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3048"/>
    <dbReference type="EnsemblBacteria" id="ACA87319">
        <property type="protein sequence ID" value="ACA87319"/>
        <property type="gene ID" value="Swoo_3048"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3048"/>
    <dbReference type="eggNOG" id="COG0602">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089926_2_1_6"/>
    <dbReference type="OMA" id="NQVIHYL"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012837">
        <property type="entry name" value="NrdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF2">
        <property type="entry name" value="PTHR30352:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000368">
        <property type="entry name" value="NrdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00299">
        <property type="entry name" value="anaerobic_ribonucleoside-triph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02491">
        <property type="entry name" value="NrdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="17666" checksum="271EEA1DC0DE4C81" modified="2008-04-29" version="1">MNYHQYFPVDVVNGPGTRATLFVSGCEHQCRGCYNQSTWNPCHGHAFDEQMQDQVLRHLKDTRIKRRGLSLSGGDPLFPGNLTAILALVKRVKTQCPEKDIWLWSGYRLDELSEAQKEVIAYVDVLVDGKFEQALADPSLEFRGSSNQVIHYLGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM23</accession>
    <name>B1KM23_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4653</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327227.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4653"/>
    <dbReference type="EnsemblBacteria" id="ACA88903">
        <property type="protein sequence ID" value="ACA88903"/>
        <property type="gene ID" value="Swoo_4653"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4653"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_11_0_6"/>
    <dbReference type="OMA" id="LYYRDET"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766812" evidence="3">
        <location>
            <begin position="26"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="45"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="21434" checksum="7286A3F9782968B4" modified="2008-04-29" version="1" precursor="true">MKLIADLLKVSLLVASCFSISTVSAYPGMQKQAEGESQTNVGLISILPQPFPITAVPFKDEQGKAVDFSQYKGKVLMVNMWATWCPPCVRELPAISRLSEKFDKQDFEILPISIDLEGKGKVEPFLKELGMESFNSFYDETQNLREVFPLDTIPATFILNSKGELIAFVRTFVDWDDKQAADLIQGFIDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM26</accession>
    <name>B1KM26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome c-type biogenesis protein CcmF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4656</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327230.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4656"/>
    <dbReference type="EnsemblBacteria" id="ACA88906">
        <property type="protein sequence ID" value="ACA88906"/>
        <property type="gene ID" value="Swoo_4656"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4656"/>
    <dbReference type="eggNOG" id="COG1138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015041_3_0_6"/>
    <dbReference type="OMA" id="EFWLEDN"/>
    <dbReference type="OrthoDB" id="213184at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032523">
        <property type="entry name" value="CcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003567">
        <property type="entry name" value="Cyt_c_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003568">
        <property type="entry name" value="Cyt_c_biogenesis_CcmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017563">
        <property type="entry name" value="CytC_NO3Rdtase_biogenesis_NrfE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43653">
        <property type="entry name" value="PTHR43653"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16327">
        <property type="entry name" value="CcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01410">
        <property type="entry name" value="CCBIOGENESIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01411">
        <property type="entry name" value="CCMFBIOGNSIS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03145">
        <property type="entry name" value="cyt_nit_nrfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00353">
        <property type="entry name" value="nrfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="614"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="8">
        <location>
            <begin position="89"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="CcmF_C" evidence="9">
        <location>
            <begin position="315"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="659" mass="72821" checksum="2542F27595B2F003" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM43</accession>
    <name>B1KM43_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322805.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0155"/>
    <dbReference type="EnsemblBacteria" id="ACA84456">
        <property type="protein sequence ID" value="ACA84456"/>
        <property type="gene ID" value="Swoo_0155"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0155"/>
    <dbReference type="eggNOG" id="ENOG502ZXDZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1634252_0_0_6"/>
    <dbReference type="OMA" id="GQRIGQY"/>
    <dbReference type="OrthoDB" id="1751368at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="19016" checksum="5D6264FF1C877788" modified="2008-04-29" version="1">MLVVTNYPNVPIATTNAATDAARTDNLQRPPVIPPQEMTKGHEERPFTPQHERTAQHADVLARLNEKSQGKQQGTGQQQEDTKQQQQQAQPQQALMVKDLLKGKPALQRRDIRNNQYEMSANRNEGGKETRAPVLNQPSEVYQMFGQHIEAFYQGQTEPVTQSAISAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM50</accession>
    <name>B1KM50_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="4">3.1.1.61</ecNumber>
            <ecNumber evidence="4">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cheB</name>
        <name evidence="9" type="ordered locus">Swoo_0162</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CheB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="4"/>
    <dbReference type="EC" id="3.5.1.44" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322812.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0162"/>
    <dbReference type="EnsemblBacteria" id="ACA84463">
        <property type="protein sequence ID" value="ACA84463"/>
        <property type="gene ID" value="Swoo_0162"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0162"/>
    <dbReference type="eggNOG" id="COG2201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_51_0_6"/>
    <dbReference type="OMA" id="AMVKIRQ"/>
    <dbReference type="OrthoDB" id="1655418at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000876">
        <property type="entry name" value="RR_chemtxs_CheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="8">
        <location>
            <begin position="150"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4 6">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="340" mass="36850" checksum="B52030A9CCA9964A" modified="2008-04-29" version="1">MIKVLVVDDSPLVRQLLTHLLSDAPDIKVVGTAEDPYEAREQIKRLHPDVLTLDIEMPKMDGIAFLRNLMKLKPMPVIMVSTLTEKGAAVTLEALSIGAVDFILKPKSDLTSRLMEYREELIEKIHFASKSTIRPYTPIPKPSSDKQKSTYSRNKVIAIGASTGGTEAIQRLICQLPHDISPIVIAQHIPAAFSTSFAKRLNSNASMTVIEAQGGELLKPGTAYLAPGSAHLVVERKGMSLYTKLLDTDPVNRHRPSVDVLFDSVAESVGKSALGVILTGMGKDGAKGLLNMKNQGSFTVAQDEASSVVWGMPGAAVDIEASSEILHIDRIPQKILSLLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM58</accession>
    <name>CYOE1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protoheme IX farnesyltransferase 1</fullName>
            <ecNumber evidence="1">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Heme B farnesyltransferase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Heme O synthase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cyoE1</name>
        <name type="ordered locus">Swoo_0170</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322820.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KM58"/>
    <dbReference type="SMR" id="B1KM58"/>
    <dbReference type="STRING" id="392500.Swoo_0170"/>
    <dbReference type="EnsemblBacteria" id="ACA84471">
        <property type="protein sequence ID" value="ACA84471"/>
        <property type="gene ID" value="Swoo_0170"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0170"/>
    <dbReference type="eggNOG" id="COG0109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029631_0_2_6"/>
    <dbReference type="OMA" id="MYLKRAT"/>
    <dbReference type="OrthoDB" id="1875497at2"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0350">Heme biosynthesis</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000346017" description="Protoheme IX farnesyltransferase 1">
        <location>
            <begin position="1"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <sequence length="302" mass="33249" checksum="F9A20C2D08C59310" modified="2008-04-29" version="1">MAKPLSISSSDTQSQPLQWRAYYEMTKPKVVALMLLTVLVGMCLALPGAVPLQPLIFGLLGIGMMAGAAAAFNHLIDRRIDGLMARTYNRPLPKGRVSITKALTFSISLAVLGFVLLYTLVNELTAWLTFASLLGYAVVYTAYLKRATPQNIVVGGLAGAMPPLLGWTSVTGEFHGNALLLVIIIFAWTPPHFWALAIHRKAEYAKVDIPMLPVTHGTEFTKTCILLYTILLAIACLLPVLVGMCGPLYLVGSTLLSCGFIYKSWELKFDDKPGLAMQVFRFSIYHLMLLFIVLLVDHYLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM99</accession>
    <name>B1KM99_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetaldoxime dehydratase</fullName>
            <ecNumber evidence="1">4.99.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.99.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0211"/>
    <dbReference type="EnsemblBacteria" id="ACA84512">
        <property type="protein sequence ID" value="ACA84512"/>
        <property type="gene ID" value="Swoo_0211"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0211"/>
    <dbReference type="eggNOG" id="COG5485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065607_0_0_6"/>
    <dbReference type="OMA" id="FEYVGCH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018814">
        <property type="term" value="F:phenylacetaldoxime dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025702">
        <property type="entry name" value="Haem-containing_dehydratase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13816">
        <property type="entry name" value="Dehydratase_hem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="332" mass="38259" checksum="4AEFCABCA842AE0F" modified="2008-04-29" version="1">MMNNMPKNWTPPAPAWTSLWKTDEENLVCGLFAIQGQHSAPLDDWAKKAFTGEFSPKLLEQGMFTDKAGITNYLYIAYWFASDYKTWWQQSAANSWWASPLLDEGDISVWREVFTMPHQRFETLHSSENAHGAARLSPSLEGPMMEHGYSGAARDRIPCSSSQDIKNDNSIWEHLQVNVENKSNRIKLSPPKNMCVIRSGQDWTHCEEDEKEYYLTNVHTVLKKGMDYLSNNPVKTHCASMRFITKTDGNWCSVEQTFGLGYGNDIYAFENWAKSHPTHIAIFDRFMGMVEKYNVDLKLQLWHEVTLIPEQDCEFEYINCHGQTGLLCYINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMA9</accession>
    <name>B1KMA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaG subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322871.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0221"/>
    <dbReference type="EnsemblBacteria" id="ACA84522">
        <property type="protein sequence ID" value="ACA84522"/>
        <property type="gene ID" value="Swoo_0221"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0221"/>
    <dbReference type="eggNOG" id="COG3396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_879733_0_0_6"/>
    <dbReference type="OMA" id="MQPEANW"/>
    <dbReference type="OrthoDB" id="623539at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097266">
        <property type="term" value="F:phenylacetyl-CoA 1,2-epoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011881">
        <property type="entry name" value="PaaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02156">
        <property type="entry name" value="PA_CoA_Oxy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="317" mass="36450" checksum="7EF2928F1EB3C1B4" modified="2008-04-29" version="1">MNITENQASESLANFEHKIAEEQKIEPKDWMPEAYRANLIRQMSQHAHSEVIGMQPEGNWITRAPSLLRKMILLAKVQDEAGHGLYLYSATETLGVSREEMVSALHEKKAKYASIFNYPSLSWADIGAIGWLVDGAAIVNQISLQLTSYGPYARAMVKICKEESFHQRQGYNILIQLCEGTPEQKLMAQDSLNRWWWPSLMMFGPHDSESANSQKSMKWKIKRQSNDDLRQKFIDQTVEQAEFLGLTIPDPDLRWNEERGHYDFGEIDWNEFKKVISGDGHCNRDRIKHHQQAHKEGDWVRAAMTAYATKKSIKNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC1</accession>
    <name>B1KMC1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322883.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0233"/>
    <dbReference type="EnsemblBacteria" id="ACA84534">
        <property type="protein sequence ID" value="ACA84534"/>
        <property type="gene ID" value="Swoo_0233"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0233"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_13_3_6"/>
    <dbReference type="OMA" id="ANGEQSM"/>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009389">
        <property type="term" value="F:dimethyl sulfoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011888">
        <property type="entry name" value="Anaer_DMSO_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02166">
        <property type="entry name" value="dmsA_ynfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="8">
        <location>
            <begin position="41"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="838" mass="91340" checksum="0C6EF04A733FD129" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC9</accession>
    <name>B1KMC9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322891.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0241"/>
    <dbReference type="EnsemblBacteria" id="ACA84542">
        <property type="protein sequence ID" value="ACA84542"/>
        <property type="gene ID" value="Swoo_0241"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0241"/>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_1_3_6"/>
    <dbReference type="OMA" id="MAACPYH"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12800">
        <property type="entry name" value="Fer4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="24816" checksum="6C4FC1CFCEA293FD" modified="2008-04-29" version="1" precursor="true">MSNSRRLFLKGACVAAVGASGFTLVRAKEAGKNTSKPVYKYALVHDETKCIGCDACSIACREVNQVPEGVSRLEIKREGPFGEYPNQYFRFTRHSCQQCESTPCVDVCPTGAAYKDPDTGIVSVDEWKCVGCQYCIAACPYQIRFINPITKAADKCDFCKDTRLKEGKKPACVSACPTKALTFGDITDPDSQIVKVLKSAPSYRSKLDLGTRPKVFRIASQGGEVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME3</accession>
    <name>B1KME3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324287.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1655"/>
    <dbReference type="EnsemblBacteria" id="ACA85941">
        <property type="protein sequence ID" value="ACA85941"/>
        <property type="gene ID" value="Swoo_1655"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1655"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_6"/>
    <dbReference type="OMA" id="VRWMERI"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="19"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="342" mass="37887" checksum="5E759CEAC97E0C0C" modified="2008-04-29" version="1">MSRYEQIQQELIDSPKTWLVTGVAGFIGSNLLEKLLKLNQTVVGLDNFATGHQHNLDEVKSLVTEEQWERFTFIEGDIRDYSTCEESVKGVDYVLHQAALGSVPRSIADPITSNATNITGFLNMLQVAKAAKVESFTYAASSSTYGDHPALPKVEDNIGNPLSPYAVTKYVNELYANVFAKTYGFKTIGLRYFNVFGQRQDPNGAYAAVIPKWASAMIQGDEIFINGDGETSRDFCFIENTVQMNLLAATSEDIAKDEVYNVAVGDRTTLNDLFTNIQSSLNKSGSIYSIAPSYRAFRNGDVRHSQADISKAKQKLGYSPEFNISQGIAKAMPWYLGFLNNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH2</accession>
    <name>B1KMH2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324316.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85970">
        <property type="protein sequence ID" value="ACA85970"/>
        <property type="gene ID" value="Swoo_1685"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1685"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068226_2_1_6"/>
    <dbReference type="OMA" id="QIARYII"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="13"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="149" mass="17559" checksum="631FAD48140F3C31" modified="2008-04-29" version="1">MSWNDLRKGRFSQEQGEYFITFNTQNKQTYFNDFRIASIFCSQIAMSEHQHNCIWLTWVLMPDHFHGLLHLGNDSELSKIVGTLKGASSFAINKELKSSCKLWQSSFYDRALRYDDDRKSISRYIVANPLRKNLVKNIGNYPYWNSVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMM8</accession>
    <name>B1KMM8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal-dependent decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3135"/>
    <dbReference type="EnsemblBacteria" id="ACA87406">
        <property type="protein sequence ID" value="ACA87406"/>
        <property type="gene ID" value="Swoo_3135"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3135"/>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011856_0_4_6"/>
    <dbReference type="OMA" id="RHATYHA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022517">
        <property type="entry name" value="Asp_decarboxylase_pyridox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03799">
        <property type="entry name" value="NOD_PanD_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="551" mass="61167" checksum="94F2955B9712082B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP5</accession>
    <name>B1KMP5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325759.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3152"/>
    <dbReference type="EnsemblBacteria" id="ACA87423">
        <property type="protein sequence ID" value="ACA87423"/>
        <property type="gene ID" value="Swoo_3152"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3152"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066015_1_0_6"/>
    <dbReference type="OMA" id="YEKHYAR"/>
    <dbReference type="OrthoDB" id="1643157at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766867" evidence="1">
        <location>
            <begin position="22"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="286" mass="33318" checksum="39E3DCD4F9057A78" modified="2008-04-29" version="1" precursor="true">MRILTFFSPYILLFCALPVNAEPQVIRYNISDQFVDPKQSYYIDLLRLALEKSREPYGDYQLQAVVSEMAQARTVQLVQKGELDLVWTMTSIDRERRLTPVYFPLLKGLMGYRIAIIRRQDKQRFADIESVEELQVIPVGQGSDWPDSDILQKQGFTLVRGAARSLLSMLNMHRFDYFLRALHEPWDEVIGHPSLMIDSSFVIIYPSPIYFFVNPDDKRLAERVEYGLRNALLDGSFEALFNHHAITSQVIERANLPLRRIFTLDNPLLSQESKNLLSEKELWFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMR0</accession>
    <name>B1KMR0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3167</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325774.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3167"/>
    <dbReference type="EnsemblBacteria" id="ACA87438">
        <property type="protein sequence ID" value="ACA87438"/>
        <property type="gene ID" value="Swoo_3167"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3167"/>
    <dbReference type="eggNOG" id="COG0581">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017122_0_0_6"/>
    <dbReference type="OMA" id="FRWILAT"/>
    <dbReference type="OrthoDB" id="1763210at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="302"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="550" mass="61088" checksum="DF541526D20EF0E3" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN41</accession>
    <name>B1KN41_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327315.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88998">
        <property type="protein sequence ID" value="ACA88998"/>
        <property type="gene ID" value="Swoo_4749"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4749"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="CENWLRI"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="37643" checksum="C00FA863E2DE9F9A" modified="2008-04-29" version="1">MPRPRRTQMSIEDTSWYHCCSRVTRRACLFGNDELTGKNYDYRRDWVESLLLKLGDIFAIDVAAYAVMSNHLHVVLYIDIETVNRWSDRTVVEQWHQLFNGTELTQRFAKGEVIEEYQVAKLKHLVGIYRSRLCDISWFMRCLNEPIARMANKEDKCTGRFWEGRFKSQALLDEAAVLACMAYVELNPIRAQMADTLESSDHTSIQLRVNAALKGEQPTQLLPFIGDERLNQPKGINFALKDYLELVDETGRIIRNDKRGSISANSTKILTRLHISSDNWIKLTSEFGELFHGPVGNTQELTSFCEHLQKRRRHFAQCCKYLEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNG7</accession>
    <name>B1KNG7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324390.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1760"/>
    <dbReference type="EnsemblBacteria" id="ACA86044">
        <property type="protein sequence ID" value="ACA86044"/>
        <property type="gene ID" value="Swoo_1760"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1760"/>
    <dbReference type="eggNOG" id="ENOG5033139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155686_0_0_6"/>
    <dbReference type="OMA" id="CELHNRY"/>
    <dbReference type="OrthoDB" id="1917736at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018551">
        <property type="entry name" value="DUF2007"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09413">
        <property type="entry name" value="DUF2007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBP2-type" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="11885" checksum="778FA81F0AD902FE" modified="2008-04-29" version="1">MEERNRMVAGGNLLQAHTWKGLLEACGIEVQLKGEALLGGIGELPVDLQNVELWVPESQYEKAKAQLESLNTESPQWQCVQCHEMNEDSFELCWQCSAERCVQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI9</accession>
    <name>B1KNI9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FeS assembly protein IscX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324412.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1782"/>
    <dbReference type="EnsemblBacteria" id="ACA86066">
        <property type="protein sequence ID" value="ACA86066"/>
        <property type="gene ID" value="Swoo_1782"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1782"/>
    <dbReference type="eggNOG" id="COG2975">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168040_1_0_6"/>
    <dbReference type="OMA" id="AIQQAWI"/>
    <dbReference type="OrthoDB" id="1860577at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007479">
        <property type="entry name" value="ISC_FeS_clus_asmbl_IscsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036762">
        <property type="entry name" value="IscX-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37532">
        <property type="entry name" value="PTHR37532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04384">
        <property type="entry name" value="Fe-S_assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039003">
        <property type="entry name" value="IscX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140319">
        <property type="entry name" value="SSF140319"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03412">
        <property type="entry name" value="iscX_yfhJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="65" mass="7582" checksum="795C398CD7E79C8B" modified="2008-04-29" version="1">MSLKWIDSLDIAIELLEKFPEVDPVSVRFTDLYEWVLALDAFDDDPNHCNERVLEAIQACWISEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL3</accession>
    <name>B1KNL3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1806</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324436.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1806"/>
    <dbReference type="EnsemblBacteria" id="ACA86090">
        <property type="protein sequence ID" value="ACA86090"/>
        <property type="gene ID" value="Swoo_1806"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1806"/>
    <dbReference type="eggNOG" id="COG1760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022305_0_1_6"/>
    <dbReference type="OMA" id="SAAMGGC"/>
    <dbReference type="OrthoDB" id="225730at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="3"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="188"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="458" mass="49073" checksum="22A36212E3B65A75" modified="2008-04-29" version="1">MISVFDMFKIGIGPSSSHTVGPMKAGNIFIEDLQKAGLLDTTDELRSELFGSLGQTGKGHGTGKAVILGLMGEAPDTVDTDAIDGILNEVSQSEVLLMANGTKVTFTRELGITYHRRKSLPAHANAMTLYAYRQGQCIFERTYYSVGGGFILDQDEILAQDASPAAPIKSAPYDFNSATQLLTLCTDNGLSISSLMMENELSIASEAEIKQQLWIIWQTMKNCVERGYKKEGILPGGLKLRRRAPAMYRRLKAEGKNSVDPLTALDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDMFVQEVDLEVCCRYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTEIMGGTIEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAVKAINASRMALHGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNR7</accession>
    <name>B1KNR7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325861.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3255"/>
    <dbReference type="EnsemblBacteria" id="ACA87525">
        <property type="protein sequence ID" value="ACA87525"/>
        <property type="gene ID" value="Swoo_3255"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3255"/>
    <dbReference type="eggNOG" id="COG1757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018751_2_0_6"/>
    <dbReference type="OMA" id="CAMAFAT"/>
    <dbReference type="OrthoDB" id="776648at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="284"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="574" mass="62157" checksum="AF06257C6F9EAEDC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY1</accession>
    <name>B1KNY1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oligopeptidase B</fullName>
            <ecNumber evidence="3">3.4.21.83</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.83" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327329.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4763"/>
    <dbReference type="MEROPS" id="S09.010"/>
    <dbReference type="EnsemblBacteria" id="ACA89012">
        <property type="protein sequence ID" value="ACA89012"/>
        <property type="gene ID" value="Swoo_4763"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4763"/>
    <dbReference type="eggNOG" id="COG1770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011290_0_1_6"/>
    <dbReference type="OMA" id="NMGAGHG"/>
    <dbReference type="OrthoDB" id="154149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9_N" evidence="2">
        <location>
            <begin position="40"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="500"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="722" mass="82346" checksum="414301C9FA87F3FD" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP05</accession>
    <name>B1KP05_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Molybdenum transport system permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4787</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327353.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4787"/>
    <dbReference type="EnsemblBacteria" id="ACA89036">
        <property type="protein sequence ID" value="ACA89036"/>
        <property type="gene ID" value="Swoo_4787"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4787"/>
    <dbReference type="eggNOG" id="COG4149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_14_3_6"/>
    <dbReference type="OMA" id="MYSFIET"/>
    <dbReference type="OrthoDB" id="1915735at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011867">
        <property type="entry name" value="ModB_ABC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02141">
        <property type="entry name" value="modB_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="6"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA89036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="24648" checksum="604F029AAB6806C0" modified="2008-04-29" version="1">MDWQALLLSVKLSSVTVLILIPFAIFVSRFLAYRQFRGKSWVEALIMVPLVLPPTVIGYYLLVGLGSQSWLGQTLESLFGHQLVFNFSGLVIASILVNIPFAIQPIQRSFEAVPEDVCDAAACCGMSRLKVLFKIELPMVWPGVLTALVLCFSHVLGEFGVVLMMGGNIAGETKTIAISIYDSVQAFDFASAGQMSLVLLIFAVTVLAFTTSLSRRMGAGHASRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP29</accession>
    <name>B1KP29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Formate dehydrogenase, gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4811</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the formate dehydrogenase gamma subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327377.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4811"/>
    <dbReference type="EnsemblBacteria" id="ACA89060">
        <property type="protein sequence ID" value="ACA89060"/>
        <property type="gene ID" value="Swoo_4811"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4811"/>
    <dbReference type="eggNOG" id="COG2864">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047957_0_0_6"/>
    <dbReference type="OMA" id="HIYMGTI"/>
    <dbReference type="OrthoDB" id="1612137at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009326">
        <property type="term" value="C:formate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006471">
        <property type="entry name" value="Formate_DH_gsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01583">
        <property type="entry name" value="formate-DH-gamm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765094" evidence="10">
        <location>
            <begin position="32"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="11">
        <location>
            <begin position="126"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA89060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="36888" checksum="4BD2C2350BE508A7" modified="2008-04-29" version="1" precursor="true">MKLTSLRSLFASLVLPLVILMGLGLSTSALAADGQNSQQIANAKTSDADLWRAVKAGDSGYTVAQGSEAGVLINVVGNEGKNIKNEYLTPAMGVAVLGVFAAFLIFYFVNGPSKLTKGFSGKMVLRWSKADLIIHWVLAISCLGLIFTGINIMLGKHILQPYVGEGVWAALIYGSKTIHDYVGPLFIVSWILCVVKWMPLQTLKMYDLKWFLVVGGYINFGPFKGKHPDSGFANAGEKMWFWTLAIFGLFISVSGIMLVLPGLELPREASMAALLIHGLSAIIIIAFTIVHIWMATVLSEGGMECMKSGYCDENWAVQHHNLWYDEIKENGTLEYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP37</accession>
    <name>B1KP37_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfur carrier protein FdhD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fdhD</name>
        <name evidence="4" type="ordered locus">Swoo_4819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FdhD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327385.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4819"/>
    <dbReference type="EnsemblBacteria" id="ACA89068">
        <property type="protein sequence ID" value="ACA89068"/>
        <property type="gene ID" value="Swoo_4819"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4819"/>
    <dbReference type="eggNOG" id="COG1526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056887_0_0_6"/>
    <dbReference type="OMA" id="SEMVIKT"/>
    <dbReference type="OrthoDB" id="948173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097163">
        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00187">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003786">
        <property type="entry name" value="FdhD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30592">
        <property type="entry name" value="PTHR30592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02634">
        <property type="entry name" value="FdhD-NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015626">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="3">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA89068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="32736" checksum="98960048A67AD42A" modified="2008-04-29" version="1">MLLESITNCELPALSQHKPSLIKTDAEVPLTISVNAIDENGEQVEKHIACERPLTVYLNWRPIVTLMTLGARAEALALGYLKNQGFISDLEQLESVIIDWDVSSAAVLTKESTQDLEEKLSEKTVTTGCGQGTVYGGFMDGLDEITLPQPQLKQSMIYSLLKNISAYNETYKNAGAVHGCGLCQDDKIVGFVEDVGRHNAVDTLAGEMWLRQDVGHNKMFYTTGRLTSEMVIKIAKMGIPVVLSRSGATQMGLELAQKLGITMIARAKGKHFLIYNGAENIEFDAIPPKRPKKPLENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP75</accession>
    <name>B1KP75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322994.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0344"/>
    <dbReference type="EnsemblBacteria" id="ACA84645">
        <property type="protein sequence ID" value="ACA84645"/>
        <property type="gene ID" value="Swoo_0344"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0344"/>
    <dbReference type="eggNOG" id="ENOG5033AS4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180692_2_1_6"/>
    <dbReference type="OMA" id="KPPTFWQ"/>
    <dbReference type="OrthoDB" id="2084359at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021344">
        <property type="entry name" value="DUF2970"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11174">
        <property type="entry name" value="DUF2970"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="61" mass="6796" checksum="BBAE0D092A511B4A" modified="2008-04-29" version="1">MLFKAWQLFSSTLAAFLGVQSDKNRLRDFQTSSPIPFIIMGIILAAIFVITLLLIVNQVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPC9</accession>
    <name>B1KPC9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323048.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0400"/>
    <dbReference type="EnsemblBacteria" id="ACA84699">
        <property type="protein sequence ID" value="ACA84699"/>
        <property type="gene ID" value="Swoo_0400"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0400"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088255_3_0_6"/>
    <dbReference type="OMA" id="NAIHKQK"/>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001488">
        <property type="entry name" value="Tdi_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767271" description="Thiol:disulfide interchange protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="8"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="5">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001488-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="22532" checksum="9875EBB66D706419" modified="2008-04-29" version="1" precursor="true">MKKALLIALALLTAPMAALAVDYKEGVHYTVINQGPATAKPEITEFFSFYCGHCYNFSKVQVPQIKANLPEGVVFKQNHVEFIGREMGTEMSRAFAVAHQLKVEDKIEKAIFAAIHDKKQHFTNRDDVRKLFIANGVDGKAFDAAADSFMVSAQMSQMKRATENAQISGVPSLVVNGKYRVETGAIKSYDELLDIAYYLTSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPG0</accession>
    <name>B1KPG0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1829</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324459.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1829"/>
    <dbReference type="EnsemblBacteria" id="ACA86113">
        <property type="protein sequence ID" value="ACA86113"/>
        <property type="gene ID" value="Swoo_1829"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1829"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="IFAPASF"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="574"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="904"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="934"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="960"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1009"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1039"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1086" mass="118972" checksum="432D568A80798687" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS8</accession>
    <name>B1KPS8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor RpoS</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Sigma S</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sigma-38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpoS</name>
        <name evidence="8" type="ordered locus">Swoo_3342</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with the RNA polymerase core enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. RpoS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325946.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3342"/>
    <dbReference type="EnsemblBacteria" id="ACA87611">
        <property type="protein sequence ID" value="ACA87611"/>
        <property type="gene ID" value="Swoo_3342"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3342"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_5_6"/>
    <dbReference type="OMA" id="RRVQREF"/>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00959">
        <property type="entry name" value="Sigma70_RpoS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012761">
        <property type="entry name" value="RNA_pol_sigma_RpoS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02394">
        <property type="entry name" value="rpoS_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="6">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="279"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-1" evidence="5">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="86"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="5">
        <location>
            <begin position="166"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="5">
        <location>
            <begin position="254"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="322" mass="36548" checksum="12BC6BD1DA075898" modified="2008-04-29" version="1">MGRKANTAVAEPLVDLAKNESDIESTTAKTEGAELENQVQDDLQKNLDATQLYLSEIGFSPLLSAEEEVYFSRKALKGCDKSRNRMIESNLRLVVKIARRYNNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHVVKELNVYLRTARELAHKLDHEPTAEEIAEKLDLPSADVSRMLKLNERITSVDTPLGGDNDKALLDVLADDDNVGPDYKVQDEDMSKSVVKWLDELNTKQREVLARRFGLLGYEPSTLENVGKEIGLTRERVRQIQVEALKRLKDLLSAQGLSVEAIFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ30</accession>
    <name>B1KQ30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4894</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327460.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4894"/>
    <dbReference type="EnsemblBacteria" id="ACA89143">
        <property type="protein sequence ID" value="ACA89143"/>
        <property type="gene ID" value="Swoo_4894"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4894"/>
    <dbReference type="eggNOG" id="COG4773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_9_4_6"/>
    <dbReference type="OMA" id="DDRNDYF"/>
    <dbReference type="OrthoDB" id="169533at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764743" evidence="7">
        <location>
            <begin position="34"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="74"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="282"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA89143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="714" mass="80071" checksum="AD81BBD8FB6985B9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ55</accession>
    <name>B1KQ55_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4919</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327484.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4919"/>
    <dbReference type="REBASE" id="17475">
        <property type="entry name" value="M.SwoAORF4919P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89168">
        <property type="protein sequence ID" value="ACA89168"/>
        <property type="gene ID" value="Swoo_4919"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4919"/>
    <dbReference type="eggNOG" id="COG0270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006958_0_1_6"/>
    <dbReference type="OMA" id="AGYRKGF"/>
    <dbReference type="OrthoDB" id="1178320at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA89168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="416" mass="46796" checksum="16DBEF5E0344116C" modified="2008-04-29" version="1">MKTDPNSLEQAKILIEPMVLPHVPEGTEPKALVDQWLHALATESEFFCDHIKSDPKQLKTEVKLLLSEAAIFINKEQFFELVFDHQKLKPVIDSKFKFIDLFAGIGGVRLGFQQNDGACVFSSEFDKHAQATYQTNHGELPFGDITAINPTHIPDHDVLLAGFPCQPFSHAGLKLGIEDTRGTLFHNIARIIEEKQPKFALLENVKGLVSHDKGYTLKVILKTLTDIGYSCNISKELIEHGTAKQIQIEAKKMVMRSVDFGVPQNRQRIYIILWKDGLIEQFQYPKPSGKDTKVADILESEPCEKLTISDKLWAGHKRRKIENKAKGKGFGYGLVSPESEYTNTISARYYKDGSEILLDQEGRNPRKISPREAARLQGFPEEFAFSASKTQAYKQFGNSVSVPVIDALAKEIKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ61</accession>
    <name>B1KQ61_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327490.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4925"/>
    <dbReference type="EnsemblBacteria" id="ACA89174">
        <property type="protein sequence ID" value="ACA89174"/>
        <property type="gene ID" value="Swoo_4925"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4925"/>
    <dbReference type="HOGENOM" id="CLU_2669037_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="75" mass="8621" checksum="3AA572134CAEF63E" modified="2008-04-29" version="1">MALPKGVNAAASFQNKMSFYSIKAIYHREQGEKPSRRDISGSTKRCRCGYDLPKQDEVLRSETLRMRDRDIELAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA3</accession>
    <name>B1KQA3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:neurotransmitter symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0460"/>
    <dbReference type="EnsemblBacteria" id="ACA84758">
        <property type="protein sequence ID" value="ACA84758"/>
        <property type="gene ID" value="Swoo_0460"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0460"/>
    <dbReference type="eggNOG" id="COG0733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006855_3_0_6"/>
    <dbReference type="OMA" id="AQHNGVQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="436" mass="47522" checksum="E875DAED6E9E126F" modified="2008-04-29" version="1">MAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLVLILILGYPMLVAELMIGRHGQTNPADAMAKIGSGPVSKKIGKAIGFISIATATLICTFYTILSGWFVSFALAPIAELFGFVKVSSWLMEFSLSRNLVFTTLFILMVVFVIRQGVQQGIELWSKRLMPLLLLILVMGVIYILTQTGAMTGLEVLLVPDFSRVWEPDVLIGALGQTFFSLTIGTGAMMVYGAYLSRKEDLGKLTAYVTLTDTSVAFLAALMIIPAMYVAQHNGVQIFAEDGSLLNSDTLVFTVLPALFETLGGNLQYLLAFVFFILMTIAGLTSAISIVEVPTSYLMEKKSISRNKATYLIGALVVVLSLTVVLNFEQLFSFMITLTTERAQPLIALGIAIYLGWVWQRNDLLKDIQAQEGADSNSIFWRIWPVYVKFVCPALITLIIIQLFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD5</accession>
    <name>B1KQD5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hemerythrin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323139.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0492"/>
    <dbReference type="EnsemblBacteria" id="ACA84790">
        <property type="protein sequence ID" value="ACA84790"/>
        <property type="gene ID" value="Swoo_0492"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0492"/>
    <dbReference type="eggNOG" id="COG2846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076075_0_1_6"/>
    <dbReference type="OMA" id="ACTTWRV"/>
    <dbReference type="OrthoDB" id="1701106at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019903">
        <property type="entry name" value="RIC_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36438">
        <property type="entry name" value="PTHR36438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04405">
        <property type="entry name" value="ScdA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03652">
        <property type="entry name" value="FeS_repair_RIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="4">
        <location>
            <begin position="88"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="26676" checksum="1CCE0A2E781FB675" modified="2008-04-29" version="1">MSLTTQSDVSLSEQGVGQLVAKDFRYAHIFSQFGIDFCCGGGRSLANACNKANIELSDVMSELKKLERTGQKEDALNQLPVAELIDYIEAKHHSYVREKSPLLVEYSQKMVRAHGEHYAEIKPLAGWIRALVDDLTPHLMKEEQILFPAIRAMGSGETVNACFGHIGNPINAMQHEHDDAARILEKLHELTNDFQPPEHACTTWRVCYATLAEFEADLKQHIHLENNILFPKALALAN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQN1</accession>
    <name>RSMF_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase F</fullName>
            <ecNumber evidence="1">2.1.1.178</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA m5C1407 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (cytosine-C(5)-)-methyltransferase RsmF</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmF</name>
        <name type="ordered locus">Swoo_1986</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(1407) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1407) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42756"/>
            <dbReference type="Rhea" id="RHEA-COMP:10223"/>
            <dbReference type="Rhea" id="RHEA-COMP:10224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.178"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.178" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324616.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQN1"/>
    <dbReference type="SMR" id="B1KQN1"/>
    <dbReference type="STRING" id="392500.Swoo_1986"/>
    <dbReference type="EnsemblBacteria" id="ACA86270">
        <property type="protein sequence ID" value="ACA86270"/>
        <property type="gene ID" value="Swoo_1986"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1986"/>
    <dbReference type="eggNOG" id="COG0144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_6_2_6"/>
    <dbReference type="OMA" id="PWCAEGF"/>
    <dbReference type="OrthoDB" id="1064993at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016434">
        <property type="term" value="F:rRNA (cytosine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01579">
        <property type="entry name" value="16SrRNA_methyltr_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="Fmu/NOL1/Nop2p_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031341">
        <property type="entry name" value="Methyltr_RsmF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027391">
        <property type="entry name" value="Nol1_Nop2_Fmu_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023545">
        <property type="entry name" value="rRNA_ssu_MeTfrase_F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17125">
        <property type="entry name" value="Methyltr_RsmF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13636">
        <property type="entry name" value="Methyltranf_PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000185646" description="Ribosomal RNA small subunit methyltransferase F">
        <location>
            <begin position="1"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="121"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01579"/>
        </source>
    </evidence>
    <sequence length="478" mass="53653" checksum="D695AF254D0D1D5A" modified="2008-04-29" version="1">MVQLNQDFINSIAKDMPAHLTMDDFISYSSKPLRPSIRINTLKISSDEFVTLMAAKGWTLDPIPWCSDGFWVALDNEIQLGNTIEHIQGLFYIQEASSMLPPTALFDGLDNSSEYTILDMASAPGSKTTQMASLMDNKGLLVANEYSSSRVKVLHANVQRMGVYNTALTHFDARVFGEYLYHQFDAILLDAPCSGEGTIRKDPLALRNWSLEENASIIETQKALIESAFLALKTGGSLVYSTCALSRSENQEVCEHLMSCFPQAVEFQSLSELFPDADKSCTSEGFLHVWPQIYDSEGFFIAKVRKVADVERQKPLPKAQRNFPFTAANNKTKDELSHYFKHTFGISLPKDGLIMERDLEYWLFPAKMADFIGKMRFQRIGLKLADGLKKGFKVRHEAIMALSDKHNAIELNESQAIEYLMGRDIPLQDGGKPQGEVILTYHHCALGVAKHLGKRLKNNLPRELVRDKVISAKAKTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR3</accession>
    <name>B1KQR3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Na(+)-translocating NADH-quinone reductase subunit E</fullName>
            <shortName evidence="10">Na(+)-NQR subunit E</shortName>
            <shortName evidence="10">Na(+)-translocating NQR subunit E</shortName>
            <ecNumber evidence="10">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NQR complex subunit E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">NQR-1 subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nqrE</name>
        <name evidence="11" type="ordered locus">Swoo_3401</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326004.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3401"/>
    <dbReference type="EnsemblBacteria" id="ACA87669">
        <property type="protein sequence ID" value="ACA87669"/>
        <property type="gene ID" value="Swoo_3401"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3401"/>
    <dbReference type="eggNOG" id="COG2209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095255_0_0_6"/>
    <dbReference type="OMA" id="MGMCTFL"/>
    <dbReference type="OrthoDB" id="1814639at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00429">
        <property type="entry name" value="NqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010967">
        <property type="entry name" value="NqrE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30335:SF1">
        <property type="entry name" value="PTHR30335:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01940">
        <property type="entry name" value="nqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="8 10 11" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="202" mass="21759" checksum="0A3709B5B0416D4B" modified="2008-04-29" version="1">MEHYINLFIQAAFIDNMALSFFMGMCTFLAVSKKVSTSFGLGIAVIVVMTIAVPINQVIYANVLAPGALAWAGYPELNLSYLQLITFIGVIAALVQILEMFLDKYIPSLYDSLGIFLPLLTVNCAIFAGVIFMANRDYSLGESAVFAMGSGVGWAMAIVMLAGLRERMKFHAIPEGLQGIGIVFITTGLMALGFMAFSGISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT9</accession>
    <name>B1KQT9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-acetylhomoserine/O-acetylserine sulfhydrylase</fullName>
            <ecNumber evidence="5">2.5.1.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326030.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3427"/>
    <dbReference type="EnsemblBacteria" id="ACA87695">
        <property type="protein sequence ID" value="ACA87695"/>
        <property type="gene ID" value="Swoo_3427"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3427"/>
    <dbReference type="eggNOG" id="COG2873">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_4_2_6"/>
    <dbReference type="OMA" id="TYTLFAH"/>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="429" mass="46068" checksum="458BCB7A5D3EDD91" modified="2008-04-29" version="1">MKLESLALHHGYESEATTKAAAVPIYQTTSYTFDDTQHGADLFDLKVPGNIYTRIMNPTTDVLEQRLAAIEGGIGALAVASGMAAITYAIQALTQVGDNIVSTSQLYGGTYNLFAHTLPRQGVDVRMAAFDDFDGLEALIDENTKALFCESIGNPAGNIVDIERLANIAHKHGIPLMVDNTVATPVLCKPFEYGADIVIHSLTKYIGGHGTTIGGVIIDSGKFDWAAQPKRFALLNEPDASYHGVVYTQAFGPAAFIGRCRVVPLRNTGAALAPQSAFLLLQGLETLSLRMERHCSNALTLAEYLEKHPKVSWVNYAALPNSPFQDNCHKITNGKASGIISFGIKSTLAGGGKEAGGHFIDGLKMILRLVNIGDAKSLACHPASTTHRQLDAEELAKAGVSEDLVRISVGIEHIDDIIFDVEQALEQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQW1</accession>
    <name>B1KQW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microbial collagenase</fullName>
            <ecNumber evidence="2">3.4.24.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.24.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326052.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3449"/>
    <dbReference type="EnsemblBacteria" id="ACA87717">
        <property type="protein sequence ID" value="ACA87717"/>
        <property type="gene ID" value="Swoo_3449"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3449"/>
    <dbReference type="eggNOG" id="COG1512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914965_0_0_6"/>
    <dbReference type="OMA" id="PSDNGGM"/>
    <dbReference type="OrthoDB" id="43759at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002169">
        <property type="entry name" value="Peptidase_M9A/M9B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01752">
        <property type="entry name" value="Peptidase_M9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00931">
        <property type="entry name" value="MICOLLPTASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764764" evidence="1">
        <location>
            <begin position="23"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="33071" checksum="F0913649ECE7C309" modified="2008-04-29" version="1" precursor="true">MKVSNLLPIATLLSLYTFTANAESSSLSEILTQEHACSDTILIRSQALSQAQIAQACQLLSTQEAKFHALFGTRGKPVANDNNVSMRANVYHSREDYVQYVTAHFDVPSDNGGMFLEGLPHKLNNQAEFVAYEKKGQIWNLAHEYVHYLDGHFNLYGDFCASLHDSHSAPEYCPKPAPLLPHLVWWSEGLGEYISQGDNNEAAIKLAKDSLASETSYPLSELFNTSYEINGGSDRVYRWGYLAVRFMIEQHRDKIEQMLTFTRKGDYPRYQALVKQWGAQMDGEFKDWLISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ6</accession>
    <name>B1KQZ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MbcT/ParT/Res family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3486"/>
    <dbReference type="EnsemblBacteria" id="ACA87752">
        <property type="protein sequence ID" value="ACA87752"/>
        <property type="gene ID" value="Swoo_3486"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3486"/>
    <dbReference type="eggNOG" id="COG5654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074555_1_0_6"/>
    <dbReference type="OMA" id="MAPFTHV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014914">
        <property type="entry name" value="RES_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08808">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00953">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RES" evidence="2">
        <location>
            <begin position="75"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25524" checksum="368C92FF4DE5514F" modified="2008-04-29" version="1">MSSTLTSEKAYRLVNTRFPAIDIFDDCASVEEFEVLFALQSLTNPRLQNEVGDLTLLSNDQIPFGITGCSYATASFTHINRDGSRFSNGEFGVLYMADTMKTAIAETRYHVQKMLSLIEGLHFEMIVMKGLSCTISGELIDIRANTIAQMQTTDIYHHTDYTASQHLGFKYRKQAVEGLHYTSVRNPMSSCYALFTPKRVEEIIQSTHYEYVWDGKSIEVRGITAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR62</accession>
    <name>B1KR62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323227.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0583"/>
    <dbReference type="EnsemblBacteria" id="ACA84879">
        <property type="protein sequence ID" value="ACA84879"/>
        <property type="gene ID" value="Swoo_0583"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0583"/>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2636077_0_0_6"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="77" mass="8864" checksum="EAA100BB0AB05976" modified="2008-04-29" version="1">MPLKKFLLGNTLATGLWLGLFGLGPLFIRNELTPILSFYHHHQHLFWLVTTSLIIITLVALSTVMKRRRDQTDTDCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRA1</accession>
    <name>B1KRA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA alkylation repair enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2024"/>
    <dbReference type="EnsemblBacteria" id="ACA86308">
        <property type="protein sequence ID" value="ACA86308"/>
        <property type="gene ID" value="Swoo_2024"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2024"/>
    <dbReference type="eggNOG" id="COG4912">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079880_2_0_6"/>
    <dbReference type="OMA" id="GYGWMLK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="29872" checksum="C0F6ECEDB5BE77E8" modified="2008-04-29" version="1">MDICMDSYRDFHQYLKQELQAVSSEEKAASMRRYFPNGLVCIGAISEDINQISAEFIREHDAMLPEGYLSLAEYILERAEFHEEILISYRLIEKLVKRHFDDNLLVRFQYWLENYANNWALVDDLCIKAIYNYLYARPHLIEKTQLWARSEVSWCRRASNVVWVKFIYRKMGKQVYRLNPELVFSNCDLHIHDPDEFVQKSVGWLLKVTTPHHHDAVVNYIKTNIASMQKSTVRYALEKVPKETRDEIMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH3</accession>
    <name>B1KRH3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione synthase</fullName>
            <ecNumber evidence="4">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_2096</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2096"/>
    <dbReference type="EnsemblBacteria" id="ACA86380">
        <property type="protein sequence ID" value="ACA86380"/>
        <property type="gene ID" value="Swoo_2096"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2096"/>
    <dbReference type="eggNOG" id="ENOG502Z9VE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025152_3_0_6"/>
    <dbReference type="OMA" id="NGLVMYP"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="PTHR11130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSH_synthase" evidence="11">
        <location>
            <begin position="206"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="486" mass="54703" checksum="A6799E967074996E" modified="2008-04-29" version="1">MSSADKPLIDKQVIEEACEWSIMHGVAFKNSDGTARHCPFSIAPMTMKHNVFQHIMKVTPLLTKLISRVSEDHLFLQSSLTEMAKADQFFERLMAIHKEIHGVDGEQTFPARQPLLLMRTDYMDDRQQGAKVIEFNGIAAGMGPFGQRITQLHQFMKNQWPEVYTDWVEDPASYVADNFCLEQLAEGIAHGAHKVKAEFDVSGQPTFLMVVQRGEDNVYDQHLLEVALQGLGVRTLRRTFDQLASELYTGENKRLMLKGIGAIDLVYLRAGYQHIDYFAPALGEDICCQTLSQTRAFIEQHNVALNATISQQLATSKTMQMILTMMPEQEFSRWGFTLEEVRLIKSVLAEMLPVNKETIDWFSSRADKTAWVLKNQGEGGGHCVFGEEITERLSQLKPEEYGAWALMQRLFPHERERPTLAVRDGEITKIDDLISEIGLFTAYFNGKPVAGSEGLVGYLVRSKPAKENEGGIHSGQGILDSITLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCW2</accession>
    <name>B1KCW2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">16S rRNA (cytosine(967)-C(5))-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">16S rRNA m5C967 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">rRNA (cytosine-C(5)-)-methyltransferase RsmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_0036</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(967) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(967) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42748"/>
            <dbReference type="Rhea" id="RHEA-COMP:10219"/>
            <dbReference type="Rhea" id="RHEA-COMP:10220"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.176"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.176" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322686.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0036"/>
    <dbReference type="EnsemblBacteria" id="ACA84337">
        <property type="protein sequence ID" value="ACA84337"/>
        <property type="gene ID" value="Swoo_0036"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0036"/>
    <dbReference type="eggNOG" id="COG0144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_0_4_6"/>
    <dbReference type="OMA" id="RVNRQHH"/>
    <dbReference type="OrthoDB" id="1064993at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="Fmu/NOL1/Nop2p_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004573">
        <property type="entry name" value="rRNA_ssu_MeTfrase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00563">
        <property type="entry name" value="rsmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="13">
        <location>
            <begin position="159"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="12">
        <location>
            <begin position="248"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA84337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="425" mass="47304" checksum="1471EC04E8C6503A" modified="2008-04-29" version="1">MNLRALAAKVVFQVLEKGISLSVALPEQQKHCESGKDKALLAELSYGVMRQLPQLDKLISDCMAKPLKGKQRILHQLLLVGCYQLYFTRIPSHAAISETAEACRQLKFDGLVKVINAVLRNIQRQEKPLPTDNDTLTYNTPAWIIKSLKQAYPDSWQTVIENSHQRPPMWLRNNVRSQTRDEYLALLAEAEISASAGQSSDAILLESPKDVMQLPGFEQGAASVQDGAAQWAATLLAPADGELILDACAAPGGKTCHILERADTELVAVDFDANRLERVQQNLDRLSLNAKLVHGDAADIDSWWQGDKFDRILLDAPCSATGVIRRHPDIKWLRKQADIEELAQLQSKILDHCWKWLKPGGTLLYATCSILPQENAQQISAFLERTHDATLIAISQQPNPDDIGWQITPGTENMDGFYYARLVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ7</accession>
    <name>B1KCZ7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [quinone]</fullName>
            <ecNumber evidence="5">1.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [menaquinone]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [ubiquinone]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen oxidase</fullName>
            <shortName evidence="5">PPO</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hemG</name>
        <name evidence="7" type="ordered locus">Swoo_0025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a menaquinone + protoporphyrinogen IX = 3 a menaquinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:27409"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.5.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a quinone + protoporphyrinogen IX = 3 a quinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:65032"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a ubiquinone + protoporphyrinogen IX = 3 a ubiquinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:63936"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5">Binds 1 FMN non-covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HemG family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322675.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0025"/>
    <dbReference type="EnsemblBacteria" id="ACA84326">
        <property type="protein sequence ID" value="ACA84326"/>
        <property type="gene ID" value="Swoo_0025"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0025"/>
    <dbReference type="eggNOG" id="COG4635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094839_0_1_6"/>
    <dbReference type="OMA" id="IEYTDWE"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070819">
        <property type="term" value="F:menaquinone-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00853">
        <property type="entry name" value="HemG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044264">
        <property type="entry name" value="HemG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 5" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_5" evidence="6">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="20092" checksum="1972656DF8790234" modified="2008-04-29" version="1">MNKTLIIYSTVDGQTRAICELMKGVNQAAESEVTLASLEEAKALSLADFDKVMIGASIRYGKHRPELYQYINNHHAVLSAKPNAFFTVNVVARKPEKNTPETNPYMKKFLELSLWKPQQLGVFAGKIDYPKYRFFDKTMIRFIMWMTKGPTDTSGTYEFTNWQQVEEFGKAFADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD02</accession>
    <name>B1KD02_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322698.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0048"/>
    <dbReference type="EnsemblBacteria" id="ACA84349">
        <property type="protein sequence ID" value="ACA84349"/>
        <property type="gene ID" value="Swoo_0048"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0048"/>
    <dbReference type="eggNOG" id="ENOG50331AY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190004_0_0_6"/>
    <dbReference type="OMA" id="MNQSIQF"/>
    <dbReference type="OrthoDB" id="1924250at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009962">
        <property type="entry name" value="DUF1488"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036692">
        <property type="entry name" value="Shew3726-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07369">
        <property type="entry name" value="DUF1488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160272">
        <property type="entry name" value="SSF160272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="87" mass="10238" checksum="8631F1B43157EDA4" modified="2008-04-29" version="1">MNQSILFPDLQEWNEELQEIHFPAQVQGANIECRISLARLVKLEGKEVQSQQEALKVFDAYRFDIEDEVEMLIEQEEFDEQGRVVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD16</accession>
    <name>B1KD16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3587"/>
    <dbReference type="EnsemblBacteria" id="ACA87851">
        <property type="protein sequence ID" value="ACA87851"/>
        <property type="gene ID" value="Swoo_3587"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3587"/>
    <dbReference type="eggNOG" id="ENOG5031AQ2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2994224_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="57" mass="6335" checksum="9F626824A0528CA3" modified="2008-04-29" version="1">MSKIELQVNFNSKRLTTGVNAAVTFDIKDDVAERIGTYLQRVAEVFALKPAASNKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD55</accession>
    <name>B1KD55_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326223.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87890">
        <property type="protein sequence ID" value="ACA87890"/>
        <property type="gene ID" value="Swoo_3626"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3626"/>
    <dbReference type="HOGENOM" id="CLU_2119458_0_0_6"/>
    <dbReference type="OrthoDB" id="2085880at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="13156" checksum="8E2DC6B10ADB1FAB" modified="2008-04-29" version="1">MLVITIVILVTVTYLYVFRDQEIRLEFIPPELEFCGKKISKGDQEYDELLKVLTAHKGGWNASFTSFVPTQVYFSPAFKVNIVGKQVVVSYKTDEGYPQFIKLIKYNWFSSCAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDK8</accession>
    <name>B1KDK8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2121</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324750.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2121"/>
    <dbReference type="EnsemblBacteria" id="ACA86405">
        <property type="protein sequence ID" value="ACA86405"/>
        <property type="gene ID" value="Swoo_2121"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2121"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_382958_0_0_6"/>
    <dbReference type="OMA" id="SPIWIDD"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022510">
        <property type="entry name" value="Sortase_His-kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03785">
        <property type="entry name" value="marine_sort_HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="442"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="505"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="725" mass="81323" checksum="953E2D09621AD74C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDN6</accession>
    <name>B1KDN6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endopeptidase La</fullName>
            <ecNumber evidence="1">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324778.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2149"/>
    <dbReference type="MEROPS" id="S16.A10"/>
    <dbReference type="EnsemblBacteria" id="ACA86433">
        <property type="protein sequence ID" value="ACA86433"/>
        <property type="gene ID" value="Swoo_2149"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2149"/>
    <dbReference type="eggNOG" id="COG1067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014785_2_0_6"/>
    <dbReference type="OMA" id="HYLFICA"/>
    <dbReference type="OrthoDB" id="128102at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041699">
        <property type="entry name" value="AAA_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13654">
        <property type="entry name" value="AAA_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="2">
        <location>
            <begin position="299"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="543" mass="60549" checksum="33BBDF204D2254DE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ5</accession>
    <name>B1KDQ5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative beta-barrel assembly-enhancing protease</fullName>
            <ecNumber evidence="8">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2169</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M48 family. BepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324796.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2169"/>
    <dbReference type="MEROPS" id="M48.023"/>
    <dbReference type="EnsemblBacteria" id="ACA86452">
        <property type="protein sequence ID" value="ACA86452"/>
        <property type="gene ID" value="Swoo_2169"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2169"/>
    <dbReference type="eggNOG" id="COG4783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030556_1_1_6"/>
    <dbReference type="OMA" id="HLSQRHF"/>
    <dbReference type="OrthoDB" id="1445800at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00997">
        <property type="entry name" value="Protease_BepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030873">
        <property type="entry name" value="Protease_BepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 8" id="KW-0574">Periplasm</keyword>
    <keyword evidence="1 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009007460" description="Putative beta-barrel assembly-enhancing protease" evidence="8">
        <location>
            <begin position="29"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="9">
        <location>
            <begin position="73"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="486" mass="54044" checksum="077F221EE7569112" modified="2008-04-29" version="1" precursor="true">MSKFTSTKSLLAGALSLIFCATAPLSFANNDLPDLGTAAVNTFSLEKETVFGDAYMRVIRSSAPMLNDPVLSQYLTELGNKLVAHATGVKTPFYFFLLRNDEINAFAFFGGHVGVHTGLFLNADNESQIASVLGHEITHVTQRHLARSLEAQNKSSTATMVGMLGAILLTIAAPQAGMAALATTQALSTQAKINYTRLHEKEADRIGMQILVDAGFDPNGASDFFAKLATRYRFTSKPPQMLLTHPLPESRITDARNRAAQYPHRYVPDNIDFQLAKARIQVRFSSYSDEAALSLFETQLAKKTYAFKNAALYGKALALFKTERFKESETIIDSLLKEDKNNLFYLDTKTDLLLQREANSEAIALLETQKRLKPTSQVININLANAYIESNQAEKAIPLLEDQIFLDKQNQLPFFLLSDAYKKTGNQAMEHFVKAESMALGADYKGAVDQLNFAYRLTEDNPLQLARIEARIRQFKQSEKALDELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX9</accession>
    <name>B1KDX9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Purine nucleoside phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3721</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3721"/>
    <dbReference type="EnsemblBacteria" id="ACA87981">
        <property type="protein sequence ID" value="ACA87981"/>
        <property type="gene ID" value="Swoo_3721"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3721"/>
    <dbReference type="eggNOG" id="COG1496">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065784_1_1_6"/>
    <dbReference type="OMA" id="CFADCVP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00726">
        <property type="entry name" value="TIGR00726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="28300" checksum="815C0DFB1AC7673C" modified="2008-04-29" version="1">MIDKNVMKDRGWHIPANVNIAFTTRQNGVSRAPYASLNLGLHVGDVSEDVLANRALVQERLQLPVSPAWLNQIHSTHVVNADNRSVQDADGSYSSSRSQVCVVMTADCLPVLLCDKSGTQVAAVHAGWKGLCKGIIEAALEKFDCPNDELIAYLGPAIGPLQFEVGAEVRALFLSQHKEADPFFIKKTTTTPARQTEHHSEDKYLADLQGLAKLRLTLAGVSDIYQSDICTFNHPDYFSYRKEQITGRMASYIWLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE62</accession>
    <name>B1KE62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323395.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0753"/>
    <dbReference type="EnsemblBacteria" id="ACA85048">
        <property type="protein sequence ID" value="ACA85048"/>
        <property type="gene ID" value="Swoo_0753"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0753"/>
    <dbReference type="eggNOG" id="ENOG5033AQK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1049513_0_0_6"/>
    <dbReference type="OMA" id="WERTVWK"/>
    <dbReference type="OrthoDB" id="1888743at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="291" mass="32716" checksum="793837273BB8DDF5" modified="2008-04-29" version="1">MNRFNTKQRGQAMVESVVGLSYVIVPLLILLPFMSKLTGIQHRAEQASHYSAWERTVWKNRQPSQLPRRSGIYLARKSEADLARQIPWRFYQQDGNQIASSTNEQWDWSEHVHPLVEHQVQQGAAQDLQPLVKSNQDNPNNSDELDRFTRSSNGSRLPGVLNGATSTALGVISFMGFSLERDQFYRTNVSTQVENFYIEPFDELDLNFNSQSALLASGWNAAGPYHVKNRTRKLVLTNVMDNGVIRTAQRLMGILPFGKDLRPSSLKLGHVSPDVLPANRLCTYGTANCGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEG0</accession>
    <name>B1KEG0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c550</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2257</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2257"/>
    <dbReference type="EnsemblBacteria" id="ACA86538">
        <property type="protein sequence ID" value="ACA86538"/>
        <property type="gene ID" value="Swoo_2257"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2257"/>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084762_1_0_6"/>
    <dbReference type="OMA" id="HGNVTPQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030991">
        <property type="entry name" value="c550_PedF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04494">
        <property type="entry name" value="c550_PedF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="76"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="18057" checksum="F62CEC971BB5AD26" modified="2008-04-29" version="1" precursor="true">MHEIRNYDDKGGFEMKIVSVKRKFLLASIFIVGAFNVSAHGPVTPQSIDTTSLPQLGEEWLEENPYRDQNSDKQSDILRIGASAYNQNCARCHGLEGISGGIAPDLRQLAPDLDGDEWYGYRVQNGAVRNGAVYMPKMTEHLTQEALWAIRTWLESVSEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET2</accession>
    <name>B1KET2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SapC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326427.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3838"/>
    <dbReference type="EnsemblBacteria" id="ACA88097">
        <property type="protein sequence ID" value="ACA88097"/>
        <property type="gene ID" value="Swoo_3838"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3838"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074824_0_0_6"/>
    <dbReference type="OMA" id="GEWDAVY"/>
    <dbReference type="OrthoDB" id="1512520at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010836">
        <property type="entry name" value="SapC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07277">
        <property type="entry name" value="SapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="242" mass="27662" checksum="9780F84B520BA119" modified="2008-04-29" version="1">MSNLVQLTACEHQSLHLDPHKCGQHGSKLNMIPVVLSEFRQLITQYPIVLTKNGDTGAFTFVALLGFGEGENLFWHDDEWRSIYLPLQIRRQPFFVGPKESQTGEHPLCIDIDSPTLSKEPKGIPLYGKQGEESEHLQEAKQHLAQLLRGEADNQAFLQLLQELKLLQPLSVEIAFEHANPTRLNGLYTIDEKQFNNLSDAQLLRLHRTQFFEPIYMMIASLGQIYSLIEMKNRRDSPDQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET3</accession>
    <name>B1KET3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326428.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3839"/>
    <dbReference type="EnsemblBacteria" id="ACA88098">
        <property type="protein sequence ID" value="ACA88098"/>
        <property type="gene ID" value="Swoo_3839"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3839"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100937_0_0_6"/>
    <dbReference type="OMA" id="FYPGKRK"/>
    <dbReference type="OrthoDB" id="1030262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045617">
        <property type="entry name" value="DUF6445"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20043">
        <property type="entry name" value="DUF6445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="243" mass="27351" checksum="550AE857EED09210" modified="2008-04-29" version="1">MAADLLSDRSVIFNPDAKPVLHTVGEERTPLLIIDDLLLNPDAMVKQACRPPEFSTNNQDFYPGKRKAAPLDYDEQLIQRYSALIRSSYGIGQSKQPNTLLSAFSLTMTKAKALRPIQMLPHFDSPSSDQFAVVHYLFSAPLGGTSLYRHRESRFESITHERLPLYGKRLKQQAYGMQLHQNPAYTNGSSPLFEQVHSVDPKFNRAIIYPSNCLHSADIRADSKLTDNPATGRLTLNSFILFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET8</accession>
    <name>B1KET8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326433.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3845"/>
    <dbReference type="EnsemblBacteria" id="ACA88103">
        <property type="protein sequence ID" value="ACA88103"/>
        <property type="gene ID" value="Swoo_3845"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3845"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_4_6"/>
    <dbReference type="OMA" id="RRYWEDT"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="197" mass="22123" checksum="BAA266A58540DE62" modified="2008-04-29" version="1">MLYSLIKKQGITRADMTISTVDKIIDIAESQVRAGGYNSFSFREISKEIGIKSASIHYHFPTKADLGVAIANRYTARFEEHLANIIASTTEPLERLDPYIALFSHALKVDKKMCLCGVLASESDVLPEELQLEAKHFFDVNIEWLATALFPEHPQAKAHANFIIASLEGGLLMSKVMKSNRHFELITDGLRAQNWPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF04</accession>
    <name>B1KF04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family with acetyltransferase activity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0861"/>
    <dbReference type="EnsemblBacteria" id="ACA85155">
        <property type="protein sequence ID" value="ACA85155"/>
        <property type="gene ID" value="Swoo_0861"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0861"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065219_2_0_6"/>
    <dbReference type="OMA" id="NEHIYDS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="35"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="176"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="334" mass="36759" checksum="81BB151A8A29ADD2" modified="2008-04-29" version="1">MLVASKTLTEGIRLTSFSNSVTDLDSEPCPRVRARAGLRAVSRHIVRQLGMLNSAFGELPLSPVQAHALIELSNEAVSIKQLAQRLNIDKSNASRAVTHLTEKGFAYTQCNPKDTRSLLAHLTPQGKKLLQKLHQQQNTMFDQILSQLSTEEATTIESAMATYNKAISRTQAQQGYTIREVTHEDDLAIAKLIREVSAEYGLSADKGFSVADPSLDNTSEQYQATGACYWVIELDGELLGGVGIAPLSGEKGVCELQKMYFSKQLRGKGFAKRMAYLALDYACEQKYQTCYLETTACLTEAISLYESLGFEHISQHLGDTGHDACEMPMLLALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF85</accession>
    <name>B1KF85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2347</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324968.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2347"/>
    <dbReference type="EnsemblBacteria" id="ACA86626">
        <property type="protein sequence ID" value="ACA86626"/>
        <property type="gene ID" value="Swoo_2347"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2347"/>
    <dbReference type="eggNOG" id="ENOG5033A1K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_976103_0_0_6"/>
    <dbReference type="OMA" id="INRACAL"/>
    <dbReference type="OrthoDB" id="1511030at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="38"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="164"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="32521" checksum="CB9AA63C5FDB19EA" modified="2008-04-29" version="1" precursor="true">MTLFFISIVLIAALGYLAQSIGLCMVRGVNQAADGKPMFLLAILFSGVLSWISILVGYYFDIQTPFISYEFSLWALFGGFLFGFGAAVNNGCGVSTISRLARGHLAMLLTVGGWLAGWVLLTKLAPNINLVIFNLSPIWHNSMLALLSVMILFLLFSMSSYNRKVWVSMLLIGLMASIVFLTEQHWTPSALLKDISQSVWSEGKGLWPTTERFILIAALVTGMLVAALKARTFQLLPVNCSQCIKHLSAGVLMGVGAAIASGGNDTQLLLALPSFSPAGVSTVFSMLVGIYLGRKLVVLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF88</accession>
    <name>B1KF88_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324971.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2350"/>
    <dbReference type="EnsemblBacteria" id="ACA86629">
        <property type="protein sequence ID" value="ACA86629"/>
        <property type="gene ID" value="Swoo_2350"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2350"/>
    <dbReference type="HOGENOM" id="CLU_2083261_0_0_6"/>
    <dbReference type="OrthoDB" id="2014301at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="117" mass="13122" checksum="6C5C9EC43A4F1005" modified="2008-04-29" version="1">MATLTRQSVQQCIMASYGQYCISAQGDIVCNTADDGNVTIQCQIVNTRFNSGFAGDRMRVDEVDDLRVWCQTHPGLENGVNWSFGFRGTDHAHPDSINVTLIDRTNLMFNFHIYLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFB5</accession>
    <name>B1KFB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Blue (Type 1) copper domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324998.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2377"/>
    <dbReference type="EnsemblBacteria" id="ACA86656">
        <property type="protein sequence ID" value="ACA86656"/>
        <property type="gene ID" value="Swoo_2377"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2377"/>
    <dbReference type="eggNOG" id="COG3794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084115_3_0_6"/>
    <dbReference type="OMA" id="ICAIHPR"/>
    <dbReference type="OrthoDB" id="1654242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766528" evidence="1">
        <location>
            <begin position="21"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="12499" checksum="93E1894E9E5B6503" modified="2008-04-29" version="1" precursor="true">MRRITLPILLLSMTSHISLAEEYVVSQKNKSFSEDKISINVGDTVHFLNEDPFFHNIFSLSDEQFFDLGSYPKDESRSVVFDTPGVIEVECAIHSKMFLLIEVKKSENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC7</accession>
    <name>B1KFC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2389</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325010.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2389"/>
    <dbReference type="EnsemblBacteria" id="ACA86668">
        <property type="protein sequence ID" value="ACA86668"/>
        <property type="gene ID" value="Swoo_2389"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2389"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_3_3_6"/>
    <dbReference type="OMA" id="IDCDPQP"/>
    <dbReference type="OrthoDB" id="1087129at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DAO" evidence="4">
        <location>
            <begin position="44"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="49628" checksum="7498BFF88EB9905D" modified="2008-04-29" version="1">MTLKQYDPLISTTPASQNWPNSYWASTVQAQQESPSLQRNIQTDVVVIGGGYTGLLTAYYLAEEFNIDVCVVEANAVGFGASGRNAGFVLKGSGRLGYTQIAKKWDLDVAKGIYQEFSEAVERVDSLITSNQIACDPQEKGYLKVAHNPKAMKQLTLASNFITTELGGQAELLSLEQLTENYMHNHQAYGALRLDDGFGINPLKLVLGYKSLVQNTKVSIFENTCIHHWFEEGGKHRLVTSGGEITANRVICAGNAYTPKTFNRRVDDKYLPILSNVIVTEPLTDAELQEAGLKTHQVTMDTRLLKYYYRLLPDNRLLLGGRGAITGKDAQDPIYAQRLKYALAQCFPVLANKAIDYNWTGWIAAAIDDMPHVYQKGGVGYSLGYCGSGVSFSAQAAYRLAQTLVGIKTPDLPLYRQPLPPFPFARMRRVGQWGYYHYAWMRDKYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFH2</accession>
    <name>B1KFH2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.399</ecNumber>
            <ecNumber evidence="7">1.1.1.95</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_3889</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.399" evidence="6"/>
    <dbReference type="EC" id="1.1.1.95" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326477.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3889"/>
    <dbReference type="EnsemblBacteria" id="ACA88147">
        <property type="protein sequence ID" value="ACA88147"/>
        <property type="gene ID" value="Swoo_3889"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3889"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_9_2_6"/>
    <dbReference type="OMA" id="YGNIGTQ"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="340"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA88147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="409" mass="44269" checksum="B47DA9FC12E2D7F1" modified="2008-04-29" version="1">MAKHSLDKDKIKILLLEGVHQSAVDVFKRAGYSNIEYHKASLGEEALKASIKDAHFVGLRSRTQLTEAVLSQAEKLVGIGCFCIGTNQVDLNYAEKLGVPVFNAPFSNTRSVAELVLGEIIMLFRGIPQRNAMAHRGGWLKSATGSYEARGKTLGVIGYGHIGTQLGILAETLGMRVVFFDIEDKLPLGNAQQIHSMQELMSLADVVSLHVPETPQTKEMIGEAELACMKKGSILINASRGTVVDIDALASTLKAEKIAGAAIDVFPVEPKSNDDEFISPLRGLDNVILTPHVGGSTQEAQENIGIEVAGKLAKYSDNGSTMTAVNFPEVSLAQHKDASRLLHIHHNRPGVLIKINQAFAEKGINIAAQYLQTTAEIGYVVMEVDSDQADEALEQMKAIEGTIRTRLLH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFU3</accession>
    <name>SLYX_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein SlyX homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">slyX</name>
        <name type="ordered locus">Swoo_0966</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SlyX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323606.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KFU3"/>
    <dbReference type="SMR" id="B1KFU3"/>
    <dbReference type="STRING" id="392500.Swoo_0966"/>
    <dbReference type="EnsemblBacteria" id="ACA85259">
        <property type="protein sequence ID" value="ACA85259"/>
        <property type="gene ID" value="Swoo_0966"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0966"/>
    <dbReference type="eggNOG" id="COG2900">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180796_4_0_6"/>
    <dbReference type="OMA" id="CQLAFQE"/>
    <dbReference type="OrthoDB" id="2039245at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00715">
        <property type="entry name" value="SlyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007236">
        <property type="entry name" value="SlyX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36508">
        <property type="entry name" value="PTHR36508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04102">
        <property type="entry name" value="SlyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000195857" description="Protein SlyX homolog">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00715"/>
        </source>
    </evidence>
    <sequence length="70" mass="8058" checksum="6CF2519BA2856C56" modified="2008-04-29" version="1">MEQLAQRVEDLEMKLAFQESTIDVLDQQVIKLNDLLAEQQHQLRVLISKLQSVEPSNMATQAEETPPPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG09</accession>
    <name>B1KG09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325058.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2438"/>
    <dbReference type="EnsemblBacteria" id="ACA86716">
        <property type="protein sequence ID" value="ACA86716"/>
        <property type="gene ID" value="Swoo_2438"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2438"/>
    <dbReference type="eggNOG" id="COG3540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000998_3_1_6"/>
    <dbReference type="OMA" id="FQCFINV"/>
    <dbReference type="OrthoDB" id="165142at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD_2" evidence="1">
        <location>
            <begin position="125"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD_2" evidence="1">
        <location>
            <begin position="344"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="492" mass="55755" checksum="6ADBD7C9E994AFE0" modified="2008-04-29" version="1">MANKLLLGPILGLESNTLYTIIFVTDSKMTTPEVNSPTGTTLAVKIGEMGAGTVWRAELNTPLGNARDITYSIKSNGQSVNDARGESQWSFYVPAEHEPPKIGYASCNGFSDYKLMASTDNPYRLWDEMAEQHQEAPFSLLLMGGDQVYADSIWSTVPTLKAWNEGSRKQKIKYTPSKRMIDQLERFYVDLYLDRWNKPAMAKMLSSIPSIMMWDDHDIIDGWGSFPADIQRCDVYKAIFTSAKKLFSLLQVRGDLNKTLLCDQAHSTHFSSFVKFRHFNILTLDNRSERSITEVMCHDHWKDVLTALDTQCTDGDLLILSAVPVVYRDFSFAESALDATPWEEELTDDLKDHWRAKEHEGERLKLIMRLLDNANRRQGKTVMLSGDVHLGGLGIIRDERGGSTNSIHQVISSGIVHPAPTYIQWLGILAVTNDEMEYLDETRLVTANMIKPHGSNKYIRNRNFVTLLEGSDSKLWINWICEGKDKPSYPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG31</accession>
    <name>B1KG31_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2384 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325080.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2461"/>
    <dbReference type="EnsemblBacteria" id="ACA86738">
        <property type="protein sequence ID" value="ACA86738"/>
        <property type="gene ID" value="Swoo_2461"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2461"/>
    <dbReference type="eggNOG" id="COG5642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109353_3_0_6"/>
    <dbReference type="OMA" id="WIEETAV"/>
    <dbReference type="OrthoDB" id="1850771at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011979">
        <property type="entry name" value="Antitox_Xre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024467">
        <property type="entry name" value="Xre/MbcA/ParS-like_toxin-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09722">
        <property type="entry name" value="DUF2384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02293">
        <property type="entry name" value="TAS_TIGR02293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2384" evidence="1">
        <location>
            <begin position="97"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="150" mass="16435" checksum="CD38B445433AACB3" modified="2008-04-29" version="1">MTTMNVFTPTSSAKKVMSFWQLVGVPARGASLYTALHNGLPFEVYAKLAKVSGLEKSELANATVIASATLQRRAKAGKFNKDESDRLYRFAEVYKSALDLFEGNNHDASNWLKSPVRGLGNKRPIEMLSTSAETEAVLNLIGRLEHGVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGH4</accession>
    <name>B1KGH4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3 7">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1009</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15009"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323649.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1009"/>
    <dbReference type="EnsemblBacteria" id="ACA85302">
        <property type="protein sequence ID" value="ACA85302"/>
        <property type="gene ID" value="Swoo_1009"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1009"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_5_1_6"/>
    <dbReference type="OMA" id="RDNQLPW"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000194">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="9">
        <location>
            <begin position="2"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="17608" checksum="98D56193CF97655F" modified="2008-04-29" version="1">MKIALIAAMANNRVIGKDNQMPWHLPEDLRHFKAMTLGKPIVMGRKTFDSIGRPLPGRHNIVISRQEGLKIEGVTCVSSFDAAVSAAGDIEELVVIGGGQLYSATLALADKLYLTEINLDVDGDTHFPSWDDGSWLLLDEEVGVNDKGLEYRFINLVKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGQ5</accession>
    <name>B1KGQ5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aconitate hydratase</fullName>
            <ecNumber evidence="3">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2497</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325115.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2497"/>
    <dbReference type="EnsemblBacteria" id="ACA86774">
        <property type="protein sequence ID" value="ACA86774"/>
        <property type="gene ID" value="Swoo_2497"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2497"/>
    <dbReference type="eggNOG" id="COG1048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013476_2_1_6"/>
    <dbReference type="OMA" id="GRASYMR"/>
    <dbReference type="OrthoDB" id="363064at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012708">
        <property type="entry name" value="2Me_IsoCit_deHydtase_FeS-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670:SF43">
        <property type="entry name" value="PTHR11670:SF43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02333">
        <property type="entry name" value="2met_isocit_dHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="8">
        <location>
            <begin position="70"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="9">
        <location>
            <begin position="658"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="869" mass="95312" checksum="4A063178DEE4AEF9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGR7</accession>
    <name>B1KGR7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4123 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325127.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2509"/>
    <dbReference type="EnsemblBacteria" id="ACA86786">
        <property type="protein sequence ID" value="ACA86786"/>
        <property type="gene ID" value="Swoo_2509"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2509"/>
    <dbReference type="eggNOG" id="ENOG502ZB4R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_911684_0_0_6"/>
    <dbReference type="OMA" id="RQWSLVA"/>
    <dbReference type="OrthoDB" id="610969at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025391">
        <property type="entry name" value="DUF4123"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13503">
        <property type="entry name" value="DUF4123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4123" evidence="1">
        <location>
            <begin position="28"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="308" mass="35415" checksum="432F6F4D52AAABFF" modified="2008-04-29" version="1">MTEKKHSNVQIADIDSEMWLSTIAEGGCFILAESAINDEVPSLAENINGFSLEYSRLYWDETGRIHASISPYLINVTEDNWPMLKEKVCHQAHWGVGIQLEWYMNAYTPAQQLTELLSHLREWTWLESQNGESRLLRLSDWKVLSTLMQASSNDEVSAIFGPIAQFVSLEGETLSAMTRLVKQKSEIPQRTPQQLSEQQWHALEHMEQGDQFAAYKDHLKTHHKETLSWPKERLHSFVEQQTKVANDQGFSNRQDTVKFLSLSLIFGQTFVSQEWAKKVLKAKQEGTKTKMEKLYQAALNELDKEVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHA0</accession>
    <name>B1KHA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323754.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1115"/>
    <dbReference type="EnsemblBacteria" id="ACA85408">
        <property type="protein sequence ID" value="ACA85408"/>
        <property type="gene ID" value="Swoo_1115"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1115"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_2_6"/>
    <dbReference type="OMA" id="RRMDTGQ"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="37"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="502" mass="53689" checksum="368CD3E6D90D0381" modified="2008-04-29" version="1">MSTPTNHQEWQTLAETLLAQGVKADAYIEGEYRPAVSGERFDCVSPIDGRVLCQVASCSLEDANIAVKSAREAFDSGVWSQLPPVKRKQVMIRFAELLEANKDELALLETLDMGKPIRYSGAVDVMGAARAISWSGEAIDKIYDEIAPTAHNEIGMITREPVGVVAAIVPWNFPILMACWKLGPALATGNSVILKPSEKSPLTALRMAQIALEAGIPKGVLNVLPGFGHTVGKALALHMDVDTIVFTGSTKIAKQLMIYAGESNMKRVWLEAGGKSPNIVFNDAPDLQKAAEAAATAIAFNQGEVCTAGSRLLVEAGVKDELLSLIAKEMQAWRPGHPLDPDTTCGAVVDNQQLDNVLKYIRAGVAEGAELVHGGSQVMAETGGAYVEPTIFSNVSNGMTIAKEEIFGPVLSVITFDGMEEAISIGNDSIYGLAAGVWTSNISKAHKTAKALRSGMVWINHYDGGDMTAPFGGYKQSGNGRDKSLHAFDKYTEIKATWIALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHC4</accession>
    <name>B1KHC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323778.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1139"/>
    <dbReference type="EnsemblBacteria" id="ACA85432">
        <property type="protein sequence ID" value="ACA85432"/>
        <property type="gene ID" value="Swoo_1139"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1139"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100937_0_0_6"/>
    <dbReference type="OMA" id="NGDTAMF"/>
    <dbReference type="OrthoDB" id="1030262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045617">
        <property type="entry name" value="DUF6445"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20043">
        <property type="entry name" value="DUF6445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="27521" checksum="1ACA43A992E35399" modified="2008-04-29" version="1">MNTQTSLIRISSLSPQVIKIGEEATPIIIIDDFAEDLAPLLSFAHEAIFKQDNGSYYPGVRARLPKPYAIEVINQVFQLIYDVYRIPHHLRITPHIYSFSLITQTPESLQPLQCLPHFDTKEPNYFAILHYLNSAPHGATAFFKHKPTGYERINSERIDEYFNKAQVCLDEIKRQTPQYFTHSNEHYEIYHQVEYRPNRLIIYPGNLLHSTLVDLDTDIDSKPETGRLTSNIFINFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL9</accession>
    <name>B1KHL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325244.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2627"/>
    <dbReference type="EnsemblBacteria" id="ACA86904">
        <property type="protein sequence ID" value="ACA86904"/>
        <property type="gene ID" value="Swoo_2627"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2627"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034273_0_0_6"/>
    <dbReference type="OMA" id="YYLMEYV"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="271"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="576" mass="64779" checksum="A427889C8C794ECE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHU3</accession>
    <name>B1KHU3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Cytochrome b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">Swoo_4165</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="14">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the cytochrome b family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326750.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4165"/>
    <dbReference type="EnsemblBacteria" id="ACA88421">
        <property type="protein sequence ID" value="ACA88421"/>
        <property type="gene ID" value="Swoo_4165"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4165"/>
    <dbReference type="eggNOG" id="COG1290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031114_3_0_6"/>
    <dbReference type="OMA" id="RFFAFHF"/>
    <dbReference type="OrthoDB" id="262439at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00284">
        <property type="entry name" value="Cytochrome_b_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030689">
        <property type="entry name" value="Cytochrome_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038885">
        <property type="entry name" value="COB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="SSF81648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="17">
        <location>
            <begin position="5"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_CTER" evidence="18">
        <location>
            <begin position="227"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACA88421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="45946" checksum="F204F226FFC54066" modified="2008-04-29" version="1">MVKNIVDWIDARIPMTATYNRHVGQYATPTNFNFWYFFGSLAMLVLVNQLLTGIWLTMNYVPTAEGAFASIEYIMRDVEYGWLLRYMHSTGASAFFVVIYLHMFRGLIYGSYQKPRELLWLFGMLIFLVLMAEAFMGYLLPWGQMSYWGAQVIISLFGAIPVIGDDLTLWIRGDFVVSGATLNRFFALHVIALPLVLVVLVFLHLIALHEVGSNNPDGIEIKKNKDENGWPVDGIPFHPYYTVKDIMGVAGFLIIFCYVLFFMPEGGGYFLEKPNFEAANPMKTPEHIAPVWYFTPFYAILRAIPDKLLGVVGMGLAIAVLFVLPWLDRCKVKSIRYRSMVHKLNISQFAVSFIVLGYLGAVPATPALTIAARIFTLTYFGFFLALWIYSKNEKTKPVPERLTH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV0</accession>
    <name>MUTL_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mutL</name>
        <name type="ordered locus">Swoo_4172</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326757.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHV0"/>
    <dbReference type="SMR" id="B1KHV0"/>
    <dbReference type="STRING" id="392500.Swoo_4172"/>
    <dbReference type="EnsemblBacteria" id="ACA88428">
        <property type="protein sequence ID" value="ACA88428"/>
        <property type="gene ID" value="Swoo_4172"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4172"/>
    <dbReference type="eggNOG" id="COG0323">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004131_5_1_6"/>
    <dbReference type="OMA" id="FTHIDEW"/>
    <dbReference type="OrthoDB" id="764332at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000096687" description="DNA mismatch repair protein MutL">
        <location>
            <begin position="1"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="614" mass="68598" checksum="AB093712A55BD2D4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHX5</accession>
    <name>B1KHX5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326782.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4197"/>
    <dbReference type="EnsemblBacteria" id="ACA88453">
        <property type="protein sequence ID" value="ACA88453"/>
        <property type="gene ID" value="Swoo_4197"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4197"/>
    <dbReference type="eggNOG" id="COG5345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_857250_0_0_6"/>
    <dbReference type="OMA" id="PMILNGS"/>
    <dbReference type="OrthoDB" id="1067709at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016936">
        <property type="entry name" value="UCP029693"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10095">
        <property type="entry name" value="DUF2333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029693">
        <property type="entry name" value="UCP029693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="35975" checksum="49BB69072B512EFA" modified="2008-04-29" version="1">MQMTWKKGAGIAVLILLIGYFISVWWSIEPDTIKPQELRSQSNHEVVGYATTTSLILTMETLLGKSGGWLSNDVLPPSIFMDNMPAFEFGALEQARDLALIMRKEFSRSQSQSAADADLLAAHSKLNIEHTSWLVPSAEGEYKDAIKLLKVYRAKIADVNNQDAQFYARADNLNEWLKEVQKRLGSMSQRLSASVGQERLNTDLAGDSEASQSTPNLASMQIKTSWWKIDDVFYETRGATWALLNFMKAIEVDFADVLRKKNAEVSLQQIIRELEETQQAVWSPIVLNGSGFGVVANHSLVMANYISRANAAVIDLTNLLTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI28</accession>
    <name>B1KI28_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323852.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1213"/>
    <dbReference type="EnsemblBacteria" id="ACA85506">
        <property type="protein sequence ID" value="ACA85506"/>
        <property type="gene ID" value="Swoo_1213"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1213"/>
    <dbReference type="eggNOG" id="ENOG50339BD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1625932_0_0_6"/>
    <dbReference type="OMA" id="LMDYQTM"/>
    <dbReference type="OrthoDB" id="1508892at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766638" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="31"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="18057" checksum="87BC67DCCF4B4244" modified="2008-04-29" version="1" precursor="true">MLRYLCLILVFISLPSTANNGEMPLEQQLAVRYITALTDHDYKTLISFYNRESVFNDRTAGKKYTGKRHILSFLKRAHQGVLEYGFNIEHMFNSGSLVVMIGNYHYKGPGEQFGKPGKIIDLAIPGVTTVKLDMNTHRVKEHEDLMDYQTMADQLAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI51</accession>
    <name>B1KI51_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1237</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323875.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1237"/>
    <dbReference type="EnsemblBacteria" id="ACA85529">
        <property type="protein sequence ID" value="ACA85529"/>
        <property type="gene ID" value="Swoo_1237"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1237"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_6"/>
    <dbReference type="OMA" id="RIAINQC"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014286">
        <property type="entry name" value="RNA_pol_sigma70_RpoE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02939">
        <property type="entry name" value="RpoE_Sigma70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="135"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="192" mass="21903" checksum="854CD2C40DEDAC2B" modified="2008-04-29" version="1">MSGQISDQQLVERVQQGDKNAFNLLVQKYQNKVMSLISRYVRNQADVGDVAQEAFIKAYRALPNFRGESAFYTWLYRIAVNTAKNHLVAQGRRAPANDIDAEEAEYYDGSDALKEFASPERLMMSDQIQKVVFDTLDTLPEELKMAISLRELDGMSYEEIANVMDCPVGTVRSRIFRAREAIDKKLQPLLEQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI70</accession>
    <name>TRMD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmD</name>
        <name type="ordered locus">Swoo_1256</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323894.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI70"/>
    <dbReference type="SMR" id="B1KI70"/>
    <dbReference type="STRING" id="392500.Swoo_1256"/>
    <dbReference type="EnsemblBacteria" id="ACA85548">
        <property type="protein sequence ID" value="ACA85548"/>
        <property type="gene ID" value="Swoo_1256"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1256"/>
    <dbReference type="eggNOG" id="COG0336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047363_0_1_6"/>
    <dbReference type="OMA" id="ILCGHYK"/>
    <dbReference type="OrthoDB" id="525632at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000130209" description="tRNA (guanine-N(1)-)-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <sequence length="248" mass="27397" checksum="C1B628024A2689A3" modified="2008-04-29" version="1">MWLGVVTLFPEMFRAVTDFGVTGRAVNKGLLELQTWNPRDFTHDKHKTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGDSAKVIYLSPQGRKLTQQGVEELAKSDSLILVCGRYEGVDERIIQTEVDEEWSIGDYVLSGGELPAMTLIDSVSRLVPGVLGKQASAEQDSFSDGLLDCPHYTRPETLDGLDVPAVLLSGNHEHIRRWRLQQSLGRTLLRRPELLENLALTDEQTKLLAQFVDSTNECG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB8</accession>
    <name>B1KIB8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325308.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2693"/>
    <dbReference type="EnsemblBacteria" id="ACA86969">
        <property type="protein sequence ID" value="ACA86969"/>
        <property type="gene ID" value="Swoo_2693"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2693"/>
    <dbReference type="eggNOG" id="COG0327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037423_3_0_6"/>
    <dbReference type="OMA" id="HGLFWRG"/>
    <dbReference type="OrthoDB" id="502462at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="PTHR13799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="250" mass="27449" checksum="D06CEC34A0F5F661" modified="2008-04-29" version="1">MTRSELSQYLSEFLQVAKYKDYAPNGLQVEGREQIATIVTGVSACQALIDKAIELNADAILVHHGFFWKGEPQVITGMKQRRIKALLSQDINLYGYHLPLDGHPKLGNNAELARRLDITGAESLEGVAQGLVWQGRLDKPMSAKAFSARLAQVLNREALHIGDEEGEIQTLAWCSGGAQDYIDIASELGVDAFISGEVSERTYHSAIELGVHYFAAGHHATERYGIQALGEHLASEFGLTHHFVDIDNPV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII1</accession>
    <name>RS9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsI</name>
        <name type="ordered locus">Swoo_4221</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012141096.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KII1"/>
    <dbReference type="SMR" id="B1KII1"/>
    <dbReference type="STRING" id="392500.Swoo_4221"/>
    <dbReference type="EnsemblBacteria" id="ACA88477">
        <property type="protein sequence ID" value="ACA88477"/>
        <property type="gene ID" value="Swoo_4221"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4221"/>
    <dbReference type="eggNOG" id="COG0103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046483_2_1_6"/>
    <dbReference type="OMA" id="QWKINGR"/>
    <dbReference type="OrthoDB" id="1766414at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000128175" description="30S ribosomal protein S9">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <sequence length="130" mass="14537" checksum="240019CCE7AB24AA" modified="2008-04-29" version="1">MAATQYYGTGRRKTSTARVFAKVGTGNIVVNQLPLDQYFGRETSRMVVRQPLELVEMTDKLDIFVTVKGGGNTGQAGAIRHGITRALMELDESLRPSLRAAGFVTRDARKVERKKVGLRKARRKPQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII5</accession>
    <name>B1KII5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="4">3.4.21.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.</text>
            <dbReference type="EC" id="3.4.21.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326808.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4225"/>
    <dbReference type="EnsemblBacteria" id="ACA88481">
        <property type="protein sequence ID" value="ACA88481"/>
        <property type="gene ID" value="Swoo_4225"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4225"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_1_1_6"/>
    <dbReference type="OMA" id="IIGINRQ"/>
    <dbReference type="OrthoDB" id="741829at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02037">
        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010602340" description="Periplasmic serine endoprotease DegP-like" evidence="4">
        <location>
            <begin position="27"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="257"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="360"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="450" mass="46420" checksum="5C0888663C03579C" modified="2008-04-29" version="1" precursor="true">MKTKLSLLSAALLTASLTLTPAISQAAIPMAVNGESIPSLAPMLERTTPAVVAVAVEGTHVSKQKLPDAFRYFFGPNAPQEQVQERPFRGLGSGVIIDANKGYIVTNNHVIDGADEILIGLHDGREVEAKLIGADAESDIALLQIKAKNLVAVKRADSDELKVGDFAVAIGNPFGLGQTVTSGIVSAMGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGDLIGINTAIVAPGGGNVGIGFAIPANMVNNLVDQIIEHGEVRRGVLGVSGRDLTSELAQAFGLDTQHGGFVDQVMEDSAAEDAGIKAGDIIVSVNGRKIKSFQELRAKVATMGAGAKVKFGLIRDGDSKTVSATLGEASQTTEASAGAVHPMLAGAALENGDDGVEITDIAQNSPAAASGLRKGDVIVGVNRSSIDDLNSLKAKLKEQQGTVALKIQRGHSSLFLVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU1</accession>
    <name>B1KIU1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type IV pilus assembly protein PilX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323935.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1297"/>
    <dbReference type="EnsemblBacteria" id="ACA85589">
        <property type="protein sequence ID" value="ACA85589"/>
        <property type="gene ID" value="Swoo_1297"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1297"/>
    <dbReference type="eggNOG" id="COG4726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149130_0_0_6"/>
    <dbReference type="OMA" id="INCRRVE"/>
    <dbReference type="OrthoDB" id="1765497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="14664" checksum="3FC32EFBE0193E14" modified="2008-04-29" version="1" precursor="true">MKKQEGMILFFSLIVLVIMTVIGVALAVNSTQSIRMAGAGSERVEAMAAAHGALDSVIDSNQGVALANLTGEMNAGTMLGVASTITPLQLDDVSCQRSANASSSNLISCRRSEITSVSSFGRNNMGRLTVVGGVEQEVLTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIW9</accession>
    <name>B1KIW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323963.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1325"/>
    <dbReference type="EnsemblBacteria" id="ACA85617">
        <property type="protein sequence ID" value="ACA85617"/>
        <property type="gene ID" value="Swoo_1325"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1325"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018914_1_0_6"/>
    <dbReference type="OMA" id="IYYANLY"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="614" mass="69513" checksum="3940A1359A762681" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ10</accession>
    <name>B1KJ10_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325366.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2754"/>
    <dbReference type="EnsemblBacteria" id="ACA87030">
        <property type="protein sequence ID" value="ACA87030"/>
        <property type="gene ID" value="Swoo_2754"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2754"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_34_9_6"/>
    <dbReference type="OMA" id="IQLYPSY"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="14310" checksum="F7B1B7C313C6DB3A" modified="2008-04-29" version="1">MYIRIAIDDDLNALATLFDEYRMCLGRESNLKDCKAFIQARLFENDSVIFLAFKSDVPVGFIQLFPSYSTILLKPLWYFDDLFVLEDYRGSGIATALVAKAKELADEAQVVAVRRDNIEGEGFLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ93</accession>
    <name>B1KJ93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/solute symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2838</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325449.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2838"/>
    <dbReference type="EnsemblBacteria" id="ACA87113">
        <property type="protein sequence ID" value="ACA87113"/>
        <property type="gene ID" value="Swoo_2838"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2838"/>
    <dbReference type="eggNOG" id="COG4147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_8_2_6"/>
    <dbReference type="OMA" id="GTTWVQM"/>
    <dbReference type="OrthoDB" id="278483at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019899">
        <property type="entry name" value="Na/solute_symporter_VC_2705"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03648">
        <property type="entry name" value="Na_symport_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="527"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="572" mass="61116" checksum="70800BB9E26C241A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG8</accession>
    <name>B1KJG8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase U62 modulator of DNA gyrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326966.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4388"/>
    <dbReference type="EnsemblBacteria" id="ACA88640">
        <property type="protein sequence ID" value="ACA88640"/>
        <property type="gene ID" value="Swoo_4388"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4388"/>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026425_0_0_6"/>
    <dbReference type="OMA" id="LYRKSTF"/>
    <dbReference type="OrthoDB" id="958356at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="124"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="239"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="47779" checksum="60E2779632F9A77B" modified="2008-04-29" version="1">MTTPSLDLELDLLKDAVSMALDYANKLGTTAAEVAISKQQGLSVSTRLKEVETVEFNKDGALGITLFRDGCKGSSSTSDLSPEAIKLAVKAADDIARFTSSDPNNGLAEAELMATEFPDLELYHPQDISAEQLTELAARSEEAALNVDSRITNSDGASANAHTGLKVYGNSHGFLNGFSSSRYSLSCVVIGESNGNMQRDYDYTISRNFNELLSAEEVGQKASEKTLGRLDSRKIATTELPVLLAPDIATGLMGHLVSAISGSSLYRKSSFLLDSIDTQIFPDWFSIEEQPHLKGALASAIYDSEGVATQDRSIIKDGVLSTYLLTSYSARKLGLKNTGHAGGIYNWTLSHTGQTFDELVKQMGTGVIVTEVMGQGVNAVTGDYSRGAAGFYVENGVILYPVEEFTIAGNLKDMFQNIVAVSSDRDLRSSIRTGGILLSDMKIAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJN3</accession>
    <name>B1KJN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multicopper oxidase type 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324052.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1414"/>
    <dbReference type="EnsemblBacteria" id="ACA85706">
        <property type="protein sequence ID" value="ACA85706"/>
        <property type="gene ID" value="Swoo_1414"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1414"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064932_1_0_6"/>
    <dbReference type="OMA" id="MFHPHQD"/>
    <dbReference type="OrthoDB" id="971126at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764575" evidence="2">
        <location>
            <begin position="26"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="41"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="190"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="360" mass="40700" checksum="BC399F5182EAEE02" modified="2008-04-29" version="1" precursor="true">MRINLIPYKVWILSSLLLFSQIVAAQTLEFEMTIDEMVAEVTPGFSNKVWAFNGQVPGPLIRAKEGDRLKITVHNNSTLAHTVHWHGTLQTNSWKMDGVPGVTQKAIEPGESFVYDFIVDRPGSLWYHCHVNVPEHVGLRGMWGPMIIDPKDPTDIEKTVTKEAIMMVSGWNSEVAMEYGKGGHPQELNDYFSINGKSFPSTQPLRVKEGDVLRIRLYAATIETAYHLHGHDVLVTHKDGLPLDSPYWADVVYVPSGGRVDVIVKMNNPGIWINHDHIERHTSNAGKMPGGAVTIIEYEGVETEDWYKWKDKKYQADFYMSETMKKGSGLHNISIFKATAPKSDRTKKKRKRKKSASKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT1</accession>
    <name>B1KJT1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2843"/>
    <dbReference type="EnsemblBacteria" id="ACA87118">
        <property type="protein sequence ID" value="ACA87118"/>
        <property type="gene ID" value="Swoo_2843"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2843"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_11_1_6"/>
    <dbReference type="OMA" id="MVHRDDA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="271" mass="29427" checksum="D6FCB5A088D41D7D" modified="2008-04-29" version="1" precursor="true">MKINTVSIVGCGWFGLPLAKELVNQGFVVSGSKRSAEDALALELDNISGFVLDLDNSNDNQAHLNVKLHTDAIIINIPPSIRKSPGAYIRRLEQLKRLIAAHQYQKLIFISTTGVYPSCGKLVTEQDAQAHSEASEVLLQAESLFNQASNACVIRFAGLVGPARHPGRFLAGKTELAGADSPVNIVHLDDCVAAVTCVLSSDKVSDTYNLCAPEHPTRKEFYTQMARSLSLVEPEFGDIAQAGKVIDGSKISTELGFEYQHQDPMKICFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJY0</accession>
    <name>B1KJY0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroneopterin aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325503.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2892"/>
    <dbReference type="EnsemblBacteria" id="ACA87167">
        <property type="protein sequence ID" value="ACA87167"/>
        <property type="gene ID" value="Swoo_2892"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2892"/>
    <dbReference type="eggNOG" id="COG1539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112632_0_0_6"/>
    <dbReference type="OMA" id="VIHYCAD"/>
    <dbReference type="OrthoDB" id="1858654at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006760">
        <property type="term" value="P:folic acid-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00534">
        <property type="entry name" value="DHNA_DHNTPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="PTHR42844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="1">
        <location>
            <begin position="8"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="123" mass="14407" checksum="BD4F1551FF168B07" modified="2008-04-29" version="1">MKPEIAVIRIKNLRLRTFIGIKDDETQNKQDVLINAEIHYCAEKARNSDNMDDALNYRTITKKIIALVEHNRFFLLEHLTGQVLDITREHDWVDFAKVEIDKPHALRFADSVSMELSYHKNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK49</accession>
    <name>B1KK49_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sporulation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327006.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4428"/>
    <dbReference type="EnsemblBacteria" id="ACA88680">
        <property type="protein sequence ID" value="ACA88680"/>
        <property type="gene ID" value="Swoo_4428"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4428"/>
    <dbReference type="eggNOG" id="COG3087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058902_1_0_6"/>
    <dbReference type="OMA" id="YIMQCGA"/>
    <dbReference type="OrthoDB" id="1741144at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPOR" evidence="2">
        <location>
            <begin position="109"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21541" checksum="35EDEDA374198F9C" modified="2008-04-29" version="1" precursor="true">MSNRDYANRKPAKGRAKSTRRKGKAPAPRRFPLLLLLVTLSLLGGFGYFLWSINNSADTPQAVVVEQPKKTVVKKDPNDLPPKPKEEWTYQQALENKKVEVDIPDAEKAKPARPYQMQCGSFRTQSQAEEMKAVIAFQGLTANIRKVKGTTGDWYKVSLGPFDRKREVERKRHTLQRAGINGCIILFWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK82</accession>
    <name>B1KK82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88713">
        <property type="protein sequence ID" value="ACA88713"/>
        <property type="gene ID" value="Swoo_4461"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4461"/>
    <dbReference type="eggNOG" id="ENOG5033DVI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_210182_0_0_6"/>
    <dbReference type="OMA" id="KAMQAQR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045493">
        <property type="entry name" value="DUF6435"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20027">
        <property type="entry name" value="DUF6435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="56" mass="6451" checksum="C01FB124B7994F46" modified="2008-04-29" version="1">MFSIFKRDPAKKLKKQYFAKLEQAMLAQRKGDIRTYSLLTAEAGEIDKPISNLMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK93</accession>
    <name>B1KK93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327050.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4473"/>
    <dbReference type="EnsemblBacteria" id="ACA88724">
        <property type="protein sequence ID" value="ACA88724"/>
        <property type="gene ID" value="Swoo_4473"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4473"/>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_1_3_6"/>
    <dbReference type="OMA" id="DCIACKY"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="131"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="25601" checksum="5FA02947D67FE0AD" modified="2008-04-29" version="1" precursor="true">MSENLERRRFLKGLGASSLILTPLVGCSSVKEKEDTNKPHYVMVFDQNKCVGCGECKEACNKANHLPEGKSRLLMEEQSSAVEGQPCPHCGKTGDCGCQRKFVRVSCQQCKNAPCVTVCPTGAAHRDEKTGIVTMDAAKCAGCKYCIGACPYDARFINKETDVADNCDFCLNSKLAIGELPACVQQCRYDALIFGDANDPTSYVSKLLAVKDSVRIKPGFGTEPSLRYIPIVKLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH8</accession>
    <name>B1KKH8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324164.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1530"/>
    <dbReference type="EnsemblBacteria" id="ACA85818">
        <property type="protein sequence ID" value="ACA85818"/>
        <property type="gene ID" value="Swoo_1530"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1530"/>
    <dbReference type="eggNOG" id="COG4319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119548_1_0_6"/>
    <dbReference type="OMA" id="TDATENW"/>
    <dbReference type="OrthoDB" id="1481875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764613" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="38"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="18208" checksum="9ADCCE08AE6F2780" modified="2008-04-29" version="1" precursor="true">MRANFKLSALKPFISALLIIAASINTAAFAKSTDHNAEQVLDKLHQAASDGDWDCYFSLYLPDAIFIGTDANEHWTMEKFQQYARPTKGWTYTLKSRKLNTMQKLDKVIVFDELLDSQSYGVSRGTGTLVLTDMGWKVAQYHLSFPIPNAIAKEITATIKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKJ6</accession>
    <name>B1KKJ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325549.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2940"/>
    <dbReference type="MEROPS" id="S09.071"/>
    <dbReference type="EnsemblBacteria" id="ACA87213">
        <property type="protein sequence ID" value="ACA87213"/>
        <property type="gene ID" value="Swoo_2940"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2940"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_2_1_6"/>
    <dbReference type="OMA" id="NDYAGKE"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764615" evidence="2">
        <location>
            <begin position="26"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="463"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="689" mass="77195" checksum="A8E37C7996D21FC7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKS8</accession>
    <name>B1KKS8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3024"/>
    <dbReference type="EnsemblBacteria" id="ACA87295">
        <property type="protein sequence ID" value="ACA87295"/>
        <property type="gene ID" value="Swoo_3024"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3024"/>
    <dbReference type="eggNOG" id="ENOG5031H5D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3332916_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="39" mass="4624" checksum="B58F9B96584343FF" modified="2008-04-29" version="1">MFDSIMKALGLINKPERRRVQLPEGLNHLEVIPAKVWWH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY6</accession>
    <name>MRAZ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName>Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mraZ</name>
        <name type="ordered locus">Swoo_4542</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MraZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327118.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKY6"/>
    <dbReference type="SMR" id="B1KKY6"/>
    <dbReference type="STRING" id="392500.Swoo_4542"/>
    <dbReference type="EnsemblBacteria" id="ACA88792">
        <property type="protein sequence ID" value="ACA88792"/>
        <property type="gene ID" value="Swoo_4542"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4542"/>
    <dbReference type="eggNOG" id="COG2001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107907_2_0_6"/>
    <dbReference type="OMA" id="RGQERCL"/>
    <dbReference type="OrthoDB" id="1684767at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000191335" description="Transcriptional regulator MraZ">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB 1" evidence="2">
        <location>
            <begin position="5"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB 2" evidence="2">
        <location>
            <begin position="81"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <sequence length="152" mass="17541" checksum="E1007435CC3FE584" modified="2008-04-29" version="1">MFRGASAINLDTKGRVAIPKRYREPLHVEYNSQLVITVDIQSACLLLYPLDEWSKIEAKLLLLSDTLPAERAMKRMLLGYAHECELDGNGRLLLPLPLRQYANLGKRAMLVGQLNKFELWDETAWQHQIEQSRETIQDEEFAENIRLADFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH4</accession>
    <name>B1KLH4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flagellar secretion chaperone FliS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1613</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the FliS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324245.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1613"/>
    <dbReference type="EnsemblBacteria" id="ACA85899">
        <property type="protein sequence ID" value="ACA85899"/>
        <property type="gene ID" value="Swoo_1613"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1613"/>
    <dbReference type="eggNOG" id="COG1516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080373_1_0_6"/>
    <dbReference type="OMA" id="EFRDTWK"/>
    <dbReference type="OrthoDB" id="1730695at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16098">
        <property type="entry name" value="FliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003713">
        <property type="entry name" value="FliS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036584">
        <property type="entry name" value="FliS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34773">
        <property type="entry name" value="PTHR34773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02561">
        <property type="entry name" value="FliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039090">
        <property type="entry name" value="Flis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101116">
        <property type="entry name" value="SSF101116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00208">
        <property type="entry name" value="fliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15123" checksum="5900EE986BB5F172" modified="2008-04-29" version="1">MRKSLQSYRKVSVESEISVASPHRIIQMMFEGALQRLAQSRYAIENNDIANKGIYIGKAVGLITGLNNSLNMDAGGDIASNLSDLYDFMLRRISEANMNNDIQAIDDVSDILKTIKEGWDAIPPEKHHMASHSEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP9</accession>
    <name>B1KLP9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein TonB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_3075</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell inner membrane</location>
            <topology evidence="1 9">Single-pass membrane protein</topology>
            <orientation evidence="1 9">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325682.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3075"/>
    <dbReference type="EnsemblBacteria" id="ACA87346">
        <property type="protein sequence ID" value="ACA87346"/>
        <property type="gene ID" value="Swoo_3075"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3075"/>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108529_1_0_6"/>
    <dbReference type="OMA" id="DTNMSFN"/>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031992">
        <property type="term" value="F:energy transducer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003538">
        <property type="entry name" value="TonB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01374">
        <property type="entry name" value="TONBPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="123"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="40"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22352" checksum="DAE585469182A319" modified="2008-04-29" version="1" precursor="true">MLRGIVSLILGAAVTFALFVFMAFLVGGGAKRADTKTDSPIIEISMDKQDTKVQDKPRVKPKPPTPPEQPPLPDTPPPDSSSDIDTNMSFNMGGVAAGSANTGFKLGNMMTRDGDATPIVRIEPQYPIAAARDGKEGWVQLSFTINELGGVEDVKIIKAEPKRLFNKEARRALKKWKYKPKIVDGKALKQPGMTVQLDFTLDKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ0</accession>
    <name>B1KLQ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein ExbD/TolR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3076</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325683.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3076"/>
    <dbReference type="EnsemblBacteria" id="ACA87347">
        <property type="protein sequence ID" value="ACA87347"/>
        <property type="gene ID" value="Swoo_3076"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3076"/>
    <dbReference type="eggNOG" id="COG0848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085305_3_0_6"/>
    <dbReference type="OMA" id="MIDIMMF"/>
    <dbReference type="OrthoDB" id="1537812at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="14638" checksum="6697265EFBDB83CA" modified="2008-04-29" version="1">MARKKHASVDDEAQVDMTPMLDIVFIMLIFFIVTTSFIKPSGLDYKKPEASTATQQKSANIFIGVSKTGVIKMENRQVDIERVTANVERMLAEAPEAAVLIEADQEAEHGLVVKVMDSVKKAGIDKISVSAGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS7</accession>
    <name>B1KLS7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325710.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3103"/>
    <dbReference type="EnsemblBacteria" id="ACA87374">
        <property type="protein sequence ID" value="ACA87374"/>
        <property type="gene ID" value="Swoo_3103"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3103"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_3_6"/>
    <dbReference type="OMA" id="RKEWYAN"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="96"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="37536" checksum="AACE5CC385EE1D8C" modified="2008-04-29" version="1" precursor="true">MARYLLRRLNLFLATSLVLFAVLFMVTSQFPVEQRFALTGIQSPSAEQITQIEEDYKLNSGKFNQFIAYLQQRLGGNLGISATSQRPVADELASVLPASFELAAVAGFLALAFGLPLGILASLSRHKVTQHTIMAITLTGYSIPVFWLGLTLSLWFGVQLGWLPISGRLNLLYEIEPVTGFILIDTLISSSPYSTSAFLDALLHIILPAVTLAVLPFTVVVRITRAAMISIMEQTYIKAAEARGLHTSRIVLRHALPNALIPVIKNLGLMLGTFASYAIVVEVIFSWPGVGAWLVSGIYQRDYTAIQGGVLAVALIIIFLSIMIEVLHTTMNPLSRKELYASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLT4</accession>
    <name>B1KLT4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Histone family protein DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325717.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3110"/>
    <dbReference type="EnsemblBacteria" id="ACA87381">
        <property type="protein sequence ID" value="ACA87381"/>
        <property type="gene ID" value="Swoo_3110"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3110"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_2_6"/>
    <dbReference type="OMA" id="PAHEGIN"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="90" mass="9403" checksum="9760513B3A973A88" modified="2008-04-29" version="1">MNKSELIEKIASGADISKAAAGRALDSFIEAVTDGLKDGDKISLVGFGTFEVRQRAERTGRNPQTGAEIKIAAANIPAFKAGKALKDAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV6</accession>
    <name>B1KLV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88836">
        <property type="protein sequence ID" value="ACA88836"/>
        <property type="gene ID" value="Swoo_4586"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4586"/>
    <dbReference type="eggNOG" id="ENOG502ZJTT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1019001_0_0_6"/>
    <dbReference type="OMA" id="EKEDCYR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="273" mass="31209" checksum="6989EC02D1D2EAC2" modified="2008-04-29" version="1">MAWQNAQAVYTNVKFNRGNVDKSTQLMKWILFWVFIVLFSLAVLGTLGVVFLGFGTPTEAEREWLVKGLILEVAACIVALFYSIFGLKPESGKQNLNVEDFENRLTELESKVFLTVKEIDSNTAELCARKDDSSSSPSKDFMHQMYPFLARIDEYDTPPPFDVDEYNTSPSYTEIDADISSAKPFDKEHREKSYFGLKVQWKCAYKGIAEKEDCYRIRLDTERPLYGAYIEVSKEKDISKLKFLDEGHPMWVCGEIIDLSGSNVELANANFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM00</accession>
    <name>B1KM00_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327205.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4630"/>
    <dbReference type="EnsemblBacteria" id="ACA88880">
        <property type="protein sequence ID" value="ACA88880"/>
        <property type="gene ID" value="Swoo_4630"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4630"/>
    <dbReference type="eggNOG" id="COG4916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962766_0_0_6"/>
    <dbReference type="OMA" id="SPWVQRE"/>
    <dbReference type="OrthoDB" id="854145at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="291" mass="32741" checksum="84EE36F7E020F790" modified="2008-04-29" version="1">MTISVFLSHNHSDKDFIRKLARDLESHGVRYWLDEAEMKIGDSLIQKIREGIDSVDFFAVVLSPNSVEAPWVVNELDVAMNQQINGKPIKVLPILLKECELPGFLVGKLYGDFQNEAQYEDSFRILINSIGLVFNKSVMNSERSSNSLGTALDKAFLKSLPLMSKPFHRPFQYMGMPIHKAEAEVGAAANSVGNIIVENDDCRMLLEAEGNFISYVEVDLKATAPHYQNQEFDSEPVLGALSIGLTELDLERKKTHYHTYYDHRRKLKVSVSCLGDGEPLTVAFSSKYYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM90</accession>
    <name>B1KM90_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Cell division ATP-binding protein FtsE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ftsE</name>
        <name evidence="9" type="ordered locus">Swoo_0202</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a membrane-associated complex with FtsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322852.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0202"/>
    <dbReference type="EnsemblBacteria" id="ACA84503">
        <property type="protein sequence ID" value="ACA84503"/>
        <property type="gene ID" value="Swoo_0202"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0202"/>
    <dbReference type="eggNOG" id="COG2884">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="CHNLETA"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005286">
        <property type="entry name" value="Cell_div_FtsE_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02673">
        <property type="entry name" value="FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="231" mass="25433" checksum="185637EC94F8B2B0" modified="2008-04-29" version="1">MIQFEQVSKVYPGGQKALSDVNFHLQRGEMAFLTGHSGAGKSTLLKLITVIERANAGRVLINGHNIADLSAKDVPYLRRDIGMIFQNHHLLMEKSVFDNVALPLVIEGFSHGEIKKRVHASLDMVGLYGKERHKPIMLSGGEQQRVGIARAIVNKPPLLLADEPTGNLDPKLSMDILRLFETFNDSGTTVLIATHDLGLIARMKYRTLTLKQGHVLGSDELSASTTYSPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB4</accession>
    <name>B1KMB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenylacetic acid degradation protein paaN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0226</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322876.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0226"/>
    <dbReference type="EnsemblBacteria" id="ACA84527">
        <property type="protein sequence ID" value="ACA84527"/>
        <property type="gene ID" value="Swoo_0226"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0226"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025047_0_0_6"/>
    <dbReference type="OMA" id="DTFYAHM"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011966">
        <property type="entry name" value="PaaN-DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02278">
        <property type="entry name" value="PaaN-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="11"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="3">
        <location>
            <begin position="540"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="683" mass="74061" checksum="E992399B459B3DCF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KML2</accession>
    <name>B1KML2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tripartite ATP-independent periplasmic transporter DctQ component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324356.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1725"/>
    <dbReference type="EnsemblBacteria" id="ACA86010">
        <property type="protein sequence ID" value="ACA86010"/>
        <property type="gene ID" value="Swoo_1725"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1725"/>
    <dbReference type="eggNOG" id="COG3090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_3_2_6"/>
    <dbReference type="OMA" id="LEWPTWI"/>
    <dbReference type="OrthoDB" id="1947990at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23918" checksum="BD53C793CB2F9114" modified="2008-04-29" version="1" precursor="true">MINRLYTHFEEGLLNLLITSMTVLVFVEVIARFFFNTGFLWIQELTLTLSAWFVLFGMSYGVKVGAHIGVDAFVTKLPKQGRKIAALMATTICIGYCLMFLKGSWDYLSKMHEIGIPMEDIDFPHLLINQLDPDFAWEALRIDIEEPAVPLWLSQSILLFGFGLLLFRFIELFIAIARNKTLGFTLADEAKESMQLAQEISSNNHKDDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMM4</accession>
    <name>B1KMM4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325738.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3131"/>
    <dbReference type="EnsemblBacteria" id="ACA87402">
        <property type="protein sequence ID" value="ACA87402"/>
        <property type="gene ID" value="Swoo_3131"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3131"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_32_6"/>
    <dbReference type="OMA" id="CDLVARW"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="202"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="328" mass="38345" checksum="9D609C5EF441F859" modified="2008-04-29" version="1">MKKKAVNEREPNNLNLSTLNIEVEEVDWHKWQRLINICAEMLNAPAMIINRVTPEGVEKFLASQTCQKQLDTNQFNMDHNKFCLNVITESQILYVKDIREDCRYQKEEMPYLSYLGLPITWPDGSIFGSLSVLDTQTTNYPDEYIDALSVIKEVIDSDLRHLYKEDQLLKMSYTDPLTQIYNRRGLIDLLQSTQDLARRLKRQLILIYFDLDKFKTANDKYGHDMGDKLLNLFAMNLKKNSRSCDLVARWGGDEFIVIIHAEDIESIKVYIDRMNQHLADQTYLPEIHFSYGYAVIKPDDSSTLAQLLSTADENMYRNKQLKRTDHKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMY3</accession>
    <name>RL3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplC</name>
        <name type="ordered locus">Swoo_4690</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Methylated by PrmB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327260.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMY3"/>
    <dbReference type="SMR" id="B1KMY3"/>
    <dbReference type="STRING" id="392500.Swoo_4690"/>
    <dbReference type="EnsemblBacteria" id="ACA88940">
        <property type="protein sequence ID" value="ACA88940"/>
        <property type="gene ID" value="Swoo_4690"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4690"/>
    <dbReference type="eggNOG" id="COG0087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044142_4_1_6"/>
    <dbReference type="OMA" id="KRMAGRY"/>
    <dbReference type="OrthoDB" id="1270636at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000141921" description="50S ribosomal protein L3">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <sequence length="212" mass="22566" checksum="5BF683D7A33D32A6" modified="2008-04-29" version="1">MAIGLIGRKVGMTRIFTEDGASIPVTVIEIAANRVTQVRTLETDGYRALQVTTGTKKANRITKPEAGHFAKAGVEAGRGLWEVRLADDEGEGIEVGAELNVDIFADVAKVDVTGQSKGKGFQGGIKRWNFHAQDMTHGNSLAHRSNGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLDVVRVDAERNLLLVKGAVPGATNGNLIIKPAVKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ4</accession>
    <name>RL11_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplK</name>
        <name type="ordered locus">Swoo_4701</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012153448.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMZ4"/>
    <dbReference type="SMR" id="B1KMZ4"/>
    <dbReference type="STRING" id="392500.Swoo_4701"/>
    <dbReference type="EnsemblBacteria" id="ACA88951">
        <property type="protein sequence ID" value="ACA88951"/>
        <property type="gene ID" value="Swoo_4701"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4701"/>
    <dbReference type="eggNOG" id="COG0080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_2_0_6"/>
    <dbReference type="OMA" id="CKQFNAK"/>
    <dbReference type="OrthoDB" id="1702697at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000195715" description="50S ribosomal protein L11">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <sequence length="142" mass="15007" checksum="FC38CC3348615B5B" modified="2008-04-29" version="1">MAKKVDGYIKLQVAAGAANPSPPVGPALGQKGVNIMEFCKAFNARTEKFEKGMPIPVVITVYSDRSFTFETKTPPASFLLLKAAGLKSGSGRPNTEKVGTIKRSAVQEIAETKAADMTGADIEAMTRSIEGTARSMGLVVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN68</accession>
    <name>B1KN68_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trmL</name>
        <name evidence="6" type="ordered locus">Swoo_0264</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322914.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0264"/>
    <dbReference type="EnsemblBacteria" id="ACA84565">
        <property type="protein sequence ID" value="ACA84565"/>
        <property type="gene ID" value="Swoo_0264"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0264"/>
    <dbReference type="eggNOG" id="COG0219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110125_1_0_6"/>
    <dbReference type="OMA" id="AGLDYWH"/>
    <dbReference type="OrthoDB" id="1578095at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00185">
        <property type="entry name" value="tRNA_yibK_trmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17453" checksum="DE55F5D009DF1EC0" modified="2008-04-29" version="1">MFHIALYEPEIAPNTGNIIRLCANNGCQLHLIEPLGFDLEEKKLRRAGLDYNDLTRVTRHKDFESFLQAMEGKRIMACTTKGSRHHTELSFEKEDVLLFGPETRGLPIEIIESLPTSQRLKIPMTPNSRSLNLSNAVAIISYEAWRQIGFEGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNA5</accession>
    <name>B1KNA5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division protein ZapD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Z ring-associated protein D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zapD</name>
        <name evidence="6" type="ordered locus">Swoo_0301</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Localizes to mid-cell in an FtsZ-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ZapD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322951.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0301"/>
    <dbReference type="EnsemblBacteria" id="ACA84602">
        <property type="protein sequence ID" value="ACA84602"/>
        <property type="gene ID" value="Swoo_0301"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0301"/>
    <dbReference type="eggNOG" id="COG4582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076303_0_0_6"/>
    <dbReference type="OMA" id="LPAYYAW"/>
    <dbReference type="OrthoDB" id="1453477at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01092">
        <property type="entry name" value="ZapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009777">
        <property type="entry name" value="ZapD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027462">
        <property type="entry name" value="ZapD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036268">
        <property type="entry name" value="ZapD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39455">
        <property type="entry name" value="PTHR39455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07072">
        <property type="entry name" value="ZapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160950">
        <property type="entry name" value="SSF160950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0717">Septation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="28678" checksum="CE4A776C077DF3C7" modified="2008-04-29" version="1">MTELTYEQPLNEKTRSFLRLEYLSQQLETNVEQDHQHRCFYPLFSLCELTERCDYRGEVLKDLDKQIITLSNWQTLPHIDKQQVEFYLNRLVTAKETLQACDRPGSALKQDRFLAALRQRFNMPGACCNFDLPQLHYWLAKPWDVRQQEYLAWVENFTALLSPIKLLLELTRQTTQFNDTTAKVGFFQGNSNQALSMIRVKIDSQQGCYPTISGHKNRFAIHFVQFEQQKHSDKTIEFQLATCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB8</accession>
    <name>B1KNB8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">General secretion pathway protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322964.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0314"/>
    <dbReference type="EnsemblBacteria" id="ACA84615">
        <property type="protein sequence ID" value="ACA84615"/>
        <property type="gene ID" value="Swoo_0314"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0314"/>
    <dbReference type="eggNOG" id="COG4969">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091705_4_5_6"/>
    <dbReference type="OMA" id="TKAQACI"/>
    <dbReference type="OrthoDB" id="2056712at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="14420" checksum="148096B4C2F0B492" modified="2008-04-29" version="1" precursor="true">MKGIQLSKKLNKQAKGFTLIELMIVVAIIGILAAVALPAYRDYTGSAHGGAAMKGLGAFTSKAVTCVQSGRACDSINGDTGQLAGSTAVTGLSATAEFAEGVGGDIAFDEGSCAVTATINPNGTVTFAAASSGTGADDAQCQDGAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNH9</accession>
    <name>B1KNH9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="7">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1772"/>
    <dbReference type="EnsemblBacteria" id="ACA86056">
        <property type="protein sequence ID" value="ACA86056"/>
        <property type="gene ID" value="Swoo_1772"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1772"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_0_4_6"/>
    <dbReference type="OMA" id="RVDGYWE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="283" mass="31316" checksum="D8FA4837B28C4B44" modified="2008-04-29" version="1">MRPDYLYLFFNIQGIVMHPMQTIAVRAARAAGQTIIRAFAELDKIEVTAKGINDYVTNVDKEAEAAITYQIRKSYPDHTIVGEENGENKGENKEFVWIIDPLDGTNNFVRGIPHFAVSIALQHKGKTEVAVVYDPIRDELFTATRGKGAKFNDFRMRVSKHNELNETIIATGFPFKAKQHTETYMKIFGELFTQCADVRRAGSAALDLAYVAAGRVDGFFEIGLKPWDIAAGDLLVREAGGTVTDFTGNHEYMNSGNIIAGAPKVTSAIVKTARPLLSEALKR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNJ0</accession>
    <name>NDK_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="1">NDK</shortName>
            <shortName evidence="1">NDP kinase</shortName>
            <ecNumber evidence="1">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ndk</name>
        <name type="ordered locus">Swoo_1783</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NDK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324413.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNJ0"/>
    <dbReference type="SMR" id="B1KNJ0"/>
    <dbReference type="STRING" id="392500.Swoo_1783"/>
    <dbReference type="EnsemblBacteria" id="ACA86067">
        <property type="protein sequence ID" value="ACA86067"/>
        <property type="gene ID" value="Swoo_1783"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1783"/>
    <dbReference type="eggNOG" id="COG0105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060216_8_1_6"/>
    <dbReference type="OMA" id="KIVAMKM"/>
    <dbReference type="OrthoDB" id="1752581at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0546">Nucleotide metabolism</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000125018" description="Nucleoside diphosphate kinase">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <sequence length="143" mass="15463" checksum="47CF6308E8BEB057" modified="2008-04-29" version="1">MAIERTFSIIKPDAVAKNNIGAIYNRFETAGLKIIASKMVHLSKEQAEGFYAEHSERPFFGALVAFMTSGPIMVQTLEGENAVLAHRDILGATNPAEAAPGTIRADFAESIDENAAHGSDSVASAEREVAYFFSAEELCPRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNK7</accession>
    <name>B1KNK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium:dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324430.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1800"/>
    <dbReference type="EnsemblBacteria" id="ACA86084">
        <property type="protein sequence ID" value="ACA86084"/>
        <property type="gene ID" value="Swoo_1800"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1800"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_1_6"/>
    <dbReference type="OMA" id="QATNTPM"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="436" mass="46249" checksum="2B50E47556BEC0FA" modified="2008-04-29" version="1">MSLTQSKKLGLTSKILIGMGAGIILGLLLRNLFPDSSFINEYITEGFLHVIGTVFVSGLKMLVVPLVFISLVCGTCSLSDPSKLGRLGGKTIAFYLFTTAIAISVAISIAILVHPGNASLVSEGLSFNAKEAPSLSEVLINIVPTNPLQAMSEGNMLQIILFAVIFGFAISHIGERGKRVAALFNDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLETFGSVVKYFFVVLGVLLIHGFIVYPSLLKLFTGLNPLIFIRKMRDVQLFAFSTASSNATLPVTIEAAEHRLGVDNKVASFTLPLGATINMDGTAIMQGVATVFIAQVYGVDLTITDYTMVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDSVATVIIAKSENEFDETTFNDTQAGKTAGSFNEQLHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL2</accession>
    <name>B1KNL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324435.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1805"/>
    <dbReference type="EnsemblBacteria" id="ACA86089">
        <property type="protein sequence ID" value="ACA86089"/>
        <property type="gene ID" value="Swoo_1805"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1805"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_6"/>
    <dbReference type="OMA" id="FLRTYMY"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08413">
        <property type="entry name" value="PBP2_CysB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037423">
        <property type="entry name" value="CysB_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="36281" checksum="C63A5266C52DF28D" modified="2008-04-29" version="1">MKLQQLRYIAEVVNHNLNVSATAENLYTSQPGISKQVRMLEDELGIQIFGRSGKHLTHVTPAGEQVISIANNILGKVESIKKVAEEYTKPDQGELNIATTDTQARYALPNIIRGFIERYPKVNLHMHQGTPSQISELAARGDADFAIATEGMHLYSDLIMLPCYHWNRSIVVKRDHPLASRSNISIEDLGRFPLVTYVFGFDRESEIEKSFNSAGLEPRVVFSATSADVLKTYVRLGLGVGVIASMAIDPVMDRDLVAIDASHLFGHSTTKIGFRKGNFLRTYMYEFIEHFAPHLTKEVVEKAVGLRDPQLIENMFANIELPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS1</accession>
    <name>B1KNS1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PGA_cap domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3259"/>
    <dbReference type="EnsemblBacteria" id="ACA87529">
        <property type="protein sequence ID" value="ACA87529"/>
        <property type="gene ID" value="Swoo_3259"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3259"/>
    <dbReference type="eggNOG" id="COG2843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_387688_0_0_6"/>
    <dbReference type="OMA" id="FGGDVMM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07381">
        <property type="entry name" value="MPP_CapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGA_cap" evidence="2">
        <location>
            <begin position="128"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="710" mass="79483" checksum="BCCFBCCDB97C4E7F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS2</accession>
    <name>B1KNS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325866.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87530">
        <property type="protein sequence ID" value="ACA87530"/>
        <property type="gene ID" value="Swoo_3260"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3260"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042893_0_0_6"/>
    <dbReference type="OMA" id="QVYRADS"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="7"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="43"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="375" mass="41693" checksum="DAE970FE50D1D9F8" modified="2008-04-29" version="1">MPEKTALVLGGGGARAAYQIGVLKAIVQFYPRNHGIPFKIICGTSAGAINGTSIATHASCFHLGVRKLEWVWRNFRTDKIYSASMSGVLKHLGKMLLMSMQDDKVNTNAGSLFNSEPLRGLLNELINFARIDRNIGSGALSALSIDTSCYNSARSVTFFQGNHDIAQWHRDRRSGQRTQLNTDHLLASSAIPLVFPSVKLNQGYYGDGSVHQLAPLSSPIHLGAKKLFVINLESPHKQQSQELEHHPKTATIAGHLLDTIFSDTLNSDLERLERINNTLSLIPEEDTKKLPLTQIQTLVIKPSEDLSKLASRYYNEMPFAVKSMLRPIGINQQTDSSIVSYLLFEKSYCSALIDLGYQDAMCQIDEIRDFFEIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNV0</accession>
    <name>B1KNV0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flavodoxin/nitric oxide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325894.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3288"/>
    <dbReference type="EnsemblBacteria" id="ACA87558">
        <property type="protein sequence ID" value="ACA87558"/>
        <property type="gene ID" value="Swoo_3288"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3288"/>
    <dbReference type="eggNOG" id="COG0369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051402_4_1_6"/>
    <dbReference type="OMA" id="SYDHFCG"/>
    <dbReference type="OrthoDB" id="1961680at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="5">
        <location>
            <begin position="4"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="17201" checksum="92D68F14B0480EC3" modified="2008-04-29" version="1">MRKVNLIFGTVYGNAQFVAETLRDDLQKLGREVQLFQSDELSSFIPPQDETLLIVSSTTGQGDVPDEILPWFEMLKSQAPYLPNLRYGVVALGDSSYDTFCQAGIQFDELLTELGAHRIGRLLKIDACETMEPEVSAKAWLQIWNTQIDIETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP38</accession>
    <name>B1KP38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA binding domain protein, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327386.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4820"/>
    <dbReference type="EnsemblBacteria" id="ACA89069">
        <property type="protein sequence ID" value="ACA89069"/>
        <property type="gene ID" value="Swoo_4820"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4820"/>
    <dbReference type="eggNOG" id="COG1910">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053344_1_0_6"/>
    <dbReference type="OMA" id="GIYFRRQ"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12727">
        <property type="entry name" value="PBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="2">
        <location>
            <begin position="9"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="1">
        <location>
            <begin position="95"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="33984" checksum="69C93A2C1234A66C" modified="2008-04-29" version="1">MTEPSELIYMSAKQVAEYLDLNEKKVYSMANDRVLPATKITGKWLFPKILIDRWIMDSCHSGMLSDRMHITGSDDPLLSMLVSRLMTQIGKSDLVSYSSTGSRMGLDLLSRGYADVCTLHWGSVDERNVRHPALLKSYPNHQQWVMVHGYTRKQGLMVRNNMLQQCQEEDKIVSLPWRWVARQTGAGSQQHLEHWLMKQGAALSHLNANVTAYSERELAAYVARGDADIGFGCQSVAMESGLGFIPLVTESFDFVMPQGIYFRRQLQHLFDMLGSTQTRQLAATLGGYDLTDCGQLLWNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP45</accession>
    <name>B1KP45_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M6 family metalloprotease domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327393.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4827"/>
    <dbReference type="EnsemblBacteria" id="ACA89076">
        <property type="protein sequence ID" value="ACA89076"/>
        <property type="gene ID" value="Swoo_4827"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4827"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010858_1_0_6"/>
    <dbReference type="OMA" id="WAHRWYA"/>
    <dbReference type="OrthoDB" id="461923at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020008">
        <property type="entry name" value="GlyGly_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008757">
        <property type="entry name" value="Peptidase_M6-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05547">
        <property type="entry name" value="Peptidase_M6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00801">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03501">
        <property type="entry name" value="GlyGly_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03296">
        <property type="entry name" value="M6dom_TIGR03296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="779"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="845"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="965" mass="102839" checksum="281B5BC03DF1B311" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP84</accession>
    <name>B1KP84_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmI</name>
        <name evidence="8" type="ordered locus">Swoo_0353</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323003.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0353"/>
    <dbReference type="EnsemblBacteria" id="ACA84654">
        <property type="protein sequence ID" value="ACA84654"/>
        <property type="gene ID" value="Swoo_0353"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0353"/>
    <dbReference type="eggNOG" id="COG0313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044779_1_0_6"/>
    <dbReference type="OMA" id="RTMVFFE"/>
    <dbReference type="OrthoDB" id="1059309at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="280" mass="30680" checksum="6F0AB4B1BAC5EFFB" modified="2008-04-29" version="1">MDLAAALYIVPTPIGNLGDISSRAIDVLNNVKLIACEDTRHSGILLSHFGIETRKTALHDHNERDRAEWIIQKLSNGEAIALISDAGTPLISDPGYHLVSQVRAAGYKVIPLPGACAAITALSASGLPSDRFSFEGFLPSKEKGRLDKLTELKEDPRTLIFYESPHRIVHSLESILTALGEDRIIAMAREVTKTFETFLYGTVKEVLEQVKSDPNQQKGEIVLMCHGYRLVEDEGIPAVVINTLKLLCEELPLKKASALAGQIHGMKKNALYKYGLENGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPG2</accession>
    <name>B1KPG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324461.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1831"/>
    <dbReference type="EnsemblBacteria" id="ACA86115">
        <property type="protein sequence ID" value="ACA86115"/>
        <property type="gene ID" value="Swoo_1831"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1831"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087351_0_1_6"/>
    <dbReference type="OMA" id="FYETVHT"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="18115" checksum="C418C9E63C9D4523" modified="2008-04-29" version="1">MIKVRAFNAQSSSSDIDELWTLKFNTIRKVNCRDYTQAQVKAWAPDSFDRESWLKRVSEMDPLIAEVDGVVVGFADLQVDGYIDHFFCHLDYQGRGVGKTLMKALMEKGARLGVPRYYSHVSITARPFFEHFGFTLVKQQSVEVRGEVLTNYVLEKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPG3</accession>
    <name>B1KPG3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1832</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324462.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1832"/>
    <dbReference type="EnsemblBacteria" id="ACA86116">
        <property type="protein sequence ID" value="ACA86116"/>
        <property type="gene ID" value="Swoo_1832"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1832"/>
    <dbReference type="eggNOG" id="COG0372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025068_0_0_6"/>
    <dbReference type="OMA" id="TVGWCAQ"/>
    <dbReference type="OrthoDB" id="1412360at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06114">
        <property type="entry name" value="EcCS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="430" mass="48153" checksum="CD417F66DD190B8D" modified="2008-04-29" version="1">MADKIAKLELPGNESIELPVKEGTAGFDVIDISKLGSKGHFTFDPGFLATASCESAITYIDGDQGILLHRGYPISELAVESDYLDLCYLLLYGELPTKTQYEKFVHTVKNHTMVNEQLAAFFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDERHREIAAFRLVSKMPTIAAMCYKYSIGQPFVYPRNELSYAGNFLSMMFGVPCEEYQVNPIVERAMDRIFILHADHEQNASTSTVRLAGSSGANPFACIAAGIASLWGPAHGGANEACLNMLEEIGTVDRIPEFIARAKDKEDPFRLMGFGHRVYKNFDPRAKVMRETCHEVLGELKVDDPLLDVAMELERIALEDEYFVSKKLYPNVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEMLDQPGHKISRPRQLYTGDEERTFIPQGKREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPI1</accession>
    <name>B1KPI1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324480.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1850"/>
    <dbReference type="EnsemblBacteria" id="ACA86134">
        <property type="protein sequence ID" value="ACA86134"/>
        <property type="gene ID" value="Swoo_1850"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1850"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087351_4_1_6"/>
    <dbReference type="OMA" id="INKGCAG"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="17531" checksum="0848CD9FB35EA44F" modified="2008-04-29" version="1">MINIRAATIADTCNIWALRTKAISQACLSHYPKEVVKQWAASPMPSNFAEILISLHAIVAEDIGENKQSTLLGFGFIDKEQGRLESLFVDPKTSRKGVGKLIATALISSAQQANLTQLQLSSTLNAVAFYQSLGFDILEKTHWQHPSGFGLASVSMSKQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM3</accession>
    <name>B1KPM3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324522.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1892"/>
    <dbReference type="EnsemblBacteria" id="ACA86176">
        <property type="protein sequence ID" value="ACA86176"/>
        <property type="gene ID" value="Swoo_1892"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1892"/>
    <dbReference type="eggNOG" id="COG0426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066633_0_0_6"/>
    <dbReference type="OMA" id="HASGNFH"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045761">
        <property type="entry name" value="ODP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19583">
        <property type="entry name" value="ODP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="29"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="28190" checksum="6DDF940260CECFFD" modified="2008-04-29" version="1">MKSQLLVEAPTHKWIYFGRDPDKPEKIIDTNQYMLVTEHKALLMDPGGVELFAPMLANIVKHIPLEQLTHLFASHQDPDIISSLGLWDQTLPEAKLYSPWIWEGFIRHFGMSNITYEALPDEGSRLILDQAEVQFIPAHYLHASGNFHVYDPATRVLMSGDVGAALEGPNVSIFVDDFESHIKKMSFFHQRWMPSNAAKNDWIARVRKLDIEYMCPQHGRIFKGEQVGQFLDWFEQLEVGQAISNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW4</accession>
    <name>B1KPW4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325982.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3378"/>
    <dbReference type="EnsemblBacteria" id="ACA87647">
        <property type="protein sequence ID" value="ACA87647"/>
        <property type="gene ID" value="Swoo_3378"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3378"/>
    <dbReference type="eggNOG" id="ENOG5032RCX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073322_0_0_6"/>
    <dbReference type="OrthoDB" id="1670282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="33488" checksum="6AEA622586935EA2" modified="2008-04-29" version="1" precursor="true">MKPETQAILTTQMGKTLQSLSLVVGLTMAAGQVSATERDADGFSVDKVNSSIGRELSSAELTTVNSGRIGSLAELDQTQLNQLRFNAENNQSTGIKPKTRQEMISAHKKGLIPVKYQLKKVKGDSQANVPAAFANPIYNEFAIYDASSRLFEDNDYDGFYQTFSVTFDADVYGAYQNEHAEVYAEMYLSRNGGPWEHYYTTDIFTIVGDSTEDDFEVLTTLNSGYSADYYDVLIDLYEVGYTDIVATVSSDDFDSLYALPLESSDRDYIDNGNSSSEGHGGGSLSFIVLLGLALLARLRGLSTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPX5</accession>
    <name>B1KPX5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325993.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87658">
        <property type="protein sequence ID" value="ACA87658"/>
        <property type="gene ID" value="Swoo_3390"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3390"/>
    <dbReference type="eggNOG" id="ENOG5031I83">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1757580_0_0_6"/>
    <dbReference type="OMA" id="GTCTQGD"/>
    <dbReference type="OrthoDB" id="1975973at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="16517" checksum="4D422F892850ADD6" modified="2008-04-29" version="1">MLVIKNEKMLSLVLVIVYGLLVCLGAVAGTCTQGDDARFYASLLYGTPLFLLLILRVAFDKNRILFKRINVVAALLLMTSVSYFWMPLMIDTTIKGHHLCGGDFDSYINGSYALERFIPVLHIFSSLFVLIFTVSKLMAAKRSKLANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ50</accession>
    <name>B1KQ50_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327479.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4914"/>
    <dbReference type="EnsemblBacteria" id="ACA89163">
        <property type="protein sequence ID" value="ACA89163"/>
        <property type="gene ID" value="Swoo_4914"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4914"/>
    <dbReference type="eggNOG" id="COG3214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043035_0_1_6"/>
    <dbReference type="OMA" id="FEYWAHE"/>
    <dbReference type="OrthoDB" id="1594634at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="45679" checksum="31A6B933CBFF3853" modified="2008-04-29" version="1">MSSPYSANEWLQLNLQQQGLLTPADSVSKAVEQLSYVQIDSINVVERAHHHVLFNRISDYQTSMLDSAMAKSEIFEYWSHAAAYLPIEDFRFSLWQKQQLKQGGKHWFEPEHKVMREVKAKIAAEGPLKASHFTNTSKAATTGWWDWKPAKRALEQLFMHGDLMVAQRDKFQKVYDLTERILPSHIDMQLPDDTEFARYLIYRYLTAHGFGTVQQMVYLRKKIKPSLVKTLNELCLAGEVARFTESGLEYFYLPHQQLLTSLPDRVWLLNPFDNLVIQRQRLNQLFDFNYQIEVYVPAAKRQFGYYSLPILWRDRFIGRVDVKAERKQGVLLLQKLTIEEGAFSTSATSSELEEFIAAFRLAVDEYAAFNKCDEWELVETNLFNDLLINKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA0</accession>
    <name>B1KQA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323104.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0457"/>
    <dbReference type="EnsemblBacteria" id="ACA84755">
        <property type="protein sequence ID" value="ACA84755"/>
        <property type="gene ID" value="Swoo_0457"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0457"/>
    <dbReference type="eggNOG" id="COG2013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040551_4_1_6"/>
    <dbReference type="OMA" id="FQPGAYI"/>
    <dbReference type="OrthoDB" id="1063432at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="23867" checksum="AADDA88A2A591C8D" modified="2008-04-29" version="1">MEAKIMGSQAFSYIDIDLEPGETVIAESDAMSSMDADLDLTATFNGGFFKGLLKKFFGGETLFISRYSNNTSAPKRVTLVQPVPGELRCHELNGDEFNLQPGAYLASTEGVKLGLRWAGFVSFIAREGLFKLTVTGEGKVWYGAYGALLEKEIDGEYIVDTSHLVAYEPGIKLKLQLAGGIFSSFFGGEGLVTRVEGKGKIIVQSRSVSGLAGWLNPKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ1</accession>
    <name>B1KQZ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3481</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326081.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3481"/>
    <dbReference type="EnsemblBacteria" id="ACA87747">
        <property type="protein sequence ID" value="ACA87747"/>
        <property type="gene ID" value="Swoo_3481"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3481"/>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_747805_0_0_6"/>
    <dbReference type="OMA" id="YAPKFVD"/>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767576" evidence="9">
        <location>
            <begin position="31"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="284"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="363" mass="40259" checksum="26E03BE6FB39CF24" modified="2008-04-29" version="1" precursor="true">MQFESGLRKSLFAATLSLALCSATSFTVSASEFSDSYAAYQSAVSDKNYSDAQVYADKAYQLGKEIYPKGSLDLANLALNLGSALEINEKQTQAFDAYSQALAIYQTHFDDDAIELIEPLIGAAGTAEKPKVARKYFIQAIDIAEDADDPILLANTLMSAFNKLSKTPLYSRKIQNYAIKAFEIYEDELPEDAMARVRATYIVGMIRKSKKQDAKAIELLNKVVKQFSVLDYSHPYELASHAQLVELYEKKGLSEKSTQHCIAIGSMRPWLDTQEQVPLYRLPPKYPVNSARAGREGMVQLSFIVDESGFVTEPKVIMSEGGSGFEKESLKAIKHWRYAPKFVDGKPVAAPSTVQLDYTMAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR01</accession>
    <name>B1KR01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323166.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0521"/>
    <dbReference type="EnsemblBacteria" id="ACA84818">
        <property type="protein sequence ID" value="ACA84818"/>
        <property type="gene ID" value="Swoo_0521"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0521"/>
    <dbReference type="eggNOG" id="ENOG5033267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118094_0_0_6"/>
    <dbReference type="OMA" id="RLICYDN"/>
    <dbReference type="OrthoDB" id="1751290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016987">
        <property type="entry name" value="UCP023238"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032038">
        <property type="entry name" value="UCP023238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764769" evidence="1">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="17445" checksum="161FE4728434FE3F" modified="2008-04-29" version="1" precursor="true">MRLRWITAVAILVSANATAGIEQQLSACAANTDKLDRLICYDALAQKVKTKGPATPPVAGAATVAAVPVTLPANIEDEFGNLKKEKADAIEKIYLEVASIKKDPYGALKLSFTNGQVWKQTDGRRFKVKVNQSVFIEKAALGSFILGSDDRNSTIRVKRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR17</accession>
    <name>B1KR17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0538</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323182.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0538"/>
    <dbReference type="EnsemblBacteria" id="ACA84834">
        <property type="protein sequence ID" value="ACA84834"/>
        <property type="gene ID" value="Swoo_0538"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0538"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010403_0_0_6"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="838"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1055" mass="120371" checksum="6F8860D7F1CB191F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR28</accession>
    <name>B1KR28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323193.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0549"/>
    <dbReference type="EnsemblBacteria" id="ACA84845">
        <property type="protein sequence ID" value="ACA84845"/>
        <property type="gene ID" value="Swoo_0549"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0549"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131496_6_3_6"/>
    <dbReference type="OMA" id="YEEWIDD"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="11163" checksum="A8198F0699F565E8" modified="2008-04-29" version="1">MNEHTFIFAKITPKPKYFEVSKEAIMNIISQTRNEPGCLEFTLHEDGSGNLCLYEEWIDDNALKLHHEMDYTKAVFEAYTDWLAIPPEISKLIKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR34</accession>
    <name>B1KR34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323199.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0555"/>
    <dbReference type="EnsemblBacteria" id="ACA84851">
        <property type="protein sequence ID" value="ACA84851"/>
        <property type="gene ID" value="Swoo_0555"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0555"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_13_0_6"/>
    <dbReference type="OMA" id="DESHLWV"/>
    <dbReference type="OrthoDB" id="1174564at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="131"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="46216" checksum="BB53E874431A9B18" modified="2008-04-29" version="1" precursor="true">MKHNTDLKIIEVNAITKAIAKAMFSAKRFGLFITLAAAISIPTTALAGDGHEHASIESGSGEPHVEQIAHQNEESHDHDGESKVVADDGHGHGAGEAEEESHALVLSDEQLALANIQVEKLAVATFSLEAVATATLVVDRDKTMTLAPQLDVRVEQRHVVPGQEVTQGQALLTLGGVAVAQAQADYINAAAEWSRVSRMSKSAVSASRRLQAQVDAELKRAILEAMKMTSKQIAQLESNPSNIGSYQLLAPINGRVQQDLAKLGQIVPAGTALMQLTDESHLWVEAQVTPAQSEKVSIGSVALVRVGERSLEAKVIGRSHELDSVTRTEQILVSLENPGHVIHAGQFAELYLPDSIETGFVLPDAALTRGGDGDWQVFIQDEDGFEAVEVDVVESQRGMNLVRGLAVGSQVVVSGAFFLASELAKSGFDIHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR37</accession>
    <name>B1KR37_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323202.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0558"/>
    <dbReference type="EnsemblBacteria" id="ACA84854">
        <property type="protein sequence ID" value="ACA84854"/>
        <property type="gene ID" value="Swoo_0558"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0558"/>
    <dbReference type="eggNOG" id="ENOG5032S9M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2541662_0_0_6"/>
    <dbReference type="OMA" id="TENPMMA"/>
    <dbReference type="OrthoDB" id="1890270at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021376">
        <property type="entry name" value="DUF2999"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11212">
        <property type="entry name" value="DUF2999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9135" checksum="821FC8F7174A1636" modified="2008-04-29" version="1">MNPILAILKEHNVSDAQINQLFQAMTDNPMMAMGMIGQLGIQPEKLQQLMALVMQNPALIKEAVDELGLDFSKVEAAKAQLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR75</accession>
    <name>B1KR75_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0596</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323240.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0596"/>
    <dbReference type="EnsemblBacteria" id="ACA84892">
        <property type="protein sequence ID" value="ACA84892"/>
        <property type="gene ID" value="Swoo_0596"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0596"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027270_1_0_6"/>
    <dbReference type="OMA" id="KILMLTH"/>
    <dbReference type="OrthoDB" id="137860at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="707" mass="81683" checksum="082BD64BEF844645" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR76</accession>
    <name>B1KR76_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0597"/>
    <dbReference type="EnsemblBacteria" id="ACA84893">
        <property type="protein sequence ID" value="ACA84893"/>
        <property type="gene ID" value="Swoo_0597"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0597"/>
    <dbReference type="eggNOG" id="COG3593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023912_0_0_6"/>
    <dbReference type="OMA" id="MQEVFIR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01026">
        <property type="entry name" value="TOPRIM_OLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034139">
        <property type="entry name" value="TOPRIM_OLD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="773" mass="86823" checksum="D514A05DB65E3588" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRC4</accession>
    <name>B1KRC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">6-phosphogluconate dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324677.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2047"/>
    <dbReference type="EnsemblBacteria" id="ACA86331">
        <property type="protein sequence ID" value="ACA86331"/>
        <property type="gene ID" value="Swoo_2047"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2047"/>
    <dbReference type="eggNOG" id="COG2084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_1_0_6"/>
    <dbReference type="OMA" id="IFVDHTT"/>
    <dbReference type="OrthoDB" id="1194694at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="4">
        <location>
            <begin position="166"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="291" mass="31058" checksum="0B7181AC974CB5F3" modified="2008-04-29" version="1">MAKVAFIGLGVMGYPMAGHLVRHGHQVTVYNRTQTRADAWKAEFGGSVELTPCEAAKGQEFVFVCVGNDDDLRQVTLGETGVLNGMSAGSVLVDHTTASADVAREIGALASAKEIGFLDAPVSGGQAGAENGVLTVMTGGNESHFGQAKPIIEAYARCVELLGEVGAGQLTKMVNQICIAGVVQGLSEGLHFARSAGLDGEKVVEVISKGAAQSWQMENRYQTMWQGEYNLGFAVDWMRKDLNIALNEARKNGSHLPLTALVDQFYSEVQAIGGNRWDTSSLLAKLEKNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRI3</accession>
    <name>B1KRI3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2106"/>
    <dbReference type="EnsemblBacteria" id="ACA86390">
        <property type="protein sequence ID" value="ACA86390"/>
        <property type="gene ID" value="Swoo_2106"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2106"/>
    <dbReference type="HOGENOM" id="CLU_162058_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="13405" checksum="BF9327F8811DEAA0" modified="2008-04-29" version="1">MQVQANYFGSSQAQVSGVSGANGSSQVKPNSAIDAAEQIERVKQGQGLEKALIDANSASKDIHDTQGGVQLFEQTTPEQLSNRLGAKLEYERAIQGSEGAVAHYLANEHAAAREEIQQMVGIDTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRI6</accession>
    <name>B1KRI6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324738.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="ESTHER" id="9gamm-a0jb25">
        <property type="family name" value="AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86393">
        <property type="protein sequence ID" value="ACA86393"/>
        <property type="gene ID" value="Swoo_2109"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2109"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_8_2_6"/>
    <dbReference type="OMA" id="LFEFHEV"/>
    <dbReference type="OrthoDB" id="1498437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="31"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="294" mass="33085" checksum="1E108458F60DCC00" modified="2008-04-29" version="1">MSQSCAPDNEVEFQLPHIRLSGRLWGAPDKPLLLALHGWLDNANSFTPLAEQLTDYQILAIDWPGHGGSEHRPGLYPLHWIDYLYDLELLMDHLSEEQQPVAIIGHSLGGIVASAYVAAFPERVGKLVLIEAISPLYEFASKNNQRLRNSFRDHALYLKKKHKAPAVYESIEPAVKARVRLTGLDAKWCRLLVERNMHPSEAPLAVGFSWRSDPRLKLDSPLRLTFEQVDALMTEHSGNTLLITGTRGFSQINKMLVKAEAWFDQLICVELDGDHHLHMENAQGVGSQITQFLS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRJ1</accession>
    <name>MINC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable septum site-determining protein MinC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">minC</name>
        <name type="ordered locus">Swoo_2114</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with MinD and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MinC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324743.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRJ1"/>
    <dbReference type="SMR" id="B1KRJ1"/>
    <dbReference type="STRING" id="392500.Swoo_2114"/>
    <dbReference type="EnsemblBacteria" id="ACA86398">
        <property type="protein sequence ID" value="ACA86398"/>
        <property type="gene ID" value="Swoo_2114"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2114"/>
    <dbReference type="eggNOG" id="COG0850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067812_0_1_6"/>
    <dbReference type="OMA" id="RRDPLWG"/>
    <dbReference type="OrthoDB" id="1665744at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051302">
        <property type="term" value="P:regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901891">
        <property type="term" value="P:regulation of cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00267">
        <property type="entry name" value="MinC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007874">
        <property type="entry name" value="MinC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="PTHR34108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05209">
        <property type="entry name" value="MinC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="SSF63848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01222">
        <property type="entry name" value="minC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0717">Septation</keyword>
    <feature type="chain" id="PRO_1000114295" description="Probable septum site-determining protein MinC">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00267"/>
        </source>
    </evidence>
    <sequence length="221" mass="23562" checksum="2793B40968D21464" modified="2008-04-29" version="1">MQTPSLELKGSSFTLSVLHINQLDLEKVTIELDGKLAIAPQFFLGAPLVVNLSRIKAPDYNLAALKDLLISRQLVIVGITEAIDEIATQAKALGLANIKSGKQSNTQPQLPKTSKIVKQNVRSGQQIYAKNADLVIFGTVGNGAEVIADGSIHIYGNLRGKAMAGASGDKHAIIIARSLEAELVSIAGQYWLAENIQHNSTTKSGCVRLEGESLTIEALPL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD54</accession>
    <name>RLMG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase G</fullName>
            <ecNumber evidence="1">2.1.1.174</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m2G1835 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (guanine-N(2)-)-methyltransferase RlmG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmG</name>
        <name type="ordered locus">Swoo_3625</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(1835) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10218"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.174"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RlmG family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.174" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326222.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KD54"/>
    <dbReference type="SMR" id="B1KD54"/>
    <dbReference type="STRING" id="392500.Swoo_3625"/>
    <dbReference type="PRIDE" id="B1KD54"/>
    <dbReference type="EnsemblBacteria" id="ACA87889">
        <property type="protein sequence ID" value="ACA87889"/>
        <property type="gene ID" value="Swoo_3625"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3625"/>
    <dbReference type="eggNOG" id="COG2813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040288_4_0_6"/>
    <dbReference type="OMA" id="DFLAWRM"/>
    <dbReference type="OrthoDB" id="1027015at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052916">
        <property type="term" value="F:23S rRNA (guanine(1835)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01859">
        <property type="entry name" value="23SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017237">
        <property type="entry name" value="rRNA_m2G-MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47816:SF5">
        <property type="entry name" value="PTHR47816:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037565">
        <property type="entry name" value="RRNA_m2G_Mtase_RsmD_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000366520" description="Ribosomal RNA large subunit methyltransferase G">
        <location>
            <begin position="1"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="419" mass="46575" checksum="4FAC427C318A57A7" modified="2008-04-29" version="1">MTTQFSVAGIELELARYPKDQESNLQAWDAADEHLIKHLIETEQTPVVTAIINDNFGALTACLRSIAPTWPLMVETDAKTSLLGNLQNLATNNLSSEGIEWLNSREALPEQIELVLMKLPKNLTYFAHQLNRLSQVLPKGTQVLISAKAKSINKSVLELIGKNLGSASASLTWKKTRVITCISDGEIRSLPKEMQWSVPRLNLEIRNLSNVFAANKLDIGAEIMLENMPKGDFKSIIDLGCGNGILGLHAKQLFPQAYIHFVDDSEMAIESAKQNWALNKLDTQGLVGEQATFGWDDCLTHMSEGVRPDLVLCNPPFHQGEAITDHIAWQMFLQSWRALKNGGILHVVGNRHLAYHIKLQRIFKNCTTVASNGKFVILQAQKISKKAEPFETHPTEAEAKVEVTESKPHPQSSLYGTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD88</accession>
    <name>B1KD88_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3661</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326256.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3661"/>
    <dbReference type="EnsemblBacteria" id="ACA87923">
        <property type="protein sequence ID" value="ACA87923"/>
        <property type="gene ID" value="Swoo_3661"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3661"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_10_4_6"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764301" evidence="4">
        <location>
            <begin position="25"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="34"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="500" mass="55674" checksum="75720DD3CF780344" modified="2008-04-29" version="1" precursor="true">MKCRCTTLSVAVLCSIMVTSCSQSNIEPKVNRQPNVIYFLADDLGVGDLGSYGQQHIRTPNIDKLAAEGMRFSRHYAGSSVCAPSRASLMTGRDMGHTDIRGNIQLMDQPDSPEYQGQYPLAQGTITLAHLFQLAGYQTGAFGKWGLGSLQSSGNPKAMGFDQFYGYLDQRHAHNYFPQYLWDGDEVARLDNPAINVHPKLDRDKSDHREYMGKDYAPYKILARAKEFISQNRDEAFFLYVPFVVPHAAIQIPDKELDGYQFDETAHRLGEPRAYTPHPKPRAARAAMISRMDRDVGDIMAMLKELGLDDNTLVLFSSDNGATAAGGSDINFFNSTAGARGEKATLYEGGIRAPLIARWPGNISAGSESDHLSAFWDMLPTFAQLLDLSVPEGIQGISMLPTLLGKPQNQQHESLYWEFFSRNPSQAVVMGNWKAIRHYSKERGKGALELGATALYNLQEDPSESQNLAAKHPELVKKAEMIMAQRQRSPHLPWNFQSYN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDW3</accession>
    <name>NADD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="1">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nadD</name>
        <name type="ordered locus">Swoo_3705</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NadD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326297.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDW3"/>
    <dbReference type="SMR" id="B1KDW3"/>
    <dbReference type="STRING" id="392500.Swoo_3705"/>
    <dbReference type="EnsemblBacteria" id="ACA87965">
        <property type="protein sequence ID" value="ACA87965"/>
        <property type="gene ID" value="Swoo_3705"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3705"/>
    <dbReference type="eggNOG" id="COG1057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069765_0_0_6"/>
    <dbReference type="OMA" id="IHIGHLI"/>
    <dbReference type="OrthoDB" id="1433958at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000100794" description="Probable nicotinate-nucleotide adenylyltransferase">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <sequence length="209" mass="23788" checksum="6A28DAEAC7D323D5" modified="2008-04-29" version="1">MRIGILGGTFDPIHFGHIRPAQEVKQTLNLDKVWLMPNHIPPHKTSTSVSTEQRLEMTQLVCDEYSEFELCAIEAKREAPSYLVTTLKQITNSHPNDEFFFIMGMDSLLSLDTWFEWQSLFGLCHIVVCQRPGWSLSPDSSIFSQYQSRVRSPNKITGKQSGLIIPIPVTPQAISSTHIREQLSEGITPTNALPDKIIQYIEDKNLYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE09</accession>
    <name>B1KE09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP dicarboxylate transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326343.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3752"/>
    <dbReference type="EnsemblBacteria" id="ACA88011">
        <property type="protein sequence ID" value="ACA88011"/>
        <property type="gene ID" value="Swoo_3752"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3752"/>
    <dbReference type="eggNOG" id="COG4664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019824_4_0_6"/>
    <dbReference type="OMA" id="FRIQSYM"/>
    <dbReference type="OrthoDB" id="941328at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="7"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="431" mass="46080" checksum="C8C0CE97B2B13986" modified="2008-04-29" version="1" precursor="true">MTGLALFIIAMIAIFFGFPIAFTFAGVSMAIGILVLGIDLFAFMPFRIMSTMQNTILMAVPLFIFMGIVLQKTNLAEELLESMGKLFGGLKGGLAISTIIVGLFLAASTGVVGASVVAMGVISLPVMLKHRYDPKLATGIICAAGTLGQIVPPSIILIILGDVMGLPVGDLFTAALLPSLILVSAYLIYILAIVNIKPSIAPPIKNELDEPNLTMVIKCLKLIIPPLFLIVAVLGSIYSGLATPTESSALGGVGALLLALIYSKFKFKLLFDSALETVKVSSMVFAVLIGATAFSMVFSYSGGESIVEEFFVSLPNAQWTFVLIAMLTIFILGFFIDFIEIAFIIVPILTPIALSLGLNMNWLAILIAMNLQTSFLTPPFGFSLFYLKGVAPPQIKTLAIYKGVLPFIAIQMLILALLVFFPELFGLSRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE57</accession>
    <name>B1KE57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0748</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323390.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0748"/>
    <dbReference type="EnsemblBacteria" id="ACA85043">
        <property type="protein sequence ID" value="ACA85043"/>
        <property type="gene ID" value="Swoo_0748"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0748"/>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005379_4_3_6"/>
    <dbReference type="OMA" id="MESGRIQ"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="24"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="572" mass="63926" checksum="EBFE8182005A96E1" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE71</accession>
    <name>B1KE71_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">K(+)/H(+) antiporter NhaP2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Potassium/proton antiporter NhaP2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nhaP2</name>
        <name evidence="9" type="ordered locus">Swoo_0762</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H(+)(out) + K(+)(in) = H(+)(in) + K(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29467"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323404.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0762"/>
    <dbReference type="EnsemblBacteria" id="ACA85057">
        <property type="protein sequence ID" value="ACA85057"/>
        <property type="gene ID" value="Swoo_0762"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0762"/>
    <dbReference type="eggNOG" id="COG3263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_9_2_6"/>
    <dbReference type="OMA" id="QIGMFVL"/>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006884">
        <property type="term" value="P:cell volume homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01075">
        <property type="entry name" value="NhaP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030151">
        <property type="entry name" value="NhaP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023729">
        <property type="entry name" value="NhaP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32507:SF7">
        <property type="entry name" value="PTHR32507:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="2 7" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="8">
        <location>
            <begin position="405"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="576" mass="61688" checksum="0AA6F44BFC318A58" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA7</accession>
    <name>B1KEA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0798</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0798"/>
    <dbReference type="EnsemblBacteria" id="ACA85093">
        <property type="protein sequence ID" value="ACA85093"/>
        <property type="gene ID" value="Swoo_0798"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0798"/>
    <dbReference type="eggNOG" id="COG3614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_59_6"/>
    <dbReference type="OMA" id="MLVYHPV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="5">
        <location>
            <begin position="74"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="394"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="550" mass="61862" checksum="15277F113DC0E91D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KED8</accession>
    <name>B1KED8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324860.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2235"/>
    <dbReference type="EnsemblBacteria" id="ACA86516">
        <property type="protein sequence ID" value="ACA86516"/>
        <property type="gene ID" value="Swoo_2235"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2235"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_3_6"/>
    <dbReference type="OMA" id="CVMRQGH"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="314" mass="35796" checksum="7AE5A48EBA1C4B23" modified="2008-04-29" version="1">MNISRVDLNLLVYFDVLLRELNVTRAADQLGISQPAMSNGLKRLRVLFDDPLLIRTSKGMTPTERASELKPVIRELLVGLEKAVEPKAKFNPRESEQVFRMMASDYAEATLIPLLIARLRNEAPKVILDIMTPSDVNFPDVEQGRVDMVINRFDSIPLSFHQKVLWKDSFSCLINRNHDVLKNFNLENYLNAHHVWVSKTGMGIGVGMDPDDVQRLGWVDEALAKIGAKRRITVFTRHYQAASSLAERQDLIATVPSKMARLQQDNSRVSIIPPPFDIPPIELTMAWSPLLQHNPAHKWMRELITETARIIDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF9</accession>
    <name>B1KEF9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PBPb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324880.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2256"/>
    <dbReference type="EnsemblBacteria" id="ACA86537">
        <property type="protein sequence ID" value="ACA86537"/>
        <property type="gene ID" value="Swoo_2256"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2256"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080720_0_0_6"/>
    <dbReference type="OMA" id="DVMLHVP"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766990" description="PBPb domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="5">
        <location>
            <begin position="36"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="34289" checksum="F152CC9F3B749D63" modified="2008-04-29" version="1" precursor="true">MKRINSLALGLCLLTCVLTAPSLVARSFDDIIESQYITVAVYRDFAPFSYQIDDAAYGIDIDLAHQIAKELGLELRLRWMTADENVEDDLRNNLWKGHFLKRSVADLMLRVPYDKAYSLMRDDIGELVHEQVHMFAPYHTESWQIIYNSTQIESVSTIAVFQYHDIGVEVDSIPQFYLTSAFGGRMRERAKHFSSIPLAIDAMRQGEVDAAMGLRSQISHFQQEIDTTKYPLAQNAFPMMGRQQWDIGMAIKSQYRQLGYAIGDIVESMIKQGEMEKIFSKYHAIYQTPELYLPAKTHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEH5</accession>
    <name>B1KEH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324896.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2272"/>
    <dbReference type="EnsemblBacteria" id="ACA86553">
        <property type="protein sequence ID" value="ACA86553"/>
        <property type="gene ID" value="Swoo_2272"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2272"/>
    <dbReference type="eggNOG" id="ENOG503308N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2737810_0_0_6"/>
    <dbReference type="OMA" id="FGRYIVW"/>
    <dbReference type="OrthoDB" id="2031657at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021249">
        <property type="entry name" value="DUF2788"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10981">
        <property type="entry name" value="DUF2788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="73" mass="8149" checksum="BB8BB3BA1A673110" modified="2008-04-29" version="1">MLSQYMEQIEALGLNLFFAAIFFFIGMAIRDVLKQGNVPKFGRNIVWLVLFLGCAGFIAKGLIQMFWEGSGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEL5</accession>
    <name>B1KEL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326362.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88030">
        <property type="protein sequence ID" value="ACA88030"/>
        <property type="gene ID" value="Swoo_3771"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3771"/>
    <dbReference type="HOGENOM" id="CLU_1863810_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="14520" checksum="5EA6B6D71CDD95EF" modified="2008-04-29" version="1" precursor="true">MKFGVLILVVLLVACSGNQRQTPVIVADGTEAEQFEKLFFCGDLEGFTKALADVGSKLGDGWEQVEGDDSPHECTVRINIDEAGNIVAHEIVTCDKPSAIPEVLAEASPVPVPENKCMLESINGVKFGLNSGSDSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEP4</accession>
    <name>B1KEP4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Poly(A) polymerase I</fullName>
            <shortName evidence="5">PAP I</shortName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pcnB</name>
        <name evidence="11" type="ordered locus">Swoo_3800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326390.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3800"/>
    <dbReference type="EnsemblBacteria" id="ACA88059">
        <property type="protein sequence ID" value="ACA88059"/>
        <property type="gene ID" value="Swoo_3800"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3800"/>
    <dbReference type="eggNOG" id="COG0617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015961_0_0_6"/>
    <dbReference type="OMA" id="FMAKLDM"/>
    <dbReference type="OrthoDB" id="2018439at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004652">
        <property type="term" value="F:polynucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006378">
        <property type="term" value="P:mRNA polyadenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00957">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010206">
        <property type="entry name" value="PolA_pol_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025866">
        <property type="entry name" value="PolyA_pol_arg_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12626">
        <property type="entry name" value="PolyA_pol_arg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01942">
        <property type="entry name" value="pcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="8">
        <location>
            <begin position="19"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="10">
        <location>
            <begin position="175"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_arg_C" evidence="9">
        <location>
            <begin position="293"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="388"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="421" mass="47948" checksum="71A9612EED72F02F" modified="2008-04-29" version="1">MSENAIKVLYRLHKSGFKAYLVGGGVRDILLGLQPKDFDVVTNATPEEIKRLFRNCRLVGRRFRLAHIVFGRDVIEVATLRGHHVDNEEKISKTNAEGRLLRDNVYGTIDEDAERRDFTVNALYYDISDFSIHSYGGGLEDLHSRTIRMIGDPNTRYREDPVRMLRAVRFATKLGMTVDEETAAPIYELAPLLKDIPAARMYEEVLKLFFNGQAENNFAMMRDFGLFAPLFPLVETLLTEDAKGPATKMLQVIMKNTDARVQAEKTVTPAFFYAAILWYPLAQKADDIALESGLSLYDAYYAAMGDIMEQQCRTISIPRRFSTPAKDIWQLQLRFDRNQGTRAFKFIEHPKFRAAYDLLLLRADAEGGSVAKSAAWWKSFVEAGEEQRSVIARSTNKGSRNRNSNQRKRRKPANKTAKPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEP8</accession>
    <name>B1KEP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326394.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88063">
        <property type="protein sequence ID" value="ACA88063"/>
        <property type="gene ID" value="Swoo_3804"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3804"/>
    <dbReference type="eggNOG" id="ENOG5031FQ8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1561824_0_0_6"/>
    <dbReference type="OMA" id="EYSQHKI"/>
    <dbReference type="OrthoDB" id="1556152at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="172" mass="20153" checksum="7A680A746294F53B" modified="2008-04-29" version="1" precursor="true">MAKPSVIVTIISLFIVYSAQANVIYKCIKGEKIVFSQTVCPKEFNQRKIEFQLGITTETDSDKREKIVDPIHQLLTEDTMPKKQQLKQLKAEIYRLNQENSYFEILRANALQKIKRKNYWQKKDTKDPEYVAETAEVNSYFNDMVADNNKIISLLNTRKDQIIMEQENKEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER7</accession>
    <name>B1KER7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326413.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3823"/>
    <dbReference type="EnsemblBacteria" id="ACA88082">
        <property type="protein sequence ID" value="ACA88082"/>
        <property type="gene ID" value="Swoo_3823"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3823"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_10_6"/>
    <dbReference type="OMA" id="KLMISHE"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="12"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="156"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="40096" checksum="8608D088EFBC6EBF" modified="2008-04-29" version="1">MAFSGGALGKVNVVICDDSITNVLVMNEMLKTIDMNLSITSITDPRKVMAELEFDVMLVILDLEMPHLSGYQVLEQIRARYNSEELPVIVVSGLSDQKSHIKALKGGANDFVCKPFNEYELKLRVMNQLNIIQTLRLQTHLNQELESRVLQRTFELDQATEFLINKLAIVAELHDETTGKHIIRVGKYSGLLARKLGLNEQIVYMIEKAAPMHDIGKLMISHEVLVKPDKLSNEEFLHMQQHVDKVNVLFDDHPSMMIQMAQSIAIHHHEKWDGSGYSKGLTGQSIPIEGRIVCIADVFDALTTKRPYKPAWSFDESINYLKEQAGSHFDPQLVELFVGSIPEIKAIQEEYKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU1</accession>
    <name>B1KEU1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326436.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3848"/>
    <dbReference type="EnsemblBacteria" id="ACA88106">
        <property type="protein sequence ID" value="ACA88106"/>
        <property type="gene ID" value="Swoo_3848"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3848"/>
    <dbReference type="eggNOG" id="COG1765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100275_2_0_6"/>
    <dbReference type="OMA" id="HDNAIAW"/>
    <dbReference type="OrthoDB" id="1430018at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="19423" checksum="81EF7EC19294C005" modified="2008-04-29" version="1">MNNLPLNGIKLDDLAAYTQVITDNPAEAISEYGIVAQWKGGVHSEIRTLNQKVGGKEIVKDFRFQVGEPEELLGNNAYPTPQDYLLGGMAGCMMVGFVAGASARGIKLDEVSLTIKGALNLRGFLNVDPDAPVGFAEVKFHFEVKGDSTQAVYDEVIAGVQQFSPNYRTISDAVKVSATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV5</accession>
    <name>B1KEV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323453.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0811"/>
    <dbReference type="EnsemblBacteria" id="ACA85106">
        <property type="protein sequence ID" value="ACA85106"/>
        <property type="gene ID" value="Swoo_0811"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0811"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_6"/>
    <dbReference type="OMA" id="PKLAFPT"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="32551" checksum="E909A569B28E6A5F" modified="2008-04-29" version="1">MDIKLQQLRYFSLVAEKGGFRAASDTANRSQAALSTSVKELEKILGQALFDTGHKAQLTPYGEVCLPMVNQFLNLYQSLDSDLRAAAKGEFGRLKIASVPSVAAKLLPKVLAAFCNNHPEVQVSLIDDNAVGIEKRLLAGEVDLALGNCLHASDHRIEFSPLFTDPLGLVCQKDHPLASKHQGVDWTDIIPFPFIKNGTCRLLATTPAAVLAEQANYDVENITSLFSVLELGVGVTTLPKLAFPIENKNLVWIPLKRPFIEREIGIFRSIERHLSPQADAFLQLCQTQFEACNTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEZ3</accession>
    <name>B1KEZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323491.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85144">
        <property type="protein sequence ID" value="ACA85144"/>
        <property type="gene ID" value="Swoo_0849"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0849"/>
    <dbReference type="HOGENOM" id="CLU_2397969_0_0_6"/>
    <dbReference type="OrthoDB" id="2192356at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="93" mass="10319" checksum="FF2CA8C27A734E4E" modified="2008-04-29" version="1">MKQEQDLTEAELINIGEILEQYQGKMLKEIESVIEKHVQAASSELVSTNPELANYDYFSAVVLGELFSKLHGGNKDTAEIIMHNLQGQAGLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF25</accession>
    <name>B1KF25_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323523.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0882"/>
    <dbReference type="EnsemblBacteria" id="ACA85176">
        <property type="protein sequence ID" value="ACA85176"/>
        <property type="gene ID" value="Swoo_0882"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0882"/>
    <dbReference type="eggNOG" id="ENOG502ZYSI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128767_0_0_6"/>
    <dbReference type="OMA" id="FDMQIVD"/>
    <dbReference type="OrthoDB" id="2073092at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="180" mass="20218" checksum="0797895C0742C1CA" modified="2008-04-29" version="1">MNKSQQFFCFGKRVWFLVFALLVIVGLCIGLHYFFVPEENVSLSCRAALYSEDINRDLDVGLEIEARGELVTLQYRFFESGLEKSSMILSGKVSKLDLSSMSLKLELDNGQVVSNLAQARLSKHMKTIIDASRLAITNGTPLSLGINLVELDEKDNYAIIQFLPDDGLWGCHLKLHKLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFA1</accession>
    <name>B1KFA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2363</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2363"/>
    <dbReference type="EnsemblBacteria" id="ACA86642">
        <property type="protein sequence ID" value="ACA86642"/>
        <property type="gene ID" value="Swoo_2363"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2363"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_294719_0_0_6"/>
    <dbReference type="OMA" id="RYLGLEM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764790" evidence="2">
        <location>
            <begin position="42"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="742"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="771"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="806"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="832"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="873"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3857" evidence="4">
        <location>
            <begin position="92"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="3">
        <location>
            <begin position="316"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1028" mass="117532" checksum="92C490505845FEA1" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFG5</accession>
    <name>B1KFG5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3882"/>
    <dbReference type="EnsemblBacteria" id="ACA88140">
        <property type="protein sequence ID" value="ACA88140"/>
        <property type="gene ID" value="Swoo_3882"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3882"/>
    <dbReference type="eggNOG" id="ENOG5032YVH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179405_0_0_6"/>
    <dbReference type="OMA" id="WWNLVGA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019629">
        <property type="entry name" value="Uncharacterised_HI1736/YgjV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10688">
        <property type="entry name" value="Imp-YgjV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="92" mass="10099" checksum="1B0752E24BAB7463" modified="2008-04-29" version="1">MAIITLGSIGELMDSATIWEWVGYLASVVVAISLMMSNIKKLRWWNLIGAALFVAYGLAIGAIPVALVNFFIVLIDAYYLVKLYKEEQAVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFG6</accession>
    <name>B1KFG6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326471.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3883"/>
    <dbReference type="EnsemblBacteria" id="ACA88141">
        <property type="protein sequence ID" value="ACA88141"/>
        <property type="gene ID" value="Swoo_3883"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3883"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_13_1_6"/>
    <dbReference type="OMA" id="TTQVWQI"/>
    <dbReference type="OrthoDB" id="2060970at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="57"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="15570" checksum="17BAE8B4A5719389" modified="2008-04-29" version="1">MSIWFRPVSLEDCAKMDSGMHGKGTLMQTMGIKISEIGDDYMKATMPATPAIHNPLGIVHGGANVALAETVASYAANFAVDFEQYYCVGQEINANHLKASRNGTLTATAKAVHLGKRSSVWEVLIHNSAGELCCISRMTAAVVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK0</accession>
    <name>B1KFK0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326505.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3917"/>
    <dbReference type="EnsemblBacteria" id="ACA88175">
        <property type="protein sequence ID" value="ACA88175"/>
        <property type="gene ID" value="Swoo_3917"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3917"/>
    <dbReference type="eggNOG" id="ENOG5032U2Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182378_0_0_6"/>
    <dbReference type="OMA" id="NNADGRH"/>
    <dbReference type="OrthoDB" id="1989364at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="82" mass="9189" checksum="1AC9932434D5E1BD" modified="2008-04-29" version="1">MNDEQNIIDNLDDLRRFLVSVETGGLGLQGVEGVGMATNNADGRHFVAVFDANHKLLHARWVTDEVYENGKEMVRDGVRPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK6</accession>
    <name>B1KFK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326511.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3923"/>
    <dbReference type="EnsemblBacteria" id="ACA88181">
        <property type="protein sequence ID" value="ACA88181"/>
        <property type="gene ID" value="Swoo_3923"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3923"/>
    <dbReference type="HOGENOM" id="CLU_1015251_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764388" evidence="1">
        <location>
            <begin position="24"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="274" mass="30112" checksum="69EEC9C44F2081D6" modified="2008-04-29" version="1" precursor="true">MRTITLALIPFLALTHLSGCSNAVTYHHSERNSIALETRATDPQQPVQGTIGIKTRTIVVTPKVDKTNGNATNVVSDFELKRKSSGHWYGTTEINSAFMTGKAAKDASTRSILAVKGGLGSGHLGPLNTHKKMILQNMYDTLVDLTEDKGAVKLQTQLDNLHKLLPDVSKMTFYHLTNSKKNLTDVKGNQVNSISADFNGVMNYLELVDTSLLALNYMLNNRAVTYKSKDIDGTQLNSLKQAKELKNKEREAFNTTIGNSPSIDNTITFITDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN8</accession>
    <name>B1KFN8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RelA_SpoT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0910"/>
    <dbReference type="EnsemblBacteria" id="ACA85204">
        <property type="protein sequence ID" value="ACA85204"/>
        <property type="gene ID" value="Swoo_0910"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0910"/>
    <dbReference type="eggNOG" id="COG2357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097578_0_0_6"/>
    <dbReference type="OMA" id="ILYSKAH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766553" description="RelA_SpoT domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="RelA_SpoT" evidence="2">
        <location>
            <begin position="106"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="266" mass="30168" checksum="09D37F0643EBA59E" modified="2008-04-29" version="1" precursor="true">MFMNSMNKLFRTFFIFLLLLSTRTGFAATHEFQSQIKEKSDNYAVRQSLPKNLTGLYSISSHQQHTPRQTSSDLDSLYSTAQPAQNELNHIINTITQQGSLNASLPPIKTYERALNKVTTKFDGDASQLTDLARASILANNIHDLMQAYQTLSEQTQVLQVKNRFSSPKESGYRDLNTLIKLPQTGMIVEVQLHLNEIAKIKSGPEHKAYEEIQEIEALANVENRPLFNSETARITELRQSSHKQYHKAWLNYKRIDSAGVLPMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ4</accession>
    <name>B1KFQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0927</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323567.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0927"/>
    <dbReference type="EnsemblBacteria" id="ACA85220">
        <property type="protein sequence ID" value="ACA85220"/>
        <property type="gene ID" value="Swoo_0927"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0927"/>
    <dbReference type="eggNOG" id="COG0421">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060070_2_1_6"/>
    <dbReference type="OMA" id="HFDAGIK"/>
    <dbReference type="OrthoDB" id="1613081at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="4">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="247" mass="27887" checksum="62F78B9000EF0426" modified="2008-04-29" version="1">MTELETLYQSEDEYGPLLVLEDKHMRVLSFGDNDEQSKLLKLQPFLPQHTYVQAMLLVLLFIKPKRVVILGLGGGGLIHALRHYDAGIKITAVELRAQVIEIAKRFFQLPIGKKLTLIHQDAAEFLEQAEHKKADVIFADIYGADGVDENQLSDAFIKNAAMMIKADGFLVLNCWKEHSQNRELLSLLQTYFVEVRACLTGGGNWVVFASKTKRDITSSGMKAKAHSLSLQLDFTLSRSLTRFDHWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG55</accession>
    <name>B1KG55_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_2485</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-alanine + NAD(+) = H(+) + NADH + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18405"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="1.4.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="2 5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325104.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2485"/>
    <dbReference type="EnsemblBacteria" id="ACA86762">
        <property type="protein sequence ID" value="ACA86762"/>
        <property type="gene ID" value="Swoo_2485"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2485"/>
    <dbReference type="eggNOG" id="COG0686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003376_3_0_6"/>
    <dbReference type="OMA" id="HPYYHLY"/>
    <dbReference type="OrthoDB" id="673280at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000183">
        <property type="entry name" value="Alanine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00518">
        <property type="entry name" value="alaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="9">
        <location>
            <begin position="149"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="267"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="298"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="371" mass="39424" checksum="1BDD0C9D35FF9D9C" modified="2008-04-29" version="1">MIIGVPKEIKNHEYRVGMVPSSVRELTIKGHKVFIETNAGSGIGFTDQDYIDVGASILATAAEVFATADMIVKVKEPQAVERAMLREDQLLFTYLHLAPDLPQTEDLVKSGSVCIAYETVTDDRGTLPLLAPMSEVAGRMSIQAGAMALEKSMGGRGMLLGGVPGVEPAKVVIIGGGMVGTNAAQMAVGLGADVVILDRSIDALRRLNAQFDNKVKAIYSTADAIEKHVLEADLVIGGVLVPGAAAPKLVTKEHIKSMKPGSAIVDVAIDQGGCIETSHATTHQDPTYIVDDVVHYCVANMPGAVARTSTFALNNATLPYIIKLADLGYRDALLNDKHLLNGLNVMHGKITCLEVAEALNFEFVDPKILLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE6</accession>
    <name>B1KGE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-oxoprolinase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="2">3.5.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.2.9" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326612.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4027"/>
    <dbReference type="EnsemblBacteria" id="ACA88283">
        <property type="protein sequence ID" value="ACA88283"/>
        <property type="gene ID" value="Swoo_4027"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4027"/>
    <dbReference type="eggNOG" id="COG0146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020413_1_1_6"/>
    <dbReference type="OMA" id="GETYNCP"/>
    <dbReference type="OrthoDB" id="1018930at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase_B" evidence="1">
        <location>
            <begin position="5"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="558" mass="60149" checksum="00E9AB0CAD82C5B4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGJ0</accession>
    <name>B1KGJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323665.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1025"/>
    <dbReference type="EnsemblBacteria" id="ACA85318">
        <property type="protein sequence ID" value="ACA85318"/>
        <property type="gene ID" value="Swoo_1025"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1025"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023673_0_0_6"/>
    <dbReference type="OMA" id="EAMHIGF"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="260"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="489" mass="54829" checksum="CE77CA796B17EEE1" modified="2008-04-29" version="1">MQDIRDLTSVLRSNTPIVVIETYEEHRAIELLKKVSSVLYQPLFSWSITQGLTRVDRAMGVQKFNCEPADILGQIKSTDQQGIYVLCDFHPFVENAPKNVRLLKEIALEYESLKHTLVLVSHAFEIPPEIKRYCAHFRLSLPNGAQLQNLIYEQVDKVRAEGVMLDVDDSAVLKLAENLKGLTFDDARRLAHKAIVDDGAITHSDIDMVNKGKFELLDMEGILQFEYDTSDFSQVAGLHNLKQWLKHRTPSTCTQNLEDQPKGILLLGVQGSGKSLAAKAVAGMWQRPLLRLDMSALYNKYIGETEKNLRHALELADLMSPCVLWIDEIEKGLGGGSSDDGVSTRILGTILTWMAERKSQVFMVATANDISALPPELMRKGRMDEIFFVDLPDDEIRKAIFLIHAKRRGLDLSKFNLAELSNASQGFSGAEIEQAIISAIYTARASELTLDQGLLIDELMKTRPLSVVMREKLDALRKWASGRTVNAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN3</accession>
    <name>B1KGN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Superoxide dismutase, Ni</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323707.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1068"/>
    <dbReference type="EnsemblBacteria" id="ACA85361">
        <property type="protein sequence ID" value="ACA85361"/>
        <property type="gene ID" value="Swoo_1068"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1068"/>
    <dbReference type="eggNOG" id="ENOG502ZR3M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141681_0_0_6"/>
    <dbReference type="OMA" id="AHCDGPC"/>
    <dbReference type="OrthoDB" id="1789560at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036502">
        <property type="entry name" value="NiSOD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014123">
        <property type="entry name" value="Superoxide_dismutase_Ni-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09055">
        <property type="entry name" value="Sod_Ni"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109770">
        <property type="entry name" value="SSF109770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02753">
        <property type="entry name" value="sodN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="166" mass="19149" checksum="283D849D73273B30" modified="2008-04-29" version="1">MLYTLLNLRDKNRPFTRVSAHCDIPCKIYDPITAQLAVLTMIRMVDLLEELSAKPEPSPNDHAQFSRLVAEKESHGRKVKDEINVIWGDYIKQPQLELFPELHELTHSIMLNASQAKQHISREACLTLLEKVNRFADIFWQTKGLETYQATCPYPPSETLVYPKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN4</accession>
    <name>B1KGN4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323708.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1069"/>
    <dbReference type="EnsemblBacteria" id="ACA85362">
        <property type="protein sequence ID" value="ACA85362"/>
        <property type="gene ID" value="Swoo_1069"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1069"/>
    <dbReference type="eggNOG" id="ENOG50312P1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_204336_0_0_6"/>
    <dbReference type="OMA" id="WSASLIH"/>
    <dbReference type="OrthoDB" id="2093937at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764446" evidence="2">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="67" mass="7398" checksum="2261DD7D948C357A" modified="2008-04-29" version="1">MKNTIATRSMLLLVAALTSPLVAAHPGHDHQHWSASLIHLLWILPAVIAIGALVHLYRRKRTQSDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU7</accession>
    <name>B1KGU7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ordered locus">Swoo_2539</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325157.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2539"/>
    <dbReference type="EnsemblBacteria" id="ACA86816">
        <property type="protein sequence ID" value="ACA86816"/>
        <property type="gene ID" value="Swoo_2539"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2539"/>
    <dbReference type="eggNOG" id="COG0364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013524_5_0_6"/>
    <dbReference type="OMA" id="VEICVYE"/>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="14"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="190"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="490" mass="55841" checksum="BB3FB7A33677CCC8" modified="2008-04-29" version="1">MGITTPEAKACDFVLFGTKGDLARRKLLPSLYQLDKAGLLNEDTKVIGVAKDAFTHEEFNELVVKALRGFVKEELCEETLARFLTRCHYIGTNFTESEGYQAFHELLEPHKRVMVSYFATPPAIFGDICRCLHEQNLIQSDSRVVLEKPIGSDLASSKVINDQVAAFYNEDQVYRIDHYLGKETVQNLIALRFANSLFASKWDNRTIDHVQITVAEEVGIEGRWGYFDKAGQMRDMIQNHLLQVLTLVAMDPPVNLDADSIRDEKVKVLKSLRPINLDNIYENTVRGQYSSGFLKGSPVPGYLEEEGANTQSNAETFVALRVDIDNWRWAGVPFYLRSGKRMPTKSSEIVVYFKNPPHNLYRSNYRNLPPNKLTIRLQPHEGVEIQMMNKVPGLEQKQRLQTTKLDLSFTDTFKNERIADAYERLLLEAMLGNQALFVRRDEVEQAWTWVDGIIQSWEESNEKPKPYPAGSWGPVASVALIAKDGRSWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH49</accession>
    <name>B1KH49_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BLUF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326690.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4105"/>
    <dbReference type="EnsemblBacteria" id="ACA88361">
        <property type="protein sequence ID" value="ACA88361"/>
        <property type="gene ID" value="Swoo_4105"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4105"/>
    <dbReference type="eggNOG" id="COG3431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097099_1_1_6"/>
    <dbReference type="OrthoDB" id="1977204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009882">
        <property type="term" value="F:blue light photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007024">
        <property type="entry name" value="BLUF_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04940">
        <property type="entry name" value="BLUF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01034">
        <property type="entry name" value="BLUF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50925">
        <property type="entry name" value="BLUF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BLUF" evidence="1">
        <location>
            <begin position="10"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="17799" checksum="C42D4355415B5280" modified="2008-04-29" version="1">MREGKQYMPIVQLIYSSSVSEGLSVMEIKALVEKAQINNRALSVTGFLCANSYYFLQCIEGESAVIDALFQKISKDSRHHSITVINKREVDNQQFRAWSMGAVLDIDRHMNIVDGFFPDGVFNPSLLSEQTSLEFIEQFSQIRIRTQERTIESLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH54</accession>
    <name>B1KH54_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Periplasmic nitrate reductase</fullName>
            <ecNumber evidence="12">1.9.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">napA</name>
        <name evidence="15" type="ordered locus">Swoo_4110</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(II)-[cytochrome] + 2 H(+) + nitrate = 2 Fe(III)-[cytochrome] + H2O + nitrite</text>
            <dbReference type="Rhea" id="RHEA:12909"/>
            <dbReference type="Rhea" id="RHEA-COMP:11777"/>
            <dbReference type="Rhea" id="RHEA-COMP:11778"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.9.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
        <text evidence="12">Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.9.6.1" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326695.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4110"/>
    <dbReference type="EnsemblBacteria" id="ACA88366">
        <property type="protein sequence ID" value="ACA88366"/>
        <property type="gene ID" value="Swoo_4110"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4110"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_13_4_6"/>
    <dbReference type="OMA" id="FNFYGKP"/>
    <dbReference type="OrthoDB" id="323168at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050140">
        <property type="term" value="F:nitrate reductase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02791">
        <property type="entry name" value="MopB_CT_Nitrate-R-NapA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01630">
        <property type="entry name" value="Nitrate_reduct_NapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041957">
        <property type="entry name" value="CT_Nitrate-R-NapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010051">
        <property type="entry name" value="Periplasm_NO3_reductase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01706">
        <property type="entry name" value="NAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11 12" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 12" id="KW-0574">Periplasm</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="14">
        <location>
            <begin position="39"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="12">
        <location>
            <begin position="212"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="12">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="12">
        <location>
            <begin position="508"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="12">
        <location>
            <begin position="716"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="531"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="792"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="800"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="817"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA88366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="826" mass="92553" checksum="AE01EE0D43022D48" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH67</accession>
    <name>B1KH67_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Carbamoyl-phosphate synthase L chain ATP-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326708.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4123"/>
    <dbReference type="EnsemblBacteria" id="ACA88379">
        <property type="protein sequence ID" value="ACA88379"/>
        <property type="gene ID" value="Swoo_4123"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4123"/>
    <dbReference type="eggNOG" id="COG0439">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0777">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003206_0_0_6"/>
    <dbReference type="OMA" id="SIDPLMP"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="9">
        <location>
            <begin position="56"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin carboxylation" evidence="8">
        <location>
            <begin position="939"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="1061"/>
            <end position="1259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1518" mass="167901" checksum="80E30FD0EBB8BDB1" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ4</accession>
    <name>B1KHJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2602"/>
    <dbReference type="EnsemblBacteria" id="ACA86879">
        <property type="protein sequence ID" value="ACA86879"/>
        <property type="gene ID" value="Swoo_2602"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2602"/>
    <dbReference type="eggNOG" id="ENOG502ZCIW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048424_0_0_6"/>
    <dbReference type="OMA" id="QFYNASP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766613" evidence="1">
        <location>
            <begin position="27"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="460" mass="52289" checksum="406FBC1C551EC90D" modified="2008-04-29" version="1" precursor="true">MKELKMKKIKNFTLLFFLSLCLISCGGSDNDESKPDVTYIQYYNASPDSTSTYLSLTKKKYSKVNFGYANSRVAVTTGSNKLTIVGTDAKNKEVKFHQKDIDFEAQSYHLFVLTGKYADSGFLDLKYSQDKLIKENEENKEKKITKMQVIAAHVSQGVQDFDIYVGKKEDGFSSAKYLGKLKYLGVSSPEILVNGKYVVYLAKAGGNEPIFTTKEIDLKLQTTYKLMIRPGFGQSKYGVKLDVVSSSKTVSSYPDINESVQFRVYDGFEHSAQLQVMLKGKDGEEKKQDVTRWQVSAFTPTKFGDYDVSVSDPVTGEQLLDNLLVTYNQSDSKTILFYPTKEKKLKASVIEHNLTPRSYEYQAKLVNLATDKNGLEVYFVRNNETVETAKHFIKKWNFLKTKSLTLPRDKYTVTLVEKKTDGTLNLLHRQTLELKDNLDYTLVLTPDASEQWGYRLTAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHK2</accession>
    <name>B1KHK2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325227.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2610"/>
    <dbReference type="EnsemblBacteria" id="ACA86887">
        <property type="protein sequence ID" value="ACA86887"/>
        <property type="gene ID" value="Swoo_2610"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2610"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075049_1_0_6"/>
    <dbReference type="OMA" id="CEEQAWP"/>
    <dbReference type="OrthoDB" id="1730305at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="73"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="28353" checksum="9B5CA044655B18B3" modified="2008-04-29" version="1">MPDNAQPLSPQLWSQLPSGDQIKSLIEHILTPWWPKVFGYHMLNLGALSAELDMPDLPIGRRFSLFDGKGASIRAEFTALPIQNSVIDAVVMNMLLEFEPDPYKLLRETDRVLISGGYLFIIGFNPLSPAFIGKLLPKYQQQQPWNGRFFMPSRVKDWLGLLGYQVISDERFLYHHLLSDIKSESIWQDALQAWLPSSGSLYLIVARKLESPLTPIHEKRKVRQTQWTTAPTAGRSEHFNQKHKTDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR1</accession>
    <name>B1KHR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyribonuclease I</fullName>
            <ecNumber evidence="3">3.1.21.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EndA/NucM nuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4133"/>
    <dbReference type="EnsemblBacteria" id="ACA88389">
        <property type="protein sequence ID" value="ACA88389"/>
        <property type="gene ID" value="Swoo_4133"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4133"/>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070541_0_0_6"/>
    <dbReference type="OMA" id="QSTEFYC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004530">
        <property type="term" value="F:deoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
        <property type="entry name" value="PTHR33607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04231">
        <property type="entry name" value="Endonuclease_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766620" evidence="2">
        <location>
            <begin position="28"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="28770" checksum="C580DA8CA9C4FE28" modified="2008-04-29" version="1" precursor="true">MKSLTKIGPAFLIGLGLSLLFSAPTFASGSHPSSFYQAKKRAKEIYARSLPATSFYCGCDIKINGKKWQTDFETCGYQVRKQEKRAARIEWEHIVPAWEFGHQRQCWQEGGRKNCGKKDQQFKKMESDLHNLVPAIGEVNGDRSNYRFSQWNASPEQYGQCAMVVDFKSRKAEPPSYTRGQIARTYLYMQQAYGLKIAKSQLKLFKAWDKTYPVDTIECKRDREIARTQGNHNPFVKNLCDAQARTQSLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT4</accession>
    <name>B1KHT4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FxsA cytoplasmic membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326741.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4156"/>
    <dbReference type="EnsemblBacteria" id="ACA88412">
        <property type="protein sequence ID" value="ACA88412"/>
        <property type="gene ID" value="Swoo_4156"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4156"/>
    <dbReference type="eggNOG" id="COG3030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085083_0_1_6"/>
    <dbReference type="OMA" id="FQQVRIH"/>
    <dbReference type="OrthoDB" id="2002498at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007313">
        <property type="entry name" value="FxsA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35335">
        <property type="entry name" value="PTHR35335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04186">
        <property type="entry name" value="FxsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20271" checksum="2B8B67F22FB2E721" modified="2008-04-29" version="1">MFFVFIVIFILVPVVELNVLIKVGESLGSWTTVGLVFFTAIVGVSLVRSQGISTLMQVQQKLARGEAPGQEIVEGMMLAVAGLLLLIPGFVTDFIGLVLLTPFTRIPVAGFLYKRMQVKVAANGGFQGGFGPGGFSRGGSPFGNDPFKRDSQNPEGGDTFDGDFEHKRDPNEHRVEHKEDSKEDPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHX6</accession>
    <name>B1KHX6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326783.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4198"/>
    <dbReference type="EnsemblBacteria" id="ACA88454">
        <property type="protein sequence ID" value="ACA88454"/>
        <property type="gene ID" value="Swoo_4198"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4198"/>
    <dbReference type="eggNOG" id="COG2847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100939_1_2_6"/>
    <dbReference type="OMA" id="LHIMLFD"/>
    <dbReference type="OrthoDB" id="1872498at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007410">
        <property type="entry name" value="PCuAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036182">
        <property type="entry name" value="PCuAC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36302">
        <property type="entry name" value="PTHR36302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04314">
        <property type="entry name" value="PCuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110087">
        <property type="entry name" value="SSF110087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17465" checksum="BA58A36A23A10346" modified="2008-04-29" version="1" precursor="true">MEFNTLKQIFKQVFNLLVLMSISFSSLASVMLVDGHIRAMPPSVPNSAAYFTLMNHGPSIKLVGVETTFTDEAQLHTVLDEDGMVKMRQVSSFEIPKHGTLALNESGEHVMLMGLKQPLVSGETLELVLIFDDGSKLPINLVVSKQGMAKMHSHDHHH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY4</accession>
    <name>ALR_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alanine racemase</fullName>
            <ecNumber evidence="1">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">alr</name>
        <name type="ordered locus">Swoo_4206</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alanine racemase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326791.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHY4"/>
    <dbReference type="SMR" id="B1KHY4"/>
    <dbReference type="STRING" id="392500.Swoo_4206"/>
    <dbReference type="EnsemblBacteria" id="ACA88462">
        <property type="protein sequence ID" value="ACA88462"/>
        <property type="gene ID" value="Swoo_4206"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4206"/>
    <dbReference type="eggNOG" id="COG0787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028393_1_0_6"/>
    <dbReference type="OMA" id="WEILCGF"/>
    <dbReference type="OrthoDB" id="859043at2"/>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020622">
        <property type="entry name" value="Ala_racemase_pyridoxalP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00395">
        <property type="entry name" value="ALANINE_RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000164625" description="Alanine racemase">
        <location>
            <begin position="1"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="1">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="1">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <sequence length="358" mass="38900" checksum="662B881D66023D52" modified="2008-04-29" version="1">MKPFPRAEISAQALKNNLSRLRQIAPNSSVMAVVKANGYGHGLLNVASCLTEADGFGLARLEEALALRAGGVKAKLVLLEGFFRQVDLTTLVEHGIDTVIHNEVQLDMLENASLSKPVTVWLKLDSGMHRLGFTPEQFAQVYARLEACPQVAKPINIMSHFACADEPDNPMTQEQLQVFEALTKNSKGYRTLANSAGTLYWPDSQADWIRPGIALYGVSPVIGDLGRNHGLEPAMKLVSQLIAVREHKAGQPVGYGCFWHAKADTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPVVGRVSMDMLTVDLGIDAKDSIGDDVVLWGKELPVEEVAEHIGTIAYELVTKLTPRVAVCLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ1</accession>
    <name>B1KHZ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326797.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4213"/>
    <dbReference type="EnsemblBacteria" id="ACA88469">
        <property type="protein sequence ID" value="ACA88469"/>
        <property type="gene ID" value="Swoo_4213"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4213"/>
    <dbReference type="eggNOG" id="COG3137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058997_5_1_6"/>
    <dbReference type="OMA" id="LFQDWAF"/>
    <dbReference type="OrthoDB" id="1623492at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007433">
        <property type="entry name" value="DUF481"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04338">
        <property type="entry name" value="DUF481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766634" evidence="1">
        <location>
            <begin position="19"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="249" mass="28056" checksum="6698D940CCDAE15A" modified="2008-04-29" version="1" precursor="true">MFRAIAVLFLTFPMTAWALVPPDYQEPPSDFTAEIEAGFQLNTGNTDSSSFNGRTKLVYDTKQTKQEATFKAYFASDDEKTTSEKYDIQLQSNYKLQSDWGGYVFGRGDFTSDRFGSYTQISTVSTGYGFDAISDIDTKLSLEIGPGYRYNMPIETEAEPDPEANADVIIRTAIKFEQKLQEYTSLNADLTAEAGEDNSTLTLDMNYKNTLFQDWAFKIGVNVKYTDVVPEGTKQTDTITTFNLLYTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI22</accession>
    <name>B1KI22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alkaline phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1207</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323846.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1207"/>
    <dbReference type="EnsemblBacteria" id="ACA85500">
        <property type="protein sequence ID" value="ACA85500"/>
        <property type="gene ID" value="Swoo_1207"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1207"/>
    <dbReference type="eggNOG" id="COG1785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008539_6_2_6"/>
    <dbReference type="OMA" id="GYNTTPV"/>
    <dbReference type="OrthoDB" id="585847at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764899" evidence="7">
        <location>
            <begin position="25"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="464" mass="51278" checksum="7AEC413ED8559153" modified="2008-04-29" version="1" precursor="true">MFHLNKRLTLSAICCSILSMQVLAQSPQSSLEMATVQLPKNIIYLIGDGMGPAYTSAYRYYADNPETKTVEKTIFDRLLVGSSSTYPDDDTYVTDSAASATALATSHKTYNGAISVDHQHTPITTFFEIAKAQGKTTAVVVTSQINHATPASFLAHNESRRNYDEIADSYLDNLINGQPIADLMLGGGTKYFVREDRDLTQEFTQLGYQYIDKLDELDTIESLPALGLFAPKGLSYALGSDDPLRLTTMTRKSLDLLSAKKSSFVLMIEASQIDWCGHKNDIVCAMGEMHDFANTLELVKAFIDANPDTLLIATADHSTGGLTLGRSGKYQWKGKLLQQVTTLPNVIARQLMDDTSVLEKSESFSTFLAHHIQFEIDARAMNSLRIILKDGIKQAKALKVIEKELKHFIDKATYTGWTTGGHTAIDVPIFAYGKGQQYFSGHMDNTEIAAKLIEIMTPQRVNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI46</accession>
    <name>B1KI46_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323870.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1232"/>
    <dbReference type="EnsemblBacteria" id="ACA85524">
        <property type="protein sequence ID" value="ACA85524"/>
        <property type="gene ID" value="Swoo_1232"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1232"/>
    <dbReference type="eggNOG" id="ENOG5033NJ6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1958066_0_0_6"/>
    <dbReference type="OMA" id="VDGALMY"/>
    <dbReference type="OrthoDB" id="1762971at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767368" evidence="1">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="14102" checksum="B42DA2D89A30902B" modified="2008-04-29" version="1" precursor="true">MRNLMLVSALCLGIVPTASASQLDACNSEVQSESCQHYLEGVVDGALMYKPNAVGARIETDSYESRALKYRGGKRFQEANRTYCEGRIPDREILVNGLGEAFSAGNIKRVEMLNEVMYSLMDCQRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA2</accession>
    <name>B1KIA2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325293.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86953">
        <property type="protein sequence ID" value="ACA86953"/>
        <property type="gene ID" value="Swoo_2677"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2677"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_2_6"/>
    <dbReference type="OMA" id="MTWNESG"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="314" mass="36508" checksum="0E421152BA5BD22E" modified="2008-04-29" version="1">MKNFDFNLLTVLEVLLEEKSVTSAAARLHLSQSAVSKQLARLRDTFDDKLFERTSHGLRPTPKALALAPELRQVLNQVSQLTRPSDFEPELSQRKFRIHMVETAYSLTYPYFMPELLQQAPKIKLDSQTWHHNSMEMLLRCEVDLGIACREWDNRSLMHIKNIPDELEYVELLRDHPICLVSNHHPLLKEPWNLDTFLKYRHLQVTFGGIEHWLLDDVLKLSHLDRDIAVNMSDFTSAMQLCEQSELLLCCPAKYASQMSQNYALTTLTVPTDLIPGAYVLFWHKHFNFDLSHSWLRELIATRTIAYHQANLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA9</accession>
    <name>B1KIA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325300.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2684"/>
    <dbReference type="EnsemblBacteria" id="ACA86960">
        <property type="protein sequence ID" value="ACA86960"/>
        <property type="gene ID" value="Swoo_2684"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2684"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_2_6"/>
    <dbReference type="OMA" id="MASTVIC"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="237"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="371" mass="42264" checksum="6CF30D368F870380" modified="2008-04-29" version="1">MKQREVIRLNEALIVQSNAEIVKGFGWFVHFSCIFFLFIAVISLLKVDTNANRDYLQIVFGVSGAVFVISYLRIAIKKFNYDDLKLAYINLFFILFAWLLLMLGLIAVGDEFWPYVDFIAFTLLISLLTCFYPNSRFFYSGLLFICLSMVTMHLYIRNEDILMFLGSYLIVSFVLNCCRVSFAQHFYDGLASQHENTLLLSKLENLAMRDGLTGINNRKYLDDRLNIEIKRAKRCGKPLSMILLDVDHFKRYNQSVGHQAGDLCLIDIANLIQGCIQRPDDMLARYGGEEFAILLPDTGLESAVRIAKKVQTKLKEAKILHPDSPLSGWTTLSQGITVWEQGMSANIFLKQVDKALSDAKLAGRNCYVVYS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE1</accession>
    <name>PSRP_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative phosphoenolpyruvate synthase regulatory protein</fullName>
            <shortName evidence="1">PEP synthase regulatory protein</shortName>
            <shortName evidence="1">PSRP</shortName>
            <ecNumber evidence="1">2.7.11.33</ecNumber>
            <ecNumber evidence="1">2.7.4.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Pyruvate, water dikinase regulatory protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_2716</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]-phosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46020"/>
            <dbReference type="Rhea" id="RHEA-COMP:11425"/>
            <dbReference type="Rhea" id="RHEA-COMP:11426"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[pyruvate, water dikinase]-phosphate + H(+) + phosphate = [pyruvate, water dikinase] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:48580"/>
            <dbReference type="Rhea" id="RHEA-COMP:11425"/>
            <dbReference type="Rhea" id="RHEA-COMP:11426"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="EC" id="2.7.4.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.33" evidence="1"/>
    <dbReference type="EC" id="2.7.4.28" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325329.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIE1"/>
    <dbReference type="SMR" id="B1KIE1"/>
    <dbReference type="STRING" id="392500.Swoo_2716"/>
    <dbReference type="EnsemblBacteria" id="ACA86992">
        <property type="protein sequence ID" value="ACA86992"/>
        <property type="gene ID" value="Swoo_2716"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2716"/>
    <dbReference type="eggNOG" id="COG1806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046206_1_0_6"/>
    <dbReference type="OMA" id="YAQCEFE"/>
    <dbReference type="OrthoDB" id="980472at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016776">
        <property type="term" value="F:phosphotransferase activity, phosphate group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01062">
        <property type="entry name" value="PSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005177">
        <property type="entry name" value="Kinase-pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026530">
        <property type="entry name" value="PSRP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31756">
        <property type="entry name" value="PTHR31756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03618">
        <property type="entry name" value="Kinase-PPPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000136497" description="Putative phosphoenolpyruvate synthase regulatory protein">
        <location>
            <begin position="1"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="150"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01062"/>
        </source>
    </evidence>
    <sequence length="270" mass="30719" checksum="A409DE418D8760D0" modified="2008-04-29" version="1">MLRKVFYISDGTAITAEVFGHAVLSQFPVEFEALTIPFVETESKANEVKAQINDCFITTGERPLVFHSIVKAEIRDIIYSSEGLDYDFLNTFVAPLEQQLGISATPVVHRTHGNMNESYEARIDAINYAMDNDDGQTLKHIDKADLVLLGVSRCGKTPSSLYLSMQFGIKAANYPFVEDDMDNLKLPDALKKNKSKLFGLTIDPVRLHEIRQSRMENSRYSSLRQCRIEVKEVEMMYKRERIPFVNTTNHSVEEIATKILAMTGLERHMF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIT2</accession>
    <name>RS20_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsT</name>
        <name type="ordered locus">Swoo_1288</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323926.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIT2"/>
    <dbReference type="SMR" id="B1KIT2"/>
    <dbReference type="STRING" id="392500.Swoo_1288"/>
    <dbReference type="EnsemblBacteria" id="ACA85580">
        <property type="protein sequence ID" value="ACA85580"/>
        <property type="gene ID" value="Swoo_1288"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1288"/>
    <dbReference type="eggNOG" id="COG0268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160655_4_0_6"/>
    <dbReference type="OMA" id="GVIHKNA"/>
    <dbReference type="OrthoDB" id="2005443at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33398">
        <property type="entry name" value="PTHR33398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00029">
        <property type="entry name" value="S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000126513" description="30S ribosomal protein S20">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="88" mass="9715" checksum="EA7ECB3BDEA6A733" modified="2008-04-29" version="1">MANSKSAKKRALQSEKRRQHNASRRSMLRSYVKKVIAAIQAGDHAAATEAFNAAQPILDRMATKGLIHKNKAARHKARLNTRIKALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU3</accession>
    <name>B1KIU3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus biogenesis protein PilE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323937.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1299"/>
    <dbReference type="EnsemblBacteria" id="ACA85591">
        <property type="protein sequence ID" value="ACA85591"/>
        <property type="gene ID" value="Swoo_1299"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1299"/>
    <dbReference type="eggNOG" id="COG4968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091705_6_1_6"/>
    <dbReference type="OMA" id="AYPSYTN"/>
    <dbReference type="OrthoDB" id="1857712at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031982">
        <property type="entry name" value="PilE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16732">
        <property type="entry name" value="ComP_DUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="13826" checksum="180E4AE15FCB778D" modified="2008-04-29" version="1" precursor="true">MKMRNGFTLVELMVGIAIIGILTAIAYPSYTEYVAEGARAEAHTSLLRISNLQEQFYLDNRTYTEDMNELGVGADPFVTQSNLYSVDSTGTGSFVLVATALGVQATRDSACATIQITDTGAKTPTECW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ79</accession>
    <name>B1KJ79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325435.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2824"/>
    <dbReference type="EnsemblBacteria" id="ACA87099">
        <property type="protein sequence ID" value="ACA87099"/>
        <property type="gene ID" value="Swoo_2824"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2824"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027555_0_0_6"/>
    <dbReference type="OMA" id="FKAHNAH"/>
    <dbReference type="OrthoDB" id="618655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07129">
        <property type="entry name" value="ALDH_KGSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044151">
        <property type="entry name" value="ALDH_KGSADH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="24"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="521" mass="55559" checksum="1305DCB60120B8AC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA6</accession>
    <name>B1KJA6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326904.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="ESTHER" id="shewm-b1kja6">
        <property type="family name" value="Duf_3530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88578">
        <property type="protein sequence ID" value="ACA88578"/>
        <property type="gene ID" value="Swoo_4325"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4325"/>
    <dbReference type="eggNOG" id="ENOG5032ZR3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_933501_0_0_6"/>
    <dbReference type="OMA" id="NINAAGW"/>
    <dbReference type="OrthoDB" id="2095638at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022529">
        <property type="entry name" value="DUF3530"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12048">
        <property type="entry name" value="DUF3530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766703" evidence="2">
        <location>
            <begin position="31"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="32886" checksum="E39480AC700BAD8D" modified="2008-04-29" version="1" precursor="true">MNLSHALSLLFRYVLSIGALTFAVSSTGLAAEPNSSNSKYSYLPSEEVISIDVGQQKSEVLVRSWMGKKKLGAAIIFSNPGMTADSAGLQAFLRRELPHTGWASIAITPPNKVSTPNFATSPEEVSKAGEGNNDKDGSERVPQYSKEQWVKIREKQEEFIVNTMNKLDEIGSPYQGKRILITTDQGAGFVISMLSKSKLPKPDILVLINPFMSTKTENMALPKQLAELDIPILDIQSSDGHYASQETVTERRLLSPHNEPYRYSQQLMQLNLNQAGAWQTCLDLIEAFAHRINKAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJF8</accession>
    <name>B1KJF8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326956.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4378"/>
    <dbReference type="EnsemblBacteria" id="ACA88630">
        <property type="protein sequence ID" value="ACA88630"/>
        <property type="gene ID" value="Swoo_4378"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4378"/>
    <dbReference type="eggNOG" id="ENOG502Z7VC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_276188_0_0_6"/>
    <dbReference type="OMA" id="PEWNDAN"/>
    <dbReference type="OrthoDB" id="36122at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1147" mass="130687" checksum="58EB6C3851C5C686" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI1</accession>
    <name>B1KJI1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4401</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in formation and maintenance of cell shape.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MreC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326979.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4401"/>
    <dbReference type="EnsemblBacteria" id="ACA88653">
        <property type="protein sequence ID" value="ACA88653"/>
        <property type="gene ID" value="Swoo_4401"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4401"/>
    <dbReference type="eggNOG" id="COG1792">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042663_2_0_6"/>
    <dbReference type="OMA" id="NPFTHRI"/>
    <dbReference type="OrthoDB" id="837894at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038471">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00219">
        <property type="entry name" value="mreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="32746" checksum="544ED0C93E40299B" modified="2008-04-29" version="1">MKPIFARGISNQFRLTLAIILSVILIVANNRLDPVRKSVSSVLSPLQYIANVPGALLDWSAESLATRNMLAQQNKELLRQQLLMSERLQRFEHLRQENDRLRSLLGSPVHMDAKKIVAEVMEVASDPFHQYVVLNHGARSGVFVGQPVVDAQGVVGQVVQVSELSSRVLLISDVTHAIPVRVTRNDVRVVANGTGVLDELELKYVSKSTDIRVGDLLVSSGLGNRFPEGYPVARVMSLVKDDGQNYANVIAQPLAALDRIRYLLLIWPDEPASEALEDETAMILSAAKKAAEKAEVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJJ0</accession>
    <name>B1KJJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324009.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1371"/>
    <dbReference type="EnsemblBacteria" id="ACA85663">
        <property type="protein sequence ID" value="ACA85663"/>
        <property type="gene ID" value="Swoo_1371"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1371"/>
    <dbReference type="eggNOG" id="ENOG5033AJV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045137_3_0_6"/>
    <dbReference type="OMA" id="AVWYAEK"/>
    <dbReference type="OrthoDB" id="2067101at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021836">
        <property type="entry name" value="DUF3429"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11911">
        <property type="entry name" value="DUF3429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15745" checksum="B746BF2D01FD48CB" modified="2008-04-29" version="1">MKTWKILGYMGLIPFVACLYLSEREMVWGIALKSAFIAYSAIILSFIAGTIWRVDRQLQQSHQQIVSNIFSITAFACLLIRHDIALGILATSYLLLFLYEIRFVKQSKLKIDYIIMRFRLTFAVILLHIVALILWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM9</accession>
    <name>B1KJM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-hydroxymuconic semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324048.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1410"/>
    <dbReference type="EnsemblBacteria" id="ACA85702">
        <property type="protein sequence ID" value="ACA85702"/>
        <property type="gene ID" value="Swoo_1410"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1410"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_2_6"/>
    <dbReference type="OMA" id="RAHNFSQ"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017628">
        <property type="entry name" value="OHmuconic_semiald_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03216">
        <property type="entry name" value="OH_muco_semi_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="18"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="488" mass="53250" checksum="804258FF520508D4" modified="2008-04-29" version="1">MSELPILTSYIDGHFINSDTHFDNINPVNGQTIAHISEATPKMIEDAVISARSAQRSTWGKMTVNERCALLHKVADRMAEREEEFIAAEIADTGKSLFQVKTIDIPRGTANFRFFADLAKFNSGETFITDTPTGDKALNYSVNKPLGVVGVISPWNLPLLLATWKIAPAMACGNSVILKPSEETSSTAFLLAQVMDEVGVPKGAFNLILGRGRAVGDALTSHHGIDAITFTGASSTGRQIMRSVADRVKPISFELGGKNSAIVFADADLNKAIKGVTRSSFTNCGQVCLCTEKVYVHHSLFDAFIQGLKHEAEQIKIGYPKDKDVFIGPLVSKVHQQKVLSYYQLAKDEGATFVTGGGVPKFNDERDMGCFIEPTIITGLSDDARVNQEEIFGPICHVSPFDDEDEVIERVNNTDYGLAASVWSENLSRAHRVSPQLDVGLVWVNTWFLRDLRAPFGGVKLSGIGREGGKHSLAFYSEPVNICIHIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR8</accession>
    <name>B1KJR8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sodium/glutamate symporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gltS</name>
        <name evidence="2" type="ordered locus">Swoo_1451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the sodium-dependent transport of glutamate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324087.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85741">
        <property type="protein sequence ID" value="ACA85741"/>
        <property type="gene ID" value="Swoo_1451"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1451"/>
    <dbReference type="eggNOG" id="COG0786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040907_0_0_6"/>
    <dbReference type="OMA" id="TAIVNMT"/>
    <dbReference type="OrthoDB" id="1284248at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015501">
        <property type="term" value="F:glutamate:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015813">
        <property type="term" value="P:L-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02062">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004445">
        <property type="entry name" value="GltS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36178">
        <property type="entry name" value="PTHR36178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03616">
        <property type="entry name" value="Glt_symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00210">
        <property type="entry name" value="gltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0915">Sodium</keyword>
    <keyword evidence="1" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="1" id="KW-0769">Symport</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="414" mass="44971" checksum="EC22566F4CBD0792" modified="2008-04-29" version="1">MDPQVLEPQLLEIKDFVSFTLAIIALFIGKAIISRYELLRKYSIPEPVVGGFACASIVGILYYGFDLQIEFNLDVRDILLLYFFAGIGLKADFATLIKGGKPLLILITLSTLFIFMQNFMGVSVASLFGLDPKAGLMSGSISLIGGVGTAMAWTPTFVEELGIANANELGIASNTLGLISACVIGGPIAAYLMKRHHIKANQDDSLDIGASHKTSSQHIRVDYFGVLRAWLWLNVTLIIGYFIDIALQELGLKLPMFVACLLAGIIIGNSGRALLNRSKDKGEAYLKDASQGLSLIQDICLGMFLTMALMSLKIWELEGSLFYISVVMSLQVLLSIIFTVFIVFRMMGKDYEAAVICSGFGGVTLGSTATAIVNMTAVTQQYGAAHRAFIIVPLVCGFFIDIINAMIINLFAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJU0</accession>
    <name>B1KJU0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325463.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2852"/>
    <dbReference type="EnsemblBacteria" id="ACA87127">
        <property type="protein sequence ID" value="ACA87127"/>
        <property type="gene ID" value="Swoo_2852"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2852"/>
    <dbReference type="eggNOG" id="COG4922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073327_1_0_6"/>
    <dbReference type="OMA" id="FEVFRFE"/>
    <dbReference type="OrthoDB" id="1598464at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="29201" checksum="FA375ED39DFD0355" modified="2008-04-29" version="1">MTSRRKQLIHALLKGIETGDPESVKVVNQSQYIQHNPQTHEGDEGLAALFKRLSKTSPRVNIVRIFADADFVFAHTEYDFSSQRVGFEMFRFEGDQTVEHWDNIQSRQGPNSAGHSMVDGIAEVSDLDKTESNRELVQSFVNEVLISRQLNKLSHYIDIDHYIEHNPKLSSLSSVHVALSESDIDDRFSIQYDKSHRILAEGNFVLSACEGYYQGQHSSFYDLFRLESGKIIEHWDTRETIHPKSEWKNNNGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK36</accession>
    <name>B1KK36_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326993.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4415"/>
    <dbReference type="EnsemblBacteria" id="ACA88667">
        <property type="protein sequence ID" value="ACA88667"/>
        <property type="gene ID" value="Swoo_4415"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4415"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053124_0_0_6"/>
    <dbReference type="OMA" id="WWMGLAY"/>
    <dbReference type="OrthoDB" id="1438690at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011716">
        <property type="entry name" value="TPR-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07720">
        <property type="entry name" value="TPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="397" mass="43835" checksum="1039DD1C0F6D7A08" modified="2008-04-29" version="1">MSVINTMLKDLDKRQQPHSLENMSTAPVQYQGSSAPKMPWILLALVCFIFLTAVAYNWELLTQKSASEAGGGTSSEAQELVIRQALEAKAPSTVTSTHSTVDVQEIAEDKLEPVIASEGSTKSEVISKSQVVEQIKIEKQPVEKAVIDEPTAETVAIESKPSDGAEQVSAKPESIEVVRSKPVTPKVDNSSMAITEVRLSNAQLAEKRFQAATNAEDSGEQRDAIEYYREALAFSPQLHKARQRLAALFYGQGNLAQASDTLQEGSSLFPEQYEYLMLLARVQQAAGGYEQALTSLNRIPDGTALNKQKWTQESSIAQKVKNYGLAESSYRKLLQTEATMSRWWMGLAYALDAQQKYETAIEAYRQALFYRAVPQQGLSVQAVDYIENRLVQLGESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK84</accession>
    <name>B1KK84_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327041.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4463"/>
    <dbReference type="EnsemblBacteria" id="ACA88715">
        <property type="protein sequence ID" value="ACA88715"/>
        <property type="gene ID" value="Swoo_4463"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4463"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_22_2_6"/>
    <dbReference type="OMA" id="REFIMTC"/>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16423" checksum="89A7E2DF5F5F1A89" modified="2008-04-29" version="1">MGYTLRKAKESDLEYLLQLRRLTMDDYLSQNGVDISDKEHLFRIKFNFSDAKIILVNGVKAGLFKASYTASNSQWYIYQVQIHPNYQGLGIGSKIILDLCQQALTNDLSVGLSVLKSNPAKSLYERLGFSVTSSTNCEYEMVYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKE3</accession>
    <name>B1KKE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-ECFsigma factor, ChrR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324129.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1495"/>
    <dbReference type="EnsemblBacteria" id="ACA85783">
        <property type="protein sequence ID" value="ACA85783"/>
        <property type="gene ID" value="Swoo_1495"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1495"/>
    <dbReference type="eggNOG" id="COG3806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111523_0_0_6"/>
    <dbReference type="OMA" id="IWVKTGH"/>
    <dbReference type="OrthoDB" id="1792151at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025979">
        <property type="entry name" value="ChrR-like_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12973">
        <property type="entry name" value="Cupin_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="132"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="25149" checksum="1CB9790519EAD890" modified="2008-04-29" version="1">MQQLKSNLNMDFSKKVMIDTNQLEWLPSPLKGVTRKPLAREDLESGHATSIVKYQAGSHFKRHSHPQGEEILVLEGVFSDETGDFGPGTYIRNPPGSSHRPFSTDGCTLFVKLNQFDKNDLQQVRVDTHSTPWQRGMGGLEVMSLHDFEGQHTALVKWPADEVFQPHRHFGGEEILVLSGLFEDEHGQYPANTWIRSPHMSQHHPFVKEETIILVKVGHLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKM2</accession>
    <name>B1KKM2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325575.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2968"/>
    <dbReference type="EnsemblBacteria" id="ACA87239">
        <property type="protein sequence ID" value="ACA87239"/>
        <property type="gene ID" value="Swoo_2968"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2968"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066933_0_0_6"/>
    <dbReference type="OMA" id="PMYHLDK"/>
    <dbReference type="OrthoDB" id="1152952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="74"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="31865" checksum="6903622906E73DCC" modified="2008-04-29" version="1">MLKKLFGIAPTLELDGSYSPSKLALKLATSDKTDFENVTYSKYQGSKTKILAIFTEQKNMTMHNGKLFSTGNHPVEALVPMLHLKNAGFEFEIVTPTGKPVVFEMWAFPEKDEHVKAFYNKYKSNFEQPKSLDEVVKNVIDTPSIKTVTASYAAVFVPGGHGAMLGIPEDINVGKVLNWAHENDLFTVTLCHGPASLLATTLDGQRFLYQGYKMAVFPDSVDKMTPKVGYLPGQMTWGLSEKIQSLGVNIVNKKSDNTVCLDRKLITGASPLASDALGKLAAETLLKELQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKX7</accession>
    <name>MURG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="1">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">murG</name>
        <name type="ordered locus">Swoo_4533</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327109.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKX7"/>
    <dbReference type="SMR" id="B1KKX7"/>
    <dbReference type="STRING" id="392500.Swoo_4533"/>
    <dbReference type="CAZy" id="GT28">
        <property type="family name" value="Glycosyltransferase Family 28"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88783">
        <property type="protein sequence ID" value="ACA88783"/>
        <property type="gene ID" value="Swoo_4533"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4533"/>
    <dbReference type="eggNOG" id="COG0707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037404_2_0_6"/>
    <dbReference type="OMA" id="AADMMLC"/>
    <dbReference type="OrthoDB" id="1165736at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000090473" description="UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="17"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="269"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <sequence length="365" mass="39057" checksum="7BA8594E9C068189" modified="2008-04-29" version="1">MTNVSDEKRILIMAGGTGGHVFPALAVAKYLSKQGWKVRWLGTAERMEARLVPQHGFDIDFIDIKGVRGNGVVRKLAAPFKVLRSITQARVVIKEFQPDVVLGMGGFASGPGGVAARLSGIPLVLHEQNAIPGMTNKILSRIASQVLCAFEDTFDQVQAEVVGNPIREELIALGQTPKDAGAKESLKVLVVGGSLGAKVFNDLMPTVTADMSKTHLITVWHQVGKGNLQSVKGEYQRLGLDGSVSVAEFIDDMEAAYRWADVVLCRSGALTVSELAAIGLPSLLVPYPHAVDDHQTKNAQVLVKAGGAFLLPQPILDIDKLIGKLQILSSDRDELDQMGQRAKSVGVIDATQKVADVCIRLAGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP5</accession>
    <name>B1KLP5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PpiC-type peptidyl-prolyl cis-trans isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325678.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3071"/>
    <dbReference type="EnsemblBacteria" id="ACA87342">
        <property type="protein sequence ID" value="ACA87342"/>
        <property type="gene ID" value="Swoo_3071"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3071"/>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090028_6_1_6"/>
    <dbReference type="OMA" id="ASEDKCN"/>
    <dbReference type="OrthoDB" id="1838755at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="92" mass="9691" checksum="13800C8FC7AA50F3" modified="2008-04-29" version="1">MVQATARHLLVSSEEKCEALKQEIMGGADFADVAKANSSCPSGAQGGDLGSFGPGMMVKEFDEVVFSAPLNEVQGPVKTQFGYHLLEVTSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLR5</accession>
    <name>B1KLR5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325698.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87362">
        <property type="protein sequence ID" value="ACA87362"/>
        <property type="gene ID" value="Swoo_3091"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3091"/>
    <dbReference type="HOGENOM" id="CLU_2131838_0_0_6"/>
    <dbReference type="OrthoDB" id="2162929at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="12280" checksum="E478D0CDEF498234" modified="2008-04-29" version="1">MDRVIGGDVINIEAPQDRQYLKFVVRVSSCDFDSINVRFYNSNGSAIKIDFSELRIGLVWNSETDVTTLGEFEEVNKFEEGFVILGDFGTIYVYCDQCSPSLNTLITSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLX5</accession>
    <name>B1KLX5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Patched family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327180.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4605"/>
    <dbReference type="EnsemblBacteria" id="ACA88855">
        <property type="protein sequence ID" value="ACA88855"/>
        <property type="gene ID" value="Swoo_4605"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4605"/>
    <dbReference type="eggNOG" id="COG4258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017576_0_0_6"/>
    <dbReference type="OMA" id="HVMTLVL"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="662"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="686"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="714"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="744"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="770"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="271"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="799" mass="86958" checksum="92F506D7866603D0" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLZ3</accession>
    <name>B1KLZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4623</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327198.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4623"/>
    <dbReference type="EnsemblBacteria" id="ACA88873">
        <property type="protein sequence ID" value="ACA88873"/>
        <property type="gene ID" value="Swoo_4623"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4623"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_414967_0_0_6"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="SSF49363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767196" evidence="2">
        <location>
            <begin position="22"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="144"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PPC" evidence="4">
        <location>
            <begin position="471"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="PPC" evidence="4">
        <location>
            <begin position="580"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="658" mass="71087" checksum="6BD164C003296EC9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KML3</accession>
    <name>B1KML3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP dicarboxylate transporter, DctP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324357.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1726"/>
    <dbReference type="EnsemblBacteria" id="ACA86011">
        <property type="protein sequence ID" value="ACA86011"/>
        <property type="gene ID" value="Swoo_1726"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1726"/>
    <dbReference type="eggNOG" id="COG1638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_1_3_6"/>
    <dbReference type="OMA" id="AFWHNGM"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004682">
        <property type="entry name" value="TRAP_DctP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006470">
        <property type="entry name" value="DctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00787">
        <property type="entry name" value="dctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767211" evidence="2">
        <location>
            <begin position="39"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="344" mass="38446" checksum="6DE1016230B2F877" modified="2008-04-29" version="1" precursor="true">MTNRYLPAQLQSLARSIKAFVKLSTITTMLVSSSQVFAAPVEIKFSHVVAENTPKGQMALKFKELVELRLPGEYQVNVFPNSQLFGDNNEVAALLLNDVQFVAPSLSKFERYTKKLQIFDLPFLFSDMEAVNRFQQGESGQKLLGSMKRKGIVGLGYLHNGMKQLSASSPLILPTDASGKKFRIMASDVLAAQFQAIDAIPVKKPFSEVFTLLQTRAIDGQENTWSNIYSKKFYEVQSYITESNHGVLDYMVVTSNTFWKSLPADKRTIIKTALDEAVAYGNEIAAAKVNKDKETIVASKRSEVIQLSPEQRQQWVTSMKPVWSQFEAKIGKNLIQAAEASNKQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMW5</accession>
    <name>RL30_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmD</name>
        <name type="ordered locus">Swoo_4672</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327245.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMW5"/>
    <dbReference type="SMR" id="B1KMW5"/>
    <dbReference type="STRING" id="392500.Swoo_4672"/>
    <dbReference type="EnsemblBacteria" id="ACA88922">
        <property type="protein sequence ID" value="ACA88922"/>
        <property type="gene ID" value="Swoo_4672"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4672"/>
    <dbReference type="eggNOG" id="COG1841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131047_1_4_6"/>
    <dbReference type="OMA" id="GKQNQRD"/>
    <dbReference type="OrthoDB" id="2084745at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_L30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="PTHR15892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000144719" description="50S ribosomal protein L30">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01371"/>
        </source>
    </evidence>
    <sequence length="60" mass="6768" checksum="39E723A294BC37EA" modified="2008-04-29" version="1">MATKTIKVTQTKSSIGRLPKHRASLLGLGLRRINHTVEVEDTPSVRGMINKVYYMVKVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN34</accession>
    <name>B1KN34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327308.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4741"/>
    <dbReference type="EnsemblBacteria" id="ACA88991">
        <property type="protein sequence ID" value="ACA88991"/>
        <property type="gene ID" value="Swoo_4741"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4741"/>
    <dbReference type="eggNOG" id="COG2329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114411_0_0_6"/>
    <dbReference type="OMA" id="WNPAMAG"/>
    <dbReference type="OrthoDB" id="1675553at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032555">
        <property type="entry name" value="DUF4937"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16291">
        <property type="entry name" value="DUF4937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4937" evidence="2">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="111"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="23933" checksum="8EE91AC50C683FA2" modified="2008-04-29" version="1">MIAKYIRCEVVEAKRNIFSKGQRLWLETAHCEGFISQLGGWEQETNIAVILARWTDMESVKDFMSAAHDPIAERANQVGSYSHISVSYLSAVICIPAFNQGGKNQASCGFIRIADCYIDPDKLDEFIQEQKTLWNPGMQQVEGMLGGQLWQFNDESDRYLVTTYWESEAAHRHYMAEYFPRLKQQAATDIIHTISGHHIQTEPSWRVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN47</accession>
    <name>B1KN47_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327321.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4755"/>
    <dbReference type="EnsemblBacteria" id="ACA89004">
        <property type="protein sequence ID" value="ACA89004"/>
        <property type="gene ID" value="Swoo_4755"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4755"/>
    <dbReference type="eggNOG" id="COG3303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017567_0_0_6"/>
    <dbReference type="OMA" id="WPNTGIG"/>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023155">
        <property type="entry name" value="Cyt_c-552/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13435">
        <property type="entry name" value="Cytochrome_C554"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767514" evidence="1">
        <location>
            <begin position="32"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_C554" evidence="2">
        <location>
            <begin position="29"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_C554" evidence="2">
        <location>
            <begin position="108"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="488" mass="54911" checksum="7E6887BC3614B70E" modified="2008-04-29" version="1" precursor="true">MEYARNVRRCLSILLPLIAVVSLSWTSTANAEAKALVLKPFKQLSDESSECAACHKEKNPSIYAQWGRSKHYGANVGCYECHAADKGDKDAIKHEGRLISVIVSPKDCAQCHNQEVEEFTKSHHAKAGKIMGSLDNFLAEVVEGAMTFNGKSPAAVNGCWQCHGSEVKVLPNGDLDPTTWPNTGIGRINPDGSIGACTACHQRHEFSMTQARRPEACGKCHLGPDHPQKEVYDESKHGINFYANVDRMNLDSSKWIVGEDYDAAPTCATCHMSATREQAVTHDVGDRISWTLRPAVSEKIDAKAIAQGHKVKSWQDRRADMQDVCQSCHTKSMTDSFYQQFDSLVNLYNDKFASPGKRLMGMLKEQKMLTETAFDEEIEWTWFFLWHHEGRRARHGAAMQAPDYVQWHGMFEVAERFYIEMVPQYLEVVEKAEHEGNTQGAEKARKLLDEILARPEHAWFTGNEPDEVKAARKAAQKEFKARYLSESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN49</accession>
    <name>B1KN49_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein TonB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0245</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell inner membrane</location>
            <topology evidence="1 9">Single-pass membrane protein</topology>
            <orientation evidence="1 9">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322895.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0245"/>
    <dbReference type="EnsemblBacteria" id="ACA84546">
        <property type="protein sequence ID" value="ACA84546"/>
        <property type="gene ID" value="Swoo_0245"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0245"/>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108529_1_0_6"/>
    <dbReference type="OMA" id="NWKYKPK"/>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031992">
        <property type="term" value="F:energy transducer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003538">
        <property type="entry name" value="TonB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01374">
        <property type="entry name" value="TONBPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="121"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="22675" checksum="2427832B870B0E21" modified="2008-04-29" version="1" precursor="true">MISISLLRRTSIALVAAVITLSLFAFMAKLIDAEHPQQIETVQVPEFEIAPIIKDKEPIKKQIELKPKEELVEPTIPQRTVSGTDTGITAQTIETIKMPTLSTEYNRDSMTSEALPIVQVSPRYPIIAAQNGKEGYVILGFDITKMGTVTNVKVLEANPKRIFNKAAIQAIKNWKYKPKMEKGVAVIQSNQQVQLDFTLEQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN67</accession>
    <name>B1KN67_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322913.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0263"/>
    <dbReference type="EnsemblBacteria" id="ACA84564">
        <property type="protein sequence ID" value="ACA84564"/>
        <property type="gene ID" value="Swoo_0263"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0263"/>
    <dbReference type="eggNOG" id="ENOG5032CBR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1546561_0_0_6"/>
    <dbReference type="OMA" id="VNGFCSH"/>
    <dbReference type="OrthoDB" id="1577250at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767230" evidence="1">
        <location>
            <begin position="25"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="173" mass="20009" checksum="2B1EEF3744F24EAC" modified="2008-04-29" version="1" precursor="true">MILSCSKYGLLYCLFLCFPITSWAERANFSEFCSALDGQWQGSSAKSKQKPVQTKINANCSDDRRQLILTVNPSAKHPLSETWWFRARGEAISLIYFDGVDEDKSQLFSLYHHQGSYSLLGEGELNSRPAMIQLRFDQKEVGWLWLQNIQYLDDDTDRYLFYRGIEMLPAAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN75</accession>
    <name>B1KN75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0271"/>
    <dbReference type="EnsemblBacteria" id="ACA84572">
        <property type="protein sequence ID" value="ACA84572"/>
        <property type="gene ID" value="Swoo_0271"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0271"/>
    <dbReference type="eggNOG" id="COG1328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046504_1_0_6"/>
    <dbReference type="OMA" id="TIIYHHV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016905">
        <property type="entry name" value="Glycyl_radical_YjjI-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11230">
        <property type="entry name" value="DUF3029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028991">
        <property type="entry name" value="Glycl_rad_HI0521_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04040">
        <property type="entry name" value="glycyl_YjjI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="523" mass="57900" checksum="56B387214C68BF8E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNG1</accession>
    <name>B1KNG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324384.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1753"/>
    <dbReference type="EnsemblBacteria" id="ACA86038">
        <property type="protein sequence ID" value="ACA86038"/>
        <property type="gene ID" value="Swoo_1753"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1753"/>
    <dbReference type="eggNOG" id="COG3124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099370_1_0_6"/>
    <dbReference type="OMA" id="MNFLAHI"/>
    <dbReference type="OrthoDB" id="1398998at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008770">
        <property type="term" value="F:[acyl-carrier-protein] phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009079">
        <property type="entry name" value="4_helix_cytokine-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007431">
        <property type="entry name" value="ACP_PD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38764">
        <property type="entry name" value="PTHR38764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04336">
        <property type="entry name" value="ACP_PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011489">
        <property type="entry name" value="DUF479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47266">
        <property type="entry name" value="SSF47266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="200" mass="22955" checksum="E38F9829C4125F36" modified="2008-04-29" version="1">MNFLAHLHLADNSNTSLAANLAGDFAKGNIADFPKHLQQGIWLHRQIDQLTDSHEITKELLTKFPVSLRRAAPILIDLAFDHMLAKYWDEYHSASLKAFSTIAYDAIDACEQLPERLQLIAPKIRSENWLLAYRDRKGLNKAIESMARRVSKPEIFNGATKAVSDLDIEIEIAFRTFYPQLMAYSRIWTRKTPSEYLHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNJ1</accession>
    <name>B1KNJ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1784</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324414.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1784"/>
    <dbReference type="EnsemblBacteria" id="ACA86068">
        <property type="protein sequence ID" value="ACA86068"/>
        <property type="gene ID" value="Swoo_1784"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1784"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_0_6"/>
    <dbReference type="OMA" id="MYSKRWS"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767239" evidence="5">
        <location>
            <begin position="32"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="55"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="376"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="873" mass="94520" checksum="44167D7F0F7E7018" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL7</accession>
    <name>B1KNL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324440.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1810"/>
    <dbReference type="EnsemblBacteria" id="ACA86094">
        <property type="protein sequence ID" value="ACA86094"/>
        <property type="gene ID" value="Swoo_1810"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1810"/>
    <dbReference type="eggNOG" id="ENOG5032UIH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072067_0_0_6"/>
    <dbReference type="OMA" id="LLHMTWQ"/>
    <dbReference type="OrthoDB" id="1767993at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021241">
        <property type="entry name" value="CsiV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10972">
        <property type="entry name" value="CsiV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764691" evidence="1">
        <location>
            <begin position="21"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="312" mass="35481" checksum="592B8D566F38BF44" modified="2008-04-29" version="1" precursor="true">MLKKTLLPLMGLLSITQAYAQDERWFEVEVYLFERDAGHNQEKSPDQVTLINTRKAVDLISPLFSTDITGASLGLKGCSSSDWATNADECNQQLGSAQVNHTTQIPVNIAAATEQYGIPGGAPVLLSSEQNQFKDIMSKISREPGNKSLLHMTWQQSMLPRHKAKPMRLYSGQDFSDRFEGNGQMVQSYQSELTIPQFDFLDTSFDSKTQKPVWELDGTLNIYLNHYLYVEAALNLREEGTKEIDTSSSYLNETVEQSNKVTPFLYAFPLTQNRRVRSDEIHYFDHPKMGMILQIRKMEQPTDRIKDIANEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ7</accession>
    <name>B1KNQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325851.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3245"/>
    <dbReference type="EnsemblBacteria" id="ACA87515">
        <property type="protein sequence ID" value="ACA87515"/>
        <property type="gene ID" value="Swoo_3245"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3245"/>
    <dbReference type="HOGENOM" id="CLU_2525704_0_0_6"/>
    <dbReference type="OrthoDB" id="2043173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="84" mass="9848" checksum="E77BEDC330D1CFDB" modified="2008-04-29" version="1">MGQEKTNGFMEEPDIAIEEIKWYRWRWFLILTFCFVYPVCLVIGLTGNVYGKHQGVVFKLPNKVKHLFLITGFVLMLGNILRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX2</accession>
    <name>B1KNX2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3311</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325916.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3311"/>
    <dbReference type="EnsemblBacteria" id="ACA87580">
        <property type="protein sequence ID" value="ACA87580"/>
        <property type="gene ID" value="Swoo_3311"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3311"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_6"/>
    <dbReference type="OMA" id="WHASTQG"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="196"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="32403" checksum="B8C9633341284DFB" modified="2008-04-29" version="1">MSALNGLLSSFHLNATIFHRSLVCDPWSTDTSGSGLASFHLISSGKAFLFCDDYQAEPLTAGDLVIFPHDSPHIISHSPDKQTAKETDGFVAYPFSDNTPHSAGLMCGYFDFKEDSSHPVIAQLPSCILIKSQQNQGVLASIIESLILEVTLGAQASDIILSRLCEVFFLSLLRQLSAEDNSQMGLFRALQDTKMAKVLQAIDSNLAAPWDLNSLANVGGYSRASFINHFKNYLDTTPQEYLSQLRLTKAKKQLIRGDAVLKVALDVGYSNDVSFAKAFKRYFGYGPGVCRANSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX5</accession>
    <name>B1KNX5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327323.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4757"/>
    <dbReference type="EnsemblBacteria" id="ACA89006">
        <property type="protein sequence ID" value="ACA89006"/>
        <property type="gene ID" value="Swoo_4757"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4757"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066015_1_0_6"/>
    <dbReference type="OMA" id="RCDYFPR"/>
    <dbReference type="OrthoDB" id="1643157at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="295" mass="33778" checksum="CFA2E1F7BC18260C" modified="2008-04-29" version="1" precursor="true">MRIVLGLAVLLYAHLTWSAEALLIQSPQSEDDASYHYYVDLIFEVLKETQGEYGVAKLVETGSSYTQNRGLNALESDQLTIFWAGTDPKREKRYHVIRIPLMAGLLGMRVPVVHRSQYQKFLALESAEQLKQLTACQGTHWPDSYVLEQNGYRVERVTKFESMYSMLRQGRCDYFPRGIGEVHAELEHSMNQDMVAVDNLLLTYPMPMYVFLNKRNMQLAKRLEQGLNAMVERGDIFEFVRQHPATRGVFPLGKYHQAKLARLTNPLLSNSTELDNPLFWLQLSPTSEGGVLESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP24</accession>
    <name>B1KP24_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coproporphyrinogen dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.98.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.98.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327372.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4806"/>
    <dbReference type="EnsemblBacteria" id="ACA89055">
        <property type="protein sequence ID" value="ACA89055"/>
        <property type="gene ID" value="Swoo_4806"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4806"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027579_3_1_6"/>
    <dbReference type="OMA" id="CHTLCSF"/>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="55"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="445" mass="50991" checksum="6D75AE5B7385D4E4" modified="2008-04-29" version="1">MSSIIQSAGSEIIKPYQADITVPNWMLSSMERVMQFYVDRNLRLDTQSADMMPAPVEGKKYMLYAHVPFCHTLCSFCTFHRFLFKEDKARAYFISLRKEMDMVKALGYDFESMYIGGGTTTVLEDELARTIEHAKTLFPNIKEVSCESDPQHLDSPEFKQLEGLVDRMSIGVQSFNDDILAMTDRLDKFGSGQQTFDKIMAAKELFPIINVDLIFGFRGQTDEIIQHDLDMASKLDPRQITTYPLMITHQTRKSVKGKLAASQGDMARQYRQILNSLNGQYNQLSAWAFGKANNEGFDEYVIDYDEYLGVGSGSFSFLDDTLYVNNFSLRKYHENINAGRMGVEQQKNYSKKDVMQYRFLLGMFSGRLSRKYFRETFGVNLDTALFKEMTSMKVIGAIKNDPTDPDKLIVTDNGKMMGLLMMKEFYSGMDNVRAQLRKPLKPCDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP63</accession>
    <name>B1KP63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327411.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4845"/>
    <dbReference type="ESTHER" id="shewm-b1kp63">
        <property type="family name" value="A85-IroE-IroD-Fes-Yiel"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89094">
        <property type="protein sequence ID" value="ACA89094"/>
        <property type="gene ID" value="Swoo_4845"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4845"/>
    <dbReference type="eggNOG" id="COG2819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_700000_0_0_6"/>
    <dbReference type="OMA" id="DWMSHNG"/>
    <dbReference type="OrthoDB" id="1828423at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765098" evidence="1">
        <location>
            <begin position="25"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="395" mass="44545" checksum="6E0BF42420C39362" modified="2008-04-29" version="1" precursor="true">MLKTLMFSLSLLFVLVLNIASVNAQSSAGQELITTLDVATSYSDKPITFNVTLPPSYFNNKDKRYLVLFDFHPRSQAYLNGMHDWMSHNGDWPWLETIIVTAPDGDKTLGELKELAIEERGDTKLLDFMELALLPTIDKQYRTNGFRIMNGFTGNAGLGLYTLLNRPELFNAYFVASPVLSKDFAFVIKDAPKKLAAMKGKPRFLFMSTSDSGFEQRQLASFAEMETIIKATASPALEYHIKRFDGSYYMTQPILATAYGIELLFNDYHKMLEPDSEISSKGPQAILAHYQYLTDEKYGFEVPATASLIALAKYEADKGGKTAKNKAIAIYQVAVDAYPHSHTAHHALAQAYAEVGEFERAVTHEKLALKNTDHPFWRNKYTERLVELEVRKKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP89</accession>
    <name>B1KP89_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323008.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0359"/>
    <dbReference type="EnsemblBacteria" id="ACA84659">
        <property type="protein sequence ID" value="ACA84659"/>
        <property type="gene ID" value="Swoo_0359"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0359"/>
    <dbReference type="eggNOG" id="ENOG5031PN4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_539568_0_0_6"/>
    <dbReference type="OrthoDB" id="92173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764715" evidence="1">
        <location>
            <begin position="19"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="502" mass="56835" checksum="0678734A18820C56" modified="2008-04-29" version="1" precursor="true">MKLSVTLFAVILILSACSDNHNKDAVEFKANVGDSAKYWVQHVSRIDLATATIGESTTLSLLRYRIEQTDATTLRFSVIPEYFQNTPYCENQFRRLQTKVAKYCALVWEGFKLDLNPADGSLINLQRTSASGWQTMLDKGTSLLVKSLRNTVNAPGFIQTIPKIIGSKITLHDFSGFTLTMIVDKVTSQTIELSFTRDDPQFRQYGKVIVNQSNGWLQHATLIAEKPLGSYQTAYRRTVMQKTNEYDAPGLITVIKDHRRVESNWTDISQTAKYHAAQDAPIDKSFFQFSQARMQQWGEIIDTDLKISDEKQQPQGEVRFENLRGQSTIDPELNIKFSPRFNPMISSTEQGVYANMRLMALTSARLSSLNLIDSITAEMVYYPAKIESHTLPWPSNKPKTYSLGQAQLEITPVPNKSNIYEVTYISANDDYLLPVFGGVEGQFSRLPPKVGPQWLGLGDRPLVPTNQMSWQLKVDNPPEHVTVYIKNVSKKATQKHSVVWYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPN2</accession>
    <name>B1KPN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secretion protein HlyD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324531.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1901"/>
    <dbReference type="EnsemblBacteria" id="ACA86185">
        <property type="protein sequence ID" value="ACA86185"/>
        <property type="gene ID" value="Swoo_1901"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1901"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_711504_0_0_6"/>
    <dbReference type="OMA" id="RRVWQYQ"/>
    <dbReference type="OrthoDB" id="1532186at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764725" evidence="1">
        <location>
            <begin position="32"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="154"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="403" mass="44410" checksum="110B5690FEA6B712" modified="2008-04-29" version="1" precursor="true">MKKTVNSIARKTWIKSFVLSSLTLSSASMLSACNHESVTRVEQGVLSQSIEASGELVSADTVSLMPPSIRRVWQYQVKQLAQEGAEVQQGDMVAQLDTSALTQKLSVKTAKLEATLQDIETSKLRNAKKLEELRLGLAEDKMNLEKAERKFRLSDETVAAIEKFKYQKDAEIARDKVNLTEQKLVLEVKGAKQREAMLMGDRQKFAAEVEQLKRGIQSLTLIAPRSGMVVYCNDSQGNKIKEGQSVFMGDAVLSIPDLTHMQVNMTIPEVEARRVKIGQELKIRLDANPDKVFTGNIIELGAVFRNKNQEVPLVVFDAVASIDEADTELMRPGMTAKISIDIANEKQELLLSLDAVHYDAGQAYVFTPDTFSNSKQAVTIGAIGKERVSITSGLALGQEVVLP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ33</accession>
    <name>ATPE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpC</name>
        <name type="ordered locus">Swoo_4897</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327463.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ33"/>
    <dbReference type="SMR" id="B1KQ33"/>
    <dbReference type="STRING" id="392500.Swoo_4897"/>
    <dbReference type="EnsemblBacteria" id="ACA89146">
        <property type="protein sequence ID" value="ACA89146"/>
        <property type="gene ID" value="Swoo_4897"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4897"/>
    <dbReference type="eggNOG" id="COG0355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084338_2_0_6"/>
    <dbReference type="OMA" id="MGGFAEI"/>
    <dbReference type="OrthoDB" id="1696893at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036794">
        <property type="entry name" value="ATP_F1_dsu/esu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020547">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00401">
        <property type="entry name" value="ATP-synt_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46604">
        <property type="entry name" value="SSF46604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0139">CF(1)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000127891" description="ATP synthase epsilon chain">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <sequence length="142" mass="14964" checksum="CFD2C88CEBCE142B" modified="2008-04-29" version="1">MAAMTVQLDIVSAENSIFSGLVAHLQVTGSEGDLGVMPGHAPLLTNIKPGMARIVKQDGKEEVFYLSGGILEVQPSSVSVLADVVKRADEIDEKAAEEAKRRAESAMADAGADFNYAAAANELAQAVAQLRVVDTIKKNIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ56</accession>
    <name>B1KQ56_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327485.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89169">
        <property type="protein sequence ID" value="ACA89169"/>
        <property type="gene ID" value="Swoo_4920"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4920"/>
    <dbReference type="eggNOG" id="ENOG502ZXQR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121473_0_0_6"/>
    <dbReference type="OMA" id="FSTHEHR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021316">
        <property type="entry name" value="DUF2913"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11140">
        <property type="entry name" value="DUF2913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="21938" checksum="CF627BA7C14D853C" modified="2008-04-29" version="1">MIISNIFQVFTDNAILHLYLELSDRGGFSTHEHRNQILVRFIKKSLKNQKYKIIRKELKRLLHVRGNTSISLESRLWDFKIVSDKSKSDLRHLYDLLEYLNLDLGLESRFFIDEPDEKFISMKQYEVENCFNKKGEQLTPISMTIETAKLDKVIDYISQKSPFTVEIASSSSKCFFIVIYLFLNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA6</accession>
    <name>B1KQA6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane CreD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323110.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0463"/>
    <dbReference type="EnsemblBacteria" id="ACA84761">
        <property type="protein sequence ID" value="ACA84761"/>
        <property type="gene ID" value="Swoo_0463"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0463"/>
    <dbReference type="eggNOG" id="COG4452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036281_1_0_6"/>
    <dbReference type="OMA" id="RVHPIQY"/>
    <dbReference type="OrthoDB" id="296258at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010364">
        <property type="entry name" value="Uncharacterised_IM_CreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30092">
        <property type="entry name" value="PTHR30092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06123">
        <property type="entry name" value="CreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004548">
        <property type="entry name" value="CreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="448" mass="49975" checksum="924B2D1362A95ADB" modified="2008-04-29" version="1">MLNLFTTAASNITHKIIILVGISLLSSIPLGIVMNMTSDRQYLYNDVVNEIGQSWGPQQRISGPALVIPYRYHMVHEKINDAGELVKYKSEYQSELVILPKKLKLNMDLKHDFRSRGIYQSLVYNAAVSGKAKFVMTELDIPNLIELKTDNARLIFGISANQAIEKIERLTLLNSDGKVLLTQAEAGVMPGTGLDRQLGLERGFHQPLSINLQQDDFEVDFAIALRGSQSISALPLGEHTDIAITTDWPHPSFNGILPTNREISDTGFSADWKISHLTRNYPQVFSSHQDINLTEVQASSQLFEPVTHYGKIERSVKYGMLFIALTFIVLLIFEFGQNTRLNLVQYLLVGCAVTLFYLLLLSLSEHLEFNYAYTIAASIPVLSVSAYVASATASYKKGAIIATMLTSLYGVLYSILKLEDYALLMGTGLLLTVLLILMFITRHKSMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB4</accession>
    <name>B1KQB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0471</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323118.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0471"/>
    <dbReference type="EnsemblBacteria" id="ACA84769">
        <property type="protein sequence ID" value="ACA84769"/>
        <property type="gene ID" value="Swoo_0471"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0471"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_109_1_6"/>
    <dbReference type="OMA" id="LPNRQYM"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032244">
        <property type="entry name" value="LapD_MoxY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042461">
        <property type="entry name" value="LapD_MoxY_peri_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16448">
        <property type="entry name" value="LapD_MoxY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="172"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="263"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="403"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="640" mass="73109" checksum="F766336FBBE0E28B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH6</accession>
    <name>B1KQH6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1931</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324561.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1931"/>
    <dbReference type="EnsemblBacteria" id="ACA86215">
        <property type="protein sequence ID" value="ACA86215"/>
        <property type="gene ID" value="Swoo_1931"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1931"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_2_0_6"/>
    <dbReference type="OMA" id="GIQMWRS"/>
    <dbReference type="OrthoDB" id="1440181at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="205" mass="22366" checksum="34975D304479F843" modified="2008-04-29" version="1" precursor="true">MPDFALLAVFLPTFFFVSITPGMCMTLAMTLGMSIGVRRTLWMMIGELVGVALVAIAAVMGVASIMLNYPQIFEVLKWVGGIYLAYIGVQMWRAKGKMAKLDEQSARISNSTLISQGFITAIANPKGWAFMISLLPPFINVDKELAPQFVALLSIILFTELISMLAYAAGGKSLKIFLSRGDNIKWMNRIAGSLMIGVGFWLALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI8</accession>
    <name>B1KQI8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1943</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324573.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1943"/>
    <dbReference type="EnsemblBacteria" id="ACA86227">
        <property type="protein sequence ID" value="ACA86227"/>
        <property type="gene ID" value="Swoo_1943"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1943"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015233_0_0_6"/>
    <dbReference type="OMA" id="SRRDKFW"/>
    <dbReference type="OrthoDB" id="1597438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006686">
        <property type="entry name" value="MscS_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045042">
        <property type="entry name" value="YnaI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43634">
        <property type="entry name" value="PTHR43634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01246">
        <property type="entry name" value="UPF0003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767298" evidence="8">
        <location>
            <begin position="24"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="533" mass="59301" checksum="5A70DECDDC4BFAC9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI9</accession>
    <name>B1KQI9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated CheW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1944</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324574.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1944"/>
    <dbReference type="EnsemblBacteria" id="ACA86228">
        <property type="protein sequence ID" value="ACA86228"/>
        <property type="gene ID" value="Swoo_1944"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1944"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048995_0_0_6"/>
    <dbReference type="OMA" id="YLAFPNG"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024181">
        <property type="entry name" value="Chemotax_regulator_CheV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002867">
        <property type="entry name" value="CheV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="3">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="184"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="314" mass="35205" checksum="1128681D5DED296A" modified="2008-04-29" version="1">MTKVLDSVDQRTQLVGENRLELLLFRINATQLFAINVFKVKEVVKLPPLNSVPGSHPHISGVANIRGSSIPVIDLRGAIGFSPMSSDQERNLIITEYNRSIQGFMVGKVEHIVNMTWSDILPPPKTAGKQNYLTAICRLEIDDVINMVSIIDVEKVLAEIINYDIRLSEGVLDEELAKEMVGRRILIADDSSTARRQIKETLEPLGIEILEVSDGLQALQLLQSWCNEGKSIYDEILMLITDAEMPEMDGYKLTSEIRSDNRMSDLFIALNTSLSGSFNEAMVEKVGCDRFISKFQPDLLVGVVQDKLREQKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQK1</accession>
    <name>B1KQK1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1956</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324586.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1956"/>
    <dbReference type="EnsemblBacteria" id="ACA86240">
        <property type="protein sequence ID" value="ACA86240"/>
        <property type="gene ID" value="Swoo_1956"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1956"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_47_0_6"/>
    <dbReference type="OMA" id="YFFMLNI"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="14"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="43644" checksum="93842531F4702C80" modified="2008-04-29" version="1">MQTDPQQSPATVTPVAIVNLAILIPMLAAIVAITPLAIDMYLPAMATLASSFHSDITTVQQSLSIYLAGYAVGMLCFGPLADRIGRRPLVLMGLTGFMLVSLCLAFVNNVELFLALRFAQAFIGAAATVVVPGYIKEVYGENTAKGMSYVSLIMMLAPLIAPSIGSLILELGEWHLIFFILAAYAFILLALVLWKLKMPSDSDANSRSQKSFFGAYAVVFTKPGTKLHIASGVLTSFAFFCYLTASPFVYMEVFGLDKSLFAILFSTNVGALMLANVINSRIVVRYGSRLMLKVSTLLAMLAGSALLLVNLFGLSYHFTVAMLIPFMGFLGIMSVNADAIVLMKFKKETGTATAVIGTLRFGCGAMAGPLLALFYTGTAVPFSALMLSAVILVGLCQFFAAHGVQCEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQP7</accession>
    <name>B1KQP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxygen-independent coproporphyrinogen III oxidase</fullName>
            <ecNumber evidence="7">1.3.98.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2002</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.3.98.3" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324632.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2002"/>
    <dbReference type="EnsemblBacteria" id="ACA86286">
        <property type="protein sequence ID" value="ACA86286"/>
        <property type="gene ID" value="Swoo_2002"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2002"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027579_3_1_6"/>
    <dbReference type="OMA" id="FNFKANQ"/>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="35"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="448" mass="51470" checksum="573000524FD58F63" modified="2008-04-29" version="1">MTLPNLPFWKEYPTRDSEWVRQYPTRHHSIKEEEVFGKQQMGIYVHIPFCNRLCFSCPYIKHQTDKTITRRYLDALKTEISNYAARPYVQDHEITLGYIGGGTPTALSSAELEELLGHLHSELNMSDDVELSIETTPIDITKKKAETLYNNGVKRISLGVQTFVQEELESIGRPSDPKMLENAIKICQEAGFTNINIDLMHGLNGQTMESWEYSLDKAIELGVTCVSFYTYMEFAQVSTKRRKLPPVPTTDVVDEMFMFAAKKLTENGFDGYFGDCFAKPGYQPRYGERSWSENIPIIPLGPTATGHLKDHWYFNEPSINKYIEVVNSGQLPISMGQYISKEEAIRRGMILGVKASKVDRKMFKHLYGVDFVEKFQSEIQDLESKGLVELTQNELKVTDPKGWYYLDNISKTFYSESFKRYPQHLGSDITEFQSSVAEWQPIEITTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR21</accession>
    <name>B1KR21_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0542"/>
    <dbReference type="EnsemblBacteria" id="ACA84838">
        <property type="protein sequence ID" value="ACA84838"/>
        <property type="gene ID" value="Swoo_0542"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0542"/>
    <dbReference type="eggNOG" id="ENOG5032XSE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1097921_0_0_6"/>
    <dbReference type="OMA" id="VTYYFAP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="253" mass="28301" checksum="FB565C832E4CF2EA" modified="2008-04-29" version="1" precursor="true">MRHAIGATTPLMSILILTSALVGVSNRAFASDELAKPLDLPLASCNRISHYAIYLSGIHTGTMSRTETWQGKTAVVSSESKASILGIGTQYQQRAELSWSDSTHEWLTDNFHQKVTGFRSRDMRASFKEAGLESRVDIDGEIDTYSSKTIPIRDVDTLAIQIREYLLQGRKQFALIRQASDAIEPYQLYVQELQSENIAPWGELSLIPVEQTGAEDVTYYFAPALDYQLVKARYHGFILHGLIELDSYTSTCE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR25</accession>
    <name>AROQ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="1">3-dehydroquinase</shortName>
            <ecNumber evidence="1">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroQ</name>
        <name type="ordered locus">Swoo_0546</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323190.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KR25"/>
    <dbReference type="SMR" id="B1KR25"/>
    <dbReference type="STRING" id="392500.Swoo_0546"/>
    <dbReference type="EnsemblBacteria" id="ACA84842">
        <property type="protein sequence ID" value="ACA84842"/>
        <property type="gene ID" value="Swoo_0546"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0546"/>
    <dbReference type="eggNOG" id="COG0757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090968_1_0_6"/>
    <dbReference type="OMA" id="AYTHYSY"/>
    <dbReference type="OrthoDB" id="1872106at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000097624" description="3-dehydroquinate dehydratase">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="102"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <sequence length="149" mass="16163" checksum="3072135164FEAAC9" modified="2008-04-29" version="1">MSAKAKILLVNGPNLNLLGRREPGHYGHHTLDSIVQNMKNTANSADVELEHIQSNAEHELIDAIHSTDANFIIINPAAFTHTSVAIRDAILGVAIPFIEVHLSNVHAREPFRHHSYFSDKAVGVICGLGADGYQFALKSAINRLQGPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR71</accession>
    <name>B1KR71_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323236.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0592"/>
    <dbReference type="EnsemblBacteria" id="ACA84888">
        <property type="protein sequence ID" value="ACA84888"/>
        <property type="gene ID" value="Swoo_0592"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0592"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_12_4_6"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="15305" checksum="06FF468A447A4522" modified="2008-04-29" version="1">MAMTFNHLNLLASADSGIFTLLVDTLGLEVGQRPDFPFKGHWLYQGDKALVHIIESQAYQECQLGHLAFELNMNLQELTTKLQQSAIQYSVKQVPDSEIVQVFVRVGNMVFELQTLNEPRNNQFPIFTQHEELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR97</accession>
    <name>B1KR97_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Secretion protein HlyD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324650.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2020"/>
    <dbReference type="EnsemblBacteria" id="ACA86304">
        <property type="protein sequence ID" value="ACA86304"/>
        <property type="gene ID" value="Swoo_2020"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2020"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_775887_0_0_6"/>
    <dbReference type="OMA" id="CTIVDMD"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="86"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="181"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="357" mass="39167" checksum="4199B0D13DA36877" modified="2008-04-29" version="1">MASREDLIKQLDASDDVDTTSNKFITLKSLSITALIVVSIIFSISKLAVEGDKSEEYPITPQGAVEGESIIDAQVSSPVTETVVLQASGYIMAKKMMTVSSNVSGRLNSIMIEEGMRVKQGELLATFDDSIPQTELKMLESQYSYGLARLKESEAEYTGHQVSLRRIQRLFDSGNGSVAELDEMKTKANILEARVAVASRELEIAKENINTQLRRLLEYKVYSPMQGVVVDVMAQAGEVISSLTTFGTDEQSGICTIVDMNSLHVEVEVSEQYISRVAVGQRALAKLNAYPDLPVDIEVALIVPTANKDKSTVKVWLNIIKNDPRILPEMGVEVSFFPPDEEEEQGHLTSKLSDVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR98</accession>
    <name>B1KR98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2021"/>
    <dbReference type="EnsemblBacteria" id="ACA86305">
        <property type="protein sequence ID" value="ACA86305"/>
        <property type="gene ID" value="Swoo_2021"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2021"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="NICKFYS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="24508" checksum="B0867BBB691A4B39" modified="2008-04-29" version="1" precursor="true">MSAITINGLSKSYKLKKQEIPVLHDIELNIEQGEFVALMGPSGSGKSTLLNVIGGIDKSDSGEVLVAGKRLDECSDSELTKWRGDNVGIVFQSYNLIPVLSAEENVRLPLYKTKLSRKEQKKRVAAALELVGLADRAKHKPTQLSGGQQQRIAIARALVSNASILICDEPTGDLDREMADKVLGLLKTLNTSIGKSIIMVTHDPKAASYADRILYMDKGYIEDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRL3</accession>
    <name>B1KRL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326111.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3514"/>
    <dbReference type="EnsemblBacteria" id="ACA87778">
        <property type="protein sequence ID" value="ACA87778"/>
        <property type="gene ID" value="Swoo_3514"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3514"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_28_6"/>
    <dbReference type="OMA" id="CHEEFLC"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="125"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="285"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="427" mass="47904" checksum="3B0015C386A9F77D" modified="2008-04-29" version="1">MMNNLLVVEDNKAIASVIEHIGGSLGYRVTIAYSFAELKSLLVSHHDFFAATVDYSLPDAVDGQAIFHVLEHNIPCIVMTGKMNNTIHQKLLSLPIVDYLTKENSQAYHYLLRVLHGQLTNHEIGVLVVDDSLSVRSYVCNLLSRRNFTLYDVPDGTKALNALAMHPEIKLIITDQEMPGMNGIELVQAVRKQFADRELVIVGYSGIDKPYQSARFIKSGADDYLQKPFCPEEFYCRVFKNVEKLQYIEEIKMAADMDYLTSLSNRRHFIEQLTEHFDELLVNNLEHLLIFIHVDDFKGINESFGHSGGDKILVELAELLKKSIEPPYRARFGGAEFCCLISGSSLVKNREQVEKLTQAASALSFTLKEREMCFKISVGGAQMCDKSTVKTLLSQADTAFQKALSQGGNSTVIHEVQEGEKEKSRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRM0</accession>
    <name>B1KRM0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326118.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3521"/>
    <dbReference type="EnsemblBacteria" id="ACA87785">
        <property type="protein sequence ID" value="ACA87785"/>
        <property type="gene ID" value="Swoo_3521"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3521"/>
    <dbReference type="eggNOG" id="COG3292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_28_2_6"/>
    <dbReference type="OMA" id="SGGLWQV"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011110">
        <property type="entry name" value="Reg_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011123">
        <property type="entry name" value="Y_Y_Y"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07494">
        <property type="entry name" value="Reg_prop"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07495">
        <property type="entry name" value="Y_Y_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="783"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="894"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="1001"/>
            <end position="1232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1237" mass="140594" checksum="D1E7D60A65030933" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRN0</accession>
    <name>B1KRN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87795">
        <property type="protein sequence ID" value="ACA87795"/>
        <property type="gene ID" value="Swoo_3531"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3531"/>
    <dbReference type="eggNOG" id="ENOG50345Q9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1641226_0_0_6"/>
    <dbReference type="OMA" id="WAEHWSE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019629">
        <property type="entry name" value="Uncharacterised_HI1736/YgjV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10688">
        <property type="entry name" value="Imp-YgjV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="18142" checksum="876214C0B11C9D9A" modified="2008-04-29" version="1">MFLAWWANAQRDDKALLSGNLIASGLTAIHLGLLGSPLGMVNQLLNMGRFFSSRYYRISILAPIFASLAIIQGFLWAEHWSEWCAVLAGVIMSFALIYCQGTQLRLSILVSNICNLTLSLHLHSWSGVIYQIITIGMITYQLTTDTHYDKSGNEPSYNQALAK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRQ5</accession>
    <name>PNP_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Polynucleotide phosphorylase</fullName>
            <shortName evidence="1">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pnp</name>
        <name type="ordered locus">Swoo_3556</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326153.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRQ5"/>
    <dbReference type="SMR" id="B1KRQ5"/>
    <dbReference type="STRING" id="392500.Swoo_3556"/>
    <dbReference type="EnsemblBacteria" id="ACA87820">
        <property type="protein sequence ID" value="ACA87820"/>
        <property type="gene ID" value="Swoo_3556"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3556"/>
    <dbReference type="eggNOG" id="COG1185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004217_2_2_6"/>
    <dbReference type="OMA" id="LHILDVM"/>
    <dbReference type="OrthoDB" id="122725at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="SSF46915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000192491" description="Polyribonucleotide nucleotidyltransferase">
        <location>
            <begin position="1"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="KH" evidence="1">
        <location>
            <begin position="552"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="621"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <sequence length="702" mass="75726" checksum="8AA863EAB0F7E266" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCY8</accession>
    <name>B1KCY8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase</fullName>
            <ecNumber evidence="3">4.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0018</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322668.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0018"/>
    <dbReference type="EnsemblBacteria" id="ACA84319">
        <property type="protein sequence ID" value="ACA84319"/>
        <property type="gene ID" value="Swoo_0018"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0018"/>
    <dbReference type="eggNOG" id="COG2606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094875_1_1_6"/>
    <dbReference type="OMA" id="PYDYVEH"/>
    <dbReference type="OrthoDB" id="1503081at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00002">
        <property type="entry name" value="YbaK_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004369">
        <property type="entry name" value="Prolyl-tRNA_editing_YbaK/EbsC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006181">
        <property type="entry name" value="EbsC_YbaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00011">
        <property type="entry name" value="YbaK_EbsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="4">
        <location>
            <begin position="32"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="155" mass="16560" checksum="1E9E406DED461D36" modified="2008-04-29" version="1">MTPAINSLKRAKLAYRILEYHHDANAGAYGIEAAAKLNLAPSLVFKTLVAKLDNEKLVVAIIPVAEKLNMKLLAKAAGVKKAAMASAQEVERSTGYVLGGVSPLGQKRPLATFIDISAESLKQIYVSGGKRGLDIELTPMSLQQLTKANFTPLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD41</accession>
    <name>B1KD41_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 26">Na(+)-translocating NADH-quinone reductase subunit F</fullName>
            <shortName evidence="26">Na(+)-NQR subunit F</shortName>
            <shortName evidence="26">Na(+)-translocating NQR subunit F</shortName>
            <ecNumber evidence="7 26">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="25 26">NQR complex subunit F</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="24 26">NQR-1 subunit F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="primary">nqrF</name>
        <name evidence="29" type="ordered locus">Swoo_3612</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="29 30" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="30">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 26">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 26">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="26">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="26">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 26">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6 26">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="26">Cell inner membrane</location>
            <topology evidence="26">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 26">Belongs to the NqrF family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="7 26"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326209.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3612"/>
    <dbReference type="EnsemblBacteria" id="ACA87876">
        <property type="protein sequence ID" value="ACA87876"/>
        <property type="gene ID" value="Swoo_3612"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3612"/>
    <dbReference type="eggNOG" id="COG2871">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_7_2_6"/>
    <dbReference type="OMA" id="FIKEFVV"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00430">
        <property type="entry name" value="NqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010205">
        <property type="entry name" value="NqrF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000044">
        <property type="entry name" value="Cis_Diol_DH_RD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01941">
        <property type="entry name" value="nqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 26" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10 26" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9 26" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14 26" id="KW-0274">FAD</keyword>
    <keyword evidence="11 26" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="20 26" id="KW-0406">Ion transport</keyword>
    <keyword evidence="16 26" id="KW-0408">Iron</keyword>
    <keyword evidence="17 26" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="22 26" id="KW-0472">Membrane</keyword>
    <keyword evidence="13 26" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18 26" id="KW-0520">NAD</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="19 26" id="KW-0915">Sodium</keyword>
    <keyword evidence="23 26" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="15 26" id="KW-1278">Translocase</keyword>
    <keyword evidence="26" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="26" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="26" id="KW-0813">Transport</keyword>
    <keyword evidence="21 26 29" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="27">
        <location>
            <begin position="40"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="28">
        <location>
            <begin position="137"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00019729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00030032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00030787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="ACA87876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="415" mass="45720" checksum="23F6070845C93289" modified="2008-04-29" version="1">MDILKSTPLEVYLGVSMFTAIVLGLVLVILFAKSKLVNSGDITIGINDDPDKGIKLPAGGKLLGALAESGIFVSSACGGGGTCGQCKVNVKSGGGDILPTELGHISKGEAREGCRLSCQVNVKTDMEIELEEEIFGVKKWECTVISNDNKATFIKELKLQIPDGDSVPFRAGGYIQIEAPAHHVKYADYDIPAEYRGDWDHFGFFKLESKVDDETIRAYSMANYPEEEGIIMLNVRIASPPPRDLTLPCGKMSSYIFSLNAGDKVTISGPFGEFFAKDTENEMVFVGGGAGMAPMRSHIFDQLKRLKTDRKMSFWYGARSKREMFYVEDFDGLAADNENFDWHVALSDPQPEDNWEGKTGFIHNVLYESYLRDHEAPEDCEYYMCGPPMMNAAVIGMLKDLGVEDENILLDDFGG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD73</accession>
    <name>Y3646_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0234 protein Swoo_3646</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_3646</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0234 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326241.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KD73"/>
    <dbReference type="SMR" id="B1KD73"/>
    <dbReference type="STRING" id="392500.Swoo_3646"/>
    <dbReference type="EnsemblBacteria" id="ACA87908">
        <property type="protein sequence ID" value="ACA87908"/>
        <property type="gene ID" value="Swoo_3646"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3646"/>
    <dbReference type="eggNOG" id="COG1666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099839_1_0_6"/>
    <dbReference type="OMA" id="SDFDRQE"/>
    <dbReference type="OrthoDB" id="1612988at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd11740">
        <property type="entry name" value="YajQ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00632">
        <property type="entry name" value="UPF0234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007551">
        <property type="entry name" value="DUF520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035570">
        <property type="entry name" value="UPF0234_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036183">
        <property type="entry name" value="YajQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30476">
        <property type="entry name" value="PTHR30476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04461">
        <property type="entry name" value="DUF520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89963">
        <property type="entry name" value="SSF89963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000130651" description="UPF0234 protein Swoo_3646">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00632"/>
        </source>
    </evidence>
    <sequence length="161" mass="18311" checksum="D1510EE23D288047" modified="2008-04-29" version="1">MPSMDIVSEVDEVELRNAVDNSVRELKSRFDFRGKDASIEYKDHVVTLSAEDDFQCQQLVDILRMQLSKRNVDPASMDVDDKSVHSGKTFSLKVRFKEGIEVLTAKKLVKIIKDSKLKVQSSIQGDSVRVTGKKRDDLQAVMTLARESGLDQPFQFNNFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD93</accession>
    <name>B1KD93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3666</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326261.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3666"/>
    <dbReference type="EnsemblBacteria" id="ACA87928">
        <property type="protein sequence ID" value="ACA87928"/>
        <property type="gene ID" value="Swoo_3666"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3666"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_6"/>
    <dbReference type="OMA" id="SMKGAME"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="255" mass="27980" checksum="89E7B8C12741C6CE" modified="2008-04-29" version="1">MTISQLDYRLGGRGVFITGGASGIGAALVRAFVEQGANVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTDTKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAYLVMKQRKQGVIINFSSNMAYIGERNMAGYITAKAGIAGMTKALAKDYGESRVRVNAIVPGWVATQRQLEQWLSPEQEQQLMEKVAIQKRITPEDIAKLALFLTSEDSELITGQCMVIDGGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDB0</accession>
    <name>B1KDB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA/MotB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0615</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323259.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0615"/>
    <dbReference type="EnsemblBacteria" id="ACA84911">
        <property type="protein sequence ID" value="ACA84911"/>
        <property type="gene ID" value="Swoo_0615"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0615"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095356_0_0_6"/>
    <dbReference type="OMA" id="SINCMEY"/>
    <dbReference type="OrthoDB" id="2018797at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766964" evidence="3">
        <location>
            <begin position="26"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="113"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="25242" checksum="CEA1C36C1ECA8DA7" modified="2008-04-29" version="1" precursor="true">MASKTCSTFISILSLSWLLSGCAQEMVSEPMQPQASEQGQYELASFCSAKGYNLSQNVTISDVAGIANHRDGYLMIRQDSDQAEIKTALLKLAKNQDVSINCMEYLSSNGLVEFGSGEGLLARVYFDFDSKSLTPESRLILDKVAKRLVQAPEVIKLVGHTDNSGSEEYNYSLGLLRADNAQTYLNKQGVRDTQLKSESQGETRPIASNENLDGRALNRRVELLQVTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDB2</accession>
    <name>B1KDB2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323261.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0617"/>
    <dbReference type="EnsemblBacteria" id="ACA84913">
        <property type="protein sequence ID" value="ACA84913"/>
        <property type="gene ID" value="Swoo_0617"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0617"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_4_2_6"/>
    <dbReference type="OrthoDB" id="1925754at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="51"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21350" checksum="4EBE2C5004A344C7" modified="2008-04-29" version="1">MSDLPVLSEEEFKNKFPEVHQQVCDELGMGFVPAIFRCVALLNPDLAMSSWNMVRKNLCAGDLPRITKELMFSYIAHKKKCHYCTVAHHALALHHGFTEQDMAVILKDIEQIKNPSLKLVMKLADASVDNDFKRVSKLDNELCSLGFARDEITELVGMISCALYMINLADSIGIDADKRFTDTIDKASLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD9</accession>
    <name>B1KDD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323287.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0644"/>
    <dbReference type="EnsemblBacteria" id="ACA84940">
        <property type="protein sequence ID" value="ACA84940"/>
        <property type="gene ID" value="Swoo_0644"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0644"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_7_6"/>
    <dbReference type="OMA" id="VELANWA"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="149"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="221" mass="24677" checksum="537BC45015C80A73" modified="2008-04-29" version="1">MNQIDELVFFHQIEAPCHLAILAQSIGLKTRIVSKSSELFDGLLSNSFCFIAQKGEALDNKGIPLIASRLASHCPVALHQVEPNTLEVESALLLGIKGVLYSNQGMDSLMSGITNMVEGELYFDRQLISQVFSRLVRKLDSANDTLQDSAVMMQMLTSRERTIISLVSSGARNKEIAHRLCISEHTVKAHISSIFRKTQSRNRVELLRWAQSYQSQLELCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDH4</accession>
    <name>B1KDH4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323322.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0679"/>
    <dbReference type="EnsemblBacteria" id="ACA84975">
        <property type="protein sequence ID" value="ACA84975"/>
        <property type="gene ID" value="Swoo_0679"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0679"/>
    <dbReference type="eggNOG" id="COG3529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_186875_0_0_6"/>
    <dbReference type="OMA" id="DTLRWWI"/>
    <dbReference type="OrthoDB" id="2010281at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012658">
        <property type="entry name" value="CHP02443"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09526">
        <property type="entry name" value="DUF2387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02443">
        <property type="entry name" value="TIGR02443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="66" mass="7260" checksum="5C9403BE017E7C68" modified="2008-04-29" version="1">MADTKIKKRFVAGAKCPKCKAMDSIMLYKLNGVETVECTECDYTEQQADEQVANKATGNVIGVFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDR9</accession>
    <name>B1KDR9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DegT/DnrJ/EryC1/StrS aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2184</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324810.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2184"/>
    <dbReference type="EnsemblBacteria" id="ACA86466">
        <property type="protein sequence ID" value="ACA86466"/>
        <property type="gene ID" value="Swoo_2184"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2184"/>
    <dbReference type="eggNOG" id="COG0399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033332_7_2_6"/>
    <dbReference type="OMA" id="IMGLNFR"/>
    <dbReference type="OrthoDB" id="1722208at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="394" mass="43538" checksum="D105FF8DE5EA8CA9" modified="2008-04-29" version="1">MPGFELFGPEEKQEVADVMENGFTFRYNFDHMRNDRWKTREMEQLLCEKMGVKHAHLLSSGTAALQTALAAAGIGAGDEVIVPPFTFVASVEAVFMAGAVPIFAEIDETLCLSPEGIEAAITPRTKAVNLVHMCGSMGKLDEIKAICEKHDLVLLEDACQAIGGTYKGQALGTIGDVGCYSFDSVKTITCGEGGAVITNSETIYKNSHMFSDHGHDHVGNDRGAEGHPIMGLNFRISEMNSAMGLAQLRKLDTIIDIQRKNKNTIKSAIADIADISFRELPDVKGDSAGFLTFMMPTEERTIEINKKLAENGVDGCFYWYVNNWHYLSNWKHIQELKSCSALPITLIEDRPDYTQVSVPKSDAIMSRTISMLIKLSWTEDEIAQRIENIKRAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDY5</accession>
    <name>B1KDY5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3727</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3727"/>
    <dbReference type="EnsemblBacteria" id="ACA87987">
        <property type="protein sequence ID" value="ACA87987"/>
        <property type="gene ID" value="Swoo_3727"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3727"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_6"/>
    <dbReference type="OMA" id="TWMYRIV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="122"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="20892" checksum="C7A2DB668E12C464" modified="2008-04-29" version="1">MSAQLAFIKPCETSEKNLIEQAQQGNKKAFKQLYDLHHKRVYALCYRLSGQHYLAEEATQETFVRLWQKLPQFRGDSQFSTWLHSMTVNQALSSIKKHKSFWARFSPIYEQVELGGDEMEYQALDKHLLKLPERARIVFVLFAVEGYQHHEIAHKLNIAQGTSKAQYHRARKLLQEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDY9</accession>
    <name>B1KDY9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH-type transcriptional regulator MetR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3732</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326323.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3732"/>
    <dbReference type="EnsemblBacteria" id="ACA87991">
        <property type="protein sequence ID" value="ACA87991"/>
        <property type="gene ID" value="Swoo_3732"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3732"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_6"/>
    <dbReference type="OMA" id="YPVPDDM"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08441">
        <property type="entry name" value="PBP2_MetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037406">
        <property type="entry name" value="MetR_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="7">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="33836" checksum="017170B9955DC08A" modified="2008-04-29" version="1">MIELRHLRTLLALKESGSLAGAAKKRFVTQSALSHQIKELETRINSSIFIRKSKPLAFTQEGARLLNLAEEILPKVIETEYDLKQGLNEGGNQLGVGIECHSCFRWLMPVMEQFRTTFPQVNLDLSSRHLFDSLNALEMGELDVVLTSDPVPGQAIAYQHLFDFEVKLVVSKDHPLAKLEYVTAQQLEKQTIISYPVPLERLDLYRHFMEPAGVEAGEQLHCDLTMMLLQRIACRDGVAALPTWSISESYGLNLTSVKLGAEGLKRPLFGAYRKDGRNVRTAQNWLTLVANEGLAKQHKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDZ4</accession>
    <name>B1KDZ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional repressor, CopY family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326328.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3737"/>
    <dbReference type="EnsemblBacteria" id="ACA87996">
        <property type="protein sequence ID" value="ACA87996"/>
        <property type="gene ID" value="Swoo_3737"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3737"/>
    <dbReference type="eggNOG" id="COG3682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119090_2_1_6"/>
    <dbReference type="OMA" id="KWEKSTI"/>
    <dbReference type="OrthoDB" id="2027769at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="123" mass="14120" checksum="DC2B30AFE112042F" modified="2008-04-29" version="1">MKEISNSELAVLNLLWHSSPMSSSEVVAQLNKSKQWHEKTVKTLLNRLVKKEAVGFEKQGRSYLYHPLIDQGEFQLKESQSFIERVFSGKLTPLVAGFAKENKLSSDDIAELKQLIDNWEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE23</accession>
    <name>B1KE23_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional protein PutA</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="2">Proline dehydrogenase</fullName>
                <ecNumber evidence="2">1.5.5.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="2">Proline oxidase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="2">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="2">P5C dehydrogenase</shortName>
                <ecNumber evidence="2">1.2.1.88</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="2">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0714</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Oxidizes proline to glutamate for use as a carbon and nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinone + L-proline = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the proline dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2"/>
    <dbReference type="EC" id="1.2.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323356.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0714"/>
    <dbReference type="EnsemblBacteria" id="ACA85009">
        <property type="protein sequence ID" value="ACA85009"/>
        <property type="gene ID" value="Swoo_0714"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0714"/>
    <dbReference type="eggNOG" id="COG0506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005682_1_0_6"/>
    <dbReference type="OMA" id="PPWNFPV"/>
    <dbReference type="OrthoDB" id="14333at2"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006561">
        <property type="term" value="P:proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025703">
        <property type="entry name" value="Bifunct_PutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005933">
        <property type="entry name" value="Delta1-pyrroline-5-COlate_DH-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041349">
        <property type="entry name" value="PRODH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024089">
        <property type="entry name" value="PRODH_PutA_dom_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024082">
        <property type="entry name" value="PRODH_PutA_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14850">
        <property type="entry name" value="Pro_dh-DNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18327">
        <property type="entry name" value="PRODH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000197">
        <property type="entry name" value="Bifunct_PutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81935">
        <property type="entry name" value="SSF81935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01238">
        <property type="entry name" value="D1pyr5carbox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="PRODH" evidence="8">
        <location>
            <begin position="22"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_dh-DNA_bdg" evidence="7">
        <location>
            <begin position="76"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_dh" evidence="6">
        <location>
            <begin position="200"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="577"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="811"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000197-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1059" mass="115331" checksum="1BCECDC5BB2FF8F0" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB1</accession>
    <name>B1KEB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324833.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2207"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86489">
        <property type="protein sequence ID" value="ACA86489"/>
        <property type="gene ID" value="Swoo_2207"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2207"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_7_3_6"/>
    <dbReference type="OMA" id="IVGEEWS"/>
    <dbReference type="OrthoDB" id="148706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015171">
        <property type="entry name" value="Cyc-maltodext_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019492">
        <property type="entry name" value="Cyclo-malto-dextrinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10438">
        <property type="entry name" value="Cyc-maltodext_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09087">
        <property type="entry name" value="Cyc-maltodext_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764339" evidence="1">
        <location>
            <begin position="24"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="134"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="631" mass="71897" checksum="1F0E60A97856284B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB3</accession>
    <name>B1KEB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Outer membrane insertion C-terminal signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324835.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2209"/>
    <dbReference type="EnsemblBacteria" id="ACA86491">
        <property type="protein sequence ID" value="ACA86491"/>
        <property type="gene ID" value="Swoo_2209"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2209"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="DLTWAGM"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766495" evidence="5">
        <location>
            <begin position="25"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="59"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="420"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="908" mass="100098" checksum="B9ED645CAAAAE4D3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB7</accession>
    <name>B1KEB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324839.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2213"/>
    <dbReference type="EnsemblBacteria" id="ACA86495">
        <property type="protein sequence ID" value="ACA86495"/>
        <property type="gene ID" value="Swoo_2213"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2213"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_34_6"/>
    <dbReference type="OMA" id="NEYYLGA"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="341"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="484"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="742" mass="83487" checksum="B0E7B51F35A6A7FE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW7</accession>
    <name>B1KEW7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein adenylyltransferase SelO</fullName>
            <ecNumber evidence="9">2.7.7.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">selO</name>
        <name evidence="10" type="ordered locus">Swoo_0823</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-seryl-[protein] = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:58120"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:15073"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:142516"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54292"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13847"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138113"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:13846"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SELO family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.n1" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0823"/>
    <dbReference type="EnsemblBacteria" id="ACA85118">
        <property type="protein sequence ID" value="ACA85118"/>
        <property type="gene ID" value="Swoo_0823"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0823"/>
    <dbReference type="eggNOG" id="COG0397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010245_4_1_6"/>
    <dbReference type="OMA" id="YQFGEYN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PTHR32057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="126"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="493" mass="54428" checksum="38DA276704A34A49" modified="2008-04-29" version="1">MSNKEIDLGLTFDNSYFDKLEGFYVACSGAKAPDPKLIKLNGALANRVGLTNADPTSLAQVLSGTIAPSGSSPLAQVYAGHQFGGFSPQLGDGRALLLGEVLDKDGIRLDIQLKGSGRTPFSRGGDGKAVLGAVLREYIVSEAMFALDIPTTRALAVVTSGESVMRSQYLPGAVLTRVASSHLRVGTFQFFASRGENDKVKQLADYAIARHYPKVEESEQRYLDFLCAVRDKQAELVAKWLLVGFIHGVMNTDNMTISGETIDYGPCAFMDDYGSDTVFSSIDRDGRYSYNNQPVMAQWDLARLAETLLPLIHDDQDEAIALATTAVTGFWEVFQQHWTAGMRRKLGLSDQEEGDFALGEQLLESMSGEEVDFTQLFRQLALDLQSGSHESQKLFNNADKFLVWKEEWETRLAKESLTVSKRIEMMNSANPIYIPRNHQVERAIEAAEMRGDYQPFEQLLAVLATPFTLQKEAQEYAEPAPADFGPYTTFCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF78</accession>
    <name>B1KF78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324961.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2340"/>
    <dbReference type="EnsemblBacteria" id="ACA86619">
        <property type="protein sequence ID" value="ACA86619"/>
        <property type="gene ID" value="Swoo_2340"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2340"/>
    <dbReference type="eggNOG" id="ENOG5032PJR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135455_1_0_6"/>
    <dbReference type="OMA" id="KILWLSP"/>
    <dbReference type="OrthoDB" id="2062478at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025695">
        <property type="entry name" value="DoxX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13781">
        <property type="entry name" value="DoxX_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14613" checksum="7691863710CEAF74" modified="2008-04-29" version="1">MPSIQVARVIISFSWLYHGIFPKLVQIAPLEMVMTTSLGLSNELSYLVIKLTGIIEIAFGILFFIYYRSKRIILLNIIALSSLLCFVTFMQPHLLIEAFNPVTTNLPLIALSFILLNEIKRESRLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF79</accession>
    <name>B1KF79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324962.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2341"/>
    <dbReference type="EnsemblBacteria" id="ACA86620">
        <property type="protein sequence ID" value="ACA86620"/>
        <property type="gene ID" value="Swoo_2341"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2341"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155918_0_0_6"/>
    <dbReference type="OrthoDB" id="1976609at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025695">
        <property type="entry name" value="DoxX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13781">
        <property type="entry name" value="DoxX_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="14957" checksum="D78E1D06B6D76288" modified="2008-04-29" version="1">MTQPLLLKAAIYSLAFLWIFTGLTSLFFSPEIGYQILTEANISGSFADVAIYSGGFLDILIGIWLLIPFKRKLCCIAQVTVIVTYTLLLTFIDIGFWLHPFGPVTKNIPIVVLIGYVYLSCLNSTSDNENKINGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFF9</accession>
    <name>B1KFF9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326464.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88134">
        <property type="protein sequence ID" value="ACA88134"/>
        <property type="gene ID" value="Swoo_3876"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3876"/>
    <dbReference type="eggNOG" id="ENOG5032NYW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107608_0_0_6"/>
    <dbReference type="OMA" id="EPYDAFD"/>
    <dbReference type="OrthoDB" id="1637933at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="19163" checksum="BE222535673210BB" modified="2008-04-29" version="1">MDRSFPEILKKLHEIEIDYADGEGIDFEPFDEFYSEEETSDWIKAWTGNDTLDGNEYLIYGQDGTGGYVAFWCVRKNADLLEQPIVFFGSEGEVGVVAQSFSDYVWLFANGIGPYEAVAYPDLERPKSQDFIRFATEYAPSSKSTASQIVEKAKAEFPDFEGIIDRLCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ5</accession>
    <name>B1KFQ5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Alkyl hydroperoxide reductase C</fullName>
            <ecNumber evidence="4 11">1.11.1.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 11">Peroxiredoxin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_0928</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>a hydroperoxide + H(+) + NADH = an alcohol + H2O + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:62628"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.11.1.26"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.26" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323568.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0928"/>
    <dbReference type="PeroxiBase" id="4901">
        <property type="entry name" value="SwoAhpC"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85221">
        <property type="protein sequence ID" value="ACA85221"/>
        <property type="gene ID" value="Swoo_0928"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0928"/>
    <dbReference type="eggNOG" id="COG0450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_21_3_6"/>
    <dbReference type="OMA" id="FWYPKDF"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102039">
        <property type="term" value="F:alkylhydroperoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017559">
        <property type="entry name" value="AhpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF121">
        <property type="entry name" value="PTHR10681:SF121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03137">
        <property type="entry name" value="AhpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="4"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="10">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="20758" checksum="82314A94098EB06E" modified="2008-04-29" version="1">MNQSIINTEIKPFSATAFHKGEFVPVSEQDLLGKWSVVFFYPADFTFVCPTELGDMADHYEKLQSMGVEVYSVSTDTHFTHKAWHDASDTINKINYPMIGDPTGTITRNFGVMIEEDGLALRGTFVINPEGEIKVAEVHDLGIGRSAAELVRKIQAAQYVAEHDGEVCPAAWQPGAETLAPSLDLVGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW4</accession>
    <name>B1KFW4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85280">
        <property type="protein sequence ID" value="ACA85280"/>
        <property type="gene ID" value="Swoo_0987"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0987"/>
    <dbReference type="eggNOG" id="ENOG502ZEWM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_194631_0_0_6"/>
    <dbReference type="OMA" id="LIQTWIW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="58" mass="6471" checksum="3CC4DBB4EEA99C84" modified="2008-04-29" version="1">MLDSSKNQYPPLPLIQTWVWMMTQSGDTDIQKKGQNNLIASFGSLAKANEYIVKQGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG10</accession>
    <name>B1KG10_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TraR/DksA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2439</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325059.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2439"/>
    <dbReference type="EnsemblBacteria" id="ACA86717">
        <property type="protein sequence ID" value="ACA86717"/>
        <property type="gene ID" value="Swoo_2439"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2439"/>
    <dbReference type="eggNOG" id="COG1734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043144_4_2_6"/>
    <dbReference type="OrthoDB" id="1932026at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="5">
        <location>
            <begin position="49"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12689" checksum="1D6EF75128B6AACA" modified="2008-04-29" version="1">MAINTSAELSDEQLAFLQKLLNDELRKVNGNIDQLEAQTEATSKCSHLDAVDLASQIAAQRAAHSVLESQRQQLSEIERAMARLKVGTYGLCEQTGEPIGFERLAVLPWARHTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG14</accession>
    <name>B1KG14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2443</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="3">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325063.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2443"/>
    <dbReference type="EnsemblBacteria" id="ACA86721">
        <property type="protein sequence ID" value="ACA86721"/>
        <property type="gene ID" value="Swoo_2443"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2443"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_1_2_6"/>
    <dbReference type="OMA" id="RIAAYAM"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="6">
        <location>
            <begin position="6"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="5">
        <location>
            <begin position="356"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="176"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="469" mass="51299" checksum="47DCBF04CE5B3529" modified="2008-04-29" version="1">MSKHFDLIWIGTGQATMSIVPRLLAAGKKVAVIESGNFGGTCVNTGCTPTKTLVAAARAIFQAGRGDNFGFSVDNLQIDFEKIMAPQKRNRGNATSGIEQFLTNHQHCTVFKGRAEFVDDKSVKVNEDTISAEHIVIHVGARPVEPELPGIDIIEWLDNEKLLNLSELPHHLAIVGGGYIGLEFSQIFRRFGSKVTIFERGTALLAREDDDIGEIAEDILVSEGVEIIYNSQIESVSKGEGVDKINIHYTQAGEPKTLAASHTLFAIGRVPNSDSLNLAAAGIDTDNRGFIKVNQTVQTNHPHIYGVGDVNGKGAFTHTSVNDGEIFWDHYSRLMGLNDEAPELDRTLSMRDTTYSMFIDPPLARVGISEKEARQSSRSVLMATLPMSRISRAKEKQETKGVVKIFVDAESEEILGATVFGTGGDEIIGVFAPFMQSKASYKTFRRAVFPHPTVGELLPWALDDLTQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG44</accession>
    <name>B1KG44_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfur relay protein TusD/DsrE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2474</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DsrE/TusD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325093.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2474"/>
    <dbReference type="EnsemblBacteria" id="ACA86751">
        <property type="protein sequence ID" value="ACA86751"/>
        <property type="gene ID" value="Swoo_2474"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2474"/>
    <dbReference type="eggNOG" id="COG1553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132095_0_0_6"/>
    <dbReference type="OMA" id="PQDDRNI"/>
    <dbReference type="OrthoDB" id="1997912at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017463">
        <property type="entry name" value="Sulphur_relay_TusD/DsrE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03012">
        <property type="entry name" value="sulf_tusD_dsrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14176" checksum="8007DDC02943779C" modified="2008-04-29" version="1">MSKFIIQVNGPVYGSSASYSAYQFTQAALAAGHEINCVFFYQDGVLNTSSLNSPASDEFDLTRAWISLNQKYSVRLVNCVSAALRRGVISKTEADESKLPHWNMQSPFEMGGLGELVVGIEKTDRLVSF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG49</accession>
    <name>SYS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Seryl-tRNA synthetase</fullName>
            <shortName evidence="1">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">serS</name>
        <name type="ordered locus">Swoo_2479</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325098.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG49"/>
    <dbReference type="SMR" id="B1KG49"/>
    <dbReference type="STRING" id="392500.Swoo_2479"/>
    <dbReference type="EnsemblBacteria" id="ACA86756">
        <property type="protein sequence ID" value="ACA86756"/>
        <property type="gene ID" value="Swoo_2479"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2479"/>
    <dbReference type="eggNOG" id="COG0172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_1_1_6"/>
    <dbReference type="OMA" id="SPCFRRE"/>
    <dbReference type="OrthoDB" id="353391at2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000098124" description="Serine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="235"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="353"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <sequence length="428" mass="47008" checksum="D792246A67C4DE22" modified="2008-04-29" version="1">MLDPKFLRNELEATAESLATRGFILDVERLSKLEEKRKSLQVATEELQASRNAISKSIGQAKAKGEDVAPIMAQVGDLGSQLDSKKAELAELLEELNAIALSVPNLPDASAPIGKDESENVEVRRWGTIKEYGFEVKDHVELGETLGGLDFKSAVKITGSRFIIMKGQIARMHRALAQFMLDLHTTEHGYTETYVPLLVNEDSLMGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNIARDTIIDEAELPVKLTAHTPCFRSEAGSYGRDTRGLIRQHQFDKVELVQLVKPEDSMAALDALTGHAEKVLEKLGLPYRTVILCTGDMGFGSSKTFDIEVWLPAQNTYREISSCSNMQDFQARRMQARYKAADAKKPALLHTLNGSGLAVGRTLVAVLENYQNEDGSITVPEVLRPYMGGLEKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG68</accession>
    <name>B1KG68_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3948</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3948"/>
    <dbReference type="EnsemblBacteria" id="ACA88205">
        <property type="protein sequence ID" value="ACA88205"/>
        <property type="gene ID" value="Swoo_3948"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3948"/>
    <dbReference type="eggNOG" id="COG1863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086615_2_0_6"/>
    <dbReference type="OMA" id="KSMVYCI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002758">
        <property type="entry name" value="Cation_antiport_E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34584">
        <property type="entry name" value="PTHR34584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01899">
        <property type="entry name" value="MNHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="171" mass="19167" checksum="DEB9277D861C4322" modified="2008-04-29" version="1">MNDDKSTFEERAKYLPSHTLSLSVTLSLFWWINSNYGNLLLLSLGASSILLVIYIAYRMNVIDHESQPIHLSIKIPGYLLWLTKEIVLANISVVKHIWLGNSSISPTLETIDASQHTDLGKVIYANSITLTPGTVTVDLVDDRMTIHSLIKENIDTLKAGEMDSRVTELEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGR8</accession>
    <name>B1KGR8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4123 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325128.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2510"/>
    <dbReference type="EnsemblBacteria" id="ACA86787">
        <property type="protein sequence ID" value="ACA86787"/>
        <property type="gene ID" value="Swoo_2510"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2510"/>
    <dbReference type="eggNOG" id="ENOG502Z9DI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_873913_0_0_6"/>
    <dbReference type="OMA" id="AWSAHRW"/>
    <dbReference type="OrthoDB" id="612801at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025391">
        <property type="entry name" value="DUF4123"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13503">
        <property type="entry name" value="DUF4123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4123" evidence="1">
        <location>
            <begin position="29"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="339" mass="39392" checksum="FE7F59E8BFD595F3" modified="2008-04-29" version="1">MSDNRSLAEHSKQYDLFKILSEGSNRQVFLLVDPNHYDDFWTFWSSFQPKARQLWCYLFQESSYEALMSASPLIVVIEEGGAGETLYYWLLEQTSLFNKACILLESQCSLTELRHFWHQRISAIYPNGEQELLACYSPVVLAMLWPSLSSQEQLDFLGANTQFYLPCESVPDEEQVAQSDGKGEVRFSLLSKPAGTAAATEVIFSRDNPYRLSDSQYELLSRSQRRHRMVNDIFLRLSQYFSFELNIDQLSWLFLNSIEVAKESYPDESEFSFETFAVYRFVLEHDYFEKEAFKALMLKHDLRTSIQMFNQLNPPIYDEIFRAKQALWLAGVEQGSDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH62</accession>
    <name>B1KH62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326703.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4118"/>
    <dbReference type="EnsemblBacteria" id="ACA88374">
        <property type="protein sequence ID" value="ACA88374"/>
        <property type="gene ID" value="Swoo_4118"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4118"/>
    <dbReference type="eggNOG" id="ENOG503300P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174066_0_0_6"/>
    <dbReference type="OMA" id="KHKLVLW"/>
    <dbReference type="OrthoDB" id="2012088at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032036">
        <property type="entry name" value="DUF5062"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038316">
        <property type="entry name" value="DUF5062_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16691">
        <property type="entry name" value="DUF5062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="86" mass="9853" checksum="920D25B4EFAC7B6D" modified="2008-04-29" version="1">MKQGKHDPQLLKLAMEIGVGYAKKRGFADFDKGISPKDKVECIYRLLVTDKLIQPLAKDKEDGPNMKHKLILWITRQLPADHELLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHK6</accession>
    <name>B1KHK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AsmA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325231.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2614"/>
    <dbReference type="EnsemblBacteria" id="ACA86891">
        <property type="protein sequence ID" value="ACA86891"/>
        <property type="gene ID" value="Swoo_2614"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2614"/>
    <dbReference type="eggNOG" id="COG2982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012870_0_1_6"/>
    <dbReference type="OMA" id="FPWLGLE"/>
    <dbReference type="OrthoDB" id="1068066at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA" evidence="2">
        <location>
            <begin position="196"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="606" mass="64745" checksum="F634F32D25B8F949" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI77</accession>
    <name>B1KI77_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chorismate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1263</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323901.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1263"/>
    <dbReference type="EnsemblBacteria" id="ACA85555">
        <property type="protein sequence ID" value="ACA85555"/>
        <property type="gene ID" value="Swoo_1263"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1263"/>
    <dbReference type="eggNOG" id="COG0077">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027338_0_0_6"/>
    <dbReference type="OMA" id="TTIEVGH"/>
    <dbReference type="OrthoDB" id="1280729at2"/>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010952">
        <property type="entry name" value="CM_P_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01797">
        <property type="entry name" value="CM_P_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate dehydratase" evidence="8">
        <location>
            <begin position="106"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="300"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="662" mass="73179" checksum="C800932E14BF5E15" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI95</accession>
    <name>B1KI95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325286.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2670"/>
    <dbReference type="EnsemblBacteria" id="ACA86946">
        <property type="protein sequence ID" value="ACA86946"/>
        <property type="gene ID" value="Swoo_2670"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2670"/>
    <dbReference type="eggNOG" id="COG2370">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091372_0_0_6"/>
    <dbReference type="OMA" id="GFQPNTK"/>
    <dbReference type="OrthoDB" id="760572at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032809">
        <property type="entry name" value="Put_HupE_UreJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13795">
        <property type="entry name" value="HupE_UreJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="235" mass="25994" checksum="E2E57DAA10AA625A" modified="2008-04-29" version="1" precursor="true">MSQILANTLKMLMGLLLAILGLSVSFTLSAHGVDEATKQFLILNEGISILPFIYIGAKHMVTGYDHLLFLVGVIFFLFRGKDVLLYVSLFTLGHSITLLFGVLNDIEVNPYLIDAIIGFSIVYKGFDNLGGFKRVFGFQPNTKVAVMIFGLFHGFGLATKIQEFKLPQDGLVPNILAFNLGVEIGQFLVLGAVLILMSFWRRHRSYFQFSTATNTLLMSGGLMLVGFQLTGYFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA6</accession>
    <name>B1KIA6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chaperone NapD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">NapA signal peptide-binding chaperone NapD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">napD</name>
        <name evidence="5" type="ordered locus">Swoo_2681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with the cytoplasmic NapA precursor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NapD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325297.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2681"/>
    <dbReference type="EnsemblBacteria" id="ACA86957">
        <property type="protein sequence ID" value="ACA86957"/>
        <property type="gene ID" value="Swoo_2681"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2681"/>
    <dbReference type="eggNOG" id="COG3062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155794_5_3_6"/>
    <dbReference type="OMA" id="ENQGFIT"/>
    <dbReference type="OrthoDB" id="1976760at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005048">
        <property type="term" value="F:signal sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051224">
        <property type="term" value="P:negative regulation of protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02200">
        <property type="entry name" value="NapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005623">
        <property type="entry name" value="Chaperone_NapD_NO3_reduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38603">
        <property type="entry name" value="PTHR38603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03927">
        <property type="entry name" value="NapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="85" mass="9417" checksum="B5AC02D5501054FD" modified="2008-04-29" version="1" precursor="true">MSNELHVTSLVLQVQPDHMTAVRERIIEMNNAELSVNNEVKLVVVLEGDSQKSLMTDIETINAIPGVLSAAMVYHQSEVLEEGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC8</accession>
    <name>B1KIC8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2703</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325316.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2703"/>
    <dbReference type="EnsemblBacteria" id="ACA86979">
        <property type="protein sequence ID" value="ACA86979"/>
        <property type="gene ID" value="Swoo_2703"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2703"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_8_0_6"/>
    <dbReference type="OMA" id="RIPYPKW"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="5">
        <location>
            <begin position="53"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="235" mass="26825" checksum="22CE5474A7803D11" modified="2008-04-29" version="1">MSHTIKQKSQSKRATTTSKRGDQKRASWFNKNQPKSKAPQMRTGKGKTVEPVIVLFNKPFDVLCQFTDEQGRQTLKDFIPIPGVYAAGRLDRDSEGLLLLTNDGKLQSKLTEPKKKTFKTYWAQVEGAPDEAQLDLLRKGVELKDGMTLPAKISIMSQPTVWERVPPIRERKAIPTTWLEIQICEGRNRQVRRMTAHIGFPTLRLIRYKIGQWSLDDLSPGQYQSIDMKNKAVCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM1</accession>
    <name>B1KIM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326844.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4261"/>
    <dbReference type="MEROPS" id="S09.A77"/>
    <dbReference type="EnsemblBacteria" id="ACA88517">
        <property type="protein sequence ID" value="ACA88517"/>
        <property type="gene ID" value="Swoo_4261"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4261"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_3_0_6"/>
    <dbReference type="OMA" id="ARSEIDY"/>
    <dbReference type="OrthoDB" id="154149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="436"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="652" mass="74178" checksum="BEBB435CE37C91E7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIN4</accession>
    <name>B1KIN4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326857.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4274"/>
    <dbReference type="EnsemblBacteria" id="ACA88530">
        <property type="protein sequence ID" value="ACA88530"/>
        <property type="gene ID" value="Swoo_4274"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4274"/>
    <dbReference type="eggNOG" id="COG4798">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072291_1_0_6"/>
    <dbReference type="OMA" id="LFYHDLH"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="29455" checksum="E8537F1E65838A75" modified="2008-04-29" version="1" precursor="true">MRLPILAGLIAGISLVSVDAAPLSLSELNGILVSSDRPVKDSERDAARKPAQVMYFSGVEAGDNVLDLFAGGGWYSELFSKAVGPKGKVYAQNDNVIWRFAEKRINERTKGDRLANLTRFDKVDIVDMDIPAKSLDIAFTALNYHDLFFTHNVDEKTGKRTQFRKQAVDHRAALAKVRDSLKDDGVFIIIDHEAIKGSGYDAPNSEHRIDSNIVKYQMKEAGFKLVEEAFYLRNPDDDLSMNVFEKETRGKTDRFIYKFVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIX7</accession>
    <name>B1KIX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twitching motility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323971.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1333"/>
    <dbReference type="EnsemblBacteria" id="ACA85625">
        <property type="protein sequence ID" value="ACA85625"/>
        <property type="gene ID" value="Swoo_1333"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1333"/>
    <dbReference type="eggNOG" id="COG2805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013446_4_0_6"/>
    <dbReference type="OMA" id="WELDCSY"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01131">
        <property type="entry name" value="PilT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="345" mass="38406" checksum="D43B4CF5B6258109" modified="2008-04-29" version="1">MEITELLAFSVKHKASDLHLSAGVSPMIRVDGEVRKINLPALDHQGVHGLVYDIMNDKQRKDYEEHLEIDFSFEVPNLARFRVNAYNQSRGAAAVFRTIPSDILSLEQLGAPEIFKKISDFPRGLVLVTGPTGSGKSTTLAAMIDYINDNRHEHILTIEDPIEFVHQNKQCLINQREVHRHTHSFNAALRSALREDPDVILVGEMRDLETIRLAMTAAETGHLVFGTLHTTSAAKTIDRVVDVFPEGEKGMVRTMLSESLQAVISQTLIKKVGGGRVAAHEIMMGTPAIRNLIREDKVAQMYSAIQTGMAHGMQTLDQCLQNLVNRGQISREDAQHKSANKQTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIZ0</accession>
    <name>B1KIZ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1346</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323984.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85638">
        <property type="protein sequence ID" value="ACA85638"/>
        <property type="gene ID" value="Swoo_1346"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1346"/>
    <dbReference type="eggNOG" id="COG2860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064906_2_0_6"/>
    <dbReference type="OMA" id="MPKFDYQ"/>
    <dbReference type="OrthoDB" id="1665397at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="10"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="95"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="23137" checksum="FAC6A10191922980" modified="2008-04-29" version="1" precursor="true">MLEVKFISLLWLIGIIAEAMTGALAAGKKQMDLFGVVIIGCATAIGGGTLRDMLLGNYPLIWVENVHYLIAIAFASLLTVLIAPVMRYLSKVFLAIDALGLAVFSIIGAQKTLMLGFSPIVAVVMGVVTGVFGGVIRDILCNQVPLIFKKELYALVALLTAALYVSLKSFAVTEWINLAICLSFGFSFRMLAIKFHWGMPKFDYQYEHGHDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ46</accession>
    <name>B1KJ46_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325402.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2790"/>
    <dbReference type="EnsemblBacteria" id="ACA87066">
        <property type="protein sequence ID" value="ACA87066"/>
        <property type="gene ID" value="Swoo_2790"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2790"/>
    <dbReference type="eggNOG" id="ENOG50338JG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108934_0_0_6"/>
    <dbReference type="OMA" id="IHIVCGQ"/>
    <dbReference type="OrthoDB" id="1859700at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="168" mass="19288" checksum="DBF8ED45AFD16595" modified="2008-04-29" version="1">MHLSDTIDTKVISLGAHNPTYCFYLPTPPVFPKEWSLAQDDAISVLIEHNGNHWRKILTIMAKICAPSEDWKHYRDTHLLKHNEIILIGADTLLQTNIPQQKLWHFLVGSVVSQQLSIETQDLSFIEVNHNSKLVYDNQSLLITPYLDYRQFPNQLIAETRALIASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG6</accession>
    <name>B1KJG6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4386</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326964.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4386"/>
    <dbReference type="EnsemblBacteria" id="ACA88638">
        <property type="protein sequence ID" value="ACA88638"/>
        <property type="gene ID" value="Swoo_4386"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4386"/>
    <dbReference type="eggNOG" id="COG0798">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022869_0_2_6"/>
    <dbReference type="OMA" id="CTAMVLM"/>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="39070" checksum="68E1BD2FDC698C10" modified="2008-04-29" version="1">MGLFERYLSIWVGLSIVAGVLLGNLFPTIFVTVASLEYAHVNLVIALLIWIMIYPMMVQIDFAAVKDVRKSPKGLWLTLVINWLVKPFTMAFLGWLFFNVLFIDWVDPQTATEYIAGMILLGVAPCTAMVFVWSQLTKGDPNYTLVQVSVNDLIMVVAFAPICAFLLGVSDIEVPWETLLSSVFLYVVLPLVAGVLTRRRLEKKGELDSLTQLIAKLKPWSMVGLLMTVVLLFGFQAQTILNEPQNILLIAIPLLIQTYGIFFIAYYAAKRLKLSHKIAAPACMIATSNFFELAVAVAISLFGLHSGAALATVVGVLVEVPVMLSLVAFVNRNRAKFESDISSDEQSTPLSSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJH2</accession>
    <name>B1KJH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326970.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4392"/>
    <dbReference type="EnsemblBacteria" id="ACA88644">
        <property type="protein sequence ID" value="ACA88644"/>
        <property type="gene ID" value="Swoo_4392"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4392"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_10_2_6"/>
    <dbReference type="OMA" id="HALYNEE"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="384" mass="42497" checksum="3D0FED23988F6FB4" modified="2008-04-29" version="1">MTGLIALIKRELHALWRSPWQLALVSYIPILSILCLWWLFSAGLPRQLPVAIVDHDNSQLSRMLGRKLQANPVISPQSFVDLSSAVTAMKQAEVYGIIVFPYELKRDLVTGHSPTIDIRYNSQFLLVGKLLSSQIQMTLGAGLLEVAGGKLLLQGVPESKVSVNLSPVKSQTTALFNRNNNYVGFLVPPVLVALWQLLAMLIFSNSLSRELTCEGGLVPGTGVWSRVLAKVVLFTPILLMHGGFILALLYLYLGLPAAGSLALLMLAQFVMLLAVWLLVLLVFFIMRDSARIVSFGTAMFAPAFAFMGITFPVHEMPLVAQWWRLIMPSSHYVDSHVSIISYGAPWQTIALQLTSYWVFLLIIPVLVLLSRRLERASPSCENIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL1</accession>
    <name>B1KJL1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-oxalocrotonate decarboxylase</fullName>
            <ecNumber evidence="2">4.1.1.77</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324030.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1392"/>
    <dbReference type="EnsemblBacteria" id="ACA85684">
        <property type="protein sequence ID" value="ACA85684"/>
        <property type="gene ID" value="Swoo_1392"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1392"/>
    <dbReference type="eggNOG" id="COG3971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060136_4_1_6"/>
    <dbReference type="OMA" id="RIVGHKI"/>
    <dbReference type="OrthoDB" id="1314120at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047437">
        <property type="term" value="F:4-oxalocrotonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="86"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="28579" checksum="250311D71241DF68" modified="2008-04-29" version="1">MKPAEIEQLGLELYRALRNQEMLPPLTEREPQLTLDDAYQVSQCFLQHRLNDGERVVGKKIGLTSKVVQEMLGVHQPDFGFLTDAMMFESGSEIPFNSPLIQAKSEGEIAFILKADLKGPNVTPQDVIDATESVAACFEIVDSRVKDWKIKIEDTVADNASCGIFVMGDERVSPQDVDFENCQMVIKNRGEVVATGQGSAALGSPLNCVAWLANTLGDYGISLNAGDIILSGSLAAMLPCQADDDMSVEIEGIGTASYRFITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJV1</accession>
    <name>B1KJV1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH-quinone oxidoreductase subunit E</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NADH dehydrogenase I subunit E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">NDH-1 subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2863</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="9">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325474.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2863"/>
    <dbReference type="EnsemblBacteria" id="ACA87138">
        <property type="protein sequence ID" value="ACA87138"/>
        <property type="gene ID" value="Swoo_2863"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2863"/>
    <dbReference type="eggNOG" id="COG1905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054362_2_0_6"/>
    <dbReference type="OMA" id="HIIRYCD"/>
    <dbReference type="OrthoDB" id="1206880at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0830">Ubiquinone</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="19467" checksum="2D2CFA057D73D276" modified="2008-04-29" version="1">MATREQQTIPVSVVDTAEISLSSKEQQGIDELISHSPQLAGITIDALKLIQAERGWVSDASLHALSLYTQIPVADLDSVATFYNLIFRQPVGKVVLHPCDGISCDLMGGEHIRQCLKQQLNITAGETTTDNRFTLIPLPCLGACDKAPVMIANKQLFENMTTDELPKLLSTLSTFGEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW3</accession>
    <name>B1KJW3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor plug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325486.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2875"/>
    <dbReference type="EnsemblBacteria" id="ACA87150">
        <property type="protein sequence ID" value="ACA87150"/>
        <property type="gene ID" value="Swoo_2875"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2875"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_1_6"/>
    <dbReference type="OMA" id="QYPKPAG"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764585" evidence="5">
        <location>
            <begin position="32"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="53"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="365"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="896" mass="97611" checksum="9436CD1565BFAD84" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ9</accession>
    <name>B1KJZ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase of anthranilate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325522.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2913"/>
    <dbReference type="MEROPS" id="C26.960"/>
    <dbReference type="EnsemblBacteria" id="ACA87186">
        <property type="protein sequence ID" value="ACA87186"/>
        <property type="gene ID" value="Swoo_2913"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2913"/>
    <dbReference type="eggNOG" id="COG0512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_1_0_6"/>
    <dbReference type="OMA" id="HQVVIYR"/>
    <dbReference type="OrthoDB" id="1561172at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="21751" checksum="F5A7B9B748E5B6B4" modified="2008-04-29" version="1">MKLYLLDNFDSFTYNLVDQFRSLGYEVVIYRNDLDAKFIADKLLNEPSNAALVLSPGPGAPHEAGCLMALIALLAGKVPMLGICLGHQAMIEHYGGKVERAAQVVHGKASPTFHQQKGIFSHLPSPLPVARYHSLVATQVPDCLDVIATTEAMPMAISHKSHKAIGFQFHPESILTTLGSQLLTQTLNELTGMNSTQGANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK14</accession>
    <name>B1KK14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325537.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2928"/>
    <dbReference type="EnsemblBacteria" id="ACA87201">
        <property type="protein sequence ID" value="ACA87201"/>
        <property type="gene ID" value="Swoo_2928"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2928"/>
    <dbReference type="eggNOG" id="ENOG5032Z5H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077371_1_0_6"/>
    <dbReference type="OMA" id="CPEYHAF"/>
    <dbReference type="OrthoDB" id="1914957at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029074">
        <property type="entry name" value="Imm49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15575">
        <property type="entry name" value="Imm49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="295" mass="33270" checksum="DD9C3FF6E946DF85" modified="2008-04-29" version="1">MAKICPEIGLERLKGIGCSSHFIGQAVHAIETNTGSKQGCLLTLSDYSSAKSLLSWFQDGDLLQLRQHAYTAAKLERMYYQGASGEWQGAFCHFMALVSDYEPLINWQSQFISPLYRVTGGKAVRNRVGCPEYHAFQAILAMQSKWELLGERAEYILAHPPGKKMAKYQIDQEFYLALAKGDVSAMEQALHTLTVTKAKIRNFDGALGLTEHLMSMFGFIYAKIAWRAGYQVQVDSPYLPMEWLPVTPLAEYEEEYDFSADFELFQPFTNNYESLSPVTELSRRVDVTDGSLPVK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK48</accession>
    <name>SYR_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="1">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argS</name>
        <name type="ordered locus">Swoo_4427</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327005.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KK48"/>
    <dbReference type="SMR" id="B1KK48"/>
    <dbReference type="STRING" id="392500.Swoo_4427"/>
    <dbReference type="PRIDE" id="B1KK48"/>
    <dbReference type="EnsemblBacteria" id="ACA88679">
        <property type="protein sequence ID" value="ACA88679"/>
        <property type="gene ID" value="Swoo_4427"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4427"/>
    <dbReference type="eggNOG" id="COG0018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006406_5_1_6"/>
    <dbReference type="OMA" id="NKPLHLG"/>
    <dbReference type="OrthoDB" id="1146366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000095406" description="Arginine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <sequence length="581" mass="64957" checksum="641F0042194EEE30" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKA2</accession>
    <name>B1KKA2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327059.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4482"/>
    <dbReference type="EnsemblBacteria" id="ACA88733">
        <property type="protein sequence ID" value="ACA88733"/>
        <property type="gene ID" value="Swoo_4482"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4482"/>
    <dbReference type="eggNOG" id="ENOG50345TB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1561833_0_0_6"/>
    <dbReference type="OMA" id="CYLWLVW"/>
    <dbReference type="OrthoDB" id="1935864at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="171" mass="19980" checksum="528AD98ABC286605" modified="2008-04-29" version="1">MNPNMQKLMKISGLFRVLVLIATAVVVIYLGYSYLVEGELRFSTSHLFLELWHDERASRGVLLAIQTPLFITLFIGVYWLQKLLGYYQQGQFFGRESMTCYLWLIWLKVFDLVLDIAQILVTGYYHRSIFEHTSIELPIDFGDITTILLMLVIAYLLKAAKEIEEENREFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKA3</accession>
    <name>B1KKA3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4483</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327060.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4483"/>
    <dbReference type="MEROPS" id="S09.A77"/>
    <dbReference type="EnsemblBacteria" id="ACA88734">
        <property type="protein sequence ID" value="ACA88734"/>
        <property type="gene ID" value="Swoo_4483"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4483"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_3_1_6"/>
    <dbReference type="OMA" id="TIPPYWE"/>
    <dbReference type="OrthoDB" id="154149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764600" evidence="2">
        <location>
            <begin position="30"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="444"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="682" mass="76007" checksum="F0F8D40B5AF53EC4" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI0</accession>
    <name>B1KKI0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324166.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1532"/>
    <dbReference type="EnsemblBacteria" id="ACA85820">
        <property type="protein sequence ID" value="ACA85820"/>
        <property type="gene ID" value="Swoo_1532"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1532"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469202_0_0_6"/>
    <dbReference type="OMA" id="IWLTSWH"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="436"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="581" mass="65419" checksum="C61C69965CEC2A5D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKT5</accession>
    <name>B1KKT5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acyl-peptide hydrolase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acylaminoacyl-peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327067.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4490"/>
    <dbReference type="EnsemblBacteria" id="ACA88741">
        <property type="protein sequence ID" value="ACA88741"/>
        <property type="gene ID" value="Swoo_4490"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4490"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_0_2_6"/>
    <dbReference type="OMA" id="DENHWIM"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0007">Acetylation</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765008" description="Acyl-peptide hydrolase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="8">
        <location>
            <begin position="474"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="681" mass="77090" checksum="38325066CDB1877D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKX4</accession>
    <name>B1KKX4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsA</name>
        <name evidence="8" type="ordered locus">Swoo_4530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Self-interacts. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="5">Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the FtsA/MreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327106.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4530"/>
    <dbReference type="EnsemblBacteria" id="ACA88780">
        <property type="protein sequence ID" value="ACA88780"/>
        <property type="gene ID" value="Swoo_4530"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4530"/>
    <dbReference type="eggNOG" id="COG0849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037850_3_2_6"/>
    <dbReference type="OMA" id="DGIIRHT"/>
    <dbReference type="OrthoDB" id="1044637at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02033">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020823">
        <property type="entry name" value="Cell_div_FtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003101">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01174">
        <property type="entry name" value="ftsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="7">
        <location>
            <begin position="10"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR003101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="411" mass="44513" checksum="AFFBD7F7728DFF0C" modified="2008-04-29" version="1">MTKNQDRNLIVGLDIGTSKVAVIIGEVLPDGEISVVGLGNHQSRGMDKGGVNDLDSIVRSVQRALDQAELMADCQVSSVYLGISGKHISCQNENGMVSINDEEVTQDDVDNVIHTARSVKIPTERRILHVLPQEYAIDVQDGIKSPIGMSGMRMEAKVHIVTCANDMAKNITKSVERCGLKVDDLVFSAIASADSVLTNDEKDLGVCLVDIGGGTTDLAVYTNGALRHCAVVPVAGNQVTNDIAKIFRTPLSHAEQIKVQYASARSSMVSREDSIEVPSVGGRPSRSMSRHTLAEVVEPRYQELFELVLQELRDSGLEDQVAAGIVITGGTASIEGAVDVAEATFGMPVRVASPLPVKGLFEYVDQPIYSTGVGLLHYGARRVVERQFERPERQGVTSLWNRVQSWFKGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKX5</accession>
    <name>B1KKX5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cell division protein FtsQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ftsQ</name>
        <name evidence="10" type="ordered locus">Swoo_4531</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FtsQ/DivIB family. FtsQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4531"/>
    <dbReference type="EnsemblBacteria" id="ACA88781">
        <property type="protein sequence ID" value="ACA88781"/>
        <property type="gene ID" value="Swoo_4531"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4531"/>
    <dbReference type="eggNOG" id="COG1589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064041_2_0_6"/>
    <dbReference type="OMA" id="MARIQRF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00911">
        <property type="entry name" value="FtsQ_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005548">
        <property type="entry name" value="Cell_div_FtsQ/DivIB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026579">
        <property type="entry name" value="FtsQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045335">
        <property type="entry name" value="FtsQ_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35851">
        <property type="entry name" value="PTHR35851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03799">
        <property type="entry name" value="FtsQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="POTRA" evidence="9">
        <location>
            <begin position="16"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="218" mass="24551" checksum="54A578A1714BBFBA" modified="2008-04-29" version="1">MAAWKLNLVVNDADALPIEAVAIKGERDKTSDEEIQAALRDLMQRSFFSADVNQVQAALEALPWVYQASVRREWPAKLKVYLVEQQVVAHWNGDAWLNIHGQVFDAPKRESVGTLPLLAGPEGQSKLVLTTFRQLSELLKINGFNLHSLSLSPRHAWHASLDNGIMLELGREDKMARIQRFINVYPTLEKQSKSVAKVDLRYDTGLAVGWKNAQEESH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY0</accession>
    <name>MRAY_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="1">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mraY</name>
        <name type="ordered locus">Swoo_4536</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327112.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKY0"/>
    <dbReference type="SMR" id="B1KKY0"/>
    <dbReference type="STRING" id="392500.Swoo_4536"/>
    <dbReference type="EnsemblBacteria" id="ACA88786">
        <property type="protein sequence ID" value="ACA88786"/>
        <property type="gene ID" value="Swoo_4536"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4536"/>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023982_0_0_6"/>
    <dbReference type="OMA" id="LMSPLHH"/>
    <dbReference type="OrthoDB" id="1151822at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000090672" description="Phospho-N-acetylmuramoyl-pentapeptide-transferase">
        <location>
            <begin position="1"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <sequence length="360" mass="39863" checksum="BD69A6B22C52F456" modified="2008-04-29" version="1">MLVYLAEYLTQFYTGFNVFSYVTFRAILGLMTALMFSLWWGPKMIERLQMLQIGQIVRNDGPESHFSKRGTPTMGGILILAGVFISVLLWGDLGSRYVWVVLFVLASFGLIGFIDDYRKVVRKDTKGLIAKWKYILQSLAALVIAFYLYASADMTGETQLVVPFFKDIMPQLGGFFIVLAYFTIVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLSGHVQFANYLHLPYLPGAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLSLGAALGAIAVLVRQEILLVIMGGVFVMETVSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLFLVLLGLATLKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL21</accession>
    <name>B1KL21_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glyoxal + H2O = glycolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51672"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:34779"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322711.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="C56.975"/>
    <dbReference type="EnsemblBacteria" id="ACA84362">
        <property type="protein sequence ID" value="ACA84362"/>
        <property type="gene ID" value="Swoo_0061"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0061"/>
    <dbReference type="eggNOG" id="COG3155">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072952_1_0_6"/>
    <dbReference type="OMA" id="AQVQCFA"/>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026041">
        <property type="entry name" value="ElbB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10224:SF12">
        <property type="entry name" value="PTHR10224:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006320">
        <property type="entry name" value="Elb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="217" mass="23130" checksum="C0ED7EC64B279A72" modified="2008-04-29" version="1">MKKIAVLLSGAGVFDGSEIHESVLAMLALDKLGAEYQCFAPNINQMHVVNHLTGEVEAGEQRNVLIESARIARGEVKATDELDIAIFDGLIIPGGFGAAKNLCNFATNGSDCEVSPEVSVFIREFVEASKPVGFICIAPIMIPRLYGEGVNGTIGSDLETAQAFNLMGGIHQAAEVQEIIVDEERKVVSTPAYMLAGSISEANIGIEKLVKKVLELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL71</accession>
    <name>B1KL71_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322761.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0111"/>
    <dbReference type="EnsemblBacteria" id="ACA84412">
        <property type="protein sequence ID" value="ACA84412"/>
        <property type="gene ID" value="Swoo_0111"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0111"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_4_1_6"/>
    <dbReference type="OMA" id="SLAWTAH"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="167"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="34768" checksum="A6734E5857F8A906" modified="2008-04-29" version="1">MTVTNKDNLLGWTAAIAVAGIWGVTGVVSKPLSMAVDPMTLVFFRYVTAVIGLSVIFMITSRFTSLSKDLGSSLKIDKGDIAKIALCGIIGQGVFSLFNFLSLSHIGATENGVIQGMQPFATVFFGMMFMNFKMSKIQWGAFIASAVCIYAMSVGPTNQVENGSSVMGYVYVTCSMLSLAWTAHLRASLAEKYGSVVSMLYQYISVAVMGIIVVVAMDLDLSQINIILANPLLLGLLIFLGMGISGGSYLIQLYSFKKIGVEKATMALNLMPLVGYIVAVLTLGEQLHLSKTIIVSLIVVALYVFTKFEAKPEINKSLKPQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL92</accession>
    <name>B1KL92_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0132</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell inner membrane</location>
            <topology evidence="2 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322782.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0132"/>
    <dbReference type="EnsemblBacteria" id="ACA84433">
        <property type="protein sequence ID" value="ACA84433"/>
        <property type="gene ID" value="Swoo_0132"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0132"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_0_1_6"/>
    <dbReference type="OMA" id="LMYMSSS"/>
    <dbReference type="OrthoDB" id="91817at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="540"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="873"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="896"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="972"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1004"/>
            <end position="1026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1045" mass="112292" checksum="C76ED3BEE39ABC2B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE1</accession>
    <name>B1KLE1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324212.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1580"/>
    <dbReference type="EnsemblBacteria" id="ACA85866">
        <property type="protein sequence ID" value="ACA85866"/>
        <property type="gene ID" value="Swoo_1580"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1580"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045375_0_0_6"/>
    <dbReference type="OMA" id="TMCVREY"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="67"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="352" mass="39139" checksum="801BF30F719BF368" modified="2008-04-29" version="1">MSPILSKVTISPDKTLRDALELINSQALQVALVIDHNQHLLGVITDGDIRRGLLNNLSLDAIVTQVMNTNPRTAAPSTSKKKLLQLMQQHSILSIPLVKDNILVGLETLKSAQQQTHYANPVLIMAGGFGTRLKPLTDRCPKPMLKVGDKPLLEIALFNFIQAGFTNFYISTHYMPEQIQQHFGDGSQWNINITYVHEDTPLGTGGAVGLLPKSIPQLPTIVMNGDILTKVDFQLLLKFHDDNNADATMCVREYDYQIPYGVISGTGSRITGMIEKPIQRFFVNAGIYVINQEIIKSVAANTYIDMPTLLEQKIADEGHVLMFPIHEYWLDIGQMDDFKQAQADICAIGFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLF8</accession>
    <name>B1KLF8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Flagellar basal body rod protein FlgB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1597</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324229.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1597"/>
    <dbReference type="EnsemblBacteria" id="ACA85883">
        <property type="protein sequence ID" value="ACA85883"/>
        <property type="gene ID" value="Swoo_1597"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1597"/>
    <dbReference type="eggNOG" id="COG1815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125463_1_0_6"/>
    <dbReference type="OMA" id="GHMARND"/>
    <dbReference type="OrthoDB" id="1914857at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006300">
        <property type="entry name" value="FlgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30435:SF12">
        <property type="entry name" value="PTHR30435:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002889">
        <property type="entry name" value="Rod_FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01396">
        <property type="entry name" value="FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="132" mass="14559" checksum="E40C3E66ED741F34" modified="2008-04-29" version="1">MAISFDKALGVHQYTLGIRSQRAEVISSNIANADTPHYKARDIDFDKALQAATSQQRGLAMTGSDSKHFDLAALSEQHYGYRVPNQPDTGDGNTVDIQQEQSEFMQNALEYQMSLGFLDSKFSGLKKALKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG8</accession>
    <name>B1KLG8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar hook-associated protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1607</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324239.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1607"/>
    <dbReference type="EnsemblBacteria" id="ACA85893">
        <property type="protein sequence ID" value="ACA85893"/>
        <property type="gene ID" value="Swoo_1607"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1607"/>
    <dbReference type="eggNOG" id="COG1344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024437_5_1_6"/>
    <dbReference type="OMA" id="MRVTQGM"/>
    <dbReference type="OrthoDB" id="1788350at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013384">
        <property type="entry name" value="Flagell_FlgL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02550">
        <property type="entry name" value="flagell_flgL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flagellin_N" evidence="5">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="396" mass="42274" checksum="DC0EEC68AB734FE0" modified="2008-04-29" version="1">MRISTSQMFNQSINSVLDKQTATSKILDQLSSGKKVNTAGDDPVASVGIDNLNQQNALVDQFMKNIDYAKNRLGLSESKLGTAETLVASTREQVIRAINGGLSESERQMIADELKGTLEELVAVANTKDESGNYIFAGFETGKQPFAFDSAGNMIYSGDNGAREAVIASGVTIATNIPGDNAFMNAPSGLGDYSANYLASQVGEFSVDSAKITNPGTYVEDTYTFTMVGANLEVRDSSATLVTTEVGFDPTNPISFNGMEVKLDGMPTAGDSFSITPQSEVSIFDTINQAISLLEDPNKVNTPQGVSELAQILNNIDSGVNQISIARSETGNSLKSIESYSTHHVDEKLVNSSTLSMLEDLDYASAITEFEKQQLALNAVSSVFSKVGSVSLFDYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLL5</accession>
    <name>B1KLL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325648.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3041"/>
    <dbReference type="EnsemblBacteria" id="ACA87312">
        <property type="protein sequence ID" value="ACA87312"/>
        <property type="gene ID" value="Swoo_3041"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3041"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_15_3_6"/>
    <dbReference type="OMA" id="ETTPWGQ"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07477">
        <property type="entry name" value="Peptidases_S8_Subtilisin_subset"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034202">
        <property type="entry name" value="Subtilisin_Carlsberg-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764639" evidence="6">
        <location>
            <begin position="27"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="7">
        <location>
            <begin position="688"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="807" mass="83869" checksum="0417439C111A8300" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ6</accession>
    <name>B1KLQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325689.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3082"/>
    <dbReference type="EnsemblBacteria" id="ACA87353">
        <property type="protein sequence ID" value="ACA87353"/>
        <property type="gene ID" value="Swoo_3082"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3082"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_0_6"/>
    <dbReference type="OMA" id="SICAGGF"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766793" evidence="5">
        <location>
            <begin position="32"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="53"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="376"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="965" mass="103110" checksum="F4B03A2508CF7730" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLR3</accession>
    <name>B1KLR3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0319 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325696.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3089"/>
    <dbReference type="EnsemblBacteria" id="ACA87360">
        <property type="protein sequence ID" value="ACA87360"/>
        <property type="gene ID" value="Swoo_3089"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3089"/>
    <dbReference type="eggNOG" id="COG3110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1155758_0_0_6"/>
    <dbReference type="OMA" id="FMSWAIK"/>
    <dbReference type="OrthoDB" id="1877964at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018635">
        <property type="entry name" value="UPF0319"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38108">
        <property type="entry name" value="PTHR38108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09829">
        <property type="entry name" value="DUF2057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766797" evidence="2">
        <location>
            <begin position="22"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="24256" checksum="0ABA70E1E4FAAB03" modified="2008-04-29" version="1" precursor="true">MKSVMPITAIIALLGSSSALAANLNIPMAFEYLAVDGQKIESSLFNHKSDIELNNGPHKIAIRYHDMVQDDFSDGESFIKSSPFIVTLTVDGDHQYSLQASDGEVVKNPQKFAKSPSVVITRADSGTVDYQVKQTNFTEDSFVNSIFGGGNGQDISNVASAATGGVVATSSTITAPVSKPAPIDAVTGEKVNDAEHAEQMLQYWWLHADQKTRKEFMSWAIKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLR4</accession>
    <name>B1KLR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325697.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3090"/>
    <dbReference type="EnsemblBacteria" id="ACA87361">
        <property type="protein sequence ID" value="ACA87361"/>
        <property type="gene ID" value="Swoo_3090"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3090"/>
    <dbReference type="eggNOG" id="ENOG5033HKA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163439_0_0_6"/>
    <dbReference type="OMA" id="MADLCCL"/>
    <dbReference type="OrthoDB" id="1948023at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019657">
        <property type="entry name" value="ComFB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10719">
        <property type="entry name" value="ComFB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="10601" checksum="A66B5C5D8179FC55" modified="2008-04-29" version="1">MQLEVRNYYEVLLMELLSDEGLIDELPEEYLADLCCVTLNQLPVRYIRHLVDTHFFEDYAELEQMKSEIQTALEKSRAFLKSKLKQDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLZ8</accession>
    <name>B1KLZ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327203.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4628"/>
    <dbReference type="EnsemblBacteria" id="ACA88878">
        <property type="protein sequence ID" value="ACA88878"/>
        <property type="gene ID" value="Swoo_4628"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4628"/>
    <dbReference type="eggNOG" id="COG2894">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_801411_0_0_6"/>
    <dbReference type="OrthoDB" id="393887at1236"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="2">
        <location>
            <begin position="5"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="346" mass="39017" checksum="5C5659E7A0ABC5CD" modified="2008-04-29" version="1">MSSAKVINVVSGKGGTGKTLLTAVLADILGNEGYSVLVVDLDVFVRGLTSLLYFHRKETIQLTQEDKMSVAEYFIDKGDVEVSGKSKFSNERYRSFDVIPSVTRVDEVLNFKDIMPDDKQEAREIISSMLKRLDKGYDFIIFDSRAGYDELISATHFLSDITLCIEEEDDISKITSDNLVKQLEQDANVPIFRLTNKARGIRSENDLASRGIDYLGKVPFDMDVMESFGTAYFWDDISRTLYKSALARAWNNLSSKLQLNKPVTENRINLIGSERLEERLQFISLKDRVVFVYSLMITIIGLSYGIFGAKGLSVFWNEFGTSQSLALVIGISGVFSSMYLLLKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN7</accession>
    <name>B1KMN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325751.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3144"/>
    <dbReference type="EnsemblBacteria" id="ACA87415">
        <property type="protein sequence ID" value="ACA87415"/>
        <property type="gene ID" value="Swoo_3144"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3144"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127592_0_1_6"/>
    <dbReference type="OMA" id="IKEGECG"/>
    <dbReference type="OrthoDB" id="1864858at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14266" checksum="4908239A357F46EE" modified="2008-04-29" version="1">MLHQAPLVWGEIAVENMDRAVEFYGKHFGVSFRRETMNDMDMAILETEDKEAASIGLVKHEMMKPSAHGSVLYLHLSDKLTPLVEKIAQAGVNILLPVMPIKEGECGFIALFEDCEGNTVGLWSMESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMT9</accession>
    <name>B1KMT9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyisobutyrate dehydrogenase</fullName>
            <shortName evidence="5">HIBADH</shortName>
            <ecNumber evidence="5">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3197</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HIBADH-related family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325803.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3197"/>
    <dbReference type="EnsemblBacteria" id="ACA87467">
        <property type="protein sequence ID" value="ACA87467"/>
        <property type="gene ID" value="Swoo_3197"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3197"/>
    <dbReference type="eggNOG" id="COG2084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_6_0_6"/>
    <dbReference type="OMA" id="VTMIATC"/>
    <dbReference type="OrthoDB" id="1245550at2"/>
    <dbReference type="UniPathway" id="UPA00362"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011548">
        <property type="entry name" value="HIBADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01692">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="6">
        <location>
            <begin position="4"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="7">
        <location>
            <begin position="168"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU910714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="31196" checksum="C402DF7EE8815B7B" modified="2008-04-29" version="1">MTSVAFIGLGHMGAPMAANLVKAGLTVRVFDLVPQAMKSLTDLGAISSSSACGAAAGADVVITMLPAGKHVRSLYLGDDTNKGLIDVVAQGSLLIDCSTIDAMSAQTVAKSAAEKGLDFVDAPVSGGTAGAAAGTLTFICGGTDKAFDQAKAVLSNMGANILHAGGAGAGQIAKICNNMLLSVLMVGTSESLQMGIDHGLDPKVLSEIMKVSSGGNWTLDKYNPCPDVMPTVPSSNGYQGGFMVDLMVKDLGLSQEAALQSNSSTPMGALARSLYVNHARQGNGTRDFSSIFEQFTNSQQIKDKG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ2</accession>
    <name>RL10_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplJ</name>
        <name type="ordered locus">Swoo_4699</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327268.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMZ2"/>
    <dbReference type="STRING" id="392500.Swoo_4699"/>
    <dbReference type="EnsemblBacteria" id="ACA88949">
        <property type="protein sequence ID" value="ACA88949"/>
        <property type="gene ID" value="Swoo_4699"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4699"/>
    <dbReference type="eggNOG" id="COG0244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092227_0_2_6"/>
    <dbReference type="OMA" id="VRDQKQA"/>
    <dbReference type="OrthoDB" id="1470978at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002363">
        <property type="entry name" value="Ribosomal_L10_eubac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01109">
        <property type="entry name" value="RIBOSOMAL_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000121015" description="50S ribosomal protein L10">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <sequence length="166" mass="17642" checksum="FE72840E841846DF" modified="2008-04-29" version="1">MALGLEDKKAIVAEVNEAAKGALSAVVADSRGVTVGEMTGLRRAAREAGVYVKVVRNTLVKRAVAGTDFECLSDTFTGPTLIAFSNEHPGAAARLLKDFATAQEKFEIKAAAFEGEVIPAADIDRLAKLPTYDEALAQLMMTMKEASAGKFVRLLAALRDQKEEAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNA0</accession>
    <name>PUR9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="1">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">IMP cyclohydrolase</fullName>
                <ecNumber evidence="1">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="1">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="1">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">purH</name>
        <name type="ordered locus">Swoo_0296</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="1"/>
    <dbReference type="EC" id="3.5.4.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322946.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNA0"/>
    <dbReference type="SMR" id="B1KNA0"/>
    <dbReference type="STRING" id="392500.Swoo_0296"/>
    <dbReference type="EnsemblBacteria" id="ACA84597">
        <property type="protein sequence ID" value="ACA84597"/>
        <property type="gene ID" value="Swoo_0296"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0296"/>
    <dbReference type="eggNOG" id="COG0138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016316_5_2_6"/>
    <dbReference type="OMA" id="WRVAKFV"/>
    <dbReference type="OrthoDB" id="1049662at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000096096" description="Bifunctional purine biosynthesis protein PurH">
        <location>
            <begin position="1"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01202"/>
        </source>
    </evidence>
    <sequence length="535" mass="57881" checksum="4446705B9A63A128" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU4</accession>
    <name>B1KNU4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ordered locus">Swoo_3282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325888.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3282"/>
    <dbReference type="MEROPS" id="M24.001"/>
    <dbReference type="EnsemblBacteria" id="ACA87552">
        <property type="protein sequence ID" value="ACA87552"/>
        <property type="gene ID" value="Swoo_3282"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3282"/>
    <dbReference type="eggNOG" id="COG0024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_0_0_6"/>
    <dbReference type="OMA" id="GDHAYTF"/>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="12"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="265" mass="29339" checksum="BAA0D7114BF71F0B" modified="2008-04-29" version="1">MSIVIKTAEEIEKMRAAGKLASEVLEMVAPFVKVGVTTNELNEICAKFTEENGAISAPLDYHGFPKSICTSVNDVICHGIPNDRPLKDGDIVNLDITVIKDGYHGDTSKMFLIGDVSAKDMRLCRVAQESLYASIKKVRPGMKLGEIGTIVEKFVKGKKTGLEKYSIVKDYCGHGIGAGFHEEPQVMHYKNNDKTVLRPGMCFTIEPMINAGRHTCILDKEDNWTVTTSDGKKSAQWEHTLLVTKTGVEVLTLRAEEDFPRIINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX9</accession>
    <name>B1KNX9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327327.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4761"/>
    <dbReference type="EnsemblBacteria" id="ACA89010">
        <property type="protein sequence ID" value="ACA89010"/>
        <property type="gene ID" value="Swoo_4761"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4761"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_0_1_6"/>
    <dbReference type="OMA" id="KESANNQ"/>
    <dbReference type="OrthoDB" id="1930882at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="95"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="280" mass="30802" checksum="24689C8226CFD8AB" modified="2008-04-29" version="1">MASLLQKLKGEPQGKRFTSSLQDNFEGSGFHLLLFAVFVLHLLTINEASNLSVFNFINGLSPSIPAWLQASVTDMGNGVTLGAVILCYLVSRPELCCRVVVAAVLSLVMVPLLKQYFDAPRPAVILDYLNIIGEVRHEHSFPSGHAATAFLLAGIIFLSTSKHWLKGVVVVAAAFVAGSRIMVGAHWPEDVVMGAFVGLLCAYGAVKFVPLIVLSSSVRVKLYLVLFATIVISEFKNGDDFPQYWQVQVIRWSFILLSGLLILRFWLRSFPPNLLKNQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP06</accession>
    <name>B1KP06_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdenum ABC transporter, periplasmic molybdate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein ModA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4788"/>
    <dbReference type="EnsemblBacteria" id="ACA89037">
        <property type="protein sequence ID" value="ACA89037"/>
        <property type="gene ID" value="Swoo_4788"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4788"/>
    <dbReference type="eggNOG" id="COG0725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065520_1_0_6"/>
    <dbReference type="OMA" id="DITRPKK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030973">
        <property type="term" value="F:molybdate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13539">
        <property type="entry name" value="PBP2_AvModA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044084">
        <property type="entry name" value="AvModA-like_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005950">
        <property type="entry name" value="ModA"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004846">
        <property type="entry name" value="ModA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01256">
        <property type="entry name" value="modA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005661819" evidence="4">
        <location>
            <begin position="29"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="28723" checksum="E236EAC030507442" modified="2008-04-29" version="1" precursor="true">MIRLKRGLGLALASIILVFGLSVMQAKAADVPAIAAASNIKFALDELSSAFTQDTGLKVRLSYGSSGNFVAQIKHGAPFQMFLSADERYIEQLAKSGGTLDDGVLYAVGRLAIAAPKNSPLQLDPELKGLKRLIDSGELKRFAIANPDHAPYGERARFLLKGFGLWESITPALIYGENVSQAAQFAVSGSTQGGIIALSLAIAPQFQKLGRYKALPESLHEPIYQRMVLLNSAGSTAKAFYQYLQTDKARQVFSDFGFGLPPGVAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP88</accession>
    <name>B1KP88_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323007.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84658">
        <property type="protein sequence ID" value="ACA84658"/>
        <property type="gene ID" value="Swoo_0358"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0358"/>
    <dbReference type="eggNOG" id="ENOG5031PN4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_539568_0_0_6"/>
    <dbReference type="OrthoDB" id="92173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765100" evidence="1">
        <location>
            <begin position="21"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="505" mass="56448" checksum="603626149799117A" modified="2008-04-29" version="1" precursor="true">MKYPTIALALLLLLPACSQQHEPDIVEFKAQPGDSARYWMKTKSNINLKNIEIDQTSLALLHYQIDQVDDKILKFSVIPELMQFSGNRNNFHSARPTQRQQELQQLMSAGFDITLDPNTGELLNMSGKNAKIWQKMLQKSGEGFIDSIKNSLNSPGFVKQIPAKVGEKLPVTEVGIHDAVLQVDKVTDEQLTLLINSANEQTKLFGKVILSRDNGWIEKLALISVMPMESMGIQGTAHHSILMHRLNSNKLPSFIADLEQLIENDYWFELSKPNEIVTQHVEPTADELFKFTQGELLDNGNTFYTKLLLTDGEITPAGELWFTNMRASSSLQPVLDIKLMPTQPSMIMPAEDGVVVEQGFLPLGWLAKGDLAKIDKITATAHYQPAQLKTYSFPWSPDKTVTHKMGSLSLTISPLSGTTDKYAVDIFPTGNEFLMPIFDGIDGEVSYVAPNVGPDWLTYDDKFTASLNQSRILLKVTNAADTVTFYINQLAAEPAFEQQVEWTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP91</accession>
    <name>B1KP91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323010.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0361"/>
    <dbReference type="EnsemblBacteria" id="ACA84661">
        <property type="protein sequence ID" value="ACA84661"/>
        <property type="gene ID" value="Swoo_0361"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0361"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077604_0_0_6"/>
    <dbReference type="OMA" id="GWCLTHK"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="143"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="28274" checksum="087CBF7F4D3756CA" modified="2008-04-29" version="1">MSWDKENTFLNLVEVEQVISMFDLLPGVLFWIKDKNHNFVHANQAFIEHKEVRGLNQILGKNDYDFSPPHLAKQFIRDDKKILAGQTVTERLEMNMTQAGDPAWYATSKRPLSNQAGEIIGSYGITRHLQKQAMALSGVDAIKAPVDFVREHYSRHLAIEELAEVAHLSVSALERRFKKYLTKTPKQFINEVRLENARRLLVETDMPISQVGDATGFTDHSYFSKQFRLFFGELPSEFRKNYRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPB5</accession>
    <name>B1KPB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0386"/>
    <dbReference type="EnsemblBacteria" id="ACA84685">
        <property type="protein sequence ID" value="ACA84685"/>
        <property type="gene ID" value="Swoo_0386"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0386"/>
    <dbReference type="eggNOG" id="ENOG502Z8PF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117646_0_0_6"/>
    <dbReference type="OMA" id="VMHVREC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767268" evidence="1">
        <location>
            <begin position="22"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="192" mass="21415" checksum="64909EC5C9E4BDBE" modified="2008-04-29" version="1" precursor="true">MKKYPQILALSATCIALPAAAITAEQSAFFDSIAAHCGKAYEGTVIGATSADSSFSGKKLVMHVRECSDNELKVPFHVGDDHSRTWVITKTQHGLHLAHDHRHKDGSEDKVTMYGGMTAMMGSATEQSFPVDAYSINNFRENGLDVSVTNVWHMYIKPTEFTYRLTRENRDFRVDFDLTKPVDLPPVPWGHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD7</accession>
    <name>B1KPD7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323056.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0408"/>
    <dbReference type="EnsemblBacteria" id="ACA84707">
        <property type="protein sequence ID" value="ACA84707"/>
        <property type="gene ID" value="Swoo_0408"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0408"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054727_0_1_6"/>
    <dbReference type="OMA" id="DYPFMKR"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="89"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="307" mass="35428" checksum="5980AF2878526439" modified="2008-04-29" version="1" precursor="true">MLNFLPASLLYLMSSLLLVINTTVWAGLISIGGIIKLFVPFTAGRNLLTKIMNRFMWAWATCNGGILYLLADIEWDIQGLENLDKNSWYLLISNHLSGFDIAVQTYVLRNNIPMLKFFLKRELMFVPFLGLGCWALDMPFMSRTSPAKLKKNPKLKGKDLISTRRACEKFKTMPTSIINYVEGSRFTEEKRVRQDSPYRYLLRPKAGGIAFTLSAMGEQFTHLLNCTLVYPEAQSDPLSEVMHGKIKKIIVKIEVLPVPQVDNKRYFSEAPYRVEFQRWLNQLWEEKDEQIHQVMLEHGVAKEDKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPF1</accession>
    <name>B1KPF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323070.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0423"/>
    <dbReference type="EnsemblBacteria" id="ACA84721">
        <property type="protein sequence ID" value="ACA84721"/>
        <property type="gene ID" value="Swoo_0423"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0423"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_323610_0_0_6"/>
    <dbReference type="OMA" id="WNTTINQ"/>
    <dbReference type="OrthoDB" id="299730at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="809" mass="87562" checksum="CF005F42D51E4157" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPF2</accession>
    <name>B1KPF2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323071.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0424"/>
    <dbReference type="EnsemblBacteria" id="ACA84722">
        <property type="protein sequence ID" value="ACA84722"/>
        <property type="gene ID" value="Swoo_0424"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0424"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070658_0_0_6"/>
    <dbReference type="OMA" id="CPMNIEA"/>
    <dbReference type="OrthoDB" id="1512459at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="25221" checksum="9C2B7C8D4659A56E" modified="2008-04-29" version="1">MELYIGNKNYSSWSLRAWLMLEKSGIEFNEIKLKLFTDSFYQQLKEISPNLKVPALIDNDIKVWDSLAICEYINDAYMSGSAWPENLSQKAKARSFACEMHSGFNALRNELPMNIRATRCIQLSEAAKKDIQRIDTIWSQQMDEFDTGKTGSWLFGTWSITDMMFAPVVMRFHTYGVAVSDSSRRYMKHLTQSPEMQKWIAAALEETEIVNEDEAGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH9</accession>
    <name>B1KPH9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324478.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1848"/>
    <dbReference type="EnsemblBacteria" id="ACA86132">
        <property type="protein sequence ID" value="ACA86132"/>
        <property type="gene ID" value="Swoo_1848"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1848"/>
    <dbReference type="eggNOG" id="COG3746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043009_1_0_6"/>
    <dbReference type="OMA" id="RNDPYVG"/>
    <dbReference type="OrthoDB" id="493106at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767535" evidence="1">
        <location>
            <begin position="20"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="406" mass="45113" checksum="8A1B68D7B7125451" modified="2008-04-29" version="1" precursor="true">MIRKTLLASCIAMMLNASANGATVDEEIAALKARIDQLESEKVAPKSEVEEKKDNSIKFGGAARFQYSYEDYSDSNKDRGGDLDFDLFRIDVDGNIGDILFSAQYRWFQYMNVIHHAWVGYNFDDTQQGKIGVTQVPFGILTYASNSYFFSSNFYLGLEDDYDLGLNYTYKTDANRLDLAFYKNDELGGLDGYVSDRSDRYAYDVVGVRLPGEGIYDVPTLEAAESNTFNARYVHNLTFNDVAVELGASAQAGELDIAGAQDGDRFAAAIHGVVNYNRWNLKLQVTGYEYDVDGMDVEQMVVGAYHFYDSIPAEATTYIGNLAYSLPVSIGPISNLTFYNDYSLVTDKSADLEDTFMNVTGMAITAGGLYTYVDFVVAENQPFIGGSMVGNGEVNKRVNINFGYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPI0</accession>
    <name>B1KPI0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324479.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1849"/>
    <dbReference type="EnsemblBacteria" id="ACA86133">
        <property type="protein sequence ID" value="ACA86133"/>
        <property type="gene ID" value="Swoo_1849"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1849"/>
    <dbReference type="eggNOG" id="ENOG5031P0W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_195346_0_0_6"/>
    <dbReference type="OMA" id="CNELNIH"/>
    <dbReference type="OrthoDB" id="2060803at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="81" mass="9133" checksum="0FC4B2C023176F6C" modified="2008-04-29" version="1">MNLNNPPVAFTITRLNTSQGIIKATGEWNSDSLTMTENKLLIFTLDIMGTDGWVALDLTQSKTKMLLDELNDEVLLHLQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM7</accession>
    <name>B1KPM7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324526.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1896"/>
    <dbReference type="EnsemblBacteria" id="ACA86180">
        <property type="protein sequence ID" value="ACA86180"/>
        <property type="gene ID" value="Swoo_1896"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1896"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_34_9_6"/>
    <dbReference type="OMA" id="RLWILND"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="151" mass="17061" checksum="37BF4F0F9C462ECC" modified="2008-04-29" version="1">MDSRIIQGRLEDVDVISQLFNEYRQFYGQADDLPLARSFIAERLSDNSSIIFLAIDSHDLGLGFVQLYPGFSSISTKPVLNLNDLFVTKHARCVGLGVKLMKLVIQYARDHGISKLVLETQEANQPARSLYTSLGFEVDNDFLTYSLDIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPP4</accession>
    <name>B1KPP4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324543.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1913"/>
    <dbReference type="EnsemblBacteria" id="ACA86197">
        <property type="protein sequence ID" value="ACA86197"/>
        <property type="gene ID" value="Swoo_1913"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1913"/>
    <dbReference type="eggNOG" id="ENOG5032Y6T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183514_0_0_6"/>
    <dbReference type="OMA" id="AGCTPRI"/>
    <dbReference type="OrthoDB" id="2019404at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025985">
        <property type="entry name" value="YnbE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13617">
        <property type="entry name" value="Lipoprotein_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="66" mass="7521" checksum="97CDF2CB2702D5DF" modified="2008-04-29" version="1" precursor="true">MKKLQIQRITLSAITALLLLTGCTPTVKIEPPDKPIVINLNVKIEHEIRIKVDKELDELLTNDELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPU9</accession>
    <name>B1KPU9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325967.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3363"/>
    <dbReference type="EnsemblBacteria" id="ACA87632">
        <property type="protein sequence ID" value="ACA87632"/>
        <property type="gene ID" value="Swoo_3363"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3363"/>
    <dbReference type="eggNOG" id="ENOG5032RZ1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174786_0_0_6"/>
    <dbReference type="OMA" id="PAYKMIG"/>
    <dbReference type="OrthoDB" id="1926934at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9180" checksum="CC2CC3F8CA1E3166" modified="2008-04-29" version="1">MAKPNKKGPTRTVDIFCAKCKTQLFKYRKGGKGALVKCFKERIVEDHTQTPCICPGCGQEFARDTLVRGTPSLKMIGGKVSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPX0</accession>
    <name>B1KPX0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325988.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3385"/>
    <dbReference type="EnsemblBacteria" id="ACA87653">
        <property type="protein sequence ID" value="ACA87653"/>
        <property type="gene ID" value="Swoo_3385"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3385"/>
    <dbReference type="eggNOG" id="COG2706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_590374_0_0_6"/>
    <dbReference type="OMA" id="QNDDTVA"/>
    <dbReference type="OrthoDB" id="1419449at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="463" mass="49488" checksum="2CD44FA1D11E9858" modified="2008-04-29" version="1" precursor="true">MGIDKILLTSSIVTLATLFGPQAKADIITLNIEGEGSVSAAEASITCNESCVIENDLAKNTLIASPTENWQFTGWTGQQCDSGNEVFINEQSSRLSAVSGGAKTLRSADINGDGAEDLAAISLFDGTVITLINDGSGAFTKKTVEEGLSYPSSLDFYDWDSDGDDDLIVSVYGQSKLKLYSNDGNGDFSFNRDLLLEGTKPYAIAITDLNNDQQADLIVSSFSADISGDLFQLVTSIKSPKTSLFTLQDGEFVLEKTLSENAAITLDVSKSVDSNEFLVIAAEIVTGETVLYKTDESSTTRTVVDTRPASYGAAFGDIDNNGTVDILAAYYRPSVLGLYYNKGDNTFTDMQAITKPSEGVTATVIADLNSDGYQDVATGEFNNQRFYYFATNSYKDCIVKQGSDISLTAQFAQTSNPTPPSTPAPEEDSSSGGGALSWYSLLCALIVALGLTHSRQSRVQRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ09</accession>
    <name>B1KQ09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HI0933 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4873</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327439.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4873"/>
    <dbReference type="EnsemblBacteria" id="ACA89122">
        <property type="protein sequence ID" value="ACA89122"/>
        <property type="gene ID" value="Swoo_4873"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4873"/>
    <dbReference type="eggNOG" id="COG2081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025174_2_0_6"/>
    <dbReference type="OMA" id="RCNFTNM"/>
    <dbReference type="OrthoDB" id="1513550at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="394" mass="43044" checksum="CF44C4AB185C8BBB" modified="2008-04-29" version="1" precursor="true">MKHHDVIIIGAGAAGLMCAATAGYRGRDVLVLDNAKQAGRKILISGGGRCNFTNQKVEPNNFICSNNHFVKSALARYRSSDFIELVERHGIEYHERDHGQLFCNDSAKEIVTMLMTECEWAGAKVKLRTEINAIVKLESGQFQLMTDKGEFVCDSLVIATGGLSMPKLGASPFGYHLAEQFGLKVLPTHAGLVPFTWHSDQKIKFEPLSGIAVPSTITAKDGTQFSEALLFTHRGLSGPAILQISNFWKPGETISINLLPGIDVRAAIGLILANHPKQNLRNSLSHWLPKRLVEALFEETLLNKSMNQLIHSELEQVAVSLESWEILMNGTEGYRTAEVTLGGVDTDELSSKTMEAKTVSGLFFIGEVMDVSGWLGGFNFQWAWSSGVAAGQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ19</accession>
    <name>B1KQ19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327449.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4883"/>
    <dbReference type="EnsemblBacteria" id="ACA89132">
        <property type="protein sequence ID" value="ACA89132"/>
        <property type="gene ID" value="Swoo_4883"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4883"/>
    <dbReference type="HOGENOM" id="CLU_2939272_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="60" mass="6816" checksum="F3949497A8C2F5BF" modified="2008-04-29" version="1">MFVGEYSDSCEFTKQSWVGLALIKRRTRVPSARETGRLSLIKSPNISMDGVYAKNCLEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA9</accession>
    <name>B1KQA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323113.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0466"/>
    <dbReference type="EnsemblBacteria" id="ACA84764">
        <property type="protein sequence ID" value="ACA84764"/>
        <property type="gene ID" value="Swoo_0466"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0466"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_2_6"/>
    <dbReference type="OMA" id="NVYLGQY"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="55"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="372" mass="40774" checksum="37476D3960089D90" modified="2008-04-29" version="1" precursor="true">MKKWTLMMLIIALLAFGSVIGFNIMVKGKIADAIANMPEPESPVTALALTPQSWQPTIDAIGFVEPNQGVTIANELSGVISNINFENGSEVQDGQSLIVLDSAVEQANLKSKMVQLPAAEADYQRLTRLYKKNSVSKQDLDNSQSKYLALKADIESLKATIDRRQIDAPFAGLVGIRSVNLGEYLQAGTDIVRLEDISTMKIRFTVPQTQLPRISNGQTIHVYVDAYPDHPFEGKISAIEPAVFYQSGLIQIQATIPNIDAKLRSGMFARVAVLLPEMTEQFVLPQTAINFTLYGNSIYLIHESQEEGETVKRVQQINVEVLERNGNNALVKGHLAANDLVVTSGQVRLSNNSKVKVTEDDALTPPATMPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ7</accession>
    <name>B1KQJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5'-Nucleotidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1952</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324582.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1952"/>
    <dbReference type="EnsemblBacteria" id="ACA86236">
        <property type="protein sequence ID" value="ACA86236"/>
        <property type="gene ID" value="Swoo_1952"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1952"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_7_0_6"/>
    <dbReference type="OMA" id="HYADGQN"/>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005122593" evidence="2">
        <location>
            <begin position="17"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="45"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="4">
        <location>
            <begin position="370"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="569" mass="60837" checksum="D412CA5BBEAAEEA1" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR0</accession>
    <name>B1KQR0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3398"/>
    <dbReference type="EnsemblBacteria" id="ACA87666">
        <property type="protein sequence ID" value="ACA87666"/>
        <property type="gene ID" value="Swoo_3398"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3398"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_1_6"/>
    <dbReference type="OMA" id="EWVGETD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="166" mass="18771" checksum="A33820DE97704240" modified="2008-04-29" version="1">MIIAETERLILRRFTAEDKQAVFLLNSIPEILTYIPGEPMSSVTQAEQILNELVFPGYEKFGFGRWAVEHKADNKVIGFCGPTFVQEYNEVELGYRYLPDYWGTGIGFEAAQAALTKIPSFDIDHVIALILLGNRGSEALARKVGMTERERNTFMGHKVNVFHKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQW4</accession>
    <name>B1KQW4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate regulon transcriptional regulatory protein PhoB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3452</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326055.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3452"/>
    <dbReference type="EnsemblBacteria" id="ACA87720">
        <property type="protein sequence ID" value="ACA87720"/>
        <property type="gene ID" value="Swoo_3452"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3452"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="IDRVWGS"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011879">
        <property type="entry name" value="Sig_transdc_resp-reg_PhoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02154">
        <property type="entry name" value="PhoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="9">
        <location>
            <begin position="129"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="7">
        <location>
            <begin position="129"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="26338" checksum="9BC01B766761FD01" modified="2008-04-29" version="1">MTARILIVEDELAIREMLTFVLEQHGFVTSAAEDFDSALDLLTEPYPDLVLLDWMFPGGSGIQLAKRMRQDEFTRQIPIIMLTARGEEEDKVRGLEVGADDYMTKPFSPKELVARIKAVIRRSSPTSLEEPIDVQGLMLDPISHRVTVGEQVLEMGPTEFRLLHFFMTHPERVYSREQLLDNVWGTNVYVEDRTVDVHIRRLRKAIEPSNHDRLIQTVRGAGYRFSTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQX3</accession>
    <name>B1KQX3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326064.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3463"/>
    <dbReference type="EnsemblBacteria" id="ACA87729">
        <property type="protein sequence ID" value="ACA87729"/>
        <property type="gene ID" value="Swoo_3463"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3463"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_6"/>
    <dbReference type="OMA" id="EAQVMAM"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="26117" checksum="5373CA652276FFCA" modified="2008-04-29" version="1">MEKVALITGGGRGIGAATARYLADHGYSVGVNYKQNSETADALVAQLQAQGCRAQAFQADVSVESEVVAMFHELDLHLGKITALVNNAGILQPQMKVVDMSAERINRMLTNNVTSYFLCCREAVKRMALSKGGYGGAIVNVSSVASRVGGAGEYVDYAASKGAVDTLTIGLSLEVAADSIRVNSVRPGFIHTQMHADGGEPDRVKRLAPNIPMKRGGEPDEVAAAIAWLLSDEASYVTGTFVDIAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQY2</accession>
    <name>B1KQY2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326072.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3472"/>
    <dbReference type="EnsemblBacteria" id="ACA87738">
        <property type="protein sequence ID" value="ACA87738"/>
        <property type="gene ID" value="Swoo_3472"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3472"/>
    <dbReference type="eggNOG" id="ENOG5032BHD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_198377_0_0_6"/>
    <dbReference type="OMA" id="LAEGMEM"/>
    <dbReference type="OrthoDB" id="2065770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766971" evidence="1">
        <location>
            <begin position="22"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="75" mass="8212" checksum="96974712CA01B28C" modified="2008-04-29" version="1" precursor="true">MLNLKTVFVLAFLSTATSVQADEARIDTTDLHATISAELAEGMEVMQQDLTEDLNAMLNTKDKAEQAEVTVLRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR35</accession>
    <name>B1KR35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heavy metal efflux pump, CzcA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0556</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323200.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0556"/>
    <dbReference type="EnsemblBacteria" id="ACA84852">
        <property type="protein sequence ID" value="ACA84852"/>
        <property type="gene ID" value="Swoo_0556"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0556"/>
    <dbReference type="eggNOG" id="COG3696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="IVMMMRG"/>
    <dbReference type="OrthoDB" id="91817at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="569"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="905"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="932"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="961"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1016"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1044"/>
            <end position="1067"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1076" mass="115299" checksum="68FDE1172C85C0FB" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR52</accession>
    <name>B1KR52_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323217.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84869">
        <property type="protein sequence ID" value="ACA84869"/>
        <property type="gene ID" value="Swoo_0573"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0573"/>
    <dbReference type="HOGENOM" id="CLU_1685395_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="16360" checksum="E9060D1CDA1C69C5" modified="2008-04-29" version="1" precursor="true">MDKTSLTALGLVTFVGITALGYQIFTQDPSASLTPSQSSEQPAKTLAHISDPGRENVELATVSTLVKSDEGLTPVSTLPPESINLSTVNAPIEKAVSWSERERQNEAQTPPPQVADLVAEADPGPSAGKDLSRPQRPAVQAQRVAPVSRPAPTAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF0</accession>
    <name>B1KRF0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein, PqiA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2073</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PqiA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324702.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2073"/>
    <dbReference type="EnsemblBacteria" id="ACA86357">
        <property type="protein sequence ID" value="ACA86357"/>
        <property type="gene ID" value="Swoo_2073"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2073"/>
    <dbReference type="eggNOG" id="COG2995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041903_0_1_6"/>
    <dbReference type="OMA" id="PWMMADV"/>
    <dbReference type="OrthoDB" id="836803at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007498">
        <property type="entry name" value="PqiA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005219">
        <property type="entry name" value="PqiA-like_Ent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04403">
        <property type="entry name" value="PqiA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00155">
        <property type="entry name" value="pqiA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="406" mass="45224" checksum="0A21C08775EC85FA" modified="2008-04-29" version="1">MIIKNIESNVSGEREVCHECDLNVVIPSLRVNQKAVCPRCGYLLSAKRANSLERILALSITALIFLLASTLFDFISFKSSGLENNIKMLDSVGILIDSGYTALAIIELVTVFFIPAFVLLSLIYLLSFLINGRYPRKGHRLMEIIFKLIPWNMVEIFLVGTLVSLIKIISLADIILGPSFFAFILFSVSMTAALLHIDRRYLFQALDSRYTENTKASTSVKQGEPAVNESLVHHVDPSLSIQKTWALIITSILLYIPANTLPIMNTRLLGQDDPSTIIGGVILLWHHGSYPIAMVIFVASIMVPIAKILVLIWLNYSVQTNSMKLEHQRIILYRIAEFVGRWSMIDIFVVIILASLVQLGNTMSIVPGAATFAFSGVVVVTMLAAMSFEPKLIYNYKSAYENRSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF7</accession>
    <name>B1KRF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Conserved hypothetical amino acid ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2080"/>
    <dbReference type="EnsemblBacteria" id="ACA86364">
        <property type="protein sequence ID" value="ACA86364"/>
        <property type="gene ID" value="Swoo_2080"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2080"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088519_0_0_6"/>
    <dbReference type="OMA" id="YPFNRMI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767316" evidence="2">
        <location>
            <begin position="22"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="115"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="261" mass="29690" checksum="AE3EF31396F7B184" modified="2008-04-29" version="1" precursor="true">MIKLRHWFSLCGLLISSASHSALLNAKPLTYFVIAHQAEPFQIVDDTGQHQGIISDIITSILRGSRTNLIHKTYPFKRMLFMMEKENQSHWISYGSPAWKHSDGVEIQNNRLSQHPLFYVSHQLITDKDTDLHFSKIEDLFGQTLITLKGFSYPGLDSYLIKGQIKHIQVGSHEHALKALKTGRGVAFVAMKNRALYTLKTLGLEIDEYAFIDFSSVISSYPIHLSYSEGLPEPLIKQIETKIVELSSSGKITDIIRRYQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH5</accession>
    <name>B1KRH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324727.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2098"/>
    <dbReference type="EnsemblBacteria" id="ACA86382">
        <property type="protein sequence ID" value="ACA86382"/>
        <property type="gene ID" value="Swoo_2098"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2098"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_7_0_6"/>
    <dbReference type="OMA" id="DHCIFLD"/>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="7"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="47481" checksum="3C6E581BD21960D1" modified="2008-04-29" version="1">MNAAGPRIVIIGGGAGGLELATQLGHKLGRKNRAQIILVDKNRTHIWKPLLHEVATGSLDSDLDGVVYSAHAAKHGYQFQLGTFCGLNAETKQITMAPIADDAGHTILPERQISYDKLVIAIGSVSNDFNTPGVKENCFFLDSHQQANRFHDALLDCFTRVHQSESINQLNIAIVGGGATGVELSAELYHVTEMLKIYGLSKMTAEKLNIHLIEAGPRILPALPERIAGSARRELTKLGVNVMENTRISEATAQGFVTSEGEVIEANLMLWAAGVKAPDFIKSIELFELNRANQIMVKPSLLSTVDEAIYVIGDCCACQQADGSFVPPRAQSAHQMAECVEKNIINELNGEPREAYTYVDHGSLVNLSRFSTVGSLMGNLTKNSMFIEGRIARLVYISLYRMHQRAIHGSVKTLGLWFAEKVMRVVRPRMKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK6</accession>
    <name>B1KRK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3507</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3507"/>
    <dbReference type="EnsemblBacteria" id="ACA87771">
        <property type="protein sequence ID" value="ACA87771"/>
        <property type="gene ID" value="Swoo_3507"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3507"/>
    <dbReference type="eggNOG" id="COG2202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_20_6"/>
    <dbReference type="OMA" id="IVYTHMT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011620">
        <property type="entry name" value="Sig_transdc_His_kinase_LytS_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07694">
        <property type="entry name" value="5TM-5TMR_LYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="272"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="400"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="450"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="523"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="10">
        <location>
            <begin position="607"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="9">
        <location>
            <begin position="749"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1012" mass="114700" checksum="D3FF12362BF9C3EB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRP0</accession>
    <name>B1KRP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly PilZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326138.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3541"/>
    <dbReference type="EnsemblBacteria" id="ACA87805">
        <property type="protein sequence ID" value="ACA87805"/>
        <property type="gene ID" value="Swoo_3541"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3541"/>
    <dbReference type="eggNOG" id="ENOG502Z80T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017305_0_0_6"/>
    <dbReference type="OMA" id="DKSELPC"/>
    <dbReference type="OrthoDB" id="608311at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="2">
        <location>
            <begin position="143"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="PilZ" evidence="2">
        <location>
            <begin position="477"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="577"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="805" mass="92323" checksum="C688EEFF1ACD5D63" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRR0</accession>
    <name>IF2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">infB</name>
        <name type="ordered locus">Swoo_3561</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326158.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRR0"/>
    <dbReference type="SMR" id="B1KRR0"/>
    <dbReference type="STRING" id="392500.Swoo_3561"/>
    <dbReference type="EnsemblBacteria" id="ACA87825">
        <property type="protein sequence ID" value="ACA87825"/>
        <property type="gene ID" value="Swoo_3561"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3561"/>
    <dbReference type="eggNOG" id="COG0532">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006301_6_3_6"/>
    <dbReference type="OMA" id="NRDNRTG"/>
    <dbReference type="OrthoDB" id="347113at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013575">
        <property type="entry name" value="IF2_assoc_dom_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08364">
        <property type="entry name" value="IF2_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0396">Initiation factor</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000093825" description="Translation initiation factor IF-2">
        <location>
            <begin position="1"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="394"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="93"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="1">
        <location>
            <begin position="403"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="1">
        <location>
            <begin position="428"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="1">
        <location>
            <begin position="449"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="1">
        <location>
            <begin position="503"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="1">
        <location>
            <begin position="539"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="204"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="403"/>
            <end position="410"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="449"/>
            <end position="453"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="503"/>
            <end position="506"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="894" mass="95999" checksum="9F9CF55BB85A3D80" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX8</accession>
    <name>B1KCX8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322656.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0006"/>
    <dbReference type="EnsemblBacteria" id="ACA84307">
        <property type="protein sequence ID" value="ACA84307"/>
        <property type="gene ID" value="Swoo_0006"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0006"/>
    <dbReference type="eggNOG" id="ENOG5030DUI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078774_0_0_6"/>
    <dbReference type="OMA" id="WQFHLGS"/>
    <dbReference type="OrthoDB" id="1333443at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023977">
        <property type="entry name" value="CHP04052"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04052">
        <property type="entry name" value="AZL_007920_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="30997" checksum="8E39BBAECCC637F4" modified="2008-04-29" version="1" precursor="true">MRVVSNSRVGSIFERIKKLSIVLIVVILSCGCSPKPMTLPIKLMWGEQELNCNQALPELPQWRLENIQFYLSQFKNNGRPIYLVQDGHLTQQKNLALLGSDCRSDGQWQIVFEHTLEPGEFSFNLGVPFKQNHQAPLKSQSPLNQSDMFWTWQMGHKFFRLDLTKHESKKRETEPQTGWQFHLGSTGCKSASVMRAPTKECDHPNRPKFTLTYQGDNSLVLDLAPLLSETLNNQKITQDSCMSDPHTLICRELLPRIGINSSSEIWRWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD25</accession>
    <name>B1KD25_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-nitropropane dioxygenase NPD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326193.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3596"/>
    <dbReference type="EnsemblBacteria" id="ACA87860">
        <property type="protein sequence ID" value="ACA87860"/>
        <property type="gene ID" value="Swoo_3596"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3596"/>
    <dbReference type="eggNOG" id="COG2070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038732_5_1_6"/>
    <dbReference type="OMA" id="CDLICAQ"/>
    <dbReference type="OrthoDB" id="275153at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="12"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="341" mass="37558" checksum="3A43795F49BF6EE5" modified="2008-04-29" version="1">MKTRFLCQQLGTQYPIIQAPMAGGILSADFIAKVCEFGLLGSIPSGYLTLAQLDTLIQSVKSKTDKPFQVNLFVDHCEYPDKVAKPAEVIEIEKHLGIFTSLDCQLPKHPSASDIIDLVIAHQVPIISTTFGVLRAKDYQRYKDAGGQVMVTVNSLDEAHKVLSEANADMIVYQNALAGGHKGGFNDAEYDVEAVMLTLKRDYPYTQLIKSGGIVNQKDIVFALEKGFDGVQIGTGFLMTQESSASQTYKQALLGVCDDNQLMQTTSITGRQARGIVNELAMLELERSPLFPQQHYATKTIREHAKSHDLPQYQSLWAGNGAVNITSLPELEDYMFSLVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD45</accession>
    <name>B1KD45_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Na(+)-translocating NADH-quinone reductase subunit B</fullName>
            <shortName evidence="13">Na(+)-NQR subunit B</shortName>
            <shortName evidence="13">Na(+)-translocating NQR subunit B</shortName>
            <ecNumber evidence="13">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">NQR complex subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">NQR-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nqrB</name>
        <name evidence="15" type="ordered locus">Swoo_3616</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell inner membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the NqrB/RnfD family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326213.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3616"/>
    <dbReference type="EnsemblBacteria" id="ACA87880">
        <property type="protein sequence ID" value="ACA87880"/>
        <property type="gene ID" value="Swoo_3616"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3616"/>
    <dbReference type="eggNOG" id="COG1805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042020_1_1_6"/>
    <dbReference type="OMA" id="FNPAYPE"/>
    <dbReference type="OrthoDB" id="1654433at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00426">
        <property type="entry name" value="NqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010966">
        <property type="entry name" value="NqrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578">
        <property type="entry name" value="PTHR30578"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016055">
        <property type="entry name" value="NADH-UbQ_OxRdtase_B_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01937">
        <property type="entry name" value="nqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 13 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 13 14" id="KW-0288">FMN</keyword>
    <keyword evidence="11 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="4 13 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 13" id="KW-0813">Transport</keyword>
    <keyword evidence="13 15" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="13 14">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR016055-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA87880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="399" mass="43414" checksum="DDC735BD36115292" modified="2008-04-29" version="1" precursor="true">MSLNDFFKGIEPQFEKGGKYEKFYAIFEAAYTVFYTPGHVNKGSTHVRDNLDLKRMMIMVWACTFPAMFVGMYNVGLQAQDALAAGFATPDVWQVSLFGMFGTELTANSGIAALLWYGACFFLPIYAVTFAVGGIWEVLFAAVRGHEVNEGFFVTSVLFALTLPATIPLWMVALGITFGVVVAKEIFGGTGRNFLNPALAGRAFLFFAYPLSMSGDTTWVAADGYSGATALSQAAQGTLEYGFSQDWWDAFLGFIPGSVGEVSTLAILIGGAVIVYARIASWRIVAGVMVGMIAVSYLLNFIGSDTNPMFAMPWYWHLVLGGFAFGMMFMATDPVSASFTNSAKWGYGILIGAMAVFIRVINPAFPEGMMLAILFANLFAPLFDHFVVQANIKRRIARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG4</accession>
    <name>B1KDG4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0270 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323312.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0669"/>
    <dbReference type="EnsemblBacteria" id="ACA84965">
        <property type="protein sequence ID" value="ACA84965"/>
        <property type="gene ID" value="Swoo_0669"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0669"/>
    <dbReference type="eggNOG" id="COG3089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2571949_0_0_6"/>
    <dbReference type="OMA" id="ASERCKQ"/>
    <dbReference type="OrthoDB" id="1908383at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010648">
        <property type="entry name" value="UPF0270"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036685">
        <property type="entry name" value="YehU-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06794">
        <property type="entry name" value="UPF0270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118001">
        <property type="entry name" value="SSF118001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="78" mass="8903" checksum="9FC64F29BE201570" modified="2008-04-29" version="1">MLVPYDSLVQLPTETFEALIKEYLFTQLEDGSFSNTDEEGLQRAIAQCKQALKQGVLVVEYSEDDESIAIRQREQLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL0</accession>
    <name>B1KDL0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">OmpA/MotB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2123</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324752.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2123"/>
    <dbReference type="EnsemblBacteria" id="ACA86407">
        <property type="protein sequence ID" value="ACA86407"/>
        <property type="gene ID" value="Swoo_2123"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2123"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099038_0_0_6"/>
    <dbReference type="OMA" id="NDFFDRR"/>
    <dbReference type="OrthoDB" id="1843596at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027367">
        <property type="entry name" value="Gly-zipper_YMGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022511">
        <property type="entry name" value="PdsO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13441">
        <property type="entry name" value="Gly-zipper_YMGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03789">
        <property type="entry name" value="pdsO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764313" evidence="5">
        <location>
            <begin position="23"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="6">
        <location>
            <begin position="114"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="25668" checksum="5DFE4702D0DE72FF" modified="2008-04-29" version="1" precursor="true">MNKKIIALLVMSSLTLSNATHAQEQLDEREHNEELVGLTSGIVLGAVVGGPVGAIIGAFTGALLGKSVGDDSEIDAQHAKIAALSSDKQSLLVIADQYDEAQQQLAELKLAQDQKLTELAMGLNIQFKTGSSELAPHIKRQLDDLAYAITISPELRLDMTGYADRRGDSTYNQALSEQRVAEVKSYLVSQGVDESRLSYKAFGASAPLTEDQSFENDFFDRRVNIKLISNGSALAANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ2</accession>
    <name>B1KDQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324793.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2165"/>
    <dbReference type="EnsemblBacteria" id="ACA86449">
        <property type="protein sequence ID" value="ACA86449"/>
        <property type="gene ID" value="Swoo_2165"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2165"/>
    <dbReference type="eggNOG" id="ENOG502Z80B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028254_0_0_6"/>
    <dbReference type="OMA" id="WRYVKNN"/>
    <dbReference type="OrthoDB" id="761190at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="628"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="656" mass="72596" checksum="6F70179BF04DCEDF" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDT4</accession>
    <name>B1KDT4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin 4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2199"/>
    <dbReference type="EnsemblBacteria" id="ACA86481">
        <property type="protein sequence ID" value="ACA86481"/>
        <property type="gene ID" value="Swoo_2199"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2199"/>
    <dbReference type="eggNOG" id="COG2850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039125_0_0_6"/>
    <dbReference type="OMA" id="FPHDGFT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="JmjC_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="PTHR13096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="Cupin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="94"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="381" mass="43410" checksum="F88720612E35DEA2" modified="2008-04-29" version="1">MMQLELGELTPEQFLKEYWQKKPLVIRKGFSNFRDLLSPEEMAGLACDEMVESRRIYKEQGEWQAEFGPFDSYEHLGESGWTLVVQALNNWLPGAEQLIQCFDFIPRWRFDDVMVSYATPGGGVGPHIDLYDVFICQGSGRRRWRVGDRGEHREFAAHPALLHTEAFEPIIDVELLPGDILYLPPGYPHDGVTLEESMSFSVGYRTASAKDMVSALADHLIDNELGCEQIEDPDRVISLQSGRVDESDLARIKAQLLAKLDDRLISEFSGRYLTASKCELDLPEQSLGFQSTDILEMLKAQTLIRLGGLRVLYFDASVKQGLFYINGEEYQLSSALSDAIPFLCDQQQLSYSCIAPWLDSREFIEQLTLWVNAGFWYFEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV9</accession>
    <name>B1KDV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326293.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3701"/>
    <dbReference type="EnsemblBacteria" id="ACA87961">
        <property type="protein sequence ID" value="ACA87961"/>
        <property type="gene ID" value="Swoo_3701"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3701"/>
    <dbReference type="eggNOG" id="COG2888">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101353_1_0_6"/>
    <dbReference type="OMA" id="LVCEQCH"/>
    <dbReference type="OrthoDB" id="1667059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009912">
        <property type="entry name" value="DUF1451"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07295">
        <property type="entry name" value="DUF1451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="166" mass="18858" checksum="CBB81175AF776027" modified="2008-04-29" version="1">MSARSAELLSLYEALLAKVKADYLNDNSMTVKELFAVVTNGKEFLSLKEQAKEDELALVEQFLKRDIASYLQEKNDTDLSHSPTMITVENTVWHWLSGITDRSQIEWHEVLQDFKHQGHYQSGEIVGQGNMVCIHCGHEMKIEFPGVIPDCPECDESEFTREALAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDW7</accession>
    <name>B1KDW7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidoglycan glycosyltransferase MrdB</fullName>
            <shortName evidence="9">PGT</shortName>
            <ecNumber evidence="9">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cell elongation protein RodA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cell wall polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Peptidoglycan polymerase</fullName>
            <shortName evidence="9">PG polymerase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mrdB</name>
        <name evidence="9" type="synonym">rodA</name>
        <name evidence="10" type="ordered locus">Swoo_3709</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Peptidoglycan polymerase that is essential for cell wall elongation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SEDS family. MrdB/RodA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326301.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3709"/>
    <dbReference type="EnsemblBacteria" id="ACA87969">
        <property type="protein sequence ID" value="ACA87969"/>
        <property type="gene ID" value="Swoo_3709"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3709"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029243_2_2_6"/>
    <dbReference type="OMA" id="IFCTVGE"/>
    <dbReference type="OrthoDB" id="1133883at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02079">
        <property type="entry name" value="PGT_RodA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018365">
        <property type="entry name" value="Cell_cycle_FtsW-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011923">
        <property type="entry name" value="RodA/MrdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474:SF1">
        <property type="entry name" value="PTHR30474:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02210">
        <property type="entry name" value="rodA_shape"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00428">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="2 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="368" mass="40867" checksum="0B95764A6F5951F2" modified="2008-04-29" version="1" precursor="true">MSPQNHRPNIWQRMHIDLPLLLGILALMSFGLFVIYSAGGEDLALMERQLFRMGLSLFIMFVVAQINPEVLRRWAFPIYIAGIILLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAGVILLVPTLLIAKQPDLGTSILVAASGIFVLFLSGMSWRIVGGFIGSILAMLPVLWFFLMHDYQRTRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGMLGKGWLDGTQSQLEFLPERHTDFIFAVIGEEFGLIGSFLLLAIYLYVIGRGLVIASQAQTSFARLLAGSITLTFFVYIFVNIGMVSGLLPVVGVPLPLISYGGTSMLTLMTGFGILMSIHTHRRFIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE29</accession>
    <name>B1KE29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323362.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0720"/>
    <dbReference type="EnsemblBacteria" id="ACA85015">
        <property type="protein sequence ID" value="ACA85015"/>
        <property type="gene ID" value="Swoo_0720"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0720"/>
    <dbReference type="eggNOG" id="ENOG5032SWH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166932_0_0_6"/>
    <dbReference type="OMA" id="WQQNQKA"/>
    <dbReference type="OrthoDB" id="1931144at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="12615" checksum="CE56B498999E88F8" modified="2008-04-29" version="1">MTKPKHPLPEQWLQNQKAAKATQVAFDLDEQFQYSIRKAALDSGVSPSDQIRTILGLSVTKRPKRPRLTVSLSPEDYVQLAEKYQLSPQDQLEIKKRVLDDLIHFGDENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE66</accession>
    <name>B1KE66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323399.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0757"/>
    <dbReference type="EnsemblBacteria" id="ACA85052">
        <property type="protein sequence ID" value="ACA85052"/>
        <property type="gene ID" value="Swoo_0757"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0757"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1331181_0_0_6"/>
    <dbReference type="OMA" id="INTIKMH"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="138"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23673" checksum="6B5E356F60A8DAAB" modified="2008-04-29" version="1">MFDGEIFTPKLTENNLLLLKSTAGFLNLKVNQSKNLVNAWSNCQEKQKILLHFMSSVSNDIQNIEKSLLSDGFHIAICNKLSIDDEVSLIKLGFRASVSSDAPAHLLLETISKILKGNLYFSNEALSKFILNYQKQTLSEGQVLLITSTTKKEKEVLSLVCNGFSNEQVAHQLNVSINTIKMHMQNIYKKTNIRNRSHLLLAYNQGMEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEG2</accession>
    <name>B1KEG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">40-residue YVTN family beta-propeller repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324883.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2259"/>
    <dbReference type="EnsemblBacteria" id="ACA86540">
        <property type="protein sequence ID" value="ACA86540"/>
        <property type="gene ID" value="Swoo_2259"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2259"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009318_2_0_6"/>
    <dbReference type="OMA" id="GQRVWQM"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022456">
        <property type="entry name" value="PQQ_b_propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03866">
        <property type="entry name" value="PQQ_ABC_repeats"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764343" evidence="1">
        <location>
            <begin position="24"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="35764" checksum="EB9BCDA8FFF5D010" modified="2008-04-29" version="1" precursor="true">MKLAIIANPLVGISCLFALSLPAAELAYVTNEKDDDISVIDLASQKVIKRIPVGQRPRGIIFNHDKSLAYICASDSDTIQILDLATEEVIGELPSGEDPETIALHPDGKTIYTSNEDDALLTVIDIATRTVKTQIDVGVEPEGLAVSPDGKIVVVTSETTNMVHWINTETYENFDNTLVAARPRSAMFTQDNKHLWVSSEIGGELVVIDVATRKIVKTFTFEVNGIHSDRVQPVGIELSRDGRYAFVALGPANHLAVIDRKTLTIEKYLLVGRRVWQLAFNQDQSLLLTTNGVSGDVSVVDVENLKVTKSIKVGRYPWGVMIKEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEL6</accession>
    <name>B1KEL6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326363.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3772"/>
    <dbReference type="EnsemblBacteria" id="ACA88031">
        <property type="protein sequence ID" value="ACA88031"/>
        <property type="gene ID" value="Swoo_3772"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3772"/>
    <dbReference type="HOGENOM" id="CLU_962772_0_0_6"/>
    <dbReference type="OrthoDB" id="2133407at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="33569" checksum="985B3166A38ACA14" modified="2008-04-29" version="1">MNMIKRRKSSFYPVGSLENKRNYKEYFILEKDGSIVDKVFLDIIDPSRRELIICLHYMRHVVRNFYAEDVGINITSRDAPWDFGLELSTGEQANIEITSITDVTQNFKTHKSEERYTKWKNEKMIPFHELKKLSRLFSSSSLLREVESLEKNGFKNTDMVENPMYGESMTMFVGNMPESEVSLSEILKEAIDKKANKKHSEKEQTTLIIDNRAYLFEVNDFYLAAEELNAYCASLAFPEVWFYTGYFSDGDGNNAEFSFAPLKVTSQQSKILENMAESKNIDESGKYVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF16</accession>
    <name>B1KF16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0873</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323514.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0873"/>
    <dbReference type="EnsemblBacteria" id="ACA85167">
        <property type="protein sequence ID" value="ACA85167"/>
        <property type="gene ID" value="Swoo_0873"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0873"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_50_6"/>
    <dbReference type="OMA" id="GYYWSKP"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="28"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="102"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="184"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="4">
        <location>
            <begin position="332"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="311"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="583" mass="66065" checksum="77D817B29A814F35" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC3</accession>
    <name>B1KFC3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative orphan protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325006.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2385"/>
    <dbReference type="EnsemblBacteria" id="ACA86664">
        <property type="protein sequence ID" value="ACA86664"/>
        <property type="gene ID" value="Swoo_2385"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2385"/>
    <dbReference type="eggNOG" id="ENOG50331HC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150463_0_0_6"/>
    <dbReference type="OMA" id="DYVEEFC"/>
    <dbReference type="OrthoDB" id="2049123at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="116" mass="13548" checksum="B15F8C7CFFF8F0BA" modified="2008-04-29" version="1">MSTELPKEKKLTVLCRVEPGCLGPDGLDHIESFCRFSHQELKKIDSDFIKWLPLPRYDKSLAEMEYSVDSKLLSRDKASQYLAHFKCELDEFEEHFHDKLSTLINEFLANNKAKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFD5</accession>
    <name>B1KFD5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326440.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3852"/>
    <dbReference type="EnsemblBacteria" id="ACA88110">
        <property type="protein sequence ID" value="ACA88110"/>
        <property type="gene ID" value="Swoo_3852"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3852"/>
    <dbReference type="eggNOG" id="COG3014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035715_2_1_6"/>
    <dbReference type="OMA" id="FNRANER"/>
    <dbReference type="OrthoDB" id="1203790at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764378" evidence="1">
        <location>
            <begin position="25"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="457" mass="50878" checksum="A012536A4A53CE0A" modified="2008-04-29" version="1" precursor="true">MKLRSLSIVIAVTMLSGCAGLMHGQDTEKFNTYMSAGDFAGASQFALEKSGYNPEEKTVDDLLWAIEAGATLSYAGQFEKSISLLDASESMMKKEDQESLVNDASEVGLSMLGNDAMMAYEQTQYDGVMANSIKAWSFAFNNEHGDARVEWNRAEERQRRAAEYFAKQIKEQKDAEEGEETSEYVAKSVQSEETKKLLAKNGVTLEQWQPYKGYVNPYTTYSYGLNLLVNGKSKSDFQKAEDAFKRVYGLSQSKSVAEDIKLATSLRQGKKNAADGMVWVIFENGQSVVKEEFRIDLPVFLLSDDVSYTGIALPRLKERELAHKHIQIDGVKTETIADMDKIIGAEFEKQYPMILTREITRTVLKTVAQKQAMDSNEILGNLLAVAQVATTNADTRSFSSLPKEFQTTRLKKSGNSVKLKAGTHEILVELDTNAKRHIVYVKAISPLVAPTVRVINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM6</accession>
    <name>B1KFM6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coenzyme PQQ synthesis protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323539.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0898"/>
    <dbReference type="EnsemblBacteria" id="ACA85192">
        <property type="protein sequence ID" value="ACA85192"/>
        <property type="gene ID" value="Swoo_0898"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0898"/>
    <dbReference type="eggNOG" id="COG1235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_997296_0_0_6"/>
    <dbReference type="OMA" id="THAHIGH"/>
    <dbReference type="OrthoDB" id="1712770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="79"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="34938" checksum="6CCF2188A1D5C00F" modified="2008-04-29" version="1" precursor="true">MGLKGVALIITSIFMFISSALQAEEKSPYLYILGVAQDAGYPQTGCYAEHCMPGWNDLSLRRGAVSLGLIDPTSNKKYMFEATPNFPEQLYQLEKEAPNEQFELDGVFITHAHIGHYSGLMFLGREAMGADNTPVYVMPKMGQFLQNNGPWNQLIKYNNIELQPLKNNHSQKLGSVKVTPFIVPHRDEYSETVGYRIEGPSKTALFIPDIDKWSEWETNIVDAINTVDYALIDATFFADGELPGRDMSKIPHPFVSESMALFQALSSQQKQKVWFIHFNHSNPLINPDSKESKQVKASGFNIAKEGIRLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFP3</accession>
    <name>B1KFP3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0916</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323556.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0916"/>
    <dbReference type="EnsemblBacteria" id="ACA85209">
        <property type="protein sequence ID" value="ACA85209"/>
        <property type="gene ID" value="Swoo_0916"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0916"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_5_0_6"/>
    <dbReference type="OMA" id="EDCWFIA"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="16808" checksum="5C8D2DE4646A449B" modified="2008-04-29" version="1">MDTSFQRDQLDNQILSALMEEARTPFAELAKRFGVSAGTIHVRVEKMKQAGIITGAQITVDPKALGYDVCCFIGINLKSAGDYPAAISKLNALEEVVEAYYTTGNYSVFVKVMCQSIDGLQHVLINRIQSIDEIQSTETLISLQNPIVRAVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFR8</accession>
    <name>B1KFR8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-sorbosone dehydrogenase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323581.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85234">
        <property type="protein sequence ID" value="ACA85234"/>
        <property type="gene ID" value="Swoo_0941"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0941"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024435_3_1_6"/>
    <dbReference type="OMA" id="ETHHGWK"/>
    <dbReference type="OrthoDB" id="1150223at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSDH" evidence="1">
        <location>
            <begin position="170"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="361" mass="40191" checksum="48211994A32B1590" modified="2008-04-29" version="1" precursor="true">MRSLLIPIAILFSNISHSLPLEKITLPPDFKIELYAKGVDNARQMALGDKGTLFVGSRKEGKVYALIDNDGDYKADKVIDIASKLFMPSGIAYHQGDLYVAEVDKIWRYSNIEASLPSVPTPELVYGKLPNKSHHGWKFIAFGPDGKLYIPVGAPCNVCESELPFATILKLDTVTKNSKIVATGVRNSVGFDFHPKTGDLWFTDNGRDMMGDDLPDDELNHVSKEGQFFGFPYIHNDDIHDPKFTSPEKAKHNRKPALKLGAHVAALGMEFYQGKQFPAEYQNNIFIAEHGSWNRSKKVGYRIVRVVLEGDRVVNSEVFASGWLQGEESWGRPVSVLTLPDGSLLVSDDAADAIYRISYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG92</accession>
    <name>B1KG92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">2-polyprenyl-6-methoxyphenol 4-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3972</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326559.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3972"/>
    <dbReference type="EnsemblBacteria" id="ACA88229">
        <property type="protein sequence ID" value="ACA88229"/>
        <property type="gene ID" value="Swoo_3972"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3972"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_8_1_6"/>
    <dbReference type="OMA" id="KRWFARQ"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008681">
        <property type="term" value="F:2-octaprenyl-6-methoxyphenol hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011295">
        <property type="entry name" value="UbiH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01984">
        <property type="entry name" value="UbiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="8">
        <location>
            <begin position="14"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="416" mass="45529" checksum="FA60419573E47C59" modified="2008-04-29" version="1">MTAHTEQDTDLINVDVAIVGGAMAGATLALGLKGLADSLKRPLKIALIEAHRPNSEHPGFDARSIAIAHGSIFELTKLGLWPKLAHLGTPIENIHISDRGHMGMTELNADSFHLNYLGQVVELEQVGQVLFKLLDDADISLYCPNKLASVEAKVDAQLLTLDDGTRISTSLLVAADGVNSKVREAFKQPLEQVDFGQTALIANVETDKAHDNWAYERFTNTGPLAVLPMSSNQGCGRVSLVWALDPDQAKLLLSIPKPDFLRALQTAFGSRAGLFTSVGERYSYPLMLSYMPRPIYHRTVFIGNAAQTLHPIAGQGFNLGLRDLVSLLEVIKQALQDETQDKPVDLGSAQIAHAYLQSREQDRNSTITNIEFLVRGFSNEHWPLVAGRSLGLRLLSWFPPLKTPVARTAMGWKQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGF7</accession>
    <name>B1KGF7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5610 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323632.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0992"/>
    <dbReference type="EnsemblBacteria" id="ACA85285">
        <property type="protein sequence ID" value="ACA85285"/>
        <property type="gene ID" value="Swoo_0992"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0992"/>
    <dbReference type="eggNOG" id="ENOG5031M9J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098243_0_0_6"/>
    <dbReference type="OMA" id="MGPNATQ"/>
    <dbReference type="OrthoDB" id="1739644at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041651">
        <property type="entry name" value="DUF5610"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18433">
        <property type="entry name" value="DUF5610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5610" evidence="2">
        <location>
            <begin position="63"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="196" mass="21037" checksum="E6A7E292346C4070" modified="2008-04-29" version="1">MEIKNHGAEVSQAAKSNTQTTENHGKSVSEVATNKTAYASSKQLMNSAIISAQQEVSLSSSNEPLVLLYRAAIEAINEELAPSMGENALQTAYDNGVDTSPEATADRIVSFATNFFSLYQEQNSNMSFDEQLTSFMEIIGGAIDQGFDEAKDILNGLQVLEGDIADGVDQTYSLVQDGLLAFKESFNDADDSLTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGH7</accession>
    <name>B1KGH7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)</fullName>
            <ecNumber evidence="4">3.6.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ap4A hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diadenosine tetraphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1012</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24252"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.41"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Ap4A hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.41" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323652.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1012"/>
    <dbReference type="EnsemblBacteria" id="ACA85305">
        <property type="protein sequence ID" value="ACA85305"/>
        <property type="gene ID" value="Swoo_1012"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1012"/>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056184_2_0_6"/>
    <dbReference type="OMA" id="INAFTRM"/>
    <dbReference type="OrthoDB" id="900869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008803">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07422">
        <property type="entry name" value="MPP_ApaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004617">
        <property type="entry name" value="ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000903">
        <property type="entry name" value="B5n-ttraPtase_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00668">
        <property type="entry name" value="apaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="9">
        <location>
            <begin position="5"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="274" mass="30879" checksum="21BDD4BF8EC38FB3" modified="2008-04-29" version="1">MANYFVGDIQGCFDELTLLLSKVDFNPSQDQLWAVGDLVARGPGSLPTLQYFKALDGAANVSLGNHDLHLMAVHGKIKRANPKDKLEALLASSDIDSLIGWLRHQPLHQELPEHSLVMTHAGVPPHWDISTLRGESKRVTQALQAPDYQEALLEKMYTSGSNQWHSNMDELERKIYCINALTRMRFLHSDNSLDFDCKLSPAECKDPDLTPWFELEGKINKTHTLVFGHWAAVMGKVSSSRIKALDTGCCWGEYLTLWHLETDEKITQNKLKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGP0</accession>
    <name>B1KGP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1075</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323714.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1075"/>
    <dbReference type="EnsemblBacteria" id="ACA85368">
        <property type="protein sequence ID" value="ACA85368"/>
        <property type="gene ID" value="Swoo_1075"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1075"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_0_6"/>
    <dbReference type="OMA" id="YLTMEDV"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="284"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="443" mass="49404" checksum="B90D2DAEB2938A6D" modified="2008-04-29" version="1" precursor="true">MSFFDNAVIILFLIGTSCFFSMSEIALAASRKIRLRQMASDGDLRAEKVLMLQANPGNFFTVVQIGLNAVAIMGGIVGESAFTPYIHSFLAPWLSEPWLGKVSFFLSFVLVTSLFILMADLMPKRVAMAIPEKVALILVGPLLVSITVFKPLVWFFNSLASMLFRLLQIQTSRNDEVTSDDIYAVMDAGAEAGVLDKDEQLMMEKVFEMQTIPVTAAMTARESLSYFLLQDSEEEIKRKISEDPHSNFLVCDGQLDVIKGFVNAKKLLICVINGQSISLKNNELVESCFIIPDTLSLSESMEYFKNSRADFAVVINEYSLVVGIVTSKDLQDAVMGAWSLPESEEQIIARDDNSWLMDGVTPITDVMRALDIEDFPQDHNYETIAGFMMYMLRKIPKCTDSVTHSGFKFEVVDVDAYKVDQLLVTRLNAHPVTDISLIPEPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHI7</accession>
    <name>B1KHI7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325212.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86872">
        <property type="protein sequence ID" value="ACA86872"/>
        <property type="gene ID" value="Swoo_2595"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2595"/>
    <dbReference type="eggNOG" id="COG3148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066458_1_1_6"/>
    <dbReference type="OMA" id="QQGNLCT"/>
    <dbReference type="OrthoDB" id="1600710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039262">
        <property type="entry name" value="DTWD2/YfiP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392">
        <property type="entry name" value="PTHR21392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="5">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="168" mass="18898" checksum="2A45E56C16CBEF42" modified="2008-04-29" version="1">MKVILLTHEREVTRLTNTGGKALELFPHWCSRVIWSRVEADDGIVHLLSSNKAAVLFPKPVLSKETGDSMLQTPMEELSLYLNEIPETIIILDATWQEARKMIRQSPYLATASKYALTQGGDSQFNLRRNQIPGGLCTLECIIQLCHSAKMTEEALELEAAYIALNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHK4</accession>
    <name>B1KHK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lytic transglycosylase catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325229.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2612"/>
    <dbReference type="CAZy" id="CBM50">
        <property type="family name" value="Carbohydrate-Binding Module Family 50"/>
    </dbReference>
    <dbReference type="CAZy" id="GH23">
        <property type="family name" value="Glycoside Hydrolase Family 23"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86889">
        <property type="protein sequence ID" value="ACA86889"/>
        <property type="gene ID" value="Swoo_2612"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2612"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009520_1_4_6"/>
    <dbReference type="OMA" id="ARHMPTE"/>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="332"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="405"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="464"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="517" mass="57952" checksum="F441BEB7CD19FA33" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP7</accession>
    <name>B1KHP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325272.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86932">
        <property type="protein sequence ID" value="ACA86932"/>
        <property type="gene ID" value="Swoo_2656"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2656"/>
    <dbReference type="eggNOG" id="ENOG5032UMW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1987951_0_0_6"/>
    <dbReference type="OMA" id="PWFGIMG"/>
    <dbReference type="OrthoDB" id="1601701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16687" checksum="841A644F7AD911B0" modified="2008-04-29" version="1">MHKTITLSEYVKKRNGVALGASGSMTNMLKRSLGASSFYLFWQHWNPIWGYYLSRKVMKPLSQLFPIWLAIIMTFAVSGALHDLAITLVKWKLTTFFTPWFSLMGFIVLATKRLGISYREHHWLIRASINSSLIAICLVITRQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT0</accession>
    <name>B1KHT0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Porin Gram-negative type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326737.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4152"/>
    <dbReference type="EnsemblBacteria" id="ACA88408">
        <property type="protein sequence ID" value="ACA88408"/>
        <property type="gene ID" value="Swoo_4152"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4152"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038238_3_0_6"/>
    <dbReference type="OMA" id="NTTHRKL"/>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002299">
        <property type="entry name" value="Porin_Neis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00184">
        <property type="entry name" value="NEISSPPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767360" evidence="4">
        <location>
            <begin position="24"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="13"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="342" mass="37403" checksum="F30A85BB4960D660" modified="2008-04-29" version="1" precursor="true">MNKTLISTTLASMFTLTSFGALADGPNFYGRLDLAVTNSDTGATTQEKKDGTVIENNFSHIGVKGSETLTKGFDVIYQMEFQVENTSSNKDVFKARNTYLGLKTVAGTLLVGRNDTVFKQSEGGIDLFGNSNADIDRLVGGQTRSADGIWYYSPKIANAISINATYLMEDNHRDANGNVIDETQYAISAIMGDKKLKNQNYYLAAAYNTIGGIDAYRGVAQVKLGDFKIGGLFQNTESQTDSTQEGNSYFVNVAYNLNGINLKAEYGKDEAGFGKYYKNITADVRGTEIDVQVITLGADYKLTKSTLIYGHYAMYEGDHNTLAGKVSLEDDNIFTIGARYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY1</accession>
    <name>B1KHY1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-dihydrouridine(20/20a) synthase</fullName>
            <ecNumber evidence="6">1.3.1.91</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">U20-specific dihydrouridine synthase</fullName>
            <shortName evidence="6">U20-specific Dus</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-dihydrouridine synthase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dusA</name>
        <name evidence="10" type="ordered locus">Swoo_4203</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NAD(+) = H(+) + NADH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53340"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NADP(+) = H(+) + NADPH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53336"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NAD(+) = H(+) + NADH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53348"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NADP(+) = H(+) + NADPH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53344"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Dus family. DusA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.91" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326788.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4203"/>
    <dbReference type="EnsemblBacteria" id="ACA88459">
        <property type="protein sequence ID" value="ACA88459"/>
        <property type="gene ID" value="Swoo_4203"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4203"/>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_2_1_6"/>
    <dbReference type="OMA" id="LIYPYVD"/>
    <dbReference type="OrthoDB" id="1320183at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102264">
        <property type="term" value="F:tRNA-dihydrouridine20 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02041">
        <property type="entry name" value="DusA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004653">
        <property type="entry name" value="DusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907">
        <property type="entry name" value="PTHR42907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00742">
        <property type="entry name" value="yjbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="9">
        <location>
            <begin position="19"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 8">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="214"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="236"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="331" mass="37154" checksum="FBC5374C888D86E0" modified="2008-04-29" version="1">MSSQNTKSSVKPLNRTFSIAPMLDWTDRHYRYLARLMSAELLLYTEMVTTGAIIHGKGDYLAYNEEEHPLALQLGGSNPHDLAICAKQAVERGYDEINLNVGCPSDRVQSGRFGACLMAEPSLVAECVTAMRAVADIPVTVKTRIGIDEQDSYEFLTEFVETVRDAGCDTFIVHARKAWLQGLSPKENREIPPLDYDRVYQLKRDYPDLSISINGGVKSLEECKVHLVKLDGVMVGREAYQNPYILAKVDQQLCGLDKPVLSRDAVLEKFIPYIEKHLQAGGRLNHITRHMTGLFQGEVGSRIWRRYISENAHKPGSGIEVIEQARKNMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI01</accession>
    <name>B1KI01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323825.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1186"/>
    <dbReference type="EnsemblBacteria" id="ACA85479">
        <property type="protein sequence ID" value="ACA85479"/>
        <property type="gene ID" value="Swoo_1186"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1186"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_4_1_6"/>
    <dbReference type="OMA" id="GFSIHHE"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="109"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="512" mass="57099" checksum="949B7D2FD6B48D30" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI14</accession>
    <name>B1KI14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323838.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85492">
        <property type="protein sequence ID" value="ACA85492"/>
        <property type="gene ID" value="Swoo_1199"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1199"/>
    <dbReference type="HOGENOM" id="CLU_1863809_0_0_6"/>
    <dbReference type="OMA" id="SEEKMEY"/>
    <dbReference type="OrthoDB" id="2012206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15537" checksum="A7D49FE389F223EE" modified="2008-04-29" version="1">MEKSLLELLQRAALEFQGRELLILDIGIFPWHSSIELSLLFSDDQCARDDIAAWPHYDYSKFSEGGWCSAQPVAKQLACEWEKTSDIVGILKREAQVVNLPCIQEVLSSFKLAAEFRVQVLNSDDSHSPNYLYLGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI23</accession>
    <name>B1KI23_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323847.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1208"/>
    <dbReference type="MEROPS" id="S09.021"/>
    <dbReference type="EnsemblBacteria" id="ACA85501">
        <property type="protein sequence ID" value="ACA85501"/>
        <property type="gene ID" value="Swoo_1208"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1208"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017120_0_0_6"/>
    <dbReference type="OMA" id="FPIQSER"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764511" evidence="2">
        <location>
            <begin position="27"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="668"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="826"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="849" mass="95429" checksum="951B4FD1FA8D3F33" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI25</accession>
    <name>ANMK_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anhydro-N-acetylmuramic acid kinase</fullName>
            <ecNumber evidence="1">2.7.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">AnhMurNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">anmK</name>
        <name type="ordered locus">Swoo_1210</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:24952"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58690"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.170"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anhydro-N-acetylmuramic acid kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.170" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323849.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI25"/>
    <dbReference type="SMR" id="B1KI25"/>
    <dbReference type="STRING" id="392500.Swoo_1210"/>
    <dbReference type="EnsemblBacteria" id="ACA85503">
        <property type="protein sequence ID" value="ACA85503"/>
        <property type="gene ID" value="Swoo_1210"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1210"/>
    <dbReference type="eggNOG" id="COG2377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038782_0_0_6"/>
    <dbReference type="OMA" id="GQTIRHE"/>
    <dbReference type="OrthoDB" id="736294at2"/>
    <dbReference type="UniPathway" id="UPA00343"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097175">
        <property type="term" value="P:1,6-anhydro-N-acetyl-beta-muramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006040">
        <property type="term" value="P:amino sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01270">
        <property type="entry name" value="AnhMurNAc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="PTHR30605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000140176" description="Anhydro-N-acetylmuramic acid kinase">
        <location>
            <begin position="1"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01270"/>
        </source>
    </evidence>
    <sequence length="369" mass="39588" checksum="03E38437D662CFB6" modified="2008-04-29" version="1">MSKDYFIGLMSGTSMDGVDAVLVQFSQGEATLVERHSQAIPKHTLSGLQRLCLPGSDEITRLGQLDRSVGLLFASAVNALLEKAGVSKEQVVAIGSHGQTVRHMPNLDMGFTLQIGDPNTIAVETGIDVIADFRRKDIALGGQGAPLVPAFHQQMFSKPDTNRIILNIGGISNVTYLPGNSQAVVGFDTGPGNTLIDAWIQQVKHEAYDKDGAWAASGETDEKLLMYLLSHSYFSMGFPKSTGRELFNQAWLEQQTAAFGHLSEADIQSTLLDVTCHSIAKDVLTLSADGELFVCGGGAFNRELMSRLHNLLPSYQIDSTASLGMNPQWVEGIAFAWLAMRHNQGLSGNLPAVTGASREAVLGSLFPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI35</accession>
    <name>B1KI35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamate synthase, small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323859.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1220"/>
    <dbReference type="EnsemblBacteria" id="ACA85513">
        <property type="protein sequence ID" value="ACA85513"/>
        <property type="gene ID" value="Swoo_1220"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1220"/>
    <dbReference type="eggNOG" id="COG0493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_3_1_6"/>
    <dbReference type="OMA" id="DCVGTAH"/>
    <dbReference type="OrthoDB" id="671513at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006006">
        <property type="entry name" value="GltD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42783:SF1">
        <property type="entry name" value="PTHR42783:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01318">
        <property type="entry name" value="gltD_gamma_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer4_20" evidence="2">
        <location>
            <begin position="24"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="147"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="469" mass="50996" checksum="1A475A43964525AA" modified="2008-04-29" version="1">MSNDFQFIEVDRKDPVKHPAKKRATQFIEIYQPFAQTQVNEQADRCLDCGNPYCEWKCPLHNYIPNWLKLAQQGRILEAADLVHETNTLPEICGRVCPQDRLCEGACTLNDEFGAVTIGNVEKYITDTAIAQGWRPDLTKVTPRKERVAIIGAGPAGLGCADILARNGVQSVVFDKNPQIGGLLTYGIPAFKLDKSVMATRREVLEGMGIEFKLGVTVGADIPFEELVEQYDAVFLGMGTYTAMKAGLPGEDAQGVHQALPYLIGNTHNIMGTTDPDSPYLSLKGKKVVVLGGGDTAMDCVRTAVRQGATEVTCAYRRDEENMPGSRREVQNAKEEGVNFLFNRQPVAIETQDGIVTGITCVETQMGAADSSGRRRAEAIEGSEALLDADAIIIAFGFQPSPASWLKEHNVDLDEWGRVIAPKAADNPFQTTNPKIFAGGDMVRGSDLVVTAIAEGRDAALGILNTFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI38</accession>
    <name>B1KI38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hpt protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1223</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323862.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1223"/>
    <dbReference type="EnsemblBacteria" id="ACA85516">
        <property type="protein sequence ID" value="ACA85516"/>
        <property type="gene ID" value="Swoo_1223"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1223"/>
    <dbReference type="eggNOG" id="COG2198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2048146_0_0_6"/>
    <dbReference type="OMA" id="CAEAHKF"/>
    <dbReference type="OrthoDB" id="1632271at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="3">
        <location>
            <begin position="23"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="121" mass="13148" checksum="DF97C838104376EF" modified="2008-04-29" version="1">MATAEIESILDLNTLEQYCSAIGAGTLLKSVVLFEQLMPEYVGNLVNAKEAQDKDTLCSEAHKFKGAAGSVGLKRIQQFAQLLQHGEDAEWAAGHEAWLQAIVDNASLDLAELKQYLEAKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIF6</accession>
    <name>TOLB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tol-Pal system protein TolB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tolB</name>
        <name type="ordered locus">Swoo_2731</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TolB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325344.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIF6"/>
    <dbReference type="SMR" id="B1KIF6"/>
    <dbReference type="STRING" id="392500.Swoo_2731"/>
    <dbReference type="EnsemblBacteria" id="ACA87007">
        <property type="protein sequence ID" value="ACA87007"/>
        <property type="gene ID" value="Swoo_2731"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2731"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047123_0_0_6"/>
    <dbReference type="OMA" id="VREPSWG"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00671">
        <property type="entry name" value="TolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014167">
        <property type="entry name" value="Tol-Pal_TolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007195">
        <property type="entry name" value="TolB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04052">
        <property type="entry name" value="TolB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02800">
        <property type="entry name" value="propeller_TolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0574">Periplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5000316781" description="Tol-Pal system protein TolB" evidence="1">
        <location>
            <begin position="22"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00671"/>
        </source>
    </evidence>
    <sequence length="442" mass="48566" checksum="8BFC0231BE1F8E6F" modified="2008-04-29" version="1" precursor="true">MKTLGKWLLLGLVVMSMPARAALDIVITEGVDAARPIAVIPFVWQGQGPAPQQISDVVMSDLARSGTFNPIDELGLPQRNIAKVSQFVAKEWSNVAAEAVVMGSVKPMGPDQFLVNFELVDLVKAQMQAGNGPQSSSEYLIDSSEVVISAEQFRQYGHRISDIVYEKLTGIRGAFLTRIAYVVVKHGEKSPYHLMISDYDGHNEKMLLRSPEPLMSPSWSPDGSKLAYVSFENKKAEVFVQNIYTQARAKITSYDGINGAPVFSPDGKKLALTLSRDGQPEIYVVDIDTKALKRVTNHYAIDTEASWFPDGKSLIFTSERGGRPQIYKVTLASGKVQRMTFEGEWNLGGSISPDGRSMIFVNRTNGKFNIARMDLETRFVQVLTSTRLDESPSVAPNGTMVIYGTTYQGKQVLAAVSTDGRFKARLPAGQGEVKSPSWSPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIJ3</accession>
    <name>B1KIJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4233</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326816.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4233"/>
    <dbReference type="EnsemblBacteria" id="ACA88489">
        <property type="protein sequence ID" value="ACA88489"/>
        <property type="gene ID" value="Swoo_4233"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4233"/>
    <dbReference type="eggNOG" id="COG1127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="PKYLFCD"/>
    <dbReference type="OrthoDB" id="1058434at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="271" mass="29865" checksum="CE54C68CE38CD642" modified="2008-04-29" version="1">MDHQVLAEPKPLVEIHNLGFSRGEHVIFDDISLSIPRGKVTAIMGPSGIGKTTLLKLMGGQLTPDIGHVLFDGVDVHKCRREELFTLRKRMSMLFQSGALFTDMNVFDNVAFALREHSGLPEEIIKRIVLMKLEAVGLRGTANMMPNELSGGMQRRAALARAIALEPEMVMYDEPFAGQDPISMGVLVKLIRELSEALQLTSVVISHDVQEVLSIADYVYVMADKRVIAQGTPAELKASDMAQLKQFIGGEPDGPVPFHFPAEDYQKELIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK7</accession>
    <name>B1KIK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molybdenum ABC transporter, periplasmic molybdate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4247</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein ModA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326830.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4247"/>
    <dbReference type="EnsemblBacteria" id="ACA88503">
        <property type="protein sequence ID" value="ACA88503"/>
        <property type="gene ID" value="Swoo_4247"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4247"/>
    <dbReference type="eggNOG" id="COG0725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083611_0_0_6"/>
    <dbReference type="OMA" id="SGDYTWQ"/>
    <dbReference type="OrthoDB" id="1506401at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005950">
        <property type="entry name" value="ModA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01256">
        <property type="entry name" value="modA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766658" evidence="3">
        <location>
            <begin position="19"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="28364" checksum="89E1B2F370B7DA13" modified="2008-04-29" version="1" precursor="true">MKKWIAVAVLTLPFMANSTPLELRAAGSLKAAMAEIVSEYQQLESETVNAEFAPSGLLRKRIEEGERVDLFASANMKHPQTLHASDKSGSVVMFARNKLCAIAQPEVDVASDSLLEKMLQDSIKVGISTPKADPAGDYAWALFGRADKVQLGATQKLEHKAIKLTGGANTAVAPKGRNPYGWVMENRRADIFLTYCTNAVLAQKELPTLQIVQIPQALSVGANYGLTILEGANVNSTEFAMFILSQPGQNILAKYGFDAPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY7</accession>
    <name>B1KIY7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane pair domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323981.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1343"/>
    <dbReference type="EnsemblBacteria" id="ACA85635">
        <property type="protein sequence ID" value="ACA85635"/>
        <property type="gene ID" value="Swoo_1343"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1343"/>
    <dbReference type="eggNOG" id="COG4125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120004_1_0_6"/>
    <dbReference type="OMA" id="CFNLAYD"/>
    <dbReference type="OrthoDB" id="1784156at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007896">
        <property type="entry name" value="BTP_bacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05232">
        <property type="entry name" value="BTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="BTP" evidence="2">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="BTP" evidence="2">
        <location>
            <begin position="69"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15328" checksum="6E3D7E53EE97A311" modified="2008-04-29" version="1" precursor="true">MQTKERVFHAIMFELLALAIVVPLAAMFSSKGASSLMIVGVGLSLYAVIWNYFYNIWFDRKFGCDRASRTVTVRVAHTLGFEGGIIFITVPIVAWFLNISLGAALLMEAGFLIFFFFYAIGFNWCYDNIRSRMVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ18</accession>
    <name>B1KJ18_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325374.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2762"/>
    <dbReference type="EnsemblBacteria" id="ACA87038">
        <property type="protein sequence ID" value="ACA87038"/>
        <property type="gene ID" value="Swoo_2762"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2762"/>
    <dbReference type="eggNOG" id="ENOG502Z7NN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026769_0_1_6"/>
    <dbReference type="OMA" id="LKGWPIH"/>
    <dbReference type="OrthoDB" id="1250894at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011435">
        <property type="entry name" value="UmpAB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07556">
        <property type="entry name" value="DUF1538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="25787" checksum="18775D82037B4676" modified="2008-04-29" version="1">MAAIFKLLQSLLSSFKDLVPIILVVSFFEIFILQQAPTDLFSIMIGLVFIVFGLTFFVFGLEMGLFPIGESLAQALARKGSVFWLVLFSFSLGFGTTLAEPALTAVANEAAQVAAEAGAINEDKASMDSYAMGLRLTVAISVGLAILLGVVRILKGWPIHYLIIGGYVTVMVLTGFAPESIIGVAYDSGGVTTSTITVPLVTALGVGLASVIKGRNPMLDGFGLIAFASLTPMIFVLIYGMVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ40</accession>
    <name>B1KJ40_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_2784</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325396.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2784"/>
    <dbReference type="EnsemblBacteria" id="ACA87060">
        <property type="protein sequence ID" value="ACA87060"/>
        <property type="gene ID" value="Swoo_2784"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2784"/>
    <dbReference type="eggNOG" id="COG0720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962682_0_0_6"/>
    <dbReference type="OMA" id="HYTHGLK"/>
    <dbReference type="OrthoDB" id="993025at2"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="293" mass="33200" checksum="C191B75C06215FF2" modified="2008-04-29" version="1">MQLFVRDLTVIDFSYLCPIRGMVGESWIVDVLLDGGLDEQNMVLDFSKVKRTIKDTIDNVADHRLLIPTACSEVRWQQQGDRVWMDFNSLKGDIHLACPEQAFALIPSELIDFESVNTFLQKALKEVLPDNVDGIALTLRNELHETPFYHYSHGLKKHDGNCQRIAHGHRSPINIFENGISAPKWDEYWAERWKDIYLGTVEDVVKIDELTLSPQAKVSDDTHFGFHYQAPQGDFQLAMPKPMCEIIPHDTTVELLAEFVANTLVEKSPHSQFKVIAYEGVGKGAISVKGHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA8</accession>
    <name>B1KJA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4327"/>
    <dbReference type="EnsemblBacteria" id="ACA88580">
        <property type="protein sequence ID" value="ACA88580"/>
        <property type="gene ID" value="Swoo_4327"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4327"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_0_6"/>
    <dbReference type="OMA" id="QYVAHVE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045002">
        <property type="entry name" value="Ech1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149">
        <property type="entry name" value="PTHR43149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="32659" checksum="6B8985E94CD8CE73" modified="2008-04-29" version="1">MLSLLVKYAKYVNLASGLTSVNRESVMSREFVKIVREQGVAYVTLTRPDKYNAINYQMFKEIDGVISELKKDRTVKLVILSGAEGNFSSGLDVKSVMNSPLQAVGLLFKWLPGNANLAQRVSCGWRALPIPVIAVIEGCCFGGGMQIALGADIRLVSPEAKLSIMEAKWGLVPDMAGLISLRELVGKDRAMLLTMTAKVLSAQESLEVGLVTEVAQSPMARAKELAEEIICTSPDANAAIKMSINKSWTASVRRLLSRESISQIRLLMGKNRVIAAKRNSQDAKGVEPKSEYLIRQSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD6</accession>
    <name>B1KJD6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88608">
        <property type="protein sequence ID" value="ACA88608"/>
        <property type="gene ID" value="Swoo_4355"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4355"/>
    <dbReference type="HOGENOM" id="CLU_210444_0_0_6"/>
    <dbReference type="OMA" id="AMGGDFY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="57" mass="6637" checksum="AD60028B8F32747A" modified="2008-04-29" version="1">MAQMIDLVPDDLEIEAIAQPSNRKEMDDLMRRRNVKKRLEDVLAEAELQRAMGGDFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJH4</accession>
    <name>B1KJH4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326972.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4394"/>
    <dbReference type="EnsemblBacteria" id="ACA88646">
        <property type="protein sequence ID" value="ACA88646"/>
        <property type="gene ID" value="Swoo_4394"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4394"/>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012817_9_1_6"/>
    <dbReference type="OMA" id="IIYPLYM"/>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766711" evidence="3">
        <location>
            <begin position="21"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="362"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="465" mass="51370" checksum="5A13B2EAFCC3BADF" modified="2008-04-29" version="1" precursor="true">MKLTRLACLSLCLICGTTLAQPMTFNAAWQQLLTVSDKLQAESQEVIRAQAEQQAGEDLGMPSLDISGSYTHLEKPIELDLRDLNPLASLDPSSLPPALGGALASIPSSLFVTPFTEQDIFRASLQAMWPIYTGGKITAAQGIHEAQVAEKEQQLQLVTRDLFNLLVDRYYAVSVTEMLMQTQGQLVASLTEHVDHALKLEEQGQIAKVERLNAQVALENARVSAGSAKRQHEMAVIALSRMLHQQSVTTASELFMLSSQPSLPRLSQLTMTQHPALRLLEAKEEQASGLIEVEKGRYKPTVFLYGNYTLYEDDSLFSKVEPDWMVGLGVKVPLLSRDGRSGKVEAAKSALLQARYTKAQTQQDLSLLLDQSYRQLQQAQEEVVALNTSLSLAEENLRLREIAFNQGLSTSIDRVDAELKLSAVKTQQLGAKYRYVQSYARLMAISGQLDDFIGRTNGLNNFGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJH7</accession>
    <name>B1KJH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4397</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326975.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4397"/>
    <dbReference type="EnsemblBacteria" id="ACA88649">
        <property type="protein sequence ID" value="ACA88649"/>
        <property type="gene ID" value="Swoo_4397"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4397"/>
    <dbReference type="eggNOG" id="COG3164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003522_0_0_6"/>
    <dbReference type="OMA" id="SLPQSDW"/>
    <dbReference type="OrthoDB" id="29456at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011836">
        <property type="entry name" value="CHP02099"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025263">
        <property type="entry name" value="DUF3971"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38690">
        <property type="entry name" value="PTHR38690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13116">
        <property type="entry name" value="DUF3971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02099">
        <property type="entry name" value="TIGR02099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3971" evidence="3">
        <location>
            <begin position="510"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA_2" evidence="4">
        <location>
            <begin position="1029"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1273"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1273"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1293"/>
            <end position="1324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1392" mass="154554" checksum="55E672D9607C7FD6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJJ7</accession>
    <name>B1KJJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324016.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85670">
        <property type="protein sequence ID" value="ACA85670"/>
        <property type="gene ID" value="Swoo_1378"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1378"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="NERINQP"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="37558" checksum="2110D4F1DF14F30D" modified="2008-04-29" version="1">MPRPRRTQISIEDTPWYHCCSRVTRRAMLLGDDKFTGKNYDHRRDWVESQLLKLAGVFAIDVAAYAVMSNHLHVVLYVDLETVNRWSDRTVVEQWHKLFSGTEITQKFAKGEVIEEYQVAKLKHLIATYRSRLCDISWFMRCLNEPIARKANIEDNCTGHFWEGRFKSQALLDEAAVLACMAYVELNPIRAKMVDTLENSDHTSIQLRVNAALKGEQPTKLLPFIGDEQLNQPKGINFALKDYLELVDETGRIIRDDKRGSISANSTKILTRLNISSDNWIKLTSEFGKLFHGPVGETQSLTRYCEHLQKRRRHFSKSCLHFQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJS1</accession>
    <name>B1KJS1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324090.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1455"/>
    <dbReference type="EnsemblBacteria" id="ACA85744">
        <property type="protein sequence ID" value="ACA85744"/>
        <property type="gene ID" value="Swoo_1455"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1455"/>
    <dbReference type="eggNOG" id="ENOG5031H4R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_202424_0_0_6"/>
    <dbReference type="OMA" id="ECNEIDP"/>
    <dbReference type="OrthoDB" id="2093030at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019630">
        <property type="entry name" value="DUF2496_YbaM-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10689">
        <property type="entry name" value="DUF2496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="55" mass="5839" checksum="2FADBD7972CF811F" modified="2008-04-29" version="1">MATDTPKSSIDSASDEVKLAVDLIYLLESHNIDPQVALSAIEIVASDLKAKLVKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT6</accession>
    <name>ZIPA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division protein ZipA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">zipA</name>
        <name type="ordered locus">Swoo_2848</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with FtsZ via their C-terminal domains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Localizes to the Z ring in an FtsZ-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZipA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325459.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJT6"/>
    <dbReference type="SMR" id="B1KJT6"/>
    <dbReference type="STRING" id="392500.Swoo_2848"/>
    <dbReference type="EnsemblBacteria" id="ACA87123">
        <property type="protein sequence ID" value="ACA87123"/>
        <property type="gene ID" value="Swoo_2848"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2848"/>
    <dbReference type="eggNOG" id="COG3115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030174_1_0_6"/>
    <dbReference type="OMA" id="FWSIRKQ"/>
    <dbReference type="OrthoDB" id="1632200at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00509">
        <property type="entry name" value="ZipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011919">
        <property type="entry name" value="Cell_div_ZipA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007449">
        <property type="entry name" value="ZipA_FtsZ-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036765">
        <property type="entry name" value="ZipA_FtsZ-bd_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38685">
        <property type="entry name" value="PTHR38685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04354">
        <property type="entry name" value="ZipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00771">
        <property type="entry name" value="ZipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64383">
        <property type="entry name" value="SSF64383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02205">
        <property type="entry name" value="septum_zipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000127232" description="Cell division protein ZipA">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="6"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="28"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="311" mass="34516" checksum="850F9E9AB43977A3" modified="2008-04-29" version="1">MENLQLVLFVLGAIAIIAVLVHGFWSIRKQQPKSLKESPMSGFYKDQASVRDSQGFDADGIGEVRVRKEVPATDRQEKEDKPVQEPAFTAAPSRDVEDSRHEQAFALSDEPVQRAARQRQEPVLSMGANAKDDEVQMELGLGQDSQSSLFETVEQESVVEPTPEPEVKAEEPLGEPKDVLVLHVVANEGEELNGAELLPCLLSLNFKFGDMDIFHRHEDNAGTGKVLFSLANMVKPGVFNLDNMEQFTTEGVVLFMTLPCHGDPLMNFSIMLNSAHQLADDVGGRLLDGGREDWSESTKQLYLQRIRAQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT8</accession>
    <name>B1KJT8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sulfate transporter CysZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cysZ</name>
        <name evidence="9" type="ordered locus">Swoo_2850</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CysZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325461.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2850"/>
    <dbReference type="EnsemblBacteria" id="ACA87125">
        <property type="protein sequence ID" value="ACA87125"/>
        <property type="gene ID" value="Swoo_2850"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2850"/>
    <dbReference type="eggNOG" id="COG2981">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070331_1_0_6"/>
    <dbReference type="OMA" id="PFADDWS"/>
    <dbReference type="OrthoDB" id="1972181at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015116">
        <property type="term" value="F:sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00468">
        <property type="entry name" value="CysZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022985">
        <property type="entry name" value="Sulfate_CysZ"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="257" mass="29531" checksum="89FC72AB269D6040" modified="2008-04-29" version="1">MNQTAERPKKSGVNYFLDGFSLIKTKGLRSFVFIPLMINLVLFASVIYFAIGQLEQMFNWISSQLPDYLSWLNFLLWPLAVLTLLVVLSFLFSSVMNWLAAPFNGLLAEKVEQHLTGKDLNTGTTVDLVKDLPRILGREWKKLKYYLPRAIICLILFWIPFIGQTFAPIIWFMFSAWMMAIQYCDYPFDNHKVPFDDMKFALNQTKGSSFSFGAAVTLFSMIPIVNFIVMPVAICGATSMWVDKYREAYKHPEIAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK05</accession>
    <name>B1KK05_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arachidonate 15-lipoxygenase</fullName>
            <ecNumber evidence="5">1.13.11.33</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2919</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.13.11.33" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325528.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2919"/>
    <dbReference type="EnsemblBacteria" id="ACA87192">
        <property type="protein sequence ID" value="ACA87192"/>
        <property type="gene ID" value="Swoo_2919"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2919"/>
    <dbReference type="eggNOG" id="ENOG502Z9KW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004282_3_2_6"/>
    <dbReference type="OMA" id="CMDHWKE"/>
    <dbReference type="OrthoDB" id="247934at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050473">
        <property type="term" value="F:arachidonate 15-lipoxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="PTHR11771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00087">
        <property type="entry name" value="LIPOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="SSF48484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoxygenase" evidence="4">
        <location>
            <begin position="233"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="725" mass="82757" checksum="49FA2205C2281E7B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK50</accession>
    <name>HSLV_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent protease subunit HslV</fullName>
            <ecNumber evidence="1">3.4.25.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hslV</name>
        <name type="ordered locus">Swoo_4429</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent cleavage of peptide bonds with broad specificity.</text>
            <dbReference type="EC" id="3.4.25.2"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Allosterically activated by HslU binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327007.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KK50"/>
    <dbReference type="SMR" id="B1KK50"/>
    <dbReference type="STRING" id="392500.Swoo_4429"/>
    <dbReference type="MEROPS" id="T01.006"/>
    <dbReference type="EnsemblBacteria" id="ACA88681">
        <property type="protein sequence ID" value="ACA88681"/>
        <property type="gene ID" value="Swoo_4429"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4429"/>
    <dbReference type="eggNOG" id="COG5405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093872_1_0_6"/>
    <dbReference type="OMA" id="IMKGNAR"/>
    <dbReference type="OrthoDB" id="1129370at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01913">
        <property type="entry name" value="protease_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00248">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="PTHR32194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039093">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0021">Allosteric enzyme</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0915">Sodium</keyword>
    <keyword id="KW-0888">Threonine protease</keyword>
    <feature type="chain" id="PRO_1000100916" description="ATP-dependent protease subunit HslV">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00248"/>
        </source>
    </evidence>
    <sequence length="174" mass="18848" checksum="5387330A5C22BCCD" modified="2008-04-29" version="1">MTTIVSVRRNNQVVIAGDGQVSLGNTVMKGNAKKVRRLYHNKVLAGFAGGTADAFTLFERFEAKLEMHQGHLMKAAVEMAKDWRSDKMLRKLEALLAVADDTCSLIITGNGDVVQPENDLIAIGSGGNFAQSAATALLENTELTALEIAEKSLTIAGDICVFTNQFKTIEELNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK91</accession>
    <name>B1KK91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NosL family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327048.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4471"/>
    <dbReference type="EnsemblBacteria" id="ACA88722">
        <property type="protein sequence ID" value="ACA88722"/>
        <property type="gene ID" value="Swoo_4471"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4471"/>
    <dbReference type="eggNOG" id="COG4314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096026_0_0_6"/>
    <dbReference type="OMA" id="ASAFYVY"/>
    <dbReference type="OrthoDB" id="1678497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008719">
        <property type="entry name" value="N2O_reductase_NosL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41247">
        <property type="entry name" value="PTHR41247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05573">
        <property type="entry name" value="NosL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764596" evidence="1">
        <location>
            <begin position="22"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="17819" checksum="9C95E5BFEC9BE922" modified="2008-04-29" version="1" precursor="true">MKKLFCLLFLLPLLAACSDSAIDAKPLSAEAIHEHDRCHLCGMMITKYPGPKGQVHLKGQSIVPKFCSTRDMFNFALQAENKRQIEALFVHDLAVTDWAAPTDNAFIDATQAWYVYGTSKKAVMGPAVASFKRQDDAVKFATEFGGAVFSYEQIDIALLAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKB6</accession>
    <name>B1KKB6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324102.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1468"/>
    <dbReference type="EnsemblBacteria" id="ACA85756">
        <property type="protein sequence ID" value="ACA85756"/>
        <property type="gene ID" value="Swoo_1468"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1468"/>
    <dbReference type="HOGENOM" id="CLU_169696_0_0_6"/>
    <dbReference type="OrthoDB" id="2157170at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12676" checksum="35515852D04CCA8C" modified="2008-04-29" version="1" precursor="true">MNRVSFVFLLLISFTPFDVMSEGSGWSGKSKIEQLYAVNSSQVIVKLSNFTNATGCNPNTAGHVLVDTNSQKTFYTLILSAFMAGKEVNFYLYGECKTTHWVGPSFAGFGHVIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD4</accession>
    <name>B1KKD4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324120.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1486"/>
    <dbReference type="EnsemblBacteria" id="ACA85774">
        <property type="protein sequence ID" value="ACA85774"/>
        <property type="gene ID" value="Swoo_1486"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1486"/>
    <dbReference type="HOGENOM" id="CLU_2234744_0_0_6"/>
    <dbReference type="OrthoDB" id="1984107at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767151" evidence="1">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="11788" checksum="07993232493F0C4B" modified="2008-04-29" version="1" precursor="true">MRSFSLLVAFSCLIFANSIDAKRYWPSTTLTDWSLYLNNGVAYISSPQFPEHCLHSRGQINMSGTEFDKAQYAYALSAKARGKSLRYVIDNTHTTCVITGLLEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF6</accession>
    <name>B1KKF6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324142.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1508"/>
    <dbReference type="EnsemblBacteria" id="ACA85796">
        <property type="protein sequence ID" value="ACA85796"/>
        <property type="gene ID" value="Swoo_1508"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1508"/>
    <dbReference type="eggNOG" id="ENOG5032S51">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1395464_0_0_6"/>
    <dbReference type="OMA" id="QLIAVIW"/>
    <dbReference type="OrthoDB" id="2034026at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="184" mass="19706" checksum="468F841F2A507F7D" modified="2008-04-29" version="1">MTTFNDLIKALISCIETGKTCLLVLLFASITACGGGGGDESSAPAATTGTVTPPSTTPPTTTPTPDPDPDPAPEPTSLDDLVVAADNAMQAVFQLMISIDINSSKRAYFSLCDDYSGSNMSYEVNFESCRYRGSLIDGQLDADIKVANHNGQMLAVLWFYDGSAPSYQLWQYDAELEQQQLTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKK2</accession>
    <name>B1KKK2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325555.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2946"/>
    <dbReference type="EnsemblBacteria" id="ACA87219">
        <property type="protein sequence ID" value="ACA87219"/>
        <property type="gene ID" value="Swoo_2946"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2946"/>
    <dbReference type="eggNOG" id="COG3794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084768_2_0_6"/>
    <dbReference type="OMA" id="EIGCNIH"/>
    <dbReference type="OrthoDB" id="1869568at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767159" evidence="1">
        <location>
            <begin position="27"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="223" mass="25305" checksum="1189A3A926805035" modified="2008-04-29" version="1" precursor="true">MSYRWARVLCSGLFLVPLGWSFAANAEKVRLVDSSGEPMPDLVVYLEAKNSQQHTVGNKVTPPLEIHQKDKQFTPYITVMQKGYELQFVNDDDITHHIYSAAGPKRFSFKLRKDNSTKTLRFEQEGHISMGCNIHDWMSGHLLVVDTPYFAIADESGEVEFDGVPNAEYELMVWHPQLQVENNTLMQTVTTSSSTPIIVTIDVPMADIPEQKSLDDFDFLEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL4</accession>
    <name>B1KKL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325567.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87231">
        <property type="protein sequence ID" value="ACA87231"/>
        <property type="gene ID" value="Swoo_2958"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2958"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="HEGSACE"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="37678" checksum="DA42FE1E56D30B82" modified="2008-04-29" version="1">MPRPRRTQISLEDTPWYHCCSRVTRRAMLLGDDKFTGKNYDHRRDWVESQLLKLAGVFAIDVAAYAVMSNHLHVVLYIDIETVNRWSDRTVVEQWHKLFNGTEITQKFAKGEVIEEQQVAKLKHLIATYRSRLCDISWFMRCLNEPIARKANIEDNCTGHFWEGRFKSQALLDEAAVLACMAYVELNPIRAKIVDTLENSDHTSIQLRVNAALKGEQPTQLLPFIGDERLNQPKGINFTLKDYLELVDETGRVIRDDKRGSISKNCTKILTRLNISSDNWIKLTSEFGKLFHGPVGETQSLTRYCEHLQKRRRHFSKSCQHFQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL16</accession>
    <name>B1KL16_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1732 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4572"/>
    <dbReference type="EnsemblBacteria" id="ACA88822">
        <property type="protein sequence ID" value="ACA88822"/>
        <property type="gene ID" value="Swoo_4572"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4572"/>
    <dbReference type="eggNOG" id="COG1561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076609_2_1_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005229">
        <property type="entry name" value="CHP00255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013551">
        <property type="entry name" value="DUF1732"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30636">
        <property type="entry name" value="PTHR30636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08340">
        <property type="entry name" value="DUF1732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1732" evidence="1">
        <location>
            <begin position="49"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14704" checksum="67CBC849BF7E6B36" modified="2008-04-29" version="1">MLQTRLDAIVEQVAIVREHMPTVMQWQRDKLTNRLAEITGELDPARLEQEMVILAQKMDVAEEMDRLDAHVAETQRILKKGGAQGRRLDFMMQEFNRESNTLASKSISSDVTAAAVELKVLIEQIQNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE4</accession>
    <name>B1KLE4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LmbE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324215.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1583"/>
    <dbReference type="EnsemblBacteria" id="ACA85869">
        <property type="protein sequence ID" value="ACA85869"/>
        <property type="gene ID" value="Swoo_1583"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1583"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_6_0_6"/>
    <dbReference type="OMA" id="EAFMLVR"/>
    <dbReference type="OrthoDB" id="1282433at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="25218" checksum="D41BDCCAA6F2E789" modified="2008-04-29" version="1">MKTKKVLVIAPHADDESLGCGGTILKHIDIGDEVHWLIVTGMSLDSGFSEEQINIRKDEIAKVGLLYKFKQVHELFLPPASLDCLPKKNIISAISSVIQSVEPELIYTAYRNDAHSDHEVVFDAITASSKTFRYPSIKRILAYETLSETDFGLKPEDGGFKPNVFVDISDFLEQKLNILDHFESEMSHFPFPRSRKAISSLSFVRGVQAGCESAEAFMLLKEIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLF9</accession>
    <name>B1KLF9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Flagellar basal-body rod protein FlgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1598</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5 6">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1598"/>
    <dbReference type="EnsemblBacteria" id="ACA85884">
        <property type="protein sequence ID" value="ACA85884"/>
        <property type="gene ID" value="Swoo_1598"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1598"/>
    <dbReference type="eggNOG" id="COG1558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123272_1_0_6"/>
    <dbReference type="OMA" id="YVAYPNI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006299">
        <property type="entry name" value="FlgC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01395">
        <property type="entry name" value="FlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="8"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="8">
        <location>
            <begin position="92"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15182" checksum="2CA5C51473B34B73" modified="2008-04-29" version="1">MMSLFNIFNVSGSGMSAQSVRLNTTASNIANADSVSSSIDETYRARHPIFEAEMAKASHQQQSSQSVAVKGIVESDAPLQKEYSPNHPMADTDGFIYKPNVNVMEEMADMISASRSYQMNVQVAEAAKSMLQQTLRIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM77</accession>
    <name>B1KM77_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heavy metal efflux pump, CzcA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0189</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322839.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0189"/>
    <dbReference type="EnsemblBacteria" id="ACA84490">
        <property type="protein sequence ID" value="ACA84490"/>
        <property type="gene ID" value="Swoo_0189"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0189"/>
    <dbReference type="eggNOG" id="COG3696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="EAEYMIT"/>
    <dbReference type="OrthoDB" id="91817at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="875"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="899"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="924"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="983"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1013"/>
            <end position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1044" mass="114730" checksum="C48E053087CB8C86" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM94</accession>
    <name>B1KM94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">O-succinylbenzoate-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322856.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0206"/>
    <dbReference type="EnsemblBacteria" id="ACA84507">
        <property type="protein sequence ID" value="ACA84507"/>
        <property type="gene ID" value="Swoo_0206"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0206"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_6"/>
    <dbReference type="OMA" id="PIAYYPL"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008756">
        <property type="term" value="F:o-succinylbenzoate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010192">
        <property type="entry name" value="MenE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01923">
        <property type="entry name" value="menE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="16"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="504" mass="55086" checksum="2882AE1F0FF4C2B9" modified="2008-04-29" version="1">MATDKFQLRALSPLHQAAVDYPERDALVWHQDGVKHQLSYSALSQKVVAIGEQLTAQGLLPGDRLACIDVNSVELILLYWACIDTGVIFCPLSPRFPIKQLSKLIKQHRLNYIWSGAHYSPLFSSHQAKPQVPELLFSDNGLSTAKLTVDFNSSSRAKAVEVSIESPANLILTSGSSGQPKAAVHSLSNHIVSATGSADQIPLEVGDAWLLSLPLFHIGGLAIINRCALAGAAVVMQDKTLSLTAQLKQTPITHLSLVSTQLVHLLESQSTTKESSPLQGVKSLLLGGGAISLDLIERLNTLNINSFTSYGMTEMSSQITTGTASADGSCGQTITGRELKIVDEQIYVRGGTLFLGYLEWSDNQAKFNLPLEDGWFPTKDRGYWDKQGKLHILGRCDNMFVCGGENVQPEEIEAALKLHPQIDDAIVFPQTDSEFGHLPTAVIKPSLLCTEGIEQLTASDEFEQFLCDKIARFKRPRLYYPWPEVESVGLKVSRKLVIEAVLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC2</accession>
    <name>B1KMC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Dimethylsulfoxide reductase, chain B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0234</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322884.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0234"/>
    <dbReference type="EnsemblBacteria" id="ACA84535">
        <property type="protein sequence ID" value="ACA84535"/>
        <property type="gene ID" value="Swoo_0234"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0234"/>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_2_0_6"/>
    <dbReference type="OMA" id="CEMACKD"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014297">
        <property type="entry name" value="DMSO_DmsB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12800">
        <property type="entry name" value="Fer4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02951">
        <property type="entry name" value="DMSO_dmsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="7"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="75"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="24530" checksum="4E88B486591A4D0C" modified="2008-04-29" version="1">MTQPTQYGFYVDSTKCTGCKACHVSCKDRQSNEIRNNSNPEGNALPALEGVTWRRVYEYGGGEWTVGNNGCFEQNVFAYYMSIGCNHCSEPVCVKACPTGAMHKRRQDGLVHVAQDLCIGCESCARACPYDAPQIDSERKVMTKCDGCFERIAEGRKPVCVESCPLRALDFDTMDNLRAKYGDGDGHIAPLPSPSITSPNLIIKANVNGRPAGSGEGQILNFSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMT6</accession>
    <name>B1KMT6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325800.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="S09.074"/>
    <dbReference type="EnsemblBacteria" id="ACA87464">
        <property type="protein sequence ID" value="ACA87464"/>
        <property type="gene ID" value="Swoo_3193"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3193"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012236_1_0_6"/>
    <dbReference type="OMA" id="EVWCVLE"/>
    <dbReference type="OrthoDB" id="154149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767220" evidence="2">
        <location>
            <begin position="21"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="452"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="675" mass="74330" checksum="577A90F5C52F67BC" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMU0</accession>
    <name>B1KMU0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325804.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3198"/>
    <dbReference type="EnsemblBacteria" id="ACA87468">
        <property type="protein sequence ID" value="ACA87468"/>
        <property type="gene ID" value="Swoo_3198"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3198"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_22_1_6"/>
    <dbReference type="OMA" id="GKPYIAF"/>
    <dbReference type="OrthoDB" id="1238555at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="PTHR43176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ECH_2" evidence="2">
        <location>
            <begin position="28"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="381" mass="41914" checksum="AFAC1E605AC18DCD" modified="2008-04-29" version="1">MTTQTDKPIANNNSVVFQTLGTVSGKQIGVVTLNVEKAINSLNLEMVYAMTAQLKAWREDDDIALVMLDGAGDKGFCAGGDVRAIYHASMMTPGELTQDAVEFFENEYQLDYLLHSFPKPVMVWGDGIVMGGGLGLMAGASHRVLTERSRIAMPEVTIGLYPDVGGSYFLNRMPGDTGLFLGLTAYNMNAGDAKFVNIGNHYLNSDDKEPMLDHLATLSWSGDNDANHELLSQELNLLEQRVAISIPGSQLAEKQAEIAELMSGSLSEIIERVSHSDFSDTWLARPIKTLLSGSPISWHLIYRQALLGTDLSLTDVFKFELGLSVNCCAIGDFSEGVRALLIDKDRMPNWRYQSVADVPQDLIEKMTCSPWQTDNHPLKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN58</accession>
    <name>B1KN58_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0254</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322904.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0254"/>
    <dbReference type="EnsemblBacteria" id="ACA84555">
        <property type="protein sequence ID" value="ACA84555"/>
        <property type="gene ID" value="Swoo_0254"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0254"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_47_1_6"/>
    <dbReference type="OMA" id="PLYRWSR"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="5"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="400" mass="42898" checksum="4909EC46CA238954" modified="2008-04-29" version="1" precursor="true">MRRNLLPILMSMVVLSPLAIDIYLPSMPAMATEFAVSASDVQSTLILFLFAMGVGQIVIGPLADRFGRRPIALGGVLLYIASSILAAVAMEFHWLQIARVLQGLAACSTSIVVFSAVRDCFTPKEGARYYSYLNGVICVIPALAPTLGGLLALQFGWRSTFVFMTLYAIVMMILIGYRLPETRPANTVTTGPLYRWSRYQPVLVEPHFVFYALCCMAGMASILSYVSYAPVWLIDNLGVSELTFSGLFGLNAVVNIAACFAAPMVINRLGNRPTVILALVTMLASALIQVLLQGVGPTQGLAAAFSFMLPMMLLCIGFALLLGPATSMALAAFGERAGTATAILGFIQMSGASLIAGLVQQTELTAPYAVAVVMGALTSGLLIVMAMSRFDHWHQEQYAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN81</accession>
    <name>B1KN81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322927.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84578">
        <property type="protein sequence ID" value="ACA84578"/>
        <property type="gene ID" value="Swoo_0277"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0277"/>
    <dbReference type="eggNOG" id="ENOG5030K42">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055116_0_0_6"/>
    <dbReference type="OMA" id="SVWARSN"/>
    <dbReference type="OrthoDB" id="366918at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767517" evidence="1">
        <location>
            <begin position="19"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="414" mass="47124" checksum="A91AE032F9B44DFA" modified="2008-04-29" version="1" precursor="true">MKYMVLFSGLLFSNVLVASELPDFLDMNDIENAKFQCLGESPQYSAQDQKYIDILWEETLTYLRAYAEALTNDQNSGCLNSDIAMVDSTEGGQHMCVMDRRDMKLMVKNVYQVINNADAAKKCFGAREDVSWIYSPGGELESRSEVAQWINRTTFKQFFDKQVTDKEVQQYGKSFTENFYKMVTGSEIKMPAVFPHDISANALPNLWASAGWFPMYAEESERNDKNFNNIRGGYAYAEIFGHWGLLRIDEINGEKVGAEIGMTVQAVNSLYPFHNHAVSEMYYNMRTPACANQFRTMAIREDSPLIRTVKEDSKVRRVQFDEGQHNSQTMWLSGSNAQDSLTYFHQNTIHAFDIDGQCEASPEERAIVSVWARSNAHDTRNDYGTTLLCESAKHPGTPAKRGEVIQCDLTKVKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN88</accession>
    <name>B1KN88_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322934.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0284"/>
    <dbReference type="EnsemblBacteria" id="ACA84585">
        <property type="protein sequence ID" value="ACA84585"/>
        <property type="gene ID" value="Swoo_0284"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0284"/>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_13_1_6"/>
    <dbReference type="OMA" id="LWDNDGL"/>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="221" mass="24864" checksum="E56EB3CEE3311609" modified="2008-04-29" version="1">MASPLIKAVIFDMDGVLIDSEPAWQLAEYQTMRNQGLKISYQDTLQTTGLRIDEVVSYWYQRFPWKDYDNPKTATEIVNKVVQHILDDGTAMQGVFKALDFCEANGLKIGLATSSSQAIIQAVLNKLEIGHYFSSIQSAEHLNRGKPHPEVYLNCIDDLELSCSQCVAIEDSFNGLIAARAANMQTIAIPAPEQKNDQKWIIAHKQLDSLLELPEYLQDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNH0</accession>
    <name>B1KNH0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YaeQ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324393.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1763"/>
    <dbReference type="EnsemblBacteria" id="ACA86047">
        <property type="protein sequence ID" value="ACA86047"/>
        <property type="gene ID" value="Swoo_1763"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1763"/>
    <dbReference type="eggNOG" id="COG4681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096741_0_0_6"/>
    <dbReference type="OMA" id="WIELGQP"/>
    <dbReference type="OrthoDB" id="1464975at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009822">
        <property type="entry name" value="YaeQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038590">
        <property type="entry name" value="YaeQ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38784">
        <property type="entry name" value="PTHR38784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07152">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011484">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01322">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="20618" checksum="44BDD79ADBCCFD42" modified="2008-04-29" version="1">MAPKATVYKVNLQIADIDRGYYQDHNLTLAQHPSETDSRMMLRLLAFAMNASDTLEFSKGLCVEDEPELWEKTLVGDIELWIEFGQSDEKWLRKASGRAKQVQLFAYGGRSVPIWWQQNEQAFSRYKNLKVWNIPENAVKEMGELVSRSMSLQYNISEGQIWVSNDDGSVLVEPELLKE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNK1</accession>
    <name>Y1794_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein Swoo_1794</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1794</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324424.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNK1"/>
    <dbReference type="SMR" id="B1KNK1"/>
    <dbReference type="STRING" id="392500.Swoo_1794"/>
    <dbReference type="EnsemblBacteria" id="ACA86078">
        <property type="protein sequence ID" value="ACA86078"/>
        <property type="gene ID" value="Swoo_1794"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1794"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140930_0_0_6"/>
    <dbReference type="OMA" id="MGNMMKQ"/>
    <dbReference type="OrthoDB" id="1883809at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000114648" description="Nucleoid-associated protein Swoo_1794">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="109" mass="11873" checksum="F4860683BB53CAC2" modified="2008-04-29" version="1">MFGKGGMGNLMKQAQQMQDKMAKVQEEIARMEVTGEAGAGLVKVTMTGSHSVRKVDIDPSLLEDDKEMLEDLIAAACNDAARRVEENQKDKMAEVTGGMQLPPGMKMPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNN0</accession>
    <name>B1KNN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase U32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325824.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3218"/>
    <dbReference type="MEROPS" id="U32.003"/>
    <dbReference type="EnsemblBacteria" id="ACA87488">
        <property type="protein sequence ID" value="ACA87488"/>
        <property type="gene ID" value="Swoo_3218"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3218"/>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011540_4_0_6"/>
    <dbReference type="OMA" id="CEKPRID"/>
    <dbReference type="OrthoDB" id="1264653at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="757" mass="84834" checksum="36CE67C49A05D1EC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNT2</accession>
    <name>FABZ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="1">4.2.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase</fullName>
            <shortName evidence="1">(3R)-hydroxymyristoyl-ACP dehydrase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Beta-hydroxyacyl-ACP dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabZ</name>
        <name type="ordered locus">Swoo_3270</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioester dehydratase family. FabZ subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325876.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNT2"/>
    <dbReference type="SMR" id="B1KNT2"/>
    <dbReference type="STRING" id="392500.Swoo_3270"/>
    <dbReference type="EnsemblBacteria" id="ACA87540">
        <property type="protein sequence ID" value="ACA87540"/>
        <property type="gene ID" value="Swoo_3270"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3270"/>
    <dbReference type="eggNOG" id="COG0764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078912_1_0_6"/>
    <dbReference type="OMA" id="FPGRPLM"/>
    <dbReference type="OrthoDB" id="1763197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00406">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000123666" description="3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00406"/>
        </source>
    </evidence>
    <sequence length="152" mass="17284" checksum="B21459B7DC70D728" modified="2008-04-29" version="1">MSEQLNTMDIKEIMSFLPHRYPFLLIDRVLDYTPGETLHAIKNVTINEPFFQGHFPVQPVMPGVLILEAMAQATGLLAYKTMKEASEDSLYYFAGIDKARFKRVVEPGDQLHFEVKMIKERRGIGVFTGEVKVDGELVCSAEIMCARREISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNV2</accession>
    <name>B1KNV2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF446 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325896.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3290"/>
    <dbReference type="EnsemblBacteria" id="ACA87560">
        <property type="protein sequence ID" value="ACA87560"/>
        <property type="gene ID" value="Swoo_3290"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3290"/>
    <dbReference type="eggNOG" id="COG3098">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130358_0_0_6"/>
    <dbReference type="OMA" id="FIPRMYA"/>
    <dbReference type="OrthoDB" id="1989136at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007384">
        <property type="entry name" value="UCP006257"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023376">
        <property type="entry name" value="YqcC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036814">
        <property type="entry name" value="YqcC-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39586">
        <property type="entry name" value="PTHR39586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04287">
        <property type="entry name" value="DUF446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006257">
        <property type="entry name" value="UCP006257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158452">
        <property type="entry name" value="SSF158452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF446" evidence="1">
        <location>
            <begin position="7"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="12028" checksum="2CC87BB70090DA13" modified="2008-04-29" version="1">MLYANTTEKLHQLETELKVHGLWSSVPPSTEAMANTSPFSCDVMPFENWVQFIFIPKMEQLINSQNALPSNIAIAPMAHHVWNHQPDLHGLINIFDELDRMLSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX0</accession>
    <name>B1KNX0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325914.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3309"/>
    <dbReference type="EnsemblBacteria" id="ACA87578">
        <property type="protein sequence ID" value="ACA87578"/>
        <property type="gene ID" value="Swoo_3309"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3309"/>
    <dbReference type="eggNOG" id="ENOG5033AD4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144870_2_0_6"/>
    <dbReference type="OMA" id="AMFSHYR"/>
    <dbReference type="OrthoDB" id="2002203at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021762">
        <property type="entry name" value="DUF3325"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11804">
        <property type="entry name" value="DUF3325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12462" checksum="97A021682879590D" modified="2008-04-29" version="1" precursor="true">MISNSMTLSLLTFSYLALGCMALAMFSHFRDSFKRSPTPAQSRGLYWIGWGILALCYYLGIRYLGFAYGSILFTGILSFAGLLVILTASYQPKHLPHLMAGSSSLGVALMFMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ9</accession>
    <name>B1KNZ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pseudouridine synthase Rlu family protein, TIGR01621</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327347.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4781"/>
    <dbReference type="EnsemblBacteria" id="ACA89030">
        <property type="protein sequence ID" value="ACA89030"/>
        <property type="gene ID" value="Swoo_4781"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4781"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_6_0_6"/>
    <dbReference type="OMA" id="FHSQDGS"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006508">
        <property type="entry name" value="PsdUridine_synth_RluA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01621">
        <property type="entry name" value="RluA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="10"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="25285" checksum="00F3EE52BFE3DEA8" modified="2008-04-29" version="1">MYQIVADETDFIVIAKSHNVHFHSQDGSAGVMAKLEQDLGVKLFSVHRLDTLTSGLLLFAKSSQAAAEFTRLFTEHRVQKYYLALAKGKPKKKQGSIIGDMAKSRRSMYKLMRTMDNPAKTQFFSQSVAEGLRLYLLKPLSGKTHQLRVALASIGVPILGDTLYGGEESDRGYLHAFSLHFIFSGKEYQYINYPSEGVSFTALNTIKQLQMWSEPEKLDWPKQK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP42</accession>
    <name>RLMF_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase F</fullName>
            <ecNumber evidence="1">2.1.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA mA1618 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA adenine N-6-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmF</name>
        <name type="ordered locus">Swoo_4824</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the adenine in position 1618 of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(1618) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(1618) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16497"/>
            <dbReference type="Rhea" id="RHEA-COMP:10229"/>
            <dbReference type="Rhea" id="RHEA-COMP:10231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.181"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. METTL16/RlmF family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.181" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327390.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP42"/>
    <dbReference type="SMR" id="B1KP42"/>
    <dbReference type="STRING" id="392500.Swoo_4824"/>
    <dbReference type="EnsemblBacteria" id="ACA89073">
        <property type="protein sequence ID" value="ACA89073"/>
        <property type="gene ID" value="Swoo_4824"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4824"/>
    <dbReference type="eggNOG" id="COG3129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027534_3_0_6"/>
    <dbReference type="OMA" id="HQGRYDF"/>
    <dbReference type="OrthoDB" id="1027015at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052907">
        <property type="term" value="F:23S rRNA (adenine(1618)-N(6))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01848">
        <property type="entry name" value="23SrRNA_methyltr_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016909">
        <property type="entry name" value="rRNA_lsu_MeTfrase_F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="PTHR13393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029038">
        <property type="entry name" value="Mtase_YbiN_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000349966" description="Ribosomal RNA large subunit methyltransferase F">
        <location>
            <begin position="1"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="382" mass="42595" checksum="FBC35B57C6769C31" modified="2008-04-29" version="1">MTKPSSKASRKPVTKSGRNSKRSRSGSSKGDAQVARAINNQKPGLHPRNLHRDGYDFDKLTKVSPVLTPYVQPNPYGNLSIDFADPQAVKALNAAILKLDYQIDNWDIPEGFLCPPIPGRVDYLHYIYDLLAGVEEFENKSETEMEGQNVPPVNSHTIKPKKMKIKALDIGTGANAIYPLLGIQTYGWRFVASDVDPISLANVKAIVEGNNCLLGKLEVRLQNDHQKVFSGIIKPDDRFDITLCNPPFHASLKEASEGSQRKLKNLAENRASKGHKLEPKAPKDKSQLNFGGQKAELWCEGGEKQFLHNMICESKVFATQCLWFTSLVSKKENLEACYTELKRVGAITVKTIDMAQGNKLTRVLAWSFLTPSQRGLWAKYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP53</accession>
    <name>B1KP53_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327401.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4835"/>
    <dbReference type="EnsemblBacteria" id="ACA89084">
        <property type="protein sequence ID" value="ACA89084"/>
        <property type="gene ID" value="Swoo_4835"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4835"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1509593_0_0_6"/>
    <dbReference type="OMA" id="YIGYAQS"/>
    <dbReference type="OrthoDB" id="1649209at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767261" evidence="1">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="19935" checksum="1F83DFCB183484CC" modified="2008-04-29" version="1" precursor="true">MLRYLIMLSALTVSLNVMANQAEDDTSTLFKPKMSISLDYIPAENNMYGITLAPYHFDTDYSSWGYYIGYAASQKEDLALIKPAEGYTQDKMWRFGLSYSLTQQLSLYGGAVHYSLEKHFTTGKTPKIVDGEPIWEKESDTSWGGELGVRYMMDMGLMLGVGYNTSTDSAVISVGYVM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP56</accession>
    <name>HUTU_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Urocanate hydratase</fullName>
            <shortName evidence="1">Urocanase</shortName>
            <ecNumber evidence="1">4.2.1.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Imidazolonepropionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hutU</name>
        <name type="ordered locus">Swoo_4838</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-imidazolone-5-propanoate = H2O + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:13101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="4.2.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="1">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the urocanase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.49" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327404.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP56"/>
    <dbReference type="SMR" id="B1KP56"/>
    <dbReference type="STRING" id="392500.Swoo_4838"/>
    <dbReference type="EnsemblBacteria" id="ACA89087">
        <property type="protein sequence ID" value="ACA89087"/>
        <property type="gene ID" value="Swoo_4838"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4838"/>
    <dbReference type="eggNOG" id="COG2987">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018868_0_1_6"/>
    <dbReference type="OMA" id="MAKQHFN"/>
    <dbReference type="OrthoDB" id="100619at2"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016153">
        <property type="term" value="F:urocanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00577">
        <property type="entry name" value="HutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023637">
        <property type="entry name" value="Urocanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035401">
        <property type="entry name" value="Urocanase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038364">
        <property type="entry name" value="Urocanase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023636">
        <property type="entry name" value="Urocanase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035400">
        <property type="entry name" value="Urocanase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035085">
        <property type="entry name" value="Urocanase_Rossmann-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036190">
        <property type="entry name" value="Urocanase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12216">
        <property type="entry name" value="PTHR12216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01175">
        <property type="entry name" value="Urocanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17392">
        <property type="entry name" value="Urocanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17391">
        <property type="entry name" value="Urocanase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001423">
        <property type="entry name" value="Urocanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111326">
        <property type="entry name" value="SSF111326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01228">
        <property type="entry name" value="hutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01233">
        <property type="entry name" value="UROCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0369">Histidine metabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000129577" description="Urocanate hydratase">
        <location>
            <begin position="1"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="52"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="176"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="242"/>
            <end position="243"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="263"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="273"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00577"/>
        </source>
    </evidence>
    <sequence length="556" mass="60414" checksum="C1C864FCFD55F9FB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP74</accession>
    <name>B1KP74_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3 8">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0343</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322993.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0343"/>
    <dbReference type="REBASE" id="17469">
        <property type="entry name" value="M.SwoADam"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84644">
        <property type="protein sequence ID" value="ACA84644"/>
        <property type="gene ID" value="Swoo_0343"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0343"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063430_0_1_6"/>
    <dbReference type="OMA" id="MNRHGFN"/>
    <dbReference type="OrthoDB" id="1206955at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00571">
        <property type="entry name" value="dam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000398-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="31979" checksum="2D33983B2F31F1A2" modified="2008-04-29" version="1">MSKKQRAFLKWAGGKFKLIEALTEHLPEGQRLVEPFVGAGSVFLNTDYPSYLLCDINKDLINLYKIIQKEPEKYIAAAKAMFVPEMNEKEAYYRVRAEFNLSTDPFLRSVYFLYMNRHGFNGLCRYNRKGGFNVPFGSYKKPYFPENEIRAFSEKAQKAEFKCIGYEDAFELTTSGDVVYCDPPYAPLSTTASFTTYVGTGFSLDDQALLARKSRHTAIDNGIPVLISNHDIPLTRELYHGARFDTIQVQRNISQKGSARKKVDELMALYDDRYHSEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA0</accession>
    <name>B1KPA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84670">
        <property type="protein sequence ID" value="ACA84670"/>
        <property type="gene ID" value="Swoo_0371"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0371"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_11_3_6"/>
    <dbReference type="OMA" id="CALYCPE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="205" mass="22862" checksum="ED0DC75533E35868" modified="2008-04-29" version="1">MSIRVNTHFDFSHIQGVIFDLDGTLADSNPDFEGLRRELGLKSGTDILAHMESIIDPVLASKTKEIVTRYELESSSRATWVTGAEQLVALFRRLKLPQAILTRNIPQAAGITLANLGLEMDLVLTRFDAKAKPHPEGVELICEQWQLEPANILFIGDYLYDLQTARNAGTKSVLYSPDLIPDYASQADIVCQCYTALIQHFNTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPB3</accession>
    <name>B1KPB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323032.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0384"/>
    <dbReference type="EnsemblBacteria" id="ACA84683">
        <property type="protein sequence ID" value="ACA84683"/>
        <property type="gene ID" value="Swoo_0384"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0384"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_879131_0_0_6"/>
    <dbReference type="OMA" id="ISKELWT"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="133"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="313" mass="34581" checksum="2F88D6E13C540414" modified="2008-04-29" version="1">MSQSVRQSVMQASREWIANFNQGNVQACTERYQKEATMQVSPFGRFNGMEAIAGFWNEFAKSGPTKLVYRNVEIKVLNDKQAILSANWSMNIASGFISKELWTLNDDGQWYLEEDDFSVLTQHPAPLDDDKRTALVLVDLQNDYFSGGRFPLDNTDIATQHAKTLLSHFRKNALPVIHIQHIFEDDNAPFFTANTTGIEIETSVAPLAEEPVVIKHQIDSFIDTSLEQSLVELGVDKLVIVGAMAQACVQTITRSAVNKGYSCEVISDAIAAPSLPYGEHKFSGDQLVAANLLSLSFGGAKATTSTQWLKDNA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPJ7</accession>
    <name>BIOB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Biotin synthase</fullName>
            <ecNumber evidence="1">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bioB</name>
        <name type="ordered locus">Swoo_1866</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="1">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324496.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPJ7"/>
    <dbReference type="SMR" id="B1KPJ7"/>
    <dbReference type="STRING" id="392500.Swoo_1866"/>
    <dbReference type="EnsemblBacteria" id="ACA86150">
        <property type="protein sequence ID" value="ACA86150"/>
        <property type="gene ID" value="Swoo_1866"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1866"/>
    <dbReference type="eggNOG" id="COG0502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033172_1_2_6"/>
    <dbReference type="OMA" id="ADRFCMG"/>
    <dbReference type="OrthoDB" id="940969at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0001">2Fe-2S</keyword>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0093">Biotin biosynthesis</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000381630" description="Biotin synthase">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="41"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <sequence length="354" mass="39584" checksum="FEF8872CC43CB42C" modified="2008-04-29" version="1">MSEIQLRHDWKRDEIEALFALPMNDLLFEAHSIHRQVYDPNEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLIEIEKVLTEARSAKAAGASRFCMGAAWRNPHARDMPYLKDMVREVKSMGMETCMTLGMLSPDQAGELAEAGLDYYNHNLDTSPEYYGDIITTRTYQDRLDTLSNVRAAGMKVCSGGIVGMGEQATDRSGLLQQLANMEQHPDSVPINMLVKVAGTPFENLEDLDPLVFVRTIAVARILMPHSRVRLSAGREKMSDEMQAMCFFAGANSIFYGCKLLTTNNPEENEDMTLFKRLGLHPEQGKYATIEDDKAVFEKATAKANAIKDKQSSAFYDAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPK4</accession>
    <name>B1KPK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1873</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1873"/>
    <dbReference type="EnsemblBacteria" id="ACA86157">
        <property type="protein sequence ID" value="ACA86157"/>
        <property type="gene ID" value="Swoo_1873"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1873"/>
    <dbReference type="eggNOG" id="COG0547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043389_0_0_6"/>
    <dbReference type="OMA" id="KRELLPW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="3">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="41217" checksum="EB1D76BE44628440" modified="2008-04-29" version="1">MHGTIMTNTSMMKKSYQALVKALGRGTKGSRSLTLEESTFLITGFYDGYGTRSQLATSLMLMRVRGETTDEIAGVTLGIQSTISPEWKTIGASIDWPCYAGKRDMLPWLLLAAKVLAKEGERVLLHGDPHSLSHRLHIARYVALLGIPVVSSPKEAKSALDGAGICYLDADHLTPLVSLFRSLHQELGLRSLFQTAIRCVNPAFAPVSLRSYFHLGLDTVHAKVAKSVALFNPESKAVRVGIFKGVQGETEVNPRIATEITIVTGNSQQGFVLPTLLEGVIGITKFTSQLETEQIAELFLSVWQRGELISHNELIPDTQRVTQLAIASVLSSLSAIYLIKGRCQCPKVATQLALKAWNDRENKLIELAKNPLLEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ3</accession>
    <name>B1KPQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325922.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3317"/>
    <dbReference type="EnsemblBacteria" id="ACA87586">
        <property type="protein sequence ID" value="ACA87586"/>
        <property type="gene ID" value="Swoo_3317"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3317"/>
    <dbReference type="eggNOG" id="ENOG5031GBK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_997137_0_0_6"/>
    <dbReference type="OMA" id="PQTIEPM"/>
    <dbReference type="OrthoDB" id="1918605at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="31005" checksum="09B5870A3AA76897" modified="2008-04-29" version="1">MKDENIDKPAEFDDELQQLYKAQEQEVPSAELDEAILKLARAAVKKSQDDNVVIVETSFWRRHRWPLSSAASVMFVATLLLINQDVTQDILSDDVPVMMQMSEPQGELGDSDSAQPAAMDTRSYAGDKGVEAQSVQETDEMKRTAPRAMASSPQAEALPAKSSPNTAQQQSDPKVESIAISVDDIDQDVRAKIESLSSSKSAKTASQREAMVSAKQALNHLESLVEMEKWADAEKLVLKLRRNYPELRSEDHPQHLRWKALSEQVIIPLPKPKVPSSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ9</accession>
    <name>B1KPQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325928.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87592">
        <property type="protein sequence ID" value="ACA87592"/>
        <property type="gene ID" value="Swoo_3323"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3323"/>
    <dbReference type="eggNOG" id="ENOG50315IY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118469_0_0_6"/>
    <dbReference type="OMA" id="LTHEFRH"/>
    <dbReference type="OrthoDB" id="1615239at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="20167" checksum="6B202ED9F1C1CC2D" modified="2008-04-29" version="1">MKLIKILSLLLIVLTIAVAFFHKQIISGVLLPQYIDWAYEIDKKGVDTGIPLGDKELSLASDIGIKSPEKVRIVYVDEVPFPYENFALKLFGEAVGFVGEGIVNNAQVFGYSIYARNGYELNRPKLAHELVHVLQIERSSLDATVTRYFSERAQYDYEDAPLEAEAFKANEKYSDDWK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT0</accession>
    <name>PIMT_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="1">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pcm</name>
        <name type="ordered locus">Swoo_3344</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325948.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPT0"/>
    <dbReference type="SMR" id="B1KPT0"/>
    <dbReference type="STRING" id="392500.Swoo_3344"/>
    <dbReference type="EnsemblBacteria" id="ACA87613">
        <property type="protein sequence ID" value="ACA87613"/>
        <property type="gene ID" value="Swoo_3344"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3344"/>
    <dbReference type="eggNOG" id="COG2518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055432_2_0_6"/>
    <dbReference type="OMA" id="TISAIHM"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000093293" description="Protein-L-isoaspartate O-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <sequence length="211" mass="22903" checksum="CA7456B3A65BD2A3" modified="2008-04-29" version="1">MSRVATTAALNLAKSLRDAGIRDEAVLQAVANTPRELFLDAALGHKAYENTALPIGMGQTISQPYIVARMTELLLEHKPKKVLEIGTGSGYQAAILAQLSPELCTVERIKSLQIQARQRLKRLDLHNISFKYGDGWKGWPNKGPFDAIMVTAAAATVPEALLGQLVDNGVLIIPVGDTSQQLLKVVRHGEQFSSEVVEIVRFVPLVNGELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPX4</accession>
    <name>B1KPX4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87657">
        <property type="protein sequence ID" value="ACA87657"/>
        <property type="gene ID" value="Swoo_3389"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3389"/>
    <dbReference type="eggNOG" id="ENOG5032VQV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078185_0_0_6"/>
    <dbReference type="OMA" id="NTIYIEM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764737" evidence="2">
        <location>
            <begin position="23"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="307" mass="34012" checksum="D31C3BACCE9F4DCE" modified="2008-04-29" version="1" precursor="true">MMKTLQISLLIGLLSPLFSVLSEPMKTPNHQTNFYQVSFNTYQAYCFIKINGIDYLDNLGSLTGSIATGGPISSILSNGENRISIEVASLTAPQNLSFTPDASCKVSIQVYNAKGESFVTSLVATADEKLGPTGVHSPLYQGDKAMGPVTERTVKMSVLHQLSRTFIATGLPKWTWTQATPFEESEQNIQKLKSKYQELQHLFANKNLDELAKAAYIAMDEQGSVQGYSAKEFWDSFDFKKEFANGASALPINWENQSLQSYLGGRLFRFTDNNGYSPLKLGFNDNESIVSYNPYFSLVNGQIVISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPY7</accession>
    <name>B1KPY7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Yip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4851</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327417.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4851"/>
    <dbReference type="EnsemblBacteria" id="ACA89100">
        <property type="protein sequence ID" value="ACA89100"/>
        <property type="gene ID" value="Swoo_4851"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4851"/>
    <dbReference type="eggNOG" id="ENOG5031MEF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1194237_0_0_6"/>
    <dbReference type="OMA" id="VDIEWFA"/>
    <dbReference type="OrthoDB" id="1075898at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="10"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA89100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="26460" checksum="213A1C22AC730015" modified="2008-04-29" version="1">MTTVNTVLDAFVAPSALFERFEYNQRQSSIVLVILFGLILASYYLFFAGMTDEWLLAQQLGQVGDLSIQEREIAQEMMTKTLPYTWAFVGGMTIVGHLFTVLGLSAFFTLIAKVPSIGIGKFTFRDWFYFISWCQLPWIVNYIGFSFLFLSSSASDLPLSLMHYASLEQLFLNLSANDSAYGLYTTLNLFLVWSITISVLGLRKCFNMKPMMAIFISAFPYFAFFGIWFLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ01</accession>
    <name>B1KQ01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4865</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327431.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4865"/>
    <dbReference type="EnsemblBacteria" id="ACA89114">
        <property type="protein sequence ID" value="ACA89114"/>
        <property type="gene ID" value="Swoo_4865"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4865"/>
    <dbReference type="eggNOG" id="COG4555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="IMCAFLV"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="26481" checksum="944294AA348860CE" modified="2008-04-29" version="1">MIKVCNLSKKIGDVQALNNLSFEANDGQITGLLGPNGAGKTTCLRTVFGLLQADEGHAEIDGIDVAKSPIQAKQQLGLFPDPFGLYERLTPREYISYFAELNGLSRTQAKDATQKVLTELHMDDIADRRCKGFSQGQRMKTALAQAIVHQPTNIILDEPTRGLDVMSTRVLRDLLKALKEQGHCVLFSSHVMQEVAALCDQVIVMAEGKVVAVGSPDELCQQTGKDSLEDAFIQLIGTDEGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ51</accession>
    <name>B1KQ51_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4915</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327480.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89164">
        <property type="protein sequence ID" value="ACA89164"/>
        <property type="gene ID" value="Swoo_4915"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4915"/>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016813_4_2_6"/>
    <dbReference type="OMA" id="INEFFAY"/>
    <dbReference type="OrthoDB" id="437016at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018270">
        <property type="entry name" value="C_nuclsd_transpt_met_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00804">
        <property type="entry name" value="nupC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="7">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="9">
        <location>
            <begin position="99"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="8">
        <location>
            <begin position="201"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA89164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="422" mass="44587" checksum="9F2999DA4D2EA7A3" modified="2008-04-29" version="1" precursor="true">MQILISIVGIIALLSVAFLASENRKAINYRTVGLAFLLQLIMGAFVIYSSFGQAVILNMAEAVSTVIGYSNEGMSFMFGGLVSDKMYELFGPGGFVVAFKVLPIIVFFSAISAVLYYLGIMQWVVRTVGGALQKILNTSKAESMSASANIFLGVTEAPLLIKPYIPKMNRAELFAVMCGGLASIAGTMLAGYAQLGIKMEYLLAASFMAAPGGLLFAKLLIPQTEKINDQDLTVVEENPPANIIDAATTGTMNGLSLAMAVGAMLFAFVSLVALMNGMIGGIGNWFGFDGLSLQLILGYLFAPIAWLMGVTWDEALLAGSFIGQKIVINEFFAYINLAPYLNGDMIVEATGLPMSERTQVILSFALCGFANLGTIAIAIAGIGGLVPERRSEIASLGLKALFAGILSNLMAATIAGLFMSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB0</accession>
    <name>B1KQB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323114.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0467"/>
    <dbReference type="EnsemblBacteria" id="ACA84765">
        <property type="protein sequence ID" value="ACA84765"/>
        <property type="gene ID" value="Swoo_0467"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0467"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_9_6"/>
    <dbReference type="OMA" id="RYFENKD"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032551">
        <property type="entry name" value="BscR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16295">
        <property type="entry name" value="TetR_C_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="198" mass="22777" checksum="595BC2AFE3E84BAF" modified="2008-04-29" version="1" precursor="true">MDNKRELIFTATEKIIATKGIQGLSMQQIATEAGVAAGTIYRYFKDKEELISELRKHVLREVASNILVDCHEGDLEQRFKRIWFNIVEFGRQRTPANLSYEQYIHLPGIDSDPHQTYEKQTFQGLHMLFEAGRVSGQFHNLQNKVLFAISLEPSMALGRSIRRGQIEYNRDELEITCDLCWKALLTTPESTQKELSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM7</accession>
    <name>B1KQM7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thymidylate kinase</fullName>
            <ecNumber evidence="3 6">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tmk</name>
        <name evidence="8" type="ordered locus">Swoo_1982</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3 6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324612.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1982"/>
    <dbReference type="EnsemblBacteria" id="ACA86266">
        <property type="protein sequence ID" value="ACA86266"/>
        <property type="gene ID" value="Swoo_1982"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1982"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_0_1_6"/>
    <dbReference type="OMA" id="VMTREPG"/>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="7">
        <location>
            <begin position="12"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23121" checksum="0E85C6CBEBB3DBE8" modified="2008-04-29" version="1">MSKQLNSKFIVIEGLEGAGKSSAISLVRDFIEKHTGAVPVCTREPGGTPLAERIRDLVKIADETDPLCDEAECLLFYAARAQLVANVIKPALRRGEWVLGDRHNLSSLAYQGGGRGLSTLVESVSRATLGDFKPDLTIYLDIEPKLGLTRAANRGELDRIEVEEIAFFERARHTFLSYAQQDDSIQVIDAGQTMAEVHKDIVALLQAQDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQP0</accession>
    <name>B1KQP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324625.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1995"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86279">
        <property type="protein sequence ID" value="ACA86279"/>
        <property type="gene ID" value="Swoo_1995"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1995"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_0_6"/>
    <dbReference type="OMA" id="VEVNQGY"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="26681" checksum="6C58DF4AEB6C0027" modified="2008-04-29" version="1">MLTSIIIPCYNEVENLPLLVERCRQAIRHSKLEFIIVDNGSTDDTSKQLAELISADQFIHSCHVQVNQGYGFGICAGLKIAQGDILGWTHADLQTDPYDTVNASCVFECSDTPEILFVKGTRKKRPLKDNIFTIGMSICELFLHQTWLWDINAQPTLFHRKFYESWQSPPNDFSLDLYAFFLAKKSHKIKRIPVTFSDRKYGQSNWNINWRQKLKFIKRTLDFSLSLKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQS3</accession>
    <name>B1KQS3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3411</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326014.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3411"/>
    <dbReference type="EnsemblBacteria" id="ACA87679">
        <property type="protein sequence ID" value="ACA87679"/>
        <property type="gene ID" value="Swoo_3411"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3411"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_1_2_6"/>
    <dbReference type="OMA" id="DKFICKS"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="27223" checksum="E7B32E7223785A7B" modified="2008-04-29" version="1">MRLDKFLCKSTQLTRHEACELILAGKVLVNGESVVSPSAQVHENNHIRLEGGQRLTARASRYIMLHKPADTLSSNVDGDHPSVFNFINLEHTSELHIAGRLDADTTGLLLITDDGRWSFNVFNPKYHCEKVYRVYLRDSIEGEIAGEIDAELKARFKQGLDLQGEQALTLPAKLEFVSPKEVLLTITEGRYHQMKRMFARVGNRVNALHREQVGKIKLDMPVGQWRYLTREEIDSIPQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU6</accession>
    <name>B1KQU6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326037.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3434"/>
    <dbReference type="EnsemblBacteria" id="ACA87702">
        <property type="protein sequence ID" value="ACA87702"/>
        <property type="gene ID" value="Swoo_3434"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3434"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_6_3_6"/>
    <dbReference type="OMA" id="AICRYFE"/>
    <dbReference type="OrthoDB" id="1383885at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03182">
        <property type="entry name" value="GST_C_GTT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03051">
        <property type="entry name" value="GST_N_GTT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034346">
        <property type="entry name" value="Gtt2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034345">
        <property type="entry name" value="Gtt2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23978" checksum="6A6A8A7D92E1AD59" modified="2008-04-29" version="1">MKLYELAPTPSARRVNIFLAEMGIEIDRVNIDIRSGENLTDEFKAMSVNGRIPLLALDDGQTLCESVAICRYFDELHQPKNSLFGTTPIEKAKIEMWQRICELQGLFVGFQAFRNITKIFEDRENCVEAWGEESKRRLIDFLPTLETQLSQHQFIAGNSFSIADITAYAMMTFIQNLDITPSKEQVNLTRWLHEIEQRSSVQSVNAGNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQW7</accession>
    <name>B1KQW7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M61 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326058.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3456"/>
    <dbReference type="EnsemblBacteria" id="ACA87723">
        <property type="protein sequence ID" value="ACA87723"/>
        <property type="gene ID" value="Swoo_3456"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3456"/>
    <dbReference type="eggNOG" id="COG3975">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022755_0_0_6"/>
    <dbReference type="OMA" id="DWDVNPY"/>
    <dbReference type="OrthoDB" id="679125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024191">
        <property type="entry name" value="Peptidase_M61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007963">
        <property type="entry name" value="Peptidase_M61_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040756">
        <property type="entry name" value="Peptidase_M61_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05299">
        <property type="entry name" value="Peptidase_M61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17899">
        <property type="entry name" value="Peptidase_M61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016493">
        <property type="entry name" value="Glycyl_aminpptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764765" evidence="1">
        <location>
            <begin position="22"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="484"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="601" mass="67356" checksum="4A46A736D2A4A1D3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQX8</accession>
    <name>RLMM_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase M</fullName>
            <ecNumber evidence="1">2.1.1.186</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (cytidine2498-2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA 2'-O-ribose methyltransferase RlmM</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmM</name>
        <name type="ordered locus">Swoo_3468</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(2498) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(2498) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42788"/>
            <dbReference type="Rhea" id="RHEA-COMP:10244"/>
            <dbReference type="Rhea" id="RHEA-COMP:10245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.186"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.186" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326068.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQX8"/>
    <dbReference type="SMR" id="B1KQX8"/>
    <dbReference type="STRING" id="392500.Swoo_3468"/>
    <dbReference type="PRIDE" id="B1KQX8"/>
    <dbReference type="EnsemblBacteria" id="ACA87734">
        <property type="protein sequence ID" value="ACA87734"/>
        <property type="gene ID" value="Swoo_3468"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3468"/>
    <dbReference type="eggNOG" id="COG2933">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043780_0_0_6"/>
    <dbReference type="OMA" id="PVDWMVC"/>
    <dbReference type="OrthoDB" id="902245at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01551">
        <property type="entry name" value="23SrRNA_methyltr_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040739">
        <property type="entry name" value="RlmM_FDX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011224">
        <property type="entry name" value="rRNA_MeTrfase_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18125">
        <property type="entry name" value="RlmM_FDX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028774">
        <property type="entry name" value="UCP028774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000201533" description="Ribosomal RNA large subunit methyltransferase M">
        <location>
            <begin position="1"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="220"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01551"/>
        </source>
    </evidence>
    <sequence length="358" mass="40672" checksum="16B38A5C42EF1B3D" modified="2008-04-29" version="1">MINLFLYCRSGYEKECAAEIQHRAAELEIGGFVKTNKKDGYVIFQCFQAGDANILAQKIKLDSLIFARQMFAAKELLKNLPEHDRITPIMEALSDVRNAGELRVETPDTNEAKERTAFCRKFTVPLRQKLKNAGNLLKKENSSRPIIHVCFVASGTAYVGFSFSNNSSPYPMGIPRLKMASDAPSRSTLKLDEAFIHFIPEEEQEQRLSSGMNAVDLGACPGGWTYQLVRRGMFVAAVDNGPMDEGLMETGQVKHYQADGFRFEPPRKNIYWLVCDMIEKPSRVAELIEAWAINGWFKEAMFNLKLPMKSRYQDVSTILETMATVLEENEIKNFSIKCKHLYHDRDEVTVYLSLNPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR29</accession>
    <name>B1KR29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Class I peptide chain release factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323194.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0550"/>
    <dbReference type="EnsemblBacteria" id="ACA84846">
        <property type="protein sequence ID" value="ACA84846"/>
        <property type="gene ID" value="Swoo_0550"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0550"/>
    <dbReference type="eggNOG" id="COG1186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089470_3_0_6"/>
    <dbReference type="OMA" id="SEHRSQW"/>
    <dbReference type="OrthoDB" id="2047548at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="3">
        <location>
            <begin position="7"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15413" checksum="E15752B6DE390424" modified="2008-04-29" version="1">MIKISNSVSLQENEIEWQFIRSSGAGGQHLNKVSTAAQIIFDINASSLPEFYKQALLKKADHRITKSGKIIIKCQASRSQDFNRQTALEQFIELVASVAIVQKRRVATKPTKGSQRRRVDAKKQKGATKALRQNKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR48</accession>
    <name>B1KR48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323213.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0569"/>
    <dbReference type="EnsemblBacteria" id="ACA84865">
        <property type="protein sequence ID" value="ACA84865"/>
        <property type="gene ID" value="Swoo_0569"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0569"/>
    <dbReference type="eggNOG" id="COG2731">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107139_2_0_6"/>
    <dbReference type="OMA" id="FIDIQIP"/>
    <dbReference type="OrthoDB" id="1857569at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004375">
        <property type="entry name" value="NanQ/TabA/YiaL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037012">
        <property type="entry name" value="NanQ/TabA/YiaL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34986">
        <property type="entry name" value="PTHR34986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04074">
        <property type="entry name" value="DUF386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00022">
        <property type="entry name" value="TIGR00022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="17492" checksum="6686B284B289D265" modified="2008-04-29" version="1">MILDTLSNANLYSHLTPRLTKALAHLTETDFTQLEVGSYELEGKDIFVIVNDYETKPKEVEPFEVHQEYIDVQFVVSGEEEFGYLPLADQTPSRPYFAKHDYAEFDYESNKDDAAFIPFKAGMFAIFFPQDMHMPGTSATPTQVRKVVIKVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR72</accession>
    <name>B1KR72_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323237.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0593"/>
    <dbReference type="EnsemblBacteria" id="ACA84889">
        <property type="protein sequence ID" value="ACA84889"/>
        <property type="gene ID" value="Swoo_0593"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0593"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_0_2_6"/>
    <dbReference type="OMA" id="RWFIANP"/>
    <dbReference type="OrthoDB" id="1064766at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="2"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="363" mass="40001" checksum="1E2D8D4871D857FB" modified="2008-04-29" version="1">MSLFTPYKTTKLSLSNRMVMAPMTRSRTTQPGNIPNEMMAQYYAQRASTGLIITEATQISDDSQGYSFTPGVYTPEQILGWQKVTSAVHESGGKIFNQLWHVGRVSHPVFQQGLAPMAPSAIKPTDTQVWVVDAEHPDGQMVDCPVPREMTYQDIKRVVNDFADAAENAIEAGFDGVEIHGGNGYLIDQFLRTNSNHRTDSYGGSRENRTRFLMEVIAEVSQRVGADKVGVRLAPFVTFKDMDCPDIVNAILLAAEQLSQLGIAYLHLSEADWDDAPQIPANFRVKLREVFKGTIIVAGRYDTVRACEIIDSGYADLVAFGRAFIANPDLPFRLQTGKPLADFDKGPLFGGGAAGYTDYPNYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRS5</accession>
    <name>B1KRS5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3576</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326173.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3576"/>
    <dbReference type="EnsemblBacteria" id="ACA87840">
        <property type="protein sequence ID" value="ACA87840"/>
        <property type="gene ID" value="Swoo_3576"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3576"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_19_6"/>
    <dbReference type="OMA" id="KWAILTE"/>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="442"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="500"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="543"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="772" mass="84525" checksum="91F0704323C8A0EE" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD42</accession>
    <name>B1KD42_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Na(+)-translocating NADH-quinone reductase subunit E</fullName>
            <shortName evidence="10">Na(+)-NQR subunit E</shortName>
            <shortName evidence="10">Na(+)-translocating NQR subunit E</shortName>
            <ecNumber evidence="10">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NQR complex subunit E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">NQR-1 subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nqrE</name>
        <name evidence="11" type="ordered locus">Swoo_3613</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326210.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3613"/>
    <dbReference type="EnsemblBacteria" id="ACA87877">
        <property type="protein sequence ID" value="ACA87877"/>
        <property type="gene ID" value="Swoo_3613"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3613"/>
    <dbReference type="eggNOG" id="COG2209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095255_0_0_6"/>
    <dbReference type="OMA" id="YFLGMCS"/>
    <dbReference type="OrthoDB" id="1814639at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00429">
        <property type="entry name" value="NqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010967">
        <property type="entry name" value="NqrE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30335:SF1">
        <property type="entry name" value="PTHR30335:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01940">
        <property type="entry name" value="nqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="8 10 11" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="202" mass="21527" checksum="D31369A0D9AEBF56" modified="2008-04-29" version="1">MEHYISLLIRSIFIENMALSFFLGMCTFLAVSKKVTTAMGLGIAVVVVLTISVPVNQIIYQGLLAPGALAWAGAPEADLSFLKFITFIGVIAALVQILEMVLDKFFPPLYNALGIFLPLITVNCAIFGAVSFMVERDYNLAESMVFGVGSGLGFALAIVLLAGIREKLKYADVPDGLRGLGITFVTAGLMALGFMSFSGVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDB6</accession>
    <name>B1KDB6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Met repressor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Met regulon regulatory protein MetJ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0621</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MetJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012144376.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0621"/>
    <dbReference type="EnsemblBacteria" id="ACA84917">
        <property type="protein sequence ID" value="ACA84917"/>
        <property type="gene ID" value="Swoo_0621"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0621"/>
    <dbReference type="eggNOG" id="COG3060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142318_0_0_6"/>
    <dbReference type="OMA" id="KWNGEYI"/>
    <dbReference type="OrthoDB" id="1738030at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00490">
        <property type="entry name" value="Met_repressor_MetJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002084">
        <property type="entry name" value="Met_repressor_MetJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023453">
        <property type="entry name" value="Met_repressor_MetJ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01340">
        <property type="entry name" value="MetJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0678">Repressor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="104" mass="12009" checksum="F2DAA36A98DF5833" modified="2008-04-29" version="1">MTEWNGDYISPYAEHGKKNEQVKKITVSIPLKVLKVLTDERTRRQVNNLRHATNSELLCEAFLHAYTGQPLPNDEDLSKDKPDSIPAEVKRLMDEMGIEWEDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDE0</accession>
    <name>B1KDE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Curlin associated repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Fimbrium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CsgA/CsgB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323288.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0645"/>
    <dbReference type="EnsemblBacteria" id="ACA84941">
        <property type="protein sequence ID" value="ACA84941"/>
        <property type="gene ID" value="Swoo_0645"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0645"/>
    <dbReference type="eggNOG" id="ENOG502ZC9A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042034_0_0_6"/>
    <dbReference type="OMA" id="NWANNAI"/>
    <dbReference type="OrthoDB" id="890095at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009742">
        <property type="entry name" value="Curlin_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07012">
        <property type="entry name" value="Curlin_rpt"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766967" evidence="4">
        <location>
            <begin position="27"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="503" mass="53070" checksum="4FCD89F97FBE4251" modified="2008-04-29" version="1" precursor="true">MRSQTKKTILALAITAGLGMSGSAFADSATITQTTDTANSVVGQEAYIQQTQVGANANVATIDQVGDDQSATTVQEGVWLEAYTTSTGLGNNVEVDQADDWHISNVDMTGNDNETYVAQFDFYNQADIDVTGNDNNVDVAQDGSQSEAVVELIGDNNSAVINQEGDGNFGVYRVEGNDNDGDITQMGNGNTAGMVSLDITPNVGNNNDVTVYQEGDNNLGAVKGVAGDDNNFDIEQAGNDNTGFVYDLTGSDNEFEIDQEGDNNTAYMAAVQGDDNFIEIKQDGMGNTIGDTLIAEVQGDDNDLRVDQEGDNNTAQFQVFGNDNDVSLDQEGNTNVATFGAYGNDNDFELRSDGAENEVTAFAEGDDNKIEISQEGDMNFGYADLIGNGNDTDIEQDGDENEAVLTVVGMDNTDLDMTQEGDLNLIDLIIVGDENSALITQTGDGNWVGGEDDGAFVVTGDGNSLTIAQTGNDNLVMGSQTGSDHSISVTQTGDFNTATVIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDH5</accession>
    <name>B1KDH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84976">
        <property type="protein sequence ID" value="ACA84976"/>
        <property type="gene ID" value="Swoo_0680"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0680"/>
    <dbReference type="HOGENOM" id="CLU_2371222_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="95" mass="10811" checksum="26DD6661F2D97A77" modified="2008-04-29" version="1">MNVAAGDSFEYGTRCSRNSLRIQERFADSKSQVEHLSLPSSWTCSGIQFFNHLLIALSHFFTLSRLSLVVYLAVLQGGKIEQMLNFRYCCCVVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV7</accession>
    <name>B1KDV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CBS domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3699</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326291.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3699"/>
    <dbReference type="EnsemblBacteria" id="ACA87959">
        <property type="protein sequence ID" value="ACA87959"/>
        <property type="gene ID" value="Swoo_3699"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3699"/>
    <dbReference type="eggNOG" id="COG4535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_3_0_6"/>
    <dbReference type="OMA" id="QMISIKA"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="70"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="136"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="291" mass="32908" checksum="2A86C363A3EE59F9" modified="2008-04-29" version="1">MSDDIPPSTSAQKKSWLDKVSQLFQGEPQSRDDLVEVIHDAELREVISEDTREMIKGVLEVSDLRVRDIMIPRAQIVALQIDDSVTELLSTVISSAHSRFPVVNEDKDHIEGILLAKDLLQYGFKNSDEPFSLSQVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSAEETEIRKVSKLVYMIKALTPIEDFNESFNTQFSDEEFDTVGGLVSHAFGHLPERNEKVTIDGIEFTVISADTRRLLQLRVKLPDPSIEEKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE87</accession>
    <name>B1KE87_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoadenosine 5'-phosphosulfate reductase</fullName>
            <shortName evidence="3">PAPS reductase</shortName>
            <ecNumber evidence="3">1.8.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3'-phosphoadenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">PAPS reductase, thioredoxin dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">PAPS sulfotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">PAdoPS reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cysH</name>
        <name evidence="5" type="ordered locus">Swoo_0778</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + adenosine 3',5'-bisphosphate + 2 H(+) + sulfite = 3'-phosphoadenylyl sulfate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:11724"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="EC" id="1.8.4.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.8" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323420.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0778"/>
    <dbReference type="EnsemblBacteria" id="ACA85073">
        <property type="protein sequence ID" value="ACA85073"/>
        <property type="gene ID" value="Swoo_0778"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0778"/>
    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044089_3_0_6"/>
    <dbReference type="OMA" id="PIARWTQ"/>
    <dbReference type="OrthoDB" id="674332at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00206"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011800">
        <property type="entry name" value="PAPS_reductase_CysH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02057">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="4">
        <location>
            <begin position="63"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; cysteine thiosulfonate intermediate" evidence="3">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="260" mass="29514" checksum="15ABFE95817688C3" modified="2008-04-29" version="1">MSSTIMPESSSIDSIVSSDEILALLSAPEVEQKGELERINQFLAELTPAQRIAWALQYLPGNHALSSSFGIQGAVMLHLVSSQKADIPVILTDTGYLFPETYRFIDELTERLSLNLKIYSSKYTPAWQEARFGQLWEKGLDGLDQYNRMNKVEPMQRALTDNEVGTWFAGLRRSQSSTREALPILAIHGTRFKILPILEWSNKEVHEYLTEHDLPYHPLWDQGYVSVGDTHSSKPLELGMSEEDTRFNGLKRECGLHFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF0</accession>
    <name>B1KEF0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324871.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2247"/>
    <dbReference type="EnsemblBacteria" id="ACA86528">
        <property type="protein sequence ID" value="ACA86528"/>
        <property type="gene ID" value="Swoo_2247"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2247"/>
    <dbReference type="eggNOG" id="COG3287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047108_1_1_6"/>
    <dbReference type="OMA" id="THHILPR"/>
    <dbReference type="OrthoDB" id="1942718at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019494">
        <property type="entry name" value="FIST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013702">
        <property type="entry name" value="FIST_domain_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08495">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10442">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00897">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01204">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FIST" evidence="1">
        <location>
            <begin position="30"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="FIST_C" evidence="2">
        <location>
            <begin position="233"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="42645" checksum="8B23C3FFBA325D1B" modified="2008-04-29" version="1">MTRIKTKYAVSRDDNPQQASLEIFEQLGQPQDGFVLFYCSVVYPLDTLAKAMSKQFNSVELAGCTTAGELTCEGYEQHSIVAIWFSPDYFAVSAELIDSIETFSLITAQTKVNRLLETCSSKQLTEIKNNTFMLTLIDGLSTKEEQLLSILNSAANGIPHFGGSAGDDINLANTHVYHQGKFVQQAAIVIMVNTLCQFEVFNCNHIKSSIEKLVVTAADAKSRTVYELNSEPAALEYARFLGVDINDLSPEIFSLHPLAVKIGGNYYIRSIQKVNKTDLSLTFYCAVDEGIVLSAVEMSNIITSLSGKLETLEQRFDKPELVLACDCFLRRLEIEQRALNDEIKQLQKQYRIFGFNTYGEHINGMHLNQTFTGVYISGELNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEM7</accession>
    <name>B1KEM7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326373.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3783"/>
    <dbReference type="EnsemblBacteria" id="ACA88042">
        <property type="protein sequence ID" value="ACA88042"/>
        <property type="gene ID" value="Swoo_3783"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3783"/>
    <dbReference type="eggNOG" id="ENOG502Z88X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109349_0_0_6"/>
    <dbReference type="OMA" id="EVFFCGY"/>
    <dbReference type="OrthoDB" id="2037718at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="217" mass="24382" checksum="CDD44F51421A48D3" modified="2008-04-29" version="1">MSEVNETIVVGTGAIIERLLKGEFICRTTDEESWRALKNPSTRERVETYLNQINRTIGSAGEGEVFFCGYQQLGDSERKVISSQFKDICNALIPLVEWLVLVQEASGQDAPLSEGAAVRLTELQTRIEDTPAFREQLAKISHYRLFGSTSTNVDAQIKLVFKRLVELGYLARPNAEKQIFIATGKLDYLYEVIRFIDETEGLSLEAQAETATQRDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN8</accession>
    <name>B1KEN8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="2">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="2">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326384.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3794"/>
    <dbReference type="EnsemblBacteria" id="ACA88053">
        <property type="protein sequence ID" value="ACA88053"/>
        <property type="gene ID" value="Swoo_3794"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3794"/>
    <dbReference type="eggNOG" id="COG1514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081251_2_1_6"/>
    <dbReference type="OMA" id="AARNGCY"/>
    <dbReference type="OrthoDB" id="1696971at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014051">
        <property type="entry name" value="Phosphoesterase_HXTX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02834">
        <property type="entry name" value="LigT_PEase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 1" evidence="2">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="199" mass="22566" checksum="A7BC41B5C6CA2720" modified="2008-04-29" version="1">MKRLFLGIAPTQTQNRQLSALQAGLSLDGKSISPKNFHMTLAFLGQLDIHQQFKLQHKLDILHASKALSWPRFTVTLDTLTLWRKPQILCLSGKILDPNLQYILDECHSLLQQVGIKLPHHQHIKATQNSLPQEVNFVPHISLFRKAKQLPIMREAIALTLCPKKIHLYVSVSKPTGVEYQILQSWPFAEITGKKNAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ5</accession>
    <name>B1KEQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326401.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3811"/>
    <dbReference type="EnsemblBacteria" id="ACA88070">
        <property type="protein sequence ID" value="ACA88070"/>
        <property type="gene ID" value="Swoo_3811"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3811"/>
    <dbReference type="eggNOG" id="COG4278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124467_0_0_6"/>
    <dbReference type="OMA" id="CHKHKTD"/>
    <dbReference type="OrthoDB" id="1487865at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="22204" checksum="7C3F9D1A5E0E0CC5" modified="2008-04-29" version="1">MDKTTLSEVLAYSNPAVEKRFMNIYGTDEAATSVIFNSAKKWLWLCYQRRQLGLDVKLSIDTPLLVIDEMWHNFILFSNDYLSFCKRFFGHYIHHMPTTKAMEKELKDSMQGKEPQVFAQEMLAKKRWQYEFVYDQLGKEEFLLWYKEYPKKYTPNTLLNLALEHQKLVNKEVVLIPELAQFTQKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET0</accession>
    <name>B1KET0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3836"/>
    <dbReference type="EnsemblBacteria" id="ACA88095">
        <property type="protein sequence ID" value="ACA88095"/>
        <property type="gene ID" value="Swoo_3836"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3836"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="NSRAHVM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0798">TonB box</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="STN" evidence="7">
        <location>
            <begin position="85"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1097" mass="120108" checksum="13653A5614119800" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEY2</accession>
    <name>B1KEY2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0838</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323480.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0838"/>
    <dbReference type="EnsemblBacteria" id="ACA85133">
        <property type="protein sequence ID" value="ACA85133"/>
        <property type="gene ID" value="Swoo_0838"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0838"/>
    <dbReference type="eggNOG" id="COG3235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081268_1_0_6"/>
    <dbReference type="OMA" id="VYIFCSG"/>
    <dbReference type="OrthoDB" id="2027652at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002751">
        <property type="entry name" value="CbiM/NikMN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01891">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="26369" checksum="25E44BB1ABAE991A" modified="2008-04-29" version="1">MKDFLARTVNELDWNSGPEQLIFMGLLLLWLWLIWPSDEFKALLTDKAKQTQILLASVALNALWLLNANVTQGIHVHFLGLVTLMLMYGWRMASVISILPVLFFTIFVIKSPFDFAIYGLLGINLPLFLCFIVYSQIFKYLPHHLFVYIFGGAFINAFLSIVFHILLWAAWLWLSTDYDWAFLRDNYLLIIPLLGFPEALLNGMAITLLVVYRPQWLYDYSDSTYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFR5</accession>
    <name>B1KFR5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ion transport 2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323578.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0938"/>
    <dbReference type="EnsemblBacteria" id="ACA85231">
        <property type="protein sequence ID" value="ACA85231"/>
        <property type="gene ID" value="Swoo_0938"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0938"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054901_0_0_6"/>
    <dbReference type="OMA" id="MRRHQMP"/>
    <dbReference type="OrthoDB" id="1482194at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="246"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="327" mass="37281" checksum="127248C5BCFDB6BE" modified="2008-04-29" version="1">MNEKTPTCCYHEDEGFSCTEPAEPSGLCYWHDPKILKNKPDDVQKLEKFAREGGMLRGIALKRAKLPGIDLVRHHQKTGFDMTHAELYRADLQGAHLFNLNLQNASLMKADLRDSNVHCANLVGSNLLGIKWNGAKIENIVTGKKIKQEILAHQADRVGEREIANDYFEQAEEIYRDLRKAAEREGLFAMSGEYIRKELTMRRHQMPLYSYKRMVSKVIDVFCGYGEAPMRVIGFSMGLIMVCAMLYFFTGLSYDSQLHKFQVSNDFQTNFYLFFNCIYYSVVTFTTLGYGDFTPVGLSKVIAAIEAFTGSFTIALFVVVFVKKMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW3</accession>
    <name>B1KFW3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0986</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323626.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0986"/>
    <dbReference type="EnsemblBacteria" id="ACA85279">
        <property type="protein sequence ID" value="ACA85279"/>
        <property type="gene ID" value="Swoo_0986"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0986"/>
    <dbReference type="eggNOG" id="COG0722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_6"/>
    <dbReference type="OMA" id="DINTGLR"/>
    <dbReference type="OrthoDB" id="853329at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="44"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="352" mass="39062" checksum="52999CBC88F5C3B9" modified="2008-04-29" version="1">MYYKNDDVRINKIKELLPPIAILERFPATENASATVFNARDNIHHILRKNDDRLLVVVGPCSIHDPVAALEYGRKLVKLREQYKDQLEIVMRVYFEKPRTTVGWKGLINDPDMDNSFKLNDGLRTARKLLLDLNDMGMPTAGEFLDMITPQYVADLMCWGAIGARTTESQVHRELASGLSSPVGFKNGTDGTIKVAIDAIGAASAPHHFLSVTKFGHSAIVETKGNADCHIILRGGKEPNYSAEHVSEIKQQLDKAGLDLNIMIDFSHANSAKQFKRQLLVGEDVAGQLSKGDKAIFGVMIESNLIEGRQDYIPGEPLCYGQSITDACIGWNDTESLLETLNQSVKVRRDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG02</accession>
    <name>B1KG02_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325051.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86709">
        <property type="protein sequence ID" value="ACA86709"/>
        <property type="gene ID" value="Swoo_2431"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2431"/>
    <dbReference type="eggNOG" id="ENOG503077T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060504_0_0_6"/>
    <dbReference type="OMA" id="FTNENRI"/>
    <dbReference type="OrthoDB" id="386236at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="351" mass="40301" checksum="AAA472B3CEA619BB" modified="2008-04-29" version="1">MVKPSDIKDILKKRGVYSSSNEKKTLGPILVKSGISPEEFESLKESIQTKEENPKVQSRKLKWESDDSLIEAIPHNFDFSNLVDDPFGVLSIDNAPVFTVAGDGTNTNHLIAEVTLKRNDKTKNFGDDVTYHQCSIELRIDDDKNVSLNVLTKHSSKETLNLVNKVTRRIHNHLKDNGYVSNEPIEKILFGNFTNENRIDFLVAMAKSNEKYLYYKDMKKVHMSPDEDVKGVVPTEIELFEKKVNDLMFKGKNLDSSVYLKKNALKKHIKLCSVTSRYELDDNEHQGSCLVRIHFPEFDDDSELLMEVENLNIQKKLPAELKSDIKLQILKFLETKKMTLYTKYSKKQSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG36</accession>
    <name>B1KG36_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UMUC domain protein DNA-repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2466</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325085.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2466"/>
    <dbReference type="EnsemblBacteria" id="ACA86743">
        <property type="protein sequence ID" value="ACA86743"/>
        <property type="gene ID" value="Swoo_2466"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2466"/>
    <dbReference type="eggNOG" id="COG0389">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012348_3_0_6"/>
    <dbReference type="OMA" id="ELNGQVC"/>
    <dbReference type="OrthoDB" id="442163at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025188">
        <property type="entry name" value="DUF4113"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13438">
        <property type="entry name" value="DUF4113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0741">SOS mutagenesis</keyword>
    <keyword evidence="3" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="UmuC" evidence="4">
        <location>
            <begin position="2"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="417" mass="46713" checksum="819F32CE909794CF" modified="2008-04-29" version="1">MFALVDANSFYCSAEQVFRPEWRGRPIIVLSNNDGCIVAANRQAVESGIPKFEPYFKIKAQCERLGVIALSSNYELYGSLSVRLMEVIGRFAPEQHIYSIDESFLSFERSYPAIPCLIEHGHKIRRAVWKETRLPVSVGIGSTLTLAKAANHAAKKQEGYQGVCVMDNPFQQKEILLKMLPSDVWGIGRRLAKQLDMMGVKNAYELSQMAPSLVKKQFNTEVERTVRELNGEICKGWDQVRADKQQIFSTRSVGNRITDLNALQQALSTHIGIATSNARAQGSLCSVLLVFASSSPFDSKPSSFKHTQRFAYPTNDTGELTRVANQVAAEKFRSGVRYYKIGVGLIDLVNEKHLQQDLFAPTVDPALMKVYDSLNLKYGPDSLFMAAQGSSPTWGMKRQYLTPQYTTCWNDLPKVQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG41</accession>
    <name>B1KG41_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2471</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2471"/>
    <dbReference type="EnsemblBacteria" id="ACA86748">
        <property type="protein sequence ID" value="ACA86748"/>
        <property type="gene ID" value="Swoo_2471"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2471"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_47_1_6"/>
    <dbReference type="OMA" id="FNIICVV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="12"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="419" mass="44889" checksum="9806E6441B73A129" modified="2008-04-29" version="1" precursor="true">MNSLENTKYFLFLSYLALLSMLGFIATDMYLPAFKAIEDTMQASPAQVASSLTCFLAGLAIGQLLYGPLVQRIGKRNSLLLGLVIFAVASFALASSETVLSFNIARFFQALGACSAGVIWQAIVIEKYDSIKAQNVFSNIMPLVALSPALAPLLGAFILDISSWQSIFLLLTVLAVALMLLTLAFVPKEKAAHSDDVAVAPISYLGLLKNPKYLGNVIIFGACSGAFFAYLTVWPIVMEQHGFAAKEIGLSFIPQTIMFIVGGYASKILIRKVGAEKTLTIMLVCFGLCVLSIVLSSLVFKADSILPLLTAFSILAAANGAIYPIVVNCALQEFTKNAAKAAGLQNFLQMSIAFGASSLVALWAASGEVAIGWGILSCAILVLVGYKLRVNSSWSEVKNHFTTPDPARIALEQDKLNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG90</accession>
    <name>B1KG90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3970</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326557.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3970"/>
    <dbReference type="EnsemblBacteria" id="ACA88227">
        <property type="protein sequence ID" value="ACA88227"/>
        <property type="gene ID" value="Swoo_3970"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3970"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_8_3_6"/>
    <dbReference type="OMA" id="KRNLRGY"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="9">
        <location>
            <begin position="7"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="44614" checksum="E85C7DADCC8CA387" modified="2008-04-29" version="1">MLSTKTYDVAIVGGGMVGLATAIGLAMESLRVVVIDAGETQTVTGSPKLRVSAINKASQRLLQNIGAWPYLDEGRLSPYQKMAVWDKDSLGKISFDAHSLSEQYLGSIIENDNIAHALVKRAAEFDEITHIENHKLEKIAFGEREAWLTLDNGDNVSAALVIGADGANSWVREQCKIPMTFWDYGHHAIVATVRTEIPHQDTARQVFLKDGPLAFLPLYENNLCSIVWSVPPAKAQQLLEGDKQAFERTLTAEFDGRMGMCQLECDPQAFPLRMRYARHFARHRLLLAGDAAHTIHPLAGQGVNLGFLDAAAIIQTLSELKLEGKDLGDYSNLRALERWRKADALEMIAGMEGFKRLFEGSHPVKKALRDFGLNLVDNFSPAKTLFMQQAMGNKTGLPDLCKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB3</accession>
    <name>B1KGB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3993</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326579.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3993"/>
    <dbReference type="EnsemblBacteria" id="ACA88250">
        <property type="protein sequence ID" value="ACA88250"/>
        <property type="gene ID" value="Swoo_3993"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3993"/>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_8_1_6"/>
    <dbReference type="OMA" id="DMHATVH"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="22"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="93"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="177"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="486" mass="54383" checksum="9C7519962C5613E1" modified="2008-04-29" version="1">MAKTKAQVVSLQSEFLPENQLILNAVSEGIYGFNLAGNAVFINPAAERMTGWKAEELLGKNIHNCHHHSHSDGSHYPKEDCPIYNTLNDGIAREISHEVFWRKDGSSFPVHYTSTPVYKDGKMMGVVAIFRDISIQKQTEKSLREALEQVQALSETLSSENQYLQLELADRTGDVGISGNSPKIKQLIQQIKLVANTESTVLISGENGTGKELVARNLHKLSKRADKPLVCVNCAAFSAGLLESELFGHEKGAYTGATNRRKGRFELANKGTLFLDEVAELSLEAQSKLLRVIQEQEFERVGSSETIKVDIRLITATHHDLLKRVEQGLFRMDLYYRLNVFPIQVPALRDRLSDIPELVSHLIQDLNRKLGKKITRVSQQGLKKLMLHTWPGNVRELQNVLERETILSQSPVLKLAQLPAIQAPQQKQSSNSTNQTLAEMEKKHITRVLQQTKWRISGALGAASALGLPPSTLRSRMKKLNIERPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE0</accession>
    <name>B1KGE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326606.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4021"/>
    <dbReference type="EnsemblBacteria" id="ACA88277">
        <property type="protein sequence ID" value="ACA88277"/>
        <property type="gene ID" value="Swoo_4021"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4021"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_555360_0_0_6"/>
    <dbReference type="OrthoDB" id="1646604at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="491" mass="54731" checksum="735833BD933D93E6" modified="2008-04-29" version="1">MNNFHSNSSKLCSRLKINNASIGSCVVLKTPKRVVAISCAHVIYGEEHETTIVDANQITVEIDGTAHICSKILSPLADSKATDMVVIELADTTLLSTSSLCELKVCLDVNESILGYKQAMVLLPIQDSCHSVVSLTKFNKEVDEHSFQVEVHKQTFVDYDKGAAGAAAFKGISGSGLFVDMNDSIYLAGILSKLPKSSVASTVVFQSLKPLTSILPELKESISLKKGTSSTPGDINDVCFVNYTGRSQKYYQERACDRDFCSNIKHNRNIWLSGDSGTGKTAILLRNLIDNKVNYIYCDLQPVEISSPLDIWQGVIEDVESHTEKKFENKEFTVKFMTKYLLSCNFKSDTILVIDEMSCSKKDIIEDFCKDAIALVSYYIKQSKTKNLTFVISSIFSPSKTEFNYGKFLESFDNLSSNEWTDSISNLFDIQNSSLGNRITPEGKELILSHCGSLPRLLTLIISRIYRANDFEISSIHQACKKLTKEYYEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM9</accession>
    <name>B1KGM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS116/IS110/IS902 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1064</name>
        <name evidence="3" type="ordered locus">Swoo_4722</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908</strain>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323703.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85357">
        <property type="protein sequence ID" value="ACA85357"/>
        <property type="gene ID" value="Swoo_1064"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88972">
        <property type="protein sequence ID" value="ACA88972"/>
        <property type="gene ID" value="Swoo_4722"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1064"/>
    <dbReference type="KEGG" id="swd:Swoo_4722"/>
    <dbReference type="eggNOG" id="COG3547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036902_1_0_6"/>
    <dbReference type="OMA" id="YFMLKNQ"/>
    <dbReference type="OrthoDB" id="655500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="12"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="39741" checksum="7929AD60BDE544E0" modified="2008-04-29" version="1">MRFYNNSHPYYCGIDLHARLLYVCIIDSKGKVAVHKKIDADKGDLLRILEPYIGNVIVGVECMHCWYWVSDWCAELGIDFVLGHALYMKAIHGGKTKNDKIDSFKIASLLRGGNFPIAYNYPNEMRAARDLLRRRMKIVRHGAMLKAHVVNTNSQYNLPATELNLKNISARQKLRQQYKDPIVQRNIDLDMALLDCYAKELAQVEWFIEKQAKNHNPVYLELLKTVPGIGKILSLTILYEIGDVTRFESVQKFASYSRLVKCKAESAGKTYGTNGNKIGNAHLKWAFSEAAVLYLRGNDKARNYLNRLQKRMSKAKALSALAHKLGRCVYFMLKNKTVFDEQRFLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN9</accession>
    <name>B1KGN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c, class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323713.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1074"/>
    <dbReference type="EnsemblBacteria" id="ACA85367">
        <property type="protein sequence ID" value="ACA85367"/>
        <property type="gene ID" value="Swoo_1074"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1074"/>
    <dbReference type="eggNOG" id="COG3474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106310_1_0_6"/>
    <dbReference type="OMA" id="KLWGDGW"/>
    <dbReference type="OrthoDB" id="1212262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032033">
        <property type="entry name" value="Cytochrome_P460"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038142">
        <property type="entry name" value="Cytochrome_P460_sp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16694">
        <property type="entry name" value="Cytochrome_P460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767043" evidence="1">
        <location>
            <begin position="25"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_P460" evidence="2">
        <location>
            <begin position="41"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20208" checksum="5064F2E6902A6B06" modified="2008-04-29" version="1" precursor="true">MKATCFNSIYAALILIGLATPVLAQEIFSPSVDKSGNISFPADYRSTMEHLGSWFVPTGGASGFHHVYTEMESVEYFQKNGVFPDGAVLVKELLVSEANNYTTGEGVHSANGEYKQWFVMVKDSQNRFTDNPVWGDGWGWALFKPGNTSKNLATDYKKDCLACHVPAKGTDWIYTQAYPALSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGR9</accession>
    <name>B1KGR9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2511"/>
    <dbReference type="EnsemblBacteria" id="ACA86788">
        <property type="protein sequence ID" value="ACA86788"/>
        <property type="gene ID" value="Swoo_2511"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2511"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077369_1_0_6"/>
    <dbReference type="OMA" id="APKTDLN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764860" evidence="2">
        <location>
            <begin position="28"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="29947" checksum="A7E5B96D8266CF98" modified="2008-04-29" version="1" precursor="true">MRFKRTFTLGLSLLLGLFSACYFSAIAREDTNMKAELFFEPNMVQLLKSIQADDISTAKQLIAEGVELNILGNEEITPLLWLITQTNDLKATQRALDLGADPNFSDGDGDNAVTLVARDYAPEWLEMLLEAGGNPNSIDSDGMPAMFDAIGGENWDNINTLLEYGADVNLKDRSGSNSALYPTYIMKYEFAYFFLLKGADPYIYDDTGSDLAWSVYEPIEDGIIAPDSFNYPWVMKIKQHLIDQGVKFPPPTPQEVRAMWEKNGRPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX1</accession>
    <name>B1KGX1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lactoylglutathione lyase</fullName>
            <ecNumber evidence="5">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aldoketomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glyoxalase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ketone-aldehyde mutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Methylglyoxalase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">S-D-lactoylglutathione methylglyoxal lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_2563</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-S-lactoylglutathione = glutathione + methylglyoxal</text>
            <dbReference type="Rhea" id="RHEA:19069"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="ChEBI" id="CHEBI:57474"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="4.4.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glyoxalase I family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325181.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2563"/>
    <dbReference type="EnsemblBacteria" id="ACA86840">
        <property type="protein sequence ID" value="ACA86840"/>
        <property type="gene ID" value="Swoo_2563"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2563"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_8_1_6"/>
    <dbReference type="OMA" id="NWGTESY"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="12">
        <location>
            <begin position="3"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="14865" checksum="27DD19C5C03F01E4" modified="2008-04-29" version="1">MSQLLHTMIRVTNLEASIEFYTQVLGMKLLRKSENSEYRYTLAFVGFSDEASGSAVIELTYNWDTDSYDHGNAFGHLAIGEEDIYARCKAIEAAGGKIIRAPGPVAGGSTEIAFVEDPDGYKIEFIQMSSAQKGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH04</accession>
    <name>B1KH04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326645.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4060"/>
    <dbReference type="EnsemblBacteria" id="ACA88316">
        <property type="protein sequence ID" value="ACA88316"/>
        <property type="gene ID" value="Swoo_4060"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4060"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_11_2_6"/>
    <dbReference type="OMA" id="ILCPTDY"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="15829" checksum="24353D323D585880" modified="2008-04-29" version="1">MRTRQILCPTDFSETASHALRYAIEMANFYQVGLRLIHVVDQPVGAENYQILAITPEELAKSMEDAAADKMRHLLSDLKSELPMETVIRRGSPIEEILADAVEFDVGMIVMASHGRSGLSHFLHTNVAEGIANRAKCPVLVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH35</accession>
    <name>B1KH35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4091"/>
    <dbReference type="EnsemblBacteria" id="ACA88347">
        <property type="protein sequence ID" value="ACA88347"/>
        <property type="gene ID" value="Swoo_4091"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4091"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686762_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="401" mass="42459" checksum="28F43BCA6C989C1F" modified="2008-04-29" version="1" precursor="true">MKNSNKKDALNCISRRNFLSGSISIALLTGISLTSIKSMAKAVNLDSSLLLTIIKHELSGFNGELLDPITGNYQLGQGYRFYNPILMRFQSPDSMSPFGEAGLNVYAYCHGDPVNFNDPTGHLDGWKIGFGIFAVVTGIIGAVLAPFTGGTSFAVAMGVVSGVLGAIGGSLTIASAAVEDSNPTAAANLDIASIVFSVASIAAGVSGALKGTVSGFKSRFSTSNFKTTSKLKIGKSAKARNDKFFTKIKDNAFKEVDARSGALSVESADTVMATKLESHVVGQRDLSSKFISMKPKVQYKPTRFLNNTMAWKVENVAKTGMNSGHFARSFAGALVRQGLSMSSGSFLAASKLVTARDKLDNINENNNTDTPQAPGTFGQIQATFSLDTDIVNRQIRNGIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH36</accession>
    <name>B1KH36_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326677.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4092"/>
    <dbReference type="EnsemblBacteria" id="ACA88348">
        <property type="protein sequence ID" value="ACA88348"/>
        <property type="gene ID" value="Swoo_4092"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4092"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002146_1_0_6"/>
    <dbReference type="OMA" id="TDYQYGS"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1267" mass="144521" checksum="8C7444D35CC2CFE6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH42</accession>
    <name>B1KH42_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TM2 domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4098</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326683.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4098"/>
    <dbReference type="EnsemblBacteria" id="ACA88354">
        <property type="protein sequence ID" value="ACA88354"/>
        <property type="gene ID" value="Swoo_4098"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4098"/>
    <dbReference type="eggNOG" id="COG2314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081297_5_1_6"/>
    <dbReference type="OMA" id="QKLAIWF"/>
    <dbReference type="OrthoDB" id="1687355at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="6">
        <location>
            <begin position="52"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="14200" checksum="BE0E11287C07E7BE" modified="2008-04-29" version="1">MKTRDYPLSQLKESLCTQCSQKIDSSLVTCPECHATQGLEALAGVDPNIHIKNQKLAIWFSFLLGGLGIHRFYLGQYMKGSLYLVFSWTLVPVLVGWVDAIRTLNMSPFNFAQRYSRKVERHYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHC5</accession>
    <name>B1KHC5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323779.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1140"/>
    <dbReference type="EnsemblBacteria" id="ACA85433">
        <property type="protein sequence ID" value="ACA85433"/>
        <property type="gene ID" value="Swoo_1140"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1140"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022247_1_0_6"/>
    <dbReference type="OMA" id="RRDTPFW"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033856">
        <property type="entry name" value="Trp_halogen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011396">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="500" mass="56812" checksum="272FBBEEFF6734FC" modified="2008-04-29" version="1" precursor="true">MDNKIKKVVIAGGGTAGWMTAAALSKLMGKHLDIVLVESDEIGTVGVGEATIPTLHIFHRLLGLKEQEVMAATNATFKLGISFENWKELNQSYLHSFGFLGKDCWACGFQHFWLKGKKQGIASEIGDYCTEHVAAREGRFAILPNQDQNHAYHMDASLYAKYLRKFAEQHGMSRIEGKIADVLQHQDSKSNSNGHIKALVLESGQVINGDLFIDCTGFKALLIEQTLNTGFEDWSHWLPCDSAIAVQTEATNSPIPYTRSIAHQSGWQWRIPLQNRTGNGMVFCSKFISDDDATQQLLSNIEGEPINKPRVIKFKTGTRRLHWHKNCVAIGLSSGFLEPLESTSIHLIQRSIIRLMQLFPTQEFAQQNTDEFNAQTKFEMDNIRDFIILHYKATNRDDSRFWRYCKEMSIPDSLRHRIEMFNETGNIYKFGNELFGESSWIQVMIGQGIMPKEYHSIVDSMEDEELTSFLHQIKSAAKRKVETLPPHFDFVQHYCKSTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE0</accession>
    <name>B1KHE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GatB/YqeY domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323794.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1155"/>
    <dbReference type="EnsemblBacteria" id="ACA85448">
        <property type="protein sequence ID" value="ACA85448"/>
        <property type="gene ID" value="Swoo_1155"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1155"/>
    <dbReference type="eggNOG" id="COG1610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079430_2_2_6"/>
    <dbReference type="OMA" id="AMGAVMK"/>
    <dbReference type="OrthoDB" id="1498741at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="15992" checksum="9BC3143C0C3D5F3A" modified="2008-04-29" version="1">MSLVDQLKDQMKQAMRAKEKVSLGTIRMALAAIKQIEVDTRETLTDDQAIAVLTKMVKQRRDSIAQYSAAGRDELAAIEADEIKVLEDFLPQPLSEEEIAQLVDASITEMGASSMADMGKVMGALKPKVLGRADMAAIGAMIRAKLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE6</accession>
    <name>UPPP_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="1">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">uppP</name>
        <name type="ordered locus">Swoo_1161</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text>Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323800.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHE6"/>
    <dbReference type="SMR" id="B1KHE6"/>
    <dbReference type="STRING" id="392500.Swoo_1161"/>
    <dbReference type="EnsemblBacteria" id="ACA85454">
        <property type="protein sequence ID" value="ACA85454"/>
        <property type="gene ID" value="Swoo_1161"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1161"/>
    <dbReference type="eggNOG" id="COG1968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060296_1_0_6"/>
    <dbReference type="OMA" id="IEGPFRD"/>
    <dbReference type="OrthoDB" id="1826154at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00753">
        <property type="entry name" value="undec_PP_bacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0046">Antibiotic resistance</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000197405" description="Undecaprenyl-diphosphatase">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <sequence length="266" mass="29036" checksum="A73B14DF86DB1CC8" modified="2008-04-29" version="1">MDTFQVIILALIQGLTEFLPISSSAHLILPSQILGWEDQGLAFDVAVHIGSLLAVVLYFRKEVVSLLTSWLASIFKGQKSDDSKLAWWIILATLPAVILGFALKDMIEVYLRGPGVIAITTVLFGLLLWWADRMSRCELTEYQTGWKKALLIGFAQALALIPGTSRSGATITAALMLGLNREAAARFSFLMSIPVILGAAILMSKDLFESGHVIDYSSLALGVGVSFVAAYTCIHLFLKIISRMGMTPFVIYRLALGALLCAFIFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ0</accession>
    <name>B1KHQ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325275.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86935">
        <property type="protein sequence ID" value="ACA86935"/>
        <property type="gene ID" value="Swoo_2659"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2659"/>
    <dbReference type="eggNOG" id="ENOG5031A2U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1440160_0_0_6"/>
    <dbReference type="OrthoDB" id="1555311at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008983">
        <property type="entry name" value="Tumour_necrosis_fac-like_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49842">
        <property type="entry name" value="SSF49842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764886" evidence="1">
        <location>
            <begin position="26"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="20415" checksum="DB1E7C6AF4480083" modified="2008-04-29" version="1" precursor="true">MKKLNVLVALFTAGLALFVASSAQATWIPNHQVVVDAHISGSELTEANNGKIKVVEYNTATINFNTSFDTNSHIFTAPATGLYNVDARYAQLKCGSRYLLRIGISIPNATPPGGNASLGPVTFAEIPNFGCAIPGIAAVNGVMHLEEGDTLFIQGRYQQAIYDISRWSYKNEYQNRLVITYLGVPTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ5</accession>
    <name>B1KHQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2664</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325280.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2664"/>
    <dbReference type="EnsemblBacteria" id="ACA86940">
        <property type="protein sequence ID" value="ACA86940"/>
        <property type="gene ID" value="Swoo_2664"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2664"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_396321_0_0_6"/>
    <dbReference type="OMA" id="ENIFPRT"/>
    <dbReference type="OrthoDB" id="505922at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="138"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="178"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="468"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="260"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="695" mass="80001" checksum="54BE83F2B2F58D68" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHW3</accession>
    <name>B1KHW3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326770.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4185"/>
    <dbReference type="EnsemblBacteria" id="ACA88441">
        <property type="protein sequence ID" value="ACA88441"/>
        <property type="gene ID" value="Swoo_4185"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4185"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_0_6"/>
    <dbReference type="OMA" id="VQMAEYV"/>
    <dbReference type="OrthoDB" id="1435073at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="2">
        <location>
            <begin position="101"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="308" mass="34371" checksum="CA9B4C3C9BEC3218" modified="2008-04-29" version="1">MRHKLLLLTSKNERYRELLASCHLPEIVLLGDEPSSILEANVWLAEPALAAPLLPHANNLTWMQSTMAGVDALVKPRQRKDYQLTNVRGIFGPLMSEYLFGYLLAHQREHQKYKTQQAEKIWLPGSFKTLQGQNLLLLGTGNIAKHLAQTAKHFGMHVTGINRGAKPTKGFDKVDTLANISQHLAQADAVASILPSTPQTRGALNAELLSMMKPGAIFFNLGRGDVLDLDALYMQLIENSDQHAILDVFNQEPLPKEHPIWTLDNVIITPHIAAPSFPEQVVEIFSNNYHKLLQGEQLTHAVNFARGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHX7</accession>
    <name>B1KHX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326784.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4199"/>
    <dbReference type="EnsemblBacteria" id="ACA88455">
        <property type="protein sequence ID" value="ACA88455"/>
        <property type="gene ID" value="Swoo_4199"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4199"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_2_6"/>
    <dbReference type="OMA" id="TQLGLCP"/>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="26994" checksum="7F20FB3BE22B1C1C" modified="2008-04-29" version="1">MSTIQVQDEQGVRIITINRPEKRNALSLEMYTSLTEYLIQGESDNAIHAFLIKGQAECFTSGNDVADFLTNSNLDAEHPAFRFLFTLLDLTKPIVAAVTGAAVGIGTTLLLHCDLVYAAPSAKFQLPFINLALVPEAGASLLLPQLVGLQKASELLLLGESFGPETAKSLNIINELVPGDKVFEHSLSKAKKLASQPPQALQATRALLRPNKEQIRDQMKMELKEFETRLKSDEAKMRFQAFLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI21</accession>
    <name>B1KI21_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aquaporin Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">aqpZ</name>
        <name evidence="11" type="ordered locus">Swoo_1206</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell inner membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323845.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1206"/>
    <dbReference type="EnsemblBacteria" id="ACA85499">
        <property type="protein sequence ID" value="ACA85499"/>
        <property type="gene ID" value="Swoo_1206"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1206"/>
    <dbReference type="eggNOG" id="COG0580">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020019_3_2_6"/>
    <dbReference type="OMA" id="IFKALMY"/>
    <dbReference type="OrthoDB" id="1744995at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01146">
        <property type="entry name" value="Aquaporin_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023743">
        <property type="entry name" value="Aquaporin_Z"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45724">
        <property type="entry name" value="PTHR45724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 1" evidence="10">
        <location>
            <begin position="65"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 2" evidence="10">
        <location>
            <begin position="187"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="site" description="Involved in tetramerization or stability of the tetramer" evidence="10">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="23855" checksum="E6D625AEF8DD81A9" modified="2008-04-29" version="1" precursor="true">MNMTQKMAAEFIGTLWLVLGGCGSAVIAAAFPEVGIGLLGVAFAFGLTVLTMAYAVGHISGCHLNPAVSFGLWAGGRFPANELIPYIIAQVAGGIAGAGILYLIASGNADFSLADGFASNGYGAHSPGGYTMTSALVTEIVMTLFFLLIILGATDARAPQGFAPIAIGLGLTLIHLISIPVTNTSVNPARSTGPALFVGDLAISQLWLFWVAPIAGAIIAGFIYKFFNTKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI93</accession>
    <name>B1KI93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LysE/YggA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2668</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2668"/>
    <dbReference type="EnsemblBacteria" id="ACA86944">
        <property type="protein sequence ID" value="ACA86944"/>
        <property type="gene ID" value="Swoo_2668"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2668"/>
    <dbReference type="eggNOG" id="COG1279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087840_5_1_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="12693" checksum="16A7EFD632E546D8" modified="2008-04-29" version="1" precursor="true">MFSSYIAGFTLGLSLILAIGAQNAFVLKQGLKKHHVFAVCFICALSDAILISFGVAGFGVIVSEFPLIEVISRYAGAVFLLVYGLKSLYSAFKTSHQLDAEGELPASLLKTVLVCLAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB9</accession>
    <name>B1KIB9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325309.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2694"/>
    <dbReference type="EnsemblBacteria" id="ACA86970">
        <property type="protein sequence ID" value="ACA86970"/>
        <property type="gene ID" value="Swoo_2694"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2694"/>
    <dbReference type="eggNOG" id="ENOG50331S5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148693_0_0_6"/>
    <dbReference type="OMA" id="WYKIDGG"/>
    <dbReference type="OrthoDB" id="1829992at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="116" mass="12159" checksum="76D5339A85F0475C" modified="2008-04-29" version="1">MSKLTKEEVISALESALATKQGSAVTIEQKGSWYKIDGGKSLRFSELEAMLAELSGDTPAPKAVEKKAAPAAKPKAAAKKAPVAKKAAPASNKGGKTPKELWREKLAGKGQLPRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP0</accession>
    <name>B1KIP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326863.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4280"/>
    <dbReference type="EnsemblBacteria" id="ACA88536">
        <property type="protein sequence ID" value="ACA88536"/>
        <property type="gene ID" value="Swoo_4280"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4280"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_91_4_6"/>
    <dbReference type="OMA" id="SVQFRYC"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="394"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="536"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="796" mass="88411" checksum="AA50983B309CD8DA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP7</accession>
    <name>B1KIP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4288</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326870.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88543">
        <property type="protein sequence ID" value="ACA88543"/>
        <property type="gene ID" value="Swoo_4288"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4288"/>
    <dbReference type="eggNOG" id="COG0659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_13_1_6"/>
    <dbReference type="OMA" id="TGPMSVT"/>
    <dbReference type="OrthoDB" id="751256at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="442"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="554" mass="58965" checksum="8C5D389D1CD91B80" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ63</accession>
    <name>B1KJ63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325419.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87083">
        <property type="protein sequence ID" value="ACA87083"/>
        <property type="gene ID" value="Swoo_2808"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2808"/>
    <dbReference type="eggNOG" id="ENOG5033EY0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153204_1_1_6"/>
    <dbReference type="OMA" id="HRCYLAI"/>
    <dbReference type="OrthoDB" id="2011411at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021482">
        <property type="entry name" value="DUF3135"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11333">
        <property type="entry name" value="DUF3135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="104" mass="12279" checksum="86426186202DC984" modified="2008-04-29" version="1">MTQLPNFDSLKWLAENNPEELERLQKKLCKEAIDHCPESNKEQLISMHFHLEQQMSRCSNPFHRCYLAISIMNDKFIALNDIINNPQEFREQNAKVLTLPPKKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA5</accession>
    <name>RAPA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase-associated protein RapA</fullName>
            <ecNumber evidence="1">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP-dependent helicase HepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rapA</name>
        <name type="ordered locus">Swoo_4324</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family. RapA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326903.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJA5"/>
    <dbReference type="SMR" id="B1KJA5"/>
    <dbReference type="STRING" id="392500.Swoo_4324"/>
    <dbReference type="PRIDE" id="B1KJA5"/>
    <dbReference type="EnsemblBacteria" id="ACA88577">
        <property type="protein sequence ID" value="ACA88577"/>
        <property type="gene ID" value="Swoo_4324"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4324"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011520_0_0_6"/>
    <dbReference type="OMA" id="MSILERD"/>
    <dbReference type="OrthoDB" id="291634at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016817">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01821">
        <property type="entry name" value="Helicase_RapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023949">
        <property type="entry name" value="Helicase_RapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022737">
        <property type="entry name" value="RapA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040765">
        <property type="entry name" value="Tudor_1_RapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040766">
        <property type="entry name" value="Tudor_2_RapA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12137">
        <property type="entry name" value="RapA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18339">
        <property type="entry name" value="Tudor_1_RapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18337">
        <property type="entry name" value="Tudor_RapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000188192" description="RNA polymerase-associated protein RapA">
        <location>
            <begin position="1"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="163"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="491"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEAH box">
        <location>
            <begin position="278"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="176"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01821"/>
        </source>
    </evidence>
    <sequence length="968" mass="108948" checksum="399BD68A087B4F62" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJB0</accession>
    <name>B1KJB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326908.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4329"/>
    <dbReference type="EnsemblBacteria" id="ACA88582">
        <property type="protein sequence ID" value="ACA88582"/>
        <property type="gene ID" value="Swoo_4329"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4329"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_4_6"/>
    <dbReference type="OMA" id="SWENRPY"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="186"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="320" mass="37132" checksum="516E5EF9B597ECF4" modified="2008-04-29" version="1">MSHDQSAMNELHWLIDMVQTIEVGLVVLDKNFNIQLWNGFMENHSGVSPNSIKDKNLFEQFDDLPSTWLKQKMESVFLLKNRAFISWEQRPYIFKFKNYRPITGRADFMYQNVTLLPLSSLTGQITHISMIVYDVTDVAINRLQLKGANERLEYLSQTDGLTQLHNRRHWQQCMQREFDRHARYGDETSLVMFDIDDFKKVNDNYGHTIGDKVIQHISHLLKQSLRETDCAGRYGGEEFSVVLAKTSATDALQFAERLRKKIEETALVYEDQTINVTVSIGICDIQDELENSGQWLNCADEALYTAKDTGRNKCVIYKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR4</accession>
    <name>B1KJR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324083.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1445"/>
    <dbReference type="EnsemblBacteria" id="ACA85737">
        <property type="protein sequence ID" value="ACA85737"/>
        <property type="gene ID" value="Swoo_1445"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1445"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_11_2_6"/>
    <dbReference type="OMA" id="NPGHINI"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="363" mass="39057" checksum="95ECCF7B431DABAA" modified="2008-04-29" version="1">MTEREHQILAILKQNPLIAQQDLADRLGISRSAVAGHIMNLTHKGIIRGKGYILAESRYAVVVGGANMDILGRPLDTLQVGDSNPGSVTCSPGGVGRNIAENLARLGSQTRLLSAVGKDTYGQAIIDQCQQAGIDMQACLQLKDASTSTYLSVLDGDSDMHVAINDMAILDRLSVELLKAQEEMLRRADLLILDANLSAPALEYLLSNFSDRPIFVDTVSCAKAKKIQPFLSAIHTLKPNLKEAEQLSGISIANYGELPKLGHWFHEQGVQRIFLSLGADGVFYSDGQTQALIPAVDVPMVNANGAGDAFLAGLAHGWLQDWDIEQSTKFAMAAAVVALSHLATINPNMSEMSVNRVIKESIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK31</accession>
    <name>B1KK31_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylation site containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326988.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4410"/>
    <dbReference type="EnsemblBacteria" id="ACA88662">
        <property type="protein sequence ID" value="ACA88662"/>
        <property type="gene ID" value="Swoo_4410"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4410"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098637_3_0_6"/>
    <dbReference type="OMA" id="GVATIWQ"/>
    <dbReference type="OrthoDB" id="1986406at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="18037" checksum="85621407DEA5C038" modified="2008-04-29" version="1" precursor="true">MNKQNGFTLIELVVVIIILGILAVTAAPKFINLQSDARASTVDGVKAALQGANTLIYSKAAIAGKEADAGASITVATGVVVTTDYGNINSSVTVATVKSNLENAMDMTFEALSDGTADIATEDWAVWSSATTGFVIVPKGKKADDACRLNYTVATKNTTTGVITPAQISTTTTDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK40</accession>
    <name>B1KK40_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA biogenesis protein MshJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326997.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4419"/>
    <dbReference type="EnsemblBacteria" id="ACA88671">
        <property type="protein sequence ID" value="ACA88671"/>
        <property type="gene ID" value="Swoo_4419"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4419"/>
    <dbReference type="eggNOG" id="COG3167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102941_0_0_6"/>
    <dbReference type="OMA" id="MDPNQDY"/>
    <dbReference type="OrthoDB" id="2020115at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="218" mass="24876" checksum="33971A79767BDBBD" modified="2008-04-29" version="1" precursor="true">MKQKLEEVAARFDLLSQRERVMVASAALIVIGLLCYMPLESLLLKQSKLTQQNKGISAENQVSMQQIALYNQRLAQDPNDEYSARFATLEQQSTELDKQLSFQMVDMVPADHMPALLSQLLEKVRGIKLQNFQSIAPTPLLAVGEEKKMNLYSHGLRLTFQGDYFAVLKFVEAIEAMPNKLYWKRMEYQVDEYPMADVVLELYTLSINKDFISVSSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK72</accession>
    <name>B1KK72_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polysulphide reductase NrfD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4451</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NrfD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327029.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4451"/>
    <dbReference type="EnsemblBacteria" id="ACA88703">
        <property type="protein sequence ID" value="ACA88703"/>
        <property type="gene ID" value="Swoo_4451"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4451"/>
    <dbReference type="eggNOG" id="COG3301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045348_1_2_6"/>
    <dbReference type="OMA" id="ILHGAEW"/>
    <dbReference type="OrthoDB" id="1903395at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005614">
        <property type="entry name" value="NrfD_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03916">
        <property type="entry name" value="NrfD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="315" mass="34032" checksum="440DE6BD1EF5707F" modified="2008-04-29" version="1">MDGNIEFTMGLSDGLAWPWPIAVYLFFAGISGGALATALFLRFYKKQTTNTPFYKAAALISFVTISLGMLCLVLDLTNPLFFWRILVYYNLNSVMSIGVIALSVYIPLVAVIALFALEEEIRSIPALKALVPVIEKLKGIRRPCEVSVLVLALAVCAYTGFLISALVRFPIINTSVLPALFIASGISAGAAAAKMLAVSVFKEDLHSQDMKILHGAEWPIMIAEMLFIFMIVTSLMTGNAGAQSAFNAFHTGQWAAVFWFGVVGLGFGGPLLLNFATGKTFSHSAKAFYLSGVCAVAGMMCLRMFILYAGQLYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKB1</accession>
    <name>B1KKB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324097.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1463"/>
    <dbReference type="EnsemblBacteria" id="ACA85751">
        <property type="protein sequence ID" value="ACA85751"/>
        <property type="gene ID" value="Swoo_1463"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1463"/>
    <dbReference type="HOGENOM" id="CLU_2144129_0_0_6"/>
    <dbReference type="OrthoDB" id="1857061at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766753" evidence="1">
        <location>
            <begin position="23"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12304" checksum="436ED9536E524DC7" modified="2008-04-29" version="1" precursor="true">MKLIILACFLVLSVTFSTSANAAFHCSADINRILIYGSGTVNIRHSGRNDFTVICDLNNEWKGVSVTTCAMWTAMLQNIKKNNGKAIFYYGGEGTCAALPTYGSTPAPVYIGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC9</accession>
    <name>B1KKC9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF637 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324115.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1481"/>
    <dbReference type="EnsemblBacteria" id="ACA85769">
        <property type="protein sequence ID" value="ACA85769"/>
        <property type="gene ID" value="Swoo_1481"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1481"/>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_263573_0_0_6"/>
    <dbReference type="OMA" id="WLEANIS"/>
    <dbReference type="OrthoDB" id="791688at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043170">
        <property type="term" value="P:macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006915">
        <property type="entry name" value="DUF637_hemagglutn_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025157">
        <property type="entry name" value="Hemagglutinin_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04830">
        <property type="entry name" value="DUF637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13332">
        <property type="entry name" value="Fil_haemagg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF637" evidence="2">
        <location>
            <begin position="659"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1067"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1275" mass="137409" checksum="5E49671C185F9DF7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKJ2</accession>
    <name>ISPG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
            <ecNumber evidence="1">1.17.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ispG</name>
        <name type="ordered locus">Swoo_1544</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IspG family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324178.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKJ2"/>
    <dbReference type="SMR" id="B1KKJ2"/>
    <dbReference type="STRING" id="392500.Swoo_1544"/>
    <dbReference type="PRIDE" id="B1KKJ2"/>
    <dbReference type="EnsemblBacteria" id="ACA85832">
        <property type="protein sequence ID" value="ACA85832"/>
        <property type="gene ID" value="Swoo_1544"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1544"/>
    <dbReference type="eggNOG" id="COG0821">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042258_0_0_6"/>
    <dbReference type="OMA" id="PTCGRTQ"/>
    <dbReference type="OrthoDB" id="665306at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000097186" description="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)">
        <location>
            <begin position="1"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <sequence length="371" mass="40514" checksum="0819A8D20AB3CFFE" modified="2008-04-29" version="1">MYNENPIKRRASTRIYVGDVPIGDGAPIAVQSMTNTLTTDVDATVAQIRALENVGADIVRVSVPTMDAAEAFKLIKQQTNIPLIADIHFDYRIALKVAEYGVDCLRINPGNIGNESRIKSVVECARDKNIPIRIGINGGSLEKDLMDKYKEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVEAYRLLAKQIVQPLHLGITEAGGLRSGSVKSSVGLGMLLAEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVINTVNELERRLEDVITPMDVSIIGCVVNGPGEALVSDIGLTGGNRKSGYFDDGVRQKERFDNDNIVDSLEAKIRAKASIINGRIPVQDLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL1</accession>
    <name>B1KKL1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325564.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2955"/>
    <dbReference type="ESTHER" id="shewm-b1kkl1">
        <property type="family name" value="Proline_iminopeptidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87228">
        <property type="protein sequence ID" value="ACA87228"/>
        <property type="gene ID" value="Swoo_2955"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2955"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024518_2_0_6"/>
    <dbReference type="OMA" id="TNEYEHN"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="52"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="431" mass="49067" checksum="AA33A223BB065CA6" modified="2008-04-29" version="1">MKPELSLAGLSARKHTFTLPLNYDDPQGKKIQVFARELLSNDIDTDSNERPFLVFFQGGPGFSAVRPADNSGWIKRALTEFRVLLLDQRGTGLSTPVSYLSLAHFNSELQAEYLSHFRADNIIRDAEAIREQLCPGQKWSILGQSFGGFCVLKYLNDAPEGVKEAYITGGIPSLTRSADEVYQATYQRVLAKNRDFFTRFSDAQELVTQIAEHLTHHEVRIATGERLTVEMLQLLGINIGMEQGPESVYYLLEHALIETDLGTHVNPLFLAHFCHLLDFNTNPIFALLHESIYCQRSASNWSAQRVRAQYDEFNYEFGKPFLFTGEMVYPWFFEQFTNLKPLKHAANLLATNSDWPTLYNLDTLANNQVPVAAAIYSEDMFVEMSYSLETAKQVGNLKYWLTSEYEHNGIRMDGEHILDKLIALNRGEQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN6</accession>
    <name>B1KKN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sporulation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325589.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2982"/>
    <dbReference type="EnsemblBacteria" id="ACA87253">
        <property type="protein sequence ID" value="ACA87253"/>
        <property type="gene ID" value="Swoo_2982"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2982"/>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068683_1_1_6"/>
    <dbReference type="OMA" id="RGYQAHT"/>
    <dbReference type="OrthoDB" id="1648036at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="2">
        <location>
            <begin position="117"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="21908" checksum="E3FDB614C431F9C4" modified="2008-04-29" version="1">MSSHFQNRLVGVIVLVALGVIFLPDILDGKKEHQAEQFAEIPLRPEVEALELPDQEFKTVDLSEKEQAFEPAADELDQLVQEIEEKEALAQQPSTEVANKAVVESKPVEVATTQPNKPAASAYTLQLGSFKNASNVNGLVKQLREKGFTAYTLPEKPVDGQLTKVFVGPNVSKAKLQAQSADIKKITKLSGRIVSYVPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKU9</accession>
    <name>B1KKU9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327081.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4504"/>
    <dbReference type="EnsemblBacteria" id="ACA88755">
        <property type="protein sequence ID" value="ACA88755"/>
        <property type="gene ID" value="Swoo_4504"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4504"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_19_3_6"/>
    <dbReference type="OMA" id="IFRCEFA"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="15412" checksum="F904F141686537AC" modified="2008-04-29" version="1">MAFDDKFRLSSHAVIFDRDNRVLLLKATYGDKHWGLPGGALDVGETIHEALLRECREELGCEVKVNYLSGVYYHKAYDSQAFIFRCELEDISLITLSDEHSEFKFEAVENLSAVQQRRVRQCLAFDGQVMSDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL26</accession>
    <name>B1KL26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322716.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0066"/>
    <dbReference type="EnsemblBacteria" id="ACA84367">
        <property type="protein sequence ID" value="ACA84367"/>
        <property type="gene ID" value="Swoo_0066"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0066"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091262_0_0_6"/>
    <dbReference type="OMA" id="YHYPAKD"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025722">
        <property type="entry name" value="TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13972">
        <property type="entry name" value="TetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="215" mass="25122" checksum="993769455CC5EFD2" modified="2008-04-29" version="1">MKTRDKIIYASLELFNEKGERNITTNHIAAHLGISPGNLYYHFRNKEDIIRSIFSLYQAHLETSFQPYEGEPATIDLLIGYFDAMFYAMWEFRFMYANLTDILNRDEELKSLYLVTQQQVLTRCSHVLSKLNQDGVIAIDEEEIPHLAETIRMIVCFWIGYKQTHSSQMEITKSSLYEGLLRILMISKAYSTSESRTTFVRLEQHYRELAAAPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL82</accession>
    <name>B1KL82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322772.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0122"/>
    <dbReference type="EnsemblBacteria" id="ACA84423">
        <property type="protein sequence ID" value="ACA84423"/>
        <property type="gene ID" value="Swoo_0122"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0122"/>
    <dbReference type="eggNOG" id="ENOG5032FZN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129879_0_0_6"/>
    <dbReference type="OMA" id="NDPSCRW"/>
    <dbReference type="OrthoDB" id="1846103at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="19028" checksum="BBDDAA0A91D15B42" modified="2008-04-29" version="1" precursor="true">MSLSHTPRLNAATHLPLLLTILFLSLIPPSHASNSKPLPLGSVLDSQGNPIQLPSKQESALEIPSIKPTKEYQSTPAKSRKRSQSRSKKSKLSRKQQLASRTSVANDPGCRWLDARMDHLERKLNDKGNSNANSYHKKELSIREQEWKCLKCGAEGPKQTDHDHCQYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL94</accession>
    <name>B1KL94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AbgT putative transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322784.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84435">
        <property type="protein sequence ID" value="ACA84435"/>
        <property type="gene ID" value="Swoo_0134"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0134"/>
    <dbReference type="eggNOG" id="COG2978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040132_0_0_6"/>
    <dbReference type="OMA" id="MLPYSIC"/>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015558">
        <property type="term" value="F:secondary active p-aminobenzoyl-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902604">
        <property type="term" value="P:p-aminobenzoyl-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004697">
        <property type="entry name" value="AbgT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30282">
        <property type="entry name" value="PTHR30282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03806">
        <property type="entry name" value="ABG_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="498"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="538" mass="56998" checksum="C544E28AF0BC89BB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL95</accession>
    <name>B1KL95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322785.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0135"/>
    <dbReference type="EnsemblBacteria" id="ACA84436">
        <property type="protein sequence ID" value="ACA84436"/>
        <property type="gene ID" value="Swoo_0135"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0135"/>
    <dbReference type="eggNOG" id="COG2169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_692415_0_0_6"/>
    <dbReference type="OMA" id="FTWMISS"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="287"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="391" mass="44941" checksum="504581911EC71D74" modified="2008-04-29" version="1" precursor="true">MQLMTILLLISVGMSFFMMGYAATTPHQNAKARLCFSLMLVGLISLMIELAIFEEGGSFLYIISISGPLSVSVPIFFYLYFKASVGLSDEFQWRNARHLVIPFIYLAIMMPYNLLDEVGKSHFFSQVYAKEVISWPLSMTPIRFSRLLIISSLGLFYLYLSWRELHIELNNKKQDVLREMNKLKGAFLGISLSFIVIFLFFLFRLPHQFTWMISSILLVITAISCMIFYYLPVLGKKLISDADLHQLLPPKAQELQQEVGQTSPEADTPDRQYRSSVTNDLAKEVIHHLNILMEGGIYKDSTLSLGKLASQLKLSTHHLSQIINQQTQGNYFDLINQYRIKDAQHLLINTNMSIIDIAYEVGYNSKSSFYTEFKRRTQMTPNQFKKSNKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI9</accession>
    <name>B1KLI9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Flagellar biosynthetic protein FliP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">fliP</name>
        <name evidence="15" type="ordered locus">Swoo_1628</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Plays a role in the flagellum-specific transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324260.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1628"/>
    <dbReference type="EnsemblBacteria" id="ACA85914">
        <property type="protein sequence ID" value="ACA85914"/>
        <property type="gene ID" value="Swoo_1628"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1628"/>
    <dbReference type="eggNOG" id="COG1338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042028_0_1_6"/>
    <dbReference type="OMA" id="IMITCFP"/>
    <dbReference type="OrthoDB" id="1049349at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005837">
        <property type="entry name" value="FliP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587:SF0">
        <property type="entry name" value="PTHR30587:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00951">
        <property type="entry name" value="FLGBIOSNFLIP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01103">
        <property type="entry name" value="fliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01060">
        <property type="entry name" value="FLIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8 13" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="12 13" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="6 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="15" id="KW-0969">Cilium</keyword>
    <keyword evidence="15" id="KW-0282">Flagellum</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 13" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767462" description="Flagellar biosynthetic protein FliP" evidence="14">
        <location>
            <begin position="22"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA85914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="27488" checksum="08A8E8CF8E8818B2" modified="2008-04-29" version="1" precursor="true">MNRLLLLITFTLLLFSPDIFAQDGILPAVTVSTGADGDTQYSVTMQILLLMTALSFLPAMLIMLTSFTRIIIVLSILRQAIGLQQTPSNQVLIGMSMFLTFFIMSPVFDKVYDSAVKPYMNESMNIEQAFHVGKEPIKEFMLAQTRVTDLETFVEISGYQNINSVDEAPMSVIIPAFITSELKTAFQIGFMLFVPFLVLDLVVASILMAMGMMMLSPMIVSLPFKIMLFVLVDGWSLVMGTLANSFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLJ3</accession>
    <name>B1KLJ3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flagellar biosynthesis protein FlhA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flhA</name>
        <name evidence="8" type="ordered locus">Swoo_1632</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324264.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1632"/>
    <dbReference type="EnsemblBacteria" id="ACA85918">
        <property type="protein sequence ID" value="ACA85918"/>
        <property type="gene ID" value="Swoo_1632"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1632"/>
    <dbReference type="eggNOG" id="COG1298">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015346_3_0_6"/>
    <dbReference type="OMA" id="MAINPGQ"/>
    <dbReference type="OrthoDB" id="436367at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025505">
        <property type="entry name" value="FHIPEP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006301">
        <property type="entry name" value="FlhA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01398">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00994">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="699" mass="75291" checksum="6196BF74578FE801" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP0</accession>
    <name>B1KLP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325673.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3066"/>
    <dbReference type="EnsemblBacteria" id="ACA87337">
        <property type="protein sequence ID" value="ACA87337"/>
        <property type="gene ID" value="Swoo_3066"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3066"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_37_0_6"/>
    <dbReference type="OMA" id="EPPWPAD"/>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="33843" checksum="CA639268CF33C29C" modified="2008-04-29" version="1">MHTEFPPLNALLAFESASRHLSFSHAADELFVTHGAISKQIKSLESYLGTPLFLRQHRKLALTDDAKRYLPQIQAALQTIKTATDEIKSHQMQSQTLAINVLPSLTINWLIPRMEEFKQRYPHLYVDLSIGDFTVNFEQSRCDIAIRSATQAPKEVNYLKLMDEDLCLVCAPLLMKELHSLDDINKMTLLKHTTRPELWPYWADKVGLTLTTEKKFGMEHFYMLSQAAVSGMGLALIPRFFIEKELADGSLVIPFDEGFTSPYTYYVITPKSQNLPLKAQAFIDWLLEIFAPYRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ7</accession>
    <name>B1KLQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3083</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325690.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3083"/>
    <dbReference type="EnsemblBacteria" id="ACA87354">
        <property type="protein sequence ID" value="ACA87354"/>
        <property type="gene ID" value="Swoo_3083"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3083"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_0_6"/>
    <dbReference type="OMA" id="DCAGYYG"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767192" evidence="6">
        <location>
            <begin position="33"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="56"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="341"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="912" mass="97956" checksum="9E026ACA1A4400EA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV3</accession>
    <name>B1KLV3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase</fullName>
            <ecNumber evidence="3">3.1.7.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4583</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14253"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:77828"/>
            <dbReference type="EC" id="3.1.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; ppGpp biosynthesis; ppGpp from GDP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EC" id="3.1.7.2" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327158.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4583"/>
    <dbReference type="EnsemblBacteria" id="ACA88833">
        <property type="protein sequence ID" value="ACA88833"/>
        <property type="gene ID" value="Swoo_4583"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4583"/>
    <dbReference type="eggNOG" id="COG0317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012300_3_0_6"/>
    <dbReference type="OMA" id="DWISSPK"/>
    <dbReference type="OrthoDB" id="204079at2"/>
    <dbReference type="UniPathway" id="UPA00908">
        <property type="reaction ID" value="UER00886"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008893">
        <property type="term" value="F:guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015970">
        <property type="term" value="P:guanosine tetraphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="6">
        <location>
            <begin position="45"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="7">
        <location>
            <begin position="388"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="5">
        <location>
            <begin position="630"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="703" mass="79280" checksum="D481E598FA3C687B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLX7</accession>
    <name>B1KLX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327182.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4607"/>
    <dbReference type="EnsemblBacteria" id="ACA88857">
        <property type="protein sequence ID" value="ACA88857"/>
        <property type="gene ID" value="Swoo_4607"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4607"/>
    <dbReference type="HOGENOM" id="CLU_2587797_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="80" mass="8618" checksum="BC45DCB48E00851E" modified="2008-04-29" version="1" precursor="true">MNGIDKGQKNSKSHGLIMLALLLVLSLSACSQMLMRQTCASLAITKSDCLAPLPISNKPETVESLANKNTKENKDTESEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM61</accession>
    <name>B1KM61_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322823.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0173"/>
    <dbReference type="EnsemblBacteria" id="ACA84474">
        <property type="protein sequence ID" value="ACA84474"/>
        <property type="gene ID" value="Swoo_0173"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0173"/>
    <dbReference type="eggNOG" id="COG3346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047737_2_2_6"/>
    <dbReference type="OMA" id="NRGWLPW"/>
    <dbReference type="OrthoDB" id="1908280at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="231" mass="26010" checksum="23BB57E3C74CC5EC" modified="2008-04-29" version="1">MLVILATVSLFLLLVKLGFWQLSRAELKEELQSQLTSRQAAAPLSYRKLLSLPASEPLTGYKLSTTVTPVGNKVFLLDNQIFNGQVGYLALQVMQVNPIDPWLLVELGFVPAGNDRRVLPKLPHINQSQTFTGRLYQKQANPMSSDLFAEEGWPKRVQNLNISQIETTLNHPVALAVLQPESIKGINLPHPWQPIPLSAQKHLGYALQWFSMAVAFALLVFYFIRVRLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME7</accession>
    <name>B1KME7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Virulence factor MVIN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1659</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1659"/>
    <dbReference type="EnsemblBacteria" id="ACA85945">
        <property type="protein sequence ID" value="ACA85945"/>
        <property type="gene ID" value="Swoo_1659"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1659"/>
    <dbReference type="eggNOG" id="COG0728">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_569716_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="479" mass="54765" checksum="F474F8B577BC5038" modified="2008-04-29" version="1">MVSIALFALILGGKASGLLKDVLITYSFGVSKETDAFFLATYISTLIYIGLYSSISIVIIPKCKDVLNRKSSAIELYSLYLMYLSLSIFISFVTYFFSDEIVALVANNEHVMRKSVDYLKLMALTFPLSTAVGILNSLQLCKNKPLLTYVTPVVNNFAFCVTIYLVDSGDFNLLLYVAIVGWFVLLLFNFFEQKVRFRKVINRFLLIRKKSLKPTAIGLVVLFVVVEQLTNFIPVYFVSMGSAGELSEFTYANKLNLFILSISLLLITSHVLPNLSSKKNLLEIRMVLYKSFDYLSYFLLPLVIVAAINSKEIVELIFFRGSFSIENVINVTKIFTLMVLILPAFIFKDILNRVYFVVKKDTECLTITLVTAIVSLVVNSFTYPFFGAISVVFNFVIITYIQVVVLFFFLFKFRLWFSLATFKAFIFRIVNILFVSYCLSYFDFGLVLYSSLFLLFYISISYLFRDELLLNSLKKLRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME9</accession>
    <name>B1KME9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="5 7">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="5 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324293.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1661"/>
    <dbReference type="EnsemblBacteria" id="ACA85947">
        <property type="protein sequence ID" value="ACA85947"/>
        <property type="gene ID" value="Swoo_1661"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1661"/>
    <dbReference type="eggNOG" id="COG1091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045518_2_2_6"/>
    <dbReference type="OMA" id="FRHKGFP"/>
    <dbReference type="OrthoDB" id="1076083at2"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="UniPathway" id="UPA00281"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009243">
        <property type="term" value="P:O antigen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="8">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="32372" checksum="D79BE849DB12C4C3" modified="2008-04-29" version="1">MRILVVGATGMLGYSLFSNLNEHAHLSVFGTVRSIVGKEAFFSNVQQQLVTGVDAYDIVSLQHAIETVAPDVVINCVGLIKQHGISKQHIDAVKINALLPHELANICDRFDARLIHFSTDCVFTGDIGFYSEESLPDARDLYGKSKCLGEVNYGKHLTLRTSIIGHELTSAVSLVDWFLSQGESTRGFSKAVFSGLPTCYIAKLLADCILINPEIVGLFHLSVDPIDKHTLLELIAEQYQKQITITDSQELVIDRSLNSDKFRQLTQFSPPEWSELVGYMYKDYVRRYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI3</accession>
    <name>B1KMI3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324327.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1696"/>
    <dbReference type="EnsemblBacteria" id="ACA85981">
        <property type="protein sequence ID" value="ACA85981"/>
        <property type="gene ID" value="Swoo_1696"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1696"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026911_7_0_6"/>
    <dbReference type="OMA" id="HRYHNPL"/>
    <dbReference type="OrthoDB" id="564091at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="50120" checksum="CA7DD20596D21484" modified="2008-04-29" version="1">MSQVLKQQTDLTTMQAKSRFSKSLFWLGSAQVMGRVVRLASSIILARIFTPEVFGQVAIILTCFELICTPTRRITSASLIKMNDDELAASLPNANKINWFASITAFVAMSLLSWPLAFYHQDTIIIAPMILMATSYLLLPIGMLHAAINLRANKMRVVGRAILWQTVGDGLLTATFALLGLGIWAIILPKVLVILIWIAIHRYHNPLPKSNDHSVSGLPIPKMFNFGSMVGLSDLSISLRQNIDYLLIGYFLGLEALGIYFFAFNTSLGISLGIIQSYGTALYSHLCGAKKDQQKIIASQELKARYSHSLILILKIAIPVITLQTLLSPIYLPLIYGSKWIEAGALPVFILLCLSGLVRPIGEAASQLLISLNKSRLNLSFNLGFTLLLAITIAVCSQWGLVAVALGILIIHLICMPALSFYIQLFILNKQAICTEEEQKSHSKRFNQEVHHDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KML7</accession>
    <name>B1KML7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Decaheme cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3124</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325731.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3124"/>
    <dbReference type="EnsemblBacteria" id="ACA87395">
        <property type="protein sequence ID" value="ACA87395"/>
        <property type="gene ID" value="Swoo_3124"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3124"/>
    <dbReference type="eggNOG" id="ENOG502ZBEP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011293_0_0_6"/>
    <dbReference type="OMA" id="HAEGHYL"/>
    <dbReference type="OrthoDB" id="864595at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020014">
        <property type="entry name" value="Decahaem_cyt-c_OmcA/MtrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03507">
        <property type="entry name" value="decahem_SO1788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="4">
        <location>
            <begin position="340"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="741" mass="79937" checksum="7884A7AC86128C2B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN6</accession>
    <name>B1KMN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription activator effector binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325750.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3143"/>
    <dbReference type="EnsemblBacteria" id="ACA87414">
        <property type="protein sequence ID" value="ACA87414"/>
        <property type="gene ID" value="Swoo_3143"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3143"/>
    <dbReference type="eggNOG" id="COG3708">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106591_0_1_6"/>
    <dbReference type="OMA" id="MMHHIPN"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029441">
        <property type="entry name" value="Cass2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14526">
        <property type="entry name" value="Cass2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_E_bind" evidence="1">
        <location>
            <begin position="10"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="165" mass="19047" checksum="D53251ECFFD93430" modified="2008-04-29" version="1">MSQFKEEPCMPVLVTQEAIGVKGMFVRTSNRAEQDVNTQKIAPLWQGFMQRSDVQSNTSSPIYGCYFDYESDVNGEFNVLLGLMKEQVEPINSELTKLNLEAGEYLRFRAKGEMPEVVIKLWGEVWQYFNDENCSYSRRYLTDYECYTATDGVDIYIGVNRKLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMS6</accession>
    <name>B1KMS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exporter of the RND superfamily protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325790.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3183"/>
    <dbReference type="EnsemblBacteria" id="ACA87454">
        <property type="protein sequence ID" value="ACA87454"/>
        <property type="gene ID" value="Swoo_3183"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3183"/>
    <dbReference type="eggNOG" id="COG1033">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008861_1_0_6"/>
    <dbReference type="OMA" id="HLYFGWR"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="564"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="687"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="222"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="554"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="717" mass="79392" checksum="9882C3A7E91A745E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMW6</accession>
    <name>B1KMW6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsE</name>
        <name evidence="12" type="ordered locus">Swoo_4673</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="8">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327246.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4673"/>
    <dbReference type="EnsemblBacteria" id="ACA88923">
        <property type="protein sequence ID" value="ACA88923"/>
        <property type="gene ID" value="Swoo_4673"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4673"/>
    <dbReference type="eggNOG" id="COG0098">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065898_2_2_6"/>
    <dbReference type="OMA" id="KRGCGSW"/>
    <dbReference type="OrthoDB" id="1505038at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="13"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="168" mass="17871" checksum="856FC0A91B77FDE4" modified="2008-04-29" version="1">MAKFEAQQQKDDLQEKLVAVNRVSKVVKGGRIFSFTALTVVGDGNGKVGFGYGKAREVPAAIQKAMEKARRNIVSVELNNGTLHHPVKGRHTGSRVYMQPASDGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALVHMKSPSQIAAKRGLNVDEIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN52</accession>
    <name>B1KN52_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322898.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0248"/>
    <dbReference type="EnsemblBacteria" id="ACA84549">
        <property type="protein sequence ID" value="ACA84549"/>
        <property type="gene ID" value="Swoo_0248"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0248"/>
    <dbReference type="eggNOG" id="ENOG5032TBM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1170021_0_0_6"/>
    <dbReference type="OMA" id="FFRNQFV"/>
    <dbReference type="OrthoDB" id="1164620at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="25882" checksum="401E03B0355A4B8E" modified="2008-04-29" version="1">MPLSAIFTEAYNFFRNHISQLAALTVPILFVQVGIQLWLGMEMANADMENPQFGGIHMAAVMALLLVFSLLIASLTIFLEIRSQGHEANTALILKTSLSFVPGLLLAGVFSGLAILAPVMLFAAFGPLWLVGLTMSIYIFARLAYVNFMVVVERLTPLEAIKGSFKFSGPIAFKTLMVLMLYIPISLIGGSLSSLAQSVGFPLQLVVEVFVAFIGLFVNVALFRLYMVSRPNVEEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN78</accession>
    <name>B1KN78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322924.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0274"/>
    <dbReference type="EnsemblBacteria" id="ACA84575">
        <property type="protein sequence ID" value="ACA84575"/>
        <property type="gene ID" value="Swoo_0274"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0274"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_0_6"/>
    <dbReference type="OMA" id="FTRQGQH"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="34379" checksum="FAF424B8DB9866DA" modified="2008-04-29" version="1">MELEDIYRQDLSLLIALQILVEECSVTQAAKRLHLSQSATSRILSRLREMLGDPLFSRVGQKLVPTQFALDCYQQLQQPTGQLIEMLSPKAFVPNECQQHFTLAATDYAMQALIPFILPDIYNKAPNIKLEIIPVQHRELQSQLSVQGADMAICRAIGQTQQLNQTFLGRVGVSCLLSAEHPLAHQALTLEDYLHFPHATIAISDGVKALLDAAIASYPPRDELLRTPHLDSALALLQFHPAIITLPAGIAELAALKHRLRVKPLPFDIPPLDYNLFWHSRAELDKAQQWLREEISNSIRRLLKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE8</accession>
    <name>B1KNE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Conserved carboxylase region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324371.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1740"/>
    <dbReference type="EnsemblBacteria" id="ACA86025">
        <property type="protein sequence ID" value="ACA86025"/>
        <property type="gene ID" value="Swoo_1740"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1740"/>
    <dbReference type="eggNOG" id="COG0511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5016">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_4_3_6"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="519"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="596" mass="64959" checksum="62303A8F38BD8E4A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNJ7</accession>
    <name>B1KNJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1790"/>
    <dbReference type="EnsemblBacteria" id="ACA86074">
        <property type="protein sequence ID" value="ACA86074"/>
        <property type="gene ID" value="Swoo_1790"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1790"/>
    <dbReference type="eggNOG" id="ENOG5031H60">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_216513_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="39" mass="4463" checksum="66546A5F334F6D78" modified="2008-04-29" version="1">MSQPFKDAFNIFYFIGFILVLLIPTLPATLSWLKFSGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL9</accession>
    <name>B1KNL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324442.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1812"/>
    <dbReference type="EnsemblBacteria" id="ACA86096">
        <property type="protein sequence ID" value="ACA86096"/>
        <property type="gene ID" value="Swoo_1812"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1812"/>
    <dbReference type="eggNOG" id="ENOG5032S61">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116211_0_0_6"/>
    <dbReference type="OMA" id="QEYFTVH"/>
    <dbReference type="OrthoDB" id="1923832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="197" mass="22076" checksum="18FF922DC5A2D9AF" modified="2008-04-29" version="1">MITDSSPYFSVKHDFKVYLTAWPDNAPIPTEGELTLMLPLGLQLISDVKSLEADCLLQLRHLDDEAKTVVEYLKLQSKKVDLVLQHVLEREAHDGELHQGKFFGGSGIRIIGATQFDVGKQFKLTLHIKEELVALLCFAQVTATQVIEATDVEPQTGYLTELEFSVITDTDVEQLVKASLSVQQRQLKQRKLAKKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP1</accession>
    <name>B1KNP1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacid CoA-transferase, B subunit</fullName>
            <ecNumber evidence="3">2.8.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit B family.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.5" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325835.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3229"/>
    <dbReference type="EnsemblBacteria" id="ACA87499">
        <property type="protein sequence ID" value="ACA87499"/>
        <property type="gene ID" value="Swoo_3229"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3229"/>
    <dbReference type="eggNOG" id="COG2057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019942_4_1_6"/>
    <dbReference type="OMA" id="VAMMHTN"/>
    <dbReference type="OrthoDB" id="1380130at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008260">
        <property type="term" value="F:3-oxoacid CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="218" mass="23264" checksum="9FD0436588543A6D" modified="2008-04-29" version="1">MALSREQLAQRVAQELKDGYYVNLGIGIPTLVANYIPDGMDVMLQSENGLLGMGEFPTEETIDADLINAGKQTVTAVDGASFFSSAESFAMIRGGHVDLTVLGAFEVDEQGSIASWMIPGKLIKGMGGAMDLVAGADNIIVTMMHADKRGNSKLLPKCELPLTGFGCIKRVLTDLAFMEIKDGAFHLLERAPGVTVEEIVAKTAGKLIVPDNVPEMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS3</accession>
    <name>B1KNS3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325867.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3261"/>
    <dbReference type="EnsemblBacteria" id="ACA87531">
        <property type="protein sequence ID" value="ACA87531"/>
        <property type="gene ID" value="Swoo_3261"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3261"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050180_2_0_6"/>
    <dbReference type="OMA" id="VPPMERF"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="51"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="250" mass="27335" checksum="761E55D7F9F7FDC2" modified="2008-04-29" version="1">MSHYLVLLLLAPLLALQGIYVRRTSLVLPEAAGERSGSIGKGEKLKVLIAGDSAAAGVGVDKQDRALTGYLTRELAKDHCVTWALIAKSGSNTQDLIKHLSKVKGEKFDVVLLSLGVNDVLTPLSASKWQGQLGRLTQVLHHDFGAKQVWFTSVPPMERFPLLPQPLRWFLGRRAQEFNRVLASYVEQAECCGLVDLSVHLPKQEPDSIKCAKVSAMAADGFHPDESLYQLWGSSAARVIDKQIKLNSVA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY2</accession>
    <name>RIBB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="1">DHBP synthase</shortName>
            <ecNumber evidence="1">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ribB</name>
        <name type="ordered locus">Swoo_4764</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327330.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNY2"/>
    <dbReference type="SMR" id="B1KNY2"/>
    <dbReference type="STRING" id="392500.Swoo_4764"/>
    <dbReference type="EnsemblBacteria" id="ACA89013">
        <property type="protein sequence ID" value="ACA89013"/>
        <property type="gene ID" value="Swoo_4764"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4764"/>
    <dbReference type="eggNOG" id="COG0108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020273_3_0_6"/>
    <dbReference type="OMA" id="DAGGLIC"/>
    <dbReference type="OrthoDB" id="900513at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="chain" id="PRO_1000098291" description="3,4-dihydroxy-2-butanone 4-phosphate synthase">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="37"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="150"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="1">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00180"/>
        </source>
    </evidence>
    <sequence length="217" mass="23440" checksum="7DEB6BE67511737C" modified="2008-04-29" version="1">MNQSLLTPFGTAIERVEAALTSLRQGQGVLVVDDEDRENEGDLIYSAQSLTNEQMALLIRECSGIVCLCLTDERIKQLDLPPMVEDNSSQYGTAFTVSIEAKVGVTTGVSAADRVTTIKAAIADNAVPEDLARPGHVYPLRAQSGGVFSRRGHTEGTIDLMLLAGLKPAGVLCEITNPDGTMARLPEIIQFGQQHNLPVLTIEDIVEYRKVTMEKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP13</accession>
    <name>B1KP13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_4795</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327361.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4795"/>
    <dbReference type="EnsemblBacteria" id="ACA89044">
        <property type="protein sequence ID" value="ACA89044"/>
        <property type="gene ID" value="Swoo_4795"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4795"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_19_6"/>
    <dbReference type="OMA" id="AHPTMKP"/>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="12">
        <location>
            <begin position="307"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="366"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="553"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA89044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="638" mass="69488" checksum="CB66F710BFF4482D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP16</accession>
    <name>B1KP16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327364.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4798"/>
    <dbReference type="EnsemblBacteria" id="ACA89047">
        <property type="protein sequence ID" value="ACA89047"/>
        <property type="gene ID" value="Swoo_4798"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4798"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029518_0_0_6"/>
    <dbReference type="OMA" id="DTFLRDW"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="354"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="485" mass="55629" checksum="9953F2E5BD863CA0" modified="2008-04-29" version="1" precursor="true">MGKAVWSDKKRFIWILSVLLLTAFIFTSGISYKVAHDSLSEQISENTLPLTSDNIYSEIQQDLLQPIFISSLMAQDTFVRDWTINDEEDPQQLIRYLREIQNKYDTVTSFFVSEKSRKYYHSTGVLKKIEDTAPNDAWYFRVRSLPTSESYEVNIDLDTANRTRTVVYVNYKVHDFEGNFIGVTGVGLAVERVQKLIKLYQQRYNRRVYFVDTEGHVTLHGEQYSGSQTLQNSPGLEKYATRILTSPSASFSYVRDNKTVYLNSRMVSDFKWYLMVEQEEAEGEKKILNTFWVNIVLGLMVIVVILVIANLTLGRYQRKLEVMASTDKLTGATNRQMFEEYFSHSLQNAEISATPVSVILLDIDYFKSVNDNFGHSIGDLVIKTVANIIRRQLRSEDIVCRWGGEEFLLLLPNIDLSHAADMAERIRESIAERKISVNEHEIGITVSSGVAQYKLGEPRADLINRVDVALYQAKDRGRDQVVLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP19</accession>
    <name>B1KP19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327367.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4801"/>
    <dbReference type="EnsemblBacteria" id="ACA89050">
        <property type="protein sequence ID" value="ACA89050"/>
        <property type="gene ID" value="Swoo_4801"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4801"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_6_6"/>
    <dbReference type="OMA" id="WGSEFQY"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="182" mass="20764" checksum="C07FB3B387A19B7E" modified="2008-04-29" version="1">MEPLFQTERITCRQFESGDLQAFADYRALPEVAKYQSWSEYSYQDALTLFDEIKGVEFGCLGHWFQLAILTKDSKQMLGDLAVHFIDGEQIEIGFTFAPDFQGQGYASEAVIGLLTYLFSTLKPHRVIATTDCENLPSWLLLERVGFRREAHFIENVFFKGAWGSEFQYAMLASEWRSGNGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP30</accession>
    <name>B1KP30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327378.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4812"/>
    <dbReference type="EnsemblBacteria" id="ACA89061">
        <property type="protein sequence ID" value="ACA89061"/>
        <property type="gene ID" value="Swoo_4812"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4812"/>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_2_1_6"/>
    <dbReference type="OMA" id="MARMKFV"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="196" mass="21140" checksum="57FDD5113BF02C18" modified="2008-04-29" version="1">MAVMKFLCDTKRCIECNGCVTACKNENDSALEWGIQRRRVVTINDGEPGEASISVACMHCTDAPCQAVCPADCFYRTDDGIVLHNKDTCIGCGYCLYACPFGAPQFPKKGAFGSRGKMDKCTFCAGGPEKNFSEAEREKYGANRIAEGKLPMCAEMCSTKSLLAGDAEIVSNIYRERVAARGNPGAIWGYTPKVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPI4</accession>
    <name>B1KPI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-isopropylammelide isopropylaminohydrolase</fullName>
            <ecNumber evidence="2">3.5.4.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.4.42" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324483.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1853"/>
    <dbReference type="EnsemblBacteria" id="ACA86137">
        <property type="protein sequence ID" value="ACA86137"/>
        <property type="gene ID" value="Swoo_1853"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1853"/>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031758_0_1_6"/>
    <dbReference type="OMA" id="YGLPRVN"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018764">
        <property type="term" value="F:N-isopropylammelide isopropylaminohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="52"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="432" mass="48449" checksum="C582D457B04B472B" modified="2008-04-29" version="1">MPAANMLIQNITLQGKQGLHQILIEGGKFQTIAPMTEHLHFSSADISGEHLDGEGGMAIAPFCEPHVHLDTTQTAGEPSWNISGTLFEGIERWSERKSMLSIEDVKSRAKQTLKWQIANGIQHVRTHVDVSDPTLIALKAMLEVKEEMKQWVDIQIVAFPQEGILSYPNGKELLEEAVKLGADVIGAIPHFEFTREYGVESLHFVFELARKYDRLIDVHCDEIDDEQSRFVETVAALAHKYDMGERVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLAANINVCFGHDDIFDPWYPLGTANMLQVLHMGLHVCQIMGYEQINDSLALISSKSARTLNIQNSYGIEIGKPGSLLILPADNGFDAVRRQVPVRYSVRHGKLLAETQVATTQIHLEAAENITFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPN0</accession>
    <name>B1KPN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1899</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324529.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1899"/>
    <dbReference type="EnsemblBacteria" id="ACA86183">
        <property type="protein sequence ID" value="ACA86183"/>
        <property type="gene ID" value="Swoo_1899"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1899"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="ADRANDW"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="228" mass="25138" checksum="FF15FBCFCEB127D4" modified="2008-04-29" version="1" precursor="true">MIKVNGLTKEYQMGNTSVFALRGVEFTINHNEFVAIMGPSGSGKSTLMNIIGCLDKPTSGSYQLNEQEVASLDDDALSAVRNKEIGFVFQSFHLLPRMSALQNVLLPLRFSNPPNQDSQYASELLTRVGLGTRQDHRPNQLSGGQRQRVAIARALVNRPAILLADEPTGALDSKTSVEIMDLFTDLHKAGQTIILVTHEEEVAAYAQRVIRMRDGHIVEIEDRSTYAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS5</accession>
    <name>SYA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="1">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">alaS</name>
        <name type="ordered locus">Swoo_3339</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325943.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPS5"/>
    <dbReference type="SMR" id="B1KPS5"/>
    <dbReference type="STRING" id="392500.Swoo_3339"/>
    <dbReference type="EnsemblBacteria" id="ACA87608">
        <property type="protein sequence ID" value="ACA87608"/>
        <property type="gene ID" value="Swoo_3339"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3339"/>
    <dbReference type="eggNOG" id="COG0013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_1_1_6"/>
    <dbReference type="OMA" id="YHHTMFE"/>
    <dbReference type="OrthoDB" id="91428at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000347795" description="Alanine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="562"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="566"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="668"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <sequence length="874" mass="95119" checksum="134FEA0294A2BAFF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ11</accession>
    <name>SECB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-export protein SecB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">secB</name>
        <name type="ordered locus">Swoo_4875</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SecB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327441.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ11"/>
    <dbReference type="SMR" id="B1KQ11"/>
    <dbReference type="STRING" id="392500.Swoo_4875"/>
    <dbReference type="EnsemblBacteria" id="ACA89124">
        <property type="protein sequence ID" value="ACA89124"/>
        <property type="gene ID" value="Swoo_4875"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4875"/>
    <dbReference type="eggNOG" id="COG1952">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111574_1_0_6"/>
    <dbReference type="OMA" id="CPNVLFP"/>
    <dbReference type="OrthoDB" id="1624074at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00821">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003708">
        <property type="entry name" value="SecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035958">
        <property type="entry name" value="SecB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36918">
        <property type="entry name" value="PTHR36918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02556">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01594">
        <property type="entry name" value="SECBCHAPRONE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54611">
        <property type="entry name" value="SSF54611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00809">
        <property type="entry name" value="secB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0811">Translocation</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000195348" description="Protein-export protein SecB">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00821"/>
        </source>
    </evidence>
    <sequence length="163" mass="17843" checksum="9E32572F62F9B4E6" modified="2008-04-29" version="1">MAEVANNEQQDPQFNIQRVYTKDISFETPNSPAVFQKEWTPEVKLDLDTRSAKLADNVFEVVLSLTVTAKNGEETAFLCEVQQAGIFAINGLTEQQLAHSLGAYCPNILFPYAREAVGSLVARGTFPQLNLAPVNFDALFAQYVNQRQAGAEEAAAKTEEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ74</accession>
    <name>B1KQ74_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome bo(3) ubiquinol oxidase subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cytochrome o ubiquinol oxidase subunit 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Oxidase bo(3) subunit 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Ubiquinol oxidase polypeptide III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquinol oxidase subunit 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">Swoo_0431</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323078.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0431"/>
    <dbReference type="EnsemblBacteria" id="ACA84729">
        <property type="protein sequence ID" value="ACA84729"/>
        <property type="gene ID" value="Swoo_0431"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0431"/>
    <dbReference type="eggNOG" id="COG1845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044071_3_0_6"/>
    <dbReference type="OMA" id="SIYWWGS"/>
    <dbReference type="OrthoDB" id="1502742at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02863">
        <property type="entry name" value="Ubiquinol_oxidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014206">
        <property type="entry name" value="Cyt_c_ubiqinol_oxidase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033946">
        <property type="entry name" value="Ubiquinol_oxase_su3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02842">
        <property type="entry name" value="CyoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="18">
        <location>
            <begin position="38"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACA84729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="215" mass="23910" checksum="CC20E91E40FB0A5A" modified="2008-04-29" version="1">MSIAIRANLGVADANKHYDVSHATSHDEHHDTSENTLFGFWLYLMTDCILFASVFATYAVLYMNTDGGVSGKDIFELNFVLIETAALLVSSITFGFALICAKHQKKAATLGWLLITFALGCAFIGMEIYEFHHLIEHGNGPQRSAFLSSFFALVGMHGLHVTAGLVWMAIMMFEVLKTGLNKRSITRLGCLSLFWHFLDIVWICVFTVVYLLGAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQG2</accession>
    <name>B1KQG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TatD-related deoxyribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323165.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0520"/>
    <dbReference type="EnsemblBacteria" id="ACA84817">
        <property type="protein sequence ID" value="ACA84817"/>
        <property type="gene ID" value="Swoo_0520"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0520"/>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_1_2_6"/>
    <dbReference type="OMA" id="NEPCALP"/>
    <dbReference type="OrthoDB" id="915852at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="29481" checksum="266146D896EE933E" modified="2008-04-29" version="1">MSEHIDIAVNLIGSALEKNCDEVIQRAVAHGVSPLIVIGSDLNESQQAITLCQQYPKTLYSTAGTHPHQASQWDDTSADKIRVLAQAAEVVAIGECGLDYNRDFSPRAKQREAFRAQLALAVELKLPVLMHERDAHEDFLAILKEYRSGLTNALLHCFTGNRESMEAYLELDLHLGITGWVCDERRGLELAELVRDIPDDRILIETDSPYLLPRSMRPKPKSSKNEPQYLPYIAQYIATLREQNPTEFAAKTYQNSVKFFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ1</accession>
    <name>B1KQJ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324576.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1946"/>
    <dbReference type="EnsemblBacteria" id="ACA86230">
        <property type="protein sequence ID" value="ACA86230"/>
        <property type="gene ID" value="Swoo_1946"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1946"/>
    <dbReference type="eggNOG" id="ENOG50331NB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126055_0_1_6"/>
    <dbReference type="OMA" id="SCDSTEF"/>
    <dbReference type="OrthoDB" id="1952072at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021284">
        <property type="entry name" value="DUF2750"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11042">
        <property type="entry name" value="DUF2750"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="13516" checksum="70B9539DF74AB5F5" modified="2008-04-29" version="1">MTEINPILASFIEDVKQHQAVWGLQDESGEGWVVCDSSEYEDTDVMPLWSTEAQAKVHCNDEWANYQPVAIGLTDLLEFWISDLNEDGVLIGTNWQEDQECLEMDPIILAKSLVNVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQN6</accession>
    <name>B1KQN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent transcriptional regulator, MalT-like, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1991"/>
    <dbReference type="EnsemblBacteria" id="ACA86275">
        <property type="protein sequence ID" value="ACA86275"/>
        <property type="gene ID" value="Swoo_1991"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1991"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1336760_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="123"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="205" mass="23097" checksum="0A21024A61C74E89" modified="2008-04-29" version="1">MQTLLLYTSIEWRGVIFLCDNSSIDGIYLGGGGMESSVLGNLLREVEIELALKKMHSEIEHYIKVHHNEKVIYIAESLLCDCVRTSSNHDMYPAIQYVVINELLKEVLLNKTTSDEPQSNEGECISTIELTQRQHEILHWVKLGKSNWEISTILSISIDTVKFHLRGIYKRLGVSNRVQAVQVVTASDLDSLDLGSLVNILKATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQP3</accession>
    <name>B1KQP3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324628.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1998"/>
    <dbReference type="EnsemblBacteria" id="ACA86282">
        <property type="protein sequence ID" value="ACA86282"/>
        <property type="gene ID" value="Swoo_1998"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1998"/>
    <dbReference type="eggNOG" id="COG4990">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_771370_0_0_6"/>
    <dbReference type="OMA" id="RYHEDVA"/>
    <dbReference type="OrthoDB" id="1637025at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026935">
        <property type="entry name" value="BtrH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032369">
        <property type="entry name" value="DUF4872"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14399">
        <property type="entry name" value="BtrH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16169">
        <property type="entry name" value="DUF4872"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BtrH_N" evidence="1">
        <location>
            <begin position="27"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4872" evidence="2">
        <location>
            <begin position="165"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="39377" checksum="53DA92B37F49AF0E" modified="2008-04-29" version="1">MNDTLLSSSQPSAQISTNVYVHATGKHCESTCQRNILLSLGIDIEENIIFGLDASFGFAYHTVQGNSADIVLGKQAIFPMNAARLMGIDVEIHQSAGPSVLIELLKKYTAVITRVDISLLPYWGLAGKAPFGGYFINIIDYDEQSDWFEVSDSSFTDTQWIDSSELCKARSSTLSPPINPANWCCVFKSVKRQPNLHTIGPIAAKNLCREVLKPNFRNLGIPGIKKLAKSAQNWPNTKRGSVDDVDGDGNPVRSDALTRQLVYLGRQIELFGTGGGLFRLMISDFLTHIAKINNNETILKAAELFTESGILWQSVGQELLALSPLSSSETTDSTLKMLIHELAKIEAIEKSALEKLAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT8</accession>
    <name>B1KQT8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326029.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3426"/>
    <dbReference type="EnsemblBacteria" id="ACA87694">
        <property type="protein sequence ID" value="ACA87694"/>
        <property type="gene ID" value="Swoo_3426"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3426"/>
    <dbReference type="eggNOG" id="COG3809">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1509592_0_0_6"/>
    <dbReference type="OMA" id="TIWYEKC"/>
    <dbReference type="OrthoDB" id="1847417at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027392">
        <property type="entry name" value="TF_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13453">
        <property type="entry name" value="zf-TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-TFIIB" evidence="1">
        <location>
            <begin position="13"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="zf-TFIIB" evidence="1">
        <location>
            <begin position="81"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="21025" checksum="A8E6EDE67A9C8A60" modified="2008-04-29" version="1">MEKWIFFKGFKMKCPRTNTDLTSVKVGGITVDISEACGGVFFDNHELEHFDEKHERRGQVLVEHLSQFVPPQLNLSERISCPKCTDVVMARHFYSPEHLVEIDECPGCGGIWFDYAELEKLREQFPNQRDRQRVGERFVSQMETSSRYITHQRELESKEELASRLRRRGLYFIDFFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR57</accession>
    <name>B1KR57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0578"/>
    <dbReference type="EnsemblBacteria" id="ACA84874">
        <property type="protein sequence ID" value="ACA84874"/>
        <property type="gene ID" value="Swoo_0578"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0578"/>
    <dbReference type="eggNOG" id="COG1524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_308337_0_0_6"/>
    <dbReference type="OMA" id="AHFTGPF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="973" mass="110428" checksum="DE77BC04ED6A1E25" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR89</accession>
    <name>B1KR89_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0610"/>
    <dbReference type="EnsemblBacteria" id="ACA84906">
        <property type="protein sequence ID" value="ACA84906"/>
        <property type="gene ID" value="Swoo_0610"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0610"/>
    <dbReference type="eggNOG" id="COG2064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056917_3_0_6"/>
    <dbReference type="OMA" id="FPDFMDM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="144"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="281" mass="31554" checksum="9488A41E8507A702" modified="2008-04-29" version="1" precursor="true">MMLILIMVLIAISGLLALGLALWHQEKQRQWHIQRYLETSQESGLEKLSKLVVRVGQEKREELEQQFIEAGFYDTRFARFYVPAKIGLALVIILLIVISDMTLSNKVMIGAVAMVMTLIVPDSILAMRKKMLVKKTSRQLPYMLDMMSVCVQTGMTVEAALAYLAEELKAFDKDLCFHIKKTADTSRITGLEKALLELSERIPTPEVRSFSLTLIQNIQYGTSIANVLADLAEDMRQMQVLAMEESIGKLAAKMSVPLILFIMFPIVVLILAPGFMQLSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD1</accession>
    <name>B1KRD1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2054</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2054"/>
    <dbReference type="EnsemblBacteria" id="ACA86338">
        <property type="protein sequence ID" value="ACA86338"/>
        <property type="gene ID" value="Swoo_2054"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2054"/>
    <dbReference type="eggNOG" id="ENOG502ZASQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1004348_0_0_6"/>
    <dbReference type="OMA" id="LYANSAR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="30187" checksum="57563D9C4ED0695C" modified="2008-04-29" version="1" precursor="true">MVKNSLILAKFELKKLLFNPRGLISLFAFSLVWLLILLYPIRSASSFLLTEEFRQLISAVFGENSINELFKWEVAEMAVFWIAALYLFPLFSIFVSADQFASDKSRGTFRFLSLRTGRDSIFFGRFTGHMLIQSLLLILTILATVILAASRDMSLLLPALSSGALVFINLFIILLPYTAMMAILSLYANTARQATIYAILFWAISAIIIAIINSQLPSLAELIQWVLPGAQLSMMINTQGFGSFVYAPIPLIQAAVLLFLGRSYMNRSSL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF9</accession>
    <name>HIS6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="1">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ImGP synthase subunit HisF</fullName>
            <shortName evidence="1">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisF</name>
        <name type="ordered locus">Swoo_2082</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324711.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRF9"/>
    <dbReference type="SMR" id="B1KRF9"/>
    <dbReference type="STRING" id="392500.Swoo_2082"/>
    <dbReference type="EnsemblBacteria" id="ACA86366">
        <property type="protein sequence ID" value="ACA86366"/>
        <property type="gene ID" value="Swoo_2082"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2082"/>
    <dbReference type="eggNOG" id="COG0107">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_4_0_6"/>
    <dbReference type="OMA" id="IFHYKET"/>
    <dbReference type="OrthoDB" id="1522718at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000135047" description="Imidazole glycerol phosphate synthase subunit HisF">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <sequence length="257" mass="28635" checksum="AC407470508FE995" modified="2008-04-29" version="1">MLAKRIVPCLDVREGKVVKGVQFRNHEIVGDIVPLAARYAEEGADELVFYDITASAHDRVIDKSWVSRVAERIDIPFCVAGGISSIEQAREKLAFGADKISVNSPALSDPSLIQRLQDEFGRQCIVIGIDSYYDEASDSYRVKQFTGDESATKDTQWFTQNWVEEVQKRGCGEIVLNVMNQDGVRQGYDLKQLSIIREICDVPLIASGGAGTMEHFKDVFEIAKVDAALAASVFHKGIIDINELKTYLAQHKIPTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRM1</accession>
    <name>B1KRM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326119.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3522"/>
    <dbReference type="EnsemblBacteria" id="ACA87786">
        <property type="protein sequence ID" value="ACA87786"/>
        <property type="gene ID" value="Swoo_3522"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3522"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_9_1_6"/>
    <dbReference type="OMA" id="GIITWKD"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="83"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="15100" checksum="935C73637358E001" modified="2008-04-29" version="1">MDIQVSEIMTSRVVTIDMDDRLSVAKEIFDNAPFHHLLVVEHNQLQGVLSERDFLRALSPNIGNINETERDSDTLLKRAHQVMARNPITIEAKENINCASKLLLEHGIGSLPVLEQGELVGIITWKDLLRAYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCW5</accession>
    <name>B1KCW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322689.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0039"/>
    <dbReference type="EnsemblBacteria" id="ACA84340">
        <property type="protein sequence ID" value="ACA84340"/>
        <property type="gene ID" value="Swoo_0039"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0039"/>
    <dbReference type="eggNOG" id="COG1652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050533_1_1_6"/>
    <dbReference type="OMA" id="PELWGMN"/>
    <dbReference type="OrthoDB" id="1833920at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766953" evidence="1">
        <location>
            <begin position="23"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="33"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="369" mass="41023" checksum="72247942F2C29DF3" modified="2008-04-29" version="1" precursor="true">MENPMKRLILFALMTFSCSIFADTLTLKSGHPDSYVVVKGDTLWDISEHFLNDPWRWPKLWGVNPQIANPHLIYPGDRLTLVFIDGEPRLVVKPHKRKSPEGRIHAKGDAIPAIDLSLIGPYLIQNRVVDGDWFDKQPMVLGGESESKHHIVGDIVYVQQVLTLGDKFGVYSEGREFVSKENEVLGKEVVLTASGRVVESGPISKIKLLSNFRETKAGYRILPIESDSLLSAYFMPKAATVTEPGSILASEKHLREMGKLDVVYLDKGVEDGVEPGDVFSIYRDGIDVVINGDGQPVLPAERSSYEDLLSGVSSDNAIKMPDIFRGRLMVFKVFDKTSLGLIMANKKTVRVDDKLVQPDSINLLKSFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD20</accession>
    <name>B1KD20_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326188.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3591"/>
    <dbReference type="EnsemblBacteria" id="ACA87855">
        <property type="protein sequence ID" value="ACA87855"/>
        <property type="gene ID" value="Swoo_3591"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3591"/>
    <dbReference type="HOGENOM" id="CLU_1155768_0_0_6"/>
    <dbReference type="OrthoDB" id="1603808at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="240" mass="27176" checksum="8D0D6FEEC918D344" modified="2008-04-29" version="1">MEVNADIKKIRKLGITIRGLLWIICGGIVLSNIGFFLFYDFFNLDFEFFSRASIFGFQVMLDELTISSDSPYPIQVSIHDSPNLLVKWLWYISTPACLIITLFIILRLDKLFKSYSEGMVFHSSNTKGLAVIGWLLVGLYFTDAIASMTLETLFLDASNSFIVVEELPHMVPIDPTSEAKMIDLDCMPPEMADLEFPPLPEMGTRIYSNLTLLLFGSFLIVVARIMSYAENLKKEVDTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD68</accession>
    <name>B1KD68_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326236.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3641"/>
    <dbReference type="EnsemblBacteria" id="ACA87903">
        <property type="protein sequence ID" value="ACA87903"/>
        <property type="gene ID" value="Swoo_3641"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3641"/>
    <dbReference type="eggNOG" id="COG3056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113316_0_0_6"/>
    <dbReference type="OMA" id="NNIYQDQ"/>
    <dbReference type="OrthoDB" id="1505435at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005619">
        <property type="entry name" value="Uncharacterised_YajG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03923">
        <property type="entry name" value="Lipoprotein_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766958" evidence="1">
        <location>
            <begin position="19"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="20855" checksum="2589DFC1FC80B302" modified="2008-04-29" version="1" precursor="true">MKSLFLSLIALVVLSGCASQMPSHIALNPQIPDIQTQSHSLQPLALETIDTRPANFIVRFNNGDEAAKLVSPSEAPRRQMDEVFREGLIKAGYQVTPSSMKQVQFQLEQLLTDVNDTTFGYEANSNIVINVIAKNDRDTLTKRYTARNTVTGPFSADFATLELAINKLLDELSSKILTDPELNTFIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD79</accession>
    <name>B1KD79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3652</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326247.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3652"/>
    <dbReference type="EnsemblBacteria" id="ACA87914">
        <property type="protein sequence ID" value="ACA87914"/>
        <property type="gene ID" value="Swoo_3652"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3652"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013154_0_0_6"/>
    <dbReference type="OMA" id="SHHAKAM"/>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023155">
        <property type="entry name" value="Cyt_c-552/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010177">
        <property type="entry name" value="Paired_CXXCH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13435">
        <property type="entry name" value="Cytochrome_C554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09699">
        <property type="entry name" value="Paired_CXXCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764700" evidence="3">
        <location>
            <begin position="23"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_C554" evidence="5">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="4">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="598"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="632"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="729" mass="82050" checksum="B7EDE5A73C3BE659" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD94</accession>
    <name>B1KD94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3667</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326262.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3667"/>
    <dbReference type="EnsemblBacteria" id="ACA87929">
        <property type="protein sequence ID" value="ACA87929"/>
        <property type="gene ID" value="Swoo_3667"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3667"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_6"/>
    <dbReference type="OMA" id="IIEWRAF"/>
    <dbReference type="OrthoDB" id="1045165at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="27425" checksum="6DE48BF73C5CDE28" modified="2008-04-29" version="1">MNFREKHNLTHQLTHDLGMEVVKGNYAVGGGLPSEADICSLYNVSRSATREAVKMLSAKGLITSRPKQGIRVMPEHNWNLFDTDVLSWILSSKPSIQLLHEFTQMRVAIEPQACALAAVHANAEQLRNIEDALNRMRDADNGLDDPLEADIAFHTSILEASCNRFFYQLTNFIATALRVSIRYTNKIKGVHGADVLKHQHILDTIKSRDSESAYKASKEILDEAIELIETQFVERTISVPVVNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM2</accession>
    <name>B1KDM2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2135"/>
    <dbReference type="EnsemblBacteria" id="ACA86419">
        <property type="protein sequence ID" value="ACA86419"/>
        <property type="gene ID" value="Swoo_2135"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2135"/>
    <dbReference type="eggNOG" id="ENOG5033BZN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_185065_1_0_6"/>
    <dbReference type="OMA" id="LMYQGHA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021363">
        <property type="entry name" value="DUF2835"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11197">
        <property type="entry name" value="DUF2835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="74" mass="8980" checksum="BD73CAB77A85F2F3" modified="2008-04-29" version="1">MYIMIFYFSINVNYQEFERYYQGHADKVEVRDNEGRILWIHGRHFRPFLTRTGVQGQFKMELSQSGELLSLFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM6</accession>
    <name>B1KDM6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2139</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324768.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2139"/>
    <dbReference type="EnsemblBacteria" id="ACA86423">
        <property type="protein sequence ID" value="ACA86423"/>
        <property type="gene ID" value="Swoo_2139"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2139"/>
    <dbReference type="eggNOG" id="COG1033">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008861_4_0_6"/>
    <dbReference type="OMA" id="LHFVSHF"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="612"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="637"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="661"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="707"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="741"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="220"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="770" mass="83800" checksum="F98187823EA42DF8" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ8</accession>
    <name>B1KDQ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324799.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2173"/>
    <dbReference type="EnsemblBacteria" id="ACA86455">
        <property type="protein sequence ID" value="ACA86455"/>
        <property type="gene ID" value="Swoo_2173"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2173"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063829_0_0_6"/>
    <dbReference type="OMA" id="QQWKLDS"/>
    <dbReference type="OrthoDB" id="951478at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017685">
        <property type="entry name" value="ArgP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03298">
        <property type="entry name" value="argP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="33567" checksum="EEB090FE1B2FF826" modified="2008-04-29" version="1">MLDYAHLHALAVVISEGGFERASKILCISQPAVSQRIKQLEERVGQALVIRSTPVEATPTGKRLLRHYSQVQLLESELSVEMDADDPKLPTIVKIAVNADSLATWFLPALSEIFKRHQWLLELIVDDESYTHNLLKNGEAVGCVTTTKEPLAGCSSEYLGEMEYLCVATPEFIQQYFPINITPTSLERAPAVVFSTKDKLHEKYLKKYFKMKTGSWREHKIPSSESFLEAIIQGMGYGLVGHLQAEPLIERGILIEITPDKRKRVPLYWQHWNIKAKQTTIVYRSLAVTAKQSLCQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDS4</accession>
    <name>B1KDS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arsenate reductase and related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324815.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2189"/>
    <dbReference type="EnsemblBacteria" id="ACA86471">
        <property type="protein sequence ID" value="ACA86471"/>
        <property type="gene ID" value="Swoo_2189"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2189"/>
    <dbReference type="eggNOG" id="COG1393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116644_2_1_6"/>
    <dbReference type="OMA" id="FGIKNCD"/>
    <dbReference type="OrthoDB" id="1606021at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006504">
        <property type="entry name" value="Tscrpt_reg_Spx/MgsR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01617">
        <property type="entry name" value="arsC_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="13100" checksum="18A412C930555B0F" modified="2008-04-29" version="1">MTLFGIKNCDTVKKARKWTEANGLNIPFHDFRVDGLTKEQLESWVETLGWEPLFNKRSTSFRNLSDEEKSDIDQAKAIELMLTHPTLIKRPVLAADGKALVGFKEAEYKAWFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU7</accession>
    <name>B1KDU7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prs</name>
        <name evidence="8" type="ordered locus">Swoo_3689</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3689"/>
    <dbReference type="EnsemblBacteria" id="ACA87949">
        <property type="protein sequence ID" value="ACA87949"/>
        <property type="gene ID" value="Swoo_3689"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3689"/>
    <dbReference type="eggNOG" id="COG0462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033546_2_0_6"/>
    <dbReference type="OMA" id="FGWARQD"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="13"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="233"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="46"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="105"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="35125" checksum="BB186951A8F03F7F" modified="2008-04-29" version="1">MKHTPEVDTVPDIKLFAGNATPSLAKKIADRLFCKLGDADVGVFSDGEISVQINENVRGADVFIIQSTCAPTNDNLMELIVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTCDLHAEQIQGFFDVPVDNVFGSPVLLEDMLDKKLENPVVVSPDIGGVVRARAVAKLLDDSDLAIIDKRRPQANVAQVMHIIGDVQGRDCIIVDDMIDTGGTLCKAAEALKEHGANRVFAYATHPVFSGNAAKNIAESVIDEVIVTDTIPLSKEIQALDKVTQLTMSTLMAEAIRRVSNEESISAMFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV0</accession>
    <name>B1KDV0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ychF</name>
        <name evidence="7" type="ordered locus">Swoo_3692</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326284.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3692"/>
    <dbReference type="EnsemblBacteria" id="ACA87952">
        <property type="protein sequence ID" value="ACA87952"/>
        <property type="gene ID" value="Swoo_3692"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3692"/>
    <dbReference type="eggNOG" id="COG0012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018395_0_1_6"/>
    <dbReference type="OMA" id="VLRCFDN"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="3"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="278"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="363" mass="39276" checksum="2268039B67BE8164" modified="2008-04-29" version="1">MGFKCGIVGLPNVGKSTLFNALTKAGIEASNFPFCTIEPNTGVVPVPDARLDALAQIVNPERVLPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFEDDNIVHVANKVSPASDIEVINTELALADLDSCERAITRQAKRAKGGDADAKFEVSVLEKMRPVLDEGDMLRSMELSKEELAAVAYLNFLTLKPTMYIANVAEDGFENNPHLDTVREIAAKENAVVVAVCAAIESELAEMDAEDREEFMADLGLEEPGLDRVIRAGYDLLTLQTYFTAGVKEVRAWTVPVGASAPKAAGVIHTDFERGFIRAQVMAYDDFITYKGEAGAKEAGKLRVEGKTYIVKDGDVMHFLFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE02</accession>
    <name>B1KE02_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326336.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3745"/>
    <dbReference type="EnsemblBacteria" id="ACA88004">
        <property type="protein sequence ID" value="ACA88004"/>
        <property type="gene ID" value="Swoo_3745"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3745"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_3_4_6"/>
    <dbReference type="OMA" id="SDAMHFK"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071518">
        <property type="term" value="F:autoinducer-2 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009372">
        <property type="term" value="P:quorum sensing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07775">
        <property type="entry name" value="FGGY_AI-2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033676">
        <property type="entry name" value="AI-2_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="292"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="525" mass="57399" checksum="D8C3A00155AF9042" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE16</accession>
    <name>B1KE16_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LPD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326350.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3759"/>
    <dbReference type="EnsemblBacteria" id="ACA88018">
        <property type="protein sequence ID" value="ACA88018"/>
        <property type="gene ID" value="Swoo_3759"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3759"/>
    <dbReference type="eggNOG" id="COG1040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094219_0_0_6"/>
    <dbReference type="OMA" id="HEWFHAF"/>
    <dbReference type="OrthoDB" id="1664446at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041047">
        <property type="entry name" value="LPD1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18796">
        <property type="entry name" value="LPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LPD1" evidence="1">
        <location>
            <begin position="182"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="260" mass="29072" checksum="16D260EF2DFCBE6A" modified="2008-04-29" version="1">MLKHKEYRREGPDYRFGEQVSFNDIKQTFNLNHIRIGSWVEEDEKHKAANLIFDSLADLAFILKLPPHALGLRQTLNLAFGSGGQKGVQAHYIPAHRELALAKNAGAGALAHEFWHAFDHYISSKSYHISPVGISFASHCWLADVRPIAHPLNQRLEQVFTTALLTDDGGDANDFVTRGLALDKQYGGQYFSKPTELMARAFEACIESYPDISNPYLVNETLTSSLATAGGYPDLQHRKQIFAALIGYFEPLGEAIEREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE22</accession>
    <name>B1KE22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323355.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0713"/>
    <dbReference type="EnsemblBacteria" id="ACA85008">
        <property type="protein sequence ID" value="ACA85008"/>
        <property type="gene ID" value="Swoo_0713"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0713"/>
    <dbReference type="eggNOG" id="ENOG5031ZNY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_205285_0_0_6"/>
    <dbReference type="OMA" id="MRYLEFS"/>
    <dbReference type="OrthoDB" id="2013305at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="58" mass="6740" checksum="CBA4E657FA72A046" modified="2008-04-29" version="1">MSDEILGLDQVCEILGKPEATIKRYARESLLTNIGDEDEFKFNKEEVMRYLDFAKRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE34</accession>
    <name>B1KE34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0719 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323367.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0725"/>
    <dbReference type="EnsemblBacteria" id="ACA85020">
        <property type="protein sequence ID" value="ACA85020"/>
        <property type="gene ID" value="Swoo_0725"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0725"/>
    <dbReference type="eggNOG" id="COG3766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080987_0_0_6"/>
    <dbReference type="OMA" id="RYLQGWT"/>
    <dbReference type="OrthoDB" id="1293024at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007140">
        <property type="entry name" value="DUF350"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03994">
        <property type="entry name" value="DUF350"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="32600" checksum="0AAA20AB4CDAA475" modified="2008-04-29" version="1">MTLFQDFGITQDLVIILAIDLTIAIILLTFMRYLQGWTIKVDSRVELSEKDNFAFGISTAGAIAGLGIVLTGAITGEAAHSYLVEAVGMTAYGLFGLILIKLGRYLHDKIALNEFNKSELILKGNISVAIVDASAAIATAIIIRSVLLWAEDLTLDTFIAIFSAFAISQLMLVLLTRFREHRYAKRNQNASMQEALVQGHKAVAIRHSGYMLAMALSFNAASHFIIYSPQAYLANIAGWMVFSVIMLIALTLLIKLVKKLVMVNINLAEEVEKQHNIGVATVELALSVAIALILTSLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE72</accession>
    <name>B1KE72_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar biosynthesis protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0763"/>
    <dbReference type="EnsemblBacteria" id="ACA85058">
        <property type="protein sequence ID" value="ACA85058"/>
        <property type="gene ID" value="Swoo_0763"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0763"/>
    <dbReference type="eggNOG" id="COG0727">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051643_1_1_6"/>
    <dbReference type="OMA" id="YLKEFKC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="394" mass="44658" checksum="2280C754DD6626C3" modified="2008-04-29" version="1">MMDSGIVTPKYVSDFSCIGPDCEDSCCIGWNIYIDKQSYKKTMAHRELKPLAKTAMKKIKKSDEQWAIIRSDAQGACPFLDSNRLCKIHALAGEQTLSETCKTYPRTSLVREGDKYRSLSLSCPEAARLILFSPDAFIFERKESGANIMSESSPLWVAKTYDNSIDLLLNEKLNWQEALLAIGFLVNTADKVWANEVGAEQIDVRLEQLIQMAEKGMLQEQYQTLAYADEHQVQAFASIHGMFIDEHPRRDGVRFKTVNDAISTLLNDDRTVDVDKINHAWNTIASPALEEHGDIFKRYILYYIYHEYFPITLGEAPQSAFRLLVLDCFMLRCYLAVIAHKNNGLSESDVILCFQVYHVVRQHKSTFVKGATAMMEKFNFSNIAGIISLLKTGS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-11-03" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE86</accession>
    <name>CYSI_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfite reductase [NADPH] hemoprotein beta-component</fullName>
            <shortName evidence="1">SiR-HP</shortName>
            <shortName evidence="1">SiRHP</shortName>
            <ecNumber evidence="1">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysI</name>
        <name type="ordered locus">Swoo_0777</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 H2O + hydrogen sulfide + 3 NADP(+) = 4 H(+) + 3 NADPH + sulfite</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
        <text evidence="1">Binds 1 siroheme per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="ACA85072" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85072.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_041417944.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KE86"/>
    <dbReference type="SMR" id="B1KE86"/>
    <dbReference type="STRING" id="392500.Swoo_0777"/>
    <dbReference type="PRIDE" id="B1KE86"/>
    <dbReference type="EnsemblBacteria" id="ACA85072">
        <property type="protein sequence ID" value="ACA85072"/>
        <property type="gene ID" value="Swoo_0777"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0777"/>
    <dbReference type="eggNOG" id="COG0155">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001975_3_2_6"/>
    <dbReference type="OrthoDB" id="1588103at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009337">
        <property type="term" value="C:sulfite reductase complex (NADPH)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01540">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011786">
        <property type="entry name" value="CysI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="PTHR11493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02041">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000388519" description="Sulfite reductase [NADPH] hemoprotein beta-component">
        <location>
            <begin position="1"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="577" mass="64444" checksum="2FFBB34DB93B0DB3" modified="2009-11-03" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE88</accession>
    <name>B1KE88_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323421.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0779"/>
    <dbReference type="EnsemblBacteria" id="ACA85074">
        <property type="protein sequence ID" value="ACA85074"/>
        <property type="gene ID" value="Swoo_0779"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0779"/>
    <dbReference type="eggNOG" id="ENOG502Z9I7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025721_0_0_6"/>
    <dbReference type="OMA" id="KMRGYIP"/>
    <dbReference type="OrthoDB" id="1071246at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="576" mass="62604" checksum="7E6FC7518BB846B9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEC6</accession>
    <name>B1KEC6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="5">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">asnS</name>
        <name evidence="7" type="ordered locus">Swoo_2223</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324848.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2223"/>
    <dbReference type="EnsemblBacteria" id="ACA86504">
        <property type="protein sequence ID" value="ACA86504"/>
        <property type="gene ID" value="Swoo_2223"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2223"/>
    <dbReference type="eggNOG" id="COG0017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_0_6"/>
    <dbReference type="OMA" id="DNMDLAE"/>
    <dbReference type="OrthoDB" id="204241at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="139"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="466" mass="52445" checksum="4683258382A2AC70" modified="2008-04-29" version="1">MSITSVASVFKGDFAIGSQVTVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNSLANYNDEILKLTAGCSVVMTGEVVDSPGKGQAFELQVTQVEVAGWVEDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNSLSQAIHRFYNEEGFIWVSTPLITASDCEGAGEMFRVSTLDMENLPRTDEGKVDYSEDFFGKESFLTVSGQLNAETYASALSKVYTFGPTFRAENSNTSRHLAEFWMVEPEVAFADLDDVAGLAEQMLKFCFKAVLEERRDDLEFFAQRVDKTVIERLESFVNSDFAQVDYTDAVEILKNCGKKFEYDVEWGIDLQSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGAQREERLEVLDARLEEMNLSKEDYWWYRDMRRYGTVPHSGFGLGFERLVSYVTGVSNIRDVIPFPRAPKSASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI2</accession>
    <name>B1KEI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transketolase central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324903.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2279"/>
    <dbReference type="EnsemblBacteria" id="ACA86560">
        <property type="protein sequence ID" value="ACA86560"/>
        <property type="gene ID" value="Swoo_2279"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2279"/>
    <dbReference type="eggNOG" id="COG0022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_0_6"/>
    <dbReference type="OMA" id="SEAYYMA"/>
    <dbReference type="OrthoDB" id="900125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="2">
        <location>
            <begin position="4"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="35527" checksum="0D6616C86EB157F6" modified="2008-04-29" version="1">MAEINMLQAINDALSMAMETDDKTILFGEDVGHFGGVFRATSGLQDKYGRDRCFNTPLTEQGIAGFANGLASNGMTAIAEIQFADYIFPAIDQIVNETAKFRYRSGNEFNVGGVTFRTPYGGGIAGGHYHSQSPEAYFTQTAGLKVVVPRNAYQAKGLLLASIRDKNPVIFFEPKRLYRANIGEVPDGDYEIELGKAEVVREGKDITLLAWGAQMEIIEKAADMAAKEGISCEILDLRTLAPWDVETVATSVKKTGRLLINHEAPLTGGFAGEIAATIQEECFLYLESPISRVCGLDTPYPLIHEKEYMPDALKTFEAIKASVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM8</accession>
    <name>B1KFM8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323541.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0900"/>
    <dbReference type="EnsemblBacteria" id="ACA85194">
        <property type="protein sequence ID" value="ACA85194"/>
        <property type="gene ID" value="Swoo_0900"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0900"/>
    <dbReference type="eggNOG" id="ENOG50334Y8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1248691_0_0_6"/>
    <dbReference type="OrthoDB" id="1821957at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="20817" checksum="D2AD13437805AC16" modified="2008-04-29" version="1">MATSFISEHSAEFILVPAMKALLEKKFSVVVPIFPWLSREFGNRAKSTHGFSGFNVLALFPRRPKISDNDEVLVTVNGELSVYKEIGLEHGITVIAGCPVATNLWEFASCNEFAWLDIDDAYGYLESIDSLAGKRLTDEEILATVSKSEVHSMDTLEAFIRDTRYVLPAGFFGTRYKPVYFLVAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV1</accession>
    <name>B1KFV1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323614.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0974"/>
    <dbReference type="EnsemblBacteria" id="ACA85267">
        <property type="protein sequence ID" value="ACA85267"/>
        <property type="gene ID" value="Swoo_0974"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0974"/>
    <dbReference type="HOGENOM" id="CLU_1288158_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="24549" checksum="BD179886F3AFD844" modified="2008-04-29" version="1" precursor="true">MRLIIYIFALVFSGNSFSAHIELSKGAENDVCSKLFSIRLIKATSSFREAAKILARKEGIPEWKQRKLSDGYDSLLNDINYAVFDIDNDGVNEYVYSHFTWMSGQPGEVYTVFNTDAIKSKKDLEAQGFYKQAGLNSVSPEFNYREFGVWFAELIPFRHKGTYYVGIKDIYFGKGEFIDRKFFVAKYSNEMIVGNSGYKTSNLENICTFEYVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW5</accession>
    <name>B1KFW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0988</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323628.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0988"/>
    <dbReference type="EnsemblBacteria" id="ACA85281">
        <property type="protein sequence ID" value="ACA85281"/>
        <property type="gene ID" value="Swoo_0988"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0988"/>
    <dbReference type="eggNOG" id="COG5265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_4_6"/>
    <dbReference type="OMA" id="VTEWRTH"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="34"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="354"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="386"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="591" mass="65460" checksum="7C4CBB434CAFBE7B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFZ1</accession>
    <name>B1KFZ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325040.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2420"/>
    <dbReference type="EnsemblBacteria" id="ACA86698">
        <property type="protein sequence ID" value="ACA86698"/>
        <property type="gene ID" value="Swoo_2420"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2420"/>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_0_3_6"/>
    <dbReference type="OMA" id="CAACGWL"/>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021993">
        <property type="entry name" value="ATPase-cat-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12156">
        <property type="entry name" value="ATPase-cat_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="745"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="767"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="6">
        <location>
            <begin position="93"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="792" mass="86386" checksum="D1A7F1581DFD2781" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFZ3</accession>
    <name>B1KFZ3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cbb3-type cytochrome c oxidase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Swoo_2422</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 17">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="15 17">Binds 2 heme C groups per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 15">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the cbb3-type cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the CcoP / FixP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2422"/>
    <dbReference type="EnsemblBacteria" id="ACA86700">
        <property type="protein sequence ID" value="ACA86700"/>
        <property type="gene ID" value="Swoo_2422"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2422"/>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047545_2_0_6"/>
    <dbReference type="OMA" id="DWLYGGE"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032858">
        <property type="entry name" value="CcoP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038414">
        <property type="entry name" value="CcoP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008168">
        <property type="entry name" value="Cyt_C_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004678">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_su3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14715">
        <property type="entry name" value="FixP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000006">
        <property type="entry name" value="Cbb3-Cox_fixP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00605">
        <property type="entry name" value="CYTCHROMECIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00782">
        <property type="entry name" value="ccoP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 15 17" id="KW-0349">Heme</keyword>
    <keyword evidence="9 15" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="155"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="242"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000006-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000006-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACA86700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="35482" checksum="53227EB9FEFA4F84" modified="2008-04-29" version="1">MALMTDFWSIWISVLTIVVIAGCFILLKLVSKNTTGVEEGESMGHSFDGIEELNNPLPKWWSYMFYITIVFGVVYLALYPGLGNYKGLLGWSSSNQSIGTENGIKADSVAAIELAAKEGRWVQYDQEVKRADEKFGPIFKAYAETPLEELVKNEEALKVGGRLFLQNCSQCHGSDARGSKGFPNLTDNDWLYGGELATIKTSILNGRHGMMPPKGGLPIEDSEVKGLAEYVTKLAGRDHDEALAAQGQASFMKGCFACHGMDATGNKFMGAPNLTNNVWLYGGSRGAIEQSIINGRSGVMPAWKDVLGEEKVHVITAYVYSLSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFZ4</accession>
    <name>B1KFZ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cbb3-type cytochrome oxidase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325043.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2423"/>
    <dbReference type="EnsemblBacteria" id="ACA86701">
        <property type="protein sequence ID" value="ACA86701"/>
        <property type="gene ID" value="Swoo_2423"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2423"/>
    <dbReference type="eggNOG" id="COG4736">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_192294_2_2_6"/>
    <dbReference type="OMA" id="GTIHAIW"/>
    <dbReference type="OrthoDB" id="2085391at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01324">
        <property type="entry name" value="cbb3_Oxidase_CcoQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008621">
        <property type="entry name" value="Cbb3-typ_cyt_oxidase_comp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05545">
        <property type="entry name" value="FixQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="55" mass="6195" checksum="91A0C340B6CE8026" modified="2008-04-29" version="1">MDYGTIQGIITIVVMFTFIGIFAWAYSSCRKDQFDEAANLVFSEDELNKGSGEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFZ5</accession>
    <name>B1KFZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c oxidase, cbb3-type, subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2424</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325044.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2424"/>
    <dbReference type="EnsemblBacteria" id="ACA86702">
        <property type="protein sequence ID" value="ACA86702"/>
        <property type="gene ID" value="Swoo_2424"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2424"/>
    <dbReference type="eggNOG" id="COG2993">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050647_1_0_6"/>
    <dbReference type="OMA" id="GKGATEM"/>
    <dbReference type="OrthoDB" id="1469969at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003468">
        <property type="entry name" value="Cyt_c_oxidase_monohaem-su/FixO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02433">
        <property type="entry name" value="FixO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00781">
        <property type="entry name" value="ccoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="52"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="23306" checksum="9E9B0F3D3CB15B4E" modified="2008-04-29" version="1">MKFNHELVEKNIGLLGIFTVIAISFGGLVQITPLLFQKDTTEPVDGLIPYTALQTEGRDIYIREGCYNCHSQMIRPLRAETERYGHYSVAGESVWDHPFQWGSKRTGPDLARVGGRYSDKWHEVHLIDPRAVVPQSNMPGFPWLAENKLDGKLTGQKMEILRSLHKGGNKGQDLYTDEEIAGAQKAVEGKTEMEALIAYLQSLGHALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG85</accession>
    <name>B1KG85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3965</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CpxP/Spy family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326552.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88222">
        <property type="protein sequence ID" value="ACA88222"/>
        <property type="gene ID" value="Swoo_3965"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3965"/>
    <dbReference type="HOGENOM" id="CLU_1915678_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012899">
        <property type="entry name" value="LTXXQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07813">
        <property type="entry name" value="LTXXQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005661815" evidence="5">
        <location>
            <begin position="24"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="132" mass="14592" checksum="0617EE6874EB3232" modified="2008-04-29" version="1" precursor="true">MKKLTGAIIALTFTVAAATQAYATGFGDRIASKLDLTPEQTVQFQEVQSKRKAQMEDGLKIREQIKALASSGDIDGAAILAGQQAEKKVRTMYALKTELTSFLTKEQIGTLAEIRDHMTEKKERLKKFISNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE5</accession>
    <name>B1KGE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydantoin racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326611.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4026"/>
    <dbReference type="EnsemblBacteria" id="ACA88282">
        <property type="protein sequence ID" value="ACA88282"/>
        <property type="gene ID" value="Swoo_4026"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4026"/>
    <dbReference type="eggNOG" id="COG4126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053002_3_1_6"/>
    <dbReference type="OMA" id="FARPPRK"/>
    <dbReference type="OrthoDB" id="1273626at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036361">
        <property type="term" value="F:racemase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="266" mass="29449" checksum="1F231D2DF578F514" modified="2008-04-29" version="1">MNNQSKIRIRWLNPIAQPHYDEPMGMALKQVANAGTEVEVVSLQSEAKMDNLEYRFYESLVIGDVVKVAKEGDVNGVDAMVIGCFYDLALEDCREICQNTLVVAPCQASMQVAANIANKFSVIVGQVKWIEQMTERAERYGYGGYLASMRSIDMSANSLQCDTQVTTDRIIEAGRLAIEEDHAEALILGCTCNFGLYEKVQQELGVPVIDPLIAALKQAEMLASMKQAFHLAPSNKWSCEPPSESEMLKFGLHSLTESIGNRFLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG1</accession>
    <name>B1KGG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0996</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323636.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0996"/>
    <dbReference type="EnsemblBacteria" id="ACA85289">
        <property type="protein sequence ID" value="ACA85289"/>
        <property type="gene ID" value="Swoo_0996"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0996"/>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_2_1_6"/>
    <dbReference type="OMA" id="HPYNVSL"/>
    <dbReference type="OrthoDB" id="1567509at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026045">
        <property type="entry name" value="Ferric-bd"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002825">
        <property type="entry name" value="CfbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766579" evidence="3">
        <location>
            <begin position="22"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR002825-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="335" mass="37355" checksum="B8F0FD65355153E3" modified="2008-04-29" version="1" precursor="true">MKIIKNLAVLGLVCFASVANAADKLTVYSYRQAFLIDPILNDFTKETGIDVDVVFSKKGIAERMMREGRLSPADVVLTSDFYRLMELVDKELVVPASSELLNSNIPAQYRSPDETWYALTMRVRNIYSSKERLGKLNINYEDLADPKYKGKICTRSGKHPYNISLVASMIAHHGEAETKAWLTGLKANLARKPQGNDRAQVKAVKEGLCDLAIGNSYYLGKMLQDPKQVPWAEAVEINFPNQDNSGSHINVSGMALAKHSRNKDNALKLMEYLSGDKAQKAYAEVNMEYPVKADVEPSALVASWGEFTADSLPIYKLAEFHHAAVKMLDEVKFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGY7</accession>
    <name>B1KGY7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326628.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4043"/>
    <dbReference type="EnsemblBacteria" id="ACA88299">
        <property type="protein sequence ID" value="ACA88299"/>
        <property type="gene ID" value="Swoo_4043"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4043"/>
    <dbReference type="eggNOG" id="COG0819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1145580_0_0_6"/>
    <dbReference type="OMA" id="IEGSRWI"/>
    <dbReference type="OrthoDB" id="1537025at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="25865" checksum="614C3490A949CAEC" modified="2008-04-29" version="1">MTAHVLTTSGQTCLQSLLKVWFDFDLALSKAPIVKRLEQGRLSHEDYQKLLLNLRQQVIEGSRWITRCASSFNREYADVRSIVIGHAKDEHKDFLMLESDYVAVGGDIDVIQNSSKNIGSEALHGFLMYRASQENPVDLIGAMWIIEGLGNKMASKWAQLVEEQLELPKEATQFMRYHGENDEHHLEELYKLVDRVAVDDGAIKAIERTAKVVARLYILQLEEVDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE9</accession>
    <name>B1KHE9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323803.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85457">
        <property type="protein sequence ID" value="ACA85457"/>
        <property type="gene ID" value="Swoo_1164"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1164"/>
    <dbReference type="HOGENOM" id="CLU_1531520_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="19405" checksum="68CD1BF19220B38B" modified="2008-04-29" version="1">MKEVTQQGVDAFLEFVDSNDRELIPYLLHEFSDFISEKPVKAYRGVRYPKSISTDSTIFEPKPVSLVSLSMSRSQAMIFADNSTSIGRRPVKFSGDIGVLYQAKIQGAYLNLHKLATYLVNLACSGLKPEGVCFDPMDKRLQLALTEQELIGSAILIPITQYDGHNLALGFQQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ4</accession>
    <name>B1KHQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325279.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2663"/>
    <dbReference type="EnsemblBacteria" id="ACA86939">
        <property type="protein sequence ID" value="ACA86939"/>
        <property type="gene ID" value="Swoo_2663"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2663"/>
    <dbReference type="HOGENOM" id="CLU_1523189_0_0_6"/>
    <dbReference type="OrthoDB" id="2132263at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767066" evidence="1">
        <location>
            <begin position="33"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20185" checksum="C2183D67343BD341" modified="2008-04-29" version="1" precursor="true">MNIKTRKSPKYIKAATALAVLTCLGISSIAQAVPWCHRGTIVQIADVTWNQAQIMANFTGSIPGGVADTEVYTTYHSTNNYANTFAGGGGGFGGFSVPGSGQVRVIHYAPYTLTNMVGPGYYYTSQGVKFKLDKCYTIPPLMEHKEVARFEPTNPETGIEVVPYEKLEAMQEYWRLSEEQERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ8</accession>
    <name>B1KHQ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sigma54 specific transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326715.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4130"/>
    <dbReference type="EnsemblBacteria" id="ACA88386">
        <property type="protein sequence ID" value="ACA88386"/>
        <property type="gene ID" value="Swoo_4130"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4130"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_6_6"/>
    <dbReference type="OMA" id="TENERDH"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045343">
        <property type="entry name" value="VpsR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20161">
        <property type="entry name" value="VpsR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="134"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="49911" checksum="320B016585605299" modified="2008-04-29" version="1">MKNLLLVSQHYDDCLYQSIKRDGYQITHCDFKELEGICESNQHLGVIDLRGCSDLILIERLLDGIHSHMLIVIIVNRQQLKNTDIKRVIGKYAWDYHTEPIDHGRFFRMLGHASGLSTLKRISQSSLKSENESMLIHSPVMQALDEQISRVAPTDIPVLIRGESGTGKELVALNIHQESRRSSGPFVAVNCGSMVSGLVQSELFGHARGAFTGAVAERKGKIELADTGTLFLDEIGDLPLDQQANLLRFLQEGVFDKVGGTGACKANVRILAATHIDLDVAISKGEFRLDLYYRLNGVTLNTPTLQQRSEDILPLARQFVDVFAREFDFPGCHLTDDACRALQRHDWPGNVRELINRVRRAVVLSDKGRVNAAALDLLSIKEVELLPLKVLKNQVERTAIINAMQFSNGHAEQAAVHLQISRATLYRLLEKHDIDQSEELCLKNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ9</accession>
    <name>B1KHZ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase like protein, AhpD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323823.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1184"/>
    <dbReference type="EnsemblBacteria" id="ACA85477">
        <property type="protein sequence ID" value="ACA85477"/>
        <property type="gene ID" value="Swoo_1184"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1184"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_6_2_6"/>
    <dbReference type="OMA" id="NRFGVTC"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="37"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17586" checksum="9078F9DD2DFD6065" modified="2008-04-29" version="1">MTDVIFNNTRFDPDLTPFHEHAKQMAKAFGYTAALDFDKNLAQLVRLRVAQVNQCSYCLILHSKTAREVGIEPAKIDNLASYWESELYSEQEKVALSYCDRLTQGTDPHFHEIHEQAKCFFSEKEIAELAAIVINMNLWTRLKLAQGATPSYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI06</accession>
    <name>B1KI06_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323830.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1191"/>
    <dbReference type="EnsemblBacteria" id="ACA85484">
        <property type="protein sequence ID" value="ACA85484"/>
        <property type="gene ID" value="Swoo_1191"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1191"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127592_0_2_6"/>
    <dbReference type="OMA" id="MNNVINW"/>
    <dbReference type="OrthoDB" id="1864858at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="122" mass="13473" checksum="320F3CF985D931B5" modified="2008-04-29" version="1">MKNYISIFEIPAADISRAIEFYQAILNISIEKINMPDMEMGLFPYEEQVVTGVIVKVESFQPSAEGVTIYLNGGDNLQVILDKVVKHGGKTIVSKTAHADESGYFAIFHDSEGNRIGLHSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI30</accession>
    <name>B1KI30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1215"/>
    <dbReference type="EnsemblBacteria" id="ACA85508">
        <property type="protein sequence ID" value="ACA85508"/>
        <property type="gene ID" value="Swoo_1215"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1215"/>
    <dbReference type="eggNOG" id="ENOG5032RP9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126543_0_0_6"/>
    <dbReference type="OMA" id="LAYNARY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021279">
        <property type="entry name" value="DUF2721"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11026">
        <property type="entry name" value="DUF2721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14572" checksum="2B6FDD7913F70082" modified="2008-04-29" version="1" precursor="true">MLENIHVSLTTPALLFPAISLLLLAYTNRFFSLAALIRNLSSSGKPIESKQLKNLRQRISIIRRMQESGVMSFALCVLCMIFIYIGFNKVGSFIFGCSLLLLLYSLLLSVIEIRISVVALNYHLEEMDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI40</accession>
    <name>B1KI40_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323864.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1225"/>
    <dbReference type="EnsemblBacteria" id="ACA85518">
        <property type="protein sequence ID" value="ACA85518"/>
        <property type="gene ID" value="Swoo_1225"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1225"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055425_1_0_6"/>
    <dbReference type="OMA" id="GFTYGLC"/>
    <dbReference type="OrthoDB" id="1539551at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="174"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="355" mass="40271" checksum="076FE7EE7A9C018A" modified="2008-04-29" version="1" precursor="true">MRARIQAKKLIFAIIAWGIAMAAFVFFRYAQAPDLPQWAIGSADLATLAIYMGIIFGSLHWMSNLIADFSAINRLPYLFSVIFKGLFLLLGATTLAYITQFLNMWAIENHMATLRQMLTAHILYSPSFQALIVYLVVVRVGLAFIEQMALLVGPRVLLNIGLGKYHKPRYEQRLFLYLDMVASTTHAETLGDYRFSRLIQDSFSLLSDTVVNNEAEIYRYMGDAVLIHWPLKDGIQQDRCFNIYFEFSQQLNWQRQYFEEQYGFVPKFKAAAHCGQVVAAVVGVQKQEISFFSDVLNTLARLQDQCNPLGQRMLISGSLESRLDNDSSQYTLTNLGPVKLKGKQHSIEVFGVSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI50</accession>
    <name>B1KI50_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">L-aspartate oxidase</fullName>
            <ecNumber evidence="4 11">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_1236</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the oxidation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323874.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1236"/>
    <dbReference type="EnsemblBacteria" id="ACA85528">
        <property type="protein sequence ID" value="ACA85528"/>
        <property type="gene ID" value="Swoo_1236"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1236"/>
    <dbReference type="eggNOG" id="COG0029">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_3_0_6"/>
    <dbReference type="OMA" id="HCVQWLI"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00551">
        <property type="entry name" value="nadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0274">FAD</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="14">
        <location>
            <begin position="10"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="15">
        <location>
            <begin position="443"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA85528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="536" mass="59706" checksum="791626CD2CB37A64" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIG0</accession>
    <name>B1KIG0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tol-pal system-associated acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325348.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2735"/>
    <dbReference type="EnsemblBacteria" id="ACA87011">
        <property type="protein sequence ID" value="ACA87011"/>
        <property type="gene ID" value="Swoo_2735"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2735"/>
    <dbReference type="eggNOG" id="COG0824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101141_7_1_6"/>
    <dbReference type="OMA" id="YHASYLR"/>
    <dbReference type="OrthoDB" id="1786865at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014166">
        <property type="entry name" value="Tol-Pal_acyl-CoA_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006684">
        <property type="entry name" value="YbgC/YbaW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003230">
        <property type="entry name" value="YbgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02799">
        <property type="entry name" value="thio_ybgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00051">
        <property type="entry name" value="TIGR00051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="2">
        <location>
            <begin position="16"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="132" mass="15229" checksum="513AA69B8FC33DFA" modified="2008-04-29" version="1">MFRWPISVYYEDTDAGGVVYHSNYLNFFERARTEWLKAIGVKQTVLLAEDIAFVVKRAELDFCRAARFEQDLFVETLVIEMKRASLTFQQRLVDQQGVVYCEGKINVACITLSRMKPRAIPQNIVQELKSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII0</accession>
    <name>B1KII0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326804.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4220"/>
    <dbReference type="EnsemblBacteria" id="ACA88476">
        <property type="protein sequence ID" value="ACA88476"/>
        <property type="gene ID" value="Swoo_4220"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4220"/>
    <dbReference type="eggNOG" id="COG3242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179416_0_2_6"/>
    <dbReference type="OMA" id="APNGWRN"/>
    <dbReference type="OrthoDB" id="2079765at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019201">
        <property type="entry name" value="DUF2065"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38602">
        <property type="entry name" value="PTHR38602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09838">
        <property type="entry name" value="DUF2065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="62" mass="6837" checksum="9A25316DFE0BE832" modified="2008-04-29" version="1">MSLQLIMLALGIVLIIEGIGPFLFPNRWKAYLKEISNQNQQLLQRLGGALVTAGVVLLIIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII2</accession>
    <name>B1KII2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rplM</name>
        <name evidence="7" type="ordered locus">Swoo_4222</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326805.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4222"/>
    <dbReference type="EnsemblBacteria" id="ACA88478">
        <property type="protein sequence ID" value="ACA88478"/>
        <property type="gene ID" value="Swoo_4222"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4222"/>
    <dbReference type="eggNOG" id="COG0102">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082184_2_2_6"/>
    <dbReference type="OMA" id="DFVVIIN"/>
    <dbReference type="OrthoDB" id="1822215at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_L13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="15932" checksum="B90D6D8EC5544AB0" modified="2008-04-29" version="1">MKTTFTATPETVTREWFVVDAEGKTLGRIATEIATRLRGKHKPEYTPHVDTGDYIIVINAEKVAVTGNKAKGKVYYSHSGFIGGIKQITFEKLQDHKPEMIIEKAVKGMLPKGPLGRAMFRKLKVYAGTEHNHAAQQPQVLDI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIS4</accession>
    <name>TAL_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transaldolase</fullName>
            <ecNumber evidence="2">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tal</name>
        <name type="ordered locus">Swoo_1280</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323918.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIS4"/>
    <dbReference type="SMR" id="B1KIS4"/>
    <dbReference type="STRING" id="392500.Swoo_1280"/>
    <dbReference type="EnsemblBacteria" id="ACA85572">
        <property type="protein sequence ID" value="ACA85572"/>
        <property type="gene ID" value="Swoo_1280"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1280"/>
    <dbReference type="eggNOG" id="COG0176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047470_0_1_6"/>
    <dbReference type="OMA" id="KFGYKTL"/>
    <dbReference type="OrthoDB" id="784333at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00492">
        <property type="entry name" value="Transaldolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="PTHR10683:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0570">Pentose shunt</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0704">Schiff base</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000126257" description="Transaldolase">
        <location>
            <begin position="1"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00492"/>
        </source>
    </evidence>
    <sequence length="318" mass="35107" checksum="7700BA9E1995115E" modified="2008-04-29" version="1">MANTLEQFKSITTIVADTGDIEAIKRYQPEDATTNPSLILKAAQIPDYAHLIENAIEWAKTQSSQIDQQVEDAGDKLAVNIGVEILKIVPGRISTEVDARLSFDKAGSIAKAHKLIKLYQEAGIDKSRILIKLASTWEGICAAKELEQEGINCNLTLLFSFAQARACAEAGVYLISPFVGRILDWYKKDTGLEYSATEDPGVVSVTEIYNYYKRHGFNTVVMGASFRNTGEIIELAGCDRLTIGPALLEEMANSQTEVVRKLIPAETTVEAGEPLTEAQFRWEFNENPMAVEKLAEGIRNFAIDQGKLEVMLKEKLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY6</accession>
    <name>B1KIY6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323980.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1342"/>
    <dbReference type="EnsemblBacteria" id="ACA85634">
        <property type="protein sequence ID" value="ACA85634"/>
        <property type="gene ID" value="Swoo_1342"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1342"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_35_0_6"/>
    <dbReference type="OMA" id="ECLIAED"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="32731" checksum="C12C9D1BEFA98789" modified="2008-04-29" version="1">MSTIEQLTSFITTVESGSFSAAARKLGKVQSAVSQNIMNMEIDTGLVLFDRSGRYPVLTPKGRQLLPQAKAVIAQHRRLTQQVSALESEETKKLTLAIDEGIPYAHLIELLPQLEHAHPELELEFLCASSQDVIQLVLDKRATTGLVFSDNLYPESIDFETLGTVEFELLISPKHPLAQTDSPHMDMLKLHRQLVISSKGSKTTWFNQAHSPDVWHADNYYVLLELAKSGFGWTLLPLHLAKEALEANTLCRVPVQFEQLGWQANVDVIQESSMISEANHTLRALLRRLLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ38</accession>
    <name>B1KJ38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325394.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87058">
        <property type="protein sequence ID" value="ACA87058"/>
        <property type="gene ID" value="Swoo_2782"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2782"/>
    <dbReference type="HOGENOM" id="CLU_2261916_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767393" evidence="1">
        <location>
            <begin position="21"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="103" mass="11601" checksum="451337F8860AB539" modified="2008-04-29" version="1" precursor="true">MKKLSLVCCLLFLTACSANNVNKNNDTYNNTDLDSLVLPSHYTSPCFRKNKKIYNEFSTLLGRLEIGELSQSDAASKMVVLCPHQPEMIIWLTNTFAKPPAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA1</accession>
    <name>B1KJA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326899.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4320"/>
    <dbReference type="EnsemblBacteria" id="ACA88573">
        <property type="protein sequence ID" value="ACA88573"/>
        <property type="gene ID" value="Swoo_4320"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4320"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085376_1_4_6"/>
    <dbReference type="OMA" id="AGRFEWY"/>
    <dbReference type="OrthoDB" id="1069752at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="19824" checksum="6A7F710AB696BBC6" modified="2008-04-29" version="1">MANPINEGIKRLRAQHKLTQIELAEMAGIPRATLANMESSNSNPSISVVMKVAQALGVTVDDLITQRQSVHVTKVERKDMPVSHQDEGKFISTRTSPISTQNLQISDVIMMPGCNTKGVPHPEGSHELFLCLDGTATLEVQGELFEIEAGNLTYFKGHLPHQYGNASLKPVHAIVVVFMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG0</accession>
    <name>B1KJG0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycoside hydrolase family 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326958.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4380"/>
    <dbReference type="CAZy" id="GH17">
        <property type="family name" value="Glycoside Hydrolase Family 17"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88632">
        <property type="protein sequence ID" value="ACA88632"/>
        <property type="gene ID" value="Swoo_4380"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4380"/>
    <dbReference type="eggNOG" id="COG5309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_825656_0_0_6"/>
    <dbReference type="OMA" id="LEPEKHW"/>
    <dbReference type="OrthoDB" id="926333at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="321" mass="36460" checksum="EB65FB25B5A293A5" modified="2008-04-29" version="1">MNLTPGNAICYSGYREGQNPGTGHYPSFDEVKEDLTILSQNWTYLRLYDCGPHAEIVLDVIQKEGFAFKVMLGADLGAEMSNPNCPWDANFDAETLQKNQANNLAQINKLIALSKQYSDTIFSVSIGNEASVEWTDHLVSVESLIGYVRMIKKEISQPVTFCENYVPWTNKLAPLVAELDFLSIHTYPVWEYQTIETALEYTKQNYYSVANMYPDTPVCITEAGWACASNGRGIEPWNASQELQAIYYEQLMEWTTQAQILTFVFEAFDEQWKGSSHPLEPEKHWGLFNLDRTPKLVMKSLYQQLNQASQQDGSVIIQNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI9</accession>
    <name>B1KJI9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase, short-chain dehydrogenase/reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324008.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1370"/>
    <dbReference type="EnsemblBacteria" id="ACA85662">
        <property type="protein sequence ID" value="ACA85662"/>
        <property type="gene ID" value="Swoo_1370"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1370"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_7_6"/>
    <dbReference type="OMA" id="THCTITA"/>
    <dbReference type="OrthoDB" id="968232at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="27032" checksum="8FECCFEA54FACDA8" modified="2008-04-29" version="1">MITQQTLIIGASSDIAVAIAIQVEKIDSTGLVLVTRDFSAYSEIIDDNINKILIEDYQSASIEAVIRQLAQLDHAPITQVFICHGVLHTQQIKPEKRLEDLTAASFEQVMMINALTPILWLQKLTPLLTSSIPCKITVFSARVGSISDNRLGGWYSYRASKAALNMMLKTAAIELARRAKNIKIIAFHPGTTDTALSKPFQKNVPPGKLFSCEFVAKQLLEIVEKSELDSTLSYLDWQGKAISW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJK4</accession>
    <name>RISB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="1">DMRL synthase</shortName>
            <shortName evidence="1">LS</shortName>
            <shortName evidence="1">Lumazine synthase</shortName>
            <ecNumber evidence="1">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ribH</name>
        <name type="ordered locus">Swoo_1385</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324023.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJK4"/>
    <dbReference type="SMR" id="B1KJK4"/>
    <dbReference type="STRING" id="392500.Swoo_1385"/>
    <dbReference type="EnsemblBacteria" id="ACA85677">
        <property type="protein sequence ID" value="ACA85677"/>
        <property type="gene ID" value="Swoo_1385"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1385"/>
    <dbReference type="eggNOG" id="COG0054">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089358_1_1_6"/>
    <dbReference type="OMA" id="CQGVTQG"/>
    <dbReference type="OrthoDB" id="1680292at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000098229" description="6,7-dimethyl-8-ribityllumazine synthase">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="81"/>
            <end position="83"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <sequence length="160" mass="16877" checksum="FB25AB0FF9D2C94C" modified="2008-04-29" version="1">MNVVQGNIESKNAKVAIVVSRFNSFVVESLLEGAVDTLKRFGQVADENITVIRVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQVALEFDLPVSFGVLTTDTIEQAIERSGTKAGNKGGEAALGLLEMVNVLQELEQQLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ6</accession>
    <name>B1KJZ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sua5/YciO/YrdC/YwlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2910"/>
    <dbReference type="EnsemblBacteria" id="ACA87183">
        <property type="protein sequence ID" value="ACA87183"/>
        <property type="gene ID" value="Swoo_2910"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2910"/>
    <dbReference type="eggNOG" id="COG0009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031397_3_0_6"/>
    <dbReference type="OMA" id="MLYPTDT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="21"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="23757" checksum="73F44AD0548818C0" modified="2008-04-29" version="1">MVMDGIEMSQFFYVHEENPQARLINQAVNAIKNGGVIVYPTDSGYALGCLLGEKDAMSRIARIRQIDNDHNFSLMCRDQSELSTYAKVDNQAYRVLKHNTPGPYTFIFKASKEVPKRLQNPKKKTIGIRVPDNVIALALLEALDEPLMSTSLILPGEEFTESDPEHIRDILEHQVDVIIHGGYLGEKPTTVIDLSEGDIEIIREGAGDISSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK46</accession>
    <name>B1KK46_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327003.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4425"/>
    <dbReference type="EnsemblBacteria" id="ACA88677">
        <property type="protein sequence ID" value="ACA88677"/>
        <property type="gene ID" value="Swoo_4425"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4425"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055632_0_0_6"/>
    <dbReference type="OMA" id="DANPKAF"/>
    <dbReference type="OrthoDB" id="1704967at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767416" evidence="1">
        <location>
            <begin position="28"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="26976" checksum="9616E53CC60FA2AC" modified="2008-04-29" version="1" precursor="true">MAKIAKVMTLFIFVLGSFTFVNRDAHAQITHVSINQKLFSLGEYPKFRLNIVSESGNYSKMQFVVQQGGSEERLMVKPINKFLLLLTGVEDVVDPSARLVIREYRVNKWRDVKRFELFSGDEQHVTPRVKKKVLESEIKRVESRLVELQGAGALNDGACQLSTLPGQTLWRIATQYSKEWGMSPQGGAVAIYEANPQAFSAESISSLRADSKLMCPSDLIKNKYKDPNVAQRTYKTLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK54</accession>
    <name>B1KK54_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3859 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327011.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4433"/>
    <dbReference type="EnsemblBacteria" id="ACA88685">
        <property type="protein sequence ID" value="ACA88685"/>
        <property type="gene ID" value="Swoo_4433"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4433"/>
    <dbReference type="eggNOG" id="ENOG50323IW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1833331_0_0_6"/>
    <dbReference type="OMA" id="CIYHPDI"/>
    <dbReference type="OrthoDB" id="1740180at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024331">
        <property type="entry name" value="DUF3859"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12975">
        <property type="entry name" value="DUF3859"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3859" evidence="1">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="18205" checksum="81922EB54A161289" modified="2008-04-29" version="1">MSKLKFDVNIIYSGIFTKWNEQSDSLPRLTKATVHVPAEVDIEFGFIAQIKKAKNQKLRYCIYHPDIPDDDGEIRPPFDGELYVESNDWKFYIGDTIWAPIQNKTGKWRMTLELKGKVIAEKTFKVHLPDELPHSDTNLLKHENEKIASFWKKRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKA8</accession>
    <name>B1KKA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Proprotein convertase P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4488</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327065.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4488"/>
    <dbReference type="MEROPS" id="S08.125"/>
    <dbReference type="EnsemblBacteria" id="ACA88739">
        <property type="protein sequence ID" value="ACA88739"/>
        <property type="gene ID" value="Swoo_4488"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4488"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019254_0_0_6"/>
    <dbReference type="OMA" id="PFMTDVI"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764601" evidence="6">
        <location>
            <begin position="24"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="7">
        <location>
            <begin position="437"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="592" mass="62393" checksum="BFAD9616E569694F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI1</accession>
    <name>B1KKI1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1533"/>
    <dbReference type="EnsemblBacteria" id="ACA85821">
        <property type="protein sequence ID" value="ACA85821"/>
        <property type="gene ID" value="Swoo_1533"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1533"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_548456_0_0_6"/>
    <dbReference type="OMA" id="AYWLLKY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="478" mass="53825" checksum="AC827ED567E0AB93" modified="2008-04-29" version="1" precursor="true">MPKMLNNFFIFVSFLYILESHAQFSLEQIPEIENKKAITLVAETGFWTVHLKEKMLPKFTAQTGIKVNVITTSLDQMYTLQTESLIQGAGKYDLLTMEAGWAKEWASKGLTVPLSELASLYDPSGERGINSYLEPYYSSLLNILSYQGEIHAIPYNNYVMGNHYRADLFEHPKEKFNFQAKYGYTLAPPSSIQELKDISAFFTREAGENLGSNILKKPFYGLALMSGNRPHINDEFSSILWSLNGYWMKPEYNGKEKIKLFQLPRENATLIRTANIYRDLMRHAFPAHKQFAFKEAANTLANGDVAMWPFAYNNLWSASFQVESNIPGAKLGIAQVPGGKPYNGAYAFAVAYDSVNPQAAYWLLKYMGSFEAQYAYALGGGNPCRIDVATAPEFQTEELRHIGGAFNVSHNANINWSDEVLKLGHFTSTAMGDIYPELAKSCFQLSNSNEDIESVTSQLINKIEQIQNRSGEVPVVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL72</accession>
    <name>B1KL72_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
            <ecNumber evidence="3">3.5.1.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.32" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322762.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0112"/>
    <dbReference type="EnsemblBacteria" id="ACA84413">
        <property type="protein sequence ID" value="ACA84413"/>
        <property type="gene ID" value="Swoo_0112"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0112"/>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_1_1_6"/>
    <dbReference type="OMA" id="NKGMMHA"/>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047980">
        <property type="term" value="F:hippurate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="178"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="384" mass="41397" checksum="6A39F704DE5E2929" modified="2008-04-29" version="1">MNIEQKVIEWRHHIHQHPEFGTQEHETAAFVASKLEEFGIEVHTGIGGTGVVGILKCGDSERSIGLRADMDALHIHEENTFDYASVNEGAMHACGHDGHTAMLLAAAHELAQTKNFDGTVYFIFQPDEERGTGAKAMIADGLFTRWKIDGVYAMHNLPGIEAGHFVTRPHSVMASESSFEIEVLATGGHAAMPHMGTDPIVVGAQIVTAIQTIVSRNLSAIDETAVISVTEFATNGTVNVIPTKVTITGDTRSFTDGALNKIEKALERVVAGQCMSAGVDYTYKFNNSFLSTINTPAETAFAVRAAQTVVGEDKVNGSCQPFTISEDFSFMLREAPGCYILVGNGAGCGCGSVALHKPTYDFNDNILVSGLRYWQTLVEQCLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL84</accession>
    <name>B1KL84_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oligopeptidase A</fullName>
            <ecNumber evidence="8">3.4.24.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0124</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).</text>
            <dbReference type="EC" id="3.4.24.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.70" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322774.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0124"/>
    <dbReference type="MEROPS" id="M03.004"/>
    <dbReference type="EnsemblBacteria" id="ACA84425">
        <property type="protein sequence ID" value="ACA84425"/>
        <property type="gene ID" value="Swoo_0124"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0124"/>
    <dbReference type="eggNOG" id="COG0339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001805_4_1_6"/>
    <dbReference type="OMA" id="KNFQSAM"/>
    <dbReference type="OrthoDB" id="1935578at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045666">
        <property type="entry name" value="OpdA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19310">
        <property type="entry name" value="TOP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TOP_N" evidence="11">
        <location>
            <begin position="31"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="10">
        <location>
            <begin position="222"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA84425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="679" mass="76780" checksum="4B2FAE6DCC515E5F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL90</accession>
    <name>B1KL90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0130"/>
    <dbReference type="EnsemblBacteria" id="ACA84431">
        <property type="protein sequence ID" value="ACA84431"/>
        <property type="gene ID" value="Swoo_0130"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0130"/>
    <dbReference type="eggNOG" id="ENOG502Z93K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074587_1_0_6"/>
    <dbReference type="OMA" id="GWGHWNL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010239">
        <property type="entry name" value="CHP02001"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09694">
        <property type="entry name" value="Gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02001">
        <property type="entry name" value="gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767174" evidence="1">
        <location>
            <begin position="29"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="27409" checksum="CEF7225FEA9E3DE3" modified="2008-04-29" version="1" precursor="true">MTIKMTLQHKLLLSGLLLSAASVTQVQAEENNQVLGGTINGNLTFASDYVFRGESETLDGDVPVVQGTLGWGNDDGWYGGVFASNIKFADPNLEIVTAPFIGKAGEFGDSGITYDVMVFSYLYPGASYSNYTELWLKVGKQFGQANIQLEVTPTIDDWFGVDGWQGVNYAIHPSYEFSNGVNLSGSVGYQDLDGEGAEGWGHWNLGISKTYAGLKFDLRYHGSTVDETHKVYGTQTEIFDDRFVIGVSKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL91</accession>
    <name>B1KL91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0131</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322781.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0131"/>
    <dbReference type="EnsemblBacteria" id="ACA84432">
        <property type="protein sequence ID" value="ACA84432"/>
        <property type="gene ID" value="Swoo_0131"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0131"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_2_1_6"/>
    <dbReference type="OMA" id="INVRYTK"/>
    <dbReference type="OrthoDB" id="1579676at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="64"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="383" mass="40689" checksum="982D71103332EF3E" modified="2008-04-29" version="1">MRQIVKIASVISVALWITGCDQKPEGSGTAAGPQSVPVNVIKVATQPQEITLELPGRSRAYLEAEVRPQVSGIVLARSFNEGGEVKKGQSLYQIDASQYEAALVSAKAELERAQAAEKSTKATAKRFSSLIKSKSISQQDFDTAEANYLEAKASVAVAKAAINTAEINLAYTKVESPISGRIGKSNVTAGALVGAGQAQALANISQLDPINVDIVQSSTQMLRLKQRIASGQLLNDNTAPVALFLEDGSRYSHKGKLQFAEVTVNENTGAVVLRAEFPNPDGLLLPGMFVRTVLTVGTDPEAILVPQKAVTRNPKGQGVAMVVNAENKVEPRIVETAEVINHQWLITKGLEAGDQLIVEGLQKIRPGAPVTPQLISEAKAQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD1</accession>
    <name>B1KLD1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324202.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1570"/>
    <dbReference type="EnsemblBacteria" id="ACA85856">
        <property type="protein sequence ID" value="ACA85856"/>
        <property type="gene ID" value="Swoo_1570"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1570"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_0_6"/>
    <dbReference type="OMA" id="IRGRWNI"/>
    <dbReference type="OrthoDB" id="1200399at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="58"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="375" mass="40991" checksum="9C1928FC2542C450" modified="2008-04-29" version="1" precursor="true">MNIITDILQNKIIMAMLLIGLLSACQGEVTTHSTQAQLQTVTTQSLTLSNSYQHTQEFTGTIRAGNTTGIGFELSGKLKSLAVDSGDSVEKGQLLAQLDTRLLEAERAEIDASLSQNSADLTLARNTLNRSLELQKQGYTSEQQLDELKGQLNSLLAAQKRLTASKLANALRIEKSSLLAPFSGVISKRNSNLGEVVALGTPIFTLVQNRNPQAFVGVPVKLAQQLNTKQGVLLKVGNNSYTAQIEGKGAEVNPVTRTVPLRLSLPIDAQVINGEIAYLIYETDIQQNGYWVPISALTDGIRGLWNLYVITPNNDLEADKGTFNIERRDIEILYTKEDMAYIQGALKVNEDYITQGLHKLVVGQQVKRNTNVAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI3</accession>
    <name>B1KLI3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar FliJ protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1622</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324254.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1622"/>
    <dbReference type="EnsemblBacteria" id="ACA85908">
        <property type="protein sequence ID" value="ACA85908"/>
        <property type="gene ID" value="Swoo_1622"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1622"/>
    <dbReference type="eggNOG" id="COG2882">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119965_3_2_6"/>
    <dbReference type="OMA" id="KRDQKLM"/>
    <dbReference type="OrthoDB" id="2042666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018006">
        <property type="entry name" value="Flag_FliJ_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012823">
        <property type="entry name" value="Flagell_FliJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02050">
        <property type="entry name" value="FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019404">
        <property type="entry name" value="FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01004">
        <property type="entry name" value="FLGFLIJ"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02473">
        <property type="entry name" value="flagell_FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="17705" checksum="FC5FBFFC9105142E" modified="2008-04-29" version="1">MAKHDPLDTVLKLAKEAEEQAGLQLKSAQLMLQKCQSQLEALRNYRLDYMKQMENHHGKNISASYYHQFHQFVRQIDEAITKQISSIQEADSQREHRQKYWQEMQQKRKAVELLLSHKADKAQQAELRREQKMTDEFASQLFYRKRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLR2</accession>
    <name>B1KLR2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Primosomal replication protein N'', putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325695.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3088"/>
    <dbReference type="EnsemblBacteria" id="ACA87359">
        <property type="protein sequence ID" value="ACA87359"/>
        <property type="gene ID" value="Swoo_3088"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3088"/>
    <dbReference type="eggNOG" id="COG3923">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1244631_0_0_6"/>
    <dbReference type="OMA" id="MQNSHQL"/>
    <dbReference type="OrthoDB" id="2011382at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038338">
        <property type="entry name" value="PriB/PriC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010890">
        <property type="entry name" value="Primosomal_replicat_PriB/PriC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07445">
        <property type="entry name" value="PriC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="26311" checksum="5BDA38FF4BA65427" modified="2008-04-29" version="1">MTTSELLKRLRAQHKQLEQEVLQHDAKLPKGQRRLLQDTERFNDSLFIQTGAELKPCIDQISKSIEQLEKLIKGKISANTILLSCERIQDRFTAVKRALATTSLDVKSAEHQKQMRIAKAQQRRRKSHSNSGFDWIAAGVMQNSHQLYEELNKHLNWVKAFEQKIQNLQSELEYCHSADKIKKQNEILLVHRRLGKCRQAISYIEERIQAFERPHTHTYRSFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM76</accession>
    <name>B1KM76_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322838.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0188"/>
    <dbReference type="EnsemblBacteria" id="ACA84489">
        <property type="protein sequence ID" value="ACA84489"/>
        <property type="gene ID" value="Swoo_0188"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0188"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069623_2_0_6"/>
    <dbReference type="OMA" id="GGMMTKP"/>
    <dbReference type="OrthoDB" id="1864858at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="10"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="145"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="264" mass="28971" checksum="3977489577115B35" modified="2008-04-29" version="1">MKVNQYVHGQPCWIELASRDAHAGKQFYSTLFDWKVQDMPIPNGVYSMLALEVEGECSDIGAAYQMPETMSEQGAPTTWTVYFAVDNVDATVAAVISNGGNLELGPHDVGTAGRMALLSDPEGARFAIWQAGDHIGAKRHGENGSLCWVELASRDGQDAKTFYSSSLGWDSRQDPMPDFTYTEWLVEDVPFGGMMEMTEEWGEMPAHWMLYFAVEDCDKTAEMATSLGGQICVPPTNIPEVGRFSVISDPQGGFFSVITLNSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM87</accession>
    <name>B1KM87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322849.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0199"/>
    <dbReference type="EnsemblBacteria" id="ACA84500">
        <property type="protein sequence ID" value="ACA84500"/>
        <property type="gene ID" value="Swoo_0199"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0199"/>
    <dbReference type="eggNOG" id="COG3776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159241_1_0_6"/>
    <dbReference type="OMA" id="MTFIVTI"/>
    <dbReference type="OrthoDB" id="2029461at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009525">
        <property type="entry name" value="DUF1145"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38775">
        <property type="entry name" value="PTHR38775"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06611">
        <property type="entry name" value="DUF1145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="90" mass="10333" checksum="3236B2BB54B60A91" modified="2008-04-29" version="1">MTFIVTIGKGITLLAWVLMGYNLVMPFNGEISLILNTLLLLTLVMHSIQILIFHRLFKTQLPLTRSDYLNVFAFGVFSLLAYRREVIEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMA8</accession>
    <name>B1KMA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaH subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322870.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0220"/>
    <dbReference type="EnsemblBacteria" id="ACA84521">
        <property type="protein sequence ID" value="ACA84521"/>
        <property type="gene ID" value="Swoo_0220"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0220"/>
    <dbReference type="eggNOG" id="COG3460">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141459_2_0_6"/>
    <dbReference type="OMA" id="PYRHPTF"/>
    <dbReference type="OrthoDB" id="2083684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009359">
        <property type="entry name" value="PaaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038693">
        <property type="entry name" value="PaaB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06243">
        <property type="entry name" value="PaaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030200">
        <property type="entry name" value="PaaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02157">
        <property type="entry name" value="PA_CoA_Oxy2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11509" checksum="21C18AC0B5406C94" modified="2008-04-29" version="1">MSNSSSFYQTSELYEVFIRSARGLEHKHIGSLHAESAEQAITYARDVYIRRSEGLSIWVVKSSDVHSSQESDIAHFYDPMDDKPYRHAQFVQLPDAIKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME4</accession>
    <name>B1KME4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324288.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1656"/>
    <dbReference type="EnsemblBacteria" id="ACA85942">
        <property type="protein sequence ID" value="ACA85942"/>
        <property type="gene ID" value="Swoo_1656"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1656"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_42_0_6"/>
    <dbReference type="OMA" id="GFPTKFV"/>
    <dbReference type="OrthoDB" id="1763624at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="391" mass="44479" checksum="BE64D0836A200A68" modified="2008-04-29" version="1">MKKLIYIGGFELPDKNAAAQRVIANSKIFSMLGYSLELIGVDKNLSFDDGLCSVSYSGCEFESKAVSYPKTNREWINTILGHDEIVNYLKENATDIECVILYNYPSIASFKIYSAMKQCNVTVISDITEWHSSRGAGLIFSIVKWLDTTLRIRYLAKKAGKVITTSQYMTDYYKSKNVETLELPTLYDTRKFTTPPKTLEKSSTSLIYIGNPFDVKRAAKAKGAVKERLDIVIKALSILSDNYVFTFNVYGISEEDYLTVYPEHIDLIKGLSDRVFFNGKMDHSFVIQRLQESDFSVFFRDETLVNLAGFPSKLAESVSCGIPVISSHIASLTKYQDISGVYLAQLGKEVDMIERCLKMTELELNELKEKTYNSKFFDCRMYFEQVKLFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMT5</accession>
    <name>B1KMT5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3192</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325799.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3192"/>
    <dbReference type="EnsemblBacteria" id="ACA87463">
        <property type="protein sequence ID" value="ACA87463"/>
        <property type="gene ID" value="Swoo_3192"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3192"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_2_0_6"/>
    <dbReference type="OMA" id="HRTESSY"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="14124" checksum="4D0960BE028D57D5" modified="2008-04-29" version="1">MKIGEVSKLTGLSVKSIRYYHDIGLVTALRGENGYREYEQPQLDSLKFINHCRELGFSLEDCRSLLQLKQNNLRDAEDVKSLAKAHLKQVSGRIIKLQTLEAQLTNLVKSCHGGQQPDCAILKGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMT8</accession>
    <name>B1KMT8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325802.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3196"/>
    <dbReference type="EnsemblBacteria" id="ACA87466">
        <property type="protein sequence ID" value="ACA87466"/>
        <property type="gene ID" value="Swoo_3196"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3196"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_6"/>
    <dbReference type="OMA" id="NYQTCYN"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="26867" checksum="6804CA496FFDBAA5" modified="2008-04-29" version="1" precursor="true">MDLKDKVVVITGGAGGLGLAMALDLAEAGAKLALIDVDQEKLERACADIGDRTEVQGYAFDITDEEDVMAGFGFIMEDFGKVNVLINNAGILYDGMLVKAKEGKVTSRMSFEQFQAVINVNLTGSFLCGREAAAAMIESEQEGVIINISSLAKAGNVGQTNYSASKAGVAAMSVGWAKELARYNIRSAAVAPGVIETEMTAAMKPEALERMEKMVPVGRLGQPREISSTVKFIIENDYVNGRVFEIDGGIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMU5</accession>
    <name>B1KMU5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87473">
        <property type="protein sequence ID" value="ACA87473"/>
        <property type="gene ID" value="Swoo_3203"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3203"/>
    <dbReference type="HOGENOM" id="CLU_2182163_0_0_6"/>
    <dbReference type="OMA" id="WYLMEAK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="12514" checksum="6BA06FAF85C65D74" modified="2008-04-29" version="1">MSELITAVWPILCLSMFPLAVWYLMEAKSVLNLLKSEHPQIWLELGNIQLVKNNTISNSYKFMVYILKADYRLLKGDKLSRKGNLLRRLLISGHLIAVFVFIAPIVIGR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN03</accession>
    <name>TRMA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA/tmRNA (uracil-C(5))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
            <ecNumber evidence="1">2.1.1.35</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (uracil(54)-C(5))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m5U54)-methyltransferase</fullName>
            <shortName evidence="1">RUMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tmRNA (uracil(341)-C(5))-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmA</name>
        <name type="ordered locus">Swoo_4710</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-adenosyl-L-methionine + uridine(54) in tRNA = 5-methyluridine(54) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42712"/>
            <dbReference type="Rhea" id="RHEA-COMP:10167"/>
            <dbReference type="Rhea" id="RHEA-COMP:10193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-adenosyl-L-methionine + uridine(341) in tmRNA = 5-methyluridine(341) in tmRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43612"/>
            <dbReference type="Rhea" id="RHEA-COMP:10630"/>
            <dbReference type="Rhea" id="RHEA-COMP:10631"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EC" id="2.1.1.35" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327278.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KN03"/>
    <dbReference type="SMR" id="B1KN03"/>
    <dbReference type="STRING" id="392500.Swoo_4710"/>
    <dbReference type="EnsemblBacteria" id="ACA88960">
        <property type="protein sequence ID" value="ACA88960"/>
        <property type="gene ID" value="Swoo_4710"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4710"/>
    <dbReference type="eggNOG" id="COG2265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043022_0_0_6"/>
    <dbReference type="OMA" id="DHMESGV"/>
    <dbReference type="OrthoDB" id="1421660at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030697">
        <property type="term" value="F:S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01011">
        <property type="entry name" value="RNA_methyltr_TrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011869">
        <property type="entry name" value="TrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47790">
        <property type="entry name" value="PTHR47790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02143">
        <property type="entry name" value="trmA_only"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000198558" description="tRNA/tmRNA (uracil-C(5))-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01011"/>
        </source>
    </evidence>
    <sequence length="365" mass="42317" checksum="7E83871CA75A1B0D" modified="2008-04-29" version="1">MNLAAMDPNTYDAQLEEKRIKLENIFTDFDTPNLEVFSSEQAHYRMRAEFRIWHDGEDMYYYMFDKALNSKVRCDQFLPASKLINEMMPALIAELKPNPLLRHRLFQIDFLSTLSGEILVSLLYHKQLDEQWETEAKSLKERLASKFNVNIIGRARKQKLIFDKDFVVESLQVNGEQLQYHQIENSFTQPNGKVSVKMLEWAIDVTKNSSGDLLELYCGNGNFSIALAQNFDRVLATELAKPSVESAQYNIKINKIDNLQIIRMSAEDFTDAMAKKRSFRRLEGIDLDSYNCNTIFVDPPRAGMDPDTVKLVQGYERIVYISCNPNTLIDNLVELSKTHKITRFALFDQFPYTDHMESGVFLERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN10</accession>
    <name>B1KN10_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'(2'),5'-bisphosphate nucleotidase CysQ</fullName>
            <ecNumber evidence="1">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">3'-phosphoadenosine 5'-phosphate phosphatase</fullName>
            <shortName evidence="1">PAP phosphatase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysQ</name>
        <name evidence="2" type="ordered locus">Swoo_4717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Converts adenosine-3',5'-bisphosphate (PAP) to AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily. CysQ family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327285.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4717"/>
    <dbReference type="EnsemblBacteria" id="ACA88967">
        <property type="protein sequence ID" value="ACA88967"/>
        <property type="gene ID" value="Swoo_4717"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4717"/>
    <dbReference type="eggNOG" id="COG1218">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_3_0_6"/>
    <dbReference type="OMA" id="SADCYPR"/>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02095">
        <property type="entry name" value="CysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006240">
        <property type="entry name" value="CysQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01331">
        <property type="entry name" value="bisphos_cysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="29887" checksum="475EF520D91ED71F" modified="2008-04-29" version="1">MKPEDYVEQAIEIAMVAGKKIRDIYLKGTFEKETKSDNTPVTSADIAAHNIITSALQSLTPDIPVLSEEDADIPFSTRQHWDRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPIMGIVYVPMTEVCYYAIAGLGAYKRDERSEVRIMSHQLPQSKDPALKLAVSRRQDPKSVLKLFSHSKHCDLIVLGGAALKSCLIAEGKADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDISLQPLTYNERESLENPNFIVVGSPQLEWDQILINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN25</accession>
    <name>B1KN25_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">General secretion pathway protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Swoo_4732</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 15">Cell inner membrane</location>
            <topology evidence="3 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327299.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4732"/>
    <dbReference type="EnsemblBacteria" id="ACA88982">
        <property type="protein sequence ID" value="ACA88982"/>
        <property type="gene ID" value="Swoo_4732"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4732"/>
    <dbReference type="eggNOG" id="COG1459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035032_0_1_6"/>
    <dbReference type="OMA" id="VAEQCEK"/>
    <dbReference type="OrthoDB" id="1596769at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011850">
        <property type="entry name" value="T2SS_GspF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001992">
        <property type="entry name" value="T2SS_GspF/T4SS_PilC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02120">
        <property type="entry name" value="GspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00874">
        <property type="entry name" value="T2SP_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="17">
        <location>
            <begin position="73"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="17">
        <location>
            <begin position="275"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACA88982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="407" mass="44746" checksum="A61411DC3A7F487C" modified="2008-04-29" version="1">MPAFEYKALDNKGKQQKGVMEADTARHARGQLRELRLMPLEIVPVVEKETKAKTGGKSLFQRGISVAELALITRQIATLVAAGLPVEEALKAVGQQCEKDRLASMIMAVRSRVVEGYNLADSMAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTERRQQLKSKMTQAMIYPVVLTVVAISVIAILLAAVVPQVVGQFEHMGQELPWTTLLLIASSDFIRDYGIIILGAAFALFVLFKRMLTKPEFRMKYDSLLLTLPVIGRVSKGLNTARFARTLSILTASSVPLLDAMRIASEVLVNVKVRAAVEEATARVREGTSLGAALTNTKLFPPMMLYMITSGEKSGQLEQMLERAADNQDREFESNVNIALGVFEPLLVVSMAAVVLFIVLAILQPILELNNMISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ2</accession>
    <name>B1KNQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325846.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3240"/>
    <dbReference type="EnsemblBacteria" id="ACA87510">
        <property type="protein sequence ID" value="ACA87510"/>
        <property type="gene ID" value="Swoo_3240"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3240"/>
    <dbReference type="eggNOG" id="ENOG50331V8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142248_0_0_6"/>
    <dbReference type="OMA" id="GCAGEYT"/>
    <dbReference type="OrthoDB" id="1709849at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030852">
        <property type="entry name" value="RcsF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16358">
        <property type="entry name" value="RcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765082" evidence="1">
        <location>
            <begin position="20"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="13502" checksum="47B5D52421263AA0" modified="2008-04-29" version="1" precursor="true">MKKLLFPALVIFLSGCAGEYTFNSNLNGEAIDDYFKASDVAVYENGLPKGQFEPIGLVEGESCQIGENDAPASIVEARTIARRKAADKGANGLIIKTCFVSPEQTQQCVSSAICIGQAVNIANTQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNR1</accession>
    <name>B1KNR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III restriction protein res subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325855.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3249"/>
    <dbReference type="EnsemblBacteria" id="ACA87519">
        <property type="protein sequence ID" value="ACA87519"/>
        <property type="gene ID" value="Swoo_3249"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3249"/>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012831_0_0_6"/>
    <dbReference type="OMA" id="DLCPHQD"/>
    <dbReference type="OrthoDB" id="840727at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="671"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="698"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="18"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="884" mass="100604" checksum="03A88A1AF57A0EED" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP40</accession>
    <name>B1KP40_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pirin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4822</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327388.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4822"/>
    <dbReference type="EnsemblBacteria" id="ACA89071">
        <property type="protein sequence ID" value="ACA89071"/>
        <property type="gene ID" value="Swoo_4822"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4822"/>
    <dbReference type="eggNOG" id="COG1741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1213997_0_0_6"/>
    <dbReference type="OMA" id="FSHNEIN"/>
    <dbReference type="OrthoDB" id="729805at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="PTHR43212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="56"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA89071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="24772" checksum="7068296292DE06C8" modified="2008-04-29" version="1">MEKLSKVDLREGGFAGLKEHRFVMDSRVFGRGKEPKTWDGVGHFVYLADARFMPKGETMMHGHREVDVISVMVKGQIAHEGSLEHGQSIVAKQVQVQRAGGEGFSHNEINPDDVENQMIQLWVMPETLGERADYRLYSPVDGELTPIYGGAAQTFNSRTQVSVANLNSGDEIALPTPALIYVSDGSVTLANETVSAGTLVRSTQAQLDTKLTAVEESQVIVVSLLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP44</accession>
    <name>B1KP44_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable chorismate pyruvate-lyase</fullName>
            <shortName evidence="1">CL</shortName>
            <shortName evidence="1">CPL</shortName>
            <ecNumber evidence="1">4.1.3.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiC</name>
        <name evidence="2" type="ordered locus">Swoo_4826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = 4-hydroxybenzoate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:16505"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="EC" id="4.1.3.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.40" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327392.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4826"/>
    <dbReference type="EnsemblBacteria" id="ACA89075">
        <property type="protein sequence ID" value="ACA89075"/>
        <property type="gene ID" value="Swoo_4826"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4826"/>
    <dbReference type="eggNOG" id="COG3161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096824_1_1_6"/>
    <dbReference type="OMA" id="ELWGRRS"/>
    <dbReference type="OrthoDB" id="1274776at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008813">
        <property type="term" value="F:chorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042866">
        <property type="term" value="P:pyruvate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01632">
        <property type="entry name" value="UbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007440">
        <property type="entry name" value="Chorismate--pyruvate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38683">
        <property type="entry name" value="PTHR38683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04345">
        <property type="entry name" value="Chor_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="21237" checksum="06D06EBF04F9D6F2" modified="2008-04-29" version="1">MSVIRLSFPYGESIQWFSPEKIDQLPKSPLKDWLLSKGSLTQKLRSHCAEFEVKVLGEGTLTPFSGEFPSQSQAWVREVLLCLDGIPWVFARTLIPGSLLQQKESDFLTLGTRPLGELLFSSDEFSPGRIEVAHFTPCHKLANLMRSLKQDANHELWGRRRYFSYHEEELIVSETFLPAAQQLIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP49</accession>
    <name>B1KP49_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327397.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4831"/>
    <dbReference type="EnsemblBacteria" id="ACA89080">
        <property type="protein sequence ID" value="ACA89080"/>
        <property type="gene ID" value="Swoo_4831"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4831"/>
    <dbReference type="eggNOG" id="COG4319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132147_0_0_6"/>
    <dbReference type="OMA" id="WVITHDH"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764709" description="DUF4440 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4440" evidence="2">
        <location>
            <begin position="25"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="16028" checksum="4E166DE77199DD1B" modified="2008-04-29" version="1" precursor="true">MFKKGLSLILLLVAFSASAVPTDDIAQVLKAQEAAWNRGDLDAYMQGYWNNEKMRFVSGDKFRYGWEETLAAYKRNYPDKATLGTLKFTIKEIKMLSNYGAMVVGRWQLTRAKDKPSGVFTLLVEKIDDRWVITHDHTSD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP58</accession>
    <name>HUTI_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Imidazolonepropionase</fullName>
            <ecNumber evidence="1">3.5.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Imidazolone-5-propionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hutI</name>
        <name type="ordered locus">Swoo_4840</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23660"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="3.5.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc or iron ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. HutI family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327406.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP58"/>
    <dbReference type="SMR" id="B1KP58"/>
    <dbReference type="STRING" id="392500.Swoo_4840"/>
    <dbReference type="EnsemblBacteria" id="ACA89089">
        <property type="protein sequence ID" value="ACA89089"/>
        <property type="gene ID" value="Swoo_4840"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4840"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041647_0_0_6"/>
    <dbReference type="OMA" id="CAPHARW"/>
    <dbReference type="OrthoDB" id="785930at2"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050480">
        <property type="term" value="F:imidazolonepropionase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01296">
        <property type="entry name" value="Imidazolone-5PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00372">
        <property type="entry name" value="HutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005920">
        <property type="entry name" value="HutI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42752">
        <property type="entry name" value="PTHR42752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01224">
        <property type="entry name" value="hutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0369">Histidine metabolism</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000121557" description="Imidazolonepropionase">
        <location>
            <begin position="1"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00372"/>
        </source>
    </evidence>
    <sequence length="408" mass="43926" checksum="7E4FD3A32416E7BD" modified="2008-04-29" version="1">MSWDQVWIDVNVASMDPSVSAPYGAIIDAALAVKDGKIAWVGPRGELPEFDVMSTPLYRGKGGWITPGLIDAHTHLVFAGNRANEFEKRLQGASYEEIARSGGGIISTVKACREASEAELFELGRKRLNALAKEGVTTVEIKSGYGLDTATELKLLRVARELGKHHHVDVKTTFLGAHAIPPEYKDDVEGYVDLVINEMLPAVIAEDLADAVDVFCENIAFNIEQTERVLTAAKDAGLDIKLHAEQLSNLGGSTMAAKLGAKSVDHIEYLDEDGVVALSKSGTCATLLPGAFYFLRETQMPPIDLLRKHKVPMVLASDYNPGSSPLCSSLLMLNMGCTLFRLTPEEALAGMTRNAAKALGVEDKVGVLAAGMQADFCLWDISTPAELAYSYGVGVCLEVVKDGHLVHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP90</accession>
    <name>B1KP90_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Signal peptidase I</fullName>
            <ecNumber evidence="3 6">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323009.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0360"/>
    <dbReference type="MEROPS" id="S26.026"/>
    <dbReference type="EnsemblBacteria" id="ACA84660">
        <property type="protein sequence ID" value="ACA84660"/>
        <property type="gene ID" value="Swoo_0360"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0360"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_1_2_6"/>
    <dbReference type="OMA" id="IEPRWIP"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S26" evidence="7">
        <location>
            <begin position="12"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="217" mass="24960" checksum="568F6F7FD465F787" modified="2008-04-29" version="1" precursor="true">MSKIKTFWKNNRQLFIFIILMSVFRSAVADWYTVPTGSMQPTIKEGDRIVVDKMAYDLRVPFTQISLLETGEPQRGEIIVFESKAAKNRLIKRVIGLPGDKISLSNEILSINGRPLNYTVLDNNSQELIAEEELTGLRHKIRIEKSASNNLSHFATITVPENHYMVMGDNRRNSVDSRVYGFVPRAELKGKATQIAFSLNYDNYYIPREDRFFSDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA4</accession>
    <name>B1KPA4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="5 8">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0375</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADP(+) + S-(hydroxymethyl)glutathione = H(+) + NADPH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="5 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323023.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0375"/>
    <dbReference type="EnsemblBacteria" id="ACA84674">
        <property type="protein sequence ID" value="ACA84674"/>
        <property type="gene ID" value="Swoo_0375"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0375"/>
    <dbReference type="eggNOG" id="COG1062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_14_0_6"/>
    <dbReference type="OMA" id="RVKMIAT"/>
    <dbReference type="OrthoDB" id="1859760at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106322">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NAD activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106321">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NADP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006069">
        <property type="term" value="P:ethanol oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N" evidence="10">
        <location>
            <begin position="33"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="9">
        <location>
            <begin position="202"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="40284" checksum="36ECBF3588060ADE" modified="2008-04-29" version="1">MTAQTIKSKAAVAWAVGEPLSMEIVDVMPPQKGEVRIKMIATGVCHTDAFTLSGDDPEGIFPCILGHEGGGIVESIGEGVTSVQVGDHVIPLYTPECGECKFCKSGKTNLCQKIRETQGKGLMPDGTTRFSKDGVDIFHYMGTSTFSEYTVLPEISLAKVNPEAPLEEVCLLGCGVTTGMGAVMNTAKVEEGSTVAIFGMGGIGLSAVIGATMAKAARIIVIDINESKFELARKLGATDCINPKDYDKPIQDVIVELTDGGVDYSFECIGNVHVMRSALECCHKGWGESVVIGVAGAGQEISTRPFQLVTGRVWKGSAFGGVKGRSELPEYVERYMAGEFKLNDFITHTMGLEQVNEAFDLMHEGKSIRTVIHFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE7</accession>
    <name>B1KPE7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0419</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323066.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0419"/>
    <dbReference type="EnsemblBacteria" id="ACA84717">
        <property type="protein sequence ID" value="ACA84717"/>
        <property type="gene ID" value="Swoo_0419"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0419"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_10_0_6"/>
    <dbReference type="OMA" id="FHGEKNT"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767534" evidence="3">
        <location>
            <begin position="27"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Ser)" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="513" mass="57639" checksum="3B0C8B5E17549ADE" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPJ8</accession>
    <name>B1KPJ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">8-amino-7-oxononanoate synthase</fullName>
            <ecNumber evidence="4">2.3.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1867</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324497.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1867"/>
    <dbReference type="EnsemblBacteria" id="ACA86151">
        <property type="protein sequence ID" value="ACA86151"/>
        <property type="gene ID" value="Swoo_1867"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1867"/>
    <dbReference type="eggNOG" id="COG0156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_11_2_6"/>
    <dbReference type="OMA" id="HYHASGI"/>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="59"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="400" mass="42656" checksum="9AF2171795736CEE" modified="2008-04-29" version="1">MTNKSLDALSCDRVSLSQKIEIRQAQLKEAGLLRQREKLSVTRGGSDKPAMLFSVEGVDYLNFSSNDYLGLSQSSELVEALNLSANDYGVGSGSSPLVTGYSQAHQQLEQRLCQITGHEAGLLFCSGFSANTALMKTLFDASDNVVADKLIHASIIDGLGDSKARLKRFLHNDLQSAERLLLKYQPQALVTESIFSMDGDRAPLQALSELCHQHEAWLIVDDAHGFGIDAALANKACAVNASLVDIQVVTFGKALGCQGAAILGSQALIDFLVANAREYIYSTALSPTSASLALAAVNLTQTSIQPAMTLADNIAYFRQSCATAQLNLSGSVTPIQPLIIGDADRTLKVAADLKNSGVWVGAIRPPTVPKGSARLRITITALHTRSDIDKLVSALVLALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPR3</accession>
    <name>B1KPR3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3327</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325932.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3327"/>
    <dbReference type="EnsemblBacteria" id="ACA87596">
        <property type="protein sequence ID" value="ACA87596"/>
        <property type="gene ID" value="Swoo_3327"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3327"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007487_0_1_6"/>
    <dbReference type="OMA" id="LAWVNKY"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="58"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="4">
        <location>
            <begin position="216"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="531"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="4">
        <location>
            <begin position="681"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="944" mass="104185" checksum="7C50244416102B7E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS3</accession>
    <name>B1KPS3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Probable oxaloacetate decarboxylase gamma chain</fullName>
            <ecNumber evidence="12">7.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">oadG</name>
        <name evidence="14" type="ordered locus">Swoo_3337</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12 13">Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:57724"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="EC" id="7.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12 13">
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7 12">Heterotrimer of an alpha, a beta and a gamma subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 12 13">Cell membrane</location>
            <topology evidence="4 12 13">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 12 13">Belongs to the OadG family.</text>
    </comment>
    <dbReference type="EC" id="7.2.4.2" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325941.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3337"/>
    <dbReference type="EnsemblBacteria" id="ACA87606">
        <property type="protein sequence ID" value="ACA87606"/>
        <property type="gene ID" value="Swoo_3337"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3337"/>
    <dbReference type="eggNOG" id="COG3630">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168750_2_0_6"/>
    <dbReference type="OMA" id="YLVQLMS"/>
    <dbReference type="OrthoDB" id="2053060at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015451">
        <property type="term" value="F:decarboxylation-driven active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00404">
        <property type="entry name" value="OadG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005899">
        <property type="entry name" value="Na_pump_deCOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023424">
        <property type="entry name" value="OadG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04277">
        <property type="entry name" value="OAD_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01195">
        <property type="entry name" value="oadG_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0915">Sodium</keyword>
    <keyword evidence="12 13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="9 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12 13">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="81" mass="8703" checksum="08B9DA3DCDC52603" modified="2008-04-29" version="1">MNSISEQIVESFGIMLLGMGLVFVFLTVLILGVKLVAWRFAPLPITPKTPAENGSATQNQGVDPKMVAVITAAIEQYRAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPV1</accession>
    <name>B1KPV1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325969.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3365"/>
    <dbReference type="EnsemblBacteria" id="ACA87634">
        <property type="protein sequence ID" value="ACA87634"/>
        <property type="gene ID" value="Swoo_3365"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3365"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_3_1_6"/>
    <dbReference type="OMA" id="EAYELTF"/>
    <dbReference type="OrthoDB" id="1626703at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="18066" checksum="9CE32A6724E5052E" modified="2008-04-29" version="1">MVKNSSTLKINDAELTNDNQQSQSLSDNVCFALYTAGNALVRAYRPLLEQCDLTYPQYLVMQALWLNDGASLTDLSRETRLDLGTLTPIVKRLEAKSLLVRRIDSQDERKKVIQVTPSGIALKQEALSLKQVLLSKVSISEQEIDSLRDLCLTLIDDLNQK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ10</accession>
    <name>GPDA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="1">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gpsA</name>
        <name type="ordered locus">Swoo_4874</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327440.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ10"/>
    <dbReference type="SMR" id="B1KQ10"/>
    <dbReference type="STRING" id="392500.Swoo_4874"/>
    <dbReference type="EnsemblBacteria" id="ACA89123">
        <property type="protein sequence ID" value="ACA89123"/>
        <property type="gene ID" value="Swoo_4874"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4874"/>
    <dbReference type="eggNOG" id="COG0240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033449_0_2_6"/>
    <dbReference type="OMA" id="NRMFGNM"/>
    <dbReference type="OrthoDB" id="1419877at2"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000123189" description="Glycerol-3-phosphate dehydrogenase [NAD(P)+]">
        <location>
            <begin position="1"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00394"/>
        </source>
    </evidence>
    <sequence length="339" mass="36118" checksum="291E461547B0FCFF" modified="2008-04-29" version="1">MKNTADITVLGAGSYGTALAISLASNGHRTLLWGHDPEHIENLKRDRANEAFLPGITLPDLLVPEADLATALAASNNVLVVVPSHVFGLVLEQAKPLLREDSRIVWATKGLEPETGRLLQEVAREVLGDKYPLAVLSGPTFAKELAAGMPTAISVAGTDESFTQDLVELLHSSNRLRVYANDDFTGLQLGGAVKNVIAISAGMSDGIGFGANARTALITRGLVELTRLGEAIGAQASTFMGMAGLGDLVLTCTDNQSRNRRFGLALGKGQGVEEAQVEIGQVVEGYRNTKEVYTLAKRLGVEMPITEQVYKVLYQGGTPHEAAKSLLAREKKSETEDSE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ31</accession>
    <name>GLMU_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="1">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="1">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">glmU</name>
        <name type="ordered locus">Swoo_4895</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="1"/>
    <dbReference type="EC" id="2.3.1.157" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327461.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ31"/>
    <dbReference type="SMR" id="B1KQ31"/>
    <dbReference type="STRING" id="392500.Swoo_4895"/>
    <dbReference type="EnsemblBacteria" id="ACA89144">
        <property type="protein sequence ID" value="ACA89144"/>
        <property type="gene ID" value="Swoo_4895"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4895"/>
    <dbReference type="eggNOG" id="COG1207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_15_2_6"/>
    <dbReference type="OMA" id="TAIVEHK"/>
    <dbReference type="OrthoDB" id="1381953at2"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00533"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000186490" description="Bifunctional protein GlmU">
        <location>
            <begin position="1"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="248"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="8"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="383"/>
            <end position="384"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <sequence length="454" mass="47981" checksum="BB1C7DFA24825102" modified="2008-04-29" version="1">MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHNVGSDAIQLVYGYGGEKLQSVLGEQQLNWVLQAEQLGTGHAVAQANSNIADDDTVLILYGDVPLIQASTLEALLAAREENGLAILTVNLPNPTGYGRIVREANKVVGIIEQKDANAEQLAINEINTGIMAAPGKQLKAWLGQLSSNNAQGEYYLTDIVAMAHRDGVAITTAQPDSAIEVEGANNRVQLAQLERAYQARAAEKLMLEGANLRDPARIDIRGEVSVGMDVMIDVNVIMQGKVTIGNNVTIGAGAILIDCEISDNAEIKPYSIVESAKVGAEASAGPFARLRPGAELKRDAHIGNFVEMKKAVLGEGSKAGHLAYIGDAQIGSGVNIGAGTITCNYDGANKHLTVIEDNVFVGSDTQLVAPVTIGKGATLGAGSTITKDVAADELVITRVKQRHLTGWPRPVKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ49</accession>
    <name>B1KQ49_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4913</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327478.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4913"/>
    <dbReference type="EnsemblBacteria" id="ACA89162">
        <property type="protein sequence ID" value="ACA89162"/>
        <property type="gene ID" value="Swoo_4913"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4913"/>
    <dbReference type="eggNOG" id="COG1115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024867_1_1_6"/>
    <dbReference type="OMA" id="HYREKNE"/>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA89162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="48622" checksum="6F8DBF0F35D82ECE" modified="2008-04-29" version="1">MTLASISAEFADLAWGPHMLVLLVGGGLFFILYSRFIPFRYLGHAVAIVRGKHPDKGAVGHISHAGALSSAMAGTVGMGNIGSVAVAIVVGGPGAIFWMWISAIVGMATKFFTCTLAIMYRGKDENGQVQGGPMYIITQGLGKKWHFLAVFFCVVGLVGNFPLFNTNQLVQILKEWLIIKPGFYGEDQPTFWLDLSMGIVVMFLVASVILGGIKRIASVASSVVPTMILLYMSCAFYVIATHIEEIPGYFSLIVEQAFSLNSVGGGILGTMLIGIRRAAFSNEAGIGTEVMAHGSAKTSEPVKEGLVAMLGPAIDTLLVCSATAMIILISGVWQTTDVSGVSLSARAFESTMPGVGPYLLIVCVFFFSISTIFTQAFYGGQCFSFLFGAKRVKYYQYFFLLAILFAATATLDEIVNIIDGAYALMAIPTMVSALLLAPKVKAAADDYFARLNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ59</accession>
    <name>B1KQ59_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Catalase-related peroxidase</fullName>
            <ecNumber evidence="1">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4923</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has an organic peroxide-dependent peroxidase activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327488.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4923"/>
    <dbReference type="EnsemblBacteria" id="ACA89172">
        <property type="protein sequence ID" value="ACA89172"/>
        <property type="gene ID" value="Swoo_4923"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4923"/>
    <dbReference type="eggNOG" id="COG0753">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045961_2_0_6"/>
    <dbReference type="OMA" id="KINHTKG"/>
    <dbReference type="OrthoDB" id="1584770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08153">
        <property type="entry name" value="srpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024168">
        <property type="entry name" value="Catalase_SrpA-type_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="PTHR11465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000296">
        <property type="entry name" value="SrpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0349">Heme</keyword>
    <keyword evidence="1 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764745" description="Catalase-related peroxidase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase" evidence="5">
        <location>
            <begin position="37"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="3">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000296-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000296-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA89172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="330" mass="36472" checksum="046E2964DBCF03D6" modified="2008-04-29" version="1" precursor="true">MDSYRLVSFINTCLLTGVTVLSSSVFAADRSSAELVDAVNGTPDSASREAGKKVKLRNHAKGFCTSGSFIPNPKLHNTLAIPFFKQAEIPITARFSLGGTNPHASDRGAGRFMSLKIDGDKESLNFVTTNSPVFFASNLEEFFNFQTKVKQGAEGKQWLVDNQPNAKAFFDYIKTLPPSASFANSRYFGVNSFLFSANNGDIKPGRWSFEPVDGVVNLSQNQLDKLPNNFLKDELLTLIQQKPAIWDLYIQLAEPGDEINDPTVLWPETRQRLLVGQVLIDGSRDSESATMQCDRGIFNPVLLPEGIKPSADPILNARTPAYIESFIRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ63</accession>
    <name>B1KQ63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327492.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4927"/>
    <dbReference type="EnsemblBacteria" id="ACA89176">
        <property type="protein sequence ID" value="ACA89176"/>
        <property type="gene ID" value="Swoo_4927"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4927"/>
    <dbReference type="eggNOG" id="COG1643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_5_6_6"/>
    <dbReference type="OMA" id="HERRWDT"/>
    <dbReference type="OrthoDB" id="604268at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="22"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="227"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="838" mass="92781" checksum="3A72D6EF4F4E1A1E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC9</accession>
    <name>B1KQC9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="3">DAP decarboxylase</shortName>
            <shortName evidence="3">DAPDC</shortName>
            <ecNumber evidence="3 4">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysA</name>
        <name evidence="7" type="ordered locus">Swoo_0486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="3 4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323133.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0486"/>
    <dbReference type="EnsemblBacteria" id="ACA84784">
        <property type="protein sequence ID" value="ACA84784"/>
        <property type="gene ID" value="Swoo_0486"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0486"/>
    <dbReference type="eggNOG" id="COG0019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026444_0_0_6"/>
    <dbReference type="OMA" id="YCRSMAS"/>
    <dbReference type="OrthoDB" id="861683at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="6">
        <location>
            <begin position="35"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="5">
        <location>
            <begin position="281"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="3">
        <location>
            <begin position="273"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="414" mass="45400" checksum="711D2EDD83C79A38" modified="2008-04-29" version="1">MDHFLYKNGELLAEDCQVAELARTYGTPLYIYSRATLERHWHAFDSAVANHPHLICYAVKANSNIAVLNVLARLGSGFDIVSGGELSRVIEAGGDPKKVVFSGVGKTVEEMEMALNLGIHCFNVESAAELEQLNLVALKLGKIAPVSLRVNPDVDAGTHPYISTGLKENKFGIAMDDAEAIFARAHALPGLQVKGVDCHIGSQLTEIKPFLDAMDRILALIDRLAEQDIIIEHFDVGGGLGVTYDDETPPQPDVYASALVERLGDRKLKLIFEPGRAIAANAGIFVTQVLYLKGNSDKHFALVDGAMNDLIRPSLYSAWQKIIPVVPREGESRNYDIVGPVCETGDFLGKERELCLEPQDYLAVRSSGAYGFTMSSNYNSRPRAAEVMVDGEQAHLIRQREKLSQLWQGEQLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQW9</accession>
    <name>B1KQW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326060.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3458"/>
    <dbReference type="EnsemblBacteria" id="ACA87725">
        <property type="protein sequence ID" value="ACA87725"/>
        <property type="gene ID" value="Swoo_3458"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3458"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025058_1_0_6"/>
    <dbReference type="OMA" id="WDYIPKV"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="387"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="518" mass="60044" checksum="92B3C4E223CA5C24" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR05</accession>
    <name>UBIB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable protein kinase UbiB</fullName>
            <ecNumber evidence="1">2.7.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ubiquinone biosynthesis protein UbiB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiB</name>
        <name type="ordered locus">Swoo_0525</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text>Cofactor biosynthesis; ubiquinone biosynthesis [regulation].</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC1 family. UbiB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323170.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KR05"/>
    <dbReference type="SMR" id="B1KR05"/>
    <dbReference type="STRING" id="392500.Swoo_0525"/>
    <dbReference type="EnsemblBacteria" id="ACA84822">
        <property type="protein sequence ID" value="ACA84822"/>
        <property type="gene ID" value="Swoo_0525"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0525"/>
    <dbReference type="eggNOG" id="COG0661">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_0_0_6"/>
    <dbReference type="OMA" id="RRDYKRV"/>
    <dbReference type="OrthoDB" id="678616at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010795">
        <property type="term" value="P:regulation of ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13972">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00414">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010232">
        <property type="entry name" value="UbiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045308">
        <property type="entry name" value="UbiB_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01982">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="chain" id="PRO_1000123928" description="Probable protein kinase UbiB">
        <location>
            <begin position="1"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="123"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="129"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00414"/>
        </source>
    </evidence>
    <sequence length="549" mass="63339" checksum="3022D174DADF8F3E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRC3</accession>
    <name>B1KRC3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324676.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2046"/>
    <dbReference type="EnsemblBacteria" id="ACA86330">
        <property type="protein sequence ID" value="ACA86330"/>
        <property type="gene ID" value="Swoo_2046"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2046"/>
    <dbReference type="eggNOG" id="COG1607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050164_3_0_6"/>
    <dbReference type="OMA" id="KWIDQAG"/>
    <dbReference type="OrthoDB" id="1712258at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17342" checksum="B08C7E80EA6712D0" modified="2008-04-29" version="1">MAGIERQVTLRFLAEPADVNFGGKVHGGAVMKWIDLAAYACAAAWSGKYCITAYAGGIRFVKPIHVGNIVETSAKVIYTGRTSMHLGIDVRAGDPKHPERHLTTHCIVIMVAVDDDGNPSEVPEWCPVDEKDIELRDSAIRLMEMRKKIGAEMEAHVQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRC5</accession>
    <name>CDD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytidine deaminase</fullName>
            <ecNumber evidence="1">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytidine aminohydrolase</fullName>
            <shortName evidence="1">CDA</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cdd</name>
        <name type="ordered locus">Swoo_2048</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324678.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRC5"/>
    <dbReference type="SMR" id="B1KRC5"/>
    <dbReference type="STRING" id="392500.Swoo_2048"/>
    <dbReference type="EnsemblBacteria" id="ACA86332">
        <property type="protein sequence ID" value="ACA86332"/>
        <property type="gene ID" value="Swoo_2048"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2048"/>
    <dbReference type="eggNOG" id="COG0295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052424_0_0_6"/>
    <dbReference type="OMA" id="NYSPCGH"/>
    <dbReference type="OrthoDB" id="959039at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047844">
        <property type="term" value="F:deoxycytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01558">
        <property type="entry name" value="Cyt_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013171">
        <property type="entry name" value="Cyd/dCyd_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020797">
        <property type="entry name" value="Cytidine_deaminase_bacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08211">
        <property type="entry name" value="dCMP_cyt_deam_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000147116" description="Cytidine deaminase">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="CMP/dCMP-type deaminase 1" evidence="2">
        <location>
            <begin position="47"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="CMP/dCMP-type deaminase 2" evidence="2">
        <location>
            <begin position="186"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01083"/>
        </source>
    </evidence>
    <sequence length="296" mass="32135" checksum="EC081977C092FB3B" modified="2008-04-29" version="1">MQDRFIKCIAQLPKPLSDALIPLLNADFAGHIDAQQLGMLTTKSQLEESELLLALLPIAAALAKPPISEFYVGAIAKGKSGDIYMGANLELSGEALFHSVHAEQSAISHAWLSGETQILDVVVNFSPCGHCRQFMNEMVEGQKVVIHLPEQKAQPLAHYLPYAFGPSNLNITEPLLSKQQHELSLDSSDPMIIEALDHASLSYAPYSNSYAAVVLETKDGATYCGRYAENAAFNPSMLPMQMALSTMTRHNREFTEINRAVLIESAQGKISLVGATMDALHAVAAVELEHIVIDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRE4</accession>
    <name>B1KRE4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ordered locus">Swoo_2067</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324696.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2067"/>
    <dbReference type="EnsemblBacteria" id="ACA86351">
        <property type="protein sequence ID" value="ACA86351"/>
        <property type="gene ID" value="Swoo_2067"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2067"/>
    <dbReference type="eggNOG" id="COG0072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016891_0_0_6"/>
    <dbReference type="OMA" id="ISYNWLK"/>
    <dbReference type="OrthoDB" id="53568at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14 19" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="39"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="401"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="701"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACA86351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="795" mass="86962" checksum="0C7FAE20EF119847" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRL6</accession>
    <name>B1KRL6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis protein UbiV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiV</name>
        <name evidence="2" type="ordered locus">Swoo_3517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms an heterodimer with UbiU.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U32 family. UbiV subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326114.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3517"/>
    <dbReference type="EnsemblBacteria" id="ACA87781">
        <property type="protein sequence ID" value="ACA87781"/>
        <property type="gene ID" value="Swoo_3517"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3517"/>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056172_0_0_6"/>
    <dbReference type="OMA" id="CCIKYPT"/>
    <dbReference type="OrthoDB" id="1725274at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02233">
        <property type="entry name" value="UbiV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043693">
        <property type="entry name" value="UbiV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="286" mass="32115" checksum="BB4ADE233583959A" modified="2008-04-29" version="1">MKASLGPILYCWPKEKVIEFYTQVAASQIPLVYLGETICSRRRELKFSDYMDLAHMLRDSGKEVVLSTLALLEAPSEYTELKKQVENGEFIIEANDMGAIQAAKENKLPFICGPTINNYNLASLKTLHKWGMQRFVMPVELSKHWLNTVVSVEKPEFEIEIFGHGFLPLALSARCFTARQKGLVKDKCQTICIENPKGLLAQTQESQPLLRLNGIQTQSAACIDLTSELSSMSDMGISYFRVSPSSVSCIEKADKLFELGSQSVQVDDTHCNGYWHQQAGFNHLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRM2</accession>
    <name>B1KRM2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Xanthine/uracil/vitamin C permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326120.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3523"/>
    <dbReference type="EnsemblBacteria" id="ACA87787">
        <property type="protein sequence ID" value="ACA87787"/>
        <property type="gene ID" value="Swoo_3523"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3523"/>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024508_0_1_6"/>
    <dbReference type="OMA" id="WVLTNLP"/>
    <dbReference type="OrthoDB" id="558559at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="458" mass="47277" checksum="9D1BD87FB8EBCB60" modified="2008-04-29" version="1">MQSQQTSPTPEVSAIQSSGLLSFLDRFFTISQRGSTLKREAIAGLTTFLAMVYSVIVVPNMLGAAGFDTGAVFIATCLIAAFGSLLMGLWANLPMAIGCAISLTAFTAFSMVLGQGISIPVTLGAIFLMGVVFTFVSVTGIRQWVLTNLPKGIAHGTGIGIGLFLLLIATNSVQLIVANDAGLPVKLGDINSLPVLAAIIGLAATIGLEKRGVPGGILLVIIALSLFGLFFDPSVQYQGFFAWPNLMSEQSLIGQLDIMGALNPVVLPIVLALVMTAIFDATGTIRAVAGQAELLDEKDNIVGGGKALTSDSVSSIVAGAVGGAPAAVYIESAAGTAAGGKTGLTATIVGVLFLLMMFLAPLSYLVPAYATAPALMYVGLLMLSNVTKLDFNDKVDAMAGLTCAVFIILSCNIVTGIMLGFVTLVIGRICSGEWRQLKPGVVAITLGLVVFYMGGWAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRR9</accession>
    <name>B1KRR9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326167.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3570"/>
    <dbReference type="EnsemblBacteria" id="ACA87834">
        <property type="protein sequence ID" value="ACA87834"/>
        <property type="gene ID" value="Swoo_3570"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3570"/>
    <dbReference type="eggNOG" id="COG1534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095994_2_0_6"/>
    <dbReference type="OMA" id="FQVGKNG"/>
    <dbReference type="OrthoDB" id="2034603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001890">
        <property type="entry name" value="RNA-binding_CRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017924">
        <property type="entry name" value="RNA-binding_YhbY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035920">
        <property type="entry name" value="YhbY-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01985">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01103">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75471">
        <property type="entry name" value="SSF75471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00253">
        <property type="entry name" value="RNA_bind_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51295">
        <property type="entry name" value="CRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="10862" checksum="94F02CA97EC6001B" modified="2008-04-29" version="1">MNLTTKQKQHLKGLAHNLKPVVMLGSNGLTEGVLAEIDNALAYHELIKVKVASGDRELKNAVVDAIVRETQAVKVQLIGHVLVLFRQSEEMKIAIPKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRS7</accession>
    <name>B1KRS7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="6">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">carA</name>
        <name evidence="8" type="ordered locus">Swoo_3578</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326175.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3578"/>
    <dbReference type="EnsemblBacteria" id="ACA87842">
        <property type="protein sequence ID" value="ACA87842"/>
        <property type="gene ID" value="Swoo_3578"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3578"/>
    <dbReference type="eggNOG" id="COG0505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035901_2_1_6"/>
    <dbReference type="OMA" id="CFNTGMT"/>
    <dbReference type="OrthoDB" id="662268at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="7">
        <location>
            <begin position="3"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="381" mass="41125" checksum="7D54D96D66968E89" modified="2008-04-29" version="1">MTKSALLVLEDGTVFSGIAIGADGHAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNTGTNDEDTESDSVHACGLIIRDLPLIASNFRNQQSLSDYLKANNIVGIADIDTRKLTRILREKGAQAGCILVGEQDVEKALAEAKAFPGLKGMDLAKEVTTDTQYQWRNGSWRLVGGLPDDSPESDLKYKVVAYDYGVKRNILRMLVDRGCDVTVVPAQTPASEVLAMNPDGIFLSNGPGDPEPCDYAIAAIQEILKTDIPVFGICLGHQLLALASGAKTLKMKFGHHGANHPVSNIEQGNVMITSQNHGFAADETSLPANIKVTHKSLFDGSLQGIHLTDKPAFSFQGHPEASPGPNDAAPLFNHFIELIELYRQNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCV8</accession>
    <name>B1KCV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322682.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0032"/>
    <dbReference type="EnsemblBacteria" id="ACA84333">
        <property type="protein sequence ID" value="ACA84333"/>
        <property type="gene ID" value="Swoo_0032"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0032"/>
    <dbReference type="eggNOG" id="ENOG5031FBD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2411567_0_0_6"/>
    <dbReference type="OMA" id="MIVIDHA"/>
    <dbReference type="OrthoDB" id="2098473at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="92" mass="10519" checksum="8C449C7954D88F18" modified="2008-04-29" version="1">MVVLDEEHMSWILFQNTNDMYLSVVCGTVGMFTVEIQLTNSEATSYKLTGKSYIDQFASSICAKPDYFTPRKVANFKTKFNVTEALSEWRNS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX1</accession>
    <name>HEM6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Oxygen-dependent coproporphyrinogen-III oxidase</fullName>
            <shortName evidence="1">CPO</shortName>
            <shortName evidence="1">Coprogen oxidase</shortName>
            <shortName evidence="1">Coproporphyrinogenase</shortName>
            <ecNumber evidence="1">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hemF</name>
        <name type="ordered locus">Swoo_0045</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:18257"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="1.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322695.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCX1"/>
    <dbReference type="SMR" id="B1KCX1"/>
    <dbReference type="STRING" id="392500.Swoo_0045"/>
    <dbReference type="PRIDE" id="B1KCX1"/>
    <dbReference type="EnsemblBacteria" id="ACA84346">
        <property type="protein sequence ID" value="ACA84346"/>
        <property type="gene ID" value="Swoo_0045"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0045"/>
    <dbReference type="eggNOG" id="COG0408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026169_0_1_6"/>
    <dbReference type="OMA" id="HDKGTLF"/>
    <dbReference type="OrthoDB" id="1086432at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00333">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018375">
        <property type="entry name" value="Coprogen_oxidase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="PTHR10755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="SSF102886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01021">
        <property type="entry name" value="COPROGEN_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0350">Heme biosynthesis</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000119827" description="Oxygen-dependent coproporphyrinogen-III oxidase">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for dimerization" evidence="1">
        <location>
            <begin position="242"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="110"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for dimerization" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00333"/>
        </source>
    </evidence>
    <sequence length="306" mass="34945" checksum="B6F9FF863FC3D45F" modified="2008-04-29" version="1">MSVPDVSVVKAFLLDLQQRICDGLEQLDGEAKFKADSWKREEGGGGTSRVLTQGKVFEQAGVNFSHVTGAAMPASATAHRPELAGRSFEAMGVSLVIHPNNPYIPTTHANVRFFIAKKEGADPVWWFGGGFDLTPYYPFKEDVIEWHQNAHDLCLPFGEEVYPKYKKWCDDYFYLPHRDETRGVGGLFFDDLNAEGFDTSFAFMQAVGNGFLTAYAPIVQRRKETQYGEREREFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSMPPLVRWEYMYTPEENSPESLLYSDYLTPKDWLSLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD13</accession>
    <name>B1KD13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0059</name>
        <name evidence="3" type="ordered locus">Swoo_2161</name>
        <name evidence="4" type="ordered locus">Swoo_3334</name>
        <name evidence="5" type="ordered locus">Swoo_3467</name>
        <name evidence="6" type="ordered locus">Swoo_3827</name>
    </gene>
    <organism evidence="2 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908</strain>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0059"/>
    <dbReference type="EnsemblBacteria" id="ACA84360">
        <property type="protein sequence ID" value="ACA84360"/>
        <property type="gene ID" value="Swoo_0059"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86445">
        <property type="protein sequence ID" value="ACA86445"/>
        <property type="gene ID" value="Swoo_2161"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87603">
        <property type="protein sequence ID" value="ACA87603"/>
        <property type="gene ID" value="Swoo_3334"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87733">
        <property type="protein sequence ID" value="ACA87733"/>
        <property type="gene ID" value="Swoo_3467"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88086">
        <property type="protein sequence ID" value="ACA88086"/>
        <property type="gene ID" value="Swoo_3827"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0059"/>
    <dbReference type="KEGG" id="swd:Swoo_2161"/>
    <dbReference type="KEGG" id="swd:Swoo_3334"/>
    <dbReference type="KEGG" id="swd:Swoo_3467"/>
    <dbReference type="KEGG" id="swd:Swoo_3827"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2963">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139800_0_1_6"/>
    <dbReference type="OMA" id="IGWHIAS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="244"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="411" mass="47519" checksum="4C61ADFEE2725040" modified="2008-04-29" version="1">MTTQIPTHVKRTQRDYSLGFKLQVVAAVEKGDMTYKQAQSIYGIQGRSTVLTWLRKHGKMDWTQPVRITMPKTTKAKETPAQKIKRLEKELEDEHLRNLLLNEAVDIIDAEYGAGLRKKVLSQGARSLQKQKVTSLNRACELLGITRQAIYQRETRELCRAIELAPVKAMVLDIRRFMPRVGGRKLYFLLKPKFIEKGIKLGRDNFFSYLKREGLLVKPKHNYTKTTHSKHWMKKHPNLLKEFTPLSPEEVFVSDITYVQSEQGVHYLSLVTDAFSRKIMGYELSDEMKATDVVKALKMTVNNRQYQGHAVHHSDRGLQYCSAVYQSALQKNGIRASMTDGYDCYQNALAERVNGILKQEFLLYPCSNLDELKRLVEESVFIYNEMRPHLSLGMRTPNQVHKKDQQQEQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD52</accession>
    <name>B1KD52_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycine cleavage system regulatory protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3623</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326220.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3623"/>
    <dbReference type="EnsemblBacteria" id="ACA87887">
        <property type="protein sequence ID" value="ACA87887"/>
        <property type="gene ID" value="Swoo_3623"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3623"/>
    <dbReference type="eggNOG" id="COG2716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095322_2_0_6"/>
    <dbReference type="OMA" id="IEHMEFN"/>
    <dbReference type="OrthoDB" id="1859752at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="167" mass="18386" checksum="9B7C361C8D2E9B14" modified="2008-04-29" version="1">MKKLFIASVVGHIAPGVIKSLAEVTRRFDGEWVTSKVIKLDGHFCAMMKVAIKPEAEDELKSCLVSEFDGLHFIFEQVLVNSDSVSSSLHLSVDCGDRSGLTRDIVNILTNLDLVIEHMEFNRVHVSTIGQTVFSSRLNLAVPEGVSTESIVELLEGVTYDARVKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD89</accession>
    <name>B1KD89_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Galactokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3662</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3662"/>
    <dbReference type="EnsemblBacteria" id="ACA87924">
        <property type="protein sequence ID" value="ACA87924"/>
        <property type="gene ID" value="Swoo_3662"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3662"/>
    <dbReference type="eggNOG" id="COG0153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_2_1_6"/>
    <dbReference type="BRENDA" id="2.7.1.2">
        <property type="organism ID" value="12548"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalKase_gal_bdg" evidence="8">
        <location>
            <begin position="25"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_N" evidence="6">
        <location>
            <begin position="129"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="7">
        <location>
            <begin position="293"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="412" mass="45059" checksum="92F59309AC133BA3" modified="2008-04-29" version="1" precursor="true">MIRLAMASVGNLKEGFIVDLYKLFEQFESLFSRTVEGVSSAPGRVNLIGEFTDYNDGYVLPCALPFRTYVAYRKRSDNIIMAYSTNYPDECEAFELAPAISHGMSHWGNYIRAIAYVYKMAGYQLGGMDILISSNVPQGAGLSSSAALEVALGGAINQAFELDLTLEKIALLGQQAENYFLGCQCGIMDQLVSAKAIKNQALMIDCMSLAIEHFSVPEELALIVINSNFPRKLVESEYNQRRRDCMNAAAKMGVSTLRQASLSLLEESRALMTLNEYKRAHHVITENRRVLQAAKALQDNNLEVLSELMAESHTSLRDNFEVTVAVTDGLVDICHSALGADCATRMTGGGFGGAVICICRHGDVPKIVEAVSSQYNKYFGLQETIYVVNAAGGLMTTLGTSRSALVNEEFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD98</accession>
    <name>B1KD98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3671</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326266.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3671"/>
    <dbReference type="EnsemblBacteria" id="ACA87933">
        <property type="protein sequence ID" value="ACA87933"/>
        <property type="gene ID" value="Swoo_3671"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3671"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_6_1_6"/>
    <dbReference type="OMA" id="FGRTWPE"/>
    <dbReference type="OrthoDB" id="1930882at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="85"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="23923" checksum="F37BF86BCD2E9215" modified="2008-04-29" version="1">MPSTQAPHPLFSLKKNIIFYAVMLCMTLLSILFIDRHLADFIHQHEVANSFTKLLSNIPALLETLAAIALLCCLVPKLRSKLSALVIHLLFTLLLATVIRFGAKALFGRTWPETWVDNNPSWINDRIEAFHPFAEGVAYNSFPSGHALFTFALASTFWFHLPRYRLFWAACMLGVFIGQLSQNYHYLGDLLAGASLGVVCTQLAFTVAQKCHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA0</accession>
    <name>B1KDA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AbgT putative transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326268.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87935">
        <property type="protein sequence ID" value="ACA87935"/>
        <property type="gene ID" value="Swoo_3673"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3673"/>
    <dbReference type="eggNOG" id="COG2978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040132_0_0_6"/>
    <dbReference type="OMA" id="PLNNWFF"/>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015558">
        <property type="term" value="F:secondary active p-aminobenzoyl-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902604">
        <property type="term" value="P:p-aminobenzoyl-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004697">
        <property type="entry name" value="AbgT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30282">
        <property type="entry name" value="PTHR30282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03806">
        <property type="entry name" value="ABG_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="481"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="518" mass="55543" checksum="9A3377EC37282FAA" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA7</accession>
    <name>B1KDA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TadE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323256.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0612"/>
    <dbReference type="EnsemblBacteria" id="ACA84908">
        <property type="protein sequence ID" value="ACA84908"/>
        <property type="gene ID" value="Swoo_0612"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0612"/>
    <dbReference type="eggNOG" id="ENOG5033CBU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1651465_0_0_6"/>
    <dbReference type="OMA" id="REMIVVQ"/>
    <dbReference type="OrthoDB" id="1900099at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="19239" checksum="338D91B4BBC127A6" modified="2008-04-29" version="1" precursor="true">MQYKRLKRRQLGAFSVEFAIGAMVMFLVTFGIFEISRLIYVINLAESSLRESSRDTRVWEGERSGDLYDQRLTQMFEKKGEIWHLLVDPKRYHLSITYFESLSDLIDDKPSLSQAKQQRSPLAIYEISYQYTPMFFLAGIVEKKISRRILVTMEHEGWPIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDB5</accession>
    <name>B1KDB5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323264.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0620"/>
    <dbReference type="EnsemblBacteria" id="ACA84916">
        <property type="protein sequence ID" value="ACA84916"/>
        <property type="gene ID" value="Swoo_0620"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0620"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054750_2_0_6"/>
    <dbReference type="OMA" id="VLIHFMP"/>
    <dbReference type="OrthoDB" id="1274094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="25613" checksum="C2A3A5B24F6BDDC3" modified="2008-04-29" version="1" precursor="true">MFELIAPTTLLLASIIIFFGALTQSLIGFGLAVVASPLLYIVDPDLVPAPVIIMGFTISLLTLFRERGALEFNGLQYALLGRIPGGFLGAALLIFAPQPILGLAIAGIVAAAVILSLMKFNLVVNRKNLFAAGVISGVFGNIAAIGGPPLAILLSGKDANQFRAALSAFFIFSSTIALAILAVTGLLELKQLWLSLLLLPSVILGYLVAGRLVGRVDKNKTRSMTLVLCSISALVLTIKSLIEL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF2</accession>
    <name>ASTD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-succinylglutamate 5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="1">1.2.1.71</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Succinylglutamic semialdehyde dehydrogenase</fullName>
            <shortName evidence="1">SGSD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">astD</name>
        <name type="ordered locus">Swoo_0657</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + N-succinyl-L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:10812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58520"/>
            <dbReference type="ChEBI" id="CHEBI:58763"/>
            <dbReference type="EC" id="1.2.1.71"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family. AstD subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.71" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323300.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDF2"/>
    <dbReference type="SMR" id="B1KDF2"/>
    <dbReference type="STRING" id="392500.Swoo_0657"/>
    <dbReference type="EnsemblBacteria" id="ACA84953">
        <property type="protein sequence ID" value="ACA84953"/>
        <property type="gene ID" value="Swoo_0657"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0657"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_6"/>
    <dbReference type="OMA" id="PFMGPQI"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="UniPathway" id="UPA00185">
        <property type="reaction ID" value="UER00282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043824">
        <property type="term" value="F:succinylglutamate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:arginine catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019545">
        <property type="term" value="P:arginine catabolic process to succinate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07095">
        <property type="entry name" value="ALDH_SGSD_AstD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01174">
        <property type="entry name" value="Aldedh_AstD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017649">
        <property type="entry name" value="SuccinylGlu_semiald_DH_AstD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699:SF197">
        <property type="entry name" value="PTHR11699:SF197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03240">
        <property type="entry name" value="arg_catab_astD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0056">Arginine metabolism</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000138062" description="N-succinylglutamate 5-semialdehyde dehydrogenase">
        <location>
            <begin position="1"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="220"/>
            <end position="225"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01174"/>
        </source>
    </evidence>
    <sequence length="486" mass="51858" checksum="229D08DC55ACACEF" modified="2008-04-29" version="1">MTQFINGQWVAGLGHEVTSKNPANSEVIWSSKTATAEQVNTAVEAAREVQFDWFMLGFEGRLAIVEAYKTQLEEHKAEMAEVIAQETGKPQWETATEAGAMIGKIGLSVAAYNKRTGSSENDTPAGRAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPKVAELMLKLWEKAGLPAGVINLVQGEVETGKALASHEQIDGLFFTGSSRTGHILHQQYAGEPGKILALEMGGNNPLIIKGVKDTKAAVHDIIQSAYISSGQRCTCARRLYVEKGAEGDALLAELADAVKRIQVGAWNSQPQPFMGSMISETAAKGMVESQRNLLNLGGSSLVELTHLKEGTGLVSPGLIDVTQVIELPDEEYFGPLLQVVRYTDFDEAIKLANKTRYGLSAGILADSRDDYEYFLARIRAGIVNWNKQITGASGAAPFGGVGASGNHRASAFYAADYCAYPVASVEADAVSLPASLSPGLSI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU3</accession>
    <name>RF1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptide chain release factor 1</fullName>
            <shortName evidence="1">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prfA</name>
        <name type="ordered locus">Swoo_3685</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326277.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDU3"/>
    <dbReference type="SMR" id="B1KDU3"/>
    <dbReference type="STRING" id="392500.Swoo_3685"/>
    <dbReference type="EnsemblBacteria" id="ACA87945">
        <property type="protein sequence ID" value="ACA87945"/>
        <property type="gene ID" value="Swoo_3685"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3685"/>
    <dbReference type="eggNOG" id="COG0216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036856_0_1_6"/>
    <dbReference type="OMA" id="ISDHRVG"/>
    <dbReference type="OrthoDB" id="928964at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000093504" description="Peptide chain release factor 1">
        <location>
            <begin position="1"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="1">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="361" mass="40500" checksum="539BF50A718CD4A0" modified="2008-04-29" version="1">MKDSVIRKLEGLLERNEEVLALLSDPSVIADQERFRALSKEYSQLEDVVKSFTAFQQATEDLEAAKEMLNEDDPELKEMAQEEMKEAKSVLETLEDELQILLLPKDPNDDNNAFIEIRAGAGGDEAAIFAGDLFRMYSKYSESNRWQIEVMNTNEGEHGGFKEVIAKISGEGVYGKLKFESGGHRVQRVPETESQGRVHTSACTVIVLPEIPEAEAIEINKADLKVDTFRASGAGGQHVNKTDSAIRITHIPTGIVVECQDQRSQHKNRAQAMSVLSARIQAVEDEKRRSEEESTRRNLVSSGDRSERIRTYNFPQGRMSDHRINLTLYRLNEVMEGVLDVIIEPLILENQADLLAALAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDY8</accession>
    <name>B1KDY8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326322.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3730"/>
    <dbReference type="EnsemblBacteria" id="ACA87990">
        <property type="protein sequence ID" value="ACA87990"/>
        <property type="gene ID" value="Swoo_3730"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3730"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_1_2_6"/>
    <dbReference type="OMA" id="HVPKTYE"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="25577" checksum="5F269876329290E6" modified="2008-04-29" version="1">MRLDKYICESTSLTRSLAKKALHRGDVTCDGKVIKDSGFKVTDKQVICLEGEPLSVIGPRFIMLNKPLDTICSTIDEEYPSVLGLLDVVKADELHIAGRLDVDTTGLVLITNDGQWSHKITSPKKECGKRYLLETAEPLKQEWVEEFAAGLQLNNEDGLTKPATLEILGSHQARLTITEGKYHQVKRMLAAVGNCVTQLHRESVGEIELDESLASGEWRYLTEAEIKSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDZ9</accession>
    <name>B1KDZ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sigma54 specific transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3742</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326333.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3742"/>
    <dbReference type="EnsemblBacteria" id="ACA88001">
        <property type="protein sequence ID" value="ACA88001"/>
        <property type="gene ID" value="Swoo_3742"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3742"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_6_6"/>
    <dbReference type="OMA" id="WIVITAQ"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="130"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="430" mass="48099" checksum="8FD9C0E7E5CC9B20" modified="2008-04-29" version="1">MTTPLVNRSVMLWPESLQTDIDKQLIEGLASIGWQFQTSIFKKSSAASVGLAFIDLASLERSRAVLEKEKHCQWIVITAQEELKQIAKRLSLSNVYDYHHRPVDIDILSAMIGHCIGMQQLNTSEPEVHTEGPTKSLNLLYELACKVAKTDVTLLLQGPSGSGKEYLARYIHKNSARHTGPFVSLNCAGIQATLAQDELFGHEKGAFTGADQQHIGAFEQANGGTLLLDEIGDLPMELQGNFLQVLETRHIKRVGSSVLRPIDTRILAASHRNLFELVQEGHFRLDLYYRLNVITLEVPPLAARQDDILPLARRFLLEFESNHHVAKRLSSDAERQLCLHYWPGNVRELHNVITQAAILVDGDIIYAKDIQFSTPSGSGSSLKEHLERAEAEHIRSVLLAHQGNRNKAALQLGISRHTLYRRIKQLDVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE56</accession>
    <name>B1KE56_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0747</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323389.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0747"/>
    <dbReference type="EnsemblBacteria" id="ACA85042">
        <property type="protein sequence ID" value="ACA85042"/>
        <property type="gene ID" value="Swoo_0747"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0747"/>
    <dbReference type="eggNOG" id="COG4965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064305_2_0_6"/>
    <dbReference type="OMA" id="RMQGIVM"/>
    <dbReference type="OrthoDB" id="1002350at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="116"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="283" mass="32362" checksum="ADE0E43C26614AE5" modified="2008-04-29" version="1">MTSAVFSAIFAFFAVAILVWSLKHLSAKFAQKYQETFTSSAKTNLFDMFLFIEPKQLFMLNMITLFSVPFIVRIFLGSWALGIIISIVLAFIPRFAYKFLHKRRRRKFVHQLPDALNMIASSMQSGANVSTAIEFMSEEMQAPIKQEFQLFQREQRLGVEFNTALDNMYKRIPEDEFQLVTAGMQISREVGGNLAEVLFRLSSTLRRKIEMEGKIDALTSQGKMQGIVMTMLPLFIGFVLYHMEPKSMGRILTEPMGWALMALIFIMLTSGYLSIRKIVAIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE58</accession>
    <name>B1KE58_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II and III secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323391.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0749"/>
    <dbReference type="EnsemblBacteria" id="ACA85044">
        <property type="protein sequence ID" value="ACA85044"/>
        <property type="gene ID" value="Swoo_0749"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0749"/>
    <dbReference type="eggNOG" id="COG4964">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017952_4_0_6"/>
    <dbReference type="OMA" id="DWSTIGN"/>
    <dbReference type="OrthoDB" id="870677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032789">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13629">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SS-T3SS_pil_N" evidence="2">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="436" mass="47572" checksum="B9F390969A9AA64A" modified="2008-04-29" version="1" precursor="true">MNSRKLIAIIWACIFIPLVSYAHNNTPLKLYMGAVELYNAKNVERIVVGNGKVLSAKVIDDKGVLLIAESPGNTDVQLWQKDGKLIKLSISVTPDNSLKTTDTIKKMLAAFPSIKVTENDGLIIVQGEADLSQKEQLETIIEADPNVVSLIKYLKFAKTMAPMIKMQVKIVEFNKSTLNNIGIKWESSMAGPAYGAAKAFSANPIFSVSSPGQYSETITSAITDSIGVLDTRGWNYFGIVTGIGSQIQLLSEKGDARMLAEPNLTTRSGESANFLAGGEFPIRSVSGLGAVDVEYKEYGIKLDIEPVVDDDLNIVSRVMAEVSSIDPSVAVDGIPGMLTRRTESVINVKNNETIVISGLVNSEMSKIVNKFPLLGDIPILGELFKSRDFKDNKSELVIFVTPTVVYPGEESHDKQLERGLEMAEETNKLEAFYILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE85</accession>
    <name>B1KE85_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfite reductase [NADPH] flavoprotein alpha-component</fullName>
            <shortName evidence="10">SiR-FP</shortName>
            <ecNumber evidence="10">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_0776</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -&gt; FAD -&gt; FMN to the hemoprotein component.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>3 H2O + hydrogen sulfide + 3 NADP(+) = 4 H(+) + 3 NADPH + sulfite</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10 11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="10 11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323418.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0776"/>
    <dbReference type="EnsemblBacteria" id="ACA85071">
        <property type="protein sequence ID" value="ACA85071"/>
        <property type="gene ID" value="Swoo_0776"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0776"/>
    <dbReference type="eggNOG" id="COG0369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_17_7_6"/>
    <dbReference type="OMA" id="QKRYQRD"/>
    <dbReference type="OrthoDB" id="707164at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010199">
        <property type="entry name" value="CysJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000207">
        <property type="entry name" value="SiR-FP_CysJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01931">
        <property type="entry name" value="cysJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 10 11" id="KW-0288">FMN</keyword>
    <keyword evidence="6 10 11" id="KW-0521">NADP</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="12">
        <location>
            <begin position="61"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="230"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="67"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="114"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="382"/>
            <end position="385"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="400"/>
            <end position="402"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="415"/>
            <end position="418"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="514"/>
            <end position="515"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="520"/>
            <end position="524"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="556"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="594"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000207-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="594" mass="65581" checksum="B155F45E241E1686" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KED2</accession>
    <name>B1KED2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324854.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2229"/>
    <dbReference type="EnsemblBacteria" id="ACA86510">
        <property type="protein sequence ID" value="ACA86510"/>
        <property type="gene ID" value="Swoo_2229"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2229"/>
    <dbReference type="eggNOG" id="COG4872">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055073_1_0_6"/>
    <dbReference type="OMA" id="CRSRWIF"/>
    <dbReference type="OrthoDB" id="552712at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018677">
        <property type="entry name" value="DUF2157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09925">
        <property type="entry name" value="DUF2157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2157" evidence="2">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="445" mass="50074" checksum="9CCBDB08CAA7F30D" modified="2008-04-29" version="1">MRLINLFKKELAHEARDWVRDELVSDAQASAILARYGESLDEDPNKNSFGYYLLMSLGALFLGLALILIVSHNWEEIPRVIRTTGLLLLTFSCGVIGSKLFLSGREQAGKIWLFFGGISYGTSIMLVAQIYHLGEHFPDGIFWWAAGILPLVIFTQSRLLALLSFTLATIWAMVETGEDFFPALYPIFAVVTLWLTLFKKTSRLLFVGSIAALVTWFNLALAWAMGGAGYFELFEEQLPLSIAIGILLNGLAWWLMRSKDHDWQEYGLVTHIWLLRGSIITLLVLSFEGVWQDYPMGFDWLSLLGITTLLLFGCLSWGLSRKSGLYASTPAILMTFYFVLCFALVGAFDNMELITAIATNLMLVVMGILLIRRGIDQTQTHYFYTGVVTLLLTAFFRYFDLIGDYIGGAILFMVAAAILMAAAKYWKYHLKLVTKVDDTQVREGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE6</accession>
    <name>B1KEE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2243"/>
    <dbReference type="EnsemblBacteria" id="ACA86524">
        <property type="protein sequence ID" value="ACA86524"/>
        <property type="gene ID" value="Swoo_2243"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2243"/>
    <dbReference type="eggNOG" id="COG4949">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035873_0_0_6"/>
    <dbReference type="OMA" id="HSEFTTY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021830">
        <property type="entry name" value="DUF3422"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11902">
        <property type="entry name" value="DUF3422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="458" mass="52603" checksum="095E7DFC203694C0" modified="2008-04-29" version="1">MNQAIKESVIAPESLVSECLNNEEACEARFEQRSIPVSPLRQQISLELHNRPSPKVGIPTCVSHLAIRVNLEQRQREYQHLSAFCHRYSVNPPCIDAGCFFQDFGGFELRWERHLEFSTYSFIRKGQGMQLFDGYSTERVPQDWFDELVGELICAINLTFSKDELSEREIYQAFEGQQVIGSLVADGRARVYSSFRLHSDGFSRTIIQSEQLNSYQAGRLIQRTLEIETYQMLALLSLPIARELSPKVSQMESELVALNQQMANLSQHDDSEMLDKLSNLAGQTEQLIADISYRFSATNAYYALVCARLEQLKEQDITGVERINEFVTRRLNPGIRTCQALTQRLEDLTRRIARASSLLRTRVDLSIEQQNQQLLHAINQRGKIQLRLQQMVEGVSVAAMAYYLMGLLEYILSALNANGYQFNKLMFKGVAVPVFLFFAWWLLRFAMGYIRKEPERPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE7</accession>
    <name>B1KEE7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Porin_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2244"/>
    <dbReference type="EnsemblBacteria" id="ACA86525">
        <property type="protein sequence ID" value="ACA86525"/>
        <property type="gene ID" value="Swoo_2244"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2244"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032382_1_0_6"/>
    <dbReference type="OMA" id="GANGWKF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766989" description="Porin_4 domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="4">
        <location>
            <begin position="13"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="387" mass="41654" checksum="69391BCEDBF33789" modified="2008-04-29" version="1" precursor="true">MMNTQAKLSLLSVAICMTTFNASAALEIYENDGMSFSADGLVNAFYANSSIEKTDAEGATSERDQSRVRTGFLPNNIGFNFSNQLSDMKIGMRSSFWVSISDADNHRDASPADLGTGSLIDIRQFYGTVSGDWGELLVGKDFGLLNRANILGDELLLGFGQTSDFFGLVDGGNVSFGNISTGYTYPFPKSQITYRSPDLNGFKIAVGLMDPNKVAADSSEELPRAEAELIYSTEMDKVNLKAWVSGATQSSEVDDVKQNQSGVGYGANVKFSGFSFTASGFQTKGLGHIAGLDHLVGDESIKSDGYLLQAAYTLDSNRFVLTYGESEVENTDSILDAKHSNIGIAYFRTIRPGLTAVVEYNQTEADVANSLVGEENNTLSIGAVFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF8</accession>
    <name>B1KEF8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">PQQ-dependent dehydrogenase, methanol/ethanol family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_2255</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyrroloquinoline quinone</name>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial PQQ dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324879.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2255"/>
    <dbReference type="EnsemblBacteria" id="ACA86536">
        <property type="protein sequence ID" value="ACA86536"/>
        <property type="gene ID" value="Swoo_2255"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2255"/>
    <dbReference type="eggNOG" id="COG4993">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018478_0_0_6"/>
    <dbReference type="OMA" id="YVPANEW"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10277">
        <property type="entry name" value="PQQ_ADH_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034119">
        <property type="entry name" value="ADHI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017512">
        <property type="entry name" value="PQQ_MeOH/EtOH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001479">
        <property type="entry name" value="Quinoprotein_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01011">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03075">
        <property type="entry name" value="PQQ_enz_alc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00364">
        <property type="entry name" value="BACTERIAL_PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 9" id="KW-0634">PQQ</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766498" evidence="12">
        <location>
            <begin position="27"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrroloquinoline quinone binding" evidence="9">
        <location>
            <begin position="419"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>pyrroloquinoline quinone</name>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>pyrroloquinoline quinone</name>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>pyrroloquinoline quinone</name>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="130"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR617512-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR617512-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR617512-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR617512-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="588" mass="64395" checksum="22D0B4DD91E6C736" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEG8</accession>
    <name>B1KEG8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5'-deoxynucleotidase Swoo_2265</fullName>
            <ecNumber evidence="1">3.1.3.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5'-deoxyribonucleotidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5DNU family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324889.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2265"/>
    <dbReference type="EnsemblBacteria" id="ACA86546">
        <property type="protein sequence ID" value="ACA86546"/>
        <property type="gene ID" value="Swoo_2265"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2265"/>
    <dbReference type="eggNOG" id="COG1896">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084784_0_0_6"/>
    <dbReference type="OMA" id="NQSHFFA"/>
    <dbReference type="OrthoDB" id="1508841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01100">
        <property type="entry name" value="5DNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022971">
        <property type="entry name" value="YfbR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="28"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="75"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="site" description="Appears to be important in orienting the phosphate for catalysis" evidence="1">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="195" mass="22353" checksum="3F673BDCFC8FDFF2" modified="2008-04-29" version="1">MSHLFAHLARMKLIQRWPLMYNVRSENVQEHSLQVAMVAHALAIISNQKFGTKLSPDRAATVAIFHDASEILTGDLPTPVKYFNKEIEAEYKKIEAIAEHRLLEMVPEEFQQEYQPLLSSEHADSEYKLLVKSADTICAFLKCLEELRAGNNEFNTARKRLIESLDKNPDPAVKYFVDCYVPSFKLSLDDINKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ9</accession>
    <name>B1KEQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326405.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88074">
        <property type="protein sequence ID" value="ACA88074"/>
        <property type="gene ID" value="Swoo_3815"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3815"/>
    <dbReference type="eggNOG" id="ENOG5032HXA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158707_1_0_6"/>
    <dbReference type="OMA" id="WVQKHAN"/>
    <dbReference type="OrthoDB" id="2037676at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025284">
        <property type="entry name" value="DUF4144"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13642">
        <property type="entry name" value="DUF4144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="117" mass="13383" checksum="B28B3F1BF04A37ED" modified="2008-04-29" version="1">MKKRKNSAEINWPAILIQPQQKELIYLESKSAWLIESQHTIDIEAQLIDSLGKSYQLREDAGRGPVWSEGSQNIRLEKLIEMIKVHASLTGHCCSAKLGAKDFPQAFEIIHYLENEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU7</accession>
    <name>B1KEU7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0803</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323445.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85098">
        <property type="protein sequence ID" value="ACA85098"/>
        <property type="gene ID" value="Swoo_0803"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0803"/>
    <dbReference type="eggNOG" id="ENOG5031T1X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2773606_0_0_6"/>
    <dbReference type="OMA" id="AHCAKED"/>
    <dbReference type="OrthoDB" id="2087560at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="69" mass="7896" checksum="9B2A87D0B92824AE" modified="2008-04-29" version="1">MPYRTRDITPKYVNFTVNQGLYQSSSSYRCRVDFVVKLLGSETMASNGLETDGFTDVINEEKDFILGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU8</accession>
    <name>B1KEU8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323446.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0804"/>
    <dbReference type="EnsemblBacteria" id="ACA85099">
        <property type="protein sequence ID" value="ACA85099"/>
        <property type="gene ID" value="Swoo_0804"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0804"/>
    <dbReference type="eggNOG" id="ENOG50315U8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1634254_0_0_6"/>
    <dbReference type="OMA" id="IGSWVKI"/>
    <dbReference type="OrthoDB" id="1967251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="17851" checksum="3ED8C328B166BB09" modified="2008-04-29" version="1">MVSNKVNYIFLSVGLVAFLGVLGSVLYLSLNSRDDSADLQPVVMGLWVKMPGFCEGKVTEVEKMELLTASSLRIDGQLITISGFNLSQTSPLKVQCETLGEGSMYAQTSFLGNRFSRFYIGNIGEYTVLKEVTPGGAFWFKHDQVLAQKLQTMKGVPNINRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEY5</accession>
    <name>B1KEY5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type sugar transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323483.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85136">
        <property type="protein sequence ID" value="ACA85136"/>
        <property type="gene ID" value="Swoo_0841"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0841"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048104_0_0_6"/>
    <dbReference type="OMA" id="NEQYVAP"/>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764774" evidence="1">
        <location>
            <begin position="23"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="64"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="399" mass="44948" checksum="4CB2A569601CFAD3" modified="2008-04-29" version="1">MLLGLRVIAFSLFCLLAFDLPAKEPALHSVEYAHSDVLQSQVPILKSSADACSNKHAAPRVMVIMPLDRTSTFWENIVKHMKLAAEQLTINLDVHYLKQSDSRRFNYSEYLNRVLASSERPDYLVTPFFKGLEKTLLELTSQEKISLFTFNVPLSDEMTATLGFPRERYPYWIGHISPDEVDAGYQLADRLIQLAAKNSTDAVKLIAVNGDRTGVVGQLREKGLMQRLALSPDVELLQLVDAKWMPGKAQYMASRLVRRHQDIDLFWAASDHIAMAVVNALADYEATMDKAIVGSIDWTKEIGSYIENRSVGVSFGGHIFEGAWILPLLYDHYNHQDFAKELTSVISYKMQGITAKNSVLLKANNINKIDFSYLSQCFTGNGGVYHFSPLKQLTQYDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEZ2</accession>
    <name>B1KEZ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323490.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0848"/>
    <dbReference type="EnsemblBacteria" id="ACA85143">
        <property type="protein sequence ID" value="ACA85143"/>
        <property type="gene ID" value="Swoo_0848"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0848"/>
    <dbReference type="HOGENOM" id="CLU_2318547_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="11239" checksum="E8BFD85C84CE4ECB" modified="2008-04-29" version="1">MFSPRSAALHGGKDGGRDYGFWFSPWPSVFSVVNGFYLGKCKRTGFALLGSRALRFELRKEQRKEQRQEQRQEHLLPLSAALHGGKDGGRDYGFQIYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFA0</accession>
    <name>B1KFA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2362</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324983.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2362"/>
    <dbReference type="EnsemblBacteria" id="ACA86641">
        <property type="protein sequence ID" value="ACA86641"/>
        <property type="gene ID" value="Swoo_2362"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2362"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_2_6"/>
    <dbReference type="OMA" id="HKHDFFI"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="190"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="33625" checksum="DE8F4F0E97F39D69" modified="2008-04-29" version="1">MNKKTPKLSFKKELNLIGFEILSLEELYSRKAPSFLTRSKILQFYIVIFIVEGQGEHFIDFNAHDISKGSIIFIGKNQAHAWQKYRSCEGFAILFTDNFLYKNQVEFNTLSYDYPFNPILYNQVISVSEQAQFESFKSLIRFISEEYALSSYATQQKVLQTLLRTLLLKVHCLLVKSDSTTKKQSKELFVRLQKILDQNIMHTKTANDYIALLGVSYHQVNSVVKQYTNKSLKLFIDDTLILHAKRLLSNDNNISQSAIALGFDEATNFTKFFKKRTGQTPKEFKEFISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC5</accession>
    <name>B1KFC5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325008.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2387"/>
    <dbReference type="EnsemblBacteria" id="ACA86666">
        <property type="protein sequence ID" value="ACA86666"/>
        <property type="gene ID" value="Swoo_2387"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2387"/>
    <dbReference type="eggNOG" id="ENOG502ZCJR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_769239_0_0_6"/>
    <dbReference type="OMA" id="KCISPAF"/>
    <dbReference type="OrthoDB" id="900050at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="353" mass="39736" checksum="E938600D3F397EEF" modified="2008-04-29" version="1">MEQLPKEETGVRFQKIINSPINLLLGSFLSLRSYYQKMVSLLKRLTLAQKLYLFALLLLMSPDYLGLVVIITVVALTLEFWPLFERVWHSLSGKAVLLLFYAVIANFAIAGAASVVNEVVGVSTTHFSYTHNFAILLYLPAWVIAMTALAILLLQIAVPIYLVFLLMLKPFGVKGLRLTNHNHFRFSTMLVRVILASIVLYHLVLLVNLDNELSDEVAFTEESDAVAVAVAENVHNQLIESFNQTEGLPVELSSMSDNLSIGLSLSSEETKKSNEELYENVRSDYEKVVRNLIAIFAFHLESDTKSRCEMEQDTNVVELNDYEILEIKEDLEADYGYSFVVKKCISPAFPAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFD7</accession>
    <name>B1KFD7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326442.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3854"/>
    <dbReference type="EnsemblBacteria" id="ACA88112">
        <property type="protein sequence ID" value="ACA88112"/>
        <property type="gene ID" value="Swoo_3854"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3854"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015312_0_0_6"/>
    <dbReference type="OMA" id="WGPWTRK"/>
    <dbReference type="OrthoDB" id="330793at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="49"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="574" mass="64321" checksum="C73A1B86F9FCE4D5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFH1</accession>
    <name>B1KFH1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326476.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3888"/>
    <dbReference type="EnsemblBacteria" id="ACA88146">
        <property type="protein sequence ID" value="ACA88146"/>
        <property type="gene ID" value="Swoo_3888"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3888"/>
    <dbReference type="eggNOG" id="COG3647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087528_0_0_6"/>
    <dbReference type="OMA" id="WDTQWDM"/>
    <dbReference type="OrthoDB" id="1341485at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014509">
        <property type="entry name" value="UCP020606"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09997">
        <property type="entry name" value="DUF2238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020606">
        <property type="entry name" value="UCP020606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="200" mass="22639" checksum="AC4CCEAF90EC0BFC" modified="2008-04-29" version="1">MNKQHIWLTIFLLVLIWSGINPKDQFTWFLEVAPALIALPVMFFTRKRFPLTPMLYVLILIHCVILMVGGHYTYAEVPLFDWIADALGSDRNNYDKVGHFAQGFIPALIAREVFIRNQVVKPGVWCSFICVCFALALSAFYELIEWWVALLTGEDAEAFLGTQGYIWDTQSDMGMALLGAIVALLVLVKTHNKQLAALND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL7</accession>
    <name>B1KFL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326522.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3935"/>
    <dbReference type="EnsemblBacteria" id="ACA88192">
        <property type="protein sequence ID" value="ACA88192"/>
        <property type="gene ID" value="Swoo_3935"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3935"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_0_1_6"/>
    <dbReference type="OMA" id="FARMGHW"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="21838" checksum="2901416F674379DD" modified="2008-04-29" version="1" precursor="true">MSISIFMTLFMVSLLGAMSPGQSVIMVARNTLAGGRAQGIITACAHSIGVGLYAGLSLAGLALVLKNSPLFYNTITYLGAAYLAWLGICSLRSKGGITDKLNSGKQMSLYQAARSGFVISILNPKIIIFYLALFSQFVENADSMVNRIIIVTTPTVLDAVWYIFIACMLSKPTTLIRLRQHAQTIDKVSGMLLLLLAGRILIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ8</accession>
    <name>B1KFQ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323571.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85224">
        <property type="protein sequence ID" value="ACA85224"/>
        <property type="gene ID" value="Swoo_0931"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0931"/>
    <dbReference type="eggNOG" id="ENOG5032B62">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_206422_0_0_6"/>
    <dbReference type="OMA" id="NLEPNMS"/>
    <dbReference type="OrthoDB" id="1998946at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="62" mass="6361" checksum="2865C04C64CE8FB3" modified="2008-04-29" version="1">MAITIGTANLEPNLSNGNIGVKVAQLAKEQQQAEGEIALQLIQATEPAAPSGNAGHNINIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFX2</accession>
    <name>B1KFX2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein involved in aromatic hydrocarbon degradation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2401</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2401"/>
    <dbReference type="EnsemblBacteria" id="ACA86679">
        <property type="protein sequence ID" value="ACA86679"/>
        <property type="gene ID" value="Swoo_2401"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2401"/>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039022_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="428" mass="45965" checksum="512DDCF91604ACD2" modified="2008-04-29" version="1">MSLHNVCYTTLKQQESDVSLVQSKKLILGALGALVAAVPSVGLASGFDRGVVPPDFLYEKDDIVQVSLAVVKPDVRGKIVASPKATLEAQASFLQGQAAANPGNLALQQQAAQVTYLASKAPAVGQETGNLPGDYERKGISLKKTINDDFTIGLQVTQPAGLDIAYPDEIFGVYVETEITSLDLLLKYQVNDVFSVFGGPRIQQNSSGGFANDLNGEFHYQGTTEVGYMVGAGYKNPDLHTQVLVSYTSDIKHTMDATPISGSGPVADGVIATDYEGEVYINTPDHFQVAIKQPLSDKSALIASYRKSGWSQANIETNLAGFESLTDFKDVEAYTLGYGRKLTEEVALFATLLHQTGEANVFGPVNNRTGAALIAQFKVDRFKVETGVTYFDLEDAETTIPMGAAGDVVTKFEGNSALAYTFRLGYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG19</accession>
    <name>B1KG19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2449</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325068.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2449"/>
    <dbReference type="EnsemblBacteria" id="ACA86726">
        <property type="protein sequence ID" value="ACA86726"/>
        <property type="gene ID" value="Swoo_2449"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2449"/>
    <dbReference type="HOGENOM" id="CLU_713507_0_0_6"/>
    <dbReference type="OrthoDB" id="587302at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PTHR35870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="387" mass="42839" checksum="B0240A051D44495A" modified="2008-04-29" version="1">MRNINNSIQSSAELTAFVNHEMRQDGRYHPNLGGVTRSGMANHFPMTIMSLAALGGSDTDIKRFKSHWPASRYRSLIEDLGLRDTDSVTLNNWPDYLGKAEFLIEFKRVFLEGLTNLGAERFIHHALNIMADSLPMGLFHPLIKLSFARMQGDDALIADALAYFAIRYQDLYGELGSMKTDEASSIDVSDVSDVSDGQDALLTSWGRAALKVESGEVKLSTSGASLPVSETLCGSSTVHQLALNQGFSITEANFSCQIAEICKAAAALYLYEPALTTLHAVTSAQALVDLTLSLQNSDRKLAVKLWQRYWIWLTGLYLEKGAPKLTFSGVYSAADLLPDWNSLAKTAVKIDEVHEIKMVFSCKWLAQNLEDHEIYRIVASQVLAEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG86</accession>
    <name>B1KG86_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase/Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326553.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3966"/>
    <dbReference type="EnsemblBacteria" id="ACA88223">
        <property type="protein sequence ID" value="ACA88223"/>
        <property type="gene ID" value="Swoo_3966"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3966"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_353327_0_0_6"/>
    <dbReference type="OrthoDB" id="1300173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032179">
        <property type="entry name" value="Cry22Aa_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16403">
        <property type="entry name" value="DUF5011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5011" evidence="2">
        <location>
            <begin position="42"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="623"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="795" mass="85395" checksum="EA08064D2F61FB2E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE4</accession>
    <name>B1KGE4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326610.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4025"/>
    <dbReference type="EnsemblBacteria" id="ACA88281">
        <property type="protein sequence ID" value="ACA88281"/>
        <property type="gene ID" value="Swoo_4025"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4025"/>
    <dbReference type="eggNOG" id="COG4519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168306_0_0_6"/>
    <dbReference type="OMA" id="IELMFVQ"/>
    <dbReference type="OrthoDB" id="1837288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017162">
        <property type="entry name" value="UCP037266"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09904">
        <property type="entry name" value="HTH_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037266">
        <property type="entry name" value="UCP037266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="10980" checksum="45EEE76916A84911" modified="2008-04-29" version="1">MDIEISKQKKAFLRKLYLAHHIDSEQHNLLSLNKLTGMPRRTLQDAIAVLGDIGIECRFIQDGERNNSGYYRIITWGPISSAWVDTHLSEITEILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGF9</accession>
    <name>B1KGF9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323634.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0994"/>
    <dbReference type="EnsemblBacteria" id="ACA85287">
        <property type="protein sequence ID" value="ACA85287"/>
        <property type="gene ID" value="Swoo_0994"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0994"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_12_2_6"/>
    <dbReference type="OMA" id="VDIGTIA"/>
    <dbReference type="OrthoDB" id="1819702at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034343">
        <property type="entry name" value="YibF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF12">
        <property type="entry name" value="PTHR42673:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="198" mass="22784" checksum="B7A392DA70AB18BE" modified="2008-04-29" version="1">MRLLYSDASPYSRCVRVLIRHLEITGVEECIVDPMENSELLLELNPLGKIPCLQLNDGSSLYDSEVILRYLDHEFGANRLFGEYGYNWKNECQLSLINGLLDSAVALRQEQMRELEGKRSLFWTSRFEMALLRGLKEIEQSGVMVSPQLTIQQIGLACLLEYLDFRHADLQWRKVVPATATWLSGFEHLSMMKSTRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS0</accession>
    <name>B1KGS0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PAAR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2512</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325130.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2512"/>
    <dbReference type="ESTHER" id="shewm-b1kgs0">
        <property type="family name" value="Duf_2974"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86789">
        <property type="protein sequence ID" value="ACA86789"/>
        <property type="gene ID" value="Swoo_2512"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2512"/>
    <dbReference type="eggNOG" id="COG4104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_592988_0_0_6"/>
    <dbReference type="OMA" id="LLHACPC"/>
    <dbReference type="OrthoDB" id="1960797at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024499">
        <property type="entry name" value="Mbeg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11187">
        <property type="entry name" value="DUF2974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="461" mass="47782" checksum="A159B8E70FE0372B" modified="2008-04-29" version="1">MPKAARLGDSCAGHGCMPATPIIAGSGDVSINGKPAARKGDTVLLHACPCPNMPHGIHGRSISAGSSNVSINGKPAARVGDAVGCGGSVAAGSGDVLIGDTPYKSPTHKCGENAVKDNTPLLAMAPMPILAAIKWGEPANQFITADSVVTTVKQRKARYQARKKLASSTANESDPKIKAASERLDFNNDSILRAEAAQYVYRVDENRRDPAKYPLPEAPVGLEVLDTKTIPGLENAVVMSKKSGFGAAIFKSEINDATMLTYRGTNNGVTGKKDWKTNGAQGIGKQTKQYDQAMHLARQVKRSLGKEVEIVGHSLGGGLAASAVGVTGIKGYSFNSAGLHENTVSRQGGLKMEKIKGLIQSQSVDGEVLTLLQSNRGVVAPLLAGVGSALGGTVGTAIGGILGAAILNSGAAPEAPGNMRELKSIEGGNPVTRHGMDQVIAGIEAQKKQDITTLTQYHWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT0</accession>
    <name>B1KGT0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein, VC_A0114 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325140.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2522"/>
    <dbReference type="EnsemblBacteria" id="ACA86799">
        <property type="protein sequence ID" value="ACA86799"/>
        <property type="gene ID" value="Swoo_2522"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2522"/>
    <dbReference type="eggNOG" id="COG3522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031690_3_0_6"/>
    <dbReference type="OMA" id="YTYFELD"/>
    <dbReference type="OrthoDB" id="496911at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010263">
        <property type="entry name" value="T6SS_TssK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35566">
        <property type="entry name" value="PTHR35566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05936">
        <property type="entry name" value="T6SS_VasE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03353">
        <property type="entry name" value="VI_chp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="444" mass="50261" checksum="26E72BF63D130241" modified="2008-04-29" version="1">MSSRNRVIWAEGLFIKPQHFQQQQRYFEYVTDERMTSVNSYLYGISQLELNPEYLGFGRIAIQRAKGVMPDGTVFNIPQEDVLPSALEVVDGSLANQIVYLALSLRSDSITEVTESTSSGNTRFVTHRHEVRDIHSEQGDFSTIDVSPVQMKLMFEKEDRSAYSSVAIAKILEKRPDGSVVLDPNFIPCHYNVLGVPFLHRFIGEMAGMMRERAKNIAVRIGSPSQGGVADVSDFMLLQALNRMQPVLQHLSQLKSLHPEQLYQTLVSICGELFSFTDDSRIAPIFKPYDHDMPITSFGQLMNMLRQSLSIVLEPKAVSLQLQKRKYGLMVAPVQDPDLIKEADFILAVRAKLPLEELKKLFIQQTKIASVEKIRELISLQLPGVGLTPLPVAPRQLPYHAGYTYFQLDRTSPSWEMLQHSTGFAFHVAGEFPELELQFWAIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV0</accession>
    <name>B1KGV0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A dehydrogenase</fullName>
            <ecNumber evidence="6">1.3.8.7</ecNumber>
            <ecNumber evidence="7">1.3.8.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_2542</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:17721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83721"/>
            <dbReference type="ChEBI" id="CHEBI:83727"/>
            <dbReference type="EC" id="1.3.8.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:14477"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83723"/>
            <dbReference type="ChEBI" id="CHEBI:83726"/>
            <dbReference type="EC" id="1.3.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="6"/>
    <dbReference type="EC" id="1.3.8.8" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325160.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2542"/>
    <dbReference type="EnsemblBacteria" id="ACA86819">
        <property type="protein sequence ID" value="ACA86819"/>
        <property type="gene ID" value="Swoo_2542"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2542"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012192_0_0_6"/>
    <dbReference type="OMA" id="KYHMTEM"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004466">
        <property type="term" value="F:long-chain-acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015396">
        <property type="entry name" value="DUF1974"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09317">
        <property type="entry name" value="DUF1974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="13">
        <location>
            <begin position="83"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="12">
        <location>
            <begin position="194"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="11">
        <location>
            <begin position="317"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1974" evidence="14">
        <location>
            <begin position="471"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA86819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="758" mass="83552" checksum="0DBD90C1D40A155D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX8</accession>
    <name>B1KGX8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325187.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86847">
        <property type="protein sequence ID" value="ACA86847"/>
        <property type="gene ID" value="Swoo_2570"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2570"/>
    <dbReference type="eggNOG" id="ENOG50342ZN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108500_0_0_6"/>
    <dbReference type="OMA" id="NDYHQGR"/>
    <dbReference type="OrthoDB" id="1801861at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="199" mass="22349" checksum="4CECA4AF1CF0FEFC" modified="2008-04-29" version="1">MYKSLFTYRDKNTPKKEVQRFVVVYFSPKLNLTKIAHRAVKAVYKTRVSKLITLLIISFPFHATAAITITEIQPLKYPSAIKNSSKSSIVVVNWKGKLGKATNTTLLDNDYHQGRYLITSDSTAPISIDFFQLANEYKINLKSLRVRYKNQTLKSFPASGLASPGLEGEYIDIGAKVVAGKNATPGMKSPQYILRIEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH30</accession>
    <name>B1KH30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4086</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326671.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4086"/>
    <dbReference type="EnsemblBacteria" id="ACA88342">
        <property type="protein sequence ID" value="ACA88342"/>
        <property type="gene ID" value="Swoo_4086"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4086"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_6"/>
    <dbReference type="OMA" id="YPRITWI"/>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="30703" checksum="5B4C752A93D8EACC" modified="2008-04-29" version="1" precursor="true">MIERIVQETEILKVDNLSWHADEREILSGIHFCLTKGEMLGIIGPNGAGKSSLLRCLYRYIKPSSGAITLFGDEIATLSAKEFAKRVAVVLQDTPHHFDLTTAQLVAIGLTPHKGPFEITTAKDREVINDALAKVGLTHKAGQAYEHLSGGEKQRALIARAIVQRPKLLILDEPTNHLDIRYQIQILELLRSLNISVITSIHDLNLASALCDQLLLLDGGKCISHGAPVEVLTEQRIGDVFGVCCKVEPHPQHANPQISYFYGYSSIKEKQGRQDDSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH59</accession>
    <name>B1KH59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent transcriptional regulator, MalT-like, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88371">
        <property type="protein sequence ID" value="ACA88371"/>
        <property type="gene ID" value="Swoo_4115"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4115"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_347452_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="729"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="797" mass="90221" checksum="852C7F0E3E1B92BC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH88</accession>
    <name>B1KH88_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323742.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1103"/>
    <dbReference type="EnsemblBacteria" id="ACA85396">
        <property type="protein sequence ID" value="ACA85396"/>
        <property type="gene ID" value="Swoo_1103"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1103"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091970_0_0_6"/>
    <dbReference type="OMA" id="HISAFRG"/>
    <dbReference type="OrthoDB" id="1940131at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010718">
        <property type="entry name" value="DUF1294"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06961">
        <property type="entry name" value="DUF1294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="23075" checksum="2E9A8B75678DEFDD" modified="2008-04-29" version="1">MKFKGKLVQWDDVKGFGFIQPLGQQTQVFVHIKSFKYQPRRPQLQDTVTFTLTKDKQGRETAHQAKIIDAKAKAHLLRKTPSQGKFSLLLILSLAASLAMALYHDLLPSFSPLIYLLMSTITFIAYALDKSAARKGRWRTKESTLQLMALLGGWPGALLAQSWLRHKSQKVSFRVTLWCMIVLNSASLYWFTSSMGQTWLQAL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-06-16" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHU9</accession>
    <name>MIAA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="1">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="1">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="1">IPP transferase</shortName>
            <shortName evidence="1">IPPT</shortName>
            <shortName evidence="1">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">miaA</name>
        <name type="ordered locus">Swoo_4171</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IPP transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326756.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHU9"/>
    <dbReference type="SMR" id="B1KHU9"/>
    <dbReference type="STRING" id="392500.Swoo_4171"/>
    <dbReference type="EnsemblBacteria" id="ACA88427">
        <property type="protein sequence ID" value="ACA88427"/>
        <property type="gene ID" value="Swoo_4171"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4171"/>
    <dbReference type="eggNOG" id="COG0324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032616_0_0_6"/>
    <dbReference type="OMA" id="YAKRQYT"/>
    <dbReference type="OrthoDB" id="1069591at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000377322" description="tRNA dimethylallyltransferase">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <begin position="27"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <begin position="151"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <begin position="232"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="2"/>
            <end position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="4"/>
            <end position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <sequence length="296" mass="33555" checksum="FB4F42EB7CCE18B1" modified="2008-04-29" version="1">MGPTASGKTALAIALVEQHNCEIISVDSALIYRGMDVGSAKPNAEELGKAPHRLIDIRDPAESYSAADFRTDALQAIEEILAKGKTPLLVGGTMMYFKALLEGLSPLPAADDEIRKQIQIEADTYGWNHLHDELKQIDPVSAERIHPNDPQRLSRAIEVYRISGKSLTELTKIKSEPLPYDVVQFAISPKDRKQLHLSIEERFKLMLNQGFVEEVRSLRERSELHIDLPSMRCVGYRQCWQYLNGDYDYDTMVEKAVVATRQLAKRQLTWLRGWPELNWLESGSDSNLTTVLRHCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHW0</accession>
    <name>B1KHW0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4182</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326767.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4182"/>
    <dbReference type="EnsemblBacteria" id="ACA88438">
        <property type="protein sequence ID" value="ACA88438"/>
        <property type="gene ID" value="Swoo_4182"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4182"/>
    <dbReference type="eggNOG" id="COG3264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007829_2_0_6"/>
    <dbReference type="OMA" id="MALITFD"/>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006686">
        <property type="entry name" value="MscS_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025692">
        <property type="entry name" value="MscS_IM_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12794">
        <property type="entry name" value="MscS_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01246">
        <property type="entry name" value="UPF0003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767073" evidence="9">
        <location>
            <begin position="23"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="576"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="645"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="672"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="753"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="807"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="844"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="875"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="MscS_TM" evidence="10">
        <location>
            <begin position="449"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="34"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="174"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="243"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1070" mass="121834" checksum="A5D7300C4E8BEF40" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI55</accession>
    <name>LEPA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor 4</fullName>
            <shortName evidence="1">EF-4</shortName>
            <ecNumber evidence="1">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lepA</name>
        <name type="ordered locus">Swoo_1241</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323879.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI55"/>
    <dbReference type="SMR" id="B1KI55"/>
    <dbReference type="STRING" id="392500.Swoo_1241"/>
    <dbReference type="EnsemblBacteria" id="ACA85533">
        <property type="protein sequence ID" value="ACA85533"/>
        <property type="gene ID" value="Swoo_1241"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1241"/>
    <dbReference type="eggNOG" id="COG0481">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009995_3_3_6"/>
    <dbReference type="OMA" id="MVQIAIQ"/>
    <dbReference type="OrthoDB" id="182107at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000092446" description="Elongation factor 4">
        <location>
            <begin position="1"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="2"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <sequence length="596" mass="65634" checksum="AE31CEEC206E911E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI60</accession>
    <name>B1KI60_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxine 5'-phosphate synthase</fullName>
            <shortName evidence="2">PNP synthase</shortName>
            <ecNumber evidence="2">2.6.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pdxJ</name>
        <name evidence="3" type="ordered locus">Swoo_1246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="EC" id="2.6.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.99.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323884.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1246"/>
    <dbReference type="EnsemblBacteria" id="ACA85538">
        <property type="protein sequence ID" value="ACA85538"/>
        <property type="gene ID" value="Swoo_1246"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1246"/>
    <dbReference type="eggNOG" id="COG0854">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074563_0_0_6"/>
    <dbReference type="OMA" id="SNAGWDT"/>
    <dbReference type="OrthoDB" id="1159993at2"/>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033856">
        <property type="term" value="F:pyridoxine 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00003">
        <property type="entry name" value="PNPsynthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00279">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004569">
        <property type="entry name" value="PyrdxlP_synth_PdxJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036130">
        <property type="entry name" value="Pyridoxine-5'_phos_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30456">
        <property type="entry name" value="PTHR30456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03740">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63892">
        <property type="entry name" value="SSF63892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00559">
        <property type="entry name" value="pdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="1-deoxy-D-xylulose 5-phosphate binding" evidence="2">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-amino-2-oxopropyl phosphate binding" evidence="2">
        <location>
            <begin position="215"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="26520" checksum="06EE31971EF2EAD6" modified="2008-04-29" version="1">MSRILLGVNIDHIATLRQARGTSYPDPVHAAAVAEHAGAEGITVHLREDRRHIVDRDIYLLAKTLKTRMNFEMAVTDEMLDIACEVKPAYVCLVPEKREELTTEGGLDVAGQMGKIESAVQRLTDIGVKVSLFIDADKTQIDAAVAVGAPVIEIHTGCYADATNDADQAKELARITEMATYAHGKGLVVNAGHGLHYHNVKPIAAIPELYELNIGHAIIARAAIDGLATAVKDMKQLMNEGRRGE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI71</accession>
    <name>RL19_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplS</name>
        <name type="ordered locus">Swoo_1257</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323895.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI71"/>
    <dbReference type="SMR" id="B1KI71"/>
    <dbReference type="STRING" id="392500.Swoo_1257"/>
    <dbReference type="EnsemblBacteria" id="ACA85549">
        <property type="protein sequence ID" value="ACA85549"/>
        <property type="gene ID" value="Swoo_1257"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1257"/>
    <dbReference type="eggNOG" id="COG0335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103507_2_2_6"/>
    <dbReference type="OMA" id="TITVYYE"/>
    <dbReference type="OrthoDB" id="1698718at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000193886" description="50S ribosomal protein L19">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <sequence length="117" mass="13337" checksum="E3E080CBA786922B" modified="2008-04-29" version="1">MNNIIKMLNEEQMKKDVPEFGAGDTVVVKVRVVEGGKERLQAFEGVVIAKRNRGVHSAFTVRKISNGEGVERAFQTHSPIISDIEVKRRGRVRRAKLYYLRERSGKSARIREKLSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA3</accession>
    <name>B1KIA3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c-type protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2678</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="10">Binds 4 heme groups per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9">Binds 4 heme groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NapC/NirT/NrfH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325294.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2678"/>
    <dbReference type="EnsemblBacteria" id="ACA86954">
        <property type="protein sequence ID" value="ACA86954"/>
        <property type="gene ID" value="Swoo_2678"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2678"/>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096753_2_0_6"/>
    <dbReference type="OMA" id="CHEMQAN"/>
    <dbReference type="OrthoDB" id="1683334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019333">
        <property type="term" value="P:denitrification pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024717">
        <property type="entry name" value="NapC/NirT/NrfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011885">
        <property type="entry name" value="NO3Rdtase_cyt_c_NapC/NirT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000013">
        <property type="entry name" value="4_hem_cytochrm_NapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02161">
        <property type="entry name" value="napC_nirT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_NNT" evidence="13">
        <location>
            <begin position="19"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="10">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="10">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="10">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="10">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="10">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="10">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000013-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000013-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="199" mass="22533" checksum="1B3C6AA37222EF6E" modified="2008-04-29" version="1">MIAKLLSILKTGWTVLRKPSVHYSLGFLTLGGFVAGVIFWGGFNTALEVTNQEAFCIGCHEMENNVYEELKTTIHFTNRSGVRATCPDCHVPHNWTDKIARKMQASKEVWGKIFGTINTRDKFEAKRRELAEHEWARLKANDSLECRNCHNFDYMDFTRQSSRAAKMHSTSLASGEKTCIDCHKGIAHHLPDMKGVPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB4</accession>
    <name>B1KIB4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fatty acid metabolism regulator protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fadR</name>
        <name evidence="11" type="ordered locus">Swoo_2689</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Multifunctional regulator of fatty acid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325305.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2689"/>
    <dbReference type="EnsemblBacteria" id="ACA86965">
        <property type="protein sequence ID" value="ACA86965"/>
        <property type="gene ID" value="Swoo_2689"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2689"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_6"/>
    <dbReference type="OMA" id="WETAGPN"/>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019217">
        <property type="term" value="P:regulation of fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00696">
        <property type="entry name" value="HTH_FadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014178">
        <property type="entry name" value="FA-response_TF_FadR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028374">
        <property type="entry name" value="FadR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43537:SF10">
        <property type="entry name" value="PTHR43537:SF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07840">
        <property type="entry name" value="FadR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02812">
        <property type="entry name" value="fadR_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0010">Activator</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="10">
        <location>
            <begin position="20"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="249" mass="28145" checksum="59B62F9EC90978EF" modified="2008-04-29" version="1">MTIVQKAPTVAKNKDIIEAKGPASFAEKYIVRSIWEEKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNDIWETSGLNVLETIADLNPAGEPVLLEQLLSARTNISAIYFKGAVRHNPEKVLEALKEITQLDNDPKAYVEFDYQLHHTLAYNSGNPLYVLILNGFKGLYSRVGQDYFAIDKARELAYEFYEALQQLAEEKNHNAIPALMRSYGINSGKVWQRFKSSQAQLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIH5</accession>
    <name>B1KIH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2750</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325362.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="SMR" id="B1KIH5"/>
    <dbReference type="STRING" id="392500.Swoo_2750"/>
    <dbReference type="EnsemblBacteria" id="ACA87026">
        <property type="protein sequence ID" value="ACA87026"/>
        <property type="gene ID" value="Swoo_2750"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2750"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_20_6"/>
    <dbReference type="OMA" id="PFGTICM"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="78"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="152"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="236"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="4">
        <location>
            <begin position="380"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="637" mass="73254" checksum="3EB4A2E566A387AD" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY2</accession>
    <name>B1KIY2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor SUI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1338</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323976.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1338"/>
    <dbReference type="EnsemblBacteria" id="ACA85630">
        <property type="protein sequence ID" value="ACA85630"/>
        <property type="gene ID" value="Swoo_1338"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1338"/>
    <dbReference type="eggNOG" id="COG0023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082805_4_0_6"/>
    <dbReference type="OMA" id="KSKCGVG"/>
    <dbReference type="OrthoDB" id="1752091at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037511">
        <property type="entry name" value="Transl_init_SUI1_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01158">
        <property type="entry name" value="SUI1_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="40"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="11882" checksum="977058D33EE19922" modified="2008-04-29" version="1">MKNDSNVTLVYSTDVGRIAPEKEVQEAPQGDGIVRIHKDSKGRKGKGVSVIKGLALSEKELKALAQKLKKQCGCGGTVKEFTIEVQTDNREQLKTLLEKLNYQVKLAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIZ5</accession>
    <name>B1KIZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">BCCT transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1351</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323989.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85643">
        <property type="protein sequence ID" value="ACA85643"/>
        <property type="gene ID" value="Swoo_1351"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1351"/>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010118_5_0_6"/>
    <dbReference type="OMA" id="WAIAWAP"/>
    <dbReference type="OrthoDB" id="1217683at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="507" mass="55366" checksum="A92FC19EBF64DBBF" modified="2008-04-29" version="1" precursor="true">MNRKPEHLNTSPAPIKHRISKEKIGFISCLLLAATFLLFPGTAVTFAASISDYAIKEYGLGFIVFPSLLVILSLLIAFTPFGKVRLGGWDEKPEFGFISWTAMLFAAGMGSGLIFWGVAEPIVHFAHPPSFVADTPLTSNVEDAKDTALALTYFHWGVHAWAVYAISGLVMAWFAFNRGRAMTISASFTDKAKGGRFQVFDFLAVIAVIFGVAGTLANTIALVQSGLQQVLPWDIAGLIFRLVLLMAIALAFTLSSTLGLDRGIKQMSLFNLLFVIAILLVVVSIVDPFAVAETLVTSTVSYISLLPSLSFTIDPSSRAWSEGWSIIYFVWWIAWAPFVGPFIARISKGRTVRQYLLCTIFVPTLTTIVWFSAFGGSVFEMSILDDVIAATNSDVTYGLFTFFDAIPYGKILTYSAILLLVTFVITSADSAIYVSGMLTGSSQLGSKLMWSLTLVAITIALLLKNDIELNKQIAILGAVPFTLILMAQTCILLKEMFNHKRVVDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ27</accession>
    <name>B1KJ27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325383.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2771"/>
    <dbReference type="EnsemblBacteria" id="ACA87047">
        <property type="protein sequence ID" value="ACA87047"/>
        <property type="gene ID" value="Swoo_2771"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2771"/>
    <dbReference type="eggNOG" id="ENOG502ZYVF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110723_0_1_6"/>
    <dbReference type="OMA" id="WLQAGWW"/>
    <dbReference type="OrthoDB" id="1989155at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021306">
        <property type="entry name" value="DUF2878"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11086">
        <property type="entry name" value="DUF2878"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="18990" checksum="EC691D7600AA2DE6" modified="2008-04-29" version="1">MKRFWLINLVLFQATWFVSAIYTDTAWPYLIAIFLLHLLLSPTVKEDIRLLILLPIGVAVDKVLIDLGVFHTSAEVFPLWLILIWVMFIISFNHSLKWLMAMPLVLSALIGAIAGPLSYRLGAELGALEWGVAELNGLLILAAVWAGLLPSLVIGYRHLRLDFALDKKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI3</accession>
    <name>B1KJI3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1364"/>
    <dbReference type="EnsemblBacteria" id="ACA85656">
        <property type="protein sequence ID" value="ACA85656"/>
        <property type="gene ID" value="Swoo_1364"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1364"/>
    <dbReference type="eggNOG" id="COG3153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120018_2_0_6"/>
    <dbReference type="OMA" id="DYCFAYA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14624" checksum="2F39703F9DAEC7F4" modified="2008-04-29" version="1">MPYARLTKKERIAVLLEEKGTAEVAVESEVIAAVRLRPIGLYTLVTGMLIHPQHRGKGLGHTLMRGINNEMTDEYTFIFSLPHLVSFYQQHGFEKCQTPPNDIGQLFNRYHSEDKPLSLLAFKRKTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJS4</accession>
    <name>B1KJS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324093.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1459"/>
    <dbReference type="EnsemblBacteria" id="ACA85747">
        <property type="protein sequence ID" value="ACA85747"/>
        <property type="gene ID" value="Swoo_1459"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1459"/>
    <dbReference type="HOGENOM" id="CLU_1427111_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21988" checksum="6A952A2EEE3C6D64" modified="2008-04-29" version="1">MDIVYSNETIRVDEILSEHIEGIEVLTIACINNDKSLGFEKEDINKEVMYELLTPDSYIYGPKDKEPTYMSEEFDTLIWKKAGGPCLIFSVVEEQFLEELNRLKMYKKNELKAKLKKIDFSEEQPLLQKVYSAANACLDSGSLKKLLSFCRNITIWRFGDLGLYCHVLSTDVNVEKFIPRGRMVEALPEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT0</accession>
    <name>B1KJT0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2842</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325453.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2842"/>
    <dbReference type="EnsemblBacteria" id="ACA87117">
        <property type="protein sequence ID" value="ACA87117"/>
        <property type="gene ID" value="Swoo_2842"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2842"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088255_1_0_6"/>
    <dbReference type="OMA" id="QVHGNIF"/>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001488">
        <property type="entry name" value="Tdi_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764974" description="Thiol:disulfide interchange protein" evidence="6">
        <location>
            <begin position="26"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="14"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="5">
        <location>
            <begin position="56"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001488-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="23304" checksum="5167F904EF7E5376" modified="2008-04-29" version="1" precursor="true">MRLITNPLMALLLLFTALLSMNVDANPYVEGVDYTQVSGIPESSTPVVREFFSYNCPHCYRQDPLFEETEALLKGKVEFARTPIGAGRTSWILSQEAYYLAEKFKMASQLHGNIFKRIHEKEGAFTRKEQLVEYFVKQGVKREDVDKAMSSADASLAISNYDAQAQLAGIRGVPSLLVNGKYLISSKHRTAEELAELVTYLSGLEDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT7</accession>
    <name>B1KJT7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smc</name>
        <name evidence="6" type="ordered locus">Swoo_2849</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325460.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2849"/>
    <dbReference type="EnsemblBacteria" id="ACA87124">
        <property type="protein sequence ID" value="ACA87124"/>
        <property type="gene ID" value="Swoo_2849"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2849"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_2_2_6"/>
    <dbReference type="OMA" id="HNKIAME"/>
    <dbReference type="OrthoDB" id="1149850at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="5">
        <location>
            <begin position="3"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="170"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="678"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="790"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1133" mass="127154" checksum="BECD2854E5761C13" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJU5</accession>
    <name>B1KJU5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Cysteine synthase</fullName>
            <ecNumber evidence="5 11">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_2857</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="5 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325468.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2857"/>
    <dbReference type="EnsemblBacteria" id="ACA87132">
        <property type="protein sequence ID" value="ACA87132"/>
        <property type="gene ID" value="Swoo_2857"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2857"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_1_2_6"/>
    <dbReference type="OMA" id="FWDSGER"/>
    <dbReference type="OrthoDB" id="1033353at2"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="11"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="177"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="322" mass="34444" checksum="7DE77D5E4541D999" modified="2008-04-29" version="1">MSKIFEDNSHTIGNTPLVRLKRVSPGNVLAKVEARNPSFSVKCRIGANMIWDAEKKGTLTQDKELIEPTSGNTGIALAYVAAARGYKLTLTMPNTMSLERRKLLKALGANLVLTEGAKGMKGAIDKAEEIRQSAPEKYVLLQQFDNPANPEIHEKTTGPEIWNDTDGEVDVVVAGVGTGGTITGVSRYIKNAQGKAITSVAVEPVDSPVIQQTISGVEVKPGPHKIQGIGAGFIPGNLDLEMIDRVEAVSNEESIEMAQRLMKEEGILVGISSGAAVVAANRIAALPEFKDKNIVVILPSAAERYLSSILFQGEFGDAENIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJY2</accession>
    <name>B1KJY2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2896</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325505.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2896"/>
    <dbReference type="EnsemblBacteria" id="ACA87169">
        <property type="protein sequence ID" value="ACA87169"/>
        <property type="gene ID" value="Swoo_2896"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2896"/>
    <dbReference type="eggNOG" id="COG3127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009475_2_0_6"/>
    <dbReference type="OMA" id="LIMWRLS"/>
    <dbReference type="OrthoDB" id="127265at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="693"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="748"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="782"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="281"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="821" mass="90250" checksum="B493CB0B5C6433E2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK06</accession>
    <name>B1KK06_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">7TM domain sensor diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2920"/>
    <dbReference type="EnsemblBacteria" id="ACA87193">
        <property type="protein sequence ID" value="ACA87193"/>
        <property type="gene ID" value="Swoo_2920"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2920"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_105_4_6"/>
    <dbReference type="OMA" id="FRIDSHE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011623">
        <property type="entry name" value="7TMR_DISM_rcpt_extracell_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011622">
        <property type="entry name" value="7TMR_DISM_rcpt_extracell_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07695">
        <property type="entry name" value="7TMR-DISM_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07696">
        <property type="entry name" value="7TMR-DISMED2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="483"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="623" mass="70965" checksum="9B8FBC5DEA97FD69" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF1</accession>
    <name>B1KKF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324137.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1503"/>
    <dbReference type="EnsemblBacteria" id="ACA85791">
        <property type="protein sequence ID" value="ACA85791"/>
        <property type="gene ID" value="Swoo_1503"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1503"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089893_3_0_6"/>
    <dbReference type="OMA" id="CHTCRYL"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="21205" checksum="8A6C364474B0D5C8" modified="2008-04-29" version="1">MNTLIIQQLIERLSSLLRSESRHQLAEFGLQPVQFDALCYLASCNRYSDTPKAVTEFLGLTKGTVSQSIKILESKGLVLKQADKNDKRVTHLGVSQQGELLVERLMPANMLKLACHNSSEDELGKTVEMLRTMLRQVQDANGFKSFGQCQTCSHNQKRDDGSYFCGLTQEALSAQDILLICVEHEKRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKM9</accession>
    <name>B1KKM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325582.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2975"/>
    <dbReference type="EnsemblBacteria" id="ACA87246">
        <property type="protein sequence ID" value="ACA87246"/>
        <property type="gene ID" value="Swoo_2975"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2975"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_6"/>
    <dbReference type="OMA" id="GVSQHIK"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="33482" checksum="80008E9A811A4927" modified="2008-04-29" version="1">MLNLNWLHTFKTLIEVGHFTHTAEKLYMTQPGVSQHIKKLEQACGHSLIKREKKSFEITEQGQRVYDYAVQVALTQAKLLDSLHFDDPYAGTCKLSCSGALALQLYPALLTLQINYPELVTHLEAAPNDKILNDIQNGKVDIGLVTQAPSANGFHVERIGTEPLCLILPLRYKDKVLTAASLQECGLVKHPDAEHYLSLYFDLCGNSELSKLNIDEIKTVSYVNQLNQILLPISLGIGCTVLPQSVLSNSSYRDKLYISPPKQAVNESLFLVHKRNRQLARRHQTIKNKILEQLKAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL77</accession>
    <name>B1KL77_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MORN variant repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322767.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0117"/>
    <dbReference type="EnsemblBacteria" id="ACA84418">
        <property type="protein sequence ID" value="ACA84418"/>
        <property type="gene ID" value="Swoo_0117"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0117"/>
    <dbReference type="eggNOG" id="COG2849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_362857_0_0_6"/>
    <dbReference type="OMA" id="CKVKYRS"/>
    <dbReference type="OrthoDB" id="1997695at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767454" evidence="1">
        <location>
            <begin position="26"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="769" mass="89334" checksum="59AD5F332A7A7FB9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL85</accession>
    <name>B1KL85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322775.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0125"/>
    <dbReference type="EnsemblBacteria" id="ACA84426">
        <property type="protein sequence ID" value="ACA84426"/>
        <property type="gene ID" value="Swoo_0125"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0125"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_6"/>
    <dbReference type="OMA" id="RWMLGYD"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="374" mass="42075" checksum="9F996E9136EA13DE" modified="2008-04-29" version="1">MKILIVGAGIAGLALARRLDQLQQKYTLIERSPGWSQDGAGICLPANAVAGLEKLGLKDELLQLSYAVQKIKYVKPNGHLLSSASLLTPPFNDQPFLALPRAKLLALLRKDMESKVTFNTSPRNIEQLDKGVRVTFSDSRIEEFDCVIGADGINSQVRELTFNQPELEDLQVTNWRFLIDQPTAGLQPTYYLGSDSFFMRYPMPDNKVYCYAHVLDKGHQWTKLQDKQWLLKRFKGFEDKVVEAIQAVACDEDIIPGRLQSVVSREVYSGSVLLIGDALHGCPPALQQGVGMGLEDVHCLADLLDKHQDLDTIFNLFKQQRLERISWVIDESNRIIKLASKGRTFLGRVIRNFVVRKGGPANVNGWRKLLLWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA9</accession>
    <name>B1KLA9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ancillary SecYEG translocon subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1546</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the YfgM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324180.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1546"/>
    <dbReference type="EnsemblBacteria" id="ACA85834">
        <property type="protein sequence ID" value="ACA85834"/>
        <property type="gene ID" value="Swoo_1546"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1546"/>
    <dbReference type="eggNOG" id="COG2976">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084785_0_0_6"/>
    <dbReference type="OMA" id="RFFANNG"/>
    <dbReference type="OrthoDB" id="1926596at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018704">
        <property type="entry name" value="TPR_21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026039">
        <property type="entry name" value="YfgM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38035">
        <property type="entry name" value="PTHR38035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09976">
        <property type="entry name" value="TPR_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006170">
        <property type="entry name" value="YfgM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_21" evidence="5">
        <location>
            <begin position="15"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="21855" checksum="7B3DADC94A16E430" modified="2008-04-29" version="1">MEIYSTEEQQVDAIKQFWKDYGTSIVVGAVVGLGGLFGWNYYSEHKITQAESASEAFQAMSAPALDEAGMLAAAETFAKEHSQKGYQSLLSLIVAKAAVESGDLEKAETTLKSVIASAADTSLVMVATIRLARVQAEQGQIATAITTLEQVSDPAFTAQRDELKGDFLVRKGDAEQAKAAYQAAVDNGGATASPALQMKLDNLNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG0</accession>
    <name>B1KLG0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Basal-body rod modification protein FlgD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1599</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Required for flagellar hook formation. May act as a scaffolding protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FlgD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324231.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1599"/>
    <dbReference type="EnsemblBacteria" id="ACA85885">
        <property type="protein sequence ID" value="ACA85885"/>
        <property type="gene ID" value="Swoo_1599"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1599"/>
    <dbReference type="eggNOG" id="COG1843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047535_0_2_6"/>
    <dbReference type="OMA" id="STYAHVT"/>
    <dbReference type="OrthoDB" id="709873at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005648">
        <property type="entry name" value="FlgD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025965">
        <property type="entry name" value="FlgD_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025963">
        <property type="entry name" value="FLgD_Tudor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03963">
        <property type="entry name" value="FlgD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13860">
        <property type="entry name" value="FlgD_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13861">
        <property type="entry name" value="FLgD_tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FLgD_tudor" evidence="8">
        <location>
            <begin position="128"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="FlgD_ig" evidence="7">
        <location>
            <begin position="155"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="28007" checksum="CB08BC009B5F9FDB" modified="2008-04-29" version="1">MSLINPLNSAQNVGGASQTSNQSVAPAQQTASAAQAATQNTEQTSTTGNPFIDAIRLPDESSIPEPNNQELTQEDFFSLLSQQLSMQDPFKPVDNDQMIAQMASFSTVDGINNLNDEIVNLNTVMTSSQALQASGLVGQKVLIPSDTGHVSAEGRELKGIISTPEAIESITVRVEDDKGQLVKSFTVDGSAGGNVDVAWDGLDKNGEPVADGNYSIKASGKVDGKSEELAVSTYAHVTSVSLGTASTGAILNLRGVGGIKIGDVLAVAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK0</accession>
    <name>B1KLK0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="4">3.1.1.61</ecNumber>
            <ecNumber evidence="4">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cheB</name>
        <name evidence="10" type="ordered locus">Swoo_1639</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CheB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="4"/>
    <dbReference type="EC" id="3.5.1.44" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324271.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1639"/>
    <dbReference type="EnsemblBacteria" id="ACA85925">
        <property type="protein sequence ID" value="ACA85925"/>
        <property type="gene ID" value="Swoo_1639"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1639"/>
    <dbReference type="eggNOG" id="COG2201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_51_0_6"/>
    <dbReference type="OMA" id="YGMPMAV"/>
    <dbReference type="OrthoDB" id="1655418at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000876">
        <property type="entry name" value="RR_chemtxs_CheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="9">
        <location>
            <begin position="179"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4 6">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="372" mass="39680" checksum="4905F0B2751BE959" modified="2008-04-29" version="1" precursor="true">MSIKVLVVDDSSFFRRRVSEIVSKDPDLEVIGTAVNGAEAVKMAAELKPNVITMDIEMPVMDGISAVREIMANTPVPILMFSSLTHDGAKATLDALEAGALDFLPKRFEDIATNKDEAIRLLQQRIKTIGRRRVYKPITPSVTKSAPTPVSRPVTTPVSPRAVSGSVVSPKPSIINRASGKKYRILLIGTSTGGPVALQKILTKFPQNYPHPILLIQHMPAAFTPAFASRLNALCQIEVKEAVSGDQLKAGHAYLAPGGMQMMLERAGTHGRLKIVAGSEDMNYKPSVDITFASVSKVLGKDTLAVILTGMGADGREGSRMLKSSGATIWAQDEASCIVYGMPQAVTAAGLSSQSIGLEQMADAILRESSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM17</accession>
    <name>B1KM17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327221.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4647"/>
    <dbReference type="EnsemblBacteria" id="ACA88897">
        <property type="protein sequence ID" value="ACA88897"/>
        <property type="gene ID" value="Swoo_4647"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4647"/>
    <dbReference type="eggNOG" id="ENOG503168Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1936100_0_0_6"/>
    <dbReference type="OMA" id="ENIPTEC"/>
    <dbReference type="OrthoDB" id="1996345at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15452" checksum="583E2C6F67270DD8" modified="2008-04-29" version="1" precursor="true">MKSLLAIAIIVLFFPLIGCQVSQHKQTSDKNKSSISEPIHKGVYVWGHEVSSYQPCGEHLTYWVTATPASDELNQLSLALSETRNAPYQPIYIEAAIHPIDRNSHPAFSDGFAADYDAIIEISNVYMKLTELPSSCKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM78</accession>
    <name>B1KM78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322840.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0190"/>
    <dbReference type="EnsemblBacteria" id="ACA84491">
        <property type="protein sequence ID" value="ACA84491"/>
        <property type="gene ID" value="Swoo_0190"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0190"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_13_1_6"/>
    <dbReference type="OMA" id="PDETSHE"/>
    <dbReference type="OrthoDB" id="949250at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767201" evidence="3">
        <location>
            <begin position="29"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="5">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="5">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="5">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="5">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="291"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="599" mass="66035" checksum="E6C2F1A78EC2DFFB" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMS2</accession>
    <name>B1KMS2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325786.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3179"/>
    <dbReference type="EnsemblBacteria" id="ACA87450">
        <property type="protein sequence ID" value="ACA87450"/>
        <property type="gene ID" value="Swoo_3179"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3179"/>
    <dbReference type="eggNOG" id="ENOG5033DAR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117647_0_0_6"/>
    <dbReference type="OMA" id="QGFANIK"/>
    <dbReference type="OrthoDB" id="1350287at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025411">
        <property type="entry name" value="DUF4136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13590">
        <property type="entry name" value="DUF4136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766870" description="DUF4136 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4136" evidence="2">
        <location>
            <begin position="44"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20408" checksum="816E0BA4A8F00788" modified="2008-04-29" version="1" precursor="true">MIRQICCLLLLSTLTACTASEAVKPSPQRTTMVATGDLGFLSTQTRHFAWHPTLAKVVADERVESDQVIGNMQQALKKALEAKGYQLVSRQQSPDLLVGFGLTLSSDMSDSEILQKTGLVPGLSTFGVDMNKYEKGSVLVALFEPQSPEPVWRALGQGFTDFERDGAKRQQGFNEFISVMLTAIPAI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ0</accession>
    <name>RPOB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="1">RNAP subunit beta</shortName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpoB</name>
        <name type="ordered locus">Swoo_4697</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327266.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMZ0"/>
    <dbReference type="SMR" id="B1KMZ0"/>
    <dbReference type="STRING" id="392500.Swoo_4697"/>
    <dbReference type="EnsemblBacteria" id="ACA88947">
        <property type="protein sequence ID" value="ACA88947"/>
        <property type="gene ID" value="Swoo_4697"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4697"/>
    <dbReference type="eggNOG" id="COG0085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_4_3_6"/>
    <dbReference type="OMA" id="FMTWEGY"/>
    <dbReference type="OrthoDB" id="9601at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000141738" description="DNA-directed RNA polymerase subunit beta">
        <location>
            <begin position="1"/>
            <end position="1343"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <sequence length="1343" mass="149895" checksum="741758A4DFE20EA5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN11</accession>
    <name>B1KN11_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327286.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4718"/>
    <dbReference type="EnsemblBacteria" id="ACA88968">
        <property type="protein sequence ID" value="ACA88968"/>
        <property type="gene ID" value="Swoo_4718"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4718"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_4_0_6"/>
    <dbReference type="OMA" id="PGYFASK"/>
    <dbReference type="OrthoDB" id="1831818at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="20648" checksum="2EC92FACE4327853" modified="2008-04-29" version="1">MNNKKPEILGAEIVAQSRLFKIEQVHLKFSNQVERHYERMKGNNRGAVMVVPVLNRDTLLLGREYAAGTHSYELGFPKGLIDPGEEAHEAANRELQEEIGYGSKKLTHLMELSLAPGYFASKMQIFIAEDLYESQLEGDEPEPIELAPWPIEKWQSLLEREDFSESRSVSALFLALKYLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN23</accession>
    <name>B1KN23_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_4730</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the GSP H family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327297.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4730"/>
    <dbReference type="EnsemblBacteria" id="ACA88980">
        <property type="protein sequence ID" value="ACA88980"/>
        <property type="gene ID" value="Swoo_4730"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4730"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111963_0_0_6"/>
    <dbReference type="OMA" id="YVMFNAF"/>
    <dbReference type="OrthoDB" id="1990712at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002416">
        <property type="entry name" value="T2SS_protein-GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00885">
        <property type="entry name" value="BCTERIALGSPH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01708">
        <property type="entry name" value="typeII_sec_gspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="GspH" evidence="12">
        <location>
            <begin position="44"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA88980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="21845" checksum="600737E49A87CB85" modified="2008-04-29" version="1" precursor="true">MRTLHQKGFTLMEVLLVILLMGLAASAVTMSMSGADKKRELEKTAQQFMAATEMVLDETVLSGHFIGIVIEDDSYKYVVYDEAKWKPLTQDRILGEREMEPGVRIDLVLDGLPLVQDDEEQDSWFEEPLIEKSEEDKKKFPEPQILLFPSGEMSAFELMFVSEDETGKEVEALVVGDALGRMTQGRDHGFDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN59</accession>
    <name>B1KN59_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0255</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84556">
        <property type="protein sequence ID" value="ACA84556"/>
        <property type="gene ID" value="Swoo_0255"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0255"/>
    <dbReference type="eggNOG" id="COG3148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066458_2_1_6"/>
    <dbReference type="OMA" id="FLMHPKE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039262">
        <property type="entry name" value="DTWD2/YfiP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392">
        <property type="entry name" value="PTHR21392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="5">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19592" checksum="A9BAC1D27DCECE19" modified="2008-04-29" version="1">MQVSTELIVLQDPSEVGHAKNSVRLMELVIPETQVYVGETPQDFQALRHYLNTCGKPVFLVYPSDSSSDVAETSFTEQAVLLLLDGTWRKAYKLLQLNPWLQDYPALHLDLTSASNYKIRKASRADSLSTLEAAAMMLKAIEPELQITPLTNALDAMVQQRIRSMPPAVRKRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB2</accession>
    <name>B1KNB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0308"/>
    <dbReference type="EnsemblBacteria" id="ACA84609">
        <property type="protein sequence ID" value="ACA84609"/>
        <property type="gene ID" value="Swoo_0308"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0308"/>
    <dbReference type="eggNOG" id="ENOG5033YKJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1668208_0_0_6"/>
    <dbReference type="OMA" id="WRNENFR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="18902" checksum="1B5221C934B4ACA4" modified="2008-04-29" version="1">MATSQEQWTQAFEILEHFERKLIEPKEFNWTYFKETTGVSKATLWRNENFRSEHARISKLIKKYKEKNADYDLEQSILSVKDHEILELKKQIFELEKKLGRERERLAYAAIIARQSNIDPNRFMEESPLLKAQANAKKNEINTPKIDDKALDRFRKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNC0</accession>
    <name>B1KNC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0316"/>
    <dbReference type="EnsemblBacteria" id="ACA84617">
        <property type="protein sequence ID" value="ACA84617"/>
        <property type="gene ID" value="Swoo_0316"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0316"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049290_1_0_6"/>
    <dbReference type="OMA" id="PFTDAQY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21021" checksum="A146EC4C554CCD56" modified="2008-04-29" version="1">MVGQNPIKLNAGWVQSGVRECLSPHFNARPKGEVSLLVIHNISLPAGCFGTPYVDQLFQGCLDLEADISFGELKGLEVSAHFMIRRDGEIVQYVSCDERAWHAGVSEFQGRQGCNDFAIGIELEGTDLIAYSELQYQALLRLTLALFNAYPMLNMDRLVGHSDIAPGRKTDPGDSFDWLKYRDGLTQALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNH6</accession>
    <name>B1KNH6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CbiA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324399.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1769"/>
    <dbReference type="EnsemblBacteria" id="ACA86053">
        <property type="protein sequence ID" value="ACA86053"/>
        <property type="gene ID" value="Swoo_1769"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1769"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037612_5_4_6"/>
    <dbReference type="OMA" id="YTDIPAM"/>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="24800" checksum="AD0644A553680D33" modified="2008-04-29" version="1">MIILVGGEKGGAGKSCLAQNVAVHITRKFQANVLMVDCDPQRTTSDWIQARNEDPELPTINCIQLYGKIRNDLLSQDERFDYVIVDCGGQDNLAMRAAMSVATYVILPLRPKRRDLKTLPHMEDMLSTCKMVNPKMVATIVMTQCPSLPSQYKRILEAKEVVQSFGLRVLNSVTFNRNIYDDSEEQGASVMEIEPEGKAATEIVAIADEIFAIEPENSYELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS4</accession>
    <name>B1KNS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325868.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3262"/>
    <dbReference type="EnsemblBacteria" id="ACA87532">
        <property type="protein sequence ID" value="ACA87532"/>
        <property type="gene ID" value="Swoo_3262"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3262"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018914_1_0_6"/>
    <dbReference type="OMA" id="GMEVVRI"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764696" evidence="1">
        <location>
            <begin position="25"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="611" mass="69293" checksum="D0105FE7E9B4FD6F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX8</accession>
    <name>B1KNX8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327326.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4760"/>
    <dbReference type="EnsemblBacteria" id="ACA89009">
        <property type="protein sequence ID" value="ACA89009"/>
        <property type="gene ID" value="Swoo_4760"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4760"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_0_1_6"/>
    <dbReference type="OMA" id="ICAYTAT"/>
    <dbReference type="OrthoDB" id="1930882at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="88"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="30940" checksum="945A0E4BFEF25DBB" modified="2008-04-29" version="1">MTSLVEVKRKESSFDFNTQRNGFQLLVFSLFVLHIVTLNSETNLYLFNLINGLSDFFPLWLLAIVTDLGHGSTLGTLVLCYLTLRPEMTIRVIGASILSLILVPLLKQYFEAPRPADVLDSLNIIGEVRHHLSFPSGHTATAFLFAGTIFLAVNCNKLKFMLIMLASLVGISRVMVGAHWPIDVVMGAILGLICAYTATKFIPLYSLEPKVRGLSYLILFLLLVGSEIGKVMDPDLLWQTLVLRWSVFIFCGALIVRYALANSELLFASIPTVPSSTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY4</accession>
    <name>B1KNY4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferritin</fullName>
            <ecNumber evidence="1">1.16.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Iron-storage protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide</text>
            <dbReference type="Rhea" id="RHEA:11972"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:78619"/>
            <dbReference type="EC" id="1.16.3.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ferritin family. Prokaryotic subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327332.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4766"/>
    <dbReference type="EnsemblBacteria" id="ACA89015">
        <property type="protein sequence ID" value="ACA89015"/>
        <property type="gene ID" value="Swoo_4766"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4766"/>
    <dbReference type="eggNOG" id="COG1528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065681_1_0_6"/>
    <dbReference type="OMA" id="CEDKGFE"/>
    <dbReference type="OrthoDB" id="1890523at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01055">
        <property type="entry name" value="Nonheme_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041719">
        <property type="entry name" value="Ferritin_prok"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="PTHR11431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0409">Iron storage</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="20004" checksum="C29359E8B1F4D2FC" modified="2008-04-29" version="1">MLAQTMIDQLNAQINVEFFSSNLYLQMSAWCEDKGFEGAAKFMRAHADEEMQHMHRLFTYVSETGGMPLLGAIEAPQAEFNSLLALFEYTYEHEQMITRKINDLAHAAFTNQDYSTFNFLQWYVSEQHEEEKLFKSVVDKIRLVGEDGKALFFVDKDLAQMAVSESESVMTGEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP14</accession>
    <name>B1KP14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4796"/>
    <dbReference type="EnsemblBacteria" id="ACA89045">
        <property type="protein sequence ID" value="ACA89045"/>
        <property type="gene ID" value="Swoo_4796"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4796"/>
    <dbReference type="eggNOG" id="COG3296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104196_0_2_6"/>
    <dbReference type="OMA" id="LIVWLMK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019109">
        <property type="entry name" value="DUF4870"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09685">
        <property type="entry name" value="DUF4870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="130" mass="14473" checksum="2B132E4A3FFAEB9F" modified="2008-04-29" version="1">MTEEAQVEVQEDQQALSQDERNMGIAVHASSFAGYIIPFGSILGPLIVWLMKRDEIAFVDECGRNCLNFKISLMIYMMISAILMFVGIGFILIGILAVADIVFTIIAAMKASEGISYQYPMSIKFLKPRN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP64</accession>
    <name>ARLY_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Argininosuccinate lyase</fullName>
            <shortName evidence="1">ASAL</shortName>
            <ecNumber evidence="1">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argH</name>
        <name type="ordered locus">Swoo_0333</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322983.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP64"/>
    <dbReference type="SMR" id="B1KP64"/>
    <dbReference type="STRING" id="392500.Swoo_0333"/>
    <dbReference type="EnsemblBacteria" id="ACA84634">
        <property type="protein sequence ID" value="ACA84634"/>
        <property type="gene ID" value="Swoo_0333"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0333"/>
    <dbReference type="eggNOG" id="COG0165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_2_3_6"/>
    <dbReference type="OMA" id="KKNPDVF"/>
    <dbReference type="OrthoDB" id="751464at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0055">Arginine biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000089117" description="Argininosuccinate lyase">
        <location>
            <begin position="1"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <sequence length="456" mass="50044" checksum="98D7FD635DD60730" modified="2008-04-29" version="1">MALWGGRFSQESSALFKLFNDSLPVDYRLVEQDIVGSIAWAAAITQVGILSQDECEKLQQALKELLSEVEGNPELILASGAEDIHSFVEQSLIAKVGDLGKKLHTGRSRNDQVATDLKLWCKKEGQQQLVLLAKLREALLALAERELDAVMPGYTHLQRAQPVAFGHWCLAYVEMFERDISRLEDALKRADTCPLGTGALAGTAYPMDRYKLAESLGFASPTLNSLDTVSDRDHVVEICSDASISMMHLSRMAEDLIFFNSGEAGFIDLDDEVTSGSSLMPQKKNPDALELIRGKTGRVYGSLIGILTTMKALPLAYNKDMQEDKEGLFDVMDSWSICLEMAALVLSGLKVNRENTLKAAQQGYANSTELADYLVAKGMPFREAHHVVGEVVVHAISEQKPLEDFALEQLQSFASIIEQDVYDCLTIESCLAKREALGGTALPQVQSALAAKKVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP76</accession>
    <name>B1KP76_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322995.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0345"/>
    <dbReference type="EnsemblBacteria" id="ACA84646">
        <property type="protein sequence ID" value="ACA84646"/>
        <property type="gene ID" value="Swoo_0345"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0345"/>
    <dbReference type="eggNOG" id="ENOG5033BGP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162053_0_0_6"/>
    <dbReference type="OMA" id="PSNRCAS"/>
    <dbReference type="OrthoDB" id="1724605at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767266" evidence="1">
        <location>
            <begin position="31"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="117" mass="12594" checksum="A1DC7E166DF12429" modified="2008-04-29" version="1" precursor="true">MKSSKKLIVGAKPAAFLATSAIFIALTAVGAQNLSSSDSESACVCSKESTTSYNSSLPTSHPGNRCARQSQELNWANWFSGNSRSNQLHFVDLLELLHGHQDSPVDEVSLSNQKNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPK1</accession>
    <name>B1KPK1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protease HtpX</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Heat shock protein HtpX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">htpX</name>
        <name evidence="14" type="ordered locus">Swoo_1870</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M48B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324500.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1870"/>
    <dbReference type="MEROPS" id="M48.002"/>
    <dbReference type="EnsemblBacteria" id="ACA86154">
        <property type="protein sequence ID" value="ACA86154"/>
        <property type="gene ID" value="Swoo_1870"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1870"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042266_1_0_6"/>
    <dbReference type="OMA" id="AVCCTEG"/>
    <dbReference type="OrthoDB" id="1918093at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00188">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022919">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="13">
        <location>
            <begin position="73"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="286" mass="30565" checksum="B21555435BB753B3" modified="2008-04-29" version="1" precursor="true">MRIFLLIATNMAILLVASIVMSLLGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITAPRDNTERWLVETVARQAEQAGIKMPEVAIYQSEELNAFATGPSKDNALVAVSSGLLYGMSQDEIEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIIDNFVSSNDEEGEGLGMFAYMGVVFVLDMLFGILASMIVAYFSRIREFKADEGAAKLAGKEKMIAALERLRQGPATGAMPAQMSALGINGKKSMSELMMSHPPLEKRIAALRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPP8</accession>
    <name>B1KPP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEBP family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324547.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1917"/>
    <dbReference type="EnsemblBacteria" id="ACA86201">
        <property type="protein sequence ID" value="ACA86201"/>
        <property type="gene ID" value="Swoo_1917"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1917"/>
    <dbReference type="eggNOG" id="COG1881">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083918_2_0_6"/>
    <dbReference type="OMA" id="LRWEGFP"/>
    <dbReference type="OrthoDB" id="1150223at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00865">
        <property type="entry name" value="PEBP_bact_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005247">
        <property type="entry name" value="YbhB_YbcL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30289">
        <property type="entry name" value="PTHR30289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="SSF49777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00481">
        <property type="entry name" value="TIGR00481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764728" evidence="1">
        <location>
            <begin position="21"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="18671" checksum="6BBDA0C7B63BD1E5" modified="2008-04-29" version="1" precursor="true">MKLKTLIILLAGVASFSSQALEISSKDIHEGQLMRSKFEFSGMGCSGGNVSPQLSWSNAPKGTKSFAITVFDPDAPTGSGWWHWTVLNLPASTTHLERGAKITKGLETRTDFGKPGFGGACPPEGDGMHRYQFTVWALPQEKVDLPADISPAVVGFTLNSMALDKAVLTATFVR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS4</accession>
    <name>CSRA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translational regulator CsrA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Carbon storage regulator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">csrA</name>
        <name type="ordered locus">Swoo_3338</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CsrA/RsmA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325942.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPS4"/>
    <dbReference type="SMR" id="B1KPS4"/>
    <dbReference type="STRING" id="392500.Swoo_3338"/>
    <dbReference type="EnsemblBacteria" id="ACA87607">
        <property type="protein sequence ID" value="ACA87607"/>
        <property type="gene ID" value="Swoo_3338"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3338"/>
    <dbReference type="eggNOG" id="COG1551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164837_2_2_6"/>
    <dbReference type="OMA" id="IHRKEVY"/>
    <dbReference type="OrthoDB" id="2032250at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048027">
        <property type="term" value="F:mRNA 5'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00167">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003751">
        <property type="entry name" value="CsrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036107">
        <property type="entry name" value="CsrA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34984">
        <property type="entry name" value="PTHR34984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02599">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117130">
        <property type="entry name" value="SSF117130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00202">
        <property type="entry name" value="csrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0810">Translation regulation</keyword>
    <feature type="chain" id="PRO_1000097509" description="Translational regulator CsrA">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00167"/>
        </source>
    </evidence>
    <sequence length="65" mass="7112" checksum="FB228A4840AA8FD7" modified="2008-04-29" version="1">MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQSEKAGNSSEGGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPY3</accession>
    <name>B1KPY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction histidine kinase, LytS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327413.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4847"/>
    <dbReference type="EnsemblBacteria" id="ACA89096">
        <property type="protein sequence ID" value="ACA89096"/>
        <property type="gene ID" value="Swoo_4847"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4847"/>
    <dbReference type="eggNOG" id="COG2972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020473_1_1_6"/>
    <dbReference type="OMA" id="HFMYNSL"/>
    <dbReference type="OrthoDB" id="1031920at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="190"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="43745" checksum="8FBA177B931CC4CC" modified="2008-04-29" version="1">MPYAMSSTVEPNWFVNYYRNSRNTSKSYRAAMLIMFWLHFILTWSVMLSLIEVPDRHYNDIILRSFLEASLLVAVCHCLIRPYLRMNLIGSSVDIKGSLKGLLYVALISFIYFLSSYSMGQMSFLKGTDISQIQVITQKGELGGEVTLLAIAIIGTLESFATLFLWSVAYLVWQFHKNKKELQVQVNESQIQQLTNQLSPHFLFNTLNSIRALIFADQEKAAEVITLLSDLLRNQMQSQIQIQSTLEQDWLLTSKYLAIEKVRFDKRLELTVDLDESTLLEQIPTLTLLTLAENAIKHGISTSSKPGFIHIKSQTITPNMWRLSVTNSVYSPKDQPGTRVGLHNVKKRLELMFARQYKFASALDNEQFTVSMELPHVKSTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ47</accession>
    <name>B1KQ47_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-polyprenyl-6-hydroxyphenol methylase</fullName>
            <ecNumber evidence="1">2.1.1.222</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.64</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiG</name>
        <name evidence="2" type="ordered locus">Swoo_4911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:31411"/>
            <dbReference type="Rhea" id="RHEA-COMP:9550"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:62729"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="EC" id="2.1.1.222"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.222" evidence="1"/>
    <dbReference type="EC" id="2.1.1.64" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327476.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4911"/>
    <dbReference type="EnsemblBacteria" id="ACA89160">
        <property type="protein sequence ID" value="ACA89160"/>
        <property type="gene ID" value="Swoo_4911"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4911"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042432_0_0_6"/>
    <dbReference type="OMA" id="AGEWWRP"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102208">
        <property type="term" value="F:2-polyprenyl-6-hydroxyphenol methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008689">
        <property type="term" value="F:3-demethylubiquinone-9 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="30493" checksum="3FDCD9648DB4FE34" modified="2008-04-29" version="1">MLDKSRLTPRRLAKGLKSHEEIAKFDALAEEWRDPQGKFKHVLAFNLTRLTAIQMMIAEHFKRDLTQDIPFNDLTMLDIGCGVGLLCEPLSKQGAHVTGIDASCYNIDLARQHAEKNNININYQHCLAEDLLAKQPINIANNQSDRIGSKHYDVVLNTEVIEHVEDQQALIKTCCELVKPGGILIMATLNRTIKSYVIGIIGAEYVMRYLPIGTHDWHYFVTPKEINTMISANGLTPITSQGMSFNPFTKQWSITSNTDVNYLSYAYKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM5</accession>
    <name>B1KQM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminodeoxychorismate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324610.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1980"/>
    <dbReference type="EnsemblBacteria" id="ACA86264">
        <property type="protein sequence ID" value="ACA86264"/>
        <property type="gene ID" value="Swoo_1980"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1980"/>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020844_2_1_6"/>
    <dbReference type="OMA" id="VPWTRNE"/>
    <dbReference type="OrthoDB" id="1275805at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008696">
        <property type="term" value="F:4-amino-4-deoxychorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01559">
        <property type="entry name" value="ADCL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017824">
        <property type="entry name" value="Aminodeoxychorismate_lyase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03461">
        <property type="entry name" value="pabC_Proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="271" mass="29911" checksum="126916CA9C1BA9BB" modified="2008-04-29" version="1" precursor="true">MTQVWVNGVLAKEIDPLDRAIAYGDGLFATMRIAAGEIQFLSAHLARLTQGAKRLGFTWFASQELQSLLKSSALTQVNGCVKLLLSRGVGGRGYAAPDACGINEVLSLYELPQHYAHWQSEGVSLSLSEVKLAKQPRLAGIKHLNRLEQVLIKSTALPSSFDDWLVLDSDSQVVESSMANLFFVKNKTVFTPAISHSGVAGVMREQLIFALVESGYHIDIKQISYADINKFDHCFMTNSLFGLVDVNRIGTINYSKYSLSDRLRNTLQLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR6</accession>
    <name>B1KQR6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Na(+)-translocating NADH-quinone reductase subunit B</fullName>
            <shortName evidence="13">Na(+)-NQR subunit B</shortName>
            <shortName evidence="13">Na(+)-translocating NQR subunit B</shortName>
            <ecNumber evidence="13">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">NQR complex subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">NQR-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nqrB</name>
        <name evidence="15" type="ordered locus">Swoo_3404</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell inner membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the NqrB/RnfD family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326007.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3404"/>
    <dbReference type="EnsemblBacteria" id="ACA87672">
        <property type="protein sequence ID" value="ACA87672"/>
        <property type="gene ID" value="Swoo_3404"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3404"/>
    <dbReference type="eggNOG" id="COG1805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042020_1_1_6"/>
    <dbReference type="OMA" id="WEVVFAK"/>
    <dbReference type="OrthoDB" id="1654433at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00426">
        <property type="entry name" value="NqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010966">
        <property type="entry name" value="NqrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578">
        <property type="entry name" value="PTHR30578"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016055">
        <property type="entry name" value="NADH-UbQ_OxRdtase_B_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01937">
        <property type="entry name" value="nqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 13 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 13 14" id="KW-0288">FMN</keyword>
    <keyword evidence="11 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="4 13 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 13" id="KW-0813">Transport</keyword>
    <keyword evidence="13 15" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="13 14">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR016055-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA87672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="44015" checksum="C072D49897C72352" modified="2008-04-29" version="1">MNSKDNKPDLQEDYYAPGQAMKGYLRSLVIAHGRSTKGKVHVRDAIDVKRTMTMVGLCLLPAILFGLYNLGLQAQLAIASGLSTPDVWQLGLFNLISGGLTEQTGLIGLFLYGLSFYFPIYLTALLVSLFWEVVFAKVRGQELHEGFFVTALLFTLILPVSTPLWIVAMGITFGVVIAKELFGGMGYNFLNPALAGLSFIFFAYPSEVASVGQLVAVDGFSGATALAQTAAGKLSFAEYAWFDAFSDPNWWNAFLGFIPGAIGETSTLALLIGGGLLLLSRLADWRIVAGVMLGMILTAIMFNLIGSAKNELFAMPWTWHLVTGGFALGMMFMATDPVTTSYTRKGKIAYGFLIGFMTVLIRVVNPKMSEGIMLAILFANLWAPIFDYLVAKANIKRRVKRNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU7</accession>
    <name>B1KQU7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326038.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3435"/>
    <dbReference type="EnsemblBacteria" id="ACA87703">
        <property type="protein sequence ID" value="ACA87703"/>
        <property type="gene ID" value="Swoo_3435"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3435"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_14_4_6"/>
    <dbReference type="OMA" id="ANWCWVR"/>
    <dbReference type="OrthoDB" id="1560019at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="86"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="25483" checksum="57665115821BE892" modified="2008-04-29" version="1">MIDLYTAATPNGHKISIALEEMGLEYRVHHLDLMQADQKKPEYLAINPNGRIPAIIDRDNDDFAVFESGAILLYLAEKTGKLLPTNPKKRSQVIQWLMFQMGGVGPMMGQANVFHRYFPEKIPAAIERYQNESRRLFEVMNLQLSDNRYLAGDEYSIADISTWPWVRIYEWSGVDISGLEHLQRWMDELAERKACQIGVITPPPSDLSDKERAEQISKMVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQW6</accession>
    <name>B1KQW6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Recombination-associated protein RdgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rdgC</name>
        <name evidence="7" type="ordered locus">Swoo_3455</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
            <location evidence="2 5">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the RdgC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3455"/>
    <dbReference type="EnsemblBacteria" id="ACA87722">
        <property type="protein sequence ID" value="ACA87722"/>
        <property type="gene ID" value="Swoo_3455"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3455"/>
    <dbReference type="eggNOG" id="COG2974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052038_1_1_6"/>
    <dbReference type="OMA" id="RFDADFT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00194">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007476">
        <property type="entry name" value="RdgC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38103">
        <property type="entry name" value="PTHR38103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04381">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="114"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="37614" checksum="6DC6B1D166ED8610" modified="2008-04-29" version="1">MKYASNLRQDHYLCGLPELSNGLHCAFNFDWALIMWFKNLTVYRFNKPFSVDPEALEKSLEDFTFSPCSSQDISKFGFSNALGKKGISLVHSASGRHLICATKEEKILPGQVIKEALEDKVAQIEAEEDRKLAKKEKDAMKEEIIMTLLPRAFTRRSQIHALIIPEIEMILVDSSSAAKSEELLALLRKALGSLPIIPLSFKAPIESQLTDWVKSNSTPQPFIMQDEAELKTDSDEGGIVRFKQQNLTEDEVLAHIEVGKQVHKLALHFGQSIAFLMQSDAGIKRLKFSEEFRAGNDEVGTEDPMARLDADFALMGSELIALMNSLVEVLGGVEDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQX2</accession>
    <name>B1KQX2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326063.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3461"/>
    <dbReference type="EnsemblBacteria" id="ACA87728">
        <property type="protein sequence ID" value="ACA87728"/>
        <property type="gene ID" value="Swoo_3461"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3461"/>
    <dbReference type="eggNOG" id="COG2913">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160719_0_0_6"/>
    <dbReference type="OMA" id="MDWEDRQ"/>
    <dbReference type="OrthoDB" id="1711920at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037873">
        <property type="entry name" value="BamE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021534">
        <property type="entry name" value="DUF3192"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11399">
        <property type="entry name" value="DUF3192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14378" checksum="B39B6300AA9FD612" modified="2008-04-29" version="1" precursor="true">MKSKLPVIVGSIFAAYLAFVAVVVLVYDPTPDEMDWEDRQEYINAKLTEISLGQSITQIKSLLGKADFSEAKVTNENAIQVLFYRTHHKKSDGETTKDECTPLLFKDQKLIAWGEGTYQQYLTGGLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR00</accession>
    <name>B1KR00_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4274 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326090.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3491"/>
    <dbReference type="EnsemblBacteria" id="ACA87756">
        <property type="protein sequence ID" value="ACA87756"/>
        <property type="gene ID" value="Swoo_3491"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3491"/>
    <dbReference type="eggNOG" id="ENOG5033BBB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1757581_0_0_6"/>
    <dbReference type="OMA" id="WLEMNEL"/>
    <dbReference type="OrthoDB" id="2056964at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025369">
        <property type="entry name" value="DUF4274"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14096">
        <property type="entry name" value="DUF4274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4274" evidence="1">
        <location>
            <begin position="30"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="17352" checksum="6FC04AA5F61EF263" modified="2008-04-29" version="1">MNQYKFIEMICYELEDHDEAISLVKTLDSSALLYELLDHYNWDDGFGVPIAVANHPCCEVAIAQKLYWLAAADYWYESEEEVNIYNKEHFNFSKLISQRLLAGYYEVGSLSHAEYFSQVQLYKFKKQGFPDVFYQPVVGTKSKQHRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR14</accession>
    <name>B1KR14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323179.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84831">
        <property type="protein sequence ID" value="ACA84831"/>
        <property type="gene ID" value="Swoo_0535"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0535"/>
    <dbReference type="eggNOG" id="ENOG5030KGB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065572_0_0_6"/>
    <dbReference type="OMA" id="HENISRR"/>
    <dbReference type="OrthoDB" id="1660863at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="36032" checksum="E0C0B514B721544E" modified="2008-04-29" version="1">MKYVLKISSHLGIDLIESSEDELNEVKDAKSNILESVTLEEKLDLALTNYKEFEMFIASISIDYKMFKGGDWQGGMQKRRELARLFSNLLSSTRLYIDHLMHHVSRIYGKESDNYKLIKEHVSQHYDESLSYRLLETIRNHVQHAGLPISFKSMSTWNVERTHMVTIVTPTLMIEELRQNKRFKKSVLVEIESLTKSPDLKPHIRNYIGRLTQINGFVRELLNSDYQRWSELVLNCIEKGERLHLKASGSIHTALYCESDNYEVLEKIELFRDFLELREYFCQHNMVLDDFESRYVSTLPIDELRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR15</accession>
    <name>B1KR15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323180.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84832">
        <property type="protein sequence ID" value="ACA84832"/>
        <property type="gene ID" value="Swoo_0536"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0536"/>
    <dbReference type="HOGENOM" id="CLU_1407904_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="22353" checksum="4883DF7BBA4EFB65" modified="2008-04-29" version="1">MDGVIKLIISFLGGGVIAGLISWARIARSERENRKTEHIKAQVNNLYGPLYFFTSQNVQLLELNRNLMSAYNDEYVDQNWALAPETQKSINEETSTTIDIANTYVKNIIANNQKIVELLQNNSEYIDPEDNDVFHKVVIDNIRDMVEKEESGKLRTPFMVYKSVGDIFFVRQEFNELVINKFLSKNNELKKYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRI5</accession>
    <name>B1KRI5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324737.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2108"/>
    <dbReference type="EnsemblBacteria" id="ACA86392">
        <property type="protein sequence ID" value="ACA86392"/>
        <property type="gene ID" value="Swoo_2108"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2108"/>
    <dbReference type="eggNOG" id="COG4798">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072291_0_0_6"/>
    <dbReference type="OMA" id="WPGGGWY"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016980">
        <property type="entry name" value="S-AdoMet-dep_MeTrfase_Alr7345"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031679">
        <property type="entry name" value="Mtase_Alr7345_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765153" evidence="1">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="276" mass="30704" checksum="EA7AFCBBA0BBDF83" modified="2008-04-29" version="1" precursor="true">MKKRALIAGILLGATSSASVFAHEQAHEVKTLDQVVKSDFRQDKNVSRDKYRHPLETLTFFDIKPSDTVIELWPGGGWYAEVLAPYLAGEGQYVAGNFDTNPADEKKRKGYRATSGKKFEAWLKKHKTQVGQATTVTFDPPTHYVLGRDGSVDTVLTFRNLHNWAMKGYLEPVFESTYKVLKPGGTFGIVEHRGKAGMDAKTGYMDEAQVIALAEKVGFTLVAKSDVNANAKDTKDYPKGVWTLPPRLALEDVDKAKYLAIGESDRMTLKFIKNVQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRP8</accession>
    <name>DEOC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="1">DERA</shortName>
            <ecNumber evidence="1">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="1">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">deoC</name>
        <name type="ordered locus">Swoo_3549</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326146.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRP8"/>
    <dbReference type="SMR" id="B1KRP8"/>
    <dbReference type="STRING" id="392500.Swoo_3549"/>
    <dbReference type="EnsemblBacteria" id="ACA87813">
        <property type="protein sequence ID" value="ACA87813"/>
        <property type="gene ID" value="Swoo_3549"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3549"/>
    <dbReference type="eggNOG" id="COG0274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053595_3_1_6"/>
    <dbReference type="OMA" id="MNACIPP"/>
    <dbReference type="OrthoDB" id="1227369at2"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00592">
        <property type="entry name" value="DeoC_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023649">
        <property type="entry name" value="DeoC_typeII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0704">Schiff base</keyword>
    <feature type="chain" id="PRO_1000129814" description="Deoxyribose-phosphate aldolase">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="1">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00592"/>
        </source>
    </evidence>
    <sequence length="257" mass="27357" checksum="C0B7DF2126837F9E" modified="2008-04-29" version="1">MSDLKKAAQKAIELMDLTTLNDDDTDQKVIELCHKAKTPAGNTAAICIYPRFIPIARKTLNELGCEDIKIATVTNFPHGNDDIAIAVLETRAAVAYGADEVDVVFPYRSLMEGNETLGFELVKACKEACGDDAILKVIIESGVLEDPALIRKASELCIDAGADFIKTSTGKVPVNATIEAAEIMMTVISEKNTKVGFKPAGGVRDAAAAGEFLGLAARLLGDDWATPATFRFGASSLLVNLLHTLELGEEAKGPQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD95</accession>
    <name>B1KD95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3668</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326263.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3668"/>
    <dbReference type="EnsemblBacteria" id="ACA87930">
        <property type="protein sequence ID" value="ACA87930"/>
        <property type="gene ID" value="Swoo_3668"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3668"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_8_2_6"/>
    <dbReference type="OMA" id="ESLMNTW"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="281" mass="32078" checksum="C24C4F34080A8BD4" modified="2008-04-29" version="1">MDVKVFKTFLEVAKTRHFGRAAENLYITQAAVSARIKQLESFFDQVLFIRDRNSIKLTTSGERLIAYAEVMVTTLAQAKNELSLADNRSLQLTMAGTPNIWDAYLQECLIEVTEVFSGYAFQAEALSREQLNRQLLERTLDMAFAFEPLKCDELVSQKVTDIKLELVSTSQCSVDEALSQRYIYVDWGTRFSSEHAERHSQMPAPYLRTSTGRIALEFILQKGGAAYLPTSISAPYLQDNRLNLVRGAEPWDRPVYLSYRRDTLQLDAIEKIERLVKKSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD97</accession>
    <name>B1KD97_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326265.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3670"/>
    <dbReference type="EnsemblBacteria" id="ACA87932">
        <property type="protein sequence ID" value="ACA87932"/>
        <property type="gene ID" value="Swoo_3670"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3670"/>
    <dbReference type="eggNOG" id="COG3930">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026435_0_0_6"/>
    <dbReference type="OrthoDB" id="504489at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012656">
        <property type="entry name" value="CHP02421_QEGLA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012548">
        <property type="entry name" value="DUF1704"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007709">
        <property type="entry name" value="N-FG_amidohydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31817">
        <property type="entry name" value="PTHR31817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08014">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05013">
        <property type="entry name" value="FGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01154">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02421">
        <property type="entry name" value="QEGLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="672" mass="75627" checksum="FAC1F042E2120F6E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA3</accession>
    <name>B1KDA3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transglut_core2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0162 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326271.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3676"/>
    <dbReference type="EnsemblBacteria" id="ACA87938">
        <property type="protein sequence ID" value="ACA87938"/>
        <property type="gene ID" value="Swoo_3676"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3676"/>
    <dbReference type="eggNOG" id="COG2912">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063810_0_1_6"/>
    <dbReference type="OMA" id="ENKFGHA"/>
    <dbReference type="OrthoDB" id="1023028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transglut_core2" evidence="2">
        <location>
            <begin position="50"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="29517" checksum="D8C41BB15B92888D" modified="2008-04-29" version="1">MTTLPLKNEIALPEMAFEIGAHLNFSKAESANWAWLELAGSVLSHYVVDRHERLAGLLRWFYQDLGFCIRQPYFSVEAADLGTCISSRQGNSTTLATVLMLLAKQLDLKLEPLLLPGTTVLSSRIDGVVKYIDPMNGSELTRHQLHVLVRGELGNGVPFKASYLKPVSLKRLVSRMIHELKAGCIVSHKFEPALECCNLLLQWHPDDLNLNRERAFIAQQLGCINVAAADLKHFVDNSPHDPVIELVKMQLKELREEQEIYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDY0</accession>
    <name>B1KDY0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3722</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326314.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3722"/>
    <dbReference type="EnsemblBacteria" id="ACA87982">
        <property type="protein sequence ID" value="ACA87982"/>
        <property type="gene ID" value="Swoo_3722"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3722"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_4_0_6"/>
    <dbReference type="OMA" id="AHPSPGW"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="36190" checksum="F37807605F01F054" modified="2008-04-29" version="1">MTLEINLKSEITATQTGQRLDQTLAELYPDYSRTRIKEWIQAGWVYIDGVVSTKPREKVLEGQEIAIEATLKEETAAKAQAIDLDIVYEDDHIIVINKQAGLVVHPGAGNQDGTLMNALLHHCPGIELVPRAGIVHRLDKDTTGLMVVAKTVEAQTHLVSALQAREITREYEAVVLGTLISGGTVDEPIDRHPTKRTHMAVVHNGKPAMTHYRVAEKFRAHTRLRLRLESGRTHQIRVHMSHIGHTLVGDPVYGGRPRPPKGVTPEFFETYMGFKRQALHAIRLELAHPYTFEIMSWQAPVPEDMVTLTRALRKDTEENPVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE00</accession>
    <name>B1KE00_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326334.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3743"/>
    <dbReference type="EnsemblBacteria" id="ACA88002">
        <property type="protein sequence ID" value="ACA88002"/>
        <property type="gene ID" value="Swoo_3743"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3743"/>
    <dbReference type="eggNOG" id="COG3347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024866_0_0_6"/>
    <dbReference type="OMA" id="DHTHATA"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="571" mass="63037" checksum="0F1A24BF70187EB3" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA5</accession>
    <name>B1KEA5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0796</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323438.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0796"/>
    <dbReference type="EnsemblBacteria" id="ACA85091">
        <property type="protein sequence ID" value="ACA85091"/>
        <property type="gene ID" value="Swoo_0796"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0796"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088255_3_0_6"/>
    <dbReference type="OMA" id="QFVEGKH"/>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001488">
        <property type="entry name" value="Tdi_protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766493" description="Thiol:disulfide interchange protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="10"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="5">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001488-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="223" mass="25056" checksum="3F79376ADAD99FC3" modified="2008-04-29" version="1" precursor="true">MIKHIALALTLAIAPLSSFASQFVEGKHFTQVSNKAASTQPKLTEFYSFYCHNCYNMETQYLGDIKANLNKKVKFDSKHVDFMNSEIGTEVMRSLGVIQALDASQKDKLTLAMFAAIQGEEEAGSHDHAHDHSAHDKPELNNRDDIKKVFAAHGIDGKKYDELADSKVVDSKLALWRVQQREFRVQSVPAFIVNDKYAINMGEIRSLGQLIDLINYLALDHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEH0</accession>
    <name>B1KEH0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324891.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2267"/>
    <dbReference type="EnsemblBacteria" id="ACA86548">
        <property type="protein sequence ID" value="ACA86548"/>
        <property type="gene ID" value="Swoo_2267"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2267"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_2_6"/>
    <dbReference type="OMA" id="WRMGWII"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="36"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="403" mass="45319" checksum="2ECB7783497FB267" modified="2008-04-29" version="1">MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKAIVQHYQSQGIFGVDIEDVYIGNGVSELIVMAMQGLLNTDDEVLIPSPDYPLWTAAVNLSGGKAQHYRCDEEADWFPDLDDIRAKITPRTRALVLINPNNPTGAVYSRELLLEAIEICREHHLILFADEIYDKILYDEAQHVPAASLSDDILTVTFNGLSKSYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLASMRLCANVPNQHAIQTALGGYQSINELVINEGRLKVQRDTCVELLNSIPGISVKCPKGAMYAFPKLDKRFNIRDDERLVLDLLKEKKILLVHGTAFNWPEPDHLRVVFLPHKEDLEKALTEFGDFMDGYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEH9</accession>
    <name>B1KEH9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ordered locus">Swoo_2276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324900.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2276"/>
    <dbReference type="EnsemblBacteria" id="ACA86557">
        <property type="protein sequence ID" value="ACA86557"/>
        <property type="gene ID" value="Swoo_2276"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2276"/>
    <dbReference type="eggNOG" id="COG0225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_2_6"/>
    <dbReference type="OMA" id="AGPFYYA"/>
    <dbReference type="OrthoDB" id="1554384at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="4"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="159" mass="17874" checksum="9295A281FAF473B5" modified="2008-04-29" version="1">MAVATFGAGCFWGVEHFFKQVPGVLKATCGYMGGKDSTNCYEEVKTGETGHAEVVQVEFDELQVTFEDILDVFWKNHNPTSLNRQGGDIGSQYRSTIFFHDKAQKAAAELSKLSLARSGKWGARHIVTEIVPLLTFHRAEEYHQNYLEKNELPSCHIAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEM5</accession>
    <name>B1KEM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium:dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326371.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3781"/>
    <dbReference type="EnsemblBacteria" id="ACA88040">
        <property type="protein sequence ID" value="ACA88040"/>
        <property type="gene ID" value="Swoo_3781"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3781"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_1_6"/>
    <dbReference type="OMA" id="AVDWFMG"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="421" mass="44145" checksum="3C9BD11F1D57F3E3" modified="2008-04-29" version="1" precursor="true">MIKSLSTRIFIGLFSGLIFGSIIQYLLGDIGFFSGTIVEISSGVGTMFVNMIMMLVVPLVFVSIVCGVLELKDLKSFGRLGGKTFGFYIINTLVAIFAALAVALLLEPGRGVDMSGGTGAVITATELPNLVQLIVNIVPNNPVSAFTSGNMLQVIFMALLVGGVIKSLGGAVPLLVQGFQEGNKLMMKLITVVMQLAPFGVFALMLKLGATLEAEIFVSVLEYLFVILGLLLAWIFIVYPIAVGAFTSVSAKEFRAKTREQILFSLSTASSNATIPVTMRTLTDKLGVKRAVAGFGVPLGATMNMGGVSIYITIAIFFVANAFGAPIAMEQLPALLFSIFLLSVGAGGVPGGGMVMIGVLIHQMGLPVEAFAIVAALDRLIDMVLTSCNVVGDTAVLTIVDSTEKEHDEAAAEGARVSAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES7</accession>
    <name>B1KES7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326422.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3833"/>
    <dbReference type="EnsemblBacteria" id="ACA88092">
        <property type="protein sequence ID" value="ACA88092"/>
        <property type="gene ID" value="Swoo_3833"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3833"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_3_6"/>
    <dbReference type="OMA" id="ANYDAHD"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="31587" checksum="384BAC360CAF5098" modified="2008-04-29" version="1">MLRIGVDLGGTKIEAVCLDELGNELFKKRIATPREYELTLDAIVSLVEEVEVQLGKRATVGVGIPGIISPKTGLVKNANATWINGHQLDKDLGARLGREVKVANDANCFAVSEAVDGAGEGKALVFGVIIGTGCGGGLAVVGRVHEGGNGLSGEWGHNPLPWMMADEHRSTQCFCGQHDCIETFISGTGFIRDYQQGGGEPVSSGCQIMALVKAGDSVATQAFERYMDRLARALAHIINAVDPDIIVLGGGMSNVDAIYPRLPRLLSQYVLGGECMTPVVKNRFGGSSGVRGAAWLWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV2</accession>
    <name>B1KEV2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0808</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323450.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0808"/>
    <dbReference type="EnsemblBacteria" id="ACA85103">
        <property type="protein sequence ID" value="ACA85103"/>
        <property type="gene ID" value="Swoo_0808"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0808"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="MMWFTYL"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="211"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="269"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="541" mass="58716" checksum="968ABC5117DE4A5D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX4</accession>
    <name>B1KEX4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323472.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0830"/>
    <dbReference type="EnsemblBacteria" id="ACA85125">
        <property type="protein sequence ID" value="ACA85125"/>
        <property type="gene ID" value="Swoo_0830"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0830"/>
    <dbReference type="eggNOG" id="ENOG5032X2P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153653_0_0_6"/>
    <dbReference type="OMA" id="HSEWKSL"/>
    <dbReference type="OrthoDB" id="1848953at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020240">
        <property type="entry name" value="UPF0412_YaaI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10807">
        <property type="entry name" value="DUF2541"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767294" evidence="1">
        <location>
            <begin position="26"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14162" checksum="136DB4E78B8E8918" modified="2008-04-29" version="1" precursor="true">MNIKQLVAKLLVTTSLLVTACLAQADDQITLGRTILLGAGDHGAKIPLLICRKADALKVRAERNLNLEKIIVTFNNGSTKTISFYRDLKKDQETQWRGFGYKRCVKKLEVFGNSDGSRAGVKVLGRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF53</accession>
    <name>B1KF53_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrF</name>
        <name evidence="10" type="ordered locus">Swoo_2315</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the OMP decarboxylase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324936.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2315"/>
    <dbReference type="EnsemblBacteria" id="ACA86594">
        <property type="protein sequence ID" value="ACA86594"/>
        <property type="gene ID" value="Swoo_2315"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2315"/>
    <dbReference type="eggNOG" id="COG0284">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067069_0_0_6"/>
    <dbReference type="OMA" id="NFKIFLD"/>
    <dbReference type="OrthoDB" id="1150446at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01200_B">
        <property type="entry name" value="OMPdecase_type1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="PTHR32119:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="9">
        <location>
            <begin position="5"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="233" mass="24871" checksum="18A519F5C4EF711D" modified="2008-04-29" version="1">MSNKPILVALDFDDKNAALQLVDKLDPNMCRLKVGKEMFTLFGPQLVKDIHSRGFDLFLDLKFHDIPNTVAKAVSSAAELGVWMTNIHASGGLAMMEAAKKALVPYGDDAPLLIAVTVLTSMSDEDLKLIGIDVPAFEHVQRLAKLTQKAGLDGVVCSAHEAEILKASLGDSFKLVTPGIRPVGADKGDQHRIMTPPQAIAAGSDYLVIGRPITKAADPLAALTAIHQSIQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF63</accession>
    <name>B1KF63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2325"/>
    <dbReference type="EnsemblBacteria" id="ACA86604">
        <property type="protein sequence ID" value="ACA86604"/>
        <property type="gene ID" value="Swoo_2325"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2325"/>
    <dbReference type="eggNOG" id="ENOG5031GYY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2976782_0_0_6"/>
    <dbReference type="OMA" id="AWAIFHF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="56" mass="6427" checksum="7C63638B2DACDC44" modified="2008-04-29" version="1">MNLKILMTLAITLLAAWGIFHFKAELGLFILPLFIGLVSFVTLRLYRLMEKDNSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL3</accession>
    <name>B1KFL3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin_Reduct domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3930"/>
    <dbReference type="EnsemblBacteria" id="ACA88188">
        <property type="protein sequence ID" value="ACA88188"/>
        <property type="gene ID" value="Swoo_3930"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3930"/>
    <dbReference type="eggNOG" id="COG1853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113721_0_0_6"/>
    <dbReference type="OMA" id="KAHQTSA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="39"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="24267" checksum="0C51F99EC1ABBBAD" modified="2008-04-29" version="1">MMKHLTTIDIAQMQQRNRARLINSLSGFKSANLVGSQDAHGCSNLSMVSSVFHLGANPALMGMIIRPDGVPRDTLSNIKQTKSYTINHVTSEIYRKAHQTSARYDANVSEFTEVGLTEEYVEGIIAPFVMESKLKFSLEVREMTQLMINNTTLVIGEIKHVIVDALGIKSDGYIDIEALDTITVSGLDSYHQTKRLTRLSYAKPNKHLEKLPLSGGEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFP9</accession>
    <name>B1KFP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323562.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0922"/>
    <dbReference type="EnsemblBacteria" id="ACA85215">
        <property type="protein sequence ID" value="ACA85215"/>
        <property type="gene ID" value="Swoo_0922"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0922"/>
    <dbReference type="eggNOG" id="ENOG5032RRJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155271_0_0_6"/>
    <dbReference type="OMA" id="RFWVQRL"/>
    <dbReference type="OrthoDB" id="1950323at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15358" checksum="6E484B5053D5A674" modified="2008-04-29" version="1">MAKSKLSEKQFWLQRLSKTSLRALHILGVTGAGGGILLGVPQEKWIYYWCIAMTTGLLMMIWEVVRDWRWLIQLKGVLTLVKLGLLLLFIPLAQYKPELVVTTLLLSVVVSHGPAGLRHFSVIHGRRIDGRKEVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV7</accession>
    <name>B1KFV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rh family protein/ammonium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0980"/>
    <dbReference type="EnsemblBacteria" id="ACA85273">
        <property type="protein sequence ID" value="ACA85273"/>
        <property type="gene ID" value="Swoo_0980"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0980"/>
    <dbReference type="eggNOG" id="COG0004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_1_6"/>
    <dbReference type="OMA" id="IFFMHAG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019879">
        <property type="entry name" value="Ammonium_transptr_marine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03644">
        <property type="entry name" value="marine_trans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="24"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="417" mass="43971" checksum="CC4761A6CA15DDED" modified="2008-04-29" version="1">MMDELAKLGVTVSELRFALDTFYFLISGALVMWMAAGFAMLEAGLVRSKNTTEILTKNVCLYSISCVMFLIVGYNIMYVDNAAGGWLPSISTLIGSQEEGADHALESDFFFQVVFVATAMSIVSGAVAERMKLWAFLAFSVVMTGFIYPVEGYWTWGEGFLYKAGFVDFAGSGIVHMAGAAAAIAGVLLLGARKGKYGPNGQVNPIPGSNLPMATLGMFILWMGWFGFNGGSQLLVSDAENATAVAKIFLNTNSAAAFGAVSALVVCRMVWGKADLTMILNGALAGLVAITADPLSPSIAFAGVIGLVAGGVVIFSIVALDRLRIDDPVGAISVHGVAGFLGLMLVPLSNADATVLGQLYGAGVIFAWVFSASLAVWYALKLSMGIRVSEEEEYKGMDASDCGIDAYPEFVSIKSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFX7</accession>
    <name>B1KFX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325026.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2406"/>
    <dbReference type="EnsemblBacteria" id="ACA86684">
        <property type="protein sequence ID" value="ACA86684"/>
        <property type="gene ID" value="Swoo_2406"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2406"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045103_1_0_6"/>
    <dbReference type="OMA" id="EDYGDEW"/>
    <dbReference type="OrthoDB" id="923283at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="65"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="39941" checksum="0E9E1474C3DAD746" modified="2008-04-29" version="1">MNFKGVDYVNKEINLFEFLATIPKNTGRKAMPALKCKDGGWLCDTPLIMEELEKRHPQPSIEIHTSIQRFVAELFQNWMDDVGIPIALHSRWSYPENYEKLNREEAGKNLLPFMPKFIRNKVADKALSDAMSEKLPNMGVTPDQIPLLEKWATHILGLLDVHLSQYDYLLGGRPTVADYALLGLMQGHLNRDPWPKREWIDLRPHLQKWVEKTHSGAPAKGDLLADDQIPDTLMPIVRIIFDEYMPLMDLTVKQIRLLINEEGLLPGDELPRSTERFLFKMGDGQFKRASFTYSVWRMQRLQKIVSAFSKEEQNRLAAWLLEQGQYNFLDLDFGPNLKPQGLTAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY3</accession>
    <name>B1KFY3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative gluconeogenesis factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for morphogenesis under gluconeogenic growth conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gluconeogenesis factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325032.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2412"/>
    <dbReference type="EnsemblBacteria" id="ACA86690">
        <property type="protein sequence ID" value="ACA86690"/>
        <property type="gene ID" value="Swoo_2412"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2412"/>
    <dbReference type="eggNOG" id="COG0391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044041_2_0_6"/>
    <dbReference type="OMA" id="LCGDDDW"/>
    <dbReference type="OrthoDB" id="665169at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00973">
        <property type="entry name" value="Gluconeogen_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010119">
        <property type="entry name" value="Gluconeogen_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30135">
        <property type="entry name" value="PTHR30135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01826">
        <property type="entry name" value="CofD_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="300" mass="32370" checksum="6B7CEB4846102872" modified="2008-04-29" version="1">MQYNALNRFDKVVAIGGGHGLGRVLSTLSFLGPKLTGIVATTDNGGSTGRLRQQQDCIAWGDLRNCLSQLASTPSIGSLLFEYRFAGESDLSGHNLGNLMLLALDELCVRPLEAVNIVRQFLNIETRVIPMSEEPTHLVAIQACGNKIFGETSVDEMSEHPMALSLEPAVAATCEACDAVREADLVILGPGSFLTSIMPPLLLPKFAAALAESNAEVILIDNLTREPSSSADFSLTQRVDWCHQVLGVKIIDRILSHSEVSYQSGNILYRPLVSKHHKGLHDRKALAQALASIVSDTITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG39</accession>
    <name>B1KG39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325088.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2469"/>
    <dbReference type="EnsemblBacteria" id="ACA86746">
        <property type="protein sequence ID" value="ACA86746"/>
        <property type="gene ID" value="Swoo_2469"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2469"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="NRTINVW"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="892"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="917"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="943"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="989"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1020"/>
            <end position="1046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1073" mass="119176" checksum="4C686E00E444D678" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGA2</accession>
    <name>B1KGA2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3982</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326569.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3982"/>
    <dbReference type="EnsemblBacteria" id="ACA88239">
        <property type="protein sequence ID" value="ACA88239"/>
        <property type="gene ID" value="Swoo_3982"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3982"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_3_6"/>
    <dbReference type="OMA" id="AAPMTWM"/>
    <dbReference type="OrthoDB" id="1992113at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="17"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="115"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="172" mass="20082" checksum="2A98FBF4912DF8B5" modified="2008-04-29" version="1">MLLARTAMGDREAFKSLYLSLSPKIFPVLMQLMHDRQLAEDLLQDTFVRIWEQASRYDLNKSGAYTWSYTIARHLALDHLRRSSKRRTEHHTEREIELDVTESNMFSSSSHTQGRVDNCLSQLKGDQRQAVILSYCYGYEQRELVGVLSHPLGTIKSWLRRGMEFMQQCVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGA6</accession>
    <name>B1KGA6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Copper resistance lipoprotein NlpE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326573.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88243">
        <property type="protein sequence ID" value="ACA88243"/>
        <property type="gene ID" value="Swoo_3986"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3986"/>
    <dbReference type="eggNOG" id="COG3015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095662_0_0_6"/>
    <dbReference type="OMA" id="VIPCASC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007298">
        <property type="entry name" value="Cu-R_lipoprotein_NlpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04170">
        <property type="entry name" value="NlpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767331" evidence="1">
        <location>
            <begin position="18"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17465" checksum="639A66BA5377DBCE" modified="2008-04-29" version="1" precursor="true">MKLQLITLPLLALTVLACSDLTDSKSAPQPIKESVKSEEIAPPIAVGDNSQNSLDWNGRYSGITPCASCEGIKTELILYYDNTYKLVTIYLGKSSKRFIETGKLKWNEAGAAITLHANGSDQSGNQYQVGENQLFMLDREGQRITGELAEYYRLAKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC5</accession>
    <name>B1KGC5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MotA/TolQ/ExbB proton channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4006"/>
    <dbReference type="EnsemblBacteria" id="ACA88262">
        <property type="protein sequence ID" value="ACA88262"/>
        <property type="gene ID" value="Swoo_4006"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4006"/>
    <dbReference type="eggNOG" id="COG0811">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053325_5_0_6"/>
    <dbReference type="OMA" id="GIWLQEK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="88"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="27079" checksum="331D5B72AE3A3F17" modified="2008-04-29" version="1">MPHSLYHTLSEQLGYLTWPLFICAFITLMIILERLALMLFELPKRDTWLTKLREGTSSATSEQCQQLLTQLSRGNSMLAKGSYLLLTHRDQSREMREEIINLWLLKQRGKLQSGLKVLQVMGIITPLLGLLGTVLGLIEMFNQLGLSQGPVTPAQLASGLGLAMNTTAAGLIIAVPAITLAHLFTLWAEQRCSNIAHGLNQLNLWLDGFDQAMKIGQEAAGHQQIMTQTSLDKIQENRPESTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGF0</accession>
    <name>B1KGF0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent transcriptional regulator, MalT-like, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326616.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4031"/>
    <dbReference type="EnsemblBacteria" id="ACA88287">
        <property type="protein sequence ID" value="ACA88287"/>
        <property type="gene ID" value="Swoo_4031"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4031"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006325_3_0_6"/>
    <dbReference type="OMA" id="ICAGPGW"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="831"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="896" mass="102747" checksum="D5CE32A226EB39A9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGH9</accession>
    <name>RSMA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="1">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmA</name>
        <name evidence="1" type="synonym">ksgA</name>
        <name type="ordered locus">Swoo_1014</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323654.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KGH9"/>
    <dbReference type="SMR" id="B1KGH9"/>
    <dbReference type="STRING" id="392500.Swoo_1014"/>
    <dbReference type="EnsemblBacteria" id="ACA85307">
        <property type="protein sequence ID" value="ACA85307"/>
        <property type="gene ID" value="Swoo_1014"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1014"/>
    <dbReference type="eggNOG" id="COG0030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041220_0_1_6"/>
    <dbReference type="OMA" id="KEEEPYF"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000130322" description="Ribosomal RNA small subunit methyltransferase A">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <sequence length="267" mass="30249" checksum="E711489788A7D590" modified="2008-04-29" version="1">MSNKVHLGHTARKRFGQNFLTDHNVINRIVGAISPDNDHVMVEIGPGLAALTEPVANAIDKLTVVELDKDLVARLQEHPTLKDKLDIHQGDALQFDFSQLVEEGRQMKVFGNLPYNISTPLMFHLFEFAEQIENMHFMLQKEVVLRLSASPGTKAYGRLTVMAQYHCQVMPVLEVPPGSFTPPPKVDSAVVRLVPYKVKPWPCKDVDQLRHLTTTAFNMRRKTLRNNLKHMISDEEFAELGIDATLRPEQITVEQYVAMANFVVDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT9</accession>
    <name>B1KGT9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325149.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2531"/>
    <dbReference type="EnsemblBacteria" id="ACA86808">
        <property type="protein sequence ID" value="ACA86808"/>
        <property type="gene ID" value="Swoo_2531"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2531"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_5_6"/>
    <dbReference type="OMA" id="YAVWYEY"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="209"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="38839" checksum="A2A53EDDF42099F4" modified="2008-04-29" version="1">MNLAKHLSDIEVSAKILRHAVPKMSELDIPVTPDNYSVWYEYFLGVNLDLNRTIDEYISKGVTFTAEINSELVKNYILEQSPEVIENVHVETQLVINNLLEKVTQMSSGTANLTETLSEFHQELKQTVDADVLLKLVNTLADEMGSVISDNKQMEASLNTMNEEVSSLKSEMENLSIVAQTDQLTSLFNRRAFEKEIESHMIHYKQDHSASCLLVVDIDHFKLFNDTHGHLIGDKVLAYVALALKKTVKGTDFVARYGGEEFVVLLPNTELNDALTVAELVRQKIANQKLSIGKEDKHSLGSITVSVGVSTLHNSDDRESYFIRADEALYRAKSSGRNCICSELAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU1</accession>
    <name>B1KGU1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325151.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2533"/>
    <dbReference type="EnsemblBacteria" id="ACA86810">
        <property type="protein sequence ID" value="ACA86810"/>
        <property type="gene ID" value="Swoo_2533"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2533"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_11_1_6"/>
    <dbReference type="OMA" id="VMWIEEA"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15979" checksum="5D415E384190C4D4" modified="2008-04-29" version="1">MKSTEDKLNHAMVEFYEKLSSWEQAVVKGKEVSLPQVHTVEILGGNGPMRMKELADKIGVTTGTLTVQIDKMVKSGLVIRKPNELDKRSILVELTEKGREMFEEHDELHHQLTSELTVKFTQEERELLLNFLERVNAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH07</accession>
    <name>B1KH07_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2063 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326648.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4063"/>
    <dbReference type="EnsemblBacteria" id="ACA88319">
        <property type="protein sequence ID" value="ACA88319"/>
        <property type="gene ID" value="Swoo_4063"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4063"/>
    <dbReference type="eggNOG" id="COG3219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086594_1_0_6"/>
    <dbReference type="OMA" id="QCELMLN"/>
    <dbReference type="OrthoDB" id="1675974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018640">
        <property type="entry name" value="DUF2063"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09836">
        <property type="entry name" value="DUF2063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2063" evidence="1">
        <location>
            <begin position="6"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="30896" checksum="5A334505987E687B" modified="2008-04-29" version="1">MTSLKQTQALFMTYILSDKESDADQDDKFSAFSSIITAKSEEDGKTRLGIYASAYRLRLIETIETDHEILGVYLGDELFDKMAQAYINAHPSSFRSLRHFCDALPQFLSDDSFFSQYPILSHIATFERRLLNAFDAEEQPRASFTELEQLAPEHWPESQFRFHSSVQIFQCQSNAVESWQALKNEQTPPQPDYSIASAWLLWRGEERLTEFISLTEYQLVLLEGFIKGNTLAQQCELMLNYFDEEQAPVKVLQAIRAWFDMGIIRAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH11</accession>
    <name>B1KH11_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326652.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4067"/>
    <dbReference type="EnsemblBacteria" id="ACA88323">
        <property type="protein sequence ID" value="ACA88323"/>
        <property type="gene ID" value="Swoo_4067"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4067"/>
    <dbReference type="HOGENOM" id="CLU_1395465_0_0_6"/>
    <dbReference type="OrthoDB" id="2157898at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="195" mass="21720" checksum="560729B718564013" modified="2008-04-29" version="1" precursor="true">MSLYLGFTFFSLFIGFLLGASNTPVIGLFLTSIFGFIGTLLGTQYVLNINNSNKYGAKFLGISMLVVSISLFIGTVSGGFYRTESNIQVNQILPWEGAAKPKSTKEALDWILVKEKMNLLGYSDEDVAKIYQIRSEEIELLAEIIKQESTQEEDLYSSELPTVIYDESAPFYLVFPKEITPKKRANRAPSSINGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH13</accession>
    <name>B1KH13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Two component, sigma54 specific, transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4069</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326654.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4069"/>
    <dbReference type="EnsemblBacteria" id="ACA88325">
        <property type="protein sequence ID" value="ACA88325"/>
        <property type="gene ID" value="Swoo_4069"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4069"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_6_6"/>
    <dbReference type="OMA" id="YYRLHIV"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="8">
        <location>
            <begin position="153"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="417"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="417"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="485" mass="52678" checksum="1AEBD36E96E7B6BB" modified="2008-04-29" version="1">MDTILIVDDNQAVCNALSLMLELNGFNTLTCLSPEVALELIRLHDIALVVQDMNFTQDTTSGEEGKALFYALRELQPELPIVLLTAWTQLEIAVELVKEGAADYMGKPWDDTKLVTSINNLISLHALSKANTQLTRVENDRMSAIKGADLCGIVFGSGAMQRSVDLALQIARSDVSVLITGPNGAGKDKLADIIHANSSLKTKPFIKVNVGALPIDLLEAELFGAEAGAFTGANKTRIGRFEAADGGTLFLDEIGNLPLSGQIKLLRVLQTGEFERLGSHQTKKVNVRVLSATNADLAEDIKQGCFREDLFYRLNVIELALAPLNQRQDDILPLVEHFIGREFSLNKQAQESLVAHPWPGNVRELENACKRAVILASSPKLTPSDFGLGSISHLSEDDSSVRSAQVQALVQSQVQAQSDTASSISPESTEQLDSRGAETDKTQLEKSEIEAALIQHGGVIARVAKSLGLSRQALYRRMEKFGIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH61</accession>
    <name>B1KH61_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4117</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326702.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4117"/>
    <dbReference type="EnsemblBacteria" id="ACA88373">
        <property type="protein sequence ID" value="ACA88373"/>
        <property type="gene ID" value="Swoo_4117"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4117"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047522_1_1_6"/>
    <dbReference type="OMA" id="IYVRTCR"/>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="260"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="341" mass="38627" checksum="D5A6AA1F5E7C97D7" modified="2008-04-29" version="1">MTLEDKLTVPTEATTLSSWALAICRTIDSYGVESGELLQQVGINPTLLQDPNARIPTKLVTQLWQLAVVTTGDESIGLKVANFVQPTSFNALSFSLLVSESLLDAWERVKRYYEIISNVLEMKIERGEKESALCFIRLPEKHYADEAIDAFMATNLSISRQISHGQLQPSKLELERATPINLSPFHSLFLCPIEFNSDGNRIYFTNEALNIPFPSANRALALKNDLAVEEYLAQLSAQSFSSKVAKEIVIAMSLGNPERESIAKTFHMSSRNLQRKLKHEQTSFSELLDSIRKDLALKYILNSEVAIIEISFRLGFKDPSNFTRAFKRWYQKSPLQYRKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF5</accession>
    <name>B1KHF5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323809.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85463">
        <property type="protein sequence ID" value="ACA85463"/>
        <property type="gene ID" value="Swoo_1170"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1170"/>
    <dbReference type="eggNOG" id="ENOG5031H7H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_200565_0_0_6"/>
    <dbReference type="OMA" id="ICTKELL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="67" mass="7577" checksum="DFCF082BF18D06E6" modified="2008-04-29" version="1" precursor="true">MKFLLRAVLLLGSLVWLVICAKQFVGFGILDDLAVAIDHPTLLIQTFIALLILRSAWMSGHEKRRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH1</accession>
    <name>B1KHH1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zn_protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325196.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2579"/>
    <dbReference type="EnsemblBacteria" id="ACA86856">
        <property type="protein sequence ID" value="ACA86856"/>
        <property type="gene ID" value="Swoo_2579"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2579"/>
    <dbReference type="eggNOG" id="COG4067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070079_0_0_6"/>
    <dbReference type="OMA" id="KGEQYHQ"/>
    <dbReference type="OrthoDB" id="1576021at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008503">
        <property type="entry name" value="Put_Zn_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05618">
        <property type="entry name" value="Zn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_protease" evidence="1">
        <location>
            <begin position="105"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="27192" checksum="3C2D56F57DB53162" modified="2008-04-29" version="1" precursor="true">MFKQIICIAIAAGLTGCAATSQENANLPKPVDVTVLDTSLARQQADLIQIMDDSNTAQSAAISGLSKQIVSLEKKLSTLKLSPEEKVVPVALDCPPSPLAGKFLLGAIENVFVEEVKASFNTRIDTGAESSSLDARNIILFERDGKQWVRFDVFTLGEDAPAQTFESKVERFVRIKQDSDEKTDRRPVIHAHLKIGQYSAETDLNLVDRSHLDFPLLLGRKFMQDIAVVDVGQTYIHGKKKPAVESAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL3</accession>
    <name>B1KHL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lytic transglycosylase catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2621</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325238.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2621"/>
    <dbReference type="CAZy" id="GH23">
        <property type="family name" value="Glycoside Hydrolase Family 23"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86898">
        <property type="protein sequence ID" value="ACA86898"/>
        <property type="gene ID" value="Swoo_2621"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2621"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019016_0_1_6"/>
    <dbReference type="OMA" id="RQESAFM"/>
    <dbReference type="OrthoDB" id="859969at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023800">
        <property type="entry name" value="Cucumovirus_coat_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037061">
        <property type="entry name" value="Lytic_TGlycoase_superhlx_L_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012289">
        <property type="entry name" value="Lytic_TGlycosylase_superhlx_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008939">
        <property type="entry name" value="Lytic_TGlycosylase_superhlx_U"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00760">
        <property type="entry name" value="Cucumo_coat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14718">
        <property type="entry name" value="SLT_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48435">
        <property type="entry name" value="SSF48435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764488" evidence="3">
        <location>
            <begin position="36"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Cucumo_coat" evidence="4">
        <location>
            <begin position="161"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="SLT_L" evidence="6">
        <location>
            <begin position="415"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="5">
        <location>
            <begin position="490"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="650" mass="74855" checksum="2E3FB6B27B529C71" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI34</accession>
    <name>B1KI34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323858.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1219"/>
    <dbReference type="EnsemblBacteria" id="ACA85512">
        <property type="protein sequence ID" value="ACA85512"/>
        <property type="gene ID" value="Swoo_1219"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1219"/>
    <dbReference type="HOGENOM" id="CLU_2002357_0_0_6"/>
    <dbReference type="OrthoDB" id="2227743at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766641" evidence="1">
        <location>
            <begin position="26"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="13772" checksum="B17FB585F89F9A3B" modified="2008-04-29" version="1" precursor="true">MNINRNSSLLLGFTLLATTTFPTLATDRNPGVICAEKQFITAIDFGYVTNIKGGPDWANAVNVHLANGVEIPLNYKYNANDDGGKSIIAALRMAFSFNREVTLWDHDHNNCDDFDQVRVHPALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KID2</accession>
    <name>B1KID2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylosuccinate lyase</fullName>
            <shortName evidence="11">ASL</shortName>
            <ecNumber evidence="4 11">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2707</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325320.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2707"/>
    <dbReference type="EnsemblBacteria" id="ACA86983">
        <property type="protein sequence ID" value="ACA86983"/>
        <property type="gene ID" value="Swoo_2707"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2707"/>
    <dbReference type="eggNOG" id="COG0015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025566_2_0_6"/>
    <dbReference type="OMA" id="TQVNPCD"/>
    <dbReference type="OrthoDB" id="347727at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="12">
        <location>
            <begin position="14"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="13">
        <location>
            <begin position="331"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="456" mass="51152" checksum="B407BC9F89A69172" modified="2008-04-29" version="1">MELSALTAISPVDGRYGSKTASLRGIFSEYGLTKYRVQVEINWLKLLSSCPEIEEVPPFSETALALLDSIKDNFNEADALRIKTIEATTNHDVKAVEYFIKEQIADNAELVAIDEFVHFACTSEDINNLSHGLMLLEAREQVLVPYCQQIVDAIKGLAREHRSVPLMSRTHGQPASPSTLGKEMANVAIRLERQLKQIESVEVMGKINGAVGNYNAHLSAYPEVDWHAVSERFVTSLGLNWNPYTTQIEPHDYIAELFDAVARFNTILIDFDRDIWGYIALGHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGIANALMQHLAAKLPVSRWQRDLTDSTVLRNLGVGMAHALIAYQSTLKGISKLEVNEEQLRAELDKNWEVLAEPVQTVMRRYGIEKPYEKLKELTRGKRIDGEQLAQFIDGLALPQEVKVELKKMTPANYIGRAESFVDEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE8</accession>
    <name>B1KIE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate (FAA) hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325336.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2723"/>
    <dbReference type="EnsemblBacteria" id="ACA86999">
        <property type="protein sequence ID" value="ACA86999"/>
        <property type="gene ID" value="Swoo_2723"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2723"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_5_2_6"/>
    <dbReference type="OMA" id="TELCFIY"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="80"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="22733" checksum="D1F78EA8CCDF73C2" modified="2008-04-29" version="1">MNTVCVDGKNFSPSKIICVGRNYVEHIRELNNEVPDELLLFVKPNSAISTELTSFHQEALHYEAELSFLYENGRFSAVGLGLDLTKRALQSELKAKGLPWERAKAFDGSGLFSSFVYIEKISSELNFKLTINGNLAQSGHIKLMMNSPERILTEISSFMRLEDGDIVMTGTPKGVGEIHLGDRFELTLFDEEVELTKAAWKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIF2</accession>
    <name>B1KIF2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutaredoxin, GrxA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2727</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325340.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2727"/>
    <dbReference type="EnsemblBacteria" id="ACA87003">
        <property type="protein sequence ID" value="ACA87003"/>
        <property type="gene ID" value="Swoo_2727"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2727"/>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026126_7_3_6"/>
    <dbReference type="OMA" id="VGGCTEF"/>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011902">
        <property type="entry name" value="GRXA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02183">
        <property type="entry name" value="GRXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="9994" checksum="74F6F2461F9FA527" modified="2008-04-29" version="1">MFVVIFGRPGCPYCVRAVQLSEQLTEARSDFKFKYVDIHAEGISKADLEKTVGKPVETVPQIFVDKEHVGGCTEFEQYVRDNQLLATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII6</accession>
    <name>B1KII6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Periplasmic serine protease DegS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4226</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326809.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4226"/>
    <dbReference type="EnsemblBacteria" id="ACA88482">
        <property type="protein sequence ID" value="ACA88482"/>
        <property type="gene ID" value="Swoo_4226"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4226"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_2_2_6"/>
    <dbReference type="OMA" id="THGWVLE"/>
    <dbReference type="OrthoDB" id="741829at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011783">
        <property type="entry name" value="Pept_S1C_DegS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02038">
        <property type="entry name" value="protease_degS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="261"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611783-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="361" mass="37713" checksum="990E622690BE7029" modified="2008-04-29" version="1">MAIKDTLLYVGKAVTFGLIMAAVFLFVTPLLTDNGSSNLFFQKRGDNGFELSFSKAVRRAAPAVVNIYSLSVNRNQPLNSGSLQGLGSGVIMSKEGYILTNYHVVKKADEIVVALQDGRKFTSEVVGSDPVTDLAVLKVEGDTLPIVPINLGVPAQVGDVVLAIGNPYNLGQTITQGIISATGRNGLSSGYLDFLQTDAAINAGNSGGALIDTSGQLIGINTAAFQIGGEGGGHGINFAIPIKLAHSIMGKLIKDGRVIRGALGITGEPVGPVIAQILNLPDLTGVVITGVDPHGPAAQAQLQARDVITKFEGEAVPGVEMLMDRIAESTPNKQVTMTIIRKGKVYDVPVTIGENVVEETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIJ0</accession>
    <name>B1KIJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Toluene tolerance family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4230"/>
    <dbReference type="EnsemblBacteria" id="ACA88486">
        <property type="protein sequence ID" value="ACA88486"/>
        <property type="gene ID" value="Swoo_4230"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4230"/>
    <dbReference type="eggNOG" id="COG2854">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094502_3_0_6"/>
    <dbReference type="OMA" id="FTEYTDQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008869">
        <property type="entry name" value="MlaC/ttg2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042245">
        <property type="entry name" value="Tgt2/MlaC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36573">
        <property type="entry name" value="PTHR36573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05494">
        <property type="entry name" value="MlaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004649">
        <property type="entry name" value="MlaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764917" evidence="1">
        <location>
            <begin position="26"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="25181" checksum="61FA78E9C6244E0D" modified="2008-04-29" version="1" precursor="true">MRMFNQIFKLTASLFLLVFSATAHSQEVEVNTMDPYVMVETVANNTFDRFHHDFAIIETNPDHLKVIVSDELMPYIDTKYASYKVMGTYLRKTTKEQRERFVEAFKGYLISTYAQAFTEYTDQKVSFARAADFSKEKMVSVDVQIIDAGRPPIKLQFRVRRLKDDSWKAFDLVAEGVSLLASKSSEISNLIRQKGIDAVIAELDERTKVSIHRGSADKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM3</accession>
    <name>B1KIM3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326846.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4263"/>
    <dbReference type="EnsemblBacteria" id="ACA88519">
        <property type="protein sequence ID" value="ACA88519"/>
        <property type="gene ID" value="Swoo_4263"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4263"/>
    <dbReference type="eggNOG" id="COG3738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079833_2_0_6"/>
    <dbReference type="OMA" id="PGNLPHI"/>
    <dbReference type="OrthoDB" id="1208786at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009706">
        <property type="entry name" value="DUF1287"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06940">
        <property type="entry name" value="DUF1287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011444">
        <property type="entry name" value="DUF1287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767097" evidence="1">
        <location>
            <begin position="20"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="205" mass="22754" checksum="6DAE4DB4906B4927" modified="2008-04-29" version="1" precursor="true">MERLTLALFLLCSSAVCGAASASSLVDAALERTEHSVRYDGAYHSISYPNGDVPANIGVCTDVIIRSYRQLNVDLQALVHEDMLANFSEYPSKRIWGLTRPDSNIDHRRVPNLQTFFTRHGEVLPISQSAQSYRSGDIVTWMLPGNLPHIGIIVSQGVGDNEKPYVVHNIGSGPVLEDMLFDYQITGHYRYDVEANKVTLSSNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIT1</accession>
    <name>B1KIT1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323925.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1287"/>
    <dbReference type="EnsemblBacteria" id="ACA85579">
        <property type="protein sequence ID" value="ACA85579"/>
        <property type="gene ID" value="Swoo_1287"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1287"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_6_4_6"/>
    <dbReference type="OMA" id="TIWYSIA"/>
    <dbReference type="OrthoDB" id="1772343at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="98" mass="11356" checksum="31A1A14978434C07" modified="2008-04-29" version="1">MNIELMQQRADHAVVMLKALANERRLFILCYLLSEGEMCVGEMNKKLGLSQSALSQHLAWLRKDNLVETRKEAQTVYYSLKSQEVSEIIKLLNNIYCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU5</accession>
    <name>B1KIU5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_1301</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323939.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1301"/>
    <dbReference type="EnsemblBacteria" id="ACA85593">
        <property type="protein sequence ID" value="ACA85593"/>
        <property type="gene ID" value="Swoo_1301"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1301"/>
    <dbReference type="eggNOG" id="COG4970">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084761_4_1_6"/>
    <dbReference type="OMA" id="CAYESES"/>
    <dbReference type="OrthoDB" id="1621805at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="12">
        <location>
            <begin position="44"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="177" mass="18984" checksum="8F6EFA8796AADC9F" modified="2008-04-29" version="1">MLTLEKGFTLVELMVTLVIGMILITVGVPSFTEMYQGYRAESEIRKVQQYLMFARSQAVSYGARVTVCPISGTSCGSDWKSGFSIFIDNGAAATIDSTNGVTDPIIKQVDAFNSKDFFTYAGSSVSFTPDGLIPTNSTVGTFSYCPGSTTSENSRGVEVSSSGKVRFSDSIINCTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ08</accession>
    <name>B1KJ08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS200-family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325364.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87028">
        <property type="protein sequence ID" value="ACA87028"/>
        <property type="gene ID" value="Swoo_2752"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2752"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101320_0_1_6"/>
    <dbReference type="OMA" id="ISLCKYH"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="11"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="144" mass="17346" checksum="339508DDD96B72A6" modified="2008-04-29" version="1">MSRYEKASHVYWRCQYHIVWTPKYRFRILKNKLGKDVYRCIHVYSEQLGCVVVELNVQIDHVHLVIKVPPKLSISKLMGALKGKIALKMFSKYPYLRKNKLWGNHFWQRGYFVDTVGINEEVIRRYVKHQEKVEKQEQPQLDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ34</accession>
    <name>B1KJ34_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1722 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2778"/>
    <dbReference type="EnsemblBacteria" id="ACA87054">
        <property type="protein sequence ID" value="ACA87054"/>
        <property type="gene ID" value="Swoo_2778"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2778"/>
    <dbReference type="eggNOG" id="COG1683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076318_0_0_6"/>
    <dbReference type="OMA" id="CGLERVK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007553">
        <property type="entry name" value="2-thiour_desulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013560">
        <property type="entry name" value="DUF1722"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017087">
        <property type="entry name" value="UCP037004"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04463">
        <property type="entry name" value="2-thiour_desulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08349">
        <property type="entry name" value="DUF1722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037004">
        <property type="entry name" value="UCP037004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1722" evidence="1">
        <location>
            <begin position="190"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="314" mass="35571" checksum="61EBDD7C3225569A" modified="2008-04-29" version="1">MDKKLNIGISACVMGENVRYDSGHKRSQFCTEALSEFANFKAFCPEVAIGLPIPRPTIRQIIKDNIITVSRPDGSGDVTEKLTAYGKQVGEQISHLSGFIFCAKSPSCGMERVKVHHHHGKGSESNGVGLFAREVMKANPLLPAEENGRLNDAVIRENFMTRVFTYQKWLDLAASGITKHKLIQFHSEQKYLVMSHHIESYRQLGTLLGSSDLALDELANQYIAGLMEALKNKASRKSHTNTLHHLQGYFKKQLDHAKRQELTEQIDAYRLGLTPLLVPLTLIKHYLLEFPNEYLKQQAYLNPHPKELRLRYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJE3</accession>
    <name>B1KJE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4362</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326941.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4362"/>
    <dbReference type="EnsemblBacteria" id="ACA88615">
        <property type="protein sequence ID" value="ACA88615"/>
        <property type="gene ID" value="Swoo_4362"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4362"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="QEFNVDR"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="322" mass="35503" checksum="D330A82C80278A02" modified="2008-04-29" version="1">MSSLSRSSELAIDAKGLTKKFGQLAAVSDLNLQVPKGHIYGFLGPNGCGKSTSIRMLTGLLTPTEGSIQVLGMSIPKQAEALRLRIGYMTQKFSLYEDLTVKENLEFIAQIYCLSPNDSHSKISKLISTYNLLKQQHQFAGTLSGGQKQRLSLACACLNDPELLFLDEPTSAVDPQNRRDFWEQLFDLSETGTSILVTTHYMDEAERCHGLAIMEQGFIRADGSPNDLMQQMGANVLEVSHSNLRELKNSLTTFKEIKSAAQLGSRLRVLVDNRVTDPATWLRQTMPTLHQAEIRLAPPNLEDVFVTVTGQQPSSSLTSAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJJ8</accession>
    <name>B1KJJ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ettA</name>
        <name evidence="10" type="ordered locus">Swoo_1379</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324017.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1379"/>
    <dbReference type="EnsemblBacteria" id="ACA85671">
        <property type="protein sequence ID" value="ACA85671"/>
        <property type="gene ID" value="Swoo_1379"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1379"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_6"/>
    <dbReference type="OMA" id="ISYKPQY"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="PTHR43858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="6"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="324"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Arm" evidence="7">
        <location>
            <begin position="95"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="PtIM" evidence="7">
        <location>
            <begin position="242"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="356"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="554" mass="62179" checksum="8E0F13912B16C338" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-11-03" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL0</accession>
    <name>ACDH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetaldehyde dehydrogenase</fullName>
            <ecNumber evidence="1">1.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Acetaldehyde dehydrogenase [acetylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1391</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:23288"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetaldehyde dehydrogenase family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="ACA85683" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="1.2.1.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85683.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJL0"/>
    <dbReference type="SMR" id="B1KJL0"/>
    <dbReference type="STRING" id="392500.Swoo_1391"/>
    <dbReference type="EnsemblBacteria" id="ACA85683">
        <property type="protein sequence ID" value="ACA85683"/>
        <property type="gene ID" value="Swoo_1391"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1391"/>
    <dbReference type="eggNOG" id="COG4569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062208_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008774">
        <property type="term" value="F:acetaldehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01657">
        <property type="entry name" value="Ac_ald_DH_ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003361">
        <property type="entry name" value="Acetaldehyde_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015426">
        <property type="entry name" value="Acetylaldehyde_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09290">
        <property type="entry name" value="AcetDehyd-dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015689">
        <property type="entry name" value="Actaldh_dh_actl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03215">
        <property type="entry name" value="ac_ald_DH_ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000387741" description="Acetaldehyde dehydrogenase">
        <location>
            <begin position="1"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="1">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="174"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="315" mass="33801" checksum="B05896ECA2B64FE3" modified="2009-11-03" version="2">MVNKKINIALIGSGNIGTDLMIKALRSSTLNPVWMVGIDENSDGLKRAKALGLKTTHLGIDELLTHIEADNIQIAFDATSAYVHEENNRKLQSKGVKVIDLTPAAIGPYCIPPVNLESLLSQTENQTQINDGSISGNLNMVTCGGQATIPIIAAISRVQSVDYGEIVATIASKSAGPGTRKNIDEFTRTTADAIEQIGGARQGKAIIVMNPAEPPLMMRDTVHCLTQDEPDVEAITASVLSMIEQVQEYVPGYRLKNGPVFDGNRVSVFLEVAGLGDYLPEYAGNLDIMTSAALCTGEMLARNLRSNMSVKDSHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJN2</accession>
    <name>B1KJN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324051.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1413"/>
    <dbReference type="EnsemblBacteria" id="ACA85705">
        <property type="protein sequence ID" value="ACA85705"/>
        <property type="gene ID" value="Swoo_1413"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1413"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_684937_0_0_6"/>
    <dbReference type="OMA" id="VYQIQDL"/>
    <dbReference type="OrthoDB" id="401909at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="44"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="402" mass="44954" checksum="8C21037AC0D9C479" modified="2008-04-29" version="1">MDQTTSKVKSMYEQYPYPSGDPTIRPGFDIRLLLSYVANQRTSDKPLQVLDAGCGRGPGVIGAASLQPDVMFTAIDINSVGLAEASANAKARGLTNINFVQADLMTLEGLEVPEGGFDVIYSSGVLHHLADPQIGLNNLTKILAPHGVISLMLYGSFGRQALYRLIEGIDILSPKDDPIESRIPMGRLLAKVAEETIFKDNYWKSTYRNPDVEFVDTCLNVNEVSYDITSLWQLIEQANMKFVRWVEPDVWSVEKRFDDPELLERLQALSDVEQYQIIERLFEVPKLDFIICGADNFAKPKLTEAEVDSSIFAVNPETSFSIEKRNQNQSQRIESVSYKVRHRESQNVSDPILAQLVLLLAEQTTCFSGADLVNVLAQSSVDREIAIEVIFDLLDEEVIFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR5</accession>
    <name>B1KJR5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pseudouridine-5'-phosphate glycosidase</fullName>
            <shortName evidence="6">PsiMP glycosidase</shortName>
            <ecNumber evidence="6">4.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">psuG</name>
        <name evidence="7" type="ordered locus">Swoo_1446</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>D-ribose 5-phosphate + uracil = H2O + psi-UMP</text>
            <dbReference type="Rhea" id="RHEA:18337"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:58380"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="4.2.1.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the pseudouridine-5'-phosphate glycosidase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.70" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324084.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1446"/>
    <dbReference type="EnsemblBacteria" id="ACA85738">
        <property type="protein sequence ID" value="ACA85738"/>
        <property type="gene ID" value="Swoo_1446"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1446"/>
    <dbReference type="eggNOG" id="COG2313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012201_0_1_6"/>
    <dbReference type="OMA" id="RKLGHRD"/>
    <dbReference type="OrthoDB" id="1294333at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046113">
        <property type="term" value="P:nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="PTHR42909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="SSF110581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 6" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="142"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="304" mass="32252" checksum="1861A401D7FCF295" modified="2008-04-29" version="1">MLEQYLDINPEVAAALAAGKPVVALESTIISHGMPYPQNVETALRVEQIIRDNGAIPATIAILKGRLKVGMTPDEIEYLGKAGLDVIKTSRRDIPFIVAKQVDGATTVASTMILAAMAGIKVFATGGIGGVHRGAEQTFDISADLQELANTDVAVVCAGAKSILDIGLTLEYLETQGVPVIGHQTDTLPAFYTRESDFGVDYRLDTPEQIADALKAKWAMGLKGGVVVANPIPQAHQLDRAMIDEVILDALAQMDEQGISGKASTPFLLAKVAEKTKGSSLKANIELVFNNAKLAAEIAVEYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK18</accession>
    <name>B1KK18_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transketolase central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2932"/>
    <dbReference type="EnsemblBacteria" id="ACA87205">
        <property type="protein sequence ID" value="ACA87205"/>
        <property type="gene ID" value="Swoo_2932"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2932"/>
    <dbReference type="eggNOG" id="COG0022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_1_6"/>
    <dbReference type="OMA" id="HSQMLTP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="2">
        <location>
            <begin position="7"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="36800" checksum="559885895C646B04" modified="2008-04-29" version="1">MSATNKLTIARAMAESLAQEMRTDPNVFIMGEDIAQLGGVFGNTRGLYTEFGEERIRDTPISETAFIGAGVGAAMDGMRPVVELMFVDFFGVCFDAIYNLMAKNIYFSGGHSNVPMVIMASTGGGYSDGGQHSQCLYATFAHLPGMKVIAPSNAYDAKGLLTAAIRDNSPVIYLFHKGLQGMGWLGTEPAAINQVPEENYQLEIGKAKTVISGTDITIVSIGMGVHHALKAAHELQKDDISIEVIDLCSLVPLDRQHIIESVNKTGRLIVVDEDYHSYGMSGEIFASVIEHDHTIFKTPPQRITYPDIPIPFSRPMEQWALPSTEKIIHACLTMKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK57</accession>
    <name>B1KK57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327014.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4436"/>
    <dbReference type="EnsemblBacteria" id="ACA88688">
        <property type="protein sequence ID" value="ACA88688"/>
        <property type="gene ID" value="Swoo_4436"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4436"/>
    <dbReference type="eggNOG" id="ENOG5032T1D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137857_1_0_6"/>
    <dbReference type="OMA" id="MCAGFYL"/>
    <dbReference type="OrthoDB" id="2040603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15372" checksum="0D0391590707FB66" modified="2008-04-29" version="1">MNGAGGTSGGIGQFFIGLIMMCGGFYMLLNAIKVTSSFGMGSRLYHVSNFGGFNITSGMIMIPFIFGVGIMFYNYKNILGWILTFGSLVALIFGVISSIQFRFTHMSAFDLIVILVLSIGGLGLFLRSFKALDQAYPDSSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK73</accession>
    <name>B1KK73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4452</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4452"/>
    <dbReference type="EnsemblBacteria" id="ACA88704">
        <property type="protein sequence ID" value="ACA88704"/>
        <property type="gene ID" value="Swoo_4452"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4452"/>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_1_3_6"/>
    <dbReference type="OMA" id="CHACTEA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="103"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="240" mass="26036" checksum="D154D3E0FC926CD8" modified="2008-04-29" version="1">MEDAVSENIERRRFLKCLGASSLILAPLGCSSVKEGESDANKPHYAMVFDQNKCTGCGECKEACNLANNLPEGKSRLLMEQHSGGLEGQSCPHCGKTTECGCERKFVRVSCQQCKNAPCVTVCPTGAAHRDEKTGIVTMDAAKCAGCKYCIAACPYDARFINKETDVADNCDFCLNSKLAIGELPACVQKCRYDALIFGDINDPTSYISKLLRVKDSVRIKPGFGTEPSLRYIPIVKLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH4</accession>
    <name>B1KKH4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324160.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1526"/>
    <dbReference type="EnsemblBacteria" id="ACA85814">
        <property type="protein sequence ID" value="ACA85814"/>
        <property type="gene ID" value="Swoo_1526"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1526"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022176_2_1_6"/>
    <dbReference type="OMA" id="IEVCNAS"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="494"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="622" mass="70891" checksum="23C3CCC300E24DA6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL6</accession>
    <name>B1KKL6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87233">
        <property type="protein sequence ID" value="ACA87233"/>
        <property type="gene ID" value="Swoo_2960"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2960"/>
    <dbReference type="eggNOG" id="ENOG502Z801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_968529_0_0_6"/>
    <dbReference type="OMA" id="PIEQTFY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="267" mass="31114" checksum="FFCBCD361A564EB2" modified="2008-04-29" version="1">MPMDYQPGISNNQIGKDRRVLTMKIVTRFGLTSPTIISWLYGIPHRLALEHLNKLVSEKLLSLVITHRSIDGRVYVLDYAGAKYAEELLSIAVYFRAGEPSLRVNQNTIMHDLMMQYVLLKGVHNRTKDNIAKPYWYSFVTEPEFKRLFKSNDVRNVDGIALESDGTIAAIEIEHSFKTKAARQTILLKWLYGLKHCYYSKVMLFSQSQQIFNDIKRLHNQLYEEMPTRFEKKTRQVLLSHEDAELLKARIVHRTVLCDELTNIFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKQ3</accession>
    <name>B1KKQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gluconate 2-dehydrogenase (Acceptor)</fullName>
            <ecNumber evidence="3">1.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.99.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325606.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2999"/>
    <dbReference type="EnsemblBacteria" id="ACA87270">
        <property type="protein sequence ID" value="ACA87270"/>
        <property type="gene ID" value="Swoo_2999"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2999"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008878_4_2_6"/>
    <dbReference type="OMA" id="GNTKIWG"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033717">
        <property type="term" value="F:gluconate 2-dehydrogenase (acceptor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="2">
        <location>
            <begin position="431"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="561" mass="62265" checksum="7689B1709225A56F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKU7</accession>
    <name>B1KKU7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327079.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88753">
        <property type="protein sequence ID" value="ACA88753"/>
        <property type="gene ID" value="Swoo_4502"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4502"/>
    <dbReference type="HOGENOM" id="CLU_1874025_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15469" checksum="A1FFE670FB1B42C0" modified="2008-04-29" version="1">MRTIFWRVAYEDEQLGEILKSKALVLPDLSRWPIAKNKNEEKIVSELKVGHFVLMANFNPNNEIGTVKGVGKITKNDVGSVEVEWKRPIPSWSLTPNAQGGVQEWRNEGVFCFDAEPAKRYKLQALTSKLFTAHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV2</accession>
    <name>B1KKV2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4507</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327084.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4507"/>
    <dbReference type="EnsemblBacteria" id="ACA88758">
        <property type="protein sequence ID" value="ACA88758"/>
        <property type="gene ID" value="Swoo_4507"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4507"/>
    <dbReference type="eggNOG" id="COG1585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116732_1_1_6"/>
    <dbReference type="OMA" id="ICRDNIA"/>
    <dbReference type="OrthoDB" id="1951939at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
            <begin position="57"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="16171" checksum="2FDD4FFE77C61C5F" modified="2008-04-29" version="1">MELTNPIIIWACIGLILMLAELVIPGGIVILLGGACLVVASALGIGLVEGLVQSLTLWFIASIVLLLGFRGLTQKLVGGDSHVDNTDEELDIYNQIATVKESIGPAQHAGRIEFQGTEWSALGDGSEIAVGTQVRIICRENIGLIVEPVNEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW4</accession>
    <name>B1KKW4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein Swoo_4519</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4519</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327096.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4519"/>
    <dbReference type="EnsemblBacteria" id="ACA88770">
        <property type="protein sequence ID" value="ACA88770"/>
        <property type="gene ID" value="Swoo_4519"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4519"/>
    <dbReference type="eggNOG" id="COG0217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062974_2_0_6"/>
    <dbReference type="OMA" id="CAKNGGF"/>
    <dbReference type="OrthoDB" id="1304328at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="242" mass="26984" checksum="62D75796EAC7105F" modified="2008-04-29" version="1">MGRAYQNRKESMAKTAGQKTRLYSRYGKEIYVCAKNGGFDPDGNLPLRQMIAKAKKDQVPAHVIERAIDKAKGGGGEDYETARYEGFSPGGAMVIVDCLTDNGKRTFTEVRQAFVKNDAKLGGPGTVGHMFDHQAVFVFKGEDEEAVLEMLIMADVDVTDVELEDGMITVYAPHTEFYKTKTALTEENSEAEFEVEEITFVPQTMTDITDPEVIEQFEKFLAALEDCDDVQNVYHNAELPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKX8</accession>
    <name>B1KKX8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable peptidoglycan glycosyltransferase FtsW</fullName>
            <shortName evidence="10">PGT</shortName>
            <ecNumber evidence="10">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cell division protein FtsW</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Cell wall polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Peptidoglycan polymerase</fullName>
            <shortName evidence="10">PG polymerase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ftsW</name>
        <name evidence="11" type="ordered locus">Swoo_4534</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Peptidoglycan polymerase that is essential for cell division.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="10">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SEDS family. FtsW subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327110.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4534"/>
    <dbReference type="EnsemblBacteria" id="ACA88784">
        <property type="protein sequence ID" value="ACA88784"/>
        <property type="gene ID" value="Swoo_4534"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4534"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029243_1_1_6"/>
    <dbReference type="OMA" id="KLWWSNL"/>
    <dbReference type="OrthoDB" id="1133883at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00913">
        <property type="entry name" value="PGT_FtsW_proteobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018365">
        <property type="entry name" value="Cell_cycle_FtsW-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013437">
        <property type="entry name" value="FtsW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02614">
        <property type="entry name" value="ftsW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00428">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="10 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="44848" checksum="2D389E6736B06806" modified="2008-04-29" version="1">MRSDERQLNLFGTSVTWSWPNLFKENEAPGLQLYDRTLLISVIGLICFGFVMVMSASMPEAQSLKGNPYHFVMRHLVFIIGSVIIAAVVLRIPMAMWQRFSPIFLLIVGIMLVAVPFVGHTVNGATRWLVIGPLRIQVAELAKLAFAIYMAGYLVRRHQEIRENAKGFYKPIAVFAVYAILILMQPDLGTVVVLFVGTVGLLFLAGARLLDFFALILTGIMAFVALVLLEPYRMRRVTSFMDPWQDPFGSGYQLTQSLMAYGRGDWFGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIIVVLTVLLFVALKAIKLGNLCIQIDKAFEGYLAYAIGIWFCFQTVVNVGASIGMLPTKGLTLPFISYGGSSLWVMTAAAMILIRIDHERRLSSIQAVQGKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY7</accession>
    <name>B1KKY7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327119.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88793">
        <property type="protein sequence ID" value="ACA88793"/>
        <property type="gene ID" value="Swoo_4543"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4543"/>
    <dbReference type="eggNOG" id="ENOG5031H49">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143533_0_0_6"/>
    <dbReference type="OMA" id="VEETEYM"/>
    <dbReference type="OrthoDB" id="2085075at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="95" mass="10891" checksum="4F4D56BBBBCDBEE0" modified="2008-04-29" version="1">MIGLDSLYAMLARPVQASVKRKRIVEETENSAGIAEDSHEAPQSQLPPNLERRRSLEDRRGTSRGDRRRKAKQEEELKDNKELLESPLPRIDIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ8</accession>
    <name>B1KKZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RarD protein, DMT superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4554</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327130.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4554"/>
    <dbReference type="EnsemblBacteria" id="ACA88804">
        <property type="protein sequence ID" value="ACA88804"/>
        <property type="gene ID" value="Swoo_4554"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4554"/>
    <dbReference type="eggNOG" id="COG2962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054508_1_0_6"/>
    <dbReference type="OMA" id="HRMVWSL"/>
    <dbReference type="OrthoDB" id="1391352at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="8"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="33035" checksum="ECE396F92B898D9D" modified="2008-04-29" version="1">MLSSEQNKGIASAICAYTLWGFAPLYFKLLDQVSATEILIHRVIWSFIFVTLLMMMFGGFSRLRQVLKRPKQLMVLTLTSVLIAGNWLLFIWAVNNDHMLDASLGYFINPLVNVMLGMVFLSERLRKLQWLAVILAGTGVLVQLISFGSIPLVSLGLASSFGLYGLLRKKVNVDAKTGLLVETAILFPIALLYLFANFGDSMTNLMSNELSLNLLLMAAGVVTTIPLLCFAAAAVRIPLSMLGFFQYIGPSIMFIMAITLYNEPFDLEKGITFGFIWSALIIFTIDMFYKRKPIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL76</accession>
    <name>B1KL76_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322766.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0116"/>
    <dbReference type="EnsemblBacteria" id="ACA84417">
        <property type="protein sequence ID" value="ACA84417"/>
        <property type="gene ID" value="Swoo_0116"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0116"/>
    <dbReference type="eggNOG" id="COG2849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_798990_0_0_6"/>
    <dbReference type="OMA" id="YEKGREW"/>
    <dbReference type="OrthoDB" id="1525899at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="351" mass="41198" checksum="15B00830A9E3E6DA" modified="2008-04-29" version="1">MSFNKPVKLSSNPIALIVTLLFFSGCEQVPTHPINEEELEQIECSETEEQGLTINQDCLTGYRGKPFTGIGVSTSMYGNHFNAAQYKDGLKHGFSFSANEVHLKFQGWFNQGLKDGEHLVYHYKSDKLRSRTIYQEGEKLTEDFYTEEGIINSFKRFDGEDIVESISYEKGREWIHTYFAQNGEKRQRWKRYYANGQLSSNGEFRDEDLKKLNEITYFFSGKIRTQFNYDRQSNRSQLDTYWPNGYRQSEKHYIYPSITLDGKVLRFCQENGQLQAIEHYRKNIEHGLFEQFYCNGQLQKREHYADGIIIDKQVKVFHENGQLMILRKLDGKGKEVSSKYYDETGKLTYQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL98</accession>
    <name>B1KL98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322788.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0138"/>
    <dbReference type="EnsemblBacteria" id="ACA84439">
        <property type="protein sequence ID" value="ACA84439"/>
        <property type="gene ID" value="Swoo_0138"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0138"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064247_0_0_6"/>
    <dbReference type="OMA" id="KQFDVFS"/>
    <dbReference type="OrthoDB" id="1620161at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021484">
        <property type="entry name" value="DUF3137"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11335">
        <property type="entry name" value="DUF3137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="336" mass="38927" checksum="227C424EEE1AFC4D" modified="2008-04-29" version="1">MNIVSFIFGAPIKPKRQSKPLVAVGDELTSLQAHYDEHIEPLTRKFENRRVASLKALRQRLYMSLAIFAGVLIISVLIDNQQRLGLPWPFFLLPLIPLIWWSSRPVSRYKSDVKQRVFPKIFRYFGDDFIFSSTHQMSLSALKRSKLLPSYDNASFEDYVQGTYKGVEIAINELELTKEVKRDKRRETQTVFNGVMVQLSCHKPFTGHTVVVKTRGGLINFLSDSFKSLSRVKLEDVRFEKQFDVFSSDQIEARYLLTVTFMERLQELASCFSGKIQCAFYDDKLLIMLASSEDRFELGSIFHGATFEYEFSQINKEMRQLFAMIEVLKLDEYTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA0</accession>
    <name>B1KLA0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multidrug export protein MepA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322790.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0140"/>
    <dbReference type="EnsemblBacteria" id="ACA84441">
        <property type="protein sequence ID" value="ACA84441"/>
        <property type="gene ID" value="Swoo_0140"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0140"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_0_2_6"/>
    <dbReference type="OMA" id="MILLFNT"/>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13143">
        <property type="entry name" value="MATE_MepA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045070">
        <property type="entry name" value="MATE_MepA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="464" mass="50323" checksum="C0DE487C4877A464" modified="2008-04-29" version="1">MHSYQSPSDQTSSSISRTFWRYAIPSVAAMLVNGLYQIVDGIFIGQYVGYQGLAGINMAWPIIYIFAGIGLMIGMGSGSLLSINRGENSLTGDDKKLVSTKVNNTLASALLLVIGFGLIGSIVLNLSVDTLLLMQGGSGQTLLMAQQYTTPFTWSLVFTILAAAIPILVRNDESPNIATGLMVMGACLNIVLDYLLIVQFNMALQGAAIATISAQISVSILGIGYFISSKTDFKFNASAFIFSPKLAGKIMILGASSFVMYLYTSFVFALHNRLFMEYGSSLTVGAFAIVGYLMVLYYFVAEGLGEGMQPPVSFFFGAREPKNIKRMFQLAAKVSISAGLLWVLILNLFPEAIIGLFNSEDRALMTETIVGIQLHLFAMFLDGFVVLAIMYFMAVNQGGRSLWISVGNMVVQLPFLFILPKVFGINGVWLAMPVSNLVIFAVVAPMVWRHLNSAIESGRELSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB7</accession>
    <name>B1KLB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324188.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1556"/>
    <dbReference type="EnsemblBacteria" id="ACA85842">
        <property type="protein sequence ID" value="ACA85842"/>
        <property type="gene ID" value="Swoo_1556"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1556"/>
    <dbReference type="eggNOG" id="ENOG5032R1X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069111_0_0_6"/>
    <dbReference type="OMA" id="YWAATYL"/>
    <dbReference type="OrthoDB" id="343485at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PTHR35870"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="329" mass="36721" checksum="1C407785F8E1F270" modified="2008-04-29" version="1">MEELKLLDLLLEKSGHYHPLYGDGLATHLPMVLTALDLLNASSIKLQHTFDESIKGLEEIGSLEGVTSVNGIDSNLGNSESFRSYLTYFKSELEQCGTQAVLKKSLPILISGVAASAFHGLIRLAYAIEANCQSEMAIALAYWSAEYQSFELNEETTNESLESILTQLSPLGENHKFSPGLIVDRMSEIGILLKNKGSITQPNIIDISTLREFTIKSFYLSDDFTLLHTVTGCHALSIVLPYLEDKQTALRELWKAIVVAYLSTGLRYQDKEITTVEKNINFSPIIEKALKSEDSHAIKLVYTCLCEYKNWNDPLYFTVSKRAILNSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB8</accession>
    <name>B1KLB8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324189.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85843">
        <property type="protein sequence ID" value="ACA85843"/>
        <property type="gene ID" value="Swoo_1557"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1557"/>
    <dbReference type="HOGENOM" id="CLU_1905331_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="14565" checksum="CE2095F98D841902" modified="2008-04-29" version="1">MVVEIISVIVILAVITIGYKVAPHRDLGKSKPFLAVFPKYKCLVSVTYNPDVLESKLEEFGFKKVGEKGEGVKFTRGSVLGELSVNLTKVDLHLSSANSTKTCLLVNASWVAAFDTGDHWILTKELAEKLENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH2</accession>
    <name>B1KLH2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar hook-associated protein 2</fullName>
            <shortName evidence="5">HAP2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Flagellar cap protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FliD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324243.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1611"/>
    <dbReference type="EnsemblBacteria" id="ACA85897">
        <property type="protein sequence ID" value="ACA85897"/>
        <property type="gene ID" value="Swoo_1611"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1611"/>
    <dbReference type="eggNOG" id="COG1345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015182_5_0_6"/>
    <dbReference type="OMA" id="TLEWQRD"/>
    <dbReference type="OrthoDB" id="883503at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009421">
        <property type="term" value="C:bacterial-type flagellum filament cap"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010810">
        <property type="entry name" value="Flagellin_hook_IN_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040026">
        <property type="entry name" value="FliD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010809">
        <property type="entry name" value="FliD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003481">
        <property type="entry name" value="FliD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30288">
        <property type="entry name" value="PTHR30288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07196">
        <property type="entry name" value="Flagellin_IN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07195">
        <property type="entry name" value="FliD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02465">
        <property type="entry name" value="FliD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="FliD_N" evidence="6">
        <location>
            <begin position="10"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="FliD_C" evidence="7">
        <location>
            <begin position="215"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="456" mass="47856" checksum="C843635C1C6F60B2" modified="2008-04-29" version="1">MALTATGIGSGLDINTIVGVLVDAEKVPKEAIFDKTEKTIDAKVSAIGTLKSALSTFQDALEKLKDGNNINQKSVSTGDSQFLTATADKTAQTGSYNIKVEQLATAHKVAGINVADPAAAVGEGSLDLTVNGNSFSVDVGAGDSLEDIAKSINDATDNVGVTATIITSDAGSRLVLSSDVEGPDSQITVAATDTVGTGLNDMFGGVNLTELQEAKPSIIHVDGQKITSQTNEVKGAITGVTLNLTDADINTSSTVKIELDKEGIKENITDFVDAYNSLIESIDKLSAYDTEKKTAAALQGDSMIRSIESQARNLISSRVTVDGETVALYDIGISADRYGKLSVDSTKLDKVIDEDIGSIEGLFATDTTGIAVQLDELVEGYVKTGGLIDSRNNAYTSDKQRLDDQREAFSLKMEQLQARLFKQFNAMDLVVGNLNQQAGGIISGLNSLPGVVKSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLM6</accession>
    <name>B1KLM6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325659.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3052"/>
    <dbReference type="EnsemblBacteria" id="ACA87323">
        <property type="protein sequence ID" value="ACA87323"/>
        <property type="gene ID" value="Swoo_3052"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3052"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047251_2_0_6"/>
    <dbReference type="OMA" id="CSMPGLL"/>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="6"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="37"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="33737" checksum="4C896FD589D5BDF6" modified="2008-04-29" version="1">MAKIGIALGSGAAKGWAHIGVLNGLAEMGIKPDKVSGCSIGALVGAAYANDQLDELETWVRSFSSWDVLGLMDLSWRKGGLIGGEKVFDVIQSRIGDLQIEQLHRPLIAVATDLYSGQEIWFKEGDLRHAIRASCSMPGILPPVKLGERWLVDGAVVNPVPVSVSRAMDVDVVIAVDLNGQKRGRMQVLPVDMACSKPSVEESVQAQEHQDTGFMDLLARGRDYVTNLTDKFTLGKGSNPGMLAVMSQSMDILEQRHKRARLMGDPPDICLIPDVADIGTMEFHRAEEAIAAGELAVKLARHQIEARLESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLN6</accession>
    <name>B1KLN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325669.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87333">
        <property type="protein sequence ID" value="ACA87333"/>
        <property type="gene ID" value="Swoo_3062"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3062"/>
    <dbReference type="eggNOG" id="ENOG5033U1V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1151185_0_0_6"/>
    <dbReference type="OrthoDB" id="1769466at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767468" evidence="1">
        <location>
            <begin position="19"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="241" mass="27727" checksum="A644A422AF8779A7" modified="2008-04-29" version="1" precursor="true">MQAIRLILLMVLSFATEATTWGESEVDDPIVEGEKCSVYEPLSYGGYIYNWPSKYDQVFWPLTDYNGIWFCEKSGFTSFIGDFSALTVSELAKIKKYLLENPPKDSSIHTKLALLEALYSLRDTDTAFKNRLLRVFARWHQHLENYDKANDYRRKALAGIELALQGDMSEFKHLEYLYLAANYSKQLGYKEASDRYISKLISSLGNIKSEDNRGYIEYLQKLYPDTNYIEAGGVLDPVLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ3</accession>
    <name>B1KLQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325686.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3079"/>
    <dbReference type="EnsemblBacteria" id="ACA87350">
        <property type="protein sequence ID" value="ACA87350"/>
        <property type="gene ID" value="Swoo_3079"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3079"/>
    <dbReference type="eggNOG" id="COG3883">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085088_0_0_6"/>
    <dbReference type="OMA" id="LMFKMVD"/>
    <dbReference type="OrthoDB" id="1594624at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016866">
        <property type="entry name" value="UCP028069"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11932">
        <property type="entry name" value="DUF3450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028069">
        <property type="entry name" value="UCP028069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767473" evidence="1">
        <location>
            <begin position="29"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="260" mass="28720" checksum="0C503E8A1B23D9DD" modified="2008-04-29" version="1" precursor="true">MSKVSNKTKIATALVGALALAGSNLVIADPLSNVQKADSKIHAEAATSQKKVDKYYDQAQDMAFEYAQVADTRESTKSYNDYVAGLVADQEATMKLIQDDINGVDKLRQGVVPLMFKMVDALEQFIALDLPFNLEARNARVERLRSTLNTAEVTLAEKYRLILDAYNIEREYGSKLNAQTGQLALDGKEILVDFLNFGRVALYAQSQDQKQAWMYNADSKGWDQLSDGYLRNLNKAIKQARGQGAPDMFALPIPAAEAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLU4</accession>
    <name>B1KLU4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Yip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325727.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3120"/>
    <dbReference type="EnsemblBacteria" id="ACA87391">
        <property type="protein sequence ID" value="ACA87391"/>
        <property type="gene ID" value="Swoo_3120"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3120"/>
    <dbReference type="eggNOG" id="ENOG502Z7KS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099801_0_0_6"/>
    <dbReference type="OMA" id="HPKEEWH"/>
    <dbReference type="OrthoDB" id="1606932at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="7"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="198" mass="21649" checksum="489D88F59416C8E8" modified="2008-04-29" version="1">MILNHLMGLYTHPKEEWHTIEQNHEALKSSLSHVLLVALIPVICTFFASTEIGWNLGVGDPLFLTQQSAMLMSVGMYFGLIAGVFGLAYLAFWMAKTFDADPSFTQALELASYTATPLFMVGLAALYPSIWFVMVIGLLGLTYSVYLLYTGVPIIMNIPEEKGFIYASSVVTAGLVLLVALMASSVILWSMGLGPIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM66</accession>
    <name>B1KM66_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cytochrome c oxidase subunit 2</fullName>
            <ecNumber evidence="17">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ordered locus">Swoo_0178</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 17">Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="17">Binds a copper A center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="17"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322828.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0178"/>
    <dbReference type="EnsemblBacteria" id="ACA84479">
        <property type="protein sequence ID" value="ACA84479"/>
        <property type="gene ID" value="Swoo_0178"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0178"/>
    <dbReference type="eggNOG" id="COG1622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036876_2_2_6"/>
    <dbReference type="OMA" id="HAFMPIA"/>
    <dbReference type="OrthoDB" id="1654242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13912">
        <property type="entry name" value="CcO_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034210">
        <property type="entry name" value="CcO_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014222">
        <property type="entry name" value="Cyt_c_oxidase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02790">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02866">
        <property type="entry name" value="CoxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 17" id="KW-0186">Copper</keyword>
    <keyword evidence="9 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 15 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="24" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 16 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766824" description="Cytochrome c oxidase subunit 2" evidence="20">
        <location>
            <begin position="20"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="22">
        <location>
            <begin position="18"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="21">
        <location>
            <begin position="114"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="23">
        <location>
            <begin position="275"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="23">
        <location>
            <begin position="415"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ACA84479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="513" mass="55177" checksum="AE8CF660711C42B2" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM67</accession>
    <name>B1KM67_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322829.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0179"/>
    <dbReference type="EnsemblBacteria" id="ACA84480">
        <property type="protein sequence ID" value="ACA84480"/>
        <property type="gene ID" value="Swoo_0179"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0179"/>
    <dbReference type="eggNOG" id="COG5404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1569639_0_0_6"/>
    <dbReference type="OMA" id="PNIGYKQ"/>
    <dbReference type="OrthoDB" id="1941503at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051782">
        <property type="term" value="P:negative regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004596">
        <property type="entry name" value="Cell_div_suppressor_SulA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03846">
        <property type="entry name" value="SulA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="18483" checksum="134CF45B40D70437" modified="2008-04-29" version="1">MNTLIGNGPRHPGLWIDHQTHYSSQLQSSTISSVASSTQGREELKQVSSQLATLSQQGQWIVLISPPNIGYKKLLAEAGVRMNRVLLVHAKDEVETLWAMEKALTSGTSSAVLCWTQSLDARDSRRLQIVAKSARALGVVIEDANSSSQVNTHNPIIDSALQPSLFSSVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM95</accession>
    <name>B1KM95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mandelate racemase/muconate lactonizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322857.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0207"/>
    <dbReference type="EnsemblBacteria" id="ACA84508">
        <property type="protein sequence ID" value="ACA84508"/>
        <property type="gene ID" value="Swoo_0207"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0207"/>
    <dbReference type="eggNOG" id="COG1441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_0_1_6"/>
    <dbReference type="OMA" id="YEANRDG"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="146"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="351" mass="38993" checksum="D7927BB6AC1797DE" modified="2008-04-29" version="1">MKINTLELYQYQLPLDKCLPVGKQRIDSRKGVILSLELLDEAMTPRIEQVEIAPLSGLDIEGNPIQDFSQETLEQIIDELAITLPQLIGKPVDLLLEQSKKTQYPSLAFGLSLLHAKINGQLTGHHISLQNMKSVPLIYRAQNEALSVLHDRVRSLASEVHSIKVKVAQTSLEEEIKLIHEILAIRPALKLKLDANRGFTLEQAIEFAACLPLHAIEYIEEPCITPQDNPAFYQAIEMPWALDESLNDPDYQFEMQDGLTALVVKPMLIGSLEKLQRLQSEAEHAGVRFILSSSLESSLGIEALAKLSQSMTPDEIPGLDTLGAFSADILISSGKPHLLGLDSIKLINRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMA1</accession>
    <name>B1KMA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor plug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0213</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322863.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0213"/>
    <dbReference type="EnsemblBacteria" id="ACA84514">
        <property type="protein sequence ID" value="ACA84514"/>
        <property type="gene ID" value="Swoo_0213"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0213"/>
    <dbReference type="eggNOG" id="COG4773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_15_2_6"/>
    <dbReference type="OMA" id="VANTHQD"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="53"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="285"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="776" mass="85278" checksum="1F78B0BFC2B99D2D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME5</accession>
    <name>B1KME5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1657"/>
    <dbReference type="EnsemblBacteria" id="ACA85943">
        <property type="protein sequence ID" value="ACA85943"/>
        <property type="gene ID" value="Swoo_1657"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1657"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_12_2_6"/>
    <dbReference type="OMA" id="YLIEIGN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="15439" checksum="EAFFF18DDA4112DD" modified="2008-04-29" version="1">MNGRVTIYGSSYEMFSAEPYLVTLGDNVFISVGASFVCHDGSTLPFRKNIPDLELAGRINVGDNIFIGKGALVLPGVSIGNNCIVGANAVVAKDVPNNSVVAGNPARVIKSTDDFLAKAKRNSLKIGNLYGKDKVDAYKKIFDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG9</accession>
    <name>B1KMG9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3 7">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1682</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324313.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1682"/>
    <dbReference type="EnsemblBacteria" id="ACA85967">
        <property type="protein sequence ID" value="ACA85967"/>
        <property type="gene ID" value="Swoo_1682"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1682"/>
    <dbReference type="eggNOG" id="COG1898">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090940_1_1_6"/>
    <dbReference type="OMA" id="KTPEIAC"/>
    <dbReference type="OrthoDB" id="1618609at2"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="6">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="182" mass="20786" checksum="E128B3DB58A362B6" modified="2008-04-29" version="1">MKVISTPISDVKILAPQVFTDERGSFHEIFRDDWFIEHVADVRFVQENQSSSKQSTLRGLHYQTAQTQGKLIRVISGEVFDVVVDLRRSSPTFGHCFSTTLSANNKHQLWVPIGFAHGFYVTSESAELVYKCTDYYAPQFECSILWNDPELAIDWPIASDCNPLLSEKDRKGVLFQDAFVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI1</accession>
    <name>B1KMI1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase</fullName>
            <ecNumber evidence="4">2.4.1.187</ecNumber>
            <ecNumber evidence="4">2.7.8.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.187" evidence="4"/>
    <dbReference type="EC" id="2.7.8.6" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324325.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1694"/>
    <dbReference type="CAZy" id="GT26">
        <property type="family name" value="Glycosyltransferase Family 26"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85979">
        <property type="protein sequence ID" value="ACA85979"/>
        <property type="gene ID" value="Swoo_1694"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1694"/>
    <dbReference type="eggNOG" id="COG1922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023240_0_0_6"/>
    <dbReference type="OMA" id="GMEWICR"/>
    <dbReference type="OrthoDB" id="1759731at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047244">
        <property type="term" value="F:N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047360">
        <property type="term" value="F:undecaprenyl-phosphate galactose phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="498"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="692" mass="77508" checksum="D34836D0B5ED61AA" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ5</accession>
    <name>B1KMJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324339.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1708"/>
    <dbReference type="EnsemblBacteria" id="ACA85993">
        <property type="protein sequence ID" value="ACA85993"/>
        <property type="gene ID" value="Swoo_1708"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1708"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_3_6"/>
    <dbReference type="OMA" id="DHLVMIT"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="30916" checksum="9F19381DBA741701" modified="2008-04-29" version="1">MVRMGVDLGGTKIEIVALNDGGKELFRKRIPTPREYPATLDAIEALVNEVESTLGETGTVGVGIPGVVSPYSGLVKNANSTWINGHPLDVDLGERLNREVRVANDANCFAVSEAVDGAAAGKGVVFGVIIGTGCGAGFAINGKVHAGGNGIGGEWGHNPLPWMTSDEFNTTSCFCGNRDCIETFISGTGFVRDFKAAGGQANSGIEIASLVENGDKLAKAAFERYIDRLARSLAHVINVLDPDVIVLGGGVSNIAAIYPLLPEVLPKYVLGGECRTPVVQNMYGGSSGVRGAAWLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP2</accession>
    <name>B1KMP2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative serine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3149</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325756.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3149"/>
    <dbReference type="EnsemblBacteria" id="ACA87420">
        <property type="protein sequence ID" value="ACA87420"/>
        <property type="gene ID" value="Swoo_3149"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3149"/>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052043_1_1_6"/>
    <dbReference type="OMA" id="MLVVCWI"/>
    <dbReference type="OrthoDB" id="369689at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004694">
        <property type="entry name" value="Hydroxy_aa_transpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00814">
        <property type="entry name" value="stp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="430" mass="46700" checksum="C9189A91086192D1" modified="2008-04-29" version="1">MDTVISKTETASTQIEVKSSWSKSDTLWVLGLYGTAVGAGTLFLPINAAQGGLIPLIMMALLALPMTFFAHQGMTRFVLSGSKPGAGITEVVEEHFGVGMGKVITLLYFFAIYPILLVYSVALTNTVESFLLHQLNITPPNRATLALVLIIALIAVVRLGEQLIIKAMSVLVFPFVAVLLMLSFYLIPYWNTAIFNNIVPAEGGISTIVMALWLILPVMVFSFNHSPVISSFAVDRKKAHGDNAEKQCSRILAMSHILMVATVMFFVFSCVLSLSPANLAEAKAQNVSILTYLANHFNTPIIAYAAPIVAIIAITKSFFGHYIGASEGFNGLIIKSARSRKKEISSVTLNRFTTAFMLLTTWAVATINPNILGMIESLGGPIIALLLFIMPMYAIKKVPAMKQYSGQLSNFFVVIIGLISISAIFYSLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV9</accession>
    <name>B1KMV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3217"/>
    <dbReference type="EnsemblBacteria" id="ACA87487">
        <property type="protein sequence ID" value="ACA87487"/>
        <property type="gene ID" value="Swoo_3217"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3217"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098637_4_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="108" mass="11368" checksum="61A57C76682110F7" modified="2008-04-29" version="1">MKRRISGFTLIELVVVIIILGLLAVVALPKFIDLQGDARRAAMDGQFAAFENAVKLYHSGWLAEGNTGAIDKLASFGEGNVASSPAGYPYSTSGISNGTNGKTFEACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ7</accession>
    <name>B1KMZ7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8 9">Elongation factor Tu</fullName>
            <shortName evidence="8">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tuf</name>
        <name evidence="11" type="ordered locus">Swoo_4704</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327272.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4704"/>
    <dbReference type="EnsemblBacteria" id="ACA88954">
        <property type="protein sequence ID" value="ACA88954"/>
        <property type="gene ID" value="Swoo_4704"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4704"/>
    <dbReference type="eggNOG" id="COG0050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_0_1_6"/>
    <dbReference type="OMA" id="ERPHCNV"/>
    <dbReference type="OrthoDB" id="621774at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="10"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="394" mass="43262" checksum="E6345916D484FD21" modified="2008-04-29" version="1">MAKEKFERNKPHVNVGTIGHVDHGKTTLTAAISAVLTKTYGGEARDFAQIDNAPEERERGITINTSHIEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVPFIIVFMNKCDMVDDEELLELVEMEVRELLSEYEFPGDDLPVIQGSALKALEGEADWEAKILELAEALDTYIPEPERAIDGAFILPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKDTTKTTCTGVEMFRKLLDEGRAGENCGVLLRGTKREDVERGQVLAQPGSITPHTTFQSEIYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNVQMTVTLICPIAMDEGLRFAIREGGRTVGAGVVAKIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN79</accession>
    <name>B1KN79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flavocytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0275</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322925.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0275"/>
    <dbReference type="EnsemblBacteria" id="ACA84576">
        <property type="protein sequence ID" value="ACA84576"/>
        <property type="gene ID" value="Swoo_0275"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0275"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011398_4_5_6"/>
    <dbReference type="OMA" id="RIADYCA"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022271636" evidence="4">
        <location>
            <begin position="31"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_2" evidence="5">
        <location>
            <begin position="46"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="506" mass="54561" checksum="4ED3DBBD75EE067D" modified="2008-04-29" version="1" precursor="true">MSNKDLLGRRNFIKGMGAAAGVAMAAPALAVSENANGVKWDKEVEVLIIGSGFAGLAAAIEATRKGAKDVHIFEKMSYFGGNSAINGGLFAAPDTPMQKQEGVKDSVDTMVADQLAAGRGIADEALLRHVAEHAVEALQMTLDAGSEYHPYLQQLGGHSVARTYQTTVSCGAGITQPLLQECRKLGVHTHNRAKFDGFILDEKGGVVGVKMREGYYFDKPESGKLVRIKARRGVIMATGGFAQNINMRMAQDPTLTAEVGCTNAPGATGEGMFEMFRLGAVPVHLAHIQSGPWASPDEGGFGYVSNYSIYNFPHSIAIDRLTGKRFMNEIADRKTRADAELNCRDAQGNPLPPILITSYEDSKQHPNTKKVLKYNVGWKFDSIDALAKHFDVPLAPLKKQIAEYNDYVKTQSDPQFGKNMTEAKGKFIQAPFTVVRLWPKVHYCQGGVQINTNAEVKDSLTGKPISGLYAAGEVCGGIHGVSRLGSCSIPECMVMGMTAARIMMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KND4</accession>
    <name>B1KND4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetylglutamate kinase</fullName>
            <ecNumber evidence="8">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">NAG kinase</fullName>
            <shortName evidence="8">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argB</name>
        <name evidence="10" type="ordered locus">Swoo_0330</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322980.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0330"/>
    <dbReference type="EnsemblBacteria" id="ACA84631">
        <property type="protein sequence ID" value="ACA84631"/>
        <property type="gene ID" value="Swoo_0330"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0330"/>
    <dbReference type="eggNOG" id="COG0548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053680_1_1_6"/>
    <dbReference type="OMA" id="EGLYEDW"/>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 8" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="9">
        <location>
            <begin position="7"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="46"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="261" mass="27060" checksum="A949B6ECBB3C418F" modified="2008-04-29" version="1">MTQSNKALVIKVGGALLQCEMGMARLMDTAAKMLAAGQKLILVHGGGCLVDEQLSANGMKTEKLDGLRVTPAEQIPVIVGALAGTSNKVLQAAAIKAGVTSIGMSLGDGDMVTAQVKDERLGFVGEVAPKSSAYLDFILSQGWLPIVSSIAIDEAGQLLNVNADQAATVLAKLVDAKLVLLSDVSGVLDGKGQLILSLNRAQVDDLTHKGVIEKGMKVKVEAALDVAELMGQAVQVASWRSAEQLLALSNGESVGTQIQPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNT6</accession>
    <name>B1KNT6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc metalloprotease</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3274</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325880.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3274"/>
    <dbReference type="EnsemblBacteria" id="ACA87544">
        <property type="protein sequence ID" value="ACA87544"/>
        <property type="gene ID" value="Swoo_3274"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3274"/>
    <dbReference type="eggNOG" id="COG0750">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025778_0_2_6"/>
    <dbReference type="OMA" id="QYMVGFG"/>
    <dbReference type="OrthoDB" id="1395197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00054">
        <property type="entry name" value="TIGR00054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="209"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="461" mass="50429" checksum="21153F6FEE0FF065" modified="2008-04-29" version="1">MIDFLWNLGSFIIALGILITAHEYGHFWVARRCGVRVERFSIGFGKAIWRKVGKDGTEYVIALIPLGGYVKMLDERVDDVPEELKEQAFNRKSVWQRIAIVAAGPLANFIFAIIALYFMYLIGVPSIKPVIDTTTKNTPAELIQVQEPMQITSVGGKTVRNWEEVTYALVGHIGDPEIALTLRPMSQNSEVNDSTPLNLGKTYTLDTKNWQFDPDKESPITSLGLGIYRPAITPVLGLVSPDGAAAAAGIEVGDSLVSMNGEPYQSWDGFVEVIKSSANKPVELMVRRGGEQLKFIVTPHERKGAQGEIEGVIGIAPTQAAWPESMKLQLEYGFIESFAVAADKTWQLVDVSFKMIGKLISGDVSVKNLSGPISIAQGAGSSANYGLVYFLGFLALISVNLGIINLLPLPVLDGGHLLYYFVEVITGRPVPEKVQEIGFRFGAAMLLMLMSIALFNDFSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP21</accession>
    <name>B1KP21_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4803</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327369.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89052">
        <property type="protein sequence ID" value="ACA89052"/>
        <property type="gene ID" value="Swoo_4803"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4803"/>
    <dbReference type="eggNOG" id="ENOG5032EX2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2958213_0_0_6"/>
    <dbReference type="OMA" id="LTEFHEP"/>
    <dbReference type="OrthoDB" id="2069098at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="69" mass="8353" checksum="4C9686B68AAAE6BA" modified="2008-04-29" version="1">MESIISIDELLGNIGTPESKLRRYQACLNEFDRLNYDDPFIRQIREEATRLEQKIKESKTQNTWFKFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH1</accession>
    <name>B1KPH1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sucD</name>
        <name evidence="7" type="ordered locus">Swoo_1840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324470.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1840"/>
    <dbReference type="EnsemblBacteria" id="ACA86124">
        <property type="protein sequence ID" value="ACA86124"/>
        <property type="gene ID" value="Swoo_1840"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1840"/>
    <dbReference type="eggNOG" id="COG0074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052104_0_0_6"/>
    <dbReference type="OMA" id="VIICITE"/>
    <dbReference type="OrthoDB" id="1081709at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="30004" checksum="7A2C4C39CB2EE363" modified="2008-04-29" version="1">MSVLINKDTKVICQGFTGGQGTFHSEQAIDYGTQMVGGVSPGKGGQVHLNLPVFNTVKDAVAETGATASVIYVPAPFCKDAIFEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPLTEAIVMIGEIGGTAEEEAADYIKANVTKPVVSYIAGVTAPEGKRMGHAGAIIAGGKGTAEDKFAALEAAGVTTVRSLADIGKALRTKTGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPV4</accession>
    <name>B1KPV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3368"/>
    <dbReference type="EnsemblBacteria" id="ACA87637">
        <property type="protein sequence ID" value="ACA87637"/>
        <property type="gene ID" value="Swoo_3368"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3368"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_8_4_6"/>
    <dbReference type="OMA" id="DQSEPYT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="15853" checksum="42E249586CD9DCE0" modified="2008-04-29" version="1">MNTHTSKLIHTMIRVRDLDSSIAFYQTALGLEIKEQFIFDGFTLTYLGNQATDFELELTYNHDVDNDYSHGSGYGHIAVCVEDIEESFRRLILLDMQPTDIKHLKHKDTHLASFFFIQDPDGYKIEFLQRSKRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ15</accession>
    <name>B1KQ15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carboxyl-terminal protease</fullName>
            <ecNumber evidence="5">3.4.21.102</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327445.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4879"/>
    <dbReference type="MEROPS" id="S41.004"/>
    <dbReference type="EnsemblBacteria" id="ACA89128">
        <property type="protein sequence ID" value="ACA89128"/>
        <property type="gene ID" value="Swoo_4879"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4879"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017295_3_0_6"/>
    <dbReference type="OMA" id="TFNQVDW"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="85"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="401" mass="44330" checksum="F7C33C0B39B12B9C" modified="2008-04-29" version="1" precursor="true">MSQLIRYLSFTLLGLALGVSLTLSSQENAEQAQSRLNYPLLLDIIDTVETYYVTEFTQDELIAAAIEGIFAKLDPYSNFLDQQEFSNIRDANKGEYFGFGVEIATEDNKITIITPFANSPADLAGIEPGDQILKLNNEPVDSNRLDYLLKEIKRHSQNNLPILLTLSHTGMDTEFEVTLIPSVISIQSVSAKVIEDQIGYIRLASFQDNSTEELVKQLTQWQDVRLSGIILDLRNNPGGLLDQAIKIADIFLSKGRIVSTEGRFFDANSEYYASPQTMLSNIPMTILINKGSASASEVLAAALQENHRAKVIGETSFGKGTVQSLIPTLIEGNAIKLTIAKYTTPNGRDINSKGIEPDIKLDLTTVTNNKNVPIIDEIIIQDESTQDKILNSAITWIKTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB5</accession>
    <name>B1KQB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323119.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0472"/>
    <dbReference type="EnsemblBacteria" id="ACA84770">
        <property type="protein sequence ID" value="ACA84770"/>
        <property type="gene ID" value="Swoo_0472"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0472"/>
    <dbReference type="eggNOG" id="COG3672">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085651_0_0_6"/>
    <dbReference type="OMA" id="DIDLWHE"/>
    <dbReference type="OrthoDB" id="1500682at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010319">
        <property type="entry name" value="Transglutaminase-like_Cys_pept"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39327">
        <property type="entry name" value="PTHR39327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06035">
        <property type="entry name" value="Peptidase_C93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="235" mass="27208" checksum="98E9B6EF4E3874EC" modified="2008-04-29" version="1" precursor="true">MKDRLTHNLTYIKVCRFTLIAMVLVASCLYASPTQKLNKGHITSTLESRYGERAGKRVRAWFKVLDEAKNLSEREKITKVNTFFNLFRFVDDIKLWGESNYWATPMEFIGVNGGDCEDFSIAKYFTLLQLGVEEDKLRITMVKATTVNQYHMVLAYYETPGSIPLVLDNLDRKIKPATQRKDLLPVYSFNGRQLWLNKEKGRGVLAGSSKKLAKWNDLKHRLGVERLRKPKLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI1</accession>
    <name>B1KQI1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324566.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1936"/>
    <dbReference type="EnsemblBacteria" id="ACA86220">
        <property type="protein sequence ID" value="ACA86220"/>
        <property type="gene ID" value="Swoo_1936"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1936"/>
    <dbReference type="eggNOG" id="COG0530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_188465_0_0_6"/>
    <dbReference type="OMA" id="SLEYPWA"/>
    <dbReference type="OrthoDB" id="2102876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019099">
        <property type="entry name" value="Uncharacterised_PGPGW_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09656">
        <property type="entry name" value="PGPGW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="75" mass="8310" checksum="FBFAB2E075C01FB5" modified="2008-04-29" version="1" precursor="true">MLRKTAITVLGGGLTLLGAALLILPGPAWLLLPIGLAILSLEYPWAKIWLRKSQKQFSASAAWLDRKILLRRMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQV0</accession>
    <name>B1KQV0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Thiopurine S-methyltransferase</fullName>
            <ecNumber evidence="4 9">2.1.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Thiopurine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tpm</name>
        <name evidence="10" type="ordered locus">Swoo_3438</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.</text>
            <dbReference type="EC" id="2.1.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.67" evidence="4 9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326041.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3438"/>
    <dbReference type="EnsemblBacteria" id="ACA87706">
        <property type="protein sequence ID" value="ACA87706"/>
        <property type="gene ID" value="Swoo_3438"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3438"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085515_1_0_6"/>
    <dbReference type="OMA" id="MEASFWH"/>
    <dbReference type="OrthoDB" id="2049098at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008119">
        <property type="term" value="F:thiopurine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00812">
        <property type="entry name" value="Thiopur_methtran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022474">
        <property type="entry name" value="Thiopur_S-MeTfrase_Se/Te_detox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025835">
        <property type="entry name" value="Thiopurine_S-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023956">
        <property type="entry name" value="Thiopurine_S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03840">
        <property type="entry name" value="TMPT_Se_Te"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 9 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="23795" checksum="547E056B9A06C98B" modified="2008-04-29" version="1">MKASFWHERWERGEIAFHEQEINCFLAEHLSRLGVRRGGRILVPLCGKTRDIEHLLSCGYQVVGVELNQQAVEALFIALGLTPNVTKVGDFTLYRAANIDLFVGDIFALSSELVGAVDGIYDRAALVALPFEMRKRYSSHLIDITCGAPQLLVIYTYDQTLMDGPPFSISCDEVELHYSENYCVNQLDSRDAPGGIRGKISAIESAWLLIKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQV7</accession>
    <name>B1KQV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Periplasmic/7TM domain sensor diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3445</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326048.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3445"/>
    <dbReference type="EnsemblBacteria" id="ACA87713">
        <property type="protein sequence ID" value="ACA87713"/>
        <property type="gene ID" value="Swoo_3445"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3445"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_485494_0_0_6"/>
    <dbReference type="OMA" id="YYAPYEF"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011623">
        <property type="entry name" value="7TMR_DISM_rcpt_extracell_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07695">
        <property type="entry name" value="7TMR-DISM_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767305" evidence="2">
        <location>
            <begin position="25"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="420"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="556" mass="63490" checksum="647B273ADF7E4A52" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRA5</accession>
    <name>B1KRA5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2028</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324658.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2028"/>
    <dbReference type="EnsemblBacteria" id="ACA86312">
        <property type="protein sequence ID" value="ACA86312"/>
        <property type="gene ID" value="Swoo_2028"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2028"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071415_2_1_6"/>
    <dbReference type="OMA" id="TGSWHVG"/>
    <dbReference type="OrthoDB" id="2062716at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="6">
        <location>
            <begin position="5"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="17883" checksum="B470EB9F75166B9C" modified="2008-04-29" version="1">MKQVSSVLFVCMGNICRSPTAEAVLRMKAKQSGLELEIDSAGTLAYHQGESPDPRSVAAGERRGFSFKGMKARQVIDEDFAHFDLILAADVQNIRELQSRCPEQYLDKIKLMLSHCEEGEEPSAQVLEVPDPYYGKGDGFERVLDLLESSCEQLIRQIKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRL5</accession>
    <name>B1KRL5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis protein UbiU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiU</name>
        <name evidence="2" type="ordered locus">Swoo_3516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms an heterodimer with UbiV.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U32 family. UbiU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326113.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3516"/>
    <dbReference type="EnsemblBacteria" id="ACA87780">
        <property type="protein sequence ID" value="ACA87780"/>
        <property type="gene ID" value="Swoo_3516"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3516"/>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011540_3_2_6"/>
    <dbReference type="OMA" id="HVAINTF"/>
    <dbReference type="OrthoDB" id="1264653at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02232">
        <property type="entry name" value="UbiU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043692">
        <property type="entry name" value="UbiU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01276">
        <property type="entry name" value="PEPTIDASE_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="333" mass="36948" checksum="FC69E585FD7663C9" modified="2008-04-29" version="1">MELLCPAGNLASLKTALNAGADAVYLGLKNDTNARSFAGLNFTPKKLQEAAQYTKQQGKKIFLTINTFPKPGEEKRWYEAVDIAANTGVDALIIADLSLLDYAHSHYPHLPLHLSVQASATNLGALKLYKEEFNIQRAVLPRVLSMKQVRDLSKVTPVDLEVFAFGSLCIMAEGRCHLSSYVTGQSPNTGGSCSPAKHVRWQEEGENRLTRLNEVLIDKSGIDEQMGYPVVCKGRYTTEHNSTPTHLLESPTSLNTLSLLPELAKANVVSLKIEGRQRSPAYVEQVTQVWRRAIDTYLNNPDNFQTQVEWDRALAKVSEGQTTTLGAYERTWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRM7</accession>
    <name>B1KRM7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MgtE intracellular region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3528</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326125.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3528"/>
    <dbReference type="EnsemblBacteria" id="ACA87792">
        <property type="protein sequence ID" value="ACA87792"/>
        <property type="gene ID" value="Swoo_3528"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3528"/>
    <dbReference type="eggNOG" id="COG2239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037408_1_1_6"/>
    <dbReference type="OMA" id="YFREATQ"/>
    <dbReference type="OrthoDB" id="1239195at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="210"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="49959" checksum="470D8E480E382B7B" modified="2008-04-29" version="1">MVELNNENDATQLDIADVVQLLTEAEGQAQSEVFDEILEGAESGTVALLLESLPLDERYDRWQQVDDNERVTVLSLMRAEPRLGILEQMSLEESDLLFAQLSPEDLIDWSDHLPDSLTERALAKMGLRQRKHFELYDQYSDNEIGRYADHQMLVLDLKSSIGQAQNFFRRINLDCNDKIFLVDENDKYQGDVRRFDIFKHDPSEPLASLLSEDNRALAADTSLLEAAESMEHSREVEMPIVDDEGVLIGRVTLRTATILVREHYEAQLMATAGMDESDDLFAPIVKGAQRRAIWLGINLLTAFLASATIGLFEDVLTQVVALAILMPIVASMGGIAGSQSLTLMIRGMAMGQVSPGNRLSLLKNELGIGSVNGILWAGIIGAVAAWWFGDNTIGMVMACAILVNMLVAAIAGVLVPIILQKCNQDAALSGSVILTTVTDVVGFFTFLGVASILYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRQ6</accession>
    <name>B1KRQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326154.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3557"/>
    <dbReference type="EnsemblBacteria" id="ACA87821">
        <property type="protein sequence ID" value="ACA87821"/>
        <property type="gene ID" value="Swoo_3557"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3557"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_46_6"/>
    <dbReference type="OMA" id="RFCCAFQ"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="278"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="420"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="677" mass="75587" checksum="7CEBC0D54BE1ED9B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD66</accession>
    <name>B1KD66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326234.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3639"/>
    <dbReference type="EnsemblBacteria" id="ACA87901">
        <property type="protein sequence ID" value="ACA87901"/>
        <property type="gene ID" value="Swoo_3639"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3639"/>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068418_1_0_6"/>
    <dbReference type="OMA" id="GYMRRET"/>
    <dbReference type="OrthoDB" id="834480at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021243">
        <property type="entry name" value="DUF2804"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35868">
        <property type="entry name" value="PTHR35868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10974">
        <property type="entry name" value="DUF2804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="355" mass="39587" checksum="12FEF7426D8734D7" modified="2008-04-29" version="1">MGISQAQAAMIKTVIAPEEIINSRGKPIFGHFDGPVSSLALDKFKYFNEMDRQASNLARYFHYKQFQFVSIVTPHFIIGVAIADIRYVGSAFCYLFDIKKNRLVETSWLKPLGLGYSLTPSPMEGTAKISGGKGAVVFNLHEGIWSLSINTSTIHAELTLSPPVLSLPMVMCNPTGYSGWTYTQKHNGLTLKGQLTVNDEPQPLNRALASYDFSAGYMRRETSWRWACINAHSDEGIIGLNLAAGVNETGCNENVFWVNGERHLLGPVHFDFGRLRGEAQGGTQGESWRIYSGNGQVELTFSSLNCRQEKLNLLLLKSNFRQYIGYYSGYIIDNSGVKHILNNVLGLTEDHFARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD0</accession>
    <name>B1KDD0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the extradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323278.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0635"/>
    <dbReference type="EnsemblBacteria" id="ACA84931">
        <property type="protein sequence ID" value="ACA84931"/>
        <property type="gene ID" value="Swoo_0635"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0635"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084417_1_1_6"/>
    <dbReference type="OMA" id="QHIAFQV"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000486">
        <property type="entry name" value="Xdiol_ring_cleave_dOase_1/2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00082">
        <property type="entry name" value="EXTRADIOL_DIOXYGENAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="4 6 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="7">
        <location>
            <begin position="6"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="182" mass="20784" checksum="4F77BCCEBA55C8DC" modified="2008-04-29" version="1">MINIERIHHVAYRCNDAKETVEFYRDKLNMDFLVAIAEDKVPSTKAPDPYMHLFLDAGNGNILAFFELPNSPKMDRDRNTPEWVQHIAFRVKDTAALLEAKRELEGKGVEVLGITKHGIIESIYFFDPNGHRLELTCVTGTSAQFKELKKVAPAMLEEWSVTKRAPKHAAWLHEEEFEGSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD6</accession>
    <name>B1KDD6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Curli production assembly/transport component CsgE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in the biogenesis of curli organelles.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0641"/>
    <dbReference type="EnsemblBacteria" id="ACA84937">
        <property type="protein sequence ID" value="ACA84937"/>
        <property type="gene ID" value="Swoo_0641"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0641"/>
    <dbReference type="eggNOG" id="ENOG5032THU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158669_0_0_6"/>
    <dbReference type="OMA" id="YRTHFGR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018900">
        <property type="entry name" value="Curli_CsgE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10627">
        <property type="entry name" value="CsgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767264" description="Curli production assembly/transport component CsgE" evidence="4">
        <location>
            <begin position="21"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14838" checksum="FE8D7E025855A818" modified="2008-04-29" version="1" precursor="true">MKKWVYLLLFLFTFPTAAVAVEDDIEISGLVIDRTLTRFGKDFGFYYSGYWRDLTFTQGFNVTLYETVFPQAGTQLTLEVNGKAIYRTHFGRRANPVKERAEQAILLTIDHIAQIKANAVTGELASAEDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDP3</accession>
    <name>B1KDP3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SpoVR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324785.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2156"/>
    <dbReference type="EnsemblBacteria" id="ACA86440">
        <property type="protein sequence ID" value="ACA86440"/>
        <property type="gene ID" value="Swoo_2156"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2156"/>
    <dbReference type="eggNOG" id="COG2719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010179_3_0_6"/>
    <dbReference type="OMA" id="NSNPCYA"/>
    <dbReference type="OrthoDB" id="507759at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007390">
        <property type="entry name" value="Spore_V_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30029">
        <property type="entry name" value="PTHR30029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04293">
        <property type="entry name" value="SpoVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="508" mass="59726" checksum="2D3826BF6F3B4125" modified="2008-04-29" version="1">MDNKKKRTPLDDGPDWTFDLLQTYLTEIEKVAAHYKLDSYPNQIEVITAEQMMDAYAGIGMPIGYTHWSFGKKFIETEQSYKRGQMGLAYEIVINSDPCIAYLMEENTITMQALVMAHASFGHNSFFKNNYLFKTWTDASSIIDYLVFAKKYISQCEEAHGAEKVELIIDSCHALMNYGVDRYKRPSEISFKEEQLRQKDREEYLQSQVNDLWRTIPLNQSDAKEKPRSHFPEEPQENILYFIEKHAPLLKPWEREIVRIVRKMGQYFYPQKQTQVMNEGWATFWHYTILNHLYDDGLVTDRFMMEFLQNHTNVVAQPSYNSPYYSGINPYALGFNMFVDIRRICENPTEEDKRWFPDIAGSDWLETLHFAMQNFKDESFISQYLSPNIIRQFKLFGVLDDDKKNYLSVSAIHDDQGYKDIRQMLSQQYNLSNLEPNIQVQSVEVKGDRSLTLRYIPTNRVPLAKSRHEVVKHLHRLWGFDVRLEELNLDGERTVIAACPDQEDEEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE01</accession>
    <name>B1KE01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326335.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3744"/>
    <dbReference type="EnsemblBacteria" id="ACA88003">
        <property type="protein sequence ID" value="ACA88003"/>
        <property type="gene ID" value="Swoo_3744"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3744"/>
    <dbReference type="HOGENOM" id="CLU_2452946_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="8709" checksum="8B4002E2E84C4883" modified="2008-04-29" version="1">MQLFIGLVLCIIGIFSLIKLHIFVGIIFLFLGAGVLQGLRSGKSFDLTTRTAHKRGGTSYGDSGLGGGDGGFGGGSGDGGGSCGGGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE12</accession>
    <name>B1KE12_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3755"/>
    <dbReference type="EnsemblBacteria" id="ACA88014">
        <property type="protein sequence ID" value="ACA88014"/>
        <property type="gene ID" value="Swoo_3755"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3755"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="GFHIYYS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="30"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="319" mass="36478" checksum="829F7B633EFC89FC" modified="2008-04-29" version="1">MYINIQLRLITSIYKDYFHMTMNKLFDGVVIFTQVVKSGGFSAAAEALGHSTSYVSKEVNKLESRLGVRLLNRTTRSIGLTPEGQAYHQQCLQLVQDAEQAVQLITQHDVSPKGHLKISSPVGFANNYLRPILSQYMLNYPNVNLELDLNDRRVDVISEGYDLVIRASQNLDESSLICRKIYSCKAYTVATPEYLSKHGRPYHPQELAKHNCLCYSNLKLPTRWHYSDKQGKSFFVDVRQKVLCNSGEMEFAMTLDGLGICRLPEFYLQDTLETGKLEILFPQYPTTDIDVFVVYPSRKHLSPKVRAFIDLVVERLPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEK4</accession>
    <name>B1KEK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326351.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3760"/>
    <dbReference type="EnsemblBacteria" id="ACA88019">
        <property type="protein sequence ID" value="ACA88019"/>
        <property type="gene ID" value="Swoo_3760"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3760"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_4_2_6"/>
    <dbReference type="OMA" id="GYIAKPN"/>
    <dbReference type="OrthoDB" id="1306955at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="19793" checksum="7D023E51D2CCB1E0" modified="2008-04-29" version="1">MSNIVYIAASLDGYIADKNGSVDWLHELPNPEGSDMGFGELMERVDGLVMGRNTFEMVLSFGVDWPYNKPVFVLSNRLTQLPEGVEDKAFLLNGTPKEVMSKINALGYNNLYIDGGVTIQNFLKADLIDEMIITTIPVLLGGGSPLFGDLLEPLKFSYVKSEPLLDCVVKNYYFRARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES5</accession>
    <name>B1KES5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326420.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3831"/>
    <dbReference type="EnsemblBacteria" id="ACA88090">
        <property type="protein sequence ID" value="ACA88090"/>
        <property type="gene ID" value="Swoo_3831"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3831"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016232_0_0_6"/>
    <dbReference type="OMA" id="IRYFGIE"/>
    <dbReference type="OrthoDB" id="956262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3857" evidence="2">
        <location>
            <begin position="70"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="285"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="672" mass="76617" checksum="BECABCF799B01C98" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEY8</accession>
    <name>B1KEY8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323486.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0844"/>
    <dbReference type="EnsemblBacteria" id="ACA85139">
        <property type="protein sequence ID" value="ACA85139"/>
        <property type="gene ID" value="Swoo_0844"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0844"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_3_1_6"/>
    <dbReference type="OMA" id="LMEPELY"/>
    <dbReference type="OrthoDB" id="154149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="436"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="646" mass="73816" checksum="C78F6DCF881AF77E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF02</accession>
    <name>B1KF02_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Cysteine desulfurase</fullName>
            <ecNumber evidence="4 7">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323500.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0859"/>
    <dbReference type="EnsemblBacteria" id="ACA85153">
        <property type="protein sequence ID" value="ACA85153"/>
        <property type="gene ID" value="Swoo_0859"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0859"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_5_6"/>
    <dbReference type="OMA" id="HKLCGPT"/>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="24"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="403" mass="44065" checksum="26FF55E200F79300" modified="2008-04-29" version="1">MDFHHLRAQFPTLEQTLAGYPLCYLDTAATSQKPKQVLNAMARYYENDNANVHRAAHQLSSRATSNYETVRDKVCHFIKAKQREEIIFTHGTTESINLVAYGLTGQIKSGDLILIDTAAHHANIVPWQELAKRTGAIIKPIPLDSECRLDETAYEHLLQENPFIVALSHVSNALGTLNPVNRLVALAKQVGAITLVDGAQAIAHLDVDVQAIGCDFYVFSGHKMYGPTGVGVLYGRFDILDSLMPLMTGGEMIKTVSFEATEFNQLPNRLEPGTPPIAEVIGLGAAIDFLSALPREVIAKQEAELLSYLQTQLKQLGDITLYGANTSNIGAVAFNLADEHHQDVGILLDQQGIAVRCGHHCAMPLMQSLGLKGCCRASLGVYTSKEDIDRFIEAMASVKEMLL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-11-03" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF36</accession>
    <name>TRMN6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA1(Val) (adenine(37)-N6)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.223</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA m6A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_0893</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43160"/>
            <dbReference type="Rhea" id="RHEA-COMP:10369"/>
            <dbReference type="Rhea" id="RHEA-COMP:10370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.223"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.223" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323534.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KF36"/>
    <dbReference type="SMR" id="B1KF36"/>
    <dbReference type="STRING" id="392500.Swoo_0893"/>
    <dbReference type="EnsemblBacteria" id="ACA85187">
        <property type="protein sequence ID" value="ACA85187"/>
        <property type="gene ID" value="Swoo_0893"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0893"/>
    <dbReference type="eggNOG" id="COG4123">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061983_0_0_6"/>
    <dbReference type="OMA" id="NQYTEAF"/>
    <dbReference type="OrthoDB" id="1027015at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016430">
        <property type="term" value="F:tRNA (adenine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01872">
        <property type="entry name" value="tRNA_methyltr_YfiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022882">
        <property type="entry name" value="tRNA_adenine-N6_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000387432" description="tRNA1(Val) (adenine(37)-N6)-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01872"/>
        </source>
    </evidence>
    <sequence length="243" mass="26935" checksum="1D6150E544857E82" modified="2008-04-29" version="1">MAFTFKQFHIDDHGCGMPVSTDGVLLGAWAPLSKAENLLDIGAGSGLLSLMAAQRSEAQITAVELDDTAFHACNKNFIASKWQSRLNLVYASVQEFCNQHTDGNNAQFDHIICNPPYFKGGTQSSNRLRAQARHTDSLTFHALLEVITKLLAATGTASLILPSQSMTPFIEEVEKSELWMNQLTNISDSRFKAPHRHLFTLKHKATKLAEDDTVITNNLCIKEPDASYTPEMIALITGFYLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF37</accession>
    <name>B1KF37_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Branched-chain amino acid transport system carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0894</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the transport system for branched-chain amino acids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the branched chain amino acid transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0894"/>
    <dbReference type="EnsemblBacteria" id="ACA85188">
        <property type="protein sequence ID" value="ACA85188"/>
        <property type="gene ID" value="Swoo_0894"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0894"/>
    <dbReference type="eggNOG" id="COG1114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036807_0_1_6"/>
    <dbReference type="OMA" id="AFAFSYH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004685">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_Livcs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30588">
        <property type="entry name" value="PTHR30588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05525">
        <property type="entry name" value="Branch_AA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00796">
        <property type="entry name" value="livcs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="449" mass="47429" checksum="2B019F673462BD38" modified="2008-04-29" version="1">MMGRKVQDKQMTIADTLGLGFMTFAFFLGAGNLIFPPLAGFLSGENMNLAMLGFLITAVTLPLITLIAVAKANGKIMGLLPPLAATVFAVAIYIVIGPAFAAPRAGLVAYEMGFKPFLADSSATFMLAGITLNISQLIYSVIFFGGAMLLALYPGKLLDSVGKILTPIMLALLVALAASVFMTPGAEISHAVGDYQSNPLTKGILEGYNTMDTLASLIFGMLIIDILRRKGVSDSKAQTKYLIQAAFIAAAGLAFVYISLFYLGATGGDIAAGADNGGVILTNYVNREFGEFGKILLAAVVTLACLTTVIGLVTACAEFFNELIPSLSYRTFVIIISLICATVANVGLSQLISISVPVLYTIYPVAIALVAVTFLTEKFSMPEFSHRIVLSVALVFGVIDGLKAAGVNMDLFNFMPLHSEGMAWLLPTGLTIIACLLVKKPKTDPLLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF91</accession>
    <name>B1KF91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324974.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2353"/>
    <dbReference type="EnsemblBacteria" id="ACA86632">
        <property type="protein sequence ID" value="ACA86632"/>
        <property type="gene ID" value="Swoo_2353"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2353"/>
    <dbReference type="eggNOG" id="ENOG502ZCFT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091612_0_0_6"/>
    <dbReference type="OMA" id="FKPTIWI"/>
    <dbReference type="OrthoDB" id="1411229at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22576" checksum="30F08EE015F3F8C8" modified="2008-04-29" version="1">MSSNVEITYINKSMNKDLPTIFVFTKNETPTFDALKEGVAWRVIPDIGRASSSQFNFPIETSVGATWQGGQNKTQVLDSTIGKRYTVSKDDTGVVLAANGNASDTKSIDVNNDVNVPNGISAELYKDGKLMMTKNIVGFGQKATFVLKPRLYWGVASEIQESQLLNSAVLNTDKFFEQDLEGVTKVTVSLNGNAESGYNFKIENQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF98</accession>
    <name>B1KF98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PepSY-associated TM helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324981.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2360"/>
    <dbReference type="EnsemblBacteria" id="ACA86639">
        <property type="protein sequence ID" value="ACA86639"/>
        <property type="gene ID" value="Swoo_2360"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2360"/>
    <dbReference type="eggNOG" id="COG3182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_787315_0_0_6"/>
    <dbReference type="OMA" id="WWRTRRT"/>
    <dbReference type="OrthoDB" id="1656356at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="353" mass="39848" checksum="AB60F43AA0235917" modified="2008-04-29" version="1" precursor="true">MIKILKTLHNWIGFIISLVMLIVLTTGIYLGSVDLLKRLDDKNQQYQVLTHERKAEIASQVLASYPEVSGVKLPTEMLPYVEAYTRQKSIYLTSELDEIATQVKDKDSLQSWMFWFHRNFQLSDPGKHVNAVSAILATVIMFIGLYLWWLIRKGFRWKQTLPKNGKNSALIKSHIQLGLLFSIPLLVMSISGAYITYGSWGDSTLDDNREKPVLAQADNWQAQILAAQSLWPNSELVSVSKPRKAEATGYIYSLSFNGDNLLGLLQTDTIKIDLNTGRLESAQTFSDKGLAYQLKYSARFLHDGARMPTWYLLLLIISSIVGTLMVGFVLVTFTRKEIVGRIKAKAAVRLQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF99</accession>
    <name>B1KF99_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324982.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2361"/>
    <dbReference type="EnsemblBacteria" id="ACA86640">
        <property type="protein sequence ID" value="ACA86640"/>
        <property type="gene ID" value="Swoo_2361"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2361"/>
    <dbReference type="eggNOG" id="COG4922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073327_1_0_6"/>
    <dbReference type="OMA" id="CEEDWAR"/>
    <dbReference type="OrthoDB" id="1598464at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="PTHR38436"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="247" mass="28516" checksum="1145E10F088C2789" modified="2008-04-29" version="1">MEGIRDGNMIEALDKYTGERYTQHSTGVGDGKEGFMEFFAPFLERNPKRDIQVVRAIEDGQYVFVHVYQSLNDGEAKWVTADLFDTDDNDRMIEHWDVIAAFEEKTLSGRTMVDGPTEVEDLDKTDENKTIVQAFFDDVLLGRKFDKATKYISSKQYDQHNPKVGDGLVGVIKHFETKKCEKNSRYVKLHHLIGQGNFVVTFSHTLVSGEDWAFFDIFRLKDSMIVEHWDVQEKILSPEQWNNSGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL2</accession>
    <name>B1KFL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Deoxyribodipyrimidine photolyase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326517.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3929"/>
    <dbReference type="EnsemblBacteria" id="ACA88187">
        <property type="protein sequence ID" value="ACA88187"/>
        <property type="gene ID" value="Swoo_3929"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3929"/>
    <dbReference type="eggNOG" id="COG3046">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031632_1_0_6"/>
    <dbReference type="OMA" id="GMSQYAD"/>
    <dbReference type="OrthoDB" id="215545at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007357">
        <property type="entry name" value="PhrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04244">
        <property type="entry name" value="DPRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="531" mass="61516" checksum="75C7114CC15F058E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG24</accession>
    <name>B1KG24_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325073.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2454"/>
    <dbReference type="EnsemblBacteria" id="ACA86731">
        <property type="protein sequence ID" value="ACA86731"/>
        <property type="gene ID" value="Swoo_2454"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2454"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_4_1_6"/>
    <dbReference type="OMA" id="FAAWDTY"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02149">
        <property type="entry name" value="NfsB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033878">
        <property type="entry name" value="NfsB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="218" mass="24416" checksum="2EA63B3BB150F4B4" modified="2008-04-29" version="1">MTHPIIKDLNQRHTAKKYDASKRISQSVLEIIYEAMRLSASSINSQPWKFIVIESVEAKQRMHETFANKYQFNQPHIKAASHIILFAHNPSYTRNDYANVVDKGIEDGRTKPQDREQAFGGYAFAELNTDANGNNAAWTKSQTYLALGNTMHVLARLGIDSTPMEGVDSELIGEIFKAELDGFVCEVALAAGYHHSEEDYNAALPKSRLAMQDVLTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG64</accession>
    <name>B1KG64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326531.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88201">
        <property type="protein sequence ID" value="ACA88201"/>
        <property type="gene ID" value="Swoo_3944"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3944"/>
    <dbReference type="eggNOG" id="ENOG5032RUG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160774_1_0_6"/>
    <dbReference type="OMA" id="NVEEYCI"/>
    <dbReference type="OrthoDB" id="1896101at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021724">
        <property type="entry name" value="DUF3297"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11730">
        <property type="entry name" value="DUF3297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="82" mass="9312" checksum="C2BC52F7D6A2A387" modified="2008-04-29" version="1">MNDTTSQPTLPDRLSVNPRSPHHVAAIFEHDIGIKVNGKERFDVEEYCISESWVKVPSSKALDRRGQPLLMTIKGTVEAFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGA5</accession>
    <name>B1KGA5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PBPb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326572.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3985"/>
    <dbReference type="EnsemblBacteria" id="ACA88242">
        <property type="protein sequence ID" value="ACA88242"/>
        <property type="gene ID" value="Swoo_3985"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3985"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064076_3_1_6"/>
    <dbReference type="OMA" id="FLPWKRC"/>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764433" description="PBPb domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="33"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="29549" checksum="5B2ADE718A8EE31B" modified="2008-04-29" version="1" precursor="true">MSLKTACIVVLMLGWLVPPVFGADEKKTLNIVSTNYPPFYSDSYRRNGAVGYIVATAFGRRGYHVSHKFYPFTRATLLVKTGKADGIVGLWYRKEREEWAEYSQPIVPLNIVLYKRKDRDISYEQLSDLQGLRIGIGRGYANPAPFTQAKLFTEESSSDELNMKKLFLGRVDLVLIGRELARYIIRTGPDDYADAFEEVGVPLSTEVFHFGASKQIPGYQNLIREFNLGLESMRQDGTLDKVLKEYKITSNIGLTPLSVSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE7</accession>
    <name>B1KGE7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5-oxoprolinase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">3.5.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.2.9" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326613.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4028"/>
    <dbReference type="EnsemblBacteria" id="ACA88284">
        <property type="protein sequence ID" value="ACA88284"/>
        <property type="gene ID" value="Swoo_4028"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4028"/>
    <dbReference type="eggNOG" id="COG0145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002157_1_2_6"/>
    <dbReference type="OMA" id="NRGHDPR"/>
    <dbReference type="OrthoDB" id="327092at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="2">
        <location>
            <begin position="23"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="220"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="711" mass="78352" checksum="9BD2DC5399A7EC2B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK9</accession>
    <name>B1KGK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323683.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85337">
        <property type="protein sequence ID" value="ACA85337"/>
        <property type="gene ID" value="Swoo_1044"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1044"/>
    <dbReference type="eggNOG" id="ENOG5030FVV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2556407_0_0_6"/>
    <dbReference type="OMA" id="WFFWEFL"/>
    <dbReference type="OrthoDB" id="2039674at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="82" mass="9696" checksum="CFE5CC4AE1FC7469" modified="2008-04-29" version="1">MLIGSIAELFFWFFWEFLLSFILYTTGAIVLRLISFGRVRKPLFMPSIFSNEKRLAKNDFFSAYVSGFFFYLILLAFIIWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL0</accession>
    <name>B1KGL0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323684.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1045"/>
    <dbReference type="EnsemblBacteria" id="ACA85338">
        <property type="protein sequence ID" value="ACA85338"/>
        <property type="gene ID" value="Swoo_1045"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1045"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151283_0_0_6"/>
    <dbReference type="OMA" id="RNWLHFG"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="16066" checksum="2333F2D3F0E75F91" modified="2008-04-29" version="1">MIHLEHLNLVVTDIEKTLKFYQAAFPHWKVRGGGEASWHGKKRNWVHFGDDYQYLTFNDDGVGENRDLTGHQVGLAHFAFVTSDIDSVMTQLAEAGFNLDKDGAVDEYRKNVYYLDPNGYEVEFVQYLSDTPSLRNRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM3</accession>
    <name>B1KGM3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1058</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1058"/>
    <dbReference type="EnsemblBacteria" id="ACA85351">
        <property type="protein sequence ID" value="ACA85351"/>
        <property type="gene ID" value="Swoo_1058"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1058"/>
    <dbReference type="eggNOG" id="COG1180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044176_1_0_6"/>
    <dbReference type="OMA" id="YHFYPGS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027596">
        <property type="entry name" value="AmmeMemoSam_rS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01101">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04337">
        <property type="entry name" value="AmmeMemoSam_rS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="96"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="42882" checksum="9272BE1ECA246657" modified="2008-04-29" version="1">MKFSPKKDSGNNHVVTQKSVAQVQSDSSSIVDTRYWHALDDGRIQCDLCPRHCQLREGKRGVCFIRQNIDSEIKLTSYGRSSGFCVDPIEKKPLNHFYPGSSVLSFGTAGCNLCCKFCQNWDISKSRHFDTLGSQASPELLAATAKKMGCKSVAFTYNDPVIFHEYAIDVAQACHEIGINSVAVTAGYICPDPRVEFFNFMDAANVDLKGFTQEFYHKICSGNLSDVLDTLLYLKHETQVWFEITTLLIPDENDSVRELEQQTQWIVDNLGPNVPLHFSAFHPDFHMLKKTRTPVSTLMRAREIALKQGLNYVYTGNVHDSAGGSSYCPSCHQRVIERDWYKLGEYCLDSAGHCHHCGESISGRFDGAPGHFGHRRIPIRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM5</accession>
    <name>B1KGM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III chi subunit HolC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323699.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1060"/>
    <dbReference type="EnsemblBacteria" id="ACA85353">
        <property type="protein sequence ID" value="ACA85353"/>
        <property type="gene ID" value="Swoo_1060"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1060"/>
    <dbReference type="eggNOG" id="COG2927">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131584_0_0_6"/>
    <dbReference type="OMA" id="WQFEPSA"/>
    <dbReference type="OrthoDB" id="1575254at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007459">
        <property type="entry name" value="DNA_pol3_chi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036768">
        <property type="entry name" value="PolIII_chi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38767">
        <property type="entry name" value="PTHR38767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04364">
        <property type="entry name" value="DNA_pol3_chi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102400">
        <property type="entry name" value="SSF102400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="17735" checksum="1A3FEC67862CFD6A" modified="2008-04-29" version="1">MTQTLFYLMPTEPRSSGTALEQMFHLACELAQQAFIKQQLVYFHCQDREQAYAIDELLWQFEPRSFVPHNLKGEGPTTGAPVEIGFDNLGPNKNRHLLINLADQVPSFAVNFGQIIDFVANDTGHKAIARERYRQYRSLGVTLNTQDLAKQPLNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN0</accession>
    <name>B1KGN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323704.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85358">
        <property type="protein sequence ID" value="ACA85358"/>
        <property type="gene ID" value="Swoo_1065"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1065"/>
    <dbReference type="eggNOG" id="ENOG5033UFT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1418900_0_0_6"/>
    <dbReference type="OMA" id="FEDRIYF"/>
    <dbReference type="OrthoDB" id="1567591at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="22209" checksum="4B7D19D157F5C408" modified="2008-04-29" version="1">MIFNNISAFEQRMIVQGVDVAFFTIQYHNCAIETAYSRIQKKFLFAFVDHNLGFTCSLNGDYANGYINHRDAVEQLAACRNHGGFDPIHFYEFLDNQLPHVNFTEVTPIQYARVVGKAVSNFEDRIYFNHWRRANISDKQEKKTIELMGHEVLKFCKDNGLTPVFYPHPTVRTLQAFSDFNQDYLNHGLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN1</accession>
    <name>B1KGN1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BOF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323705.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85359">
        <property type="protein sequence ID" value="ACA85359"/>
        <property type="gene ID" value="Swoo_1066"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1066"/>
    <dbReference type="eggNOG" id="COG3111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118907_1_0_6"/>
    <dbReference type="OMA" id="KHLMSRE"/>
    <dbReference type="OrthoDB" id="1644884at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036700">
        <property type="entry name" value="BOBF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005220">
        <property type="entry name" value="BOF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04076">
        <property type="entry name" value="BOF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101756">
        <property type="entry name" value="SSF101756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764858" description="BOF domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="BOF" evidence="2">
        <location>
            <begin position="24"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="12835" checksum="9060006150E372DA" modified="2008-04-29" version="1" precursor="true">MRKIVLISALLFASSSVLAAQSPETKGGFTGPSSVAVKTVEVALEAKDDTQVLLTGHIVSGLGGEEYQFKDDTGTIIIEIDNRDWNGIEVTPETKIVIHGEVDSGWSYTTIDVDTVQLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGQ7</accession>
    <name>B1KGQ7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-methylisocitrate lyase</fullName>
            <shortName evidence="3">2-MIC</shortName>
            <shortName evidence="3">MICL</shortName>
            <ecNumber evidence="3">4.1.3.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">(2R,3S)-2-methylisocitrate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">prpB</name>
        <name evidence="5" type="ordered locus">Swoo_2499</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.</text>
    </comment>
    <comment type="function">
        <text evidence="3">Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3 4">Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.30" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325117.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2499"/>
    <dbReference type="EnsemblBacteria" id="ACA86776">
        <property type="protein sequence ID" value="ACA86776"/>
        <property type="gene ID" value="Swoo_2499"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2499"/>
    <dbReference type="eggNOG" id="COG2513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027389_3_2_6"/>
    <dbReference type="OMA" id="QTELWNK"/>
    <dbReference type="OrthoDB" id="1485205at2"/>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01939">
        <property type="entry name" value="PrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012695">
        <property type="entry name" value="PrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02317">
        <property type="entry name" value="prpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="42"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="119"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="206"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="31969" checksum="73CA3199FD4D73C9" modified="2008-04-29" version="1">MSAGKKFRQALADNKPLQIVGTINAYSAMMAKQIGHQAIYLSGGGVANASYGLPDLGMTSLNDVIVDVQRITSACDLPLMVDIDTGWGGAFNIAKTIRDMEKAGAAAVHMEDQVAQKRCGHRPNKEIVSTEEMVDRIKAAVDARTDPDFFIMARTDSFAQEGIEAAIERAKAYVAAGADGIFAEAVKTEEHYRAFSEALDVPILANITEFGQTELWNKAELGEWGADMVLYPLSAFRAMNKAAEMVYTSILENGDQKAVVDSMQTRMDLYNYLGYHDYEQKLDSLFAEGKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV5</accession>
    <name>B1KGV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325165.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2547"/>
    <dbReference type="EnsemblBacteria" id="ACA86824">
        <property type="protein sequence ID" value="ACA86824"/>
        <property type="gene ID" value="Swoo_2547"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2547"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_55_6"/>
    <dbReference type="OMA" id="HYIGIYE"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="322"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="464"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="722" mass="81754" checksum="99DEC5D6B2DE6164" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV8</accession>
    <name>B1KGV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal-5'-phosphate-dependent protein beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2550"/>
    <dbReference type="EnsemblBacteria" id="ACA86827">
        <property type="protein sequence ID" value="ACA86827"/>
        <property type="gene ID" value="Swoo_2550"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2550"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046285_0_0_6"/>
    <dbReference type="OMA" id="ESIFEQM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="23"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="353" mass="39212" checksum="7178CD43B786BF4A" modified="2008-04-29" version="1">MTNSWVNTAVEKIESDYQRSADTHLIKLDIPQLTGIDIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTTIIESSSGSTAVSEAYFARMLGLPFIAVMPKSTAKRKIQQIEFYGGTCHFVNHSSEIYAASEQLATQLNGHYMDQFTYAERATDWRGNNNIANSIFEQMTLEPHPIPKWIVMSPGTGGTSATIGRYIRYQQLDTQLCVVDPEHSVFYDYFTTGDKSLTSCHGSKIEGIGRPRAEPSFIPGVIDHMEKIPDAASVATIYWLEKLIGRKAGPSTGTNLYGALNIACDMLAKGQQGSIVTLLCDSGERYLDSYYNPDWVNDNIGELTEYEAKLAQFNLTASLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH44</accession>
    <name>B1KH44_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326685.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88356">
        <property type="protein sequence ID" value="ACA88356"/>
        <property type="gene ID" value="Swoo_4100"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4100"/>
    <dbReference type="eggNOG" id="ENOG5031H15">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1524133_0_0_6"/>
    <dbReference type="OMA" id="TWEREGE"/>
    <dbReference type="OrthoDB" id="2188448at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767350" evidence="2">
        <location>
            <begin position="21"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="176" mass="19991" checksum="D6356F942C7215C3" modified="2008-04-29" version="1" precursor="true">MKVNVLPLLLLASLSFSSIANEVDKMVEFSVTQMKRMGEFKSLSSATGVSETRLEKGFRAALTRCLKNHNMQGDGSELDACMSREVPSATGLSAAQLDTWEREGEVQMPSEKLLDEMDLINEKILQLEDKEDLTAVDEKQIIELENKLMQLSKKQRELQMQEMKDIASDFEEYHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH68</accession>
    <name>B1KH68_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326709.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4124"/>
    <dbReference type="EnsemblBacteria" id="ACA88380">
        <property type="protein sequence ID" value="ACA88380"/>
        <property type="gene ID" value="Swoo_4124"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4124"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="WPMEPFK"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="33407" checksum="A2E9D70E4EAA3D33" modified="2008-04-29" version="1">MPDLNGMMLFAAVVRAKGFSQAAREIGMPKSTISRKVAQLEEQLGVRLLQRDTRNLSLTQVGALFFQHCTSISDEIEAAKATIENTHNDVSGSLRVAIPVSFSQELIANLCSSFMRLYPNIELDVQFTDREVGLVGEGYDIAIKYGPLQSSDLVARLLLERQPILVASPGYLKANGTPATPQELMEHSGILLGTSRSAPIWPLGKGARKTMVSFKRKVRVNSAVMVKQLVLDDFGIAMLSNSVCKNELASGSLVPLLQEWPIEPIKVYGVYSSRRQLAANISVFLDFFTKRFNSHESLQSLMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH92</accession>
    <name>B1KH92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323746.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1107"/>
    <dbReference type="EnsemblBacteria" id="ACA85400">
        <property type="protein sequence ID" value="ACA85400"/>
        <property type="gene ID" value="Swoo_1107"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1107"/>
    <dbReference type="eggNOG" id="COG2035">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055621_0_0_6"/>
    <dbReference type="OMA" id="PIPVWSF"/>
    <dbReference type="OrthoDB" id="1426624at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007163">
        <property type="entry name" value="DUF368"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37308">
        <property type="entry name" value="PTHR37308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04018">
        <property type="entry name" value="DUF368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="315" mass="34256" checksum="7775099C157EEB2F" modified="2008-04-29" version="1">MNYLLTYLKGMAMGAADVVPGVSGGTIAFITGILDTLLESIRRINPKLISVIREQGVKQAFEYINGPFLVCVFGGILTSIFSLSKLITYLLETHPIPVWSFFFGLILISVVHMLKQVKGFSFIRLVLFALGTVFAWGITMLSPIALEMTYLNIFIGGSIAICAMLLPGISGSFILLLLGLYPSVLAAAKNFDITILAIFASGCIFGLLTFSHLLSALLRKFHDGTLIFLTGLMLGTLGKIWPWKEVLTWRTNSSGQQVPLLEQNLSPLQFEQITGQPAHIAWAVAALICGVALVWGLELFAARNGMANVNQDKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH94</accession>
    <name>B1KH94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323748.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1109"/>
    <dbReference type="EnsemblBacteria" id="ACA85402">
        <property type="protein sequence ID" value="ACA85402"/>
        <property type="gene ID" value="Swoo_1109"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1109"/>
    <dbReference type="eggNOG" id="ENOG502ZVYH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2119444_0_0_6"/>
    <dbReference type="OMA" id="TCTIRAE"/>
    <dbReference type="OrthoDB" id="1769576at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022090">
        <property type="entry name" value="DUF3634"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12321">
        <property type="entry name" value="DUF3634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12979" checksum="555459DA8F8B4641" modified="2008-04-29" version="1">MTPDVLKVIFILVGLFLVYKLIFSGKKGLTIFEMHFKDGRLISHKGKIPEKFQKECRAIAKSEKLTCSVRCEKSGAVRLHVSANVSDGVTQRIRNVFPFEYYDKKKVDNSRQAG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF1</accession>
    <name>CCA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Multifunctional CCA protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">CCA-adding enzyme</fullName>
                <ecNumber evidence="1">2.7.7.72</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">CCA tRNA nucleotidyltransferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="1">tRNA CCA-pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="1">tRNA adenylyl-/cytidylyl-transferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="1">tRNA nucleotidyltransferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="1">tRNA-NT</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">2'-nucleotidase</fullName>
                <ecNumber evidence="1">3.1.3.-</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">2',3'-cyclic phosphodiesterase</fullName>
                <ecNumber evidence="1">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Phosphatase</fullName>
                <ecNumber evidence="1">3.1.3.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">cca</name>
        <name type="ordered locus">Swoo_1166</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14433"/>
            <dbReference type="Rhea" id="RHEA-COMP:10465"/>
            <dbReference type="Rhea" id="RHEA-COMP:10468"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:74896"/>
            <dbReference type="ChEBI" id="CHEBI:83071"/>
            <dbReference type="EC" id="2.7.7.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Magnesium is required for nucleotidyltransferase activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="1">Nickel for phosphatase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Can also form homodimers and oligomers.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">A single active site specifically recognizes both ATP and CTP and is responsible for their addition.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="1"/>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EC" id="3.1.4.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323805.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHF1"/>
    <dbReference type="SMR" id="B1KHF1"/>
    <dbReference type="STRING" id="392500.Swoo_1166"/>
    <dbReference type="EnsemblBacteria" id="ACA85459">
        <property type="protein sequence ID" value="ACA85459"/>
        <property type="gene ID" value="Swoo_1166"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1166"/>
    <dbReference type="eggNOG" id="COG0617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015961_1_1_6"/>
    <dbReference type="OMA" id="GWTFHGH"/>
    <dbReference type="OrthoDB" id="2018439at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052928">
        <property type="term" value="F:CTP:3'-cytidine-tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CTP:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004112">
        <property type="term" value="F:cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016437">
        <property type="term" value="F:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01261">
        <property type="entry name" value="CCA_bact_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01262">
        <property type="entry name" value="CCA_bact_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012006">
        <property type="entry name" value="CCA_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000813">
        <property type="entry name" value="CCA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0533">Nickel</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0692">RNA repair</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000140054" description="Multifunctional CCA protein">
        <location>
            <begin position="1"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="228"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01175"/>
        </source>
    </evidence>
    <sequence length="413" mass="46361" checksum="FFD462F4C9B84F1E" modified="2008-04-29" version="1">MKFYLVGGAVRDNLLKLPIKDRDYMVVGAAPEQMFELGYKQVGKDFPVFLHPKTQQEYALARTERKTGSGYGGFSCDASPDVTLEEDLLRRDLTINAIAQDDKGELFDPYGGIKDIESKMLRHVSDAFVEDPLRVLRVARFAARFHHLGFTVADETLALMTKISQSGELEALTSERVFLELDKALSTQNPQIFIEVLNQCQALEILFPEIHALFGVPQPEKWHPEIDTGIHTLMVLAQAAKLSDENSVRFAALVHDLGKALSPKATLPKHHGHGQSGLALIKVLCARAKVPNEYRDLALLVSDQHQNVHNIRELRPETLIKIFDKADLWRKPDRLEQLATACEADSKGRLGLENSPYPQADYLRESFQVANSVAVKPIIEAGFKGAEIKEQLKLKRIEIVTEFKRNFNESAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHG3</accession>
    <name>B1KHG3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Aspartate ammonia-lyase</fullName>
            <shortName evidence="5">Aspartase</shortName>
            <ecNumber evidence="3 5">4.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1178</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-aspartate = fumarate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16601"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="4.3.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.1" evidence="3 5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323817.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1178"/>
    <dbReference type="EnsemblBacteria" id="ACA85471">
        <property type="protein sequence ID" value="ACA85471"/>
        <property type="gene ID" value="Swoo_1178"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1178"/>
    <dbReference type="eggNOG" id="COG1027">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021594_4_1_6"/>
    <dbReference type="OMA" id="EICENYV"/>
    <dbReference type="OrthoDB" id="734949at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008797">
        <property type="term" value="F:aspartate ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006531">
        <property type="term" value="P:aspartate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004708">
        <property type="entry name" value="ApsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00839">
        <property type="entry name" value="aspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="22"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="7">
        <location>
            <begin position="418"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="485" mass="52766" checksum="4115154845D49354" modified="2008-04-29" version="1">MTVMYANLSEETRLETDLLGDKSIPKEAFYGIHTLRAMENFNISSEKIGDCPEFVRGMVKTKKAAALANGELGTISQDIAAAIVRACDTLLAGERFYDQFPIDAFQGGAGTSVNMNTNEVIANIALTQMGHEKGSYQHINPNDHVNKSQSTNDAYPTGFRVALFERTESVLAALTLLIDTFMAKSAEFDDVLKMGRTQLQDAVPMTLGQEFRAFGVTLKEELKSIQRCQELLLEVNLGATAIGTGLNTPQGYSQLAIEKLAEITGHAFVPAEDLVEATSDCGAYVMLSSALKRFAIKLSKICNDLRLLSSGPRCGFNEINLPQMQAGSSIMPAKVNPVIPEVVNQVAFKVCGNDLTITMAAEAGQLQLNVMEPVIGQSLFESLSLLENACFTLKDKCIKGITANRQICQDFVLNSIGIITYLNPFIGHHEGDIVGKICAETGQSVREVVLARGLLSEEQLDEIFSIENLMNPQYKAQRFATAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHG4</accession>
    <name>B1KHG4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SNARE associated Golgi protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DedA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323818.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1179"/>
    <dbReference type="EnsemblBacteria" id="ACA85472">
        <property type="protein sequence ID" value="ACA85472"/>
        <property type="gene ID" value="Swoo_1179"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1179"/>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044208_6_2_6"/>
    <dbReference type="OMA" id="SNARFQF"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="PTHR30353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="233" mass="25722" checksum="CCF402D4A099ECC4" modified="2008-04-29" version="1">MLDSFISVLTALWQQDFALLQSPGSAAMIYLCIFSLIWLESALLPAAPMPCDSVVILSGSLAAAGIISLPLTFTILLVAAATGSWVAFLQGRWLHKLPKIQKWIDAVPEHRMNTVDKLLNQHGLLALFTARFIPVVRPLLPLMMGLHIKKVTHFHYFAWLSAGIWCALLIGFGYSLSYLPEKIAKVVTMGLMIAPVLTLAIAIVSFLTGYLLKKRRAVKTLKPLTQLDDRSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH9</accession>
    <name>B1KHH9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiazole biosynthesis protein ThiH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2587</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325204.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2587"/>
    <dbReference type="EnsemblBacteria" id="ACA86864">
        <property type="protein sequence ID" value="ACA86864"/>
        <property type="gene ID" value="Swoo_2587"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2587"/>
    <dbReference type="eggNOG" id="COG0502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046249_1_0_6"/>
    <dbReference type="OMA" id="LICAYRL"/>
    <dbReference type="OrthoDB" id="419725at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012726">
        <property type="entry name" value="ThiH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034428">
        <property type="entry name" value="ThiH/NoCL/HydG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43583">
        <property type="entry name" value="PTHR43583"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43583:SF1">
        <property type="entry name" value="PTHR43583:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00301">
        <property type="entry name" value="2-iminoacetate_synthase_(ThiH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02351">
        <property type="entry name" value="thiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="70"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="369" mass="41615" checksum="299A4A6C9C662479" modified="2008-04-29" version="1">MSFLSYLQGLSREKLSLKLYSCTGKDVEQALQHPEGSLESLLALLSPAAEPYLEQMAQTSARLTRQRFGANIGMYLPLYLSNLCANECDYCGFSMSNRIKRKTLSLDELNAEMRVVKAMDYDSILLVSGEHETKVGIDYFSSVLPSVKSQFSYVAMEVQPLKEAEYSQLAGLGLDAVMIYQETYNPQTYAEHHTRGNKQNFEYRLETPERVARAGVDKIGLGVLLGLDDWRLDALLLGHHLTYLESHFWRSRYSVSLPRLRPCTGGISPKVELTDRGLVQLICAFRLFNHQLEISLSTRESAELRNNLFGLGVTQLSAGSSTQPGGYLLPDTQLDQFEISDERTPVEVCVAMRDRGFNPVWKDWESAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ3</accession>
    <name>B1KHQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2662</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325278.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2662"/>
    <dbReference type="EnsemblBacteria" id="ACA86938">
        <property type="protein sequence ID" value="ACA86938"/>
        <property type="gene ID" value="Swoo_2662"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2662"/>
    <dbReference type="eggNOG" id="COG4206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008654_0_0_6"/>
    <dbReference type="OMA" id="NNPFQPD"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766618" evidence="5">
        <location>
            <begin position="33"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="55"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="270"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="781" mass="85592" checksum="76EBB7F38BB5922C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHU2</accession>
    <name>B1KHU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome c1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4164</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326749.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4164"/>
    <dbReference type="EnsemblBacteria" id="ACA88420">
        <property type="protein sequence ID" value="ACA88420"/>
        <property type="gene ID" value="Swoo_4164"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4164"/>
    <dbReference type="eggNOG" id="COG2857">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078597_0_0_6"/>
    <dbReference type="OMA" id="MPHVLWE"/>
    <dbReference type="OrthoDB" id="1426747at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="PTHR10266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764501" evidence="8">
        <location>
            <begin position="19"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="37"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="233" mass="26282" checksum="73B09740CC81E9B2" modified="2008-04-29" version="1" precursor="true">MKKLIIALVTLIPSLAFAAGGSHVPLESANIDLHDKESLQRGLDSFQHYCAGCHSTQYQRYGRVADDLGISVDDMRAKYIFDDSIKIGSLMENSIPSKDAAKWFGATPPDLTLVARVRGEDWIYSYLKGFYHDESRPFGVNNTVFPSVGMPHVMQELQGLPVKQEDGTIVSTGGKLNAEEYDQVVRDITGFLVYSGDPVKLERESLGWWVMGFLFIFFIIAYFLKKEYWKDVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI26</accession>
    <name>B1KI26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1211</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323850.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1211"/>
    <dbReference type="EnsemblBacteria" id="ACA85504">
        <property type="protein sequence ID" value="ACA85504"/>
        <property type="gene ID" value="Swoo_1211"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1211"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026846_0_1_6"/>
    <dbReference type="OMA" id="FTNRGKT"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013731">
        <property type="entry name" value="OapA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007340">
        <property type="entry name" value="Opacity-associatedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04225">
        <property type="entry name" value="OapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08525">
        <property type="entry name" value="OapA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OapA_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="OapA" evidence="6">
        <location>
            <begin position="120"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Csd3_N2" evidence="8">
        <location>
            <begin position="210"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="5">
        <location>
            <begin position="340"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="475" mass="52848" checksum="E4A219CFD08E25DB" modified="2008-04-29" version="1">MGKVITLLKLLPKMHQILLTVLVSVTLIILVLPADDAQASKNANSQLSGTIELNHLDESTTTTSEFNNQDKLKVPLAFRTPTPPSSASVIPKMNDEANLVKPEVSIAALRAEKVEQDHTETFKVKSGDTLAALFKRADLSARDVYEITLLPKAKKHLLKIMPGQEIMISKSSEGEFTQLKFHLDPVSTLVINKDDKGYEEKVVNKQIESRTKFASATISSNFWNAGVGAGLTPNQIMQLATIFGWDIDFALDLRKDDNFSIIFEEEFADGKFLRNGNILAAEFVNQGDRYTAVRYTDGNYYSEEGRSMRKAFLRSPVDFKYVSSSFNPKRLHPVTGQVRAHRGVDYVAAVGTPIKAAGKGRVIKSAYNKYNGNYVFIKHNDTYTTKYLHLKKRKVKQGQSVKQGQIIGTLGATGRVTGAHLHYEFIVNGTHRNPRTVKLPKSLPIANKEKPAFLALSKQIMAKLQQNKQVQLASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI59</accession>
    <name>B1KI59_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">recO</name>
        <name evidence="7" type="ordered locus">Swoo_1245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323883.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1245"/>
    <dbReference type="EnsemblBacteria" id="ACA85537">
        <property type="protein sequence ID" value="ACA85537"/>
        <property type="gene ID" value="Swoo_1245"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1245"/>
    <dbReference type="eggNOG" id="COG1381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066645_1_0_6"/>
    <dbReference type="OMA" id="YVLHSRA"/>
    <dbReference type="OrthoDB" id="1758685at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="6">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="228" mass="25451" checksum="706745C8CBBBC795" modified="2008-04-29" version="1">MLRGYVLHTRPFTDSSVLVNMLVDGQGRVDCVARLGSGKTSIKSILQPFQPLIFELSGRSNLKNLIRVESASPAVPISGEVSFAGFYLNELMVRCISVDHGAEEIFFVYHKTLMAMAAGFCQSQLRYFELSLLKEIGLMPTLNVDIAQDAIEADYYYRLLPDEGFVNALGPKTSHYSGEMLLSLESHTLQAEHFKQAKHLMRLLLAPCLGDKPLKSRALFKTKSQYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI84</accession>
    <name>B1KI84_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Bifunctional aspartokinase/homoserine dehydrogenase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="20">Aspartokinase</fullName>
                <ecNumber evidence="20">2.7.2.4</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="20">Homoserine dehydrogenase</fullName>
                <ecNumber evidence="20">1.1.1.3</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="22" type="ordered locus">Swoo_1270</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 20">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 20">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 20">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 20">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6 20">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 20">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 20">In the C-terminal section; belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10 20">In the N-terminal section; belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="20"/>
    <dbReference type="EC" id="1.1.1.3" evidence="20"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323908.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1270"/>
    <dbReference type="EnsemblBacteria" id="ACA85562">
        <property type="protein sequence ID" value="ACA85562"/>
        <property type="gene ID" value="Swoo_1270"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1270"/>
    <dbReference type="eggNOG" id="COG0460">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0527">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009116_7_1_6"/>
    <dbReference type="OMA" id="CNKIACS"/>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04257">
        <property type="entry name" value="AAK_AK-HSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041743">
        <property type="entry name" value="AK-HSDH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042199">
        <property type="entry name" value="AsparK_Bifunc_asparK/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011147">
        <property type="entry name" value="Bifunc_aspartokin/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070">
        <property type="entry name" value="PTHR43070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000727">
        <property type="entry name" value="ThrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="20" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15 20 22" id="KW-0418">Kinase</keyword>
    <keyword evidence="19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="17 20" id="KW-0521">NADP</keyword>
    <keyword evidence="14 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18 20 22" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="12 20 22" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="21">
        <location>
            <begin position="320"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00007952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00010046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRNR" id="PIRNR000727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ACA85562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="821" mass="89766" checksum="FD5CEFDA9F906E30" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI85</accession>
    <name>B1KI85_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Homoserine kinase</fullName>
            <shortName evidence="11">HK</shortName>
            <shortName evidence="11">HSK</shortName>
            <ecNumber evidence="4 11">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">thrB</name>
        <name evidence="14" type="ordered locus">Swoo_1271</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323909.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1271"/>
    <dbReference type="EnsemblBacteria" id="ACA85563">
        <property type="protein sequence ID" value="ACA85563"/>
        <property type="gene ID" value="Swoo_1271"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1271"/>
    <dbReference type="eggNOG" id="COG0083">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041243_1_1_6"/>
    <dbReference type="OMA" id="CANRIPH"/>
    <dbReference type="OrthoDB" id="610857at2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="12">
        <location>
            <begin position="86"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="13">
        <location>
            <begin position="230"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="33429" checksum="76F62C35F830C2C4" modified="2008-04-29" version="1">MSLTVYAPASMGNVGVGYDLLGAALAPIDGSLLGDKVSIAASTSGVQLKVEGHWADKLPPEPKENIVYQCALFFMEQLNKQDGVALTLEKNLPVGSGLGSSASSVVAALYALNEYFDRPYDKQALLRLMGEFEGKISGSVHYDNVAPCYLGGMQLMLDTQAKVCDSIPSFENWYWVVAYPGISLSTSKMRELLPDHYDKSVAIDFGRNLSAFVHASYQQDAELAISVLKDVMAEPYRASAIPGYELARDALDKLGMLSTGISGSGPTLFSVTDSLETAQAAQAWLDSNYVEQGLGFSHICKLDALGTRTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE2</accession>
    <name>B1KIE2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325330.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2717"/>
    <dbReference type="EnsemblBacteria" id="ACA86993">
        <property type="protein sequence ID" value="ACA86993"/>
        <property type="gene ID" value="Swoo_2717"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2717"/>
    <dbReference type="eggNOG" id="COG0722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_6"/>
    <dbReference type="OMA" id="PCLSWED"/>
    <dbReference type="OrthoDB" id="853329at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="44"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="38985" checksum="18D509F1509CB037" modified="2008-04-29" version="1">MTIKTDELRTTLLCKAISPAKLASEFPLTQDAADYLVQQRREVEAILKGDDQRLLVIIGPCSIHDTTAAIDYAKRLAALHQELKDDLCILMRVYFEKPRTTVGWKGLISDPDLDGSFNANKGLRLARQLLQEITELKLPIATEFLDMVNGQYIADLITWGAVGARTTESQIHREMASALSCPVGFKNGTDGNINIAIDAVRAAKEPHIFYSPDKDGAMAVYRTSGNPYGHIILRGGKQPNYHAEDINAAAEQLSDVGVSHRMVVDFSHGNSQKKHAQQLNVADSIMEQMRQGSTAIAGIMAESFIEEGNQKVVTGEPLVYGKSITDACLHWEDSETLLRALAKASRDRINLLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIX1</accession>
    <name>B1KIX1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="7">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="7">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1327</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323965.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1327"/>
    <dbReference type="EnsemblBacteria" id="ACA85619">
        <property type="protein sequence ID" value="ACA85619"/>
        <property type="gene ID" value="Swoo_1327"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1327"/>
    <dbReference type="eggNOG" id="COG0127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082080_0_3_6"/>
    <dbReference type="OMA" id="DCFADDT"/>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="153"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="200" mass="21826" checksum="AC713B37CA923F88" modified="2008-04-29" version="1">MDKFVLASGNKGKLKEFSEIFSEYGVEVFPQSQFNVAEVPETGTTFVENAIIKARHAAQVTGMAAIADDSGLEVDLLEGAPGIYSARYAGEGAGETDNYIKLLDALKDKPQARTARFQCILVYMRHAKDPTPIICQAAWEGKISFEAKGDNGHGYDPIFIPNEHSCSAAELSSEEKNRLSHRGKAMTLLIDAMRRQGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIZ3</accession>
    <name>B1KIZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alkaline phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1349</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323987.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1349"/>
    <dbReference type="EnsemblBacteria" id="ACA85641">
        <property type="protein sequence ID" value="ACA85641"/>
        <property type="gene ID" value="Swoo_1349"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1349"/>
    <dbReference type="eggNOG" id="COG1785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008539_4_1_6"/>
    <dbReference type="OMA" id="RIMSKGM"/>
    <dbReference type="OrthoDB" id="585847at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764933" evidence="3">
        <location>
            <begin position="21"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="543" mass="56984" checksum="50F31E8B98F329F7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ11</accession>
    <name>B1KJ11_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325367.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87031">
        <property type="protein sequence ID" value="ACA87031"/>
        <property type="gene ID" value="Swoo_2755"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2755"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127592_2_0_6"/>
    <dbReference type="OMA" id="GGICHKR"/>
    <dbReference type="OrthoDB" id="1864858at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="10"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="13995" checksum="528A4715EBBEBCB0" modified="2008-04-29" version="1">MQSPYSTPGALGWHELTSNSCEDAFGFYGKVFGWTFKTMQMSHGPYHIIENEGVGIGGIAPNPCPQQESHWTGYITVDDVDEVAIKAKSLGGELLYGPEDIPEVGRLCWIKDPQGAIIAAITYEKTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD0</accession>
    <name>B1KJD0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326928.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88602">
        <property type="protein sequence ID" value="ACA88602"/>
        <property type="gene ID" value="Swoo_4349"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4349"/>
    <dbReference type="eggNOG" id="ENOG5031IF1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160028_0_0_6"/>
    <dbReference type="OMA" id="EFMELTC"/>
    <dbReference type="OrthoDB" id="2076066at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764564" evidence="1">
        <location>
            <begin position="33"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="104" mass="11851" checksum="BB2FA689337C51AA" modified="2008-04-29" version="1" precursor="true">MSHSISKTKIHFSGKFAIIAALLVGFAFTNQASADAFTQTQQAAVDQHFDILARQQDKSDNKILNNQQQNFDDELEMAEDKFMTQICDEHGRVYDNKSQTCYEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJP6</accession>
    <name>B1KJP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324065.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1427"/>
    <dbReference type="EnsemblBacteria" id="ACA85719">
        <property type="protein sequence ID" value="ACA85719"/>
        <property type="gene ID" value="Swoo_1427"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1427"/>
    <dbReference type="eggNOG" id="ENOG50303H9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145285_0_0_6"/>
    <dbReference type="OMA" id="WYRFFGA"/>
    <dbReference type="OrthoDB" id="1980707at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15107" checksum="6B9A91626459C885" modified="2008-04-29" version="1">MNIFLLLAGTLSGIAGLLHLGCIYFGGPWYRFFGAGEQMAQLAEQGSLRPTLITLGITSVLAIWSLYAFSAAGVIGRLPFIKTVLVVITSIYLLRGVAGFLLINNPMGRSAEFWIWSSIICLALGLMHLFGLKQQWASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK07</accession>
    <name>B1KK07_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325530.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2921"/>
    <dbReference type="EnsemblBacteria" id="ACA87194">
        <property type="protein sequence ID" value="ACA87194"/>
        <property type="gene ID" value="Swoo_2921"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2921"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="EWLPSIN"/>
    <dbReference type="OrthoDB" id="76759at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767135" evidence="6">
        <location>
            <begin position="31"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="67"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="399"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="859" mass="95472" checksum="C50F7EB59B338B7F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK08</accession>
    <name>B1KK08_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein TonB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_2922</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell inner membrane</location>
            <topology evidence="1 9">Single-pass membrane protein</topology>
            <orientation evidence="1 9">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325531.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2922"/>
    <dbReference type="EnsemblBacteria" id="ACA87195">
        <property type="protein sequence ID" value="ACA87195"/>
        <property type="gene ID" value="Swoo_2922"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2922"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_597027_0_0_6"/>
    <dbReference type="OMA" id="AWIMATH"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031992">
        <property type="term" value="F:energy transducer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003538">
        <property type="entry name" value="TonB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01374">
        <property type="entry name" value="TONBPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764979" description="Protein TonB" evidence="10">
        <location>
            <begin position="23"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="151"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="458" mass="53073" checksum="B539E3470BDDBDEE" modified="2008-04-29" version="1" precursor="true">MMKFYLSIIIFLSLVFSSNSRADLLSATLEYNKGNYLSSYQEFHRLAQLGNRDAIFNIGVMYLHGQGVEKNLTSAHSWFLLAADFGVDEARSAARLIEVEVDDQEGLDRDYQLLNQKFSYTIFSRDLQPIFSPIQYNDDKQPKRTYTLDAKYPQEAYEQGQEGWVWLDFDIDQSGAVKDVEILDSFPDNTFNRAIYNAVRRWRYEPYMVNGKAQIYRNRSLIYHFTTFKGKRYQESFASQKREYQKKINQLIDSAEQGNAIVQYYIANWMIADEHNATRLLKFHWSDDNAGSQLLLSSASNGYSNSQYRLGSSLLRGEYTQASRQKGLNWILLAAQGGFIHAQYRLARELLDRQHVEFDQEKSQRWMKAAADNGHFRAIRDLVNQGIDAKDFTSSLHYLKLGLKQDDSHPDLLLAQAKIFKHQGQHALAVKKAQQALKEAKDRGWYTQEISQYLQSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKB0</accession>
    <name>B1KKB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324096.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1462"/>
    <dbReference type="EnsemblBacteria" id="ACA85750">
        <property type="protein sequence ID" value="ACA85750"/>
        <property type="gene ID" value="Swoo_1462"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1462"/>
    <dbReference type="eggNOG" id="ENOG50345JN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2131837_0_0_6"/>
    <dbReference type="OMA" id="CRINNIQ"/>
    <dbReference type="OrthoDB" id="2018701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767426" evidence="1">
        <location>
            <begin position="25"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12099" checksum="F84597B2457484DB" modified="2008-04-29" version="1" precursor="true">MKTPLLTLVFLLMFNFSFVTQATAGVTWASGKITSLMASATNPAIRLTGNISPDRCSGGTYGWLYFAGTAEEKNRIYATALAMSLSGKTVTVYTNGDDTTCRINNIQITSGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD6</accession>
    <name>B1KKD6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324122.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1488"/>
    <dbReference type="EnsemblBacteria" id="ACA85776">
        <property type="protein sequence ID" value="ACA85776"/>
        <property type="gene ID" value="Swoo_1488"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1488"/>
    <dbReference type="eggNOG" id="ENOG5031I5Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165522_0_0_6"/>
    <dbReference type="OMA" id="CKLYAIE"/>
    <dbReference type="OrthoDB" id="2029895at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764608" evidence="1">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12707" checksum="4FF78E114E1DA80D" modified="2008-04-29" version="1" precursor="true">MKSITLLTLLFLFSLFGVSNSYAAIESTGQTSIKRLISYNQYGGGDVVFTVNEPSSNCDGYWIAKSDAGFDANLSMILAAYHSKSKVRIYGHDEQKWNGSTSFWCKLYAIEHTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKK5</accession>
    <name>B1KKK5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325558.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2949"/>
    <dbReference type="EnsemblBacteria" id="ACA87222">
        <property type="protein sequence ID" value="ACA87222"/>
        <property type="gene ID" value="Swoo_2949"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2949"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013917_0_1_6"/>
    <dbReference type="OMA" id="AVDCGPQ"/>
    <dbReference type="OrthoDB" id="337328at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012368">
        <property type="entry name" value="OxRdtase_Mopterin-bd_su_IorB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036389">
        <property type="entry name" value="IOR_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="209"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="749" mass="81227" checksum="4209E92FBF8332FB" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL5</accession>
    <name>B1KKL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325568.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2959"/>
    <dbReference type="EnsemblBacteria" id="ACA87232">
        <property type="protein sequence ID" value="ACA87232"/>
        <property type="gene ID" value="Swoo_2959"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2959"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013852_0_0_6"/>
    <dbReference type="OMA" id="TQQWQEE"/>
    <dbReference type="OrthoDB" id="291634at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="169"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="515"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="937" mass="107008" checksum="5C2F27546ED3A9F0" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKQ4</accession>
    <name>B1KKQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325607.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3000"/>
    <dbReference type="EnsemblBacteria" id="ACA87271">
        <property type="protein sequence ID" value="ACA87271"/>
        <property type="gene ID" value="Swoo_3000"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3000"/>
    <dbReference type="eggNOG" id="ENOG5032S98">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099361_0_0_6"/>
    <dbReference type="OMA" id="RAGENWL"/>
    <dbReference type="OrthoDB" id="1574258at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027056">
        <property type="entry name" value="Gluconate_2DH_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13618">
        <property type="entry name" value="Gluconate_2-dh3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="211" mass="23240" checksum="1581F451E2335565" modified="2008-04-29" version="1">MLKTAKAKLERGSNKPTFVTAYESGLNRRAFLRQTGAAAVLLGLIGAKPTILQAQESESRVGGGTEFTPLAVTVVKAVQLQLFPDDGDGPSSEQLNSFQYLRWALEDPENQADGDKEFILQGVGWLEELAKSTHGASFIKLSTKEQDTVLKQIAKSRAGENWLSLLLYYLLESLTLDPIYGGNPDGIGWQWLEHQPGFPRPVKGKTYLDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKQ8</accession>
    <name>B1KKQ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DSBA oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3004</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3004"/>
    <dbReference type="EnsemblBacteria" id="ACA87275">
        <property type="protein sequence ID" value="ACA87275"/>
        <property type="gene ID" value="Swoo_3004"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3004"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_47_4_6"/>
    <dbReference type="OMA" id="CKKIEPS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041205">
        <property type="entry name" value="ScsC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18312">
        <property type="entry name" value="ScsC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="75"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="29286" checksum="C4EEA0FE1C37771E" modified="2008-04-29" version="1" precursor="true">MLFSNKTVSKYKIKMISAIATALLISLVQISWVNLAHAELESLTAQQQADVKAIIKDALINDPELLKEAIIALQTREQQGADAARQSALNSHKQALFETKTDPWKGASDPEITMVYFTDFNCPYCKKLEPSLDKLVKEFPQLKIIIKMVPLQGEASEEAVALAQTVWLNEPSKYLKLKEVLMSSPRKLDSESIAKVAKLTGTEIWLNNTDKTVNQQVKDNVNLMMALGLRGTPAMIFGDKVIPGLVTYEVLKEQLEEAIEAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW1</accession>
    <name>B1KKW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4516</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88767">
        <property type="protein sequence ID" value="ACA88767"/>
        <property type="gene ID" value="Swoo_4516"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4516"/>
    <dbReference type="eggNOG" id="COG1032">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044464_1_0_6"/>
    <dbReference type="OMA" id="RCNHASN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="9"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="293" mass="32851" checksum="28C326258E7803C0" modified="2008-04-29" version="1">MRYIEPVFRPPSEWKSLILQVTNGCSWNKCTFCDMYTAPQKRFRAQKLDKILEDIKVVANTGQNITRVFLADGDAMSLPFERLEAICLLIQEHLPSVTRISSYCLPRNLKNKTSEQLTRLRELGLSLLYIGCESGDDEVLNRIEKGETYASSLTALLKIKAAGIKSSVMILNGLGGSGLSEQHAINSARLMNAAQPEYLSTLVVTLPLGTERMDSAFDGHFSLPNQAELFKEMHTLLGHLELERTIFRSDHASNYLVLKGTLGKDKPRLLAEVKQAISNPLQTSLRKEWQRGL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL12</accession>
    <name>RNPH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease PH</fullName>
            <shortName evidence="1">RNase PH</shortName>
            <ecNumber evidence="1">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rph</name>
        <name type="ordered locus">Swoo_4568</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327143.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL12"/>
    <dbReference type="SMR" id="B1KL12"/>
    <dbReference type="STRING" id="392500.Swoo_4568"/>
    <dbReference type="EnsemblBacteria" id="ACA88818">
        <property type="protein sequence ID" value="ACA88818"/>
        <property type="gene ID" value="Swoo_4568"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4568"/>
    <dbReference type="eggNOG" id="COG0689">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050858_0_0_6"/>
    <dbReference type="OMA" id="KGKGQGW"/>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000129374" description="Ribonuclease PH">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="124"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <sequence length="237" mass="25743" checksum="C750AD9E34761E79" modified="2008-04-29" version="1">MRPNDRTPAQSRPVTITRQFTAHAEGSVLVEFGETKVLCTASFTEGVPRFLKGKGQGWVTAEYGMLPRSTHSRMDREAARGKQSGRTQEIQRLIGRSLRAAVDMKALGENTIVIDCDVIQADGGTRTAAITGACVALVDALNWARGKGILKNNPLKFLIAAVSVGIYKGEPICDLEYIEDSEAETDMNVVMTETGKMIEIQGTAEGEPFSHEELLSLLELAKHGIREIVDVQKAALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL47</accession>
    <name>B1KL47_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein, family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322737.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0087"/>
    <dbReference type="EnsemblBacteria" id="ACA84388">
        <property type="protein sequence ID" value="ACA84388"/>
        <property type="gene ID" value="Swoo_0087"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0087"/>
    <dbReference type="eggNOG" id="COG2998">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061511_0_0_6"/>
    <dbReference type="OMA" id="LADRGTW"/>
    <dbReference type="OrthoDB" id="1567509at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767172" evidence="1">
        <location>
            <begin position="25"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="29"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="29035" checksum="DECC02615C83E591" modified="2008-04-29" version="1" precursor="true">MLNLKSIFSLALAATLVTAMPATAEEIIKLATTTSTENSGLLKNLLPKFEAETGYKVQVIATGTGKALKLARQGDVDLVMTHAPAAEAKFVNEGFGILPRGIMENDFVILGPKNDPAKIRGSKTAEEAFAKIAKSGATFISRGDNSGTNMKELIIWKNADIALTFNGYKAVGQGMGKTLLMASELQGYTLSDRGTFVAYKAKLDLAIDYDGGKALANPYQIVLINPEKYPELNHKGARAFSDWLIGAEAQGMINSYKVQGEQLFKATYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL67</accession>
    <name>B1KL67_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YheO domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322757.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0107"/>
    <dbReference type="EnsemblBacteria" id="ACA84408">
        <property type="protein sequence ID" value="ACA84408"/>
        <property type="gene ID" value="Swoo_0107"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0107"/>
    <dbReference type="eggNOG" id="COG2964">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080179_3_0_6"/>
    <dbReference type="OMA" id="KLNWDGR"/>
    <dbReference type="OrthoDB" id="1474443at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039446">
        <property type="entry name" value="DauR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039445">
        <property type="entry name" value="DauR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013559">
        <property type="entry name" value="YheO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35568">
        <property type="entry name" value="PTHR35568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13309">
        <property type="entry name" value="HTH_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08348">
        <property type="entry name" value="PAS_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS_6" evidence="1">
        <location>
            <begin position="21"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_22" evidence="2">
        <location>
            <begin position="166"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25246" checksum="076CDB47031D2686" modified="2008-04-29" version="1">MIKTTEHTYKTEFTSRDRELLEGYFRLADSMADLIGPHCEVVIHSLENFEQSVVKIVNGHHTGRKEGSPITDLGLKMLRLYEQTGEVTPKSYFSNNKGGEMLKSSTCILAGEDGKPIGMFCVNMNLSHPFPEIIKTLMPDTSQHQSFDMTENFSASAGDVVEQALTHAISEVDADTSVNLKGRNKAITKVLFDNGIFELKEATNIVANHLSITKHAVYKYIREFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL75</accession>
    <name>B1KL75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysyl endopeptidase</fullName>
            <ecNumber evidence="3">3.4.21.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.50" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322765.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0115"/>
    <dbReference type="EnsemblBacteria" id="ACA84416">
        <property type="protein sequence ID" value="ACA84416"/>
        <property type="gene ID" value="Swoo_0115"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0115"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_343844_0_0_6"/>
    <dbReference type="OMA" id="DATEGQH"/>
    <dbReference type="OrthoDB" id="1162936at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764630" evidence="1">
        <location>
            <begin position="24"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="466"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="659"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="823" mass="88119" checksum="46554326018C1D4D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL96</accession>
    <name>B1KL96_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase S45 penicillin amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0136</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322786.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0136"/>
    <dbReference type="MEROPS" id="S45.004"/>
    <dbReference type="EnsemblBacteria" id="ACA84437">
        <property type="protein sequence ID" value="ACA84437"/>
        <property type="gene ID" value="Swoo_0136"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0136"/>
    <dbReference type="eggNOG" id="COG2366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017615_0_0_6"/>
    <dbReference type="OMA" id="QGIPWVN"/>
    <dbReference type="OrthoDB" id="186419at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767176" evidence="5">
        <location>
            <begin position="23"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="793" mass="86392" checksum="01B19280EDB17EE3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI7</accession>
    <name>B1KLI7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Flagellar motor switch protein FliN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1626</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324258.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1626"/>
    <dbReference type="EnsemblBacteria" id="ACA85912">
        <property type="protein sequence ID" value="ACA85912"/>
        <property type="gene ID" value="Swoo_1626"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1626"/>
    <dbReference type="eggNOG" id="COG1886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097058_1_1_6"/>
    <dbReference type="OMA" id="THNDIDM"/>
    <dbReference type="OrthoDB" id="1875967at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012826">
        <property type="entry name" value="FliN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02480">
        <property type="entry name" value="fliN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5 8" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="6 8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="9">
        <location>
            <begin position="49"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14085" checksum="6639535A6E70761E" modified="2008-04-29" version="1">MSTEDTGDDWANAMAEQALEEAEAVELDELTDNTTAADLSEEDVAKLDAIMDIPVTISMEVGRSFINIRNLLQLNQGSVVELDRVAGEPLDVMVNGTLIAHGEVVVVNDKFGIRLTDVISQTERIKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK2</accession>
    <name>B1KLK2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobyrinic acid ac-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324273.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1641"/>
    <dbReference type="EnsemblBacteria" id="ACA85927">
        <property type="protein sequence ID" value="ACA85927"/>
        <property type="gene ID" value="Swoo_1641"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1641"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037612_1_2_6"/>
    <dbReference type="OMA" id="RVWAVAN"/>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="28709" checksum="EAE183E474B8A4A3" modified="2008-04-29" version="1">MKIWTIANQKGGVGKTTTVASLAGTLAKRGLKVLMIDTDPHASLGYYLGIDSEDVNSSLYDLFLEHKQLTTELVKEHIVSTQVEGIDLLPSTMALATLDRSLGHQGGMGLILKKILLLVEESYDIALIDCPPVLGVLMVNALAASQHIIVPVQTEFLAIKGLDRMLKTMILMGRSKNIKYGYTIVPTMYDRRTKASSAALQQLSQDYGEQLWMDVIPVDTKFRDASLAHLPASHFAATSRGVKAYARLLDYLLAGASPHVKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLY0</accession>
    <name>B1KLY0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabA/FabZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327185.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4610"/>
    <dbReference type="EnsemblBacteria" id="ACA88860">
        <property type="protein sequence ID" value="ACA88860"/>
        <property type="gene ID" value="Swoo_4610"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4610"/>
    <dbReference type="eggNOG" id="COG4706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116661_0_0_6"/>
    <dbReference type="OMA" id="GMGVFEC"/>
    <dbReference type="OrthoDB" id="1960828at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01289">
        <property type="entry name" value="FabA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016776">
        <property type="entry name" value="Hydroxyacyl-ACP_deHydtase_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020565">
        <property type="entry name" value="3Ho_Ac_ACP_DH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="167" mass="18652" checksum="7D45739B72C67E72" modified="2008-04-29" version="1">MSQEIELQTFELPTPLSQLSVAEVVPHRAPMILIDELVAHEADSLITQTNITTDSPYFDETLNAVPNYVGIEYMAQSVAALAGVEAKKRGDIIRVGFLLGSRKLKMHIPNYQLGESYRTHVSRLYQEESGLAVFDCQIFHHDTLVAEANVNVFQPQDTQTYISESQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLZ4</accession>
    <name>B1KLZ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327199.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4624"/>
    <dbReference type="EnsemblBacteria" id="ACA88874">
        <property type="protein sequence ID" value="ACA88874"/>
        <property type="gene ID" value="Swoo_4624"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4624"/>
    <dbReference type="eggNOG" id="ENOG5033T3J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1128453_0_0_6"/>
    <dbReference type="OrthoDB" id="1448351at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="28916" checksum="1B56E2883CDE7626" modified="2008-04-29" version="1" precursor="true">MKFKLFSILLILAIFFGVIISSDHKQKPNFYKVDIQERAQIEKIYALMNEQKYDLALPLIEISLPKLLAKQSNDGSMIAWLYDMKAHVMASRYHFHYAIEAITKANQHKSDLRYRKLREEWLEEIDAMQGERQLRTSYISGRNAGLSQSLTNDIHIAYIYIDDNRSSKWSGKQRIKNQVSVDKVLDWYKQQASHYAIDELDFKVRYFVVNSPKGVGKEWLRDPAAFRQILNNLFKRLSFRGIGEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM20</accession>
    <name>B1KM20_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327224.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4650"/>
    <dbReference type="EnsemblBacteria" id="ACA88900">
        <property type="protein sequence ID" value="ACA88900"/>
        <property type="gene ID" value="Swoo_4650"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4650"/>
    <dbReference type="eggNOG" id="COG3852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_39_6"/>
    <dbReference type="OMA" id="HGGRIDC"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="133"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="348" mass="38584" checksum="287DBCEE89E9707D" modified="2008-04-29" version="1">MDTKHLLNNLVTAVIVIDADLKLCYANAAAEQLLGVGIHRLTEHFLADNFRLIGVSNELLTESIKENQGLTVNTASLITFDNQHHTVDITLSPLEQEQGLALLELRQVDQQLRIHQQLTLDAQQQAAQYLVRNLAHEIKNPLGGLRGAAQLLSRELHDPQLNEFTDLIIEQADRLRNLVDRLLGPQKPTKHSLHNIHEVIQKVLKLVSMALPENIDLEQDYDPSIPDIQMDPEQLQQAILNIVQNAVQALECGGGNILIKTRTQHQVTIGTERHKLVLALSIIDNGPGVKPELLDTLFYPMVTGRDNGSGLGLSISHNFARLHGGRIDCQSTSAGTEFTILLPIENNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM86</accession>
    <name>B1KM86_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322848.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0198"/>
    <dbReference type="EnsemblBacteria" id="ACA84499">
        <property type="protein sequence ID" value="ACA84499"/>
        <property type="gene ID" value="Swoo_0198"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0198"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_225140_0_0_6"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003284">
        <property type="entry name" value="Sal_SpvB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03534">
        <property type="entry name" value="SpvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766832" evidence="5">
        <location>
            <begin position="25"/>
            <end position="3333"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="905"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="994"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="1083"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3130"/>
            <end position="3159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="3135"/>
            <end position="3159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="3333" mass="359681" checksum="5F4A7C2438FBF081" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMD6</accession>
    <name>B1KMD6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1648</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324280.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1648"/>
    <dbReference type="EnsemblBacteria" id="ACA85934">
        <property type="protein sequence ID" value="ACA85934"/>
        <property type="gene ID" value="Swoo_1648"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1648"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064295_0_0_6"/>
    <dbReference type="OMA" id="HWHLEYL"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="367" mass="41097" checksum="4E04A10EAA21CABC" modified="2008-04-29" version="1">MALKELVVLLVEDDPVFRRIVASFLDSRGATVLEADDGEQGLDRFKQYAVDIVLADLSMPIMGGLVMLKKMSEINPSVPSIVISGNQVMADVVEALRIGASDYLVKPVADLFLIESAIKQCLDERHMKDVQLEDMEELSYQELQDNLVLLEQNAEAAKSVQQQLFPPSQINYPCAKIDYSLFKSDEVSAYFIDTVNVGERHLVMYMAHFTPQDNRAAFGSVLLKSFVNQKLKLFRDGSTQAIIEPYNMLCYLNERMTKSGLDIFIDIVYVVVELTQFRASIAQAGHGLRCYLRNSEGLMPLALPDSLQLGILDWGQPSSHFRTLMPGESFCISSSAPEHKQMLLKDHFCGLTYDTQTPNGGYVQLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMF6</accession>
    <name>B1KMF6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324300.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1668"/>
    <dbReference type="EnsemblBacteria" id="ACA85954">
        <property type="protein sequence ID" value="ACA85954"/>
        <property type="gene ID" value="Swoo_1668"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1668"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_6"/>
    <dbReference type="OMA" id="ITGGRNW"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="26888" checksum="BB8B72B514772BAB" modified="2008-04-29" version="1">MSNELAGKTILVTGASSGLGKAIAIYFSTVGARVVLTGRNEERLHETLKDMSGSNHLYFIADLAKVESTQAMMDTVFANVGALDSVIHCAGIQKTLPLQALKEHHFDDIFNTNVKSAQFIAKFLRKKGRYNSQGTSLVLLSSVAAVCGEPAISSYSASKAALLGLSKSLAIELARQNIRVNCIAPGHVGTEMAIEFSKQLTAEQRENILLKHPLGLGKPEYIAQAAEFLASDKSCWITGTTIFVDGGYSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMM5</accession>
    <name>B1KMM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lytic transglycosylase catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325739.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3132"/>
    <dbReference type="CAZy" id="GH23">
        <property type="family name" value="Glycoside Hydrolase Family 23"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87403">
        <property type="protein sequence ID" value="ACA87403"/>
        <property type="gene ID" value="Swoo_3132"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3132"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_794306_0_0_6"/>
    <dbReference type="OMA" id="AIMQIES"/>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024570">
        <property type="entry name" value="Murein_transglycosylaseC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11873">
        <property type="entry name" value="Mltc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767213" evidence="2">
        <location>
            <begin position="21"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Mltc_N" evidence="4">
        <location>
            <begin position="74"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="3">
        <location>
            <begin position="187"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="39835" checksum="BD9987E359225C0C" modified="2008-04-29" version="1" precursor="true">MKPTLLVCFTLLLSPLICHAVQLSDYDADVAALLLEYQGDGDVAALLRKYQGTTASSAMARPSVLTIKEQGDASTYVDFERGIILIETPDKALLKEAIVQVLLTQIDPKLIDAKTAQDFGLINKGKKPFFWGQIHDHQGEAIEYSWRAERFADYLIKHKLSQDSRVRVAIHMVAEHTKIAGGKYIHYAQAASRRYGVSTELIMAIMETESSFNPMARSRSNALGLMQVKANTAGRDYFSLIKGYKHTPSSAYLYDPQKNIDLGTGYLQILSKRYLAGINHPKKLEYAMISSYNGGSGNLWKSLDPQANRTKAIARINKMSVSEFYWFLTNRHIRGETRNYLKKVSSKQKKYAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP7</accession>
    <name>B1KMP7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325761.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87425">
        <property type="protein sequence ID" value="ACA87425"/>
        <property type="gene ID" value="Swoo_3154"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3154"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155955_0_0_6"/>
    <dbReference type="OMA" id="MVDVFTF"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="13627" checksum="7752B89EE38D06E7" modified="2008-04-29" version="1">MITDDLQAYVDAWNEHDIDKIMSFMSKDCVFETGGGAEVYGTRHSGFEAVKARFISVLETMPDVSFNQAKHFVQADRGCSEWIFTATKPDGTKIELEGCDIFTFHKGKIKVKSSFMKHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMT1</accession>
    <name>B1KMT1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Leucyl aminopeptidase</fullName>
            <ecNumber evidence="7">3.4.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3188</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325795.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3188"/>
    <dbReference type="EnsemblBacteria" id="ACA87459">
        <property type="protein sequence ID" value="ACA87459"/>
        <property type="gene ID" value="Swoo_3188"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3188"/>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013734_2_1_6"/>
    <dbReference type="OMA" id="HFDIYGW"/>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="6">
        <location>
            <begin position="300"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="453" mass="49324" checksum="B8763137E15F7A2F" modified="2008-04-29" version="1">MTNLLISGASGTPLSILHTDSFDAWLTEQTQQTKNWLSTTQFSGKGMSLIPDANGELSQVIFVSSEPESYWVCGDLVNQLPAGQYQLKASEEQLKVAAFSWGLGAYKFDRYKKNEKTYPTLVINNQQIVEQAQKLVRSVSIVRDLVNTPAADMMPQHLGDTMEALATEFGAKVSQIVGDDLLKQNYPTIHMVGRASENLPRLIDLTWGDESAPQVTLVGKGVCFDSGGLDLKPGAGMRLMKKDMGGAAHVIGLAHQIMASNLPIRLRVLVPAVENAVSANAFRPGDVITTRKGITVEIDNTDAEGRLVLCDALAEANNDNPDLVIDFATLTGAMRIALGTELPGFFSNDDTLAAEMTVSGLKVEDPIWRMPLHKPYMELTGSDIADLANCGKTPFGGAITAALYLEAFVEKEISWAHFDVMAWNNRKLPGRPVGGEAFGIRAVFDYLETRFKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMW2</accession>
    <name>RL36_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmJ</name>
        <name type="ordered locus">Swoo_4669</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMW2"/>
    <dbReference type="SMR" id="B1KMW2"/>
    <dbReference type="STRING" id="392500.Swoo_4669"/>
    <dbReference type="EnsemblBacteria" id="ACA88919">
        <property type="protein sequence ID" value="ACA88919"/>
        <property type="gene ID" value="Swoo_4669"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4669"/>
    <dbReference type="eggNOG" id="COG0257">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135723_6_2_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="PTHR42888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000101070" description="50S ribosomal protein L36">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <sequence length="37" mass="4277" checksum="52F6D895DC00283D" modified="2008-04-29" version="1">MKVRASVKKICRNCKIIKRSGVVRVICVEPKHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN65</accession>
    <name>B1KN65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0261</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322911.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0261"/>
    <dbReference type="EnsemblBacteria" id="ACA84562">
        <property type="protein sequence ID" value="ACA84562"/>
        <property type="gene ID" value="Swoo_0261"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0261"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_6_1_6"/>
    <dbReference type="OMA" id="WAFPAPE"/>
    <dbReference type="OrthoDB" id="1077305at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766883" evidence="3">
        <location>
            <begin position="34"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="71"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="211"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="481" mass="52369" checksum="7F67B4DDFFCACFAD" modified="2008-04-29" version="1" precursor="true">MNTLTNLSNRSNKLMAAMALGSILMLSACSSTAPSKVVDTGSFNVPSYEQYVLDNGLTLYLMPQKEVPLITVNAVVRAGAVNDTTAGVASMTAKSLLLGSNGKSKSEIELMVDFLGASIDAGAGKEGSYLEADFMAKDSETILPLFQNLLLSPNFDRKEFEKLRQREIGGLSQAKESPRSVISRYFDKLIFGKHPYGNTSSGNRSSLAELEASQLRAFYKSYYQPSNTAITLVGDFDVAQMKANMEALFGQWKGSEPIVKAELKSAQPKLDKSQVLLVNKGDAVESTFLIGGKGIARDNPDYVGLQVINTILGGRFTSWLNDELRVNAGLTYGARSGFVAYSEGGVFKISTFTKTETTKETIDLALKTYARLWETGIDQETLDSAKAYVKGQFPPKYETSGQLAGLLSDMYLYGFDDSFINDFQSNVDGLTLAETQRLIGKYFPQKNLQFVLIGNGEKIKHIASEYGEVTQVDIEAVGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN87</accession>
    <name>B1KN87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0283</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322933.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0283"/>
    <dbReference type="EnsemblBacteria" id="ACA84584">
        <property type="protein sequence ID" value="ACA84584"/>
        <property type="gene ID" value="Swoo_0283"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0283"/>
    <dbReference type="eggNOG" id="COG0053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_3_0_6"/>
    <dbReference type="OMA" id="IEMHLIV"/>
    <dbReference type="OrthoDB" id="381612at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="213"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="31535" checksum="86CAF7E87A4A15C5" modified="2008-04-29" version="1">MTQTSQYDFWVKLASRAAVATALTLVIIKMAAWLYSGSASMLASLTDSFADGLASLVNFAAIRYAIVPADHDHRYGHGKAEPLAALAQSAFILGSAFLLLFHGGDRLINPAPINHAMLGVVVSIIAIVLTFALVMLQKKAVEATSSTVVEADALHYKSDLFLNAAVLLALVLAQYGWWWADGLFAILIALFIGQQALELGYRSIQSLLDRELDNDTRLKIVELAQEDPQVKGIHDLRTRESGKTTFIQCHLEIEGSLSLREAHAIADRTEARIRAAFDDAEVIIHQDPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE7</accession>
    <name>B1KNE7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sodium pump decarboxylase gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324370.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1739"/>
    <dbReference type="EnsemblBacteria" id="ACA86024">
        <property type="protein sequence ID" value="ACA86024"/>
        <property type="gene ID" value="Swoo_1739"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1739"/>
    <dbReference type="HOGENOM" id="CLU_2540727_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9385" checksum="ED2023DEBB3748B4" modified="2008-04-29" version="1">MDVYQAIFTALNIMFLGMFCVFTFLGILILAVNSVSYFYSVNYEAALDEPKATTNNNTEVITAIATAIFQYRKSRGIPHNKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNJ2</accession>
    <name>B1KNJ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TraR/DksA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324415.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1785"/>
    <dbReference type="EnsemblBacteria" id="ACA86069">
        <property type="protein sequence ID" value="ACA86069"/>
        <property type="gene ID" value="Swoo_1785"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1785"/>
    <dbReference type="eggNOG" id="COG1734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043144_5_1_6"/>
    <dbReference type="OMA" id="GVCSDCE"/>
    <dbReference type="OrthoDB" id="1932026at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="5">
        <location>
            <begin position="35"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="13783" checksum="C8E14567E0E37742" modified="2008-04-29" version="1">MSRSHIRHELSKLESCLRKEIGELANKHQIKLESKQSSLCEIIEVLTQAKLCDEPLFCRLTKLDAAFCQLDIGLYGLCADCENEIEPERLAWDMLEQRCAECAENYEHQHRQELRLNH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNK5</accession>
    <name>KAD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenylate kinase</fullName>
            <shortName evidence="1">AK</shortName>
            <ecNumber evidence="1">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">adk</name>
        <name type="ordered locus">Swoo_1798</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324428.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNK5"/>
    <dbReference type="SMR" id="B1KNK5"/>
    <dbReference type="STRING" id="392500.Swoo_1798"/>
    <dbReference type="EnsemblBacteria" id="ACA86082">
        <property type="protein sequence ID" value="ACA86082"/>
        <property type="gene ID" value="Swoo_1798"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1798"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032354_1_2_6"/>
    <dbReference type="OMA" id="FHNRMRV"/>
    <dbReference type="OrthoDB" id="1491686at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000100608" description="Adenylate kinase">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="1">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="132"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <sequence length="214" mass="23196" checksum="DD9F4A37B41031D9" modified="2008-04-29" version="1">MRIMLLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKAGTPLGLEAKKVMDAGQLVSDELIIGLVKERVAQADCEKGFLLDGFPRTIPQADAMADAGIAIDHVVEIDVPDEEIVKRMSGRRVHPGSGRVYHIVFNQPKVEGKDDVTGEDLAIRPDDEESTVRKRLDIYHEQTKPLVEYYGNVAANGQTKYSKFDGTQSVASVSEEIVVALS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU2</accession>
    <name>EFTS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor Ts</fullName>
            <shortName evidence="1">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tsf</name>
        <name type="ordered locus">Swoo_3280</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EF-Ts family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325886.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNU2"/>
    <dbReference type="SMR" id="B1KNU2"/>
    <dbReference type="STRING" id="392500.Swoo_3280"/>
    <dbReference type="EnsemblBacteria" id="ACA87550">
        <property type="protein sequence ID" value="ACA87550"/>
        <property type="gene ID" value="Swoo_3280"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3280"/>
    <dbReference type="eggNOG" id="COG0264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047155_0_2_6"/>
    <dbReference type="OMA" id="DAGMMDC"/>
    <dbReference type="OrthoDB" id="1405357at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000116790" description="Elongation factor Ts">
        <location>
            <begin position="1"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="1">
        <location>
            <begin position="79"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <sequence length="282" mass="30283" checksum="493A31CAC1AD1BDA" modified="2008-04-29" version="1">MAITAAQVKELRDRTGAGMMDCKKALTETAGDIELAIDNMRKSGAAKAAKKAGNIAAEGTILIKNGEGYAALLEVNCQTDFVAKDSNFLAFANEVLDVAAASKVTIEDLKAQFEETRVALVAKIGENINVRRVEYIDGANLAQYRHGERIGVVVTGEADEETLKHVAMHVAASKPEYVNPSDVPAEVVEKEKALQIEIAMNEGKPAEIAEKMVIGRMKKFTGEVSLTGQAYIMEPKKTVGEVLKEKGASVSNFIRLEVGEGIERKEEDFAAEVAAQIAATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX3</accession>
    <name>B1KNX3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3312</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325917.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3312"/>
    <dbReference type="EnsemblBacteria" id="ACA87581">
        <property type="protein sequence ID" value="ACA87581"/>
        <property type="gene ID" value="Swoo_3312"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3312"/>
    <dbReference type="eggNOG" id="COG1764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105860_0_0_6"/>
    <dbReference type="OMA" id="IWSPEHL"/>
    <dbReference type="OrthoDB" id="1984062at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="146" mass="15906" checksum="05D85BD000AD2EC9" modified="2008-04-29" version="1">MSFSVITQWNTQASIEGEFNRDHSVTFGSGQTVQASSAPEYKGNQERVNPEEQLLAALSSCHMLTFLTIAHLKRLPVQTYTDNASAILGKNAAGKIAIVKLVLKPEIVFQSGVDVSAEVLEKIHEKAHANCFIANSLSSEIEVIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP03</accession>
    <name>B1KP03_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BOF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327351.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4785"/>
    <dbReference type="EnsemblBacteria" id="ACA89034">
        <property type="protein sequence ID" value="ACA89034"/>
        <property type="gene ID" value="Swoo_4785"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4785"/>
    <dbReference type="eggNOG" id="COG3111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118907_1_1_6"/>
    <dbReference type="OMA" id="DRAWNGQ"/>
    <dbReference type="OrthoDB" id="1644884at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036700">
        <property type="entry name" value="BOBF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005220">
        <property type="entry name" value="BOF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04076">
        <property type="entry name" value="BOF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101756">
        <property type="entry name" value="SSF101756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764704" description="BOF domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="BOF" evidence="2">
        <location>
            <begin position="29"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="116" mass="12585" checksum="945772AF41933C87" modified="2008-04-29" version="1" precursor="true">MSKALAGSIILSCVLTLPAFAAYNGPGVETLVKSAKDASHATDDTPVELTGYLVKSLGDEKYLFRDQSGDVEVEIDNALWRNIEVNSDTKVTLKGEVDDEWQGIEIEIDSLKLVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP46</accession>
    <name>B1KP46_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 inner membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4828</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327394.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4828"/>
    <dbReference type="EnsemblBacteria" id="ACA89077">
        <property type="protein sequence ID" value="ACA89077"/>
        <property type="gene ID" value="Swoo_4828"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4828"/>
    <dbReference type="eggNOG" id="COG2095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079909_1_1_6"/>
    <dbReference type="OMA" id="IRMIFPQ"/>
    <dbReference type="OrthoDB" id="1323133at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA89077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="200" mass="21845" checksum="8C20214646E93670" modified="2008-04-29" version="1">MDTFSAAVMLFLIMDPLGNLPIFSSILRHIDPKKRRKVLIRELFFALIIMLLFLFAGEAILNFLNLKSESVSIAGGIILFLIAIRMIFPQPGGVVGLAAGEEPFIVPMAIPLMAGPSVLAALILLAHTDSTRMLDWTIALLAAWGVSAVILLFYKVFTKVLGEKGLTAVERLMGMVLVMISVQMFLDGIANYMAHIGQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP80</accession>
    <name>B1KP80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transport-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322999.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0349"/>
    <dbReference type="EnsemblBacteria" id="ACA84650">
        <property type="protein sequence ID" value="ACA84650"/>
        <property type="gene ID" value="Swoo_0349"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0349"/>
    <dbReference type="eggNOG" id="COG2823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083606_3_0_6"/>
    <dbReference type="OMA" id="RVKKVHN"/>
    <dbReference type="OrthoDB" id="1363906at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014004">
        <property type="entry name" value="Transpt-assoc_nodulatn_dom_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00749">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="43"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="121"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="20454" checksum="C27AD643546697A2" modified="2008-04-29" version="1" precursor="true">MIKTLSLIAVIFMLQGCAGAVMVGAVGGAMMVNDERSFSTQLDDTNADFQIASELAALEDVKNQANITGVVMNGNVLMIGQAPNSMLRDKAIRTVQAIEIGGKIHNQIRIGNPTSFTTRSNDTWITTKVKTRMLNTDNLDTTRIKVITENGEVFLLGIVQRDQADLAVDVARNTAGVRKVIKVFESPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP87</accession>
    <name>B1KP87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323006.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84657">
        <property type="protein sequence ID" value="ACA84657"/>
        <property type="gene ID" value="Swoo_0357"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0357"/>
    <dbReference type="HOGENOM" id="CLU_608195_0_0_6"/>
    <dbReference type="OrthoDB" id="2105626at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="450" mass="52945" checksum="868A5425E37CCE29" modified="2008-04-29" version="1">MYWKVEDKKWMKARKVLWAELKKCLLEHQYSKKEVKYMEPYFLKGIRKQEDIAWAEPVPLIYCLAWHPSDDINVWFAEFQRIKSEARCEESMLSSISTSYILIKNRSRLSTPLNATENVKSLFLQREQLLYQFLFLNKQFLDDPYVKQAEKWRLEELRPLNSGALFSIDKLAAIIKKDKEGEPFQPYFNAFSIQHLCHLSQYLSTEMYRRQMRWDDSEEKLGRMLATSLKFYQQRLQYSVAFQTIAELWFKQLDSDEIATEWKTIWVNAKSGKYLTRDEFFSKDKADEAGIENSKTNVEDELNQLLLDGTNRSEIIDCLADHFEAETIELFDINDLDNICSPYIGFIDPLEQLVKLRGGRDCVSYQDEVKDDVLTISLNEKVIGEINLDEVFSNETADYFQHIINLAMEWFPNQALLSVEEGSTSLFILPSNIFKLLKENEIESDLLTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP92</accession>
    <name>B1KP92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0362"/>
    <dbReference type="EnsemblBacteria" id="ACA84662">
        <property type="protein sequence ID" value="ACA84662"/>
        <property type="gene ID" value="Swoo_0362"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0362"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_17_1_6"/>
    <dbReference type="OMA" id="TYLGYPM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="8"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="153"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="396" mass="43514" checksum="A52BE87B982DE765" modified="2008-04-29" version="1">MFITMKKIRMGMVGGGQGAFIGAVHRIAAFLDGEIELVCGAFSSNPQRSIESGKALYLPEHRCYDSYQEMILCEEKLPEEMRMEFVVIVTPNHLHFPVAKMAIEHGFHVLSDKPATISLDEALRLKQLLEKHDQLYGLTQTYTGYPLIKQARHLIATGELGNIVKVVVEYSQGWLASKEDETSKQASWRLDEKQSGISCCMGDIGVHAANLAEYVSGLNMAELCADITSTVAGRTLDDDGTVLLKFSNGAKGVLLASQVALGDENNLKLRVYGDRKSVEWSQLESNTLWLKSNTEATQMIRAGVGDLCAAAKQAMRTPAGHPEGYLEAFANIYSNFAKQIRAKNAGEVCDNQLFDVPGIEQAVRGMAFIENVVQASASNEKWHPFSLKSDSNMGEE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH0</accession>
    <name>SUCC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="1">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="1">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sucC</name>
        <name type="ordered locus">Swoo_1839</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324469.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPH0"/>
    <dbReference type="SMR" id="B1KPH0"/>
    <dbReference type="STRING" id="392500.Swoo_1839"/>
    <dbReference type="EnsemblBacteria" id="ACA86123">
        <property type="protein sequence ID" value="ACA86123"/>
        <property type="gene ID" value="Swoo_1839"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1839"/>
    <dbReference type="eggNOG" id="COG0045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037430_0_2_6"/>
    <dbReference type="OMA" id="ITACDEV"/>
    <dbReference type="OrthoDB" id="316012at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="chain" id="PRO_1000129229" description="Succinate--CoA ligase [ADP-forming] subunit beta">
        <location>
            <begin position="1"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="1">
        <location>
            <begin position="9"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="321"/>
            <end position="323"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <sequence length="388" mass="41436" checksum="0EAB77B22F2705EC" modified="2008-04-29" version="1">MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKNEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRASRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLAGPQPYQARDLGFKLGLNPTQLKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALYRQPKIREMHDPSQDDAREAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVTVPVVVRLEGTNADLGREVLANSDLDIIAATSLTDAAEQVVKAAEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPN6</accession>
    <name>B1KPN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324535.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86189">
        <property type="protein sequence ID" value="ACA86189"/>
        <property type="gene ID" value="Swoo_1905"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1905"/>
    <dbReference type="eggNOG" id="ENOG5031T2F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_808661_0_0_6"/>
    <dbReference type="OMA" id="ETIMIED"/>
    <dbReference type="OrthoDB" id="1979339at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767281" evidence="2">
        <location>
            <begin position="23"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="37603" checksum="301FF64EB96376A3" modified="2008-04-29" version="1" precursor="true">MSILKKTLISICLISASGIVGATTVTGNVAVDNDFIVVHSPGNGSPNNVVYRGVHGSQWRNIESFNFNIKSDPRSLKTCSVSVIAWGDGKVSQGMSAILKADNAVYSGSGRFKAYQSNVTSSGWAQNGGPNASQINTLISASLANGQPPYNFSGTVASGTSPWGTLNFPLVNSVNSSNFRWIWSTSDLRKKTYSVFTTACDNLVKPKPVAVNMPGEHFQCYGVKEGDRLPNETIMIEDQFGKTRAVLGKPVLLCNPSSKQHKDKYFKIRNKERHLVCYNYVKQDKVRSQALEINNQFAPDQIVNGQRELFCVPSSKKHLSRINPGRPVKKEVGVSRPINFKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW5</accession>
    <name>B1KPW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Propeptide PepSY amd peptidase M4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325983.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3379"/>
    <dbReference type="EnsemblBacteria" id="ACA87648">
        <property type="protein sequence ID" value="ACA87648"/>
        <property type="gene ID" value="Swoo_3379"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3379"/>
    <dbReference type="eggNOG" id="ENOG502ZH66">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177055_0_0_6"/>
    <dbReference type="OMA" id="CRWTIAF"/>
    <dbReference type="OrthoDB" id="2046548at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767549" evidence="1">
        <location>
            <begin position="20"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="2">
        <location>
            <begin position="55"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="11981" checksum="ABD0B1DBC67B3A19" modified="2008-04-29" version="1" precursor="true">MKLGSILILTATLTTASLAPQTGQAKSAYQVMTTSAMTMAGQSSRQAKGQLRVKSTDQAIQLVKRQYRGKVLKAQSSRVNGNPGYRIKMLSNQGVVFYVSVDAKTGSVRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ00</accession>
    <name>B1KQ00_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4864</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327430.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4864"/>
    <dbReference type="ESTHER" id="shewm-b1kq00">
        <property type="family name" value="Proline_iminopeptidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89113">
        <property type="protein sequence ID" value="ACA89113"/>
        <property type="gene ID" value="Swoo_4864"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4864"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025429_1_0_6"/>
    <dbReference type="OMA" id="LNCAYWP"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="107"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_4" evidence="4">
        <location>
            <begin position="392"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="527" mass="57390" checksum="4AE33F3DC1664F20" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ77</accession>
    <name>B1KQ77_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0434"/>
    <dbReference type="EnsemblBacteria" id="ACA84732">
        <property type="protein sequence ID" value="ACA84732"/>
        <property type="gene ID" value="Swoo_0434"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0434"/>
    <dbReference type="eggNOG" id="ENOG502ZDZY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1947342_0_0_6"/>
    <dbReference type="OMA" id="EHLAHGC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14032" checksum="299063A3B153F2F9" modified="2008-04-29" version="1" precursor="true">MKLTPNLSLIEKLPSLVKLSSTGKANFSLFLGGLFLLCLSDAAPATLGGYLDISELIAVSDGLIIECLGVSLFGLFLVNPQIINQFWRLISYIFKLINGLNLVSRFPRFSSPVFKSCEQTAHGCRAPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB1</accession>
    <name>B1KQB1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent DNA helicase Rep</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rep</name>
        <name evidence="11" type="ordered locus">Swoo_0468</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323115.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0468"/>
    <dbReference type="EnsemblBacteria" id="ACA84766">
        <property type="protein sequence ID" value="ACA84766"/>
        <property type="gene ID" value="Swoo_0468"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0468"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004585_5_2_6"/>
    <dbReference type="OMA" id="HCANILI"/>
    <dbReference type="OrthoDB" id="137860at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01920">
        <property type="entry name" value="Helicase_Rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005752">
        <property type="entry name" value="Helicase_Rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01074">
        <property type="entry name" value="rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="10">
        <location>
            <begin position="281"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="648"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="22"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="670" mass="77164" checksum="D610C9063A0E0F60" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE9</accession>
    <name>B1KQE9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fumarate reductase cytochrome b subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0507</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323152.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0507"/>
    <dbReference type="EnsemblBacteria" id="ACA84804">
        <property type="protein sequence ID" value="ACA84804"/>
        <property type="gene ID" value="Swoo_0507"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0507"/>
    <dbReference type="eggNOG" id="ENOG502ZBTX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075821_0_0_6"/>
    <dbReference type="OMA" id="LLAHLHF"/>
    <dbReference type="OrthoDB" id="1073274at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00581">
        <property type="entry name" value="QFR_TypeB_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004224">
        <property type="entry name" value="Fum_red_B_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000177">
        <property type="entry name" value="Fumar_rd_cyt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="1 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000177-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="241" mass="26901" checksum="E6C90E33EA7D230C" modified="2008-04-29" version="1" precursor="true">MTIKTLLPTSSFAGLTGNPWSAKADKIQSATGLLLGCFLLAHLHFESSILLGKDAFYQVVQILEGGMFSESGHGFPLVTKIFSVFILLVVILHAAVALRRFPAQLGQWRALRRHMNGINHKDSHAWFWQLVTGFILFFLAPVHIFTMITNPEIGPHLSAERVYLDNAWLLYALLLPAVVIHAMIGLYRVAIKWGFTANRTGLRKVIKFMIIYLITIGVLSLVSYLFIGAELTTPVQPYVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQG0</accession>
    <name>B1KQG0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 11">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_0518</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323163.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="SMR" id="B1KQG0"/>
    <dbReference type="STRING" id="392500.Swoo_0518"/>
    <dbReference type="EnsemblBacteria" id="ACA84815">
        <property type="protein sequence ID" value="ACA84815"/>
        <property type="gene ID" value="Swoo_0518"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0518"/>
    <dbReference type="eggNOG" id="COG0113">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035731_0_0_6"/>
    <dbReference type="OMA" id="YQMDYAN"/>
    <dbReference type="OrthoDB" id="677575at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA84815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="338" mass="37449" checksum="113C9A9471929AE3" modified="2008-04-29" version="1">MNIITSAFPQRRMRRMRKHDFSRRLMAENQLSVNDLIYPMFVLEGNNRTEQIASMPGIERYSIDLLLKEAEEIVKLGIPLIALFPVTPAEKKTLLAEEAYNADALAQRAVRALKEAFPELGVMTDVALDPFTTHGQDGIIDEDGYILNDITTEILVKQALSHAEAGADIVAPSDMMDGRIGAIRQALEEAGHVNTQIMAYSAKYSSNYYGPFRDAVGSAGNLKGGNKHSYQMDPANSDEALHEVALDIQEGADMVMVKPGMPYLDIVTRVKRELAVPTFAYQVSGEYAMHMAAIENGWLSEKAIVMESLLCFKRAGANGVLTYFAKRAAQWLKEEQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQL9</accession>
    <name>B1KQL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1974</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324604.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1974"/>
    <dbReference type="EnsemblBacteria" id="ACA86258">
        <property type="protein sequence ID" value="ACA86258"/>
        <property type="gene ID" value="Swoo_1974"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1974"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033976_0_0_6"/>
    <dbReference type="OMA" id="HEYLEGY"/>
    <dbReference type="OrthoDB" id="410781at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10231">
        <property type="entry name" value="YegD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042054">
        <property type="entry name" value="YegD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="457" mass="49762" checksum="7867260D47C0E08B" modified="2008-04-29" version="1">MFVGFDYGSANCAVGVMQNSEVKLLPLTESSHYLTSTLYALDRELIAEAVHQQMPDSLKAEYAKARASQLTRARSARRELDLEPNEQAVFVGEQAVKAYLDMPEEGFYVRSPKSFLGATGLRADQVALFEDIVTMMMLHIKQEAESTRGLNAKGAITHAVIGRPVNFQGIGGEESNLQAESILRLAAKRAGFVDVDFLFEPLAAGMDYEASLDEDKLVLVVDVGGGTTDCSVVKMGPSHVDAKDRSQDFLGHSGQRIGGNDLDIALSMKAFMLHLGLGCHMVNGLPVPSKPFWNAVAVNDISAQRDFSSLNSRKTIEELIKDAKRPELLQRLLKVQKDQLGYRIVRSAEQVKISLSDADSVTANLDYVCPNLHAEVSQALFKEAIELPSAKIEALMKQALEIAGVKPDVIYVTGGTARSPAIYDKIAAMYPETPIVVGDHFGSVTAGLTRWAQKVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQV9</accession>
    <name>B1KQV9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3447</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326050.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3447"/>
    <dbReference type="EnsemblBacteria" id="ACA87715">
        <property type="protein sequence ID" value="ACA87715"/>
        <property type="gene ID" value="Swoo_3447"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3447"/>
    <dbReference type="eggNOG" id="COG0386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029507_2_2_6"/>
    <dbReference type="OMA" id="FPMMSKI"/>
    <dbReference type="OrthoDB" id="1635499at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="PTHR11592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="17996" checksum="DDBD28968E76B24A" modified="2008-04-29" version="1">MTTKIWDFTVNDIQGAESSLTDFKGKVLLIVNTASGCGFTPQYQGLQSLYEKFGPDKFAVLGFPCNQFGAQESGSNSEIQSFCELNFNVSFPMFQKIEVNGEDAHPLYQYLKSSAKGILGSQRIKWNFTKFLVDSDGKVLERFAPTTKPEALTKKIEELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ2</accession>
    <name>B1KQZ2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multidrug export protein MepA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326082.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3482"/>
    <dbReference type="EnsemblBacteria" id="ACA87748">
        <property type="protein sequence ID" value="ACA87748"/>
        <property type="gene ID" value="Swoo_3482"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3482"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_0_2_6"/>
    <dbReference type="OMA" id="LYFWGLP"/>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13143">
        <property type="entry name" value="MATE_MepA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045070">
        <property type="entry name" value="MATE_MepA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="449" mass="49119" checksum="19E9B1FE34B10091" modified="2008-04-29" version="1">MNPEISSQDLALVNDPIPKLLWRYTVPTILSMLVTGIYVAIDGMFVGHYLGETGLAGMMLAYPVGALLYAVGALLGMGGAALVSIYLGQGSVPKARKILGNTFSLCLIFGAFFAIFGSYFSRDILQLLGAEGAVLDSADDYLFWYYALGIFPIISVAFTALLRNDGRPGFVTGVLILGGCLNIVLDWLFIVVFPFELVGAAIATMMSQAVTGGLCLWHFLSDKTRLKITLSQMKLELDHCFNILKTGVPSFLMNLYLSIVLTLHNIAFLWVGSPLHVAAYGVVSYTEAFFYLVFEGIAFGTQPIFSFNAGAGRYDRVFKTLKIAFGITLVTAFLGLLFIYTKPQWVVYIFAGDNLELTPYAIEGMGLYFWGLPMEGLLLVGASFFQAINYSKEASMLTGAKLLLIAFVVYLFAWAFGTNGVWISLACCSSLLVIWMGFALRRVAKQLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRN8</accession>
    <name>B1KRN8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326136.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87803">
        <property type="protein sequence ID" value="ACA87803"/>
        <property type="gene ID" value="Swoo_3539"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3539"/>
    <dbReference type="HOGENOM" id="CLU_1833855_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="15797" checksum="E726539936E7F811" modified="2008-04-29" version="1">MSELKVKLKFHGEHHMGAETVEMVLPFEIDGYSALYSTNGHVVSSKNPRYLYLWDATVVLRIDLDIKAVGYLLPPKRKYISEFSESEDGYSFEVYGGNSKTTSTFMNYSGTNFKSGFGPVENGLFPSAHKPHVKYINENT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRR8</accession>
    <name>RLME_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase E</fullName>
            <ecNumber evidence="1">2.1.1.166</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA Um2552 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmE</name>
        <name evidence="1" type="synonym">ftsJ</name>
        <name evidence="1" type="synonym">rrmJ</name>
        <name type="ordered locus">Swoo_3569</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42720"/>
            <dbReference type="Rhea" id="RHEA-COMP:10202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10203"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.166"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.166" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326166.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRR8"/>
    <dbReference type="SMR" id="B1KRR8"/>
    <dbReference type="STRING" id="392500.Swoo_3569"/>
    <dbReference type="EnsemblBacteria" id="ACA87833">
        <property type="protein sequence ID" value="ACA87833"/>
        <property type="gene ID" value="Swoo_3569"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3569"/>
    <dbReference type="eggNOG" id="COG0293">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009422_4_0_6"/>
    <dbReference type="OMA" id="HRQTDHL"/>
    <dbReference type="OrthoDB" id="1798571at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000195021" description="Ribosomal RNA large subunit methyltransferase E">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01547"/>
        </source>
    </evidence>
    <sequence length="209" mass="23160" checksum="19B80DE97106485F" modified="2008-04-29" version="1">MSGKKRTASSSRWMQEHFDDHYVKLAQKRGFRSRAAFKIEEIQEKDKLIRPGMTVVDLGAAPGGWSQVAVKLAGDNGKVIACDILPMDPIVGVDFLQGDFREEKVLDALLTRVGDAKVDVVLSDMAPNMSGTGGVDQPRAMYLVELALDMCHQVLAPNGCFAVKVFQGEGFEEYMKSVREAFKTVKTRKPDSSRPRSREVYLVATGYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCY6</accession>
    <name>B1KCY6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MOSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322666.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0016"/>
    <dbReference type="EnsemblBacteria" id="ACA84317">
        <property type="protein sequence ID" value="ACA84317"/>
        <property type="gene ID" value="Swoo_0016"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0016"/>
    <dbReference type="eggNOG" id="COG2258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104911_2_0_6"/>
    <dbReference type="OMA" id="HSGVEKD"/>
    <dbReference type="OrthoDB" id="1877633at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="17"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="155" mass="17093" checksum="539943D194DFCC51" modified="2008-04-29" version="1">MPTLTAIGFKPVRQGPMTLVETAQVTKSAGVEQDFFGRPGKRQVTVMSQDQWNLVCLELDKPLPWVTRRANLLIQDYSFSSSDRGKLLKIGSLELLITGETDPCKKMEIAQAGLEKALTPDWRGGVTCRVLNDAQISQGDLVTISEVPEQLSFIS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-06-10" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD27</accession>
    <name>PROA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="1">GPR</shortName>
            <ecNumber evidence="1">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="1">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">proA</name>
        <name type="ordered locus">Swoo_3598</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326195.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KD27"/>
    <dbReference type="SMR" id="B1KD27"/>
    <dbReference type="STRING" id="392500.Swoo_3598"/>
    <dbReference type="EnsemblBacteria" id="ACA87862">
        <property type="protein sequence ID" value="ACA87862"/>
        <property type="gene ID" value="Swoo_3598"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3598"/>
    <dbReference type="eggNOG" id="COG0014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030231_0_0_6"/>
    <dbReference type="OMA" id="PGVCNAM"/>
    <dbReference type="OrthoDB" id="223669at2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0641">Proline biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000340919" description="Gamma-glutamyl phosphate reductase">
        <location>
            <begin position="1"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <sequence length="424" mass="45130" checksum="40993F86804952D6" modified="2008-04-29" version="1">MIENNELYLQTLGQNAKQASYGLASLTGTQKKALLSAIAASLTAKSQAILAANQKDVAAARENGLSEAMIDRLLLDDARLKGVISDIDNVISLNDPVGTELESQLLDNGLRLSRRRVPLGVIGVIYEARPNVTVDIAVLALKTGNAVILRGGKETLNSNMALSEAIREAITEQGLAADSVQLIKSPDRTLVSGLLKLDQFVDMIVPRGGQNLQRLCAEQATIPVILGGIGICHLYMDKDANIAKSIEVIANAKVQRPTVCNALDTVLIHDSLAETALPQLFSNLSAQGVSFYGCEQTKAIADKLGLAISTATDETYGQEWLSLTLGIKVVADIDTAIGHIRRYSSGHSEGILTDNIHASAHFINQVDSAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGLGEYTVRG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD43</accession>
    <name>NQRD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Na(+)-translocating NADH-quinone reductase subunit D</fullName>
            <shortName evidence="1">Na(+)-NQR subunit D</shortName>
            <shortName evidence="1">Na(+)-translocating NQR subunit D</shortName>
            <ecNumber evidence="1">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NQR complex subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NQR-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nqrD</name>
        <name type="ordered locus">Swoo_3614</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326211.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KD43"/>
    <dbReference type="SMR" id="B1KD43"/>
    <dbReference type="STRING" id="392500.Swoo_3614"/>
    <dbReference type="EnsemblBacteria" id="ACA87878">
        <property type="protein sequence ID" value="ACA87878"/>
        <property type="gene ID" value="Swoo_3614"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3614"/>
    <dbReference type="eggNOG" id="COG1347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046659_1_1_6"/>
    <dbReference type="OMA" id="CIIMGRF"/>
    <dbReference type="OrthoDB" id="1782047at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00428">
        <property type="entry name" value="NqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011292">
        <property type="entry name" value="NqrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30586:SF1">
        <property type="entry name" value="PTHR30586:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01939">
        <property type="entry name" value="nqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0915">Sodium</keyword>
    <keyword id="KW-0739">Sodium transport</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_1000191690" description="Na(+)-translocating NADH-quinone reductase subunit D">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00428"/>
        </source>
    </evidence>
    <sequence length="210" mass="22409" checksum="4BC8E485C68B8FFB" modified="2008-04-29" version="1">MANAKELKQVLSGPIVSNNPIALQVLGVCSALAVTSKMETALVMTIALTAVCACSNLFISMLRNHIPSSVRIIVQMTIIASLVIVVDQVLQAYAYDVAKQLSVFVGLIITNCIVMGRAEAYAMKTPPMMSFMDGIGNGLGYGAILLSVGFVRELFGNGSLFGVEILSKISDGGWYQPNGLLLLPPSAFFLIGTLIWIIRTVKPEQVEAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD72</accession>
    <name>B1KD72_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3645"/>
    <dbReference type="EnsemblBacteria" id="ACA87907">
        <property type="protein sequence ID" value="ACA87907"/>
        <property type="gene ID" value="Swoo_3645"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3645"/>
    <dbReference type="eggNOG" id="ENOG5031IBR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3157754_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="48" mass="5652" checksum="25C90E5597BBAB04" modified="2008-04-29" version="1">MKQLEAKLQDSEKVKVIDELDSVKHRLVVLEKLITDKGYEVNEEIRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDC4</accession>
    <name>B1KDC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0629"/>
    <dbReference type="EnsemblBacteria" id="ACA84925">
        <property type="protein sequence ID" value="ACA84925"/>
        <property type="gene ID" value="Swoo_0629"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0629"/>
    <dbReference type="HOGENOM" id="CLU_1650544_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766471" evidence="1">
        <location>
            <begin position="21"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="17765" checksum="D7D6E835C698C9AD" modified="2008-04-29" version="1" precursor="true">MKFRVLLVSLLICFAPASMAESLLWIKGNHSVIPDAVIKPSGELWLKGNSGTLPDAFVKNTQPVVQLQSQLSSQISEAKSDLIICRDNQIWLSGDMSQEPDAKLDKLGNVWLKGNDTDTPDANVSHDGFIWLINNYTNTADAAVRGGDNFKNAFIASVYLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD3</accession>
    <name>B1KDD3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UvrABC system protein A</fullName>
            <shortName evidence="13">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrA</name>
        <name evidence="16" type="ordered locus">Swoo_0638</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323281.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0638"/>
    <dbReference type="EnsemblBacteria" id="ACA84934">
        <property type="protein sequence ID" value="ACA84934"/>
        <property type="gene ID" value="Swoo_0638"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0638"/>
    <dbReference type="eggNOG" id="COG0178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001370_0_0_6"/>
    <dbReference type="OMA" id="PFEGIIP"/>
    <dbReference type="OrthoDB" id="152379at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0742">SOS response</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="603"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="743"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <begin position="643"/>
            <end position="650"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA84934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="945" mass="104517" checksum="710988E8B6A6C8C7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDE6</accession>
    <name>B1KDE6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldose 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0651</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>alpha-D-glucose = beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:10264"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="5.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the aldose epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323294.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0651"/>
    <dbReference type="EnsemblBacteria" id="ACA84947">
        <property type="protein sequence ID" value="ACA84947"/>
        <property type="gene ID" value="Swoo_0651"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0651"/>
    <dbReference type="eggNOG" id="COG2017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031753_2_0_6"/>
    <dbReference type="OMA" id="ATWLSCK"/>
    <dbReference type="OrthoDB" id="1512477at2"/>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019318">
        <property type="term" value="P:hexose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="80"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="175"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="37829" checksum="2518A7387DB88F09" modified="2008-04-29" version="1">MVRFRPLEPWEDPRGGLIERVRIDNGIIALEVLSLGGIIRSLWTPDKDGERSNIVLGCDSAEDYLAQGAHLGAIAGRYANRVANGQMSFEGNNYQLDTNQLTNCLHGGSEGFNRKQWHIGQLSDGVRLSLISPDGDMGFPGNCTVQLDYRLAGNNLYMEIFASTDKACPISLTQHSYFNLEGANASSNRDHTLQVDSQKHFILNELGLPTGIEEVSGGLLDFSQAKGFDIQEDKQFSSTGGIDHCYLLSTNSDELTRFGCLSSPKSGRSLTLYTNQPSVQIYGANFLEGEKGRGGQVLSKHQGICLEPQQIPDGPNQTKLFSDPWIKPDQVYHHISRYQFEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF0</accession>
    <name>B1KDF0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetylornithine aminotransferase</fullName>
            <shortName evidence="2">ACOAT</shortName>
            <ecNumber evidence="2">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argD</name>
        <name evidence="4" type="ordered locus">Swoo_0655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:18049"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.6.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323298.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0655"/>
    <dbReference type="EnsemblBacteria" id="ACA84951">
        <property type="protein sequence ID" value="ACA84951"/>
        <property type="gene ID" value="Swoo_0655"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0655"/>
    <dbReference type="eggNOG" id="COG4992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_1_6"/>
    <dbReference type="OMA" id="MVPNYNP"/>
    <dbReference type="OrthoDB" id="572533at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017652">
        <property type="entry name" value="Ac/SucOrn_transaminase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03246">
        <property type="entry name" value="arg_catab_astC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="107"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="225"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="405" mass="43238" checksum="8F75AA1A726E33D4" modified="2008-04-29" version="1">MSVNKTLTRAQFDDVMVPNYAPSAVIPVRGEGSRVWDQEGNEFIDFAGGIAVNCLGHCHPALVSALKEQGEKLWHLSNVMTNEPALALATKLVDATFADRVYFANSGAEANEAALKLVRRYAMDKFGAEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPQSITHVPFNDIAALEAVISDTTCAVMMEPLQGEGGIIDVDPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAYMRGDVVPDVLTTAKALGGGFPIAAMLTTKEIADHLKIGTHGSTYGGNPLACAIGNAVLDVVNTPEVLNGVKVREQLLRDGLNKINDKHQVFAEVRGQGLLLGAVLNDKYQGRAKEFLVASVGEGLMSLVAGANVIRFTPSLVIPEADIAEGLVRFERAVAKVVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDP5</accession>
    <name>B1KDP5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative serine protein kinase, PrkA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324787.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2158"/>
    <dbReference type="EnsemblBacteria" id="ACA86442">
        <property type="protein sequence ID" value="ACA86442"/>
        <property type="gene ID" value="Swoo_2158"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2158"/>
    <dbReference type="eggNOG" id="COG2766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028588_1_0_6"/>
    <dbReference type="OMA" id="DFYGMED"/>
    <dbReference type="OrthoDB" id="49410at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013153">
        <property type="entry name" value="Prk_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010650">
        <property type="entry name" value="PrkA_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016230">
        <property type="entry name" value="Ser_kinase_PrkA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08298">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06798">
        <property type="entry name" value="PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000549">
        <property type="entry name" value="Ser_prot_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00763">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_PrkA" evidence="1">
        <location>
            <begin position="19"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="644" mass="74314" checksum="6067441215EFC9FB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDS2</accession>
    <name>B1KDS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324813.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2187"/>
    <dbReference type="EnsemblBacteria" id="ACA86469">
        <property type="protein sequence ID" value="ACA86469"/>
        <property type="gene ID" value="Swoo_2187"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2187"/>
    <dbReference type="eggNOG" id="COG1876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081855_0_0_6"/>
    <dbReference type="OMA" id="GSRHHWG"/>
    <dbReference type="OrthoDB" id="1593541at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003709">
        <property type="entry name" value="Pept_M15B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02557">
        <property type="entry name" value="VanY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VanY" evidence="1">
        <location>
            <begin position="22"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="25555" checksum="D2302851EAEB669E" modified="2008-04-29" version="1">MLISPDALYGLDSEHLVDYQGHRLEPKTAQALASMTIAAKHQGIDIAVCSGHRHFNKQLQIWNAKAQGKRTLLDIDSHPVSIANKSQQEIVELILLWSALPGTSRHHWGTDVDLYDASAITSGELRLVSCEYEDNGPCAPLHRWLVKHSHEFGFYFPFQAGLSGVSPEPWHLSYFPVANELLKGFDTGRINAILNDADIELKSAIIPKLTHIINEYVQRVAPAPSATNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE40</accession>
    <name>B1KE40_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0014 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323373.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85026">
        <property type="protein sequence ID" value="ACA85026"/>
        <property type="gene ID" value="Swoo_0731"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0731"/>
    <dbReference type="eggNOG" id="COG0390">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076147_1_1_6"/>
    <dbReference type="OMA" id="PWYEPQY"/>
    <dbReference type="OrthoDB" id="1882150at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005226">
        <property type="entry name" value="UPF0014_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30028">
        <property type="entry name" value="PTHR30028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03649">
        <property type="entry name" value="UPF0014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="271" mass="29491" checksum="40E11B32895B262A" modified="2008-04-29" version="1">MESSIDIGWWQLTAFMSVLLIPLAINLKLQLKLGREISIAVIRMTVQLILVGLYLEFLFSLNSLFINSLWLSIMVLIGASAIITGAKLPKRALYLPVLTGLVIGVAPLMLILLLLLLKPQPLYSAQYLIPLAGMLLGNCLSGNIVALQRLFNALDEKKMEYEGILALGGTPYQGAFPFLQSALSQSLAPILASMTSMGLVTLPGMMTGQILGGSDPMLAVKYQLIILVAIFVTLTVSVTISLTLSIKRSITDTGLIKIKQLRLSHQRDKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEH8</accession>
    <name>B1KEH8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2275</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324899.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2275"/>
    <dbReference type="EnsemblBacteria" id="ACA86556">
        <property type="protein sequence ID" value="ACA86556"/>
        <property type="gene ID" value="Swoo_2275"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2275"/>
    <dbReference type="eggNOG" id="COG0033">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_8_1_6"/>
    <dbReference type="OMA" id="DIYKIYA"/>
    <dbReference type="OrthoDB" id="637615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05801">
        <property type="entry name" value="PGM_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005852">
        <property type="entry name" value="PGM_a-D-Glc-sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PTHR22573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01132">
        <property type="entry name" value="pgm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="11">
        <location>
            <begin position="40"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="12">
        <location>
            <begin position="210"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="13">
        <location>
            <begin position="321"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="10">
        <location>
            <begin position="488"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="550" mass="60003" checksum="6915B326A18343A9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI6</accession>
    <name>B1KEI6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324907.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2283"/>
    <dbReference type="EnsemblBacteria" id="ACA86564">
        <property type="protein sequence ID" value="ACA86564"/>
        <property type="gene ID" value="Swoo_2283"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2283"/>
    <dbReference type="HOGENOM" id="CLU_1546562_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="173" mass="19118" checksum="C2A01CC7CB9CE83B" modified="2008-04-29" version="1">MDNLDVVAILGTGATGFSFLMLFIGYKLTSDVQNKILDTSLLDFEPEKLKIWEEMAGKQLNNTRIFLGFTLLFLMAGLAILIHRPEAEVVLSLTPVEAEHPTILYIQNRKITLDENGKGLIVLKDEHALNIDNSTVFSKLSKLEAKLSASTTSENALIQQLSDNTNDSGFGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET9</accession>
    <name>B1KET9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326434.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3846"/>
    <dbReference type="EnsemblBacteria" id="ACA88104">
        <property type="protein sequence ID" value="ACA88104"/>
        <property type="gene ID" value="Swoo_3846"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3846"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_6"/>
    <dbReference type="OMA" id="TEYTDAD"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="27630" checksum="AB6A1D9665700980" modified="2008-04-29" version="1">MKNTVALIVGGSSGMGKEIAERLLRQGHSVMILSHDPIGLAEAKADLEKKTGGKVDTAEVDLYNSEAVAQFIARIKKEPRHINYLVNAAGFFKPVTFLEHSEKDYDLQLDINKSFFFITQAVAKNMQQHEGGSIVNIGSMWAHQAVKATPSSAYSMQKAGLHALTRNLAMELADYGVRVNAVAPSVVLSTIYKSFIAEDEIKETLQGFNDFHPIGRIGTTTDIADAIEFLLSDKASWITGTVMNIDGGVMAGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU9</accession>
    <name>B1KEU9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NMT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323447.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0805"/>
    <dbReference type="EnsemblBacteria" id="ACA85100">
        <property type="protein sequence ID" value="ACA85100"/>
        <property type="gene ID" value="Swoo_0805"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0805"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_9_0_6"/>
    <dbReference type="OMA" id="WDPYFAV"/>
    <dbReference type="OrthoDB" id="785019at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMT1" evidence="1">
        <location>
            <begin position="49"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="334" mass="37242" checksum="45EED5F64DA46841" modified="2008-04-29" version="1" precursor="true">MIMKVLLVFSILLSLIFIGIGVDQYIESKAVLEQQSTPVKIAVSTTPLSAPFIIAEKLSLFEKYNVLVNLYPTRGGHQCFKMLMNGDVDLATSSESVVMFNSFLRSDFSVLASFAESDNDLKVLSLESSSISEPHLLKGKSVGMVKSSASEYFIYAYMIITGNNTVDFNHVYMEPKDLGPALLSGEVDAISVWEPFGYQLNKEYGEQIRQFNTKGTHNLSFNLIAKKSLFANSLKQYVNVLAAISEAETFITSYPDETKVMVSDYLKIPMSELEWGWDDYIFRLSLSNVLLSNLQTQARWAIASGAVNKQGMPDFRLLIDSQALDILEHADKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW6</accession>
    <name>B1KEW6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ordered locus">Swoo_0822</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323464.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0822"/>
    <dbReference type="EnsemblBacteria" id="ACA85117">
        <property type="protein sequence ID" value="ACA85117"/>
        <property type="gene ID" value="Swoo_0822"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0822"/>
    <dbReference type="eggNOG" id="COG0225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_2_6"/>
    <dbReference type="OMA" id="PAACKFD"/>
    <dbReference type="OrthoDB" id="1554384at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="6"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="166" mass="18826" checksum="DEFFBD9E432DD2B5" modified="2008-04-29" version="1">MAVERAILAGGCFWGMQDLIRKREGVIATRVGYTGGDVVDATYRNHGTHAEGIEILFDNTRTSFNEILAFFFQIHDPSTPNRQGNDRGSSYRSAIFYDSNEQKEQAQKMIVRMDASGIWPGPVVTELVPAGDFWEAEPEHQDYLELRPNGYTCHFPRPDWVLPSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEZ0</accession>
    <name>B1KEZ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TRAP transporter solute receptor, TAXI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323488.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0846"/>
    <dbReference type="EnsemblBacteria" id="ACA85141">
        <property type="protein sequence ID" value="ACA85141"/>
        <property type="gene ID" value="Swoo_0846"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0846"/>
    <dbReference type="eggNOG" id="COG2358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033215_4_1_6"/>
    <dbReference type="OMA" id="TTGVYFP"/>
    <dbReference type="OrthoDB" id="991310at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42941">
        <property type="entry name" value="PTHR42941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02122">
        <property type="entry name" value="TRAP_TAXI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766517" evidence="1">
        <location>
            <begin position="21"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="32330" checksum="79BE9D5B4C22A3C0" modified="2008-04-29" version="1" precursor="true">MFNRMFALTLLFAFSSVISAENYSIGTGGQSGVYYPFGGALAKVWSEQVPDVNVKAEVTAASVENTIKVVRGDMIAGIAMGNVVLDAYKGEGKFKGKLPVKTLFALYPNLVHALTLDKSGITSLADLKGKRISLGAPASGTAVTSAALLESIGIDVKKDIDAVYLNYSETTNALANGQIDAGFIVGGQGVGAVTQIALTHKVNILPISAKESDAFIEAFPAYSSYTIPADTYNHVAAVPTLSVWNVLVVNAKMSDEMAYNLTKSAFENIEQVRKVVKAAEMTTPANANRLEGVPLHAGAQKYLDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF07</accession>
    <name>B1KF07_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0864</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323505.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0864"/>
    <dbReference type="EnsemblBacteria" id="ACA85158">
        <property type="protein sequence ID" value="ACA85158"/>
        <property type="gene ID" value="Swoo_0864"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0864"/>
    <dbReference type="eggNOG" id="COG1760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022305_0_1_6"/>
    <dbReference type="OMA" id="RMAMRRN"/>
    <dbReference type="OrthoDB" id="225730at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="3"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="183"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="48717" checksum="CA7EC44D5F2C6037" modified="2008-04-29" version="1">MFSAFDIFKIGVGPSSSHTVGPMKAAKEFVDELRQRGDMTKVTRVSVDIYGSLSLTGKGHHTDTAILMGLGGNLPESVDIEAIPEFIRQIETTETLPLGKEAKSVAFPTGSVTFHAYALPLHENGMSIHAWDGDTSLFSKTYYSTGGGFIVDEEHFGLEAANEVMVPYPFAFADDLLAICKETGMSISAVMLANEKAFNSEAVIYERLGAIWDTMKSGIERGCQTEGILAGPLRVPRRAPALYRQLVTGERHSSDPMAILDWVNMFALAVSEENAAGGRVVTSPTNGAAGIIPAVMAYYDKFIQPMTQSEYTRFYMAASAIGNLYKRNASISGAEVGCQGEVGVACSMAAAGLAEIMGATPSQVCIAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIASVKAINSSRMAMRRSSEPTVSLDKVIETMYETGKDMHVKYRETSQGGLAIKVTSICA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF56</accession>
    <name>B1KF56_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipoxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2318</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324939.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2318"/>
    <dbReference type="EnsemblBacteria" id="ACA86597">
        <property type="protein sequence ID" value="ACA86597"/>
        <property type="gene ID" value="Swoo_2318"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2318"/>
    <dbReference type="eggNOG" id="ENOG502Z9KW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_386795_0_0_6"/>
    <dbReference type="OrthoDB" id="114759at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="PTHR11771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="SSF48484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoxygenase" evidence="5">
        <location>
            <begin position="268"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="714" mass="81949" checksum="59F4308A49E8AFB5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE1</accession>
    <name>B1KFE1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326446.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3858"/>
    <dbReference type="EnsemblBacteria" id="ACA88116">
        <property type="protein sequence ID" value="ACA88116"/>
        <property type="gene ID" value="Swoo_3858"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3858"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_4_4_6"/>
    <dbReference type="OMA" id="GFTRPEF"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14715" checksum="4A3427E19F31FE10" modified="2008-04-29" version="1">MNKIWSPENIAPPAARYHHCAYVPANSDWLHIAGQLGFDLEGKLGSGVEEQVLFAWQNIDGLLLANQMEREDIVSVRVYLVDRDALPGYRAAMQRLFNKPSQVLPVTLLFVAGLFSPEWKVEIEVQAAKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFJ3</accession>
    <name>B1KFJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88168">
        <property type="protein sequence ID" value="ACA88168"/>
        <property type="gene ID" value="Swoo_3910"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3910"/>
    <dbReference type="eggNOG" id="ENOG5032GR9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177057_0_0_6"/>
    <dbReference type="OMA" id="TSANIYV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767021" evidence="1">
        <location>
            <begin position="23"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="103" mass="11390" checksum="5D00F3CB0CD0CBFE" modified="2008-04-29" version="1" precursor="true">MNKIIITAGLLFGSLLSGASYAHFSTIECNDCSASQRLQQADTNLVDQAHESIFVVDFVNHSVSKFQADGEVVKAVTMTLSENIDINHEYNHRKTFLRSVNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK7</accession>
    <name>B1KFK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326512.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3924"/>
    <dbReference type="EnsemblBacteria" id="ACA88182">
        <property type="protein sequence ID" value="ACA88182"/>
        <property type="gene ID" value="Swoo_3924"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3924"/>
    <dbReference type="HOGENOM" id="CLU_2525705_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="84" mass="9931" checksum="6BE114443CBB0C1D" modified="2008-04-29" version="1">MNVNEITRQEWEESSTLSPTQENIKFFRLEDWETLEIETEIENIKDYAKALQRVAQKIKSHGYGIIEAKRNDKDDAWLCKCITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG25</accession>
    <name>B1KG25_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2455"/>
    <dbReference type="EnsemblBacteria" id="ACA86732">
        <property type="protein sequence ID" value="ACA86732"/>
        <property type="gene ID" value="Swoo_2455"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2455"/>
    <dbReference type="eggNOG" id="ENOG5032U7P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1524142_0_0_6"/>
    <dbReference type="OMA" id="AKRETKY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="212" mass="23563" checksum="558B9B61038F0D12" modified="2008-04-29" version="1" precursor="true">MMSSEKKEAKRETKYSRLWGVLVVLVISFVAWKVQPISLKIEDPVEKAASLLGTLIFLSLFVERAIEVFLSAWRSAGADELDREIAIRMLAVEKYLQSQPDKLAAEESSQYKSLSTSLEEIEKERAEYRAGSRFISQWLGLGMGMMIAFIGIRIIGTIVNVEQANLEGYQAALFLIIDIIFTGAVLAGGSDSINKIMKVYNSVMAKTVKQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG34</accession>
    <name>B1KG34_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325083.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2464"/>
    <dbReference type="EnsemblBacteria" id="ACA86741">
        <property type="protein sequence ID" value="ACA86741"/>
        <property type="gene ID" value="Swoo_2464"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2464"/>
    <dbReference type="eggNOG" id="COG1227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025243_0_1_6"/>
    <dbReference type="OMA" id="IMLCAIL"/>
    <dbReference type="OrthoDB" id="732679at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="8">
        <location>
            <begin position="179"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="33416" checksum="059ECD03D54B2544" modified="2008-04-29" version="1">MSVYVVGHKIPDSDSICGAIALAYLKNQIGEAAIAARLGELSPETAFILEKFGFEAPEFKTSYAGEEVYIVDHSELTQAPDDIAEATIVGIVDHHKLGDLTTSTPLECWIRPVGCSNTIIKMMYDFHNVEIPQDIAGIMMCAILSDTVIFKSPTCTTADIKCVEALAEIAGIEDFKAVGMEMFKVKSAVEGTPARDLVMRDFKDFNMNGNKIGIGQLEVIDLSVFDDIKAELEADIAALKAEGERHSVILLLTDIMKEGSELLVVSDDSNLIERAYGKACENDRVWLDGVLSRKKQIVPQLQEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG51</accession>
    <name>B1KG51_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Replication-associated recombination protein A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325100.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2481"/>
    <dbReference type="EnsemblBacteria" id="ACA86758">
        <property type="protein sequence ID" value="ACA86758"/>
        <property type="gene ID" value="Swoo_2481"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2481"/>
    <dbReference type="eggNOG" id="COG2256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017985_1_1_6"/>
    <dbReference type="OMA" id="RIILSQC"/>
    <dbReference type="OrthoDB" id="977094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="48"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="443" mass="49152" checksum="2C3B0BE46B58C4E0" modified="2008-04-29" version="1">MSSFSFDFAPDFRPLAARMRPEELSQYIGQSHLLGEGKPLRKALEAGRAHSMMFWGPPGTGKTTLAELVANYANAHVERISAVTSGVKEIRTAIEHAKNVAESRGQRTLLFVDEVHRFNKSQQDAFLPFIEDGTVIFIGATTENPSFEINNALLSRARVYLIKKLTNDEIVLIVNQALLDVERGLGKRKLTIPDAVANKLANVCDGDARKALNLIELMSDMVADGESFTEEMIVEVAGQQLAGFDKNGDQYYDLISAVHKSIRGSAPDAALYWFCRMLEGGCDPLYIARRLLAIASEDIGNADPVAMTVAINAWECFHRVGPSEGERAIAQAIIYLASAPKSNAVYTAFKAARQLARETGQDAVPEHLRNAPTQLMKDIGFGEGYRYAHDEPNSYASGECYFPERLAGSRFYYPTEHGFEKRIKSKLEQLTQLDNDSEIKRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG75</accession>
    <name>B1KG75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326542.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3955"/>
    <dbReference type="EnsemblBacteria" id="ACA88212">
        <property type="protein sequence ID" value="ACA88212"/>
        <property type="gene ID" value="Swoo_3955"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3955"/>
    <dbReference type="eggNOG" id="ENOG50334MN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160720_0_0_6"/>
    <dbReference type="OMA" id="LMRDEDY"/>
    <dbReference type="OrthoDB" id="2028462at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="13659" checksum="5EB7ED4CE9A5893B" modified="2008-04-29" version="1">MDNEKQYLFDNPKNIQRVLYLLYACCTLLVILDFVIHRHVYHSWENLPIFYPIYGFVGCVILVLIASWMRTFLMRPEGYYDEPEADDNNHSTPTSDDDAVSGHATDAKKDIGDRNVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG84</accession>
    <name>B1KG84_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3964</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CpxP/Spy family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326551.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3964"/>
    <dbReference type="EnsemblBacteria" id="ACA88221">
        <property type="protein sequence ID" value="ACA88221"/>
        <property type="gene ID" value="Swoo_3964"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3964"/>
    <dbReference type="eggNOG" id="ENOG5033JVE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1824011_0_0_6"/>
    <dbReference type="OMA" id="KNEMDEV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012899">
        <property type="entry name" value="LTXXQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07813">
        <property type="entry name" value="LTXXQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764845" evidence="5">
        <location>
            <begin position="24"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="141" mass="16272" checksum="7244A298916A8C14" modified="2008-04-29" version="1" precursor="true">MKKRVLNILLASFFTVFAVTASAGDGSEKHTQAEQQIEEIKARLNLTEEQKEQVTPIFKKSMEKRQSTLKSYGIDLENQKTKSGQKIGFREARKLKNEMDEVRSHTLTELKTVLTDEQLVEYEEIQEEIASKIRSRIRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGD8</accession>
    <name>B1KGD8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326604.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4019"/>
    <dbReference type="EnsemblBacteria" id="ACA88275">
        <property type="protein sequence ID" value="ACA88275"/>
        <property type="gene ID" value="Swoo_4019"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4019"/>
    <dbReference type="HOGENOM" id="CLU_1453485_0_0_6"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="21337" checksum="6FCA601EB2F6144A" modified="2008-04-29" version="1">MNIIDIKLTNGFDRSVVEDLVFFSLLPFKNYSQETLVSFFIECMSSMDLNIATLHVLQIENKPTAFAFILDAFEGQNDSAPHLHVLSVFPSKQKLNIGSEFLQCVIAKNNFTGLTLECDENTIPFFAKNNFTKRDVTLECGQYSMFYGDAEKKDRFKRPQVEGEALEKYLNDYYACSQRLEEKGHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGI5</accession>
    <name>B1KGI5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Co-chaperone protein DjlA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">djlA</name>
        <name evidence="10" type="ordered locus">Swoo_1020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Single-pass type III membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The transmembrane domain is a dimerization domain.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323660.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1020"/>
    <dbReference type="EnsemblBacteria" id="ACA85313">
        <property type="protein sequence ID" value="ACA85313"/>
        <property type="gene ID" value="Swoo_1020"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1020"/>
    <dbReference type="eggNOG" id="COG1076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066221_1_0_6"/>
    <dbReference type="OMA" id="MQYWGKL"/>
    <dbReference type="OrthoDB" id="1528212at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01153">
        <property type="entry name" value="DjlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023749">
        <property type="entry name" value="DjlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Periplasmic" evidence="7">
        <location>
            <begin position="1"/>
            <end position="6"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="7">
        <location>
            <begin position="31"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="193"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="259" mass="29198" checksum="2BD04F9A5897752C" modified="2008-04-29" version="1">MRIWGKFFGFAIGFMFGRIIGGVIGLWLGHLYDKKSAQLSGIIGSGANRQTLFFKTTFSVMGHVAKASGQVTETDIRIATMLMDQMQLKGEARAEAQAAFKEGKESDFDVKACLKTFRLISMGRKELLQMFLEIQIQTALSDAKLDPKEHEILLTIAQELGFSRIQLDELLKRWQAEFNFHQGGNNNQTSIEDAYSLLGLTEASSDQEVKRSYRKLMNEHHPDKLVAKGLPPEMMELAKTKAQDIQAAYDRVKTDRGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGI7</accession>
    <name>B1KGI7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1022</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323662.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1022"/>
    <dbReference type="EnsemblBacteria" id="ACA85315">
        <property type="protein sequence ID" value="ACA85315"/>
        <property type="gene ID" value="Swoo_1022"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1022"/>
    <dbReference type="eggNOG" id="COG1052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_6"/>
    <dbReference type="OMA" id="PHIAWAY"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="4">
        <location>
            <begin position="24"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="5">
        <location>
            <begin position="111"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="320" mass="34087" checksum="53158AA40D9EF577" modified="2008-04-29" version="1">MKIVVLDGHTLNPGDLSWCGLSELADEGEFICYERTAESELLSRAQDAEIIFTNKTPLNAQVLSQLPKLTYIGVLATGTNVVDLVAAASHGMVVTNVPSYAPDAVAQMVFAHIFHHTQGVASHHQAVVQGAWSQCPDFCFTLSPLQSLKGKTIGLMGYGAIGQQVANIALAFGMKVLVNTRTPLLDLPTGAIWSELSDMLPQVDILSLHCPLTLETDKIVNRALLKSMRKTAILVNTARGGLIDEVALSQALADGDIAAAGLDVLSTEPPLDNNPLLNAINISITPHNSWATLEARQNLLNIAVNNLAAFLAGKADNQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL7</accession>
    <name>B1KGL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1052</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323691.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1052"/>
    <dbReference type="EnsemblBacteria" id="ACA85345">
        <property type="protein sequence ID" value="ACA85345"/>
        <property type="gene ID" value="Swoo_1052"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1052"/>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031614_0_0_6"/>
    <dbReference type="OMA" id="WGIFYQV"/>
    <dbReference type="OrthoDB" id="470322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="25"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="510" mass="56319" checksum="B51580D87924F447" modified="2008-04-29" version="1">MSDSKDAYADNDLREVKQLGMWASIASLSYIFWIVGGMELVERIAYYGVKASAGLYAKAPVSEGGLGISLSDYGVIIAIWAFMQTFIPVFTGGISDRVGYKETIFASTIIKIAGYLMMAFFPSFYGFLFGAILLAAGTGIFKPGIQGTLVLSTGRQNTSMAWGIFYQVVNIGGFLGPLVAVHMRQLSWDNVFYACAAIISLNFLFLLAYKEPGKEERLERKRKIKAGELHQEVLWKDAWHELKKPIVIYYMLVFAGFWFLFNSLFDVLPIHIAEWVDTSVIVTSLFGPEGTSNGILQFWLGLDNTGTKVMPEGMLNLNAGMIMTSCFLVAALTAKYRITTAMLGGCLMSILAFVLIGATNAAWMMVLAIAMFSFGEMMISPKKNEFMGNIAPEGKKAMYLGFVMLPQGIGWTLEGYFGPKLYEMFASKEIFSLQLLAERGMNQSEIDAIPQGEAFTTLVSYTGESAQSLTTLLYNTHDIGMAWYIIAAIGTISAVGIYLYGKWLLKLQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM0</accession>
    <name>B1KGM0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323694.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1055"/>
    <dbReference type="EnsemblBacteria" id="ACA85348">
        <property type="protein sequence ID" value="ACA85348"/>
        <property type="gene ID" value="Swoo_1055"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1055"/>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_464459_0_0_6"/>
    <dbReference type="OMA" id="VAIIFRQ"/>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="365"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="8">
        <location>
            <begin position="457"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="598" mass="67058" checksum="768626D85EE35D58" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN2</accession>
    <name>B1KGN2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_S24 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323706.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1067"/>
    <dbReference type="EnsemblBacteria" id="ACA85360">
        <property type="protein sequence ID" value="ACA85360"/>
        <property type="gene ID" value="Swoo_1067"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1067"/>
    <dbReference type="eggNOG" id="COG2932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158568_0_0_6"/>
    <dbReference type="OMA" id="VIYHTSE"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S24" evidence="1">
        <location>
            <begin position="6"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="10516" checksum="4221A16312D6D55C" modified="2008-04-29" version="1">MFGVNICRVSGVSMQPRIPAGSFVLCMGALRTKLKPGGIYLFEHPRLGQLIKTLSNVDSAGNLWFKGENSHSVSMQEMGPIRQNRVIGKVTWVISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS2</accession>
    <name>B1KGS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion system effector, Hcp1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325132.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2514"/>
    <dbReference type="EnsemblBacteria" id="ACA86791">
        <property type="protein sequence ID" value="ACA86791"/>
        <property type="gene ID" value="Swoo_2514"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2514"/>
    <dbReference type="eggNOG" id="COG3157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116190_1_0_6"/>
    <dbReference type="OMA" id="WEHTTAG"/>
    <dbReference type="OrthoDB" id="1153621at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036624">
        <property type="entry name" value="Hcp1-lik_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008514">
        <property type="entry name" value="T6SS_Hcp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05638">
        <property type="entry name" value="T6SS_HCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141452">
        <property type="entry name" value="SSF141452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03344">
        <property type="entry name" value="VI_effect_Hcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="172" mass="19168" checksum="7E719A3120D3AC19" modified="2008-04-29" version="1">MPTPCYISIKGQTQGDITAGAFTADSVGDIFVEGHEDEMLVQEFDHIVTVPTDPQSGQPSGQRVHKPFKFTVALNKAVPLMYNSLASGEKITEVELKWYRTSVEGKQEHYFSTKLEGATIIDIQCQMPHCQDPNKSDFTQLVTVSMAYRKIDWDHTVAGTSGSDDWRKPIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH26</accession>
    <name>B1KH26_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Bifunctional adenosylcobalamin biosynthesis protein</fullName>
            <ecNumber evidence="12">2.7.1.156</ecNumber>
            <ecNumber evidence="12">2.7.7.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_4082</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 12">Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15769"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15765"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>adenosylcob(III)inamide phosphate + GTP + H(+) = adenosylcob(III)inamide-GDP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.7.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 12">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 12">Belongs to the CobU/CobP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.156" evidence="12"/>
    <dbReference type="EC" id="2.7.7.62" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326667.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4082"/>
    <dbReference type="EnsemblBacteria" id="ACA88338">
        <property type="protein sequence ID" value="ACA88338"/>
        <property type="gene ID" value="Swoo_4082"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4082"/>
    <dbReference type="eggNOG" id="COG2087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094161_0_1_6"/>
    <dbReference type="OMA" id="DCLTVWL"/>
    <dbReference type="OrthoDB" id="1903913at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036429">
        <property type="term" value="F:adenosylcobinamide kinase (ATP-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036428">
        <property type="term" value="F:adenosylcobinamide kinase (GTP-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008820">
        <property type="term" value="F:cobinamide phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003203">
        <property type="entry name" value="Cobinamide_kinase/P_G-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34848">
        <property type="entry name" value="PTHR34848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02283">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006135">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="12 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="13">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00007490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA88338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="180" mass="20182" checksum="045C546E00129FCD" modified="2008-04-29" version="1">MNHLILGGARSGKTRFATQAAVALAAKGYECVYLATAQALDSEMHERITRHQLDREQDSIEWLTYETPFELVETLKAIARDNRVIVVDCLTLWLTNHLLIEPKTQSEERWRKAKTMLLQALPSLPGEVYLVSNEVGCGIVPMGELSRRFVDEAGWLHQDIAKIADEVVLVTAGLPMRLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH73</accession>
    <name>B1KH73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1088"/>
    <dbReference type="EnsemblBacteria" id="ACA85381">
        <property type="protein sequence ID" value="ACA85381"/>
        <property type="gene ID" value="Swoo_1088"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1088"/>
    <dbReference type="eggNOG" id="ENOG5031J4I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2131835_0_0_6"/>
    <dbReference type="OMA" id="DIRYYFF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="13215" checksum="715A6BF906F58B0F" modified="2008-04-29" version="1">MTKYMDLLNYLINELLQYIVVVILFLTLIKVMFKLVKWGRGMSKGAFLFLAIFPLISFFPIPPPQFKNVEKAKQEQRKIKEDSGDPPDEGLDENSFNKLLKKMQKAWFSLQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHB9</accession>
    <name>B1KHB9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ornithine carbamoyltransferase</fullName>
            <ecNumber evidence="6">2.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323773.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1134"/>
    <dbReference type="EnsemblBacteria" id="ACA85427">
        <property type="protein sequence ID" value="ACA85427"/>
        <property type="gene ID" value="Swoo_1134"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1134"/>
    <dbReference type="eggNOG" id="COG1177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_3_0_6"/>
    <dbReference type="OMA" id="FPMFVWG"/>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="64"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="275" mass="30585" checksum="9FBF7A8CB72B35BE" modified="2008-04-29" version="1" precursor="true">MSNRLKKMSFSTIMLWAGMFFLYAPMFILVIYSFNESKLVTVWGGFSPKWYGELFRDQQILDAVWTSLRVAFFASTMAVILGTMAAFVMTRFKRSWGKMTLSNMITAPLVMPEVITGLSLLLLFVHMADLFGWPAERGMLTVWIAHSTFCAAYVAVVVSARLRELDQSIEEAAQDLGATPLKTFFYITVPMITPSLMAGWLLSFSLSLDDLVIASFASGPGATTLPMVVFSSVRMGVSPKINALATLIILTVSLIAFISWYFARRSEKKSLPPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHC3</accession>
    <name>B1KHC3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine pyrophosphate protein domain protein TPP-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323777.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1138"/>
    <dbReference type="EnsemblBacteria" id="ACA85431">
        <property type="protein sequence ID" value="ACA85431"/>
        <property type="gene ID" value="Swoo_1138"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1138"/>
    <dbReference type="eggNOG" id="COG1013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048564_0_0_6"/>
    <dbReference type="OMA" id="NTVHGRM"/>
    <dbReference type="OrthoDB" id="981516at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="1">
        <location>
            <begin position="65"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="350" mass="37938" checksum="F9D41D94F95DFBCC" modified="2008-04-29" version="1">MSYIKPQFKHPRLQVNDLGLTHRDYEGALSTLCAGCGHDSITSAVAQACAELSLPPHKIAKLSGIGCSSKAPTYFLNNAHGFNTVHGRMPSVATGANMANRELIYLGMSGDGDSASIGFGQFAHVVRRRLNMLYMVANNGVYGLTKGQLAATAEQGMKSKSGEASLFTDIDLCVSALQFGATFVARSFSGDKSQLVPLIKAAISHKGFAFIDIISPCVTFNNNPDSNRSYDYVHDHITTAAVADFVPVKQEIRCENGQSDSEDICLHDGSILRLSRIDADYDAHDRIKAMTKIEQLKSEGKILTGLMYIDPEADDYHEINGTSDAPLNSLKQETLCPGSHVLKTINESFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHM2</accession>
    <name>B1KHM2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PpiC-type peptidyl-prolyl cis-trans isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325247.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2630"/>
    <dbReference type="EnsemblBacteria" id="ACA86907">
        <property type="protein sequence ID" value="ACA86907"/>
        <property type="gene ID" value="Swoo_2630"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2630"/>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034646_9_1_6"/>
    <dbReference type="OMA" id="RADCERY"/>
    <dbReference type="OrthoDB" id="1838755at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="113"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="29837" checksum="BDB431E47C26F86A" modified="2008-04-29" version="1">MSLCGTNPSTTPSKERLPVISVNGVLIEETQLANELQYHPHGEFDVVVQRAGQALVIQQLLLEQAVKEGIDVSGESEEAGVQLLLQTQVKYDDPDEDDCLRYFKNNRDKFTTAPLMEVDHILLAAANDDLDARDDAKSDAMDIISTLKNDLKLFGELAKHHSVCPSKETGGSLGQISNGQTVPEFERQLMMLPEGLAEKPLESRYGLHVVNVARKVEGKALDYSLVQDKVRGYLVHRASHLAIQAYIHGLVQKADIQGVEVKFSEDNVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS0</accession>
    <name>B1KHS0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4142</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326727.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4142"/>
    <dbReference type="EnsemblBacteria" id="ACA88398">
        <property type="protein sequence ID" value="ACA88398"/>
        <property type="gene ID" value="Swoo_4142"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4142"/>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065535_0_0_6"/>
    <dbReference type="OMA" id="SMAGWQQ"/>
    <dbReference type="OrthoDB" id="1015149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="8">
        <location>
            <begin position="168"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="380" mass="41948" checksum="612C1E14BD98742E" modified="2008-04-29" version="1">MELLRIDCLGKELRLEGSMAGWQQLFWGGELVSVKQASADNEGLKNHQFELRSQPAEIDSNQAVSADSITSTEQVKTILVNLEIDLQWQPFNLDYRLIVDDNIVTTGTRNSKDIERQTPVNPIEVKRQFSLVGLASLGFKLLKSAKVIKVVLAGASVAAYSWLFSFQFALALIACLVFHEYGHIRAMKYFGMKTKGIYLIPFMGGLALSDEKINTRWQDVVISIMGPTFGLLMSVMALVAFWITDNPFFAGLAAFNALLNLFNLLPILPLDGGHILKSVSFSMNSIMGLAACVAGAAIGVYISYTLGLALLGFLLLIGSAEIVFEWKTRHQSHLLPLDRYGQIFSTIWYLLTVGSLIGIIWYLAGTGDDMLSLPLQILQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHX1</accession>
    <name>B1KHX1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326778.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4193"/>
    <dbReference type="EnsemblBacteria" id="ACA88449">
        <property type="protein sequence ID" value="ACA88449"/>
        <property type="gene ID" value="Swoo_4193"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4193"/>
    <dbReference type="eggNOG" id="COG3151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116657_1_0_6"/>
    <dbReference type="OMA" id="NAAMHQP"/>
    <dbReference type="OrthoDB" id="1615657at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009659">
        <property type="entry name" value="DUF1249"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38774">
        <property type="entry name" value="PTHR38774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06853">
        <property type="entry name" value="DUF1249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="150" mass="17225" checksum="DFB6AE6A4CD72F4B" modified="2008-04-29" version="1">MARPLNGNLNTKRYQPDINKFLSLCGRNYFHILRWLPSDASQGDAWVVEEGIGCLNVRLLENTSYTQLIEISRCVGKSDYIHSPCVSVRVYHDAKLAEVLTSRQISRLSPVYDYPNIRMYHRDEKYQVNAFLEELLKIGGHMSAICLSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ5</accession>
    <name>B1KHZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323819.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1180"/>
    <dbReference type="EnsemblBacteria" id="ACA85473">
        <property type="protein sequence ID" value="ACA85473"/>
        <property type="gene ID" value="Swoo_1180"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1180"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064910_0_0_6"/>
    <dbReference type="OMA" id="IMFLDIV"/>
    <dbReference type="OrthoDB" id="1917125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="241" mass="26467" checksum="B5C44E5D614E19E1" modified="2008-04-29" version="1">MELLLDPNAWLALLTLTVLEIILGIDNIIFISILVGRLPEHQRERARILGLGLAMLTRILLLISIAWVMKLTEPFITVMEHGVSGRDLILLFGGLFLIYKSTSEIHGCLEGEGETAPKARGSSFFFVLIQIAILDIVFSLDSVITAVGMADDVEVMILAIVIAVGVMMFAAKSVGDFVERHPTVKMLALTFLTLIGFTLLAEGFGVHIPKGYIYFAMGFSIAVEMLNLRVKSKRKEETSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI63</accession>
    <name>B1KI63_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amphi-Trp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323887.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1249"/>
    <dbReference type="EnsemblBacteria" id="ACA85541">
        <property type="protein sequence ID" value="ACA85541"/>
        <property type="gene ID" value="Swoo_1249"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1249"/>
    <dbReference type="eggNOG" id="ENOG50334ZG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183805_0_0_6"/>
    <dbReference type="OMA" id="EEIEFQI"/>
    <dbReference type="OrthoDB" id="2022191at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027598">
        <property type="entry name" value="Amphi-Trp_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20068">
        <property type="entry name" value="Amphi-Trp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04354">
        <property type="entry name" value="amphi-Trp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amphi-Trp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="74" mass="8829" checksum="165903F8C9AA2381" modified="2008-04-29" version="1">MSKKEDRDIEKDYPTAEFVAKLRRLADSLESGSKFEIQIAGERIYVPVRAKYNIEHEREGDEEEIEFQIKWTHE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-06-10" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI99</accession>
    <name>DDL_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="2">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ddl</name>
        <name type="ordered locus">Swoo_2674</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="ACA86950" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86950.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_041418165.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI99"/>
    <dbReference type="SMR" id="B1KI99"/>
    <dbReference type="STRING" id="392500.Swoo_2674"/>
    <dbReference type="EnsemblBacteria" id="ACA86950">
        <property type="protein sequence ID" value="ACA86950"/>
        <property type="gene ID" value="Swoo_2674"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2674"/>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039268_0_0_6"/>
    <dbReference type="OMA" id="IDFFLTD"/>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000341172" description="D-alanine--D-alanine ligase">
        <location>
            <begin position="1"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="124"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="154"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="335" mass="37321" checksum="70EA9D910A16C81E" modified="2008-06-10" version="2">MSQINLLLLCGGGGDEHAISLMSADFLETSLAKEPEINLLRVELDGQGHYRTQDGRSCELTNRKEIRFAAEEQAPWPVDYVIPCIHGFPGETGDIQSYFDLIKLPFFGCDSESSSNCFNKVTAKMWFSALGVPNTPYIFLNELNQESIAQTKQALENWGSIFIKAASQGSSVGCYRVDSQDELVSSLEQAFSFSPYVIVEKTINARELEVAAYELNGEIVATKPGEIICASNTFYSFDEKYAANSKAETKVEADVSEEVAQQIQAYAIKVFKGMKLSHLSRIDFFLTEDNEILLNEINTFPGLTPISMFPKMLQNHGDDFTHYLYSNIKSQLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIF5</accession>
    <name>B1KIF5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidoglycan-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pal</name>
        <name evidence="13" type="ordered locus">Swoo_2730</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Pal lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325343.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2730"/>
    <dbReference type="EnsemblBacteria" id="ACA87006">
        <property type="protein sequence ID" value="ACA87006"/>
        <property type="gene ID" value="Swoo_2730"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2730"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016890_9_4_6"/>
    <dbReference type="OMA" id="MNQGEET"/>
    <dbReference type="OrthoDB" id="1544679at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02204">
        <property type="entry name" value="Pal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006690">
        <property type="entry name" value="OMPA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039001">
        <property type="entry name" value="Pal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014169">
        <property type="entry name" value="Pal_lipo_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02802">
        <property type="entry name" value="Pal_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01068">
        <property type="entry name" value="OMPA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6 13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766651" description="Peptidoglycan-associated protein" evidence="11">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="12">
        <location>
            <begin position="65"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="19538" checksum="3437ED2D37406D84" modified="2008-04-29" version="1" precursor="true">MDLNKLFKAMLVAIPMMAISACSSTSDSETDATSSNSSSGSELTTGGVETGGVAPVLTPQEQQRLKYQELRKEHIIYFDFDRSSVSAQFAEVLQAHGEYLIEHPNVRVMIEGHADERGTPEYNIALGERRAKAVAKYLQGMGVLPSQMSIVSYGEEKPLDMSRTDDGFAVNRRAVLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM2</accession>
    <name>B1KIM2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326845.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4262"/>
    <dbReference type="EnsemblBacteria" id="ACA88518">
        <property type="protein sequence ID" value="ACA88518"/>
        <property type="gene ID" value="Swoo_4262"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4262"/>
    <dbReference type="eggNOG" id="ENOG5032C3W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1531521_0_0_6"/>
    <dbReference type="OMA" id="INCCIIL"/>
    <dbReference type="OrthoDB" id="2097271at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766663" evidence="1">
        <location>
            <begin position="18"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="19958" checksum="A5B14DDF160A4790" modified="2008-04-29" version="1" precursor="true">MRFINCCIILFSFNCFAGDNLESLDENEGYVILPLVISGMLPKSITLEEASVFGNSYKVKDIKIGENFELITLPAGDYKWTKIQINKSYYFNLEEYGYDIKVNKGVVNYGGHLIIDFNAQFGTARYNYVNRSSQVIKELESCCDNLMSKYSLYFTANSEDPFIDFLKSTKVGGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM5</accession>
    <name>B1KIM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326848.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4265"/>
    <dbReference type="EnsemblBacteria" id="ACA88521">
        <property type="protein sequence ID" value="ACA88521"/>
        <property type="gene ID" value="Swoo_4265"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4265"/>
    <dbReference type="eggNOG" id="ENOG50318ND">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163267_0_0_6"/>
    <dbReference type="OMA" id="CLDQAWR"/>
    <dbReference type="OrthoDB" id="1639231at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="14489" checksum="0F67D6C42824BC3B" modified="2008-04-29" version="1">MCQCFPQFEHQDPAINVLRHKIRHGEEVDNPSLVLIWFSMEEAMASTCKQAAWSLYVAEYRLLLDTLSDDMLAGHWRLWCLDNIYKPLSALSRLVGSDEQKQELEKLFYELRVTSQFFKPGLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ1</accession>
    <name>B1KIQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88547">
        <property type="protein sequence ID" value="ACA88547"/>
        <property type="gene ID" value="Swoo_4292"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4292"/>
    <dbReference type="HOGENOM" id="CLU_1488086_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="20039" checksum="866E537F74922137" modified="2008-04-29" version="1">MAFMLLQPIMSLLFQLPQSLYVFKAIGETFEINSLDSYGREIAIITNLSAIILIYPLKTRKLGLKLAAILFSVAIIGHGIIGVQLPTYGEAVTSSMGMIQTGDHWNAIGEARRNGFSRFEVLLEPSGYTLFVPKGYDKGLSFILYLLALGLTALQLKWHSKVTTPKREKPSPFTDSKSQPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ15</accession>
    <name>B1KJ15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal-transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325371.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2759"/>
    <dbReference type="EnsemblBacteria" id="ACA87035">
        <property type="protein sequence ID" value="ACA87035"/>
        <property type="gene ID" value="Swoo_2759"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2759"/>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_12_3_6"/>
    <dbReference type="OMA" id="YCARLFE"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="80"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="15129" checksum="AB9CBF5F0DEBC7B9" modified="2008-04-29" version="1">MSQRKVVRNSDVMTNKYVMVDGLHTVADAVKHAIEQDVKVLFVNKRHENDEFGIVLMSDIAKQVLAKDKAPERVNIYEIMLKPVFSVNAEMDVRYCARLFERFGISKAPVVENGEILGLVSYQDLVLKGMMAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ67</accession>
    <name>B1KJ67_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325423.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2812"/>
    <dbReference type="EnsemblBacteria" id="ACA87087">
        <property type="protein sequence ID" value="ACA87087"/>
        <property type="gene ID" value="Swoo_2812"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2812"/>
    <dbReference type="eggNOG" id="COG4667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048271_0_0_6"/>
    <dbReference type="OMA" id="DLDWYFD"/>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07208">
        <property type="entry name" value="Pat_hypo_Ecoli_yjju_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045943">
        <property type="entry name" value="DUF6363"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037483">
        <property type="entry name" value="YjjU-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19890">
        <property type="entry name" value="DUF6363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="32"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="36"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="64"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="196"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="38523" checksum="BCBBBF2C5205B940" modified="2008-04-29" version="1">MPSIPFNPIQSQNLSTYGNKQSLSLPLAQTALVAEGGGQRGIFTAGILDAWLENDFNPFQLLIGTSAGAQNLSSFITRQLGFAQTSISNLSRSPQFFNISRSLTGKNTVDLDWYFNQVGTLEQTDKIKQPHKLNTQCGVKKLAQRQLLISTTNISNYQANFFSPSQENWLTLLKASSALPFLYRKGVKLDDTYHVDGGLSAPLPVEEAYKRGARKIVVLRTLPKEYAAHTPWVNRLKSWICSSNQCPKAIDYFVHHEHAYWESLKFIESPPTGVEVIQIFPEQGLKSKILGSRESDLEQDYQLGKLAGTRFIEQHSQTLLTFPSSASLESYKQHRAETTRRYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ73</accession>
    <name>B1KJ73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325429.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2818"/>
    <dbReference type="EnsemblBacteria" id="ACA87093">
        <property type="protein sequence ID" value="ACA87093"/>
        <property type="gene ID" value="Swoo_2818"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2818"/>
    <dbReference type="eggNOG" id="ENOG5030QJ6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1694012_0_0_6"/>
    <dbReference type="OMA" id="REGMAFY"/>
    <dbReference type="OrthoDB" id="1591841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764951" evidence="1">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="152" mass="17138" checksum="A2B487B027701994" modified="2008-04-29" version="1" precursor="true">MKKLILLISCFIAAFSAYAEEVDLKEFGKSYFQAWQATQVPEATTKDVENYLSFLKEDVGHQHLPYASDDSRLPSGKSNMREGMAFYLGAHTAYSATLNQIVPAYNVVVITYSTQSSGIHPQTKEVIHQNYETMEVLEIEDGKVSVIRKYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD5</accession>
    <name>B1KJD5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326933.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4354"/>
    <dbReference type="EnsemblBacteria" id="ACA88607">
        <property type="protein sequence ID" value="ACA88607"/>
        <property type="gene ID" value="Swoo_4354"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4354"/>
    <dbReference type="eggNOG" id="ENOG502Z9NJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074587_1_0_6"/>
    <dbReference type="OMA" id="YIWRGLT"/>
    <dbReference type="OrthoDB" id="1970612at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010239">
        <property type="entry name" value="CHP02001"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09694">
        <property type="entry name" value="Gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02001">
        <property type="entry name" value="gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767123" evidence="1">
        <location>
            <begin position="23"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="24868" checksum="3ACC02025F2AEEF6" modified="2008-04-29" version="1" precursor="true">MKLALSSTLLASSLLTSLYADASVTANIGATSNYLWRGVSQTQDAVAVQGGVDYEHESGLYLGTWASNVDFDDETSYELDFYAGYAGTIGEEFGYDVSYLYYAYPDSDSDIDFGELKAAISWRWFSLSYSHVTNAGSDVATAPWDNEDMGYLDAGVSIPLSDSLSISAHYGYSTGDVVTAWFDTDSYSDYSLSLNKETEIGAVSFTVSDTDLNGDDAKIVIGYSYSFEL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-11-03" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJK9</accession>
    <name>HOA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4-hydroxy-2-oxovalerate aldolase</fullName>
            <shortName evidence="1">HOA</shortName>
            <ecNumber evidence="1">4.1.3.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">4-hydroxy-2-keto-pentanoic acid aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">4-hydroxy-2-oxopentanoate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1390</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:22624"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:73143"/>
            <dbReference type="EC" id="4.1.3.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxy-2-oxovalerate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.39" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324028.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJK9"/>
    <dbReference type="SMR" id="B1KJK9"/>
    <dbReference type="STRING" id="392500.Swoo_1390"/>
    <dbReference type="EnsemblBacteria" id="ACA85682">
        <property type="protein sequence ID" value="ACA85682"/>
        <property type="gene ID" value="Swoo_1390"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1390"/>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049173_0_0_6"/>
    <dbReference type="OMA" id="YVGGQED"/>
    <dbReference type="OrthoDB" id="840579at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008701">
        <property type="term" value="F:4-hydroxy-2-oxovalerate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07943">
        <property type="entry name" value="DRE_TIM_HOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01656">
        <property type="entry name" value="HOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017629">
        <property type="entry name" value="4OH_2_O-val_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012425">
        <property type="entry name" value="DmpG_comm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035685">
        <property type="entry name" value="DRE_TIM_HOA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07836">
        <property type="entry name" value="DmpG_comm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03217">
        <property type="entry name" value="4OH_2_O_val_ald"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000387917" description="4-hydroxy-2-oxovalerate aldolase">
        <location>
            <begin position="1"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="16"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01656"/>
        </source>
    </evidence>
    <sequence length="339" mass="36258" checksum="B8F3478D97863A9F" modified="2008-04-29" version="1">MNISNKKIILHDMCLRDGMHAKRHQISLAEMTQLATALDDAGVPLIEVTHGDGLGGNSVNYGFAAHSDEEYLSTVIPLMKQAKISALLLPGIGTVDHLRMAHELGVSTIRVAAQCTEADVTEQHISLSRQLGLDTVGFLMMAHMLEPKALLEQAKLMESYGANCIYCTDSAGYMLQDDVFERISVLRDGLKPDTQIGFHGHHNLALGVANSLTAVEAGAERIDGSAAGLGAGAGNTPLEVFNAVATRMGASTDVDVFKLMAAAEEIVVPMMDQAIRVDRDSLVLGYAGVYSSFLLHAKRAAEKYGVPSEAILLKLGQMKTVGGQEDMIEDVAINLAKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM3</accession>
    <name>B1KJM3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="4">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">kmo</name>
        <name evidence="6" type="ordered locus">Swoo_1404</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H(+) + L-kynurenine + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324042.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1404"/>
    <dbReference type="EnsemblBacteria" id="ACA85696">
        <property type="protein sequence ID" value="ACA85696"/>
        <property type="gene ID" value="Swoo_1404"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1404"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023210_0_1_6"/>
    <dbReference type="OMA" id="REFMFIA"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="5">
        <location>
            <begin position="8"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="456" mass="52070" checksum="BBFF2D25E9BEA3F6" modified="2008-04-29" version="1">MDKQVKNITVAGAGPVGALLSVMLAKQGYKVDLFESRVDSRKASIYQGKSINLALSDRGWLALQAVGLDDKIREHAIPMYCRVMHDLEGNLTKQPYGKEGQAIWSVSRAGINEQLISLAEEEPLIDVHFEHHLTQLDFDTLNSEFSNKEEDRKQHKTDLLFGADGAFSKVRRLAQELPRQRISYSLEYMPQSYIELTIAPNQDGSHKLEKNALHIWPRKAFMLIALPNNDGSFTCTLFLNHEGELSFQSLDSKEKVTQFFEDNFADALPLLDNPVDEFMQKSASPLCLVHIYPWVVNNKVGLIGDAAHAMVPFYGQGMNCGFEDCRILNELIQTHEHNWEQILTAYQAERKPNGDAIIELAKRNFVEMSDLSGDSNFLLRKKIESEFNRMYPQLWVPLYSMVTFSPHLSYSSALTTGDIQNEIMDEIMQLDNIHQEWQSPHVYQLLHKLVLEKLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJN8</accession>
    <name>B1KJN8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PBPb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324057.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1419"/>
    <dbReference type="EnsemblBacteria" id="ACA85711">
        <property type="protein sequence ID" value="ACA85711"/>
        <property type="gene ID" value="Swoo_1419"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1419"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064076_8_2_6"/>
    <dbReference type="OMA" id="DCYINDR"/>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="29"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="30760" checksum="B3B7AA4E5B677A60" modified="2008-04-29" version="1" precursor="true">MKNIQLIIYVFISLFIPSWLLAAEIGVEVYADDSYPPYSYIENGELKGIYTEILQKAFSRMEGYKVKIKPVPWKRGLSYIENGKGFAIYPPYHRTKERPYMWPYSIPILDERVIVVCRAEVLTRSIRPIWPDDYFGLVIGNNAGFSSGGDRFWEAVKDGKITVNEANGNEKNIMMLGLGRTDCYMNDRISILWELKQLKANGMYDEGGKHARLMEGATISIEQGFLAFTATGADKFPHMDDFILKFNTVIYAMRRSGELQKILDDFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJS2</accession>
    <name>B1KJS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324091.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1457"/>
    <dbReference type="EnsemblBacteria" id="ACA85745">
        <property type="protein sequence ID" value="ACA85745"/>
        <property type="gene ID" value="Swoo_1457"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1457"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001968_0_0_6"/>
    <dbReference type="OMA" id="TRSYVYD"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1423" mass="159062" checksum="E1357121CEBF9095" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK97</accession>
    <name>B1KK97_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dissimilatory sulfite reductase</fullName>
            <ecNumber evidence="1">1.8.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide = [protein]-dithiol + 2 AH2 + H(+) + sulfite</text>
            <dbReference type="Rhea" id="RHEA:51676"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </cofactor>
        <text evidence="1">Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="1">Binds 8 heme c groups covalently per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; sulfite reduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the multiheme cytochrome c family.</text>
    </comment>
    <dbReference type="EC" id="1.8.99.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327054.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4477"/>
    <dbReference type="EnsemblBacteria" id="ACA88728">
        <property type="protein sequence ID" value="ACA88728"/>
        <property type="gene ID" value="Swoo_4477"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4477"/>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_406457_0_0_6"/>
    <dbReference type="OMA" id="DCHEAQA"/>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="UniPathway" id="UPA00370"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016002">
        <property type="term" value="F:sulfite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009061">
        <property type="term" value="P:anaerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02023">
        <property type="entry name" value="Sulfite_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023155">
        <property type="entry name" value="Cyt_c-552/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032897">
        <property type="entry name" value="Sulfite_reductase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13435">
        <property type="entry name" value="Cytochrome_C554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0763">Sulfate respiration</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009007464" description="Dissimilatory sulfite reductase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_C554" evidence="2">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>6</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>6</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>6</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>6</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>8</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>7</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>7</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>7</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>8</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>8</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="561"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>8</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="645"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>7</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="678" mass="75382" checksum="6CBFD589219541D3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK99</accession>
    <name>B1KK99_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c-type biogenesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4479</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Possible subunit of a heme lyase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CcmH/CycL/Ccl2/NrfF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4479"/>
    <dbReference type="EnsemblBacteria" id="ACA88730">
        <property type="protein sequence ID" value="ACA88730"/>
        <property type="gene ID" value="Swoo_4479"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4479"/>
    <dbReference type="eggNOG" id="COG3088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107187_0_2_6"/>
    <dbReference type="OMA" id="ELRCPMS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005616">
        <property type="entry name" value="CcmH/CycL/Ccl2/NrfF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038297">
        <property type="entry name" value="CcmH/CycL/NrfF/Ccl2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03918">
        <property type="entry name" value="CcmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011021590" description="Cytochrome c-type biogenesis protein" evidence="5">
        <location>
            <begin position="30"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="149" mass="16794" checksum="BCB961CC997F0F15" modified="2008-04-29" version="1" precursor="true">MNRAILNMSKLSVWLTVILLFSTSLTASAVTDKIDYTHDQIRDLGFEIAHELRCPMSVNQNLFDSGAPIASELKGQIFLMLEQGESKQAIIDFLVQRYGEKIRYQPSLSMATAALWFGPILLLFGIIGFAALLIREQRKHQDTNGNTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH1</accession>
    <name>B1KKH1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer membrane protein assembly factor BamE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bamE</name>
        <name evidence="7" type="ordered locus">Swoo_1523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BamE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324157.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1523"/>
    <dbReference type="EnsemblBacteria" id="ACA85811">
        <property type="protein sequence ID" value="ACA85811"/>
        <property type="gene ID" value="Swoo_1523"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1523"/>
    <dbReference type="eggNOG" id="COG2913">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083835_2_2_6"/>
    <dbReference type="OMA" id="LLTDTFH"/>
    <dbReference type="OrthoDB" id="1813418at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00925">
        <property type="entry name" value="OM_assembly_BamE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026592">
        <property type="entry name" value="BamE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037873">
        <property type="entry name" value="BamE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007450">
        <property type="entry name" value="Lipoprotein_SmpA/OmlA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37482">
        <property type="entry name" value="PTHR37482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04355">
        <property type="entry name" value="SmpA_OmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SmpA_OmlA" evidence="6">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="167" mass="19224" checksum="D0EB0FD6D8066286" modified="2008-04-29" version="1" precursor="true">MTIKKKSLTLLGAAALSLSMTGCGVFDWLIYKPDIPQGNYMETQQVEKLRVEMTKEQVEYILGRPVLRDSFADDTWYYVYHYKSGRDASITHKELIIHFDNDQLTKVVGDYELSEEFNTPLEQSRLPDAPLIEEVEQIDPLIPEQRPDAKPLVEENDPEAQASKKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH5</accession>
    <name>B1KKH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324161.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1527"/>
    <dbReference type="EnsemblBacteria" id="ACA85815">
        <property type="protein sequence ID" value="ACA85815"/>
        <property type="gene ID" value="Swoo_1527"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1527"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022176_2_1_6"/>
    <dbReference type="OMA" id="RYCAIAN"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="508"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="642" mass="73770" checksum="8B0F8FAAF901C7F8" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKK6</accession>
    <name>B1KKK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325559.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2950"/>
    <dbReference type="EnsemblBacteria" id="ACA87223">
        <property type="protein sequence ID" value="ACA87223"/>
        <property type="gene ID" value="Swoo_2950"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2950"/>
    <dbReference type="eggNOG" id="COG2080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052511_3_0_6"/>
    <dbReference type="OMA" id="EHDVPQC"/>
    <dbReference type="OrthoDB" id="1819473at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="157" mass="16930" checksum="E856C624EA40A33A" modified="2008-04-29" version="1" precursor="true">MSDNELKLNINGKQFTLDADPNMPILWAVRDMLGMTGTKYGCGAGLCGACTIHIDGEPARACLTNLKQVQGKSVTTIEGLEADKLRRAWSEHNVPQCGYCQSGQLMSAAALLSKKQRPSETEIDDAMSGNICRCGTYNRIKSAILSAAESSKMEAEL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL24</accession>
    <name>TDH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">L-threonine 3-dehydrogenase</fullName>
            <shortName evidence="1">TDH</shortName>
            <ecNumber evidence="1">1.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tdh</name>
        <name type="ordered locus">Swoo_0064</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:13161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="1.1.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.103" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322714.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL24"/>
    <dbReference type="SMR" id="B1KL24"/>
    <dbReference type="STRING" id="392500.Swoo_0064"/>
    <dbReference type="EnsemblBacteria" id="ACA84365">
        <property type="protein sequence ID" value="ACA84365"/>
        <property type="gene ID" value="Swoo_0064"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0064"/>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_0_6"/>
    <dbReference type="OMA" id="ETWYAMS"/>
    <dbReference type="OrthoDB" id="972769at2"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00627">
        <property type="entry name" value="Thr_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004627">
        <property type="entry name" value="L-Threonine_3-DHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00692">
        <property type="entry name" value="tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000130566" description="L-threonine 3-dehydrogenase">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="286"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00627"/>
        </source>
    </evidence>
    <sequence length="341" mass="37266" checksum="CEE2538A035C267A" modified="2008-04-29" version="1">MKALSKLKPEEGIWMVDAPKPEMGHNDLLIKIRKTAICGTDVHIYNWDEWSQNTIPVPMVVGHEYVGEVVDIGQEVRGFSIGDRVSGEGHITCGHCRNCRAGRTHLCRNTSGVGVNRDGAFAEYLVIPAFNAFKIPDDISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVCRHVGARHVVITDVNEYRLELAQKMGATRAVNVAKEDLKDVMSELGMTEGFDVGLEMSGVPSAFHSMLDTMNHGGKVAMLGIPGGDMAIDWSKVIFKGLIIKGIYGREMFETWYKMASLIQSGLDISPIITHHYKVDEFQQGFDAMRSGQSGKVILNWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL50</accession>
    <name>B1KL50_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322740.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0090"/>
    <dbReference type="EnsemblBacteria" id="ACA84391">
        <property type="protein sequence ID" value="ACA84391"/>
        <property type="gene ID" value="Swoo_0090"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0090"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127573_0_0_6"/>
    <dbReference type="OMA" id="IRNQYLI"/>
    <dbReference type="OrthoDB" id="1826274at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17795" checksum="C485467025B47E71" modified="2008-04-29" version="1">MYQVEIVQATIVTPELLQSLMELNQAIPEFDNAYPMTEYQTRLSDKPMLALFIKVEGEVAGFKLGYERDNGQFYSWLGGILPEFRGLGLAKQLLQTQERWAKEQGYHQIEVKTLNRFTSMLKMLISNQYQITNLKQDTDKLELNKISLQKSLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL53</accession>
    <name>B1KL53_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isochorismate synthase MenF</fullName>
            <ecNumber evidence="4">5.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Isochorismate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menF</name>
        <name evidence="6" type="ordered locus">Swoo_0093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of chorismate to isochorismate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>chorismate = isochorismate</text>
            <dbReference type="Rhea" id="RHEA:18985"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="EC" id="5.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 1/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the isochorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.4.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322743.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0093"/>
    <dbReference type="EnsemblBacteria" id="ACA84394">
        <property type="protein sequence ID" value="ACA84394"/>
        <property type="gene ID" value="Swoo_0093"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0093"/>
    <dbReference type="eggNOG" id="COG1169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006493_8_4_6"/>
    <dbReference type="OMA" id="TGHGQSI"/>
    <dbReference type="OrthoDB" id="1469584at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00163"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008909">
        <property type="term" value="F:isochorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01935">
        <property type="entry name" value="MenF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004561">
        <property type="entry name" value="IsoChor_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034681">
        <property type="entry name" value="MenF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044250">
        <property type="entry name" value="MenF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47253">
        <property type="entry name" value="PTHR47253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00543">
        <property type="entry name" value="isochor_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="5">
        <location>
            <begin position="190"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="452" mass="51270" checksum="5316A209917D2CCD" modified="2008-04-29" version="1">MAVYSLSQAIASLTDTLKQLKFQTQSDPIIQLSVSIKPVPAIAWLAAQPCYPRIYWKGRDTEEEVAAIGCCKDFFYADNIDDNQLSIEYQKQRALSNNQDIRYYGGVAFDRTTECWPEFGRAHFVLPRVELRRHGNDYKLLVNLNCETGNAESERDQAMTSLAQLASPKPLPPPNKINILSRSDRPDRYRWTELVNQVTHQKFIQETPKVVLSRLTQLEINQPVDPWMLLACWQGRNKNSFQFGFQFSPDSTFISCTPERLYRRRQRELFTEALAGTTTRGLNLEEDKVLAQTLMEDNKNSHENRLVKDHIVDALTPLSNYVGAESIPKVFKLSHIQHLHRSIRAELKPGVDDFQLLQALHPTPAVGGLPKEPAMSFIRQSEGYARGWYAGACGYFNKYESEFAVAIRSALIEPGRINLFAGAGIVSGSEADSEWIELENKLTTILSILTEL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB9</accession>
    <name>EX7L_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="1">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="1">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">xseA</name>
        <name type="ordered locus">Swoo_1558</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the XseA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324190.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLB9"/>
    <dbReference type="SMR" id="B1KLB9"/>
    <dbReference type="STRING" id="392500.Swoo_1558"/>
    <dbReference type="EnsemblBacteria" id="ACA85844">
        <property type="protein sequence ID" value="ACA85844"/>
        <property type="gene ID" value="Swoo_1558"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1558"/>
    <dbReference type="eggNOG" id="COG1570">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023625_3_1_6"/>
    <dbReference type="OMA" id="WPAVRFE"/>
    <dbReference type="OrthoDB" id="1371775at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0269">Exonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000122088" description="Exodeoxyribonuclease 7 large subunit">
        <location>
            <begin position="1"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <sequence length="442" mass="49163" checksum="F2194E430BFF6650" modified="2008-04-29" version="1">MKMPKNNVYTVSQLNGEVRQLLEGELGRVWLNAEISNFSSPSSGHWYLTLKDHFAQIRCAMFKGKNRTVTFRPANGQQVLVKGSISVYEPRGDYQLIIESMLPAGDGMLAQQYEALKMKLAAEGLFATDTKRPLPTNINKIGVITSATGAALKDVLHVLARRDPSIEVVVYPTQVQGDNAAKLICRAIELANARQEVDVLLLTRGGGSLEDLWCFNSEDLAHCIYNSALPVVSAVGHEVDTSISDYVADVRAPTPSAGAELLSKDADDKAHKLIAGLSRLKQSWQHYQLKTVQKATALENRLQRQDPKRRLEQFEQSFDEMQLRLNAALNSRIHKLALKQQNLSHRLSQQSPEHRLTLEAKRLDYLTTRLNEGIKDKLHDVELSLKNSAHQLQTVSPLATLSRGYSITQDESGKVLLNAKDAKTGDLLTTRLLEGELRSKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC6</accession>
    <name>B1KLC6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome bd ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_1565</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324197.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1565"/>
    <dbReference type="EnsemblBacteria" id="ACA85851">
        <property type="protein sequence ID" value="ACA85851"/>
        <property type="gene ID" value="Swoo_1565"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1565"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_0_1_6"/>
    <dbReference type="OMA" id="FLINIAM"/>
    <dbReference type="OrthoDB" id="271551at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="518" mass="58201" checksum="E5259D7383770A20" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC9</accession>
    <name>B1KLC9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1568</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324200.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1568"/>
    <dbReference type="EnsemblBacteria" id="ACA85854">
        <property type="protein sequence ID" value="ACA85854"/>
        <property type="gene ID" value="Swoo_1568"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1568"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_19_6"/>
    <dbReference type="OMA" id="GLFEKRF"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033462">
        <property type="entry name" value="Cache_3-Cache_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17201">
        <property type="entry name" value="Cache_3-Cache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="338"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="395"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="667" mass="72605" checksum="42C9EFDA4F10F0DA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG3</accession>
    <name>B1KLG3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Flagellar basal-body rod protein FlgG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Distal rod protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1602</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5 7">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324234.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1602"/>
    <dbReference type="EnsemblBacteria" id="ACA85888">
        <property type="protein sequence ID" value="ACA85888"/>
        <property type="gene ID" value="Swoo_1602"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1602"/>
    <dbReference type="eggNOG" id="COG4786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013687_0_1_6"/>
    <dbReference type="OMA" id="TRDGTFH"/>
    <dbReference type="OrthoDB" id="1488472at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009426">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012834">
        <property type="entry name" value="FlgG_G_neg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02488">
        <property type="entry name" value="flgG_G_neg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="8">
        <location>
            <begin position="10"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="9">
        <location>
            <begin position="184"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="27465" checksum="0A4BEFABDD3D5585" modified="2008-04-29" version="1">MHPALWISKTGLDAQQTDISVISNNVANASTVGYKKSRAVFEDLLYQTVNQAGGVSASNTKLPNGLNVGAGTKVVATQKVFTQGNMLTTDNSLDLMVEGPGFFEIQLPDGTAAYTRNGQFTLDDTGQIVTSGSGYVVQPAITIPENATGITVSAEGEVSVKTAGTAESQVVGQLTMSDFINPSGLDPMGQNLYTETGASGTPIQGTASLDGMGAVRQGALETSNVNVTEELVNLIESQRIYEMNSKVISAVDQMLSYVNQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLL0</accession>
    <name>B1KLL0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sodium/proline symporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Proline permease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3036</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the sodium-dependent uptake of extracellular L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28967"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3036"/>
    <dbReference type="EnsemblBacteria" id="ACA87307">
        <property type="protein sequence ID" value="ACA87307"/>
        <property type="gene ID" value="Swoo_3036"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3036"/>
    <dbReference type="eggNOG" id="COG0591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_2_6"/>
    <dbReference type="OMA" id="CWTDLIQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005298">
        <property type="term" value="F:proline:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031402">
        <property type="term" value="F:sodium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015824">
        <property type="term" value="P:proline transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11475">
        <property type="entry name" value="SLC5sbd_PutP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011851">
        <property type="entry name" value="Na/Pro_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02121">
        <property type="entry name" value="Na_Pro_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0915">Sodium</keyword>
    <keyword evidence="7 10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 10" id="KW-0769">Symport</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="425"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="488" mass="52616" checksum="866806DFFFB49110" modified="2008-04-29" version="1">MNGNSMSIELPVLITFIGYLSLMMGIGLWAYKATDSVDDYILGGRGMGPAVTALSVGASDMSGWLLLGLPGAVYLGGLGEAWIGIGLVFGAWLNWLFVAKRLRIYTEFTDNALTLPDFFEKRFEDNKGLLKLVSAITILIFFTFYASSGMVGGAILFEKVFGLDYTLALIIGSTIIVAYTFVGGFFAVSWTDFFQGCLMLVALLIVPVAIFSQPETQNGLDSLDPSMLALFHENTTFIGLISLLAWGLGYFGQPHILSRFMAINSPDDIKVSRRIAMSWMLVALIGALATGIAGSLYFASEPLANPETVFIHLAHAAFNPWIGGLLIAAILSAIMSTIDSQLLVCSSVITEDFYKKWLRPEASSKELMLVGRIGVLVIAVIAGIVALNPESSVLGLVSYAWAGFGAAFGPVVLLALFWKDYSRNGAIATILVGAITVVIWKQLSGGIFDLYEILPGFIFATLIGVIVSRFSAPSDATKEQFRVFTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ5</accession>
    <name>B1KLQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325688.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3081"/>
    <dbReference type="EnsemblBacteria" id="ACA87352">
        <property type="protein sequence ID" value="ACA87352"/>
        <property type="gene ID" value="Swoo_3081"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3081"/>
    <dbReference type="eggNOG" id="ENOG5032FKC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2540728_0_0_6"/>
    <dbReference type="OMA" id="NRKTKVC"/>
    <dbReference type="OrthoDB" id="2081411at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="9884" checksum="11C8BEDEA62B855E" modified="2008-04-29" version="1">MRYCLVLAFFVLAGCESSQEMFKSQGAEGQLVDAGIRCEMMARTGSNRKTKVCRTVEQIKKDEQEAYSSLNRKQRTGYTIPKEGGLPK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLT9</accession>
    <name>FOLD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="1">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="1">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">folD</name>
        <name type="ordered locus">Swoo_3115</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="1"/>
    <dbReference type="EC" id="3.5.4.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325722.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLT9"/>
    <dbReference type="SMR" id="B1KLT9"/>
    <dbReference type="STRING" id="392500.Swoo_3115"/>
    <dbReference type="EnsemblBacteria" id="ACA87386">
        <property type="protein sequence ID" value="ACA87386"/>
        <property type="gene ID" value="Swoo_3115"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3115"/>
    <dbReference type="eggNOG" id="COG0190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034045_2_1_6"/>
    <dbReference type="OMA" id="HIVGRPM"/>
    <dbReference type="OrthoDB" id="1449514at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0486">Methionine biosynthesis</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0554">One-carbon metabolism</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000196804" description="Bifunctional protein FolD">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="166"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <sequence length="286" mass="30820" checksum="45F2D9517F65F9E6" modified="2008-04-29" version="1">MTAQTIDGKAIAQSIRTQLKEKVTARKEAGKRVPGLAVILVGADPASQVYVGSKRRACEEVGFLSRSYDLESSTTEEQLLSLIDECNQDPAIDGILVQLPLPEHIEESKVIERIRPDKDVDGFHPYNVGRLAQRIPVLRSCTPMGIMTLIKSTGVDTYGLDALVVGASNIVGRPMSLELLLAGCTTTTCHRFTRNLEQKVRQADLVVVAVGKPGFIPGEWIKPGALVIDVGINRLEDGSLVGDVQYDVAAQNASFITPVPGGVGPMTIASLLENTLYAAEQYHDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV8</accession>
    <name>B1KLV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Na+/Ca+ antiporter, CaCA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4588</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327163.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4588"/>
    <dbReference type="EnsemblBacteria" id="ACA88838">
        <property type="protein sequence ID" value="ACA88838"/>
        <property type="gene ID" value="Swoo_4588"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4588"/>
    <dbReference type="eggNOG" id="COG0530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007948_0_3_6"/>
    <dbReference type="OMA" id="WHQSRHY"/>
    <dbReference type="OrthoDB" id="804531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="165"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="310" mass="32214" checksum="E06F9CA27DC37B5A" modified="2008-04-29" version="1" precursor="true">MLILLAIVGGFVILTLGAEALVRGASAIALRLGIAPLIIGLTIVAFGTSAPELAVSLKSAIAGNSGIALGNVIGSNIANIGLILAITALIRPIQVQSQMVKRDIPIMIAASMLFWGLLLDGQLSFWDGALLTTLLVCYLSFSYFSSKNSNDGEELDTSPQHPMLSVLFIIAGISMLVGGGILFVDGAVDLAKTFGISEVIIGLTIVAIGTSMPELVTSIVAARKGESDIAIGNIVGSNLFNILGILGITALIHPIAAAGIQDFDLLVMLLLALIVLPFAWTGFRIGRREGGILLLGYLSYISYLVVQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW1</accession>
    <name>B1KLW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4591</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327166.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4591"/>
    <dbReference type="EnsemblBacteria" id="ACA88841">
        <property type="protein sequence ID" value="ACA88841"/>
        <property type="gene ID" value="Swoo_4591"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4591"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_6"/>
    <dbReference type="OMA" id="DDPMMQL"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="198" mass="21466" checksum="9E1562299158C0A8" modified="2008-04-29" version="1">MRILLAEDQAMVRGALAALLSLDGEFEVIQACDGDQALSLLKAQTFDLLLTDIEMPGFTGLELAQWCQQQNSTIKVIILTTFGRAGYIKRAIEYGAGGFLLKDAPSESLIQGIKQVMAGKRVIDPELAIMAVGENDPLSDKERKALRLASEGKTTSEIAALLFIAEGTVRNYLSEATSKLHGSNRIDAARIAKQKGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM37</accession>
    <name>B1KM37_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0149</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322799.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0149"/>
    <dbReference type="EnsemblBacteria" id="ACA84450">
        <property type="protein sequence ID" value="ACA84450"/>
        <property type="gene ID" value="Swoo_0149"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0149"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_27_6"/>
    <dbReference type="OMA" id="WIRPPQA"/>
    <dbReference type="OrthoDB" id="1031685at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="178"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="238"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="436" mass="48993" checksum="4B830D58CA598A95" modified="2008-04-29" version="1" precursor="true">MKWLKKILPRSSFSQTVMLIGSLLLINQLVSYLSVATYFIQPTYQQINQLIARQVKLLFVDGVDVGREHLTMVDALNAKVRGDGMKIYNQKQARAAGIEQTTYYGFLSSQMSEHLGGKAEVRIAQGDDFEIWIRPPQAPSIWIKVPLTGFNEYDLSPLTLYLMVIGALSVAGGWWFARQQNRPLKRLQKAAILVSMGDYPKPLPLNGSTEIVEVTNAFNQMSHSMKQLEQDRALLMAGISHDLRTPLTRIRLASEMMVEEDEYLKDGIVHDIEDMDAIINQFIAYIRQDQESTREQEQINYLIQDVVQAESNREGKIEVELATCPDIPMQGIAIKRILSNLVENAFRYGQGWVKLSSHFDGKRVGFSVEDNGPGIPEDQIPELFQPFTQGDIARGSVGSGLGLAIIKRIVDRHQGEVILTNRAEGGLHAQVWLPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM65</accession>
    <name>B1KM65_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase subunit 1</fullName>
            <ecNumber evidence="8">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0177</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322827.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0177"/>
    <dbReference type="EnsemblBacteria" id="ACA84478">
        <property type="protein sequence ID" value="ACA84478"/>
        <property type="gene ID" value="Swoo_0177"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0177"/>
    <dbReference type="eggNOG" id="COG0843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011899_7_3_6"/>
    <dbReference type="OMA" id="PVDFQYH"/>
    <dbReference type="OrthoDB" id="316745at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01663">
        <property type="entry name" value="Cyt_c_Oxidase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033944">
        <property type="entry name" value="Cyt_c_oxase_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014241">
        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02891">
        <property type="entry name" value="CtaD_CoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="10">
        <location>
            <begin position="36"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="540" mass="60565" checksum="BD87C30C77CEA017" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM68</accession>
    <name>LEXA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LexA repressor</fullName>
            <ecNumber evidence="1">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lexA</name>
        <name type="ordered locus">Swoo_0180</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S24 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322830.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KM68"/>
    <dbReference type="SMR" id="B1KM68"/>
    <dbReference type="STRING" id="392500.Swoo_0180"/>
    <dbReference type="MEROPS" id="S24.001"/>
    <dbReference type="EnsemblBacteria" id="ACA84481">
        <property type="protein sequence ID" value="ACA84481"/>
        <property type="gene ID" value="Swoo_0180"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0180"/>
    <dbReference type="eggNOG" id="COG1974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_45_3_6"/>
    <dbReference type="OMA" id="HVWLLPH"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000089598" description="LexA repressor">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="1">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="1">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <sequence length="205" mass="22549" checksum="E2507A44A843B498" modified="2008-04-29" version="1">MRPLTPRQAEILELIKCNIAETGMPPTRAEIAKRLGFKSANAAEEHLKALAKKGCIEIIPGTSRGIRLAQTEELEEQGLPLIGQVAAGEPILAQEHVEQHYQVDPNMFHPSADFLLRVRGDSMKDIGILEGDLLAVHKAEQARNGQVVVARVEDDVTVKRFEKKGSTVYLHAENEDYSPIVVDLTNQSLSIEGLAVGVIRNGDWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM93</accession>
    <name>B1KM93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84506">
        <property type="protein sequence ID" value="ACA84506"/>
        <property type="gene ID" value="Swoo_0205"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0205"/>
    <dbReference type="HOGENOM" id="CLU_2652463_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="76" mass="8695" checksum="D6E50DA2F788AAD5" modified="2008-04-29" version="1">MFPTFIGIPYIQVKAMVDDVPYIISTFPPSVEVKGVCAWNIYADSPRMDSYQLCTCLQNIYPFVPKLETRNSKLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMU7</accession>
    <name>B1KMU7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325811.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3205"/>
    <dbReference type="EnsemblBacteria" id="ACA87475">
        <property type="protein sequence ID" value="ACA87475"/>
        <property type="gene ID" value="Swoo_3205"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3205"/>
    <dbReference type="eggNOG" id="COG3126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130974_1_1_6"/>
    <dbReference type="OMA" id="QFEAGHT"/>
    <dbReference type="OrthoDB" id="1992770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039366">
        <property type="entry name" value="Pilotin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09619">
        <property type="entry name" value="YscW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767504" evidence="1">
        <location>
            <begin position="26"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="15500" checksum="1C1C92656ADAC5CF" modified="2008-04-29" version="1" precursor="true">MKKWFKSVSSIALGARLMMVGVISAGMLTGCATPNAGVEIQGEVWFKERIALPQEAVLTVQIKDVSLMDAPAVVIAEIERDNVTTPAPFQFVINRDQFEQGNTYAVGANISLNGKLMFINTQAYQIDLGSSEPMSVLVQKVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV7</accession>
    <name>B1KMV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325821.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3215"/>
    <dbReference type="EnsemblBacteria" id="ACA87485">
        <property type="protein sequence ID" value="ACA87485"/>
        <property type="gene ID" value="Swoo_3215"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3215"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056366_0_0_6"/>
    <dbReference type="OMA" id="DCMHYLG"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="69"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="278" mass="30506" checksum="A450A42015FA14ED" modified="2008-04-29" version="1">MATDNLVSQHYTHGELLSAIQAALSKQGNSIDKLTLADIAPVDEFHIGGRLATEHLLSQVNFSAEQDILDVGCGLGGAARFIANHFNNQVTGIDLTAEYIETGNVLSQWVGLDERVSLYHGSALSMPFEDSQFHGATQFHVGMNIKDKQTLFREIYRVLKPGSTFALYDIMRMESGALAYPVPWATEASYSHLSTVDEYQAALIQAGFIVGDINERREFGLEFFSKMKERNQAQGGPPPLGLHTLMGAHTAVKVDNMLKNIRGGYIAPVELIAYKSTD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX8</accession>
    <name>RL22_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplV</name>
        <name type="ordered locus">Swoo_4685</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="1">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012144645.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMX8"/>
    <dbReference type="SMR" id="B1KMX8"/>
    <dbReference type="STRING" id="392500.Swoo_4685"/>
    <dbReference type="PRIDE" id="B1KMX8"/>
    <dbReference type="EnsemblBacteria" id="ACA88935">
        <property type="protein sequence ID" value="ACA88935"/>
        <property type="gene ID" value="Swoo_4685"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4685"/>
    <dbReference type="eggNOG" id="COG0091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083987_3_3_6"/>
    <dbReference type="OMA" id="KRIQPRA"/>
    <dbReference type="OrthoDB" id="1666043at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142310" description="50S ribosomal protein L22">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <sequence length="110" mass="12151" checksum="7F9EDC47A621EADB" modified="2008-04-29" version="1">MEVLAKHRFARTSPQKCRLVADQIRGLPVAKALEILTFSPKKAAVLVKKVLDSAIANAEHNEGADIDELRVGAIMIDEGPTMKRIMPRAKGRADRIIKRTSHITVVVSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF9</accession>
    <name>B1KNF9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1751</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324382.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1751"/>
    <dbReference type="EnsemblBacteria" id="ACA86036">
        <property type="protein sequence ID" value="ACA86036"/>
        <property type="gene ID" value="Swoo_1751"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1751"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_11_1_6"/>
    <dbReference type="OMA" id="QFEHREV"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="22"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="24836" checksum="AE95DC98528BE4F2" modified="2008-04-29" version="1">MQIFTYTPPSIPWLDIRYQDRDMIVINKPSGLLSNPGRAENTFDCALTRLLQRYPETILVHRLDCATSGIMVFALNKKAESNIKTQFQNRLSKKTYIAEVQGHLDKTEGVIELAMKADSERPPLQKIAEDGKPSKTYYKVLEKRENSTLVELNPVTGRTHQLRLHMLAIGHPILGDDFYGEQEVIDASHRLCLHAMTLAITHPYSGKLMSFTSLHPFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP6</accession>
    <name>B1KNP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325840.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3234"/>
    <dbReference type="EnsemblBacteria" id="ACA87504">
        <property type="protein sequence ID" value="ACA87504"/>
        <property type="gene ID" value="Swoo_3234"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3234"/>
    <dbReference type="eggNOG" id="COG1757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018751_1_0_6"/>
    <dbReference type="OMA" id="YGDHTSP"/>
    <dbReference type="OrthoDB" id="776648at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="165"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="524" mass="55632" checksum="8A61ED57782CF8F7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU0</accession>
    <name>RRF_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-recycling factor</fullName>
            <shortName evidence="1">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">frr</name>
        <name type="ordered locus">Swoo_3278</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325884.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNU0"/>
    <dbReference type="SMR" id="B1KNU0"/>
    <dbReference type="STRING" id="392500.Swoo_3278"/>
    <dbReference type="EnsemblBacteria" id="ACA87548">
        <property type="protein sequence ID" value="ACA87548"/>
        <property type="gene ID" value="Swoo_3278"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3278"/>
    <dbReference type="eggNOG" id="COG0233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073981_2_1_6"/>
    <dbReference type="OMA" id="FNPMNNG"/>
    <dbReference type="OrthoDB" id="1674344at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000090786" description="Ribosome-recycling factor">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <sequence length="185" mass="20574" checksum="53E10769A52E54CD" modified="2008-04-29" version="1">MLNEIKKDAQDRMDKCVEATKTQMAKVRTGRAHPSLLDSIKVPYYGSLTPLKQVGNVSIEDSRTLAISVFDSTMIPAVEKAIMSSDLGLNPMSAGATIRVPLPALTEERRKDLIKVVRAEAENGRIAVRNVRRDANSDVKALEKEKECTEDDVHRSEDEVQKFTDAHIKLIDEILAAKEAELMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNV6</accession>
    <name>B1KNV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325900.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3294"/>
    <dbReference type="EnsemblBacteria" id="ACA87564">
        <property type="protein sequence ID" value="ACA87564"/>
        <property type="gene ID" value="Swoo_3294"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3294"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091684_0_0_6"/>
    <dbReference type="OMA" id="WAWRLRM"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="215" mass="24121" checksum="8153456D5B4BD902" modified="2008-04-29" version="1">MTKADSAVSQAYRAVYLTAEDLRVAASILYNAYHDDPFFIDSLYAGDMSMYEQKLRGAIREELNELWQQEQALIGLFDADRMVGVACIVTQQVPLGESRYWHWRLKMLISTGWQSTQALIKKESSLLEHLPSPHCGILQFIAVSPTEQGKGLGAQLVQAALSWCDEQPELDGIGVFASDQNHALLFSQHGFTLLEQLSIGKVEGELLFYRGHENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP57</accession>
    <name>B1KP57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, histidine utilization repressor, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327405.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4839"/>
    <dbReference type="EnsemblBacteria" id="ACA89088">
        <property type="protein sequence ID" value="ACA89088"/>
        <property type="gene ID" value="Swoo_4839"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4839"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_0_0_6"/>
    <dbReference type="OMA" id="LDMREGQ"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006547">
        <property type="term" value="P:histidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010248">
        <property type="entry name" value="His_ut_repres"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02018">
        <property type="entry name" value="his_ut_repres"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="233" mass="26086" checksum="E5E692C7B6774D84" modified="2008-04-29" version="1">MATPKFAEIKQYILARIESGEWEEHTRVPSENQLAEQFECSRMTARRGLTELVESGVLERTQGLGTFVAELKSQSSMMAIRNIADEIKDRGHGYSVKQLELTSIEAIAPIAIALGLEAGSQVYYSVLVHCEDGVPLQLEERFVNPKLVPEYLAQDFTTQTPHEYLSQVAPLTEARHTLEAVVANQHNQQALSIEATEPCLQILRRTWSRQGVVSFAKLIHPGSRFRLGGHLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP59</accession>
    <name>B1KP59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327407.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89090">
        <property type="protein sequence ID" value="ACA89090"/>
        <property type="gene ID" value="Swoo_4841"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4841"/>
    <dbReference type="eggNOG" id="ENOG5031FQB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1814505_0_0_6"/>
    <dbReference type="OMA" id="MKYLPAF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="141" mass="15683" checksum="FBD27A07FE33217A" modified="2008-04-29" version="1" precursor="true">MKLVRYLPALAIGFLLAQMILTLFGLASSYILGYLSAAADLNENGIQYLWLILHDVSLVFILSASVYFGYRKFLSQLPDDLFSAILMQLPIAYQCLYLLRPAYDFSSLASSASTISSLTASISVLLIYYICKGHRTSFKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP65</accession>
    <name>B1KP65_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Penicillin-binding protein 1A</fullName>
            <ecNumber evidence="8">2.4.1.129</ecNumber>
            <ecNumber evidence="7">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ordered locus">Swoo_0334</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="8"/>
    <dbReference type="EC" id="3.4.16.4" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322984.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0334"/>
    <dbReference type="CAZy" id="GT51">
        <property type="family name" value="Glycosyltransferase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84635">
        <property type="protein sequence ID" value="ACA84635"/>
        <property type="gene ID" value="Swoo_0334"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0334"/>
    <dbReference type="eggNOG" id="COG5009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006354_2_4_6"/>
    <dbReference type="OMA" id="LAQMAMI"/>
    <dbReference type="OrthoDB" id="652304at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031376">
        <property type="entry name" value="PCB_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17092">
        <property type="entry name" value="PCB_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="12 22" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="22" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Transgly" evidence="20">
        <location>
            <begin position="55"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="PCB_OB" evidence="21">
        <location>
            <begin position="317"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="19">
        <location>
            <begin position="427"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="819"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="833"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00018638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF17092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ACA84635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="847" mass="93550" checksum="24BAF841617EB33E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT7</accession>
    <name>PYRG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CTP synthase</fullName>
            <ecNumber evidence="1">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="1">CTP synthetase</shortName>
            <shortName evidence="1">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrG</name>
        <name type="ordered locus">Swoo_3351</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTP synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325955.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPT7"/>
    <dbReference type="SMR" id="B1KPT7"/>
    <dbReference type="STRING" id="392500.Swoo_3351"/>
    <dbReference type="EnsemblBacteria" id="ACA87620">
        <property type="protein sequence ID" value="ACA87620"/>
        <property type="gene ID" value="Swoo_3351"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3351"/>
    <dbReference type="eggNOG" id="COG0504">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011675_5_0_6"/>
    <dbReference type="OMA" id="EFNNAYR"/>
    <dbReference type="OrthoDB" id="783657at2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000139578" description="CTP synthase">
        <location>
            <begin position="1"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-1" evidence="1">
        <location>
            <begin position="291"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="1">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="1">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="515"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="239"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="380"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <sequence length="545" mass="59983" checksum="BB2BD68BAEC0FC1F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ23</accession>
    <name>B1KQ23_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2061 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327453.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4887"/>
    <dbReference type="EnsemblBacteria" id="ACA89136">
        <property type="protein sequence ID" value="ACA89136"/>
        <property type="gene ID" value="Swoo_4887"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4887"/>
    <dbReference type="eggNOG" id="COG3205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160691_2_2_6"/>
    <dbReference type="OMA" id="FHEKVWK"/>
    <dbReference type="OrthoDB" id="1574819at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018638">
        <property type="entry name" value="DUF2061_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09834">
        <property type="entry name" value="DUF2061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2061" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="64" mass="7118" checksum="3FF5A51FD547588B" modified="2008-04-29" version="1" precursor="true">MTKTLTFAILHFSVAFTITYLLTGSIVIGGAVALIEPSVNTVVFYFHEKVWKRLEKNSNNTITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD6</accession>
    <name>B1KQD6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kelch repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0493"/>
    <dbReference type="EnsemblBacteria" id="ACA84791">
        <property type="protein sequence ID" value="ACA84791"/>
        <property type="gene ID" value="Swoo_0493"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0493"/>
    <dbReference type="eggNOG" id="COG3055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_657037_0_0_6"/>
    <dbReference type="OMA" id="WHNDGNV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765123" evidence="1">
        <location>
            <begin position="24"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="41926" checksum="535EED529600832B" modified="2008-04-29" version="1" precursor="true">MNKLNAVLLLLFPLLLSHFQVSANSPAVHYPNLPEPVANNAVALATSDGEDYLFSFMGLNSEKDHQGVHNRAWRLKLNEPKAQWQAITNVPHIEQLPGRLASMAVGIKDKVYIFGGYTVSKDHQEVSTSDNYLYSLKNNSYSRISDMPVAVDDTAALSYQDRYIYLFGGWHQHGNVNLVQVYDTQTNIWSQATPIPAPAVFGQAVAAVGQELVLCDGVTVQARENQARTFTASPICLYGKIKADNHLKIDWQALPHYSLDSSFQETSKAKPLVAHYRMAATGDSKNQQLIFMAGSDNPYNYNGIGYNSQPSEPSNKLYRFDLKSHSWLPTIEAEQKSMDHRGLILYQGELLRVGGMLEKQLVSDRVLITPINDLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI5</accession>
    <name>B1KQI5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inner membrane protein YccF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324570.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86224">
        <property type="protein sequence ID" value="ACA86224"/>
        <property type="gene ID" value="Swoo_1940"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1940"/>
    <dbReference type="eggNOG" id="COG3304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120384_0_0_6"/>
    <dbReference type="OMA" id="GVYALWP"/>
    <dbReference type="OrthoDB" id="1806532at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031308">
        <property type="entry name" value="UCP028777"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005185">
        <property type="entry name" value="YccF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03733">
        <property type="entry name" value="YccF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028777">
        <property type="entry name" value="UCP028777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="7"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="79"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR028777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="14764" checksum="6D64F8CCCD04CB6B" modified="2008-04-29" version="1">MAVLRLIFNIAWFVLGGFVMGLAWWVAGLLCYISIIGIPFGRACFVIGEMTFWPFGQDHMNRQSLTGREDIGTGAFGTIGNIIWFLLFGIWLAIGHITHALACFVTIIGIPFGIQHLKLAILSLTPIGQTVVAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ0</accession>
    <name>B1KQJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324575.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1945"/>
    <dbReference type="EnsemblBacteria" id="ACA86229">
        <property type="protein sequence ID" value="ACA86229"/>
        <property type="gene ID" value="Swoo_1945"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1945"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1271419_0_0_6"/>
    <dbReference type="OMA" id="AIGINWT"/>
    <dbReference type="OrthoDB" id="1292619at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="25561" checksum="202C67C3FA55DA40" modified="2008-04-29" version="1">MTLTIPLIDIPFELRHTCWFCAEPCNDSFQYHANSHTPHPSLAVPACKECLKLAEKHKLTSIWECQIAVKDELMRIYAKHLAIGINWTEQELIDSEFSCKVFEGFKKSGWMMYLIARDRVNAHSWSISIDGVPLDIEERETSFDFDGVKYSSLSKAIKHYSETLGLDKHFLQAIVSQVGRNRFAYAVRLCRINIASNKRTKQEVLKDLALEQGEELSDSTWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM4</accession>
    <name>B1KQM4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 11 12">Uridine kinase</fullName>
            <ecNumber evidence="7 11 12">2.7.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytidine monophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Uridine monophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">udk</name>
        <name evidence="14" type="ordered locus">Swoo_1979</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + cytidine = ADP + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11 12">
            <text>ATP + uridine = ADP + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5 11 12">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11 12">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 11 12">Belongs to the uridine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="7 11 12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324609.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1979"/>
    <dbReference type="EnsemblBacteria" id="ACA86263">
        <property type="protein sequence ID" value="ACA86263"/>
        <property type="gene ID" value="Swoo_1979"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1979"/>
    <dbReference type="eggNOG" id="COG0572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021278_1_2_6"/>
    <dbReference type="OMA" id="TTLKPMH"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00551">
        <property type="entry name" value="Uridine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026008">
        <property type="entry name" value="Uridine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="13">
        <location>
            <begin position="7"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="211" mass="23669" checksum="FDF1C28ADF270854" modified="2008-04-29" version="1">MNSQCVIIGIAGASASGKSLIAKTIFEELCRDLGTDQIGVIAEDAYYRDQGHLSMEQRVLTNYDHPKALDHELLCRHLQALKTGEAVEIPTYSYSDHTRMADTIKMTPKKVIILEGILLLTDPGLRGLMDASVFMDTPLDICFMRRLARDVAERGRTMESVMAQYTETVRPMFLQFIDPSKQYADIIVPRGGKNRIATDILKARIQHLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR44</accession>
    <name>B1KR44_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323209.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0565"/>
    <dbReference type="EnsemblBacteria" id="ACA84861">
        <property type="protein sequence ID" value="ACA84861"/>
        <property type="gene ID" value="Swoo_0565"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0565"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_3_6"/>
    <dbReference type="OMA" id="WHFHKEL"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="184"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="33656" checksum="C9CD0AC59A77B15C" modified="2008-04-29" version="1">MKPMCEKVIPSSNSSWRFVKYQLPNIDFNWHYHPEYEICLTLNSQGLRYIGDHIEEYSEPDLVFVGPHMPHTWHSSINEDESTQIVYVAQIPKLWLDGQVAEHPEMQGLEEMLERSSRGIFYSPESTEKALSLFQQMESADPFSRYILLMNLLNVMLKDAQSKLLSSRFFTYGDKTDSGIDKLDRVIEYIYGNFDRGLYADELAAIAHMSTNHFHRFFKKRTERTLTEFINQLRIGKACKLLINSNHPISVISDQCGFNNISNFNRQFLSIKGSTPSRFRKSLRLKHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR83</accession>
    <name>B1KR83_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RcpC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323248.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0604"/>
    <dbReference type="EnsemblBacteria" id="ACA84900">
        <property type="protein sequence ID" value="ACA84900"/>
        <property type="gene ID" value="Swoo_0604"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0604"/>
    <dbReference type="eggNOG" id="COG3745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088598_0_0_6"/>
    <dbReference type="OMA" id="HELHADS"/>
    <dbReference type="OrthoDB" id="1031576at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031571">
        <property type="entry name" value="RcpC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16976">
        <property type="entry name" value="RcpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RcpC" evidence="2">
        <location>
            <begin position="118"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="30622" checksum="0473343E7B6CECD1" modified="2008-04-29" version="1" precursor="true">MLNSKLIFIIAFIAVLTGLYGVADKLLSTSESVTQPVSDDGIAKTFTLWQTKSSLNKGEHLSLADLKRVQLGRDESLALGVNADVELNLDPQSLLNSSVEAGQYLFPEQLSHPGESGYLNLITREGMTLYPLTVATRNMIQDYILPGDEIDIMTVSSPQHNLANDMSRLDDFIGLRASMLMKRVRVISVADSDTDSQSQSSKISPSMKSSDKSQTRIVIEVDPEDLPRLTLAQRTMHIEVFHSQSYRAKPEADVSDVINNYTGVVELRGASENSVGGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRB4</accession>
    <name>B1KRB4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Large ribosomal RNA subunit accumulation protein YceD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA accumulation protein YceD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2037</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in synthesis, processing and/or stability of 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DUF177 domain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324667.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2037"/>
    <dbReference type="EnsemblBacteria" id="ACA86321">
        <property type="protein sequence ID" value="ACA86321"/>
        <property type="gene ID" value="Swoo_2037"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2037"/>
    <dbReference type="eggNOG" id="COG1399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094127_2_1_6"/>
    <dbReference type="OMA" id="TLLCQRC"/>
    <dbReference type="OrthoDB" id="1665714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039255">
        <property type="entry name" value="YceD_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38099">
        <property type="entry name" value="PTHR38099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19099" checksum="B14F2B1BADC809E4" modified="2008-04-29" version="1">MQTVKIPVSIDPIRAAASQLSYEGSIPGKQLKRLNELSAGDCSDVAVSFECGVDIQGIVYLKGKAVTELTLNCQRCMTLYTTKVTVDFNFTPCGNEAEIDELPDAYDPIECNEIGEVRLHQLIEDELIIAMPLIPMHADESCGKGDKDIVVGEIEPSQEERPNPFAVLEKLKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRC2</accession>
    <name>B1KRC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324675.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2045"/>
    <dbReference type="EnsemblBacteria" id="ACA86329">
        <property type="protein sequence ID" value="ACA86329"/>
        <property type="gene ID" value="Swoo_2045"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2045"/>
    <dbReference type="eggNOG" id="ENOG5032JXA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2025146_0_0_6"/>
    <dbReference type="OMA" id="CLAVINW"/>
    <dbReference type="OrthoDB" id="1895832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="122" mass="13044" checksum="31AB261E1D292ABD" modified="2008-04-29" version="1">MLNLIVVPLMPLVGALTANLNELIRGESAKLHPNMSIGMKTFTLAAASFAVVWFALLITAIYTSSNNSTLAGIEVLILFLAGLGLTAVAKGSRFISDKAQLWIYRLALPFILLASTLVVHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRE2</accession>
    <name>B1KRE2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324694.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2065"/>
    <dbReference type="EnsemblBacteria" id="ACA86349">
        <property type="protein sequence ID" value="ACA86349"/>
        <property type="gene ID" value="Swoo_2065"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2065"/>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_330621_0_0_6"/>
    <dbReference type="OMA" id="AERVFTQ"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="486"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="612"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="872" mass="98908" checksum="E64C1DC51E920129" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF1</accession>
    <name>B1KRF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mammalian cell entry related domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2074</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324703.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2074"/>
    <dbReference type="EnsemblBacteria" id="ACA86358">
        <property type="protein sequence ID" value="ACA86358"/>
        <property type="gene ID" value="Swoo_2074"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2074"/>
    <dbReference type="eggNOG" id="COG1463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018765_3_1_6"/>
    <dbReference type="OMA" id="HHVEIKA"/>
    <dbReference type="OrthoDB" id="855063at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="3">
        <location>
            <begin position="43"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="3">
        <location>
            <begin position="289"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="550" mass="60655" checksum="B1D15801E8CA8724" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCW4</accession>
    <name>B1KCW4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Peptide deformylase</fullName>
            <shortName evidence="4">PDF</shortName>
            <ecNumber evidence="4">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 4">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">def</name>
        <name evidence="5" type="ordered locus">Swoo_0038</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322688.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0038"/>
    <dbReference type="EnsemblBacteria" id="ACA84339">
        <property type="protein sequence ID" value="ACA84339"/>
        <property type="gene ID" value="Swoo_0038"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0038"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_2_1_6"/>
    <dbReference type="OMA" id="VCIQHEI"/>
    <dbReference type="OrthoDB" id="1649129at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="19338" checksum="EEAD77B2C40E533A" modified="2008-04-29" version="1">MSLLKVLRFPDEKLRTIAKPVTEFNADLQTQIDNMFETMYEEKGIGLAATQVDYHHQLIVMDLQDEVERPKVFINLEIVASSGHFENEEGCLSVPGIFANVERAEHVTIKALDREGNEFTLEADGLFGICLQHELDHLKGKLFVDYLSPLKRQRIKQKLEKAARQEKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD62</accession>
    <name>B1KD62_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alkanal monooxygenase</fullName>
            <ecNumber evidence="7">1.14.14.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Bacterial luciferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3635</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Light-emitting reaction in luminous bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a long-chain fatty aldehyde + FMNH2 + O2 = a long-chain fatty acid + FMN + 2 H(+) + H2O + hnu</text>
            <dbReference type="Rhea" id="RHEA:17181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the bacterial luciferase oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.3" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326230.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3635"/>
    <dbReference type="EnsemblBacteria" id="ACA87897">
        <property type="protein sequence ID" value="ACA87897"/>
        <property type="gene ID" value="Swoo_3635"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3635"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_3_0_6"/>
    <dbReference type="OMA" id="LEHHFTE"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047646">
        <property type="term" value="F:alkanal monooxygenase (FMN-linked) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008218">
        <property type="term" value="P:bioluminescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01096">
        <property type="entry name" value="Alkanal_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033924">
        <property type="entry name" value="Alkanal_monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018235">
        <property type="entry name" value="Bacterial_luciferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002103">
        <property type="entry name" value="Luciferase_bac/NFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00089">
        <property type="entry name" value="LUCIFERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00494">
        <property type="entry name" value="BACTERIAL_LUCIFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="5 7" id="KW-0455">Luminescence</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0599">Photoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="356" mass="40449" checksum="AFE3039229796F15" modified="2008-04-29" version="1">MKFGNICFSYQPPGETHKQVMDRFVRLGVASEELGFDTYWTLEHHFTEFGLTGNLFVAAANLLGRTKTLNIGTMGVVLPTAHPTRQLEDLLLLDQLSKGRFNFGVVRGLYHKDFRVFGVNMEESRSITQNFHEMIMEGTQTGRIGSDSEHIEFPEVEVYPTAYSSEIATCMTAESASTTEWLAKKGLPMVLSWIIPTNEKKAQMELYNEIALEHGHDISKIDHCMTFICSVDHDKQKAREVCRAFLTNWYDSYVNATNIFNDSNQTRGYDYHKGQWRDFVLKGHTNTNRRVDYSHEINPVGTPEECIEIIQRDIDATGITNITCGFEANGSEDEIVASMERFMTLVAPFLKEPNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA5</accession>
    <name>B1KDA5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326273.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3678"/>
    <dbReference type="EnsemblBacteria" id="ACA87940">
        <property type="protein sequence ID" value="ACA87940"/>
        <property type="gene ID" value="Swoo_3678"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3678"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115862_2_0_6"/>
    <dbReference type="OMA" id="TWDFQAP"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="16426" checksum="B4FE5ECC834561F3" modified="2008-04-29" version="1">MSQTATRKFTLDESKEFANAVEQKIAEFNWQQWEVSERLPLGLKLESETGELLAGFSARTFGNWLQIDNLWVSESLRGQSIGAQLLTEAESIAIERGCIYAILDTLNFQARPFYEARGYTLQWTQEAYPKTGCKYFMVKHLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDE9</accession>
    <name>B1KDE9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323297.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0654"/>
    <dbReference type="EnsemblBacteria" id="ACA84950">
        <property type="protein sequence ID" value="ACA84950"/>
        <property type="gene ID" value="Swoo_0654"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0654"/>
    <dbReference type="eggNOG" id="COG1639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060731_0_0_6"/>
    <dbReference type="OMA" id="QITDPYP"/>
    <dbReference type="OrthoDB" id="552121at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="99"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="380" mass="43372" checksum="6575DB852CEB52EB" modified="2008-04-29" version="1">MAISVAGGVRPGKVIEIEHRLYQQLIVGKQKSSSMFDELDAELENDANKLAIEREAVLERLTKQIEAKDIFDRVSKQLIDTVSCAVDHRLASADSVIKSAGINESQLLMLELLQSNNLDINRLRPLIANESWLVRDLLNIVNSSSFRHRRPQGSDVKVTDIKLVLNFIGIENIKLLVPYFCLRNWLPSGHANLLWTTRKLWRYSMVSAIAAQALAKLHEKDGVFVYTCTLLSQLGPSVVLKNSALLFEETWGVWLREASNSRDKELYDAVLATEFPSQRVYELVIEHGDRLNWQLLEQLNFSDSAMGAVMAELDNNLSYKELSENASIVARANCYAKVVLLEEMRELSVQEKRIMFDYYELSEQEIIRLKAQNYRKLDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDI0</accession>
    <name>B1KDI0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Flavohemoprotein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nitric oxide dioxygenase</fullName>
            <shortName evidence="13">NO oxygenase</shortName>
            <shortName evidence="13">NOD</shortName>
            <ecNumber evidence="13">1.14.12.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">hmp</name>
        <name evidence="18" type="ordered locus">Swoo_0685</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 13">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="13">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323328.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0685"/>
    <dbReference type="EnsemblBacteria" id="ACA84981">
        <property type="protein sequence ID" value="ACA84981"/>
        <property type="gene ID" value="Swoo_0685"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0685"/>
    <dbReference type="eggNOG" id="COG1017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_12_0_6"/>
    <dbReference type="OMA" id="ADIHYEV"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051409">
        <property type="term" value="P:response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01252">
        <property type="entry name" value="Hmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023950">
        <property type="entry name" value="Hmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="PTHR43396:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0216">Detoxification</keyword>
    <keyword evidence="13" id="KW-0274">FAD</keyword>
    <keyword evidence="13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 13 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="9 13" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13 15" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 15" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="16">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="17">
        <location>
            <begin position="152"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Reductase" evidence="13">
        <location>
            <begin position="149"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="13">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="206"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="272"/>
            <end position="277"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="393"/>
            <end position="396"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Involved in heme-bound ligand stabilization and O-O bond activation" evidence="13">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Influences the redox potential of the prosthetic heme and FAD groups" evidence="13">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="site" description="Influences the redox potential of the prosthetic heme and FAD groups" evidence="13">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACA84981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="400" mass="44846" checksum="E64AAEFAF612E28B" modified="2008-04-29" version="1">MLSEKHISIVKSTIPLLESAGTAITEHFYQRMFSHNPELKDIFNMSHQKTGGQPAALFNAVAAYAKNIDNLGALSGAVERIAHKHTSFNIQPDHYPIVGHHLLETLRELAPDAFTPDVEEAWGAAYGLLAGIFIKREDELYQKSATQAGGWLGARQFRVTQKREESSLVTSFVFTPVDQQPVIGYEPGQYLGIKVAPTNHEFQEIRQYSLSDKPNASSYRISVKREAIGIPGVVSNHLHDHLNLDDIVDIYPPAGDFHYIEREAPVVLISAGVGVTPMQSMLEMLADKAFDKPVFYLHACESVEQHSFNQRVNLLSEKINLQHHTWYRDIGSLNKDQMSANVQQGFMNLALLKSQLPLTDGDFYLCGPVAFMQFAKQQLLELNVSEEHIHYEVFGPHAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDK1</accession>
    <name>B1KDK1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323349.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0707"/>
    <dbReference type="EnsemblBacteria" id="ACA85002">
        <property type="protein sequence ID" value="ACA85002"/>
        <property type="gene ID" value="Swoo_0707"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0707"/>
    <dbReference type="eggNOG" id="COG4938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032548_0_0_6"/>
    <dbReference type="OMA" id="QVIIETH"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014592">
        <property type="entry name" value="P-loop_UCP034888"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034888">
        <property type="entry name" value="P-loop_UCP034888"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="185"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="374" mass="41853" checksum="C543B414377365DB" modified="2008-04-29" version="1">MLKKLSISNFKSIDKEKLKIAPLTILTGINSTGKSTVIQAILLLLRFAIPVNRVTLNKVVSAYVSPRDTRNRYTNQSDINIELELNSEVFDSLLLQTIKSEDDQVLFRGGIKPTEKYIGSGEFNPAEPPLTYVYEPEEGASNCSELFYLNATRLGPQSTSEVGDFKVGLLGELIFSTYDQIKNQALPEKLVKFSESSTIGYQVSQWLSKITDSKLELRTEKINSEQIKVSFNSDGLEELSPQNLGAGISYLAKVVILCFMAKKGDLVIIENPEIHLHPKSQAQLGVFFSFIASSGIQLIIETHCEHLIQKIRGEVRNEAIECEDVVIHYKSATLKPFDTLFLDANGHYCDQEENRISFPKGFFDTSVDTLLSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM0</accession>
    <name>B1KDM0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carboxyl-terminal protease</fullName>
            <ecNumber evidence="6">3.4.21.102</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324762.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2133"/>
    <dbReference type="MEROPS" id="S41.001"/>
    <dbReference type="EnsemblBacteria" id="ACA86417">
        <property type="protein sequence ID" value="ACA86417"/>
        <property type="gene ID" value="Swoo_2133"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2133"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016199_1_0_6"/>
    <dbReference type="OMA" id="HHYSKPP"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020992">
        <property type="entry name" value="Tail_Prtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040573">
        <property type="entry name" value="TSP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11818">
        <property type="entry name" value="DUF3340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17804">
        <property type="entry name" value="TSP_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="238"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="638"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="649"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="690" mass="77770" checksum="28E24555BB296E57" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDT9</accession>
    <name>B1KDT9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324830.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2204"/>
    <dbReference type="EnsemblBacteria" id="ACA86486">
        <property type="protein sequence ID" value="ACA86486"/>
        <property type="gene ID" value="Swoo_2204"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2204"/>
    <dbReference type="eggNOG" id="ENOG50337FW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091012_0_0_6"/>
    <dbReference type="OMA" id="MVMEDGQ"/>
    <dbReference type="OrthoDB" id="1624315at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="267" mass="29695" checksum="ACCCDD8685C6F1E8" modified="2008-04-29" version="1" precursor="true">MKVLKLVTFSLSIVFASVILAGVYRFNLTDDDIYIEMSDGTVLPYDEAVILEKKTKNEEKSAALREGIFTADTQESSLVMRKLFSLQTTTPFNIMLPDSNSLVALTHFLGGDEHESQDNSELAAGSYQHGEVRGSVLLDYYKITPLNFPEGSSTTSSMHSDNDKALFTFVAPFAVTTQGSGVFWYLGLFNIDYQTNRLSHIDSEFVGDRVEIKHIEPSEPFDSPYSITVTYNERGPLQAMSDKPSMRQMVELRVSKGEIINLSAISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE33</accession>
    <name>B1KE33_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Putrescine aminopropyltransferase</fullName>
            <shortName evidence="4">PAPT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Spermidine synthase</fullName>
            <shortName evidence="4">SPDS</shortName>
            <shortName evidence="4">SPDSY</shortName>
            <ecNumber evidence="4">2.5.1.16</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">speE</name>
        <name evidence="7" type="ordered locus">Swoo_0724</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + S-methyl-5'-thioadenosine + spermidine</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323366.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0724"/>
    <dbReference type="EnsemblBacteria" id="ACA85019">
        <property type="protein sequence ID" value="ACA85019"/>
        <property type="gene ID" value="Swoo_0724"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0724"/>
    <dbReference type="eggNOG" id="COG4262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034289_1_0_6"/>
    <dbReference type="OMA" id="SFGEWGY"/>
    <dbReference type="OrthoDB" id="1613081at2"/>
    <dbReference type="UniPathway" id="UPA00248">
        <property type="reaction ID" value="UER00314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4 5" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="1 4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="6">
        <location>
            <begin position="259"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-methyl-5'-thioadenosine binding" evidence="4">
        <location>
            <begin position="405"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 5">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="576" mass="63555" checksum="D43F65A3AD28731E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE89</accession>
    <name>B1KE89_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323422.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0780"/>
    <dbReference type="EnsemblBacteria" id="ACA85075">
        <property type="protein sequence ID" value="ACA85075"/>
        <property type="gene ID" value="Swoo_0780"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0780"/>
    <dbReference type="eggNOG" id="ENOG50343ZZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152622_0_0_6"/>
    <dbReference type="OMA" id="RATDKRC"/>
    <dbReference type="OrthoDB" id="1742091at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021378">
        <property type="entry name" value="DUF3010"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11215">
        <property type="entry name" value="DUF3010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="14853" checksum="FA0ED0FBECD605CC" modified="2008-04-29" version="1">MLIAGMFLKANEVRIVTLAGSRVSHQLVAPKVNKFTLVKNPSQSEVAQFGEAIVAYCDDHKVELIVLNRRATSGQGAGGAGTFLMEGVILALARINVELVHPATVRATDKRNAEFKDLKPKTVDLGKAYDLAFEFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE94</accession>
    <name>B1KE94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323427.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0785"/>
    <dbReference type="EnsemblBacteria" id="ACA85080">
        <property type="protein sequence ID" value="ACA85080"/>
        <property type="gene ID" value="Swoo_0785"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0785"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_522627_0_0_6"/>
    <dbReference type="OMA" id="IMGFAHY"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="251"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="485" mass="54784" checksum="55A9063F8693FDDF" modified="2008-04-29" version="1">MNFSFKDVVNVFGICLLLSILQLSRFLVIDNTTKMSLNPQQMQQDLDTLVAEVSQHSTFSALDPLLLQSIENRVDSLRYLYSLGIDSSRFHAEIAKLLAQLNDPGIKLSSSTYSTGQLPFSLKPMGQLWLALDDSETPLDLEHPFISHIDGVALTYWLKTARKFISSSQQEDLALTLTWLSRLDLLRAEMGLPLGDTVSLTVTNDEESKKELTLTVHSQTKPPYKELVIESQDKDTNPIKITDLDKLSTNRKLFSQLETAFENPLTVVDLRQAKGYSDKLLSLLTNEFSPSLPESANPVFTLARYRRASNFKSDYLRADYLHPFNELNFFEQVQLSEIKVKLETQDSDNFSQLYARKSRPQAREAQRSNRLALIIGPQCRQECEWIAYLTKAWPRVTLIGEKTSGDLGKHYRFTLPNSKLNIALTSSLHYNLQGALISGVGTEPDITFTDSEPLHWQSLVTQLNNQASPENTQQTPKSFVTAISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF5</accession>
    <name>B1KEF5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Coenzyme PQQ synthesis protein B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Pyrroloquinoline quinone biosynthesis protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pqqB</name>
        <name evidence="9" type="ordered locus">Swoo_2252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the transport of PQQ or its precursor to the periplasm.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PqqB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324876.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2252"/>
    <dbReference type="EnsemblBacteria" id="ACA86533">
        <property type="protein sequence ID" value="ACA86533"/>
        <property type="gene ID" value="Swoo_2252"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2252"/>
    <dbReference type="eggNOG" id="COG1235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061120_0_0_6"/>
    <dbReference type="OMA" id="FYIPGCA"/>
    <dbReference type="OrthoDB" id="1712770at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16274">
        <property type="entry name" value="PQQB-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00653">
        <property type="entry name" value="PQQ_syn_PqqB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011842">
        <property type="entry name" value="PQQ_synth_PqqB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02108">
        <property type="entry name" value="PQQ_syn_pqqB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Lactamase_B" evidence="8">
        <location>
            <begin position="50"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="33245" checksum="FE3690FCFBC03913" modified="2008-04-29" version="1">MQILILGSAAGGGFPQWNCHCDNCEGVRSGRIKAQARTQSSIAVSPDGENWVLINASPDIRQQINQSPQLWPDEGQRGTKIRAAVLSDSQIDHTTGLLTLREGLPLPVYCTDVVHEDLSGAYPLFNLLSHWHGGLTHRAIGTDPQTPFTVEQVSGLVFYPVPLESNAPPYSPYRDDIVPGNNIGLKILDSNTGKYLFYAPGIVKSNSLVEAMLADAECALIDGTLWLDDEMIAKGFSNKLGSDMGHMPVNGEFGTVALLKKFDIKHKILIHINNTNPILNEESAEHSYVINNGVEIATDGMEIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF6</accession>
    <name>B1KEF6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FMN-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2253"/>
    <dbReference type="EnsemblBacteria" id="ACA86534">
        <property type="protein sequence ID" value="ACA86534"/>
        <property type="gene ID" value="Swoo_2253"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2253"/>
    <dbReference type="eggNOG" id="COG0348">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3901">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013077_0_0_6"/>
    <dbReference type="OMA" id="SHHEPVF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011399">
        <property type="entry name" value="NosR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036354">
        <property type="entry name" value="NosR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="537"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="574"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="2">
        <location>
            <begin position="67"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="703" mass="79884" checksum="B21035A470FFBADB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI9</accession>
    <name>B1KEI9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324910.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2286"/>
    <dbReference type="ESTHER" id="shepa-a8h6h3">
        <property type="family name" value="PhoPQ_related"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86567">
        <property type="protein sequence ID" value="ACA86567"/>
        <property type="gene ID" value="Swoo_2286"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2286"/>
    <dbReference type="eggNOG" id="COG4287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_610697_0_0_6"/>
    <dbReference type="OMA" id="AGVMATC"/>
    <dbReference type="OrthoDB" id="505680at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009199">
        <property type="entry name" value="PhoPQ-act_pathogen-rel_PqaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31497">
        <property type="entry name" value="PTHR31497"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10142">
        <property type="entry name" value="PhoPQ_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="494" mass="55159" checksum="6AAD8DEBA5412582" modified="2008-04-29" version="1" precursor="true">MKKALLSIVVFLICVTLTLFLSRGAIKDYLSYRFIGPASYFDLDEIKDQSTLDVEIKQDKIVDSQSRPGEKVRVIKLSFTSQKWHGSTWRHPATIYVPANYQGEGNVGIIATNRAFKGQHETESTAGGHQNQLVESNVVPEHLRHLFDRQKIPGTELNTEAEYAEVTAIDLHTPIMIFPNPATLIFDKDESNLMGYGLQMAIDTFDLSWIGYAPIATSYLKAITLLESIEGIAAKKAVIMGCSKRGFASSIALGAGDDRLAGVMATCYYGGNVLYDIMRKFESFGTDVGGPAVERDGPAFQPADKLLAKMNGPAGNLATMAFDPYLWKKKINTPYFVALGTNDEFFGLGAPNGMMSELKGDKAFLYVDNLRHSWVSKKHLHSWRTWLAHVFYDRKLPTVEVESQVEGAKVNVIADVASSNTLKHVRLYYSVNRSLDWREAKWEFKAMKMVNGKFQSQLEKIDGKNLAYYVEVEDFHDKGGIGYLSSLVEINRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEJ1</accession>
    <name>B1KEJ1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cardiolipin synthase A</fullName>
            <shortName evidence="12">CL synthase</shortName>
            <ecNumber evidence="12">2.7.8.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">clsA</name>
        <name evidence="14" type="ordered locus">Swoo_2290</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol</text>
            <dbReference type="Rhea" id="RHEA:31451"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324911.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2290"/>
    <dbReference type="EnsemblBacteria" id="ACA86569">
        <property type="protein sequence ID" value="ACA86569"/>
        <property type="gene ID" value="Swoo_2290"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2290"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038053_1_0_6"/>
    <dbReference type="OMA" id="TRFILDW"/>
    <dbReference type="OrthoDB" id="1881748at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008808">
        <property type="term" value="F:cardiolipin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00190">
        <property type="entry name" value="Cardiolipin_synth_ClsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022924">
        <property type="entry name" value="Cardiolipin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030840">
        <property type="entry name" value="CL_synthase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04265">
        <property type="entry name" value="bac_cardiolipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="485" mass="55596" checksum="125D4D9AB783B18F" modified="2008-04-29" version="1">MEDFYQILTLVGLFAYWLIAAGVVIRVIIKRRSIGVSLAWMMVIYFVPFFGVLGYLLIGEQNWGKARENRAKLMYAPYRKWFADLYQFRQYRPKELTEYGHSISSLCEQRLGIPSLGNNQLELQSSPQQILHSLIADIEGAQSSINLEFYIWHPGGLADKVAQALIDAAKRGVEIKLLLDAAGSRQFFKSHWPKQFKQSGIEVTEALVVSPLRMFFRRLDLRMHRKIVIIDNQIGYTGSMNLVDPAFFKQNAHVGQWVDVMVRITGSNVPVLNTINSWDWEVETNHRQLPEAPECIKLNADHPIDMLQVIPSGPGMPSEIIHQVLLLSIYQAKSKIVITTPYFVPSENLMFALTSAAQRGVIVELIIPERNDSTMVKWASRSFFGELLSAGVKIYRFKGGLLHTKSVVIDQNHCLIGTVNLDMRSLWLNNEVTLAVDDLAFTQKLSQLQQSYIDDSTQLEHERWRKRPVYKRIIEQFFYMFSPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEK2</accession>
    <name>B1KEK2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2301"/>
    <dbReference type="EnsemblBacteria" id="ACA86580">
        <property type="protein sequence ID" value="ACA86580"/>
        <property type="gene ID" value="Swoo_2301"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2301"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082632_6_0_6"/>
    <dbReference type="OMA" id="EAKNIKM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="125" mass="13996" checksum="8E255B514B3D590B" modified="2008-04-29" version="1">MNFSNFKKAPIVSLQGQPVLLFTQQHTSLLMALEQKKVKLFSECRNGYCGACKTKIISGGVTYHTEPLVHLEKDECLPCCCTPNSDLDLELPTQGVTLTPKREENAKLIPQEQIKETQTVCTDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEL2</accession>
    <name>B1KEL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protease-associated PA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3768</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326359.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3768"/>
    <dbReference type="EnsemblBacteria" id="ACA88027">
        <property type="protein sequence ID" value="ACA88027"/>
        <property type="gene ID" value="Swoo_3768"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3768"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003205_0_0_6"/>
    <dbReference type="OMA" id="AAYTHDR"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04852">
        <property type="entry name" value="Peptidases_S8_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020008">
        <property type="entry name" value="GlyGly_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034197">
        <property type="entry name" value="Peptidases_S8_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PTHR10795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03501">
        <property type="entry name" value="GlyGly_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767290" evidence="6">
        <location>
            <begin position="21"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="209"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="467"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="PPC" evidence="9">
        <location>
            <begin position="901"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1265" mass="132305" checksum="EDE7737C00AC2006" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU4</accession>
    <name>B1KEU4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323442.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0800"/>
    <dbReference type="EnsemblBacteria" id="ACA85095">
        <property type="protein sequence ID" value="ACA85095"/>
        <property type="gene ID" value="Swoo_0800"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0800"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_619418_0_0_6"/>
    <dbReference type="OMA" id="MGFKVYF"/>
    <dbReference type="OrthoDB" id="556236at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="423" mass="48457" checksum="0E051D162987DEEE" modified="2008-04-29" version="1">MQVTSIERVKQAFIAGIWATLVSITLGFGFKVWLAQWMAKEDLALYHTVVDIISLSLILMTGFRSSMVVSYSQTQNDKDITNLFRYSLIAVVLLTWGIVLPYIKHQLHIDVEYFHLVGIILGMGFKVYFTNQIAMYRLYEISNRVTWLEPLGQILTFLTCFYLLEQTPISSLFFSLMLSSTTVAVYMFFNRRKQIATTPIGPVNMDTNLRNFMKKSFTASLEAGASILMIYITVLLTIGHFSIDELGDFQVVVRPIIAYLTLLFVFPIYRFVFPELAVCVRNQDWQQIKQIKHWVYKMSLIISSLFFISMLLFSHEIVALVFPEQYAKSAPVLMHFSMFFLFMMLNAYQLAFIKAHGLFTQSLLIRGSGIVALIASYYIYSQITDNVVAVILALGTGYLLMFLISGQVEKRILKQDKLIPSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW3</accession>
    <name>B1KEW3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0819</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323461.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0819"/>
    <dbReference type="EnsemblBacteria" id="ACA85114">
        <property type="protein sequence ID" value="ACA85114"/>
        <property type="gene ID" value="Swoo_0819"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0819"/>
    <dbReference type="eggNOG" id="COG2807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038046_1_0_6"/>
    <dbReference type="OMA" id="RDPLAWQ"/>
    <dbReference type="OrthoDB" id="806182at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="11"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="411" mass="44273" checksum="A99D46D5DD5DF4A7" modified="2008-04-29" version="1">MTQVQTSRLTSTAYLLLGVLLIAISLRSPITGVGPLLDLIREQLHLSATQAGMLTTLPLLAFAFFSPLASKLAQKKGLEHALMISLFLLLTGITIRSQGSSISLFTGTLIIGAGIAIANVLLPSLMKRDFPNRVTTITSIYVLMMGVGSALSASLAIPLTHVAESLSIKLIPTWAFSLGSIILFPIIAILIWLPQMRNHTPAAENTSKLDSHSYLWRSPSAWHITLFLALNSFLMYIFISWFPTILVDTGYSHEQAGVIHGLLQLFTAVPAIVLIPIISRIQDKRLLSLGLTLLGMIAVIGLILAPSLAILWAMLFGFGAGGGFILALAFISLRTTDIHQAATLSGMAQCLGYLLAATGPIIMGAIHEYSGSWTPPLILCAVANLLWSIFSLLASRSEKIHKQPKQSFQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF73</accession>
    <name>B1KF73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324956.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2335"/>
    <dbReference type="EnsemblBacteria" id="ACA86614">
        <property type="protein sequence ID" value="ACA86614"/>
        <property type="gene ID" value="Swoo_2335"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2335"/>
    <dbReference type="eggNOG" id="COG3182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066006_0_0_6"/>
    <dbReference type="OMA" id="SWTDIDE"/>
    <dbReference type="OrthoDB" id="1111172at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="28126" checksum="5AEEBF1AB7C32C7E" modified="2008-04-29" version="1">MNLLKISRKYHRYLMLFLGVQFVIWTVSGAYMVIIDIDYIHGDTLVHNHQTKIAPDDVHYSLAQLTQAYPKAEQLELGMLIDKPVYRFKQGDQLHMLNASTGAMLSPLPKESALAIAQHEYTGMGNIALIELITENPPFELSGRHLPAWRVNYDDFGSPSLYISALSGKVVTKRHEFWRTFDLMFSLHVMDYEEEDPSNWLLFWFVCFALLASLFGLILTYYQVFKNDTVKPTAQVSSSHNEGVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFB9</accession>
    <name>B1KFB9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_2381</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325002.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2381"/>
    <dbReference type="EnsemblBacteria" id="ACA86660">
        <property type="protein sequence ID" value="ACA86660"/>
        <property type="gene ID" value="Swoo_2381"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2381"/>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003705_0_1_6"/>
    <dbReference type="OMA" id="HDMAGFY"/>
    <dbReference type="OrthoDB" id="771837at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764376" description="Aminopeptidase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1_N" evidence="12">
        <location>
            <begin position="33"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="10">
        <location>
            <begin position="240"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1_C" evidence="11">
        <location>
            <begin position="526"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="859" mass="96395" checksum="53B6E30AEFAFD13C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC6</accession>
    <name>B1KFC6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325009.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2388"/>
    <dbReference type="EnsemblBacteria" id="ACA86667">
        <property type="protein sequence ID" value="ACA86667"/>
        <property type="gene ID" value="Swoo_2388"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2388"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1432782_0_0_6"/>
    <dbReference type="OMA" id="VCYFKCN"/>
    <dbReference type="OrthoDB" id="1622025at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="184" mass="20494" checksum="82888C0922B602F2" modified="2008-04-29" version="1">MIEALAPEHFEDVIALGNKVHGDGYLDLQLMQSLYKKGIKNEINANFVALLNNELVGFRLTYAPGNWQPDNWCLPDAWGVEPDKVCYFKCNTVAKEHRGVGIGGKLLQASIAATKYQGAKAGISHLWKDSPNNSAVNYFTKAGGVLIKEYPNRWNDTKEHPDYICILCGSECHCTACEMILIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK8</accession>
    <name>B1KFK8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Respiratory-chain NADH dehydrogenase domain 51 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_3925</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326513.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3925"/>
    <dbReference type="EnsemblBacteria" id="ACA88183">
        <property type="protein sequence ID" value="ACA88183"/>
        <property type="gene ID" value="Swoo_3925"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3925"/>
    <dbReference type="eggNOG" id="COG1894">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014881_3_1_6"/>
    <dbReference type="OMA" id="VATFYHH"/>
    <dbReference type="OrthoDB" id="688908at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="NADH_4Fe-4S" evidence="12">
        <location>
            <begin position="486"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA88183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="562" mass="61369" checksum="028262348F39C70B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN7</accession>
    <name>B1KFN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323550.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0909"/>
    <dbReference type="EnsemblBacteria" id="ACA85203">
        <property type="protein sequence ID" value="ACA85203"/>
        <property type="gene ID" value="Swoo_0909"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0909"/>
    <dbReference type="eggNOG" id="ENOG503190S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152555_0_0_6"/>
    <dbReference type="OMA" id="DYYCVEE"/>
    <dbReference type="OrthoDB" id="1697825at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="15443" checksum="8B2CF251CA5CCD57" modified="2008-04-29" version="1">MHDIIEQLQEMSETVPIPLELPTFDQLVMAEEEILMPLPGELKQYLLYASDVIYGSLEPVTVSDPNSHTFLPEVTAYAWSIGMPREYVAVCQQGNSFYCIDQEGQMLLWNEDGSESEYWESLWEWVEQVWMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFU7</accession>
    <name>B1KFU7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323610.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0970"/>
    <dbReference type="EnsemblBacteria" id="ACA85263">
        <property type="protein sequence ID" value="ACA85263"/>
        <property type="gene ID" value="Swoo_0970"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0970"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_6"/>
    <dbReference type="OMA" id="LDRFAPM"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="23298" checksum="CEB034D1D9694ED1" modified="2008-04-29" version="1">MGKPYSVLVVDDHPLLRRGICQLITSDSDFTLFGEAGSGLDALSAIEDNEPDIILLDLNMKGMTGLDTLNALRQEGVTSRIVILTVSDAKQDVIRIIRAGADGYLLKDTEPDLLLEKLKNAMQGHRVISESVEEYLYELKDAADEDDWLSNLTPRELQILEQVAEGKSNRMISELLHISEGTVKVHVKNLLRKGHAKSRTEMAVRYLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB0</accession>
    <name>B1KGB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326576.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3990"/>
    <dbReference type="EnsemblBacteria" id="ACA88247">
        <property type="protein sequence ID" value="ACA88247"/>
        <property type="gene ID" value="Swoo_3990"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3990"/>
    <dbReference type="eggNOG" id="ENOG503305B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147336_1_0_6"/>
    <dbReference type="OMA" id="FAASRFN"/>
    <dbReference type="OrthoDB" id="1971438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021490">
        <property type="entry name" value="DUF3144"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11342">
        <property type="entry name" value="DUF3144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="12010" checksum="AED0452BA75F9C1D" modified="2008-04-29" version="1">MSEAGKETTIFQLADQFIALANELSAKEQDVSKVGTALRFAASRFNAFEAALKSADLAAEKENALEWFVNEYKAMLNDNLDDHIKHPPVSHSEPAEEPAQDDAVQVFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGR1</accession>
    <name>B1KGR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325121.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2503"/>
    <dbReference type="EnsemblBacteria" id="ACA86780">
        <property type="protein sequence ID" value="ACA86780"/>
        <property type="gene ID" value="Swoo_2503"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2503"/>
    <dbReference type="eggNOG" id="ENOG5033ENS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1146121_0_0_6"/>
    <dbReference type="OMA" id="WAFIARA"/>
    <dbReference type="OrthoDB" id="1300443at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009677">
        <property type="entry name" value="DUF1266"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06889">
        <property type="entry name" value="DUF1266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="233" mass="27086" checksum="67BCEF174135E207" modified="2008-04-29" version="1">MNSSEQSGYNPDNLSSVKLWGLAVSALLTEMNELRHDVLHHHGTSDEDIKDLKHMMMRDWGIETREEYLNMLKWLREEGHNRSYMQMQDHLNTLSESAIDAYIDAHSHNVDRQSCLQLVRNYRHTLNIGGIGAWDDGRYVSICRWGASLGLFSEDECWEKIKQISLRVQQSYDSWHSFALSYIAGRQFWRNDATESFAKDEMDVVRRLTGDPKSPWNTLEWNLDLTENCNGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV3</accession>
    <name>B1KGV3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325163.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2545"/>
    <dbReference type="EnsemblBacteria" id="ACA86822">
        <property type="protein sequence ID" value="ACA86822"/>
        <property type="gene ID" value="Swoo_2545"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2545"/>
    <dbReference type="eggNOG" id="COG4319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1433582_0_0_6"/>
    <dbReference type="OMA" id="IYSEDAC"/>
    <dbReference type="OrthoDB" id="1468503at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767047" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="32"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="21721" checksum="3E7C952D955E2C71" modified="2008-04-29" version="1" precursor="true">MTFIKYTATCTIFLLLQLSSASANSDDNAALNQFYTQFTQAFETLDAQKVKNIYAEDACYIPENQSKAITMGRDNIIELYNKFFGKIKHKEARIEVDFRVLDRQVEANNATDIGYYLIRFHPPLDAEEPVSEFAGKFVTVSKKKKDGKWYLTVDTNNRSEPSFYYDAKPTPNLYYGHQFTPLTTAKNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX0</accession>
    <name>B1KGX0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endonuclease III</fullName>
            <ecNumber evidence="10">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nth</name>
        <name evidence="12" type="ordered locus">Swoo_2562</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325180.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2562"/>
    <dbReference type="EnsemblBacteria" id="ACA86839">
        <property type="protein sequence ID" value="ACA86839"/>
        <property type="gene ID" value="Swoo_2562"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2562"/>
    <dbReference type="eggNOG" id="COG0177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_3_0_6"/>
    <dbReference type="OMA" id="QIIWYGR"/>
    <dbReference type="OrthoDB" id="1381897at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01083">
        <property type="entry name" value="nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="11">
        <location>
            <begin position="38"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="212" mass="23849" checksum="2355E7098B3D1AFB" modified="2008-04-29" version="1">MNKEKRQAILSILRENNPHPETELNFSSPFELLVAVTLSAQATDVSVNKATDKLFPIANTAQSIYALGVDGLKEYIKTIGLYNNKAINVIKACEILIEKYNGEVPEDREALESLPGVGRKTANVVLNTAFGWPTIAIDTHIFRVANRTKFAMGKNVDQVEEKMLKVVPAEFKVDVHHWFILHGRYTCVARKPRCGSCLIEELCEFKEKVYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGY8</accession>
    <name>B1KGY8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4044</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326629.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4044"/>
    <dbReference type="EnsemblBacteria" id="ACA88300">
        <property type="protein sequence ID" value="ACA88300"/>
        <property type="gene ID" value="Swoo_4044"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4044"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064081_1_0_6"/>
    <dbReference type="OMA" id="IDWFLPH"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="3">
        <location>
            <begin position="123"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="2">
        <location>
            <begin position="276"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="368" mass="40898" checksum="CD010C94E224C4CB" modified="2008-04-29" version="1">MNVYINSTGHYLPGPPIDNDEIEDILGLVNGKKSRLKHKILQSNGIKTRHYAINQQQETQISNSEMAAHAGIKCLDASYISPHQIEMLSVATSQGDLVLPGFGSMVQAELDIPSVELQTSHGICSSSMMALKSAYTNIKAQESANALVIASELASRLFKHTRYEQVEGNEIDFNAEFLRWMLSDGAGALLLENQPRKTGKSLRIDWIKSFSHADVYPVCMSVGMPKNATKSWQDFPTYSEAEQAGALLLRQDVRLLDNIVSVGVNGFLKLLQDGMFKVPEIDHVLCHFSSAYFKSKIVEMLEVAGVQIPEKKWYTNLYERGNTGCASIFIMLDEFLATQDLSVGETLFCMVPESGRFNCAYMHLTVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH21</accession>
    <name>B1KH21_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326662.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4077"/>
    <dbReference type="EnsemblBacteria" id="ACA88333">
        <property type="protein sequence ID" value="ACA88333"/>
        <property type="gene ID" value="Swoo_4077"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4077"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_1_2_6"/>
    <dbReference type="OMA" id="ACGIPYW"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="464"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="548" mass="58922" checksum="85D494BC582AA430" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHM3</accession>
    <name>B1KHM3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Respiratory nitrate reductase, gamma subunit</fullName>
            <ecNumber evidence="15">1.7.99.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_2631</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.7.99.4" evidence="15"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325248.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2631"/>
    <dbReference type="EnsemblBacteria" id="ACA86908">
        <property type="protein sequence ID" value="ACA86908"/>
        <property type="gene ID" value="Swoo_2631"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2631"/>
    <dbReference type="eggNOG" id="COG2181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092378_1_0_6"/>
    <dbReference type="OMA" id="MVSGGFF"/>
    <dbReference type="OrthoDB" id="1873056at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023234">
        <property type="entry name" value="NarG-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036197">
        <property type="entry name" value="NarG-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003816">
        <property type="entry name" value="Nitrate_red_gam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02665">
        <property type="entry name" value="Nitrate_red_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103501">
        <property type="entry name" value="SSF103501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00351">
        <property type="entry name" value="narI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Nitrate_red_gam" evidence="14">
        <location>
            <begin position="6"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA86908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="25472" checksum="332C7BBE1580B027" modified="2008-04-29" version="1">MSNFNFFLFGIYPFIALSVFFIGCWIRYDREPYSWKADSSQLLDQKGFRLASNLFHIGIIFILGGHFVGLLTPESIYHHFISSPDKQLLAMVSGGFFGIVCLVGLVMLIKRRLNNPRVRATSRRSDIVVLFMLLIQLVLGLLTVVVSMGHLDGSVMILLATWTQSIATLQGVQAAEAIESVNFIYKLHILVGLTLIMIFPFTRLVHVISVPVKYFARSYQVVRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP5</accession>
    <name>B1KHP5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325270.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86930">
        <property type="protein sequence ID" value="ACA86930"/>
        <property type="gene ID" value="Swoo_2654"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2654"/>
    <dbReference type="HOGENOM" id="CLU_2048157_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="13607" checksum="39F00DEE2297DCAE" modified="2008-04-29" version="1">MDSFKFSPKSKKVLMLLVILALTPFAPELLLFMDVAGVEVAFTCLLIMIKPMKLWIECQIVKIKEFSRMMILAVKQHPVSDARVFAGHYFAFSLTFVITSSLFVSSSIWLPILVMGRYIA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV8</accession>
    <name>PSD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylserine decarboxylase proenzyme</fullName>
            <ecNumber evidence="1">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="1">Phosphatidylserine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="1">Phosphatidylserine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="1" type="primary">psd</name>
        <name type="ordered locus">Swoo_4180</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="1">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326765.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHV8"/>
    <dbReference type="SMR" id="B1KHV8"/>
    <dbReference type="STRING" id="392500.Swoo_4180"/>
    <dbReference type="EnsemblBacteria" id="ACA88436">
        <property type="protein sequence ID" value="ACA88436"/>
        <property type="gene ID" value="Swoo_4180"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4180"/>
    <dbReference type="eggNOG" id="COG0688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029061_4_1_6"/>
    <dbReference type="OMA" id="AIEWQLH"/>
    <dbReference type="OrthoDB" id="891720at2"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00662">
        <property type="entry name" value="PS_decarb_PSD_B_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033178">
        <property type="entry name" value="PSD_type1_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PTHR10067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0210">Decarboxylase</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-0670">Pyruvate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_1000131406" description="Phosphatidylserine decarboxylase beta chain" evidence="1">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_1000131407" description="Phosphatidylserine decarboxylase alpha chain" evidence="1">
        <location>
            <begin position="252"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="1">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="1">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="1">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="1">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00662"/>
        </source>
    </evidence>
    <sequence length="287" mass="31484" checksum="A3CA364AAE668BD1" modified="2008-04-29" version="1">MDKIKIALQYMMPKHLISRLVGKLAAAEMGSVTTAAIKWFIKQYKIDMSEAAQSSPEAYSTFNDFFTRALKPGIRPISDKKDYIVHPVDGAVSQCGPIKHGQIFQAKGHEYSSLALLGDRADDAKRFEDGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGELFSVNPLTAENVPGLFARNERVVAIFETEIGPMAMVLVGATIVASIETIWAGTVTPPTGKKVFTWDYPTEGPAALTLDKGAEMGRFKLGSTVVMLFAKDALDDFADDVTPKAVTRMGQPFAKIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI52</accession>
    <name>B1KI52_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anti-sigma-E factor RseA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Regulator of SigE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sigma-E anti-sigma factor RseA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sigma-E factor negative regulatory protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1238</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RseA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323876.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1238"/>
    <dbReference type="EnsemblBacteria" id="ACA85530">
        <property type="protein sequence ID" value="ACA85530"/>
        <property type="gene ID" value="Swoo_1238"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1238"/>
    <dbReference type="eggNOG" id="COG3073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108851_1_0_6"/>
    <dbReference type="OMA" id="PEWNIAE"/>
    <dbReference type="OrthoDB" id="1628369at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016989">
        <property type="term" value="F:sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16328">
        <property type="entry name" value="RseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005573">
        <property type="entry name" value="Anti-sigma_E_RseA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005572">
        <property type="entry name" value="Anti-sigma_E_RseA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036147">
        <property type="entry name" value="Anti-sigma_E_RseA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026279">
        <property type="entry name" value="RseA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03873">
        <property type="entry name" value="RseA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03872">
        <property type="entry name" value="RseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016938">
        <property type="entry name" value="RseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89069">
        <property type="entry name" value="SSF89069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="RseA_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="RseA_C" evidence="8">
        <location>
            <begin position="128"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="200" mass="21763" checksum="CA033B1F4F918196" modified="2008-04-29" version="1">MDKLGQEWVSAAVDGEVDEQALAELAANKDSHEQWRDYHMIGDAMRGELPKTMNLDLSASIAAAIELEPAILAPAQPKLEETQVAKKSNVIPMFKQFGQYAIAASVALVAVIGVQNYSQETAIDASPLPVLNTRPLVGSVTPVSLQTGPVQQNQGFSNVQMKEQRQRINAYIQDHMLQQRLNNGVKIEDNSGVDSIPVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIR9</accession>
    <name>B1KIR9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326892.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4312"/>
    <dbReference type="EnsemblBacteria" id="ACA88565">
        <property type="protein sequence ID" value="ACA88565"/>
        <property type="gene ID" value="Swoo_4312"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4312"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_521657_0_0_6"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="328"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="522" mass="58092" checksum="BECF9EA4875C1A24" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIS3</accession>
    <name>G6PI_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="1">GPI</shortName>
            <ecNumber evidence="1">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphoglucose isomerase</fullName>
            <shortName evidence="1">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phosphohexose isomerase</fullName>
            <shortName evidence="1">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pgi</name>
        <name type="ordered locus">Swoo_1279</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323917.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIS3"/>
    <dbReference type="SMR" id="B1KIS3"/>
    <dbReference type="STRING" id="392500.Swoo_1279"/>
    <dbReference type="EnsemblBacteria" id="ACA85571">
        <property type="protein sequence ID" value="ACA85571"/>
        <property type="gene ID" value="Swoo_1279"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1279"/>
    <dbReference type="eggNOG" id="COG0166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017947_3_1_6"/>
    <dbReference type="OMA" id="IGVWYIN"/>
    <dbReference type="OrthoDB" id="417261at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0312">Gluconeogenesis</keyword>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000125759" description="Glucose-6-phosphate isomerase">
        <location>
            <begin position="1"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <sequence length="545" mass="60002" checksum="9C40CE784487D683" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY3</accession>
    <name>B1KIY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323977.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1339"/>
    <dbReference type="EnsemblBacteria" id="ACA85631">
        <property type="protein sequence ID" value="ACA85631"/>
        <property type="gene ID" value="Swoo_1339"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1339"/>
    <dbReference type="eggNOG" id="ENOG5031HR1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2248280_0_0_6"/>
    <dbReference type="OMA" id="HRFIMPC"/>
    <dbReference type="OrthoDB" id="2023392at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="104" mass="11008" checksum="C36EA01817A85204" modified="2008-04-29" version="1">MLWFVAAFIIASGIFKFAPANVTSQTIAKSSQDGLSHVSLSVLPIVILTWLLITIFQGEGNSFGAASFGFIVTACSVALPRMHKFIIPCALLTSISLAIGVLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY8</accession>
    <name>B1KIY8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OmpA/MotB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1344</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323982.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1344"/>
    <dbReference type="EnsemblBacteria" id="ACA85636">
        <property type="protein sequence ID" value="ACA85636"/>
        <property type="gene ID" value="Swoo_1344"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1344"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016890_6_1_6"/>
    <dbReference type="OMA" id="IVYFEFA"/>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764541" evidence="2">
        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="75"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21091" checksum="C4A7C30DE1A0583F" modified="2008-04-29" version="1" precursor="true">MIKRAGVCFILSIGLLFCLSASAWTWTDSDGDGVPDAKDACPETKVGVIVRSNGCGVQVDTDRLCLPTLDEQFYPRTCTQATPLVLNFEFAQAEVMFAQWQVFTRIKRFLQEHDVKLCLLGHTDSVGAEAGNMALSHLRALNVKRILVDDLGFNPDRFQVKGMADTHPVASNDFPEGRAMNRRVELFVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ55</accession>
    <name>B1KJ55_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325411.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87075">
        <property type="protein sequence ID" value="ACA87075"/>
        <property type="gene ID" value="Swoo_2800"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2800"/>
    <dbReference type="eggNOG" id="ENOG5033HXQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168259_0_0_6"/>
    <dbReference type="OMA" id="MWWRVSW"/>
    <dbReference type="OrthoDB" id="1950380at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12696" checksum="60923253785517DE" modified="2008-04-29" version="1">MWWRVTIITLAYLLLGAHFLRYGQELICLAYASAPLVLFIKRVELTRLLQIVLAISAVLVWGVSSYDYVQMRIAMDAPWYRLSIIMSSVTVFTLLASLCCSGVIAKRTKISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ74</accession>
    <name>B1KJ74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325430.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2819"/>
    <dbReference type="EnsemblBacteria" id="ACA87094">
        <property type="protein sequence ID" value="ACA87094"/>
        <property type="gene ID" value="Swoo_2819"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2819"/>
    <dbReference type="eggNOG" id="COG1246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115862_3_1_6"/>
    <dbReference type="OMA" id="CIEYLWV"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="102" mass="11692" checksum="ABC4584816939BDB" modified="2008-04-29" version="1">MYLRDDAGQVIAGLTGKIFGGWLHVEFLWVDEAHRNKDYGAKILSEAENEAISKGCKASSLDTFSFQALNFYLKQGYEVVGELDGYYGTHRRHYLRKQLTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ84</accession>
    <name>B1KJ84_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2829</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325440.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87104">
        <property type="protein sequence ID" value="ACA87104"/>
        <property type="gene ID" value="Swoo_2829"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2829"/>
    <dbReference type="HOGENOM" id="CLU_2958216_0_0_6"/>
    <dbReference type="OMA" id="NNHLNDQ"/>
    <dbReference type="OrthoDB" id="2219654at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="59" mass="6926" checksum="BE29914224688E14" modified="2008-04-29" version="1">MESTKVRLRNDQNNHLNDQIEQFDDFAPVVRKPNTQLYSSLCEAFNSDEVTSIYIRGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD9</accession>
    <name>B1KJD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4358</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326937.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4358"/>
    <dbReference type="EnsemblBacteria" id="ACA88611">
        <property type="protein sequence ID" value="ACA88611"/>
        <property type="gene ID" value="Swoo_4358"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4358"/>
    <dbReference type="eggNOG" id="COG0578">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015740_5_1_6"/>
    <dbReference type="OMA" id="FAYSDCW"/>
    <dbReference type="OrthoDB" id="360065at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DAO" evidence="9">
        <location>
            <begin position="23"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="10">
        <location>
            <begin position="410"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="523" mass="58204" checksum="2A649D47C59D2EF9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJH5</accession>
    <name>B1KJH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase U62 modulator of DNA gyrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4395</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326973.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4395"/>
    <dbReference type="EnsemblBacteria" id="ACA88647">
        <property type="protein sequence ID" value="ACA88647"/>
        <property type="gene ID" value="Swoo_4395"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4395"/>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026425_1_0_6"/>
    <dbReference type="OMA" id="TDFWGSM"/>
    <dbReference type="OrthoDB" id="806701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="37"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="127"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="247"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="482" mass="50805" checksum="8FFF5E3ED1D5129B" modified="2008-04-29" version="1">MPFLTQVEQSLLQDGQSLSDLQGYLNIIHQHDVDFSDLYFQGSRHESWVLEDGIVKEGSFHIERGVGVRAITGEKTGFAYADEITPSALIASAEAARSIASAGANGSVQAWKSQEVKPLYQSADPIAAMEEVKKIALLKEADAYIRSLDSRIIQVVVSLSGVHEEILVAASDGTLAADIRPLVRFNCSVILEDEGKRERGASGGGGRHGYEALMETDDAGLPKCFSSAREAVRQAQVNLTAIDAPAGQMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGLVGQQVASKLVTVVDDGTIANRRGSLSIDDEGVVSQKTVLIQDGILKGYMQDKLNARLMGEQSTGNGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKNGIYAPNFGGGQVDITSGKFVFSASEAYLIENGEVTQAIKGATLIGNGPEAMGEISMVGNDLALDNGVGVCGKDGQSVPVGVGQPTLKLDSLTVGGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI0</accession>
    <name>B1KJI0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rod shape-determining protein MreD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MreD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326978.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4400"/>
    <dbReference type="EnsemblBacteria" id="ACA88652">
        <property type="protein sequence ID" value="ACA88652"/>
        <property type="gene ID" value="Swoo_4400"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4400"/>
    <dbReference type="eggNOG" id="COG2891">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119315_0_0_6"/>
    <dbReference type="OMA" id="YWAMALP"/>
    <dbReference type="OrthoDB" id="1451784at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007227">
        <property type="entry name" value="Cell_shape_determining_MreD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026034">
        <property type="entry name" value="MreD_proteobac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37484">
        <property type="entry name" value="PTHR37484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04093">
        <property type="entry name" value="MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018472">
        <property type="entry name" value="MreD_proteobac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03426">
        <property type="entry name" value="shape_MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="19172" checksum="F90B360FDF8D1213" modified="2008-04-29" version="1">MSMHIANGRWVVWLSFLVAMLFQIMPLPDLVEAWRPDWLLLVMIYWAMALPHRYNILSAWILGVMLDIMLGAHLGIRALSMSLVVYVVVLHFQRLRNFPMWQQALMVASLICLHHLVIFWVQFVVGTVTFDVSLFLPAISSLIIWPWVFWILRRVRRLYKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ3</accession>
    <name>B1KJQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1434</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324072.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1434"/>
    <dbReference type="EnsemblBacteria" id="ACA85726">
        <property type="protein sequence ID" value="ACA85726"/>
        <property type="gene ID" value="Swoo_1434"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1434"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012070_0_0_6"/>
    <dbReference type="OMA" id="DWWSIGN"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764578" evidence="6">
        <location>
            <begin position="21"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="53"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="408"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="753" mass="82250" checksum="E2DA9B31C8E7CDFC" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJU7</accession>
    <name>B1KJU7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325470.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2859"/>
    <dbReference type="EnsemblBacteria" id="ACA87134">
        <property type="protein sequence ID" value="ACA87134"/>
        <property type="gene ID" value="Swoo_2859"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2859"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_9_2_6"/>
    <dbReference type="OMA" id="MLEATYL"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd04629">
        <property type="entry name" value="CBS_pair_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044729">
        <property type="entry name" value="CBS_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="77"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="16162" checksum="14C0104A0A2BDACA" modified="2008-04-29" version="1">MESIKISSYMNRRPVTFTVDMHIAEAVEIFLRAKQIGGPVIDENNYVVGFLSEQDCLIKMLEATYLNESHYVVGDLMHDKPLTVRPDGSVLDLAQQMTHAKPKIYPIIDESNKLIGVITRSDVLKAIDDQLKAMYQDGHSRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKQ9</accession>
    <name>B1KKQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c biogenesis protein transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3005</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325612.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3005"/>
    <dbReference type="EnsemblBacteria" id="ACA87276">
        <property type="protein sequence ID" value="ACA87276"/>
        <property type="gene ID" value="Swoo_3005"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3005"/>
    <dbReference type="eggNOG" id="COG4232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014657_1_1_6"/>
    <dbReference type="OMA" id="FNQIYGP"/>
    <dbReference type="OrthoDB" id="1055204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02953">
        <property type="entry name" value="DsbDgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035671">
        <property type="entry name" value="DsbD_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028250">
        <property type="entry name" value="DsbDN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11412">
        <property type="entry name" value="DsbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764618" evidence="3">
        <location>
            <begin position="17"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC" evidence="5">
        <location>
            <begin position="46"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="4">
        <location>
            <begin position="294"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="683" mass="75007" checksum="754F4EB44D14E237" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKS2</accession>
    <name>B1KKS2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L3 glutamine methyltransferase</fullName>
            <shortName evidence="4">L3 MTase</shortName>
            <ecNumber evidence="4">2.1.1.298</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N5-glutamine methyltransferase PrmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prmB</name>
        <name evidence="6" type="ordered locus">Swoo_3018</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:45020"/>
            <dbReference type="Rhea" id="RHEA-COMP:11063"/>
            <dbReference type="Rhea" id="RHEA-COMP:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.298"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.298" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325625.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3018"/>
    <dbReference type="EnsemblBacteria" id="ACA87289">
        <property type="protein sequence ID" value="ACA87289"/>
        <property type="gene ID" value="Swoo_3018"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3018"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_5_1_6"/>
    <dbReference type="OMA" id="IYYGHGT"/>
    <dbReference type="OrthoDB" id="1816476at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02125">
        <property type="entry name" value="L3_methyltr_PrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017127">
        <property type="entry name" value="Ribosome_L3_Gln-N5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037167">
        <property type="entry name" value="Mtase_YfcB_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03533">
        <property type="entry name" value="L3_gln_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="5">
        <location>
            <begin position="131"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="314" mass="35320" checksum="0C506EDA51CAD73F" modified="2008-04-29" version="1">MDKIFVDEAVTELRTIGDMLRWSVSRFNDANIYYGHGTDNAWDEAIALVFHALHLPEEIGQQVIHSNLTSSEKHKIVELILRRVRERLPVPYLTNKAMFAGLQFYVDERVLVPRSPIAEMIANRFSPWLYNKPVNRVLDLCTGSACIAIACAYEFDEAEVDALDISEDALEVAQINIETLGVMDRVFPIESNLFSAIPKGPHYDLIVSNPPYVDAEDIDDMPEEYHHEPEIGLASGRDGLDLTKRILANAADYLTEDGLLVVEVGNSMVHLAEQFPDVPFTWVSFEHGGDGVFVLTRDQLLEHGSVFAIYKDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL19</accession>
    <name>B1KL19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Amino acid adenylation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327150.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88825">
        <property type="protein sequence ID" value="ACA88825"/>
        <property type="gene ID" value="Swoo_4575"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4575"/>
    <dbReference type="eggNOG" id="ENOG503386I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1223151_0_0_6"/>
    <dbReference type="OMA" id="RRWANEL"/>
    <dbReference type="OrthoDB" id="1840866at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="240" mass="28217" checksum="B8ED86B3A15EE3C9" modified="2008-04-29" version="1">MALFLSLSNSMCKMLKQPFERITDAEGNNPGVQPITTNANRVSWQGQVIQLTGRHWQPYDDGSWLVVFMESNSRYCMMTHYPLKPDWEQLQQDFYNQWKLHTVGCLRANGFIRNDDDGMQVLDNIEWYFDQTKVHVFRNLDRSIATHISEIQYYLRSLFDDYNPSCFDSEEAWELSHFINQQPKKVGGNRGKKHEFFPVDRFIHDILYRFGSGISPDDFLDVKPGDFPCPYPQKPMLKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL20</accession>
    <name>B1KL20_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4576"/>
    <dbReference type="EnsemblBacteria" id="ACA88826">
        <property type="protein sequence ID" value="ACA88826"/>
        <property type="gene ID" value="Swoo_4576"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4576"/>
    <dbReference type="eggNOG" id="COG5184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_308568_0_0_6"/>
    <dbReference type="OMA" id="HEYNDAT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764625" evidence="2">
        <location>
            <begin position="21"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="956" mass="103919" checksum="38644163C4F87A61" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL66</accession>
    <name>B1KL66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322756.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0106"/>
    <dbReference type="EnsemblBacteria" id="ACA84407">
        <property type="protein sequence ID" value="ACA84407"/>
        <property type="gene ID" value="Swoo_0106"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0106"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_7_1_6"/>
    <dbReference type="OMA" id="PAKFSHG"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="13576" checksum="245E52E04BC934DA" modified="2008-04-29" version="1">MKTVIHTENAPAAIGPYSQALAFDKLVFTSGQLPLDPATMAFVEGGIKEQAYQSLKNLKAVLEQAGAGTDTVLKTTCFLADMEDFVAFNEVYTEVFGTEAAPARSCVQAARLPKDALVEVEAIAFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL79</accession>
    <name>B1KL79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322769.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0119"/>
    <dbReference type="EnsemblBacteria" id="ACA84420">
        <property type="protein sequence ID" value="ACA84420"/>
        <property type="gene ID" value="Swoo_0119"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0119"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_6"/>
    <dbReference type="OMA" id="PDFFIAH"/>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="281" mass="31544" checksum="42909158CF2C419A" modified="2008-04-29" version="1">MTYEGYKTFNAKLEDSILTITFNFGSVNLQGLEMISDLNSLAMRLERDHEVKVVIFQSANPEIWVCHYDTNLLKDLSTKAVSRSEVELLDLQKVLDRISKLPQATIAKLEGFARGGGHEFALACDMRFAARGKYKFMQMEVAMGILPCGGGASRMARQTGLGRALEIILSARDFGADEAEAYGTINKALEPDEIDDYVKNLAQRIARFPAESINACKRAVYESIDQPIEEALKAEAYWLYQSTSKTAAIKRFTIADEQGLQHDIDNQRNWDDLVMKVQDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL81</accession>
    <name>B1KL81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glutathione-disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0121</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322771.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0121"/>
    <dbReference type="EnsemblBacteria" id="ACA84422">
        <property type="protein sequence ID" value="ACA84422"/>
        <property type="gene ID" value="Swoo_0121"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0121"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_2_2_6"/>
    <dbReference type="OMA" id="MSKHYDY"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="PTHR42737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0274">FAD</keyword>
    <keyword evidence="2 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="11">
        <location>
            <begin position="6"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="10">
        <location>
            <begin position="340"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="440"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="174"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="8">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA84422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="451" mass="48353" checksum="67129D948F6D68BF" modified="2008-04-29" version="1">MAQHFDYICLGAGSGGIASANRAAMRGAKVLLIEAKALGGTCVNVGCVPKKVMWYGAQVAEALHLYAKDYGFDVTVNKFDWNTLVASREAYIERIHGSYDRGLESNKVTLVRGYGRFVNERTIEVDGQEYTADHILIATGGSPSIPNIPGAEHGIDSDGFFALREQPKRVAVIGAGYIAVELAGVLHSLGSETQLFVRKHAPLRSFDPMLSEALMESMATDGPTLHTNSTPESVSKNADGSLTLKLENGESFEVDSLIWAIGRKPSTNNIGLENTQVKLNDRGYVVVDEQQNTTNPGIYCVGDIIEGGVELTPVAVKAGRLLSERLFNGMADAKMDYTLIPTVVFSHPAIGTMGLSEPEAVAQYGAENVKCYTSGFTSMYTAVTAHRQACKMKLVCAGPEETVVGIHGIGFAMDEILQGFGVAMKMGATKAQFDAVVAIHPTGAEEFVTMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI4</accession>
    <name>B1KLI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar hook-length control protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324255.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1623"/>
    <dbReference type="EnsemblBacteria" id="ACA85909">
        <property type="protein sequence ID" value="ACA85909"/>
        <property type="gene ID" value="Swoo_1623"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1623"/>
    <dbReference type="eggNOG" id="COG3144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033240_0_0_6"/>
    <dbReference type="OMA" id="LGHMMVR"/>
    <dbReference type="OrthoDB" id="1740242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021136">
        <property type="entry name" value="Flagellar_hook_control-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038610">
        <property type="entry name" value="FliK-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02120">
        <property type="entry name" value="Flg_hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_hook" evidence="2">
        <location>
            <begin position="419"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="544" mass="59126" checksum="56799EBA26C13DB7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLL4</accession>
    <name>B1KLL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325647.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3040"/>
    <dbReference type="EnsemblBacteria" id="ACA87311">
        <property type="protein sequence ID" value="ACA87311"/>
        <property type="gene ID" value="Swoo_3040"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3040"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_1_1_6"/>
    <dbReference type="OMA" id="GHRCRRF"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765025" evidence="1">
        <location>
            <begin position="31"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="42"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14079" checksum="E5FBB24523E3801B" modified="2008-04-29" version="1" precursor="true">MNIINKGFKVSSYFIVTLLLLLSISQSSLAADKNPQTAWSKIDAGALVVDVRTAQEFASGHLDNAINIPFEAIAEGLNKLNIDKEREIVLYCRSGRRSGIANDTLIEKGYTNTYNGGGYKMLSNHKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLN3</accession>
    <name>B1KLN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3059</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3059"/>
    <dbReference type="MEROPS" id="M23.011"/>
    <dbReference type="EnsemblBacteria" id="ACA87330">
        <property type="protein sequence ID" value="ACA87330"/>
        <property type="gene ID" value="Swoo_3059"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3059"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026846_0_0_6"/>
    <dbReference type="OMA" id="GPHVCYR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007340">
        <property type="entry name" value="Opacity-associatedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04225">
        <property type="entry name" value="OapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OapA" evidence="6">
        <location>
            <begin position="92"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Csd3_N2" evidence="7">
        <location>
            <begin position="176"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="5">
        <location>
            <begin position="310"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="438" mass="48807" checksum="EF1CF08785E11A30" modified="2008-04-29" version="1" precursor="true">MGLKLHTRRTSFFKMPQLNVLAASFSQKSNFNKRLLLGAGLLIGAAILWPSHQESLPQRVPVELDIDAILAQLTPSTPVEVQSSQPDYVKSIVSGDTLSGLFVDAGVDQQSMYHVLEADLDVLALDTLKPGNKISFWLDDKGELQKLELYFSAARQVVFSRFDDGDYKVDEINIDGIWQNRTVSGDIQGSFYLSAKRAGLNAAEIQRIESLLKEKLNFARDLRAGDTFSVLMNDQFIDGNATGSSDILGITIHRGRSDINAYQNSDGNFYDDQGRSLSRAFQRIPLQKNYRISSNFNRNRHHPVTGRVTHHNGTDFATPIGTKIVAPGDGIVSLVTKHRFAGTYVVIEHGNKYRTRYLHLSKALVHKGQRVSRGQVIALSGNTGRVTGPHLHYEFHVNGRPVNPMKANIPMASKLSSKEMSEFQQLVKIRQMMMGQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLN5</accession>
    <name>B1KLN5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nuclease SbcCD subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sbcD</name>
        <name evidence="10" type="ordered locus">Swoo_3061</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'-&gt;5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 7">Heterodimer of SbcC and SbcD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SbcD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325668.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3061"/>
    <dbReference type="EnsemblBacteria" id="ACA87332">
        <property type="protein sequence ID" value="ACA87332"/>
        <property type="gene ID" value="Swoo_3061"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3061"/>
    <dbReference type="eggNOG" id="COG0420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038045_0_1_6"/>
    <dbReference type="OMA" id="TSGNHDS"/>
    <dbReference type="OrthoDB" id="1831911at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004593">
        <property type="entry name" value="SbcD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026843">
        <property type="entry name" value="SbcD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12320">
        <property type="entry name" value="SbcD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00619">
        <property type="entry name" value="sbcd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="8">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="SbcD_C" evidence="9">
        <location>
            <begin position="267"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="381" mass="42408" checksum="99DFE7E3290FB13E" modified="2008-04-29" version="1" precursor="true">MKFIHTSDWHIGRQLHNQSLLEDQRHVLAQIVELAVTHEVDGVIIAGDIYDRSIPPANAVALLDEVVNRLVNELKIPVIMIAGNHDGHERLGFASRQMRESGLHIIGPLKPTLTPIVLKGDTGDAVFYGLPYADPATVRHLFESEVSTHEQAMVELLEQVHKHDSQGLPKVVISHCFLDGGSESESERPLSIGGADKISPSLFTPFSYTALGHLHGPQFKGEPQVRYSGSILKYSFSEQHQKKSVTLVELTAEGEASIELLPLTAMRDVRIIEGELDTLLEAGKADLHRDDYLMVRLLDKRAILDPMGKLREVYPNVLHLERTGLMANNSQLAIGRDQIKKGELDMFTDFFSQVSGEPMSEAQQTVMVDTIDELHKQERTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP8</accession>
    <name>B1KLP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325681.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3074"/>
    <dbReference type="EnsemblBacteria" id="ACA87345">
        <property type="protein sequence ID" value="ACA87345"/>
        <property type="gene ID" value="Swoo_3074"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3074"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038151_1_0_6"/>
    <dbReference type="OMA" id="YQMKLTA"/>
    <dbReference type="OrthoDB" id="626101at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767471" evidence="1">
        <location>
            <begin position="32"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="419" mass="46849" checksum="D59C02EFE7470065" modified="2008-04-29" version="1" precursor="true">MAKVSLKTTSIAAALLLSVGGSLSIVPSVSAAEKCPIDLRKSKAVGQSAAKKVGKSFAAYQEGNVDEAIAILLEVNAKNDFDKAYIDRMLGNFYAEKSQMGTAIKYLKKAVEADILGGVDHAATVRLYADLLIQEKKFKESIPQYYKWMEFTCKQDAQVYRRIGIAYSEQKNWKKVLEVADKGLSISDKPDKGLYQMKLTAYFNQKNYPAAVKVLETMVPLFQDDKRLWVQLAQFYLMTEDYTKSLATYDLAYMNGFLETAGNITRLTQLLAQKGSSYRAAQIFEKHLKSGLIKEDEKTLSILAGFYHNAKELKEGAYYYGKAAAVNNSGKFYLKQARLLTLEEKYKSAIPVLKKALDAGGVNAGEVQFELALAYLGTKQYKAAYQRCKLAAKDKKTARTAKSYLAYIEEKARIYKVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS4</accession>
    <name>B1KLS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage shock protein A, PspA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325707.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3100"/>
    <dbReference type="EnsemblBacteria" id="ACA87371">
        <property type="protein sequence ID" value="ACA87371"/>
        <property type="gene ID" value="Swoo_3100"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3100"/>
    <dbReference type="eggNOG" id="COG1842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056466_3_0_6"/>
    <dbReference type="OMA" id="MIFRAKA"/>
    <dbReference type="OrthoDB" id="941029at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014319">
        <property type="entry name" value="Phageshock_PspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02977">
        <property type="entry name" value="phageshock_pspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="47"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="25896" checksum="E47944811B78E658" modified="2008-04-29" version="1">MGIFSRFADIINSNISSLLDKAEDPEKMVRLIIQEMEDTLVEVRSTSAKVLAEKKELLRRIAKVQEQVQDWQSKAELALSKDREDLAKAALIEKQKATELAATLTQELVVVEEQITRLKDEVNLLQEKLADAKARQKTIIMRKQTASSRLEVKKQLDSSKIDNAMNKFEQYERRVESLESQVDAYDLGNQKNLNDEFAALEAEDSVSAELEALKAKVSANKSKAKTKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLU5</accession>
    <name>B1KLU5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutaminyl-tRNA synthetase</fullName>
            <shortName evidence="9">GlnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glnS</name>
        <name evidence="13" type="ordered locus">Swoo_3121</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325728.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3121"/>
    <dbReference type="EnsemblBacteria" id="ACA87392">
        <property type="protein sequence ID" value="ACA87392"/>
        <property type="gene ID" value="Swoo_3121"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3121"/>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_2_3_6"/>
    <dbReference type="OMA" id="INNFCAQ"/>
    <dbReference type="OrthoDB" id="142899at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00126">
        <property type="entry name" value="Gln_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022861">
        <property type="entry name" value="Gln_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="30"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="12">
        <location>
            <begin position="345"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="273"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="37"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="43"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="266"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="274"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="556" mass="64056" checksum="F02CDB64360B1F32" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW4</accession>
    <name>B1KLW4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ketoacyl_synth_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327169.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4594"/>
    <dbReference type="EnsemblBacteria" id="ACA88844">
        <property type="protein sequence ID" value="ACA88844"/>
        <property type="gene ID" value="Swoo_4594"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4594"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086378_0_0_6"/>
    <dbReference type="OMA" id="MMRRRMS"/>
    <dbReference type="OrthoDB" id="1273274at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13723">
        <property type="entry name" value="Ketoacyl-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoacyl_synth_N" evidence="1">
        <location>
            <begin position="23"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="242" mass="26707" checksum="81BE6490E131EE26" modified="2008-04-29" version="1">MQLTFNICSWGAWSPQYQQAEDWKHWLESAPIQEELPHSPKLAQVPAMQRRRYSKLTKMQLEAAFQCDAPTPCRSIFASRHGELNRTLGLLDNLVEQEPLSPTAFSQSVHNTASGIYSILKGDQSSSTSIAASEETLLQSFIEAYGQLHQDPAPLMLVFGDEPVPEIYSQFTDETGLPVSMAFVLSPINNASSNATLSISYCDNEALASTQALSYGALLHGLANQRNVSGTLSNHLWKLSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC8</accession>
    <name>B1KMC8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Formate-dependent nitrite reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0240</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322890.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0240"/>
    <dbReference type="EnsemblBacteria" id="ACA84541">
        <property type="protein sequence ID" value="ACA84541"/>
        <property type="gene ID" value="Swoo_0240"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0240"/>
    <dbReference type="eggNOG" id="COG3303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104606_1_0_6"/>
    <dbReference type="OMA" id="NIGPDHR"/>
    <dbReference type="OrthoDB" id="1683334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012286">
        <property type="entry name" value="Tetrahaem_cytochrome"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14537">
        <property type="entry name" value="Cytochrom_c3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrom_c3_2" evidence="7">
        <location>
            <begin position="59"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="157" mass="17623" checksum="848B311CC013B634" modified="2008-04-29" version="1" precursor="true">MSSLFKYSVFLLLSVFSLVLMLSVSTNLIAAELNINKSKECIKCHKRNGMMRGVHGNDALDIRCQDCHGEKQGHPRQASNLIGFSDSSAVKPRTQVQACLQCHDHFRLFEHDWSHAVHSDKVNCASCHQLHSTTDSMVDLLATKRSQLCSRCHSVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMF8</accession>
    <name>B1KMF8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DegT/DnrJ/EryC1/StrS aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324302.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1670"/>
    <dbReference type="EnsemblBacteria" id="ACA85956">
        <property type="protein sequence ID" value="ACA85956"/>
        <property type="gene ID" value="Swoo_1670"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1670"/>
    <dbReference type="eggNOG" id="COG0399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033332_7_2_6"/>
    <dbReference type="OMA" id="PWPSFTQ"/>
    <dbReference type="OrthoDB" id="1722208at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="391" mass="43135" checksum="A9EB54845A4CBD33" modified="2008-04-29" version="1">MLNTPFSPWPSFTQEEADAISRVLLSNKVNYWTGSECREFEKEFAAWSGCKHAIALSNGTLALDLALKALNVADGDEVITTPRTFLASASSIVTAGASPVFADVDLNSQAITAESIEAVLTEKTKAVIVVHLAGMPAEMDAIMALSAKHGFYVIEDCAQAHGAKYKGRSVGSIGHIGAWSFCQDKIMTTGGEGGMVTTNDKALWQEMWSYKDHGKSFDAIYNREHPPGFRWLHDSFGTNWRMTELQGVLGRIQLGRMKGWTVARQTNGKAIDEAVSDLAVVRGVDVPEHIEHAEYKHYLFVCPQYLKEGWTRDLIVETINSKGVPAYQGSCSEVYLEKAFDNTSWRPSKRLPNAVELGETSLMFLVHPTLTQVEIDKTCEVIRSVLLLAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI9</accession>
    <name>B1KMI9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver modulated serine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324333.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1702"/>
    <dbReference type="EnsemblBacteria" id="ACA85987">
        <property type="protein sequence ID" value="ACA85987"/>
        <property type="gene ID" value="Swoo_1702"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1702"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_43_7_6"/>
    <dbReference type="OMA" id="VELRIAW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="14"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="460" mass="51859" checksum="834B869EB2AC21F3" modified="2008-04-29" version="1">MVDSLFKFQTENLNILIVEDTQSERCFIAQLLQNMGLHVNSCSSAEQAILEYERQEVDIVISDWRMPGITGPELCEHLKSLPFPPYIILLTSNNLAEHMIQGIESGADDFISKPFVPNVLKVRILAAARIVKLQRKLTHKNSELNTALANEHECLKQIQSDMKSAVKLQSSHLPSSSHLINQWHLATRFNPAQELAGDIFQCIEIDKTHIGFYLLDVTGHGIAASMQSFTLAQQLSCNSCDWESLDPALIVNKLNQDFEDPENKGRFATLILGIANSLTGEIRITVAGHPQPILLDDTGARLMELDSGLPLGIDRQFSYRYSKFTLKSHQHLMLYSDGLYESMHPRFGEFGITRLVKRCDQAHSLSPESLLHHLSHSINLWQQKKPQDDISMMLLSAPSLFKQSPMLDSTPVKELYYSHVETEDRTFKNEAVINEVLPVHPLSKASITSASDCISRRIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ7</accession>
    <name>B1KMQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Choline/carnitine/betaine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325771.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3164"/>
    <dbReference type="EnsemblBacteria" id="ACA87435">
        <property type="protein sequence ID" value="ACA87435"/>
        <property type="gene ID" value="Swoo_3164"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3164"/>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010118_3_1_6"/>
    <dbReference type="OMA" id="VHAWAIY"/>
    <dbReference type="OrthoDB" id="1217683at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018093">
        <property type="entry name" value="BCCT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00842">
        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01303">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="660" mass="73194" checksum="4740F6D8CAA06D14" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMR5</accession>
    <name>B1KMR5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325779.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3172"/>
    <dbReference type="EnsemblBacteria" id="ACA87443">
        <property type="protein sequence ID" value="ACA87443"/>
        <property type="gene ID" value="Swoo_3172"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3172"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_22_0_6"/>
    <dbReference type="OMA" id="LYIERWP"/>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="166" mass="19450" checksum="BA7E7E37D8BAABD1" modified="2008-04-29" version="1">MDGLQLTSLELKAHSEADLPFLLQLYTSVRRDEFAAANWPESQLNLFLSEQFSAQYRYYCQHYSTDRFDIIYYQNQAVGRLFVDYWLDENQEIRIVDISLMPEYRGIGIASCLLEQLFIEAETLGLTVSIHVERNNPARALYERLGFKLKTQTDEVYLLMEWQAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMR8</accession>
    <name>B1KMR8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325782.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3175"/>
    <dbReference type="EnsemblBacteria" id="ACA87446">
        <property type="protein sequence ID" value="ACA87446"/>
        <property type="gene ID" value="Swoo_3175"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3175"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136176_1_0_6"/>
    <dbReference type="OMA" id="WHQHPVI"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767216" evidence="1">
        <location>
            <begin position="19"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="51"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="14809" checksum="22112CE5161B65C8" modified="2008-04-29" version="1" precursor="true">MLKPLYSLLLMGAFSATAATSKDLIKSTETWDGQTLPQYSLVQPEVTIKEIVIAPGEQLPWHQHPAINAGILLSGELIVYTRDGKEKNLKAGEPLIELFNTSHYGKNISSEPAKIVVFYLAEKDAAVTVLDKEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV0</accession>
    <name>B1KMV0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3208"/>
    <dbReference type="EnsemblBacteria" id="ACA87478">
        <property type="protein sequence ID" value="ACA87478"/>
        <property type="gene ID" value="Swoo_3208"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3208"/>
    <dbReference type="eggNOG" id="COG3575">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092842_1_0_6"/>
    <dbReference type="OMA" id="VWDKLHG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009267">
        <property type="entry name" value="NTP_transf_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39166">
        <property type="entry name" value="PTHR39166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06042">
        <property type="entry name" value="NTP_transf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="21790" checksum="25076D4AB0A7C446" modified="2008-04-29" version="1">MTQARKNGQDLFSHELTLIDWIMKDPIRMRALTLIRDLNLPQGMIAAGFVRNLVWDRLHGYEQGRALTDIDVIYFEPNDTSVEADKAYEMKLKALAPELPWSVKNQARMHIRNGDPSYGSSLDAMSYWPEQETAVGVYLQQELTVVSAFGFDSLFLLKLTPNPKRDFELFEARVAQKSWLTYYPKLEIS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX3</accession>
    <name>RL14_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplN</name>
        <name type="ordered locus">Swoo_4680</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327253.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMX3"/>
    <dbReference type="SMR" id="B1KMX3"/>
    <dbReference type="STRING" id="392500.Swoo_4680"/>
    <dbReference type="EnsemblBacteria" id="ACA88930">
        <property type="protein sequence ID" value="ACA88930"/>
        <property type="gene ID" value="Swoo_4680"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4680"/>
    <dbReference type="eggNOG" id="COG0093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095071_2_1_6"/>
    <dbReference type="OMA" id="AKEVLCI"/>
    <dbReference type="OrthoDB" id="1799923at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000144330" description="50S ribosomal protein L14">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <sequence length="122" mass="13303" checksum="BC3910F69BF26DC4" modified="2008-04-29" version="1">MIQMQSTLDVACNSGARRVQCIKVLGGSHRRYAGIGDIIKVSVKEAIPRGKAKKGDVYSAVVVRTKKGVRRPDGSVIRFDRNAAVLLNANNAPIGTRIFGPVTRELRTEQFMKIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN16</accession>
    <name>B1KN16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327290.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88973">
        <property type="protein sequence ID" value="ACA88973"/>
        <property type="gene ID" value="Swoo_4723"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4723"/>
    <dbReference type="eggNOG" id="ENOG5030QJ6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1694012_0_0_6"/>
    <dbReference type="OMA" id="LGAHTEY"/>
    <dbReference type="OrthoDB" id="1591841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767223" evidence="1">
        <location>
            <begin position="20"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17658" checksum="02784BAEE082B2AE" modified="2008-04-29" version="1" precursor="true">MFKWITLSLSFFFSTLVLANSTEVKLEHFAKNYFDLWVATQAPDASKEDIENYLALLTQDIGHQHLPYDSDDIRQPDGKENMRKGMLYYLGGHTEHSATLISITVGYNVVIIKYDTVSKGIHPQTKTEVRFSYDTTEVLEIENGKVSVIRKYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN22</accession>
    <name>B1KN22_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type II secretion system protein I</fullName>
            <shortName evidence="6">T2SS minor pseudopilin I</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4729</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell inner membrane</location>
            <topology evidence="2 6">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Cleaved by prepilin peptidase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the GSP I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4729"/>
    <dbReference type="EnsemblBacteria" id="ACA88979">
        <property type="protein sequence ID" value="ACA88979"/>
        <property type="gene ID" value="Swoo_4729"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4729"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121289_6_0_6"/>
    <dbReference type="OMA" id="RTWYWQQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003413">
        <property type="entry name" value="T2SS_GspI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010052">
        <property type="entry name" value="T2SS_protein-GspI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38779">
        <property type="entry name" value="PTHR38779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02501">
        <property type="entry name" value="T2SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01707">
        <property type="entry name" value="gspI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0488">Methylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SSI" evidence="7">
        <location>
            <begin position="56"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15681" checksum="0FC2A75B1ED9AC0D" modified="2008-04-29" version="1" precursor="true">MVSMSTNIRSSIGSSRSRKAKGMTLLEVIVALAVFSIAAVSITKSLGEQMANMPILEQRTYAQWVADNVMVDARLEAKFPDLGKKDGQAELAGKEWYWRKEVVKTTDDKFRMIRVSVSDDERYERIVAQVSSYVLNQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN32</accession>
    <name>B1KN32_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 7">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4739</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H(+) + L-glutamate = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327306.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4739"/>
    <dbReference type="EnsemblBacteria" id="ACA88989">
        <property type="protein sequence ID" value="ACA88989"/>
        <property type="gene ID" value="Swoo_4739"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4739"/>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019582_2_2_6"/>
    <dbReference type="OMA" id="TMAPHSE"/>
    <dbReference type="OrthoDB" id="1478871at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006536">
        <property type="term" value="P:glutamate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="PTHR43321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="464" mass="52582" checksum="FAEBB2155FC86A3F" modified="2008-04-29" version="1">MPLHSKDTVRDDLLDDIYSSADLALSMPKYKMPEQEHDSRHVYQVIHDELMMDGNSRQNLATFCQTWVEDEVHKLMDECIDKNMIDKDEYPQTAELEARCVHMLADLWHSPDAENTLGCSTTGSSEAAMLGGMALKWAWREKMRKLGKPTDKPNLICGPVQVCWHKFARYWDIELREIPMEGDRLIMTPEEVIKRCDENTIGVVPTLGVTFTCQYEPVKAVHEALDQLQKDTGLDIPMHIDAASGGFLAPFCDPDLEWDFRLPRVKSINASGHKFGLSPLGVGWVIWRDASALDKDLIFNVNYLGGNMPTFALNFSRPGGQIVAQYYNFLRLGREGYRKIHQACYDTAIYLSGEIEKMGMFDIIYDGQGGIPAMSWSLKEGVEPGFNLFDLSDRIRSRGWQIAAYAMPPKREDLVIMRILVRHGFSRDQADLLVADLQHCVDFFAKHPISHSSDEAESAGFNHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN70</accession>
    <name>B1KN70_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322916.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0266"/>
    <dbReference type="EnsemblBacteria" id="ACA84567">
        <property type="protein sequence ID" value="ACA84567"/>
        <property type="gene ID" value="Swoo_0266"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0266"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_933322_0_0_6"/>
    <dbReference type="OrthoDB" id="1193719at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="48"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="277" mass="32644" checksum="33026CC4F94E9D23" modified="2008-04-29" version="1">MDFYSESNINRYEVSKLYGLASEYNKISNFCKLVWSSLWSEKKDLYKFAPSIMLYGSPGTGKTTLLKNVAYSLKDDNLKYVTLSLELMLDKDLGMSSKRLRDFFEHIKSLALQDYKVFVHFDDVDSVLCSRYISNESSGVKRFVNTFIKEIDYLLDVECDYLPIILITTNMFSMIDTAVKRRFSLKFEIENRVSVEEFRNWIYPMCDDLKIKNELNYELLYKLMNEKELTNFDVYLILQELFLEQLTGIKVTGLNLVQKFEEAKSSKSDFERQRKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB9</accession>
    <name>B1KNB9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_0315</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322965.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0315"/>
    <dbReference type="EnsemblBacteria" id="ACA84616">
        <property type="protein sequence ID" value="ACA84616"/>
        <property type="gene ID" value="Swoo_0315"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0315"/>
    <dbReference type="eggNOG" id="COG0157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039622_0_3_6"/>
    <dbReference type="OMA" id="DMIMLKD"/>
    <dbReference type="OrthoDB" id="1718114at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="124"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="145"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="257"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="278"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA84616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="32221" checksum="3CD29CA1F7D1246D" modified="2008-04-29" version="1">MLENDIRLAVKVALEEDLGYQDESSSSSEQAQERASADITAQLIPADRHAQASLITREEGVFCGKAWAEQVFNQLGGEVALHWHVDDGDLLVPNQVLCEFSGPARAILTGERTAMNFIQTLSGVATLTKQYTDRIATTNTRLLDTRKTIPGLRTAQKYAVTCGGGKNHRIGLFDAFLIKENHIMACGGIAQAISKARELQPDKLVEVEVESILELQQALEAGSDIIMLDNFDVTMMIAAVELNKRLPDAQQAKLEVSGNVTLETIGDFAKTGVDYISVGALTKHVKALDLSLRLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNM0</accession>
    <name>B1KNM0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipoprotein releasing system, transmembrane protein, LolC/E family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1813</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1813"/>
    <dbReference type="EnsemblBacteria" id="ACA86097">
        <property type="protein sequence ID" value="ACA86097"/>
        <property type="gene ID" value="Swoo_1813"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1813"/>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_1_6"/>
    <dbReference type="OMA" id="GWWQQNG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011925">
        <property type="entry name" value="LolCE_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02212">
        <property type="entry name" value="lolCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="10">
        <location>
            <begin position="33"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="311"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="416" mass="45291" checksum="01050129ED0FE85A" modified="2008-04-29" version="1">MSRWATMNFALSAHIGFRYWRARKANAFASFITFFAVSGILLGVAALIIVSSVMNGLEGQLKQRILGAVPQLTVNSEQALTHWHANVAELKTLPGVLAATPSIATQAMVQSPSNISAIQVYGIYPEYEKVLEGKMQGVLNAHFSQLIPGKYRIILGSELARRLDVSIGEKVRVLSAEGVVYSPFGPVPSQRKFVVAGIFEMGSQVDASLAYVHYEDAQRLMRQPPGEIKHLRLYLADPFNAESLSSEVTNLFKRQGIEVTTSDWRDTYGHLFSAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKTTDVAVLKTQGLSTANVMGIFIFQGSLNAIIGLVLGLIIGVGLTLNLNTMMNSVGISILGAGQSLPVQIEWSQMSWIVIGTLVITFCATLYPAFRAAKVQPATALRYE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNM8</accession>
    <name>Y1821_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0434 protein Swoo_1821</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1821</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0434 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNM8"/>
    <dbReference type="SMR" id="B1KNM8"/>
    <dbReference type="STRING" id="392500.Swoo_1821"/>
    <dbReference type="EnsemblBacteria" id="ACA86105">
        <property type="protein sequence ID" value="ACA86105"/>
        <property type="gene ID" value="Swoo_1821"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1821"/>
    <dbReference type="eggNOG" id="COG2835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155659_3_1_6"/>
    <dbReference type="OMA" id="ELICHAD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01187">
        <property type="entry name" value="UPF0434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000138336" description="UPF0434 protein Swoo_1821">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01187"/>
        </source>
    </evidence>
    <sequence length="58" mass="6596" checksum="2FEC2365CCB24655" modified="2008-04-29" version="1">MSFDKKLLEIVACPVCKGKLDYDKAKQQLICKLDRLAYPINDGIPVLLENKAESWEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU1</accession>
    <name>B1KNU1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ordered locus">Swoo_3279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Allosterically activated by GTP. Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325885.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3279"/>
    <dbReference type="EnsemblBacteria" id="ACA87549">
        <property type="protein sequence ID" value="ACA87549"/>
        <property type="gene ID" value="Swoo_3279"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3279"/>
    <dbReference type="eggNOG" id="COG0528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033861_0_0_6"/>
    <dbReference type="OMA" id="PIIVFDM"/>
    <dbReference type="OrthoDB" id="1043239at2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="11"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in allosteric activation by GTP" evidence="6">
        <location>
            <begin position="23"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="15"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="138"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="26628" checksum="390421A87AAD1D89" modified="2008-04-29" version="1">MSTNPKPAFRRILLKLSGEALMGEEGFGIDPKVLDRMAQEIKELVELGIQVGVVIGGGNLFRGEGLAQAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVLKGTKVDGVYSDDPVKNPDAVKYDEMGYDEVLEKELKVMDLAAFTMARDHDMPLLVFNMNKPGALRRVIMGEHEGTMIRASRPE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP09</accession>
    <name>MOAC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="1">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">moaC</name>
        <name type="ordered locus">Swoo_4791</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MoaC family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327357.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP09"/>
    <dbReference type="SMR" id="B1KP09"/>
    <dbReference type="STRING" id="392500.Swoo_4791"/>
    <dbReference type="EnsemblBacteria" id="ACA89040">
        <property type="protein sequence ID" value="ACA89040"/>
        <property type="gene ID" value="Swoo_4791"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4791"/>
    <dbReference type="eggNOG" id="COG0315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074693_1_1_6"/>
    <dbReference type="OMA" id="IWDMVKS"/>
    <dbReference type="OrthoDB" id="1595361at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000139298" description="Cyclic pyranopterin monophosphate synthase">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <sequence length="158" mass="17178" checksum="FC883E487764E8A1" modified="2008-04-29" version="1">MSNEFTHINADGNAHMVDVTEKAVTEREARAEAFIEMAPATLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLMLTKVEVELEAQPEHSRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQTRLLEKRGGKSGHFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP52</accession>
    <name>B1KP52_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4834</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327400.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4834"/>
    <dbReference type="EnsemblBacteria" id="ACA89083">
        <property type="protein sequence ID" value="ACA89083"/>
        <property type="gene ID" value="Swoo_4834"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4834"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045354_1_0_6"/>
    <dbReference type="OMA" id="PTWRLMS"/>
    <dbReference type="OrthoDB" id="1597438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071470">
        <property type="term" value="P:cellular response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030192">
        <property type="entry name" value="YbdG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30414">
        <property type="entry name" value="PTHR30414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="421" mass="47512" checksum="83E75508C19DFC85" modified="2008-04-29" version="1">MDQELRLRISKWLSDWGVNSTPSDDVSTSLLVVVSLVLAIIAYLFVRRGVVRAMNIVIHRSKVSWDDIFMRHKVLEKFSYVVPALVMNLLIPLALKEHQLISSLVDRLLSVWIVVMLVRAIYSALDAVNEIADVNLVSRRLPIKSFVQLFKLFLFFVAIIISISVLANQSPVYFLSGLGVATGLVMLVFRDTILGFVAGIQLAANRMVSTGDWIQMDKYGANGSVVEVSLTTVKVQNWDNTLTMIPAYALVSDAFKNWRGMSESGGRRIKRAVSIDIHSIHFLSEEEQVKLSKINCLKEYFSSKREEISLFNQGVEDADMPVNSRHLTNIGTFRAYLIEYVTRHPLIHNDMTLLVRQLAPTSEGVPIEVYVFTTDIRWNNYEDIQGDIFDHIFAILPEFGLKVFQGPTGSDIRSLKGEVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPR5</accession>
    <name>B1KPR5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3329</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3329"/>
    <dbReference type="EnsemblBacteria" id="ACA87598">
        <property type="protein sequence ID" value="ACA87598"/>
        <property type="gene ID" value="Swoo_3329"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3329"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_1_6"/>
    <dbReference type="OMA" id="AQIYGIP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046942">
        <property type="term" value="P:carboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00713">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="426" mass="45167" checksum="4600A256F702F0B4" modified="2008-04-29" version="1" precursor="true">MWQTIKQIPFWQKVLAGFILGASIGVIFGESATVLKPLGDLFISAIKMLVAPLVFCAIVVSITSLGSQVSLKRLSFKTLAMFMFTGTLASLIGLTVGSLIDMGGSMELVATEVRERHVPEFAQVLLDMIPVNPFASLAEGKVLQIIVFAALVGIAINKVGEKAVPLKQAFEAGAEVMFQLTRMVLQLTPIGVFGLMAWVVGEYGLSTLLPLGKFIAAIYIAALIHIIFVYGGLIKFAAKLSPLQFFRKAMPAQLVAFTTASSFGTLPASTRCTESMGVSKQYGAFVLPLGATMNMDGCGGIYPAIAAIFIAQIYGIPLDMTDYMLIAVTATVASVGTAGVPGSAMVMLSVTLGVVGLPLEGIAFIAAIDRIIDMIRTSTNVTGDMMTAVVIGKSEGQLDEQQFYNDQEADTIEESQQATTQSKSVS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT1</accession>
    <name>SURE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="1">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">surE</name>
        <name type="ordered locus">Swoo_3345</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="1">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325949.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPT1"/>
    <dbReference type="SMR" id="B1KPT1"/>
    <dbReference type="STRING" id="392500.Swoo_3345"/>
    <dbReference type="PRIDE" id="B1KPT1"/>
    <dbReference type="EnsemblBacteria" id="ACA87614">
        <property type="protein sequence ID" value="ACA87614"/>
        <property type="gene ID" value="Swoo_3345"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3345"/>
    <dbReference type="eggNOG" id="COG0496">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045192_1_2_6"/>
    <dbReference type="OMA" id="DCVHIAL"/>
    <dbReference type="OrthoDB" id="1909278at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000092037" description="5'-nucleotidase SurE">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <sequence length="249" mass="26352" checksum="6A3757C2EBD7D8E7" modified="2008-04-29" version="1">MIKILVSNDDGVTAPGIVALTNALASSYDVMTVGPDRNCSGASNSLTLTNPLRINTLSNGYVSVSGTPTDCVHLAIRELYTDEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGLPAIAVSLVGSKLKHYDSAAFFTSKIIKGLLESPVAQDQILNINVPDLPVEQIKGIKVTRLGARHKAAGMLKTQDPAGRDIFWLGPPGEEQDASEGTDFHAVTNGYVSVTPLTVDLTAFNQITSMKEWIDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT9</accession>
    <name>B1KPT9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">(P)ppGpp synthetase I, SpoT/RelA</fullName>
            <ecNumber evidence="5">2.7.6.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325957.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3353"/>
    <dbReference type="EnsemblBacteria" id="ACA87622">
        <property type="protein sequence ID" value="ACA87622"/>
        <property type="gene ID" value="Swoo_3353"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3353"/>
    <dbReference type="eggNOG" id="COG0317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012300_3_0_6"/>
    <dbReference type="OMA" id="TEIGHNC"/>
    <dbReference type="OrthoDB" id="204079at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="402"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="3">
        <location>
            <begin position="662"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="735" mass="83362" checksum="314B2DD8E3919AC4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPV8</accession>
    <name>B1KPV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3372"/>
    <dbReference type="EnsemblBacteria" id="ACA87641">
        <property type="protein sequence ID" value="ACA87641"/>
        <property type="gene ID" value="Swoo_3372"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3372"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_1_0_6"/>
    <dbReference type="OMA" id="GTQRLDW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="202" mass="23117" checksum="D77781D5CC13B744" modified="2008-04-29" version="1">MHTSTRFTPHPITLESKDIQLRPLTREDVAGFQLAGNHEKLWQWVVPNPCKSLEMTAAWIEKALVEQELGNQVPFVIIDKQSQKVIGSTRYCSIRRDDRNIEIGHTFITPEFQRSHVNTQAKYLLLQHGFEVLDAIRVEIKTHAKNEQSRSAILRIGAEFEGILRNSRILPGGSYRNTAIYSIIEQDWPQVKSVLQGKMEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPZ2</accession>
    <name>B1KPZ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327422.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4856"/>
    <dbReference type="EnsemblBacteria" id="ACA89105">
        <property type="protein sequence ID" value="ACA89105"/>
        <property type="gene ID" value="Swoo_4856"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4856"/>
    <dbReference type="eggNOG" id="COG2856">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066427_1_0_6"/>
    <dbReference type="OMA" id="ECWIYGS"/>
    <dbReference type="OrthoDB" id="1938768at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025644">
        <property type="entry name" value="DUF4344"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14247">
        <property type="entry name" value="DUF4344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766939" evidence="1">
        <location>
            <begin position="24"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="29232" checksum="2880EE621E3E8AB8" modified="2008-04-29" version="1" precursor="true">MKNIFIIISVLCVVISLSSQASAKTTQIYLPVKNSADKQAREVIKSVEAQILQLVGELPINSNLEIRYGAKDGPLFDPESMRIEIPYEFVTEVLKRFEKDNYQETGVMPYEATQDALLHTLGHEYGHAFIFANQVIVLGREEDAVDTLATLLLLHTFENGTDIALSAADLFSLEDEEVQEFVDDHFWGEHSLDAQRYFSTLCLIYGSDPERYVDLIPRDQIYIQRDSYCEEEYFRQAENWERLKSRYRVSSPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ46</accession>
    <name>B1KQ46_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flavodoxin/nitric oxide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4910"/>
    <dbReference type="EnsemblBacteria" id="ACA89159">
        <property type="protein sequence ID" value="ACA89159"/>
        <property type="gene ID" value="Swoo_4910"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4910"/>
    <dbReference type="eggNOG" id="COG0716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051402_4_1_6"/>
    <dbReference type="OMA" id="ACFGSGD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="4">
        <location>
            <begin position="8"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="150" mass="16499" checksum="B2FE25DE17972B43" modified="2008-04-29" version="1">MRVPMSKIEILIGTTLGNAEYVADEIAAQLSGLGHENQLHMAPKLQDLDTESLWLIVSSTHGAGDLPDNLAPFLSEIFAKNPDLSKTKFAICAIGDSSYDTFCEGPEKLAQAMQDCGAQVYVDKIQIDVQYDSIPEDPALTWLSQWQDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ80</accession>
    <name>B1KQ80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional antiterminator, Rof</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323084.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0437"/>
    <dbReference type="EnsemblBacteria" id="ACA84735">
        <property type="protein sequence ID" value="ACA84735"/>
        <property type="gene ID" value="Swoo_0437"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0437"/>
    <dbReference type="eggNOG" id="COG4568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176324_1_0_6"/>
    <dbReference type="OMA" id="DYIEVAC"/>
    <dbReference type="OrthoDB" id="1884881at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009778">
        <property type="entry name" value="ROF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038626">
        <property type="entry name" value="Rof-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07073">
        <property type="entry name" value="ROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="SSF101744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="81" mass="9107" checksum="78A93B692FA92655" modified="2008-04-29" version="1">MIKCDIYDYIEVACLYKIEVLLTLHSGEEVKGVADTTSINGDKQEFLVIKQGTETLNIELVSIKNMKALTPNPHFSSLDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQF3</accession>
    <name>B1KQF3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323156.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0511"/>
    <dbReference type="EnsemblBacteria" id="ACA84808">
        <property type="protein sequence ID" value="ACA84808"/>
        <property type="gene ID" value="Swoo_0511"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0511"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_4_6"/>
    <dbReference type="OMA" id="LWLICPS"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="33764" checksum="5F1AB8128D23A148" modified="2008-04-29" version="1">MQINDLKLFVRVADCGSITAAATELDISPASASAALKRLEKQLETSLFIRSTRSLRLTDTGERYLIHCRKALADLTLGQQAIDDVKEKISGVVKLALPSDVGRNVLLPWLDSFMDEYPELKLKVHIGDTLSDFYHDKIDMALRSGTPRDSSLVAFKICSASRVLCASPDYIAKWGKVESIDQLADHNCLFFMLDERTHDQWSFTQQGRQFKVRVTGNRSCNDADITRRWAVAGKGIVYKSSLDLGEDIAKGNLVPMLTDYQGEAADLYLVCPGREHVTPVMLLLRDMLRQRCKQRLEESHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ6</accession>
    <name>B1KQJ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5'-nucleotidase</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1951</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324581.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1951"/>
    <dbReference type="EnsemblBacteria" id="ACA86235">
        <property type="protein sequence ID" value="ACA86235"/>
        <property type="gene ID" value="Swoo_1951"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1951"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_7_0_6"/>
    <dbReference type="OMA" id="IYEAGSF"/>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005122595" evidence="2">
        <location>
            <begin position="20"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="44"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="4">
        <location>
            <begin position="373"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="588" mass="63971" checksum="D7EF22F44998838A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM6</accession>
    <name>B1KQM6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="8" type="ordered locus">Swoo_1981</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324611.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1981"/>
    <dbReference type="EnsemblBacteria" id="ACA86265">
        <property type="protein sequence ID" value="ACA86265"/>
        <property type="gene ID" value="Swoo_1981"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1981"/>
    <dbReference type="eggNOG" id="COG1559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025574_0_2_6"/>
    <dbReference type="OMA" id="IAMPGKA"/>
    <dbReference type="OrthoDB" id="708179at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="335" mass="37605" checksum="8951F47F92A5ECFB" modified="2008-04-29" version="1" precursor="true">MKKFIIAFTAAIFTLLTLAGGVSLWTYNTVVDFSQSTLKLEQAQDIELKRGTSFYQLVSLLEQRALISDGWKLKILVKLHPELAKIRTGLYEIKPGETVSGLLEKLNQGKEKVFAVTLVEGQSIKEWTAILNTLPHTETTEDVFNLVLSEQGDDSALPEGKFYPDTYHYRAGDNIKLLVTQSYNKMQQELEAAWAGRADNLPLKSPYELLIMASIIEKETGKASERPWISAVFINRLNKGMRLQTDPTVIYGMGESYKGDITRKALREMTPFNTYRINGLTPTPIAAPSGAALLAAAHPAEVNYLYFVSKNDGSHIFSRTLVEHNRAVNKYQRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQQ4</accession>
    <name>B1KQQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324639.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2009"/>
    <dbReference type="EnsemblBacteria" id="ACA86293">
        <property type="protein sequence ID" value="ACA86293"/>
        <property type="gene ID" value="Swoo_2009"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2009"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_4_0_6"/>
    <dbReference type="OrthoDB" id="1583074at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="307" mass="33448" checksum="BF6E4EF212F9F452" modified="2008-04-29" version="1">MKVVTIQTTWQDEPRHNVTKALELVESCCMSDSPDIICLPEFFLGPPWYMPGQSALQGITDTNIPGKITEQFGALSKKYAVYILLGSMVESLQNGKYCNTAVLLNRAGEIAGKAHKVHMFANETVVCEPGNSIEVINTEFGPIGIAVCSDFWVPETIRMLALKGAHTIFVPGGSLKQNLDAMVNAIHATAYLNCVNIVYISTVGEIHGERGGRTITVSFAGTSIIATPEGIIAKAPDNEASTLVAHLSIENILKLRAPTYNDDTWKNLLSRAPFSYKKLNEDYVGLGRDLVAETKKSIQQTQQIPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT6</accession>
    <name>B1KQT6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326027.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3424"/>
    <dbReference type="EnsemblBacteria" id="ACA87692">
        <property type="protein sequence ID" value="ACA87692"/>
        <property type="gene ID" value="Swoo_3424"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3424"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106753_0_0_6"/>
    <dbReference type="OMA" id="YPIAYNI"/>
    <dbReference type="OrthoDB" id="1596937at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="26347" checksum="A5A9B45FF6D44591" modified="2008-04-29" version="1">MQLKPLSKGRFHSLWQQEHHDIEEIMADCVSDTRLMPAHHKLMEQGQKVSTLILVKRGRISMGYTARNARSFQLGTMECDSQIFGEMEFFSDYLCQLDIIAEEELEVQIICGDKLQRALTQKPMFALFFASAIAIDYQDTVDILTRRMLYPIAYNIAYDLYHQYLNDQPVDGFTKCYLEAERFATTDRVYRRAVKRLEELGLILRDKEEGIVINDLDGLIAYIEER</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQY3</accession>
    <name>THII_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA sulfurtransferase</fullName>
            <ecNumber evidence="1">2.8.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sulfur carrier protein ThiS sulfurtransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Thiamine biosynthesis protein ThiI</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA 4-thiouridine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thiI</name>
        <name type="ordered locus">Swoo_3473</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + a uridine in tRNA + ATP + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = [ThiI sulfur-carrier protein]-L-cysteine + a 4-thiouridine in tRNA + AMP + diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24176"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:13337"/>
            <dbReference type="Rhea" id="RHEA-COMP:13338"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13340"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136798"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] = [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase]</text>
            <dbReference type="Rhea" id="RHEA:43340"/>
            <dbReference type="Rhea" id="RHEA-COMP:12157"/>
            <dbReference type="Rhea" id="RHEA-COMP:12158"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12910"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:90618"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThiI family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326073.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQY3"/>
    <dbReference type="SMR" id="B1KQY3"/>
    <dbReference type="STRING" id="392500.Swoo_3473"/>
    <dbReference type="EnsemblBacteria" id="ACA87739">
        <property type="protein sequence ID" value="ACA87739"/>
        <property type="gene ID" value="Swoo_3473"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3473"/>
    <dbReference type="eggNOG" id="COG0301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037952_4_1_6"/>
    <dbReference type="OMA" id="SMPEFCG"/>
    <dbReference type="OrthoDB" id="773697at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004810">
        <property type="term" value="F:tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140741">
        <property type="term" value="F:tRNA U4 sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052837">
        <property type="term" value="P:thiazole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01712">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00021">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026340">
        <property type="entry name" value="Thiazole_biosynth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020536">
        <property type="entry name" value="ThiI_AANH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003720">
        <property type="entry name" value="tRNA_STrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02568">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04271">
        <property type="entry name" value="ThiI_C_thiazole"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00342">
        <property type="entry name" value="TIGR00342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0676">Redox-active center</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000090035" description="tRNA sulfurtransferase">
        <location>
            <begin position="1"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="THUMP" evidence="1">
        <location>
            <begin position="63"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="406"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="1">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="1">
        <location>
            <begin position="346"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00021"/>
        </source>
    </evidence>
    <sequence length="484" mass="54651" checksum="8517D9115B9A1D50" modified="2008-04-29" version="1">MKFIVKLFPEIMMKSKPVRMRFTKMLETNIRNVLKKVDETAKVKREWDKIMVLVPDDRQDLVEAFAERLACIPGIAHVLQVSESTFESVDDIYQQTLAVYKDELAGKTFCVRVKRVGNHDFRSIEVERYVGGGLNQFTEAAGVRLKNPDMTINLEIDKESLYLVSKRIEGLGGYPMATQEDVLSLISGGFDSGVSSYQFIKRGSRTHYCFFNLGGDQHEIGVKQVAYHLWQKYGESHKVKFISIPFDPVVTEILEKIDNGQMGVILKRMMMRAAAKVARKMGIQALVTGEAMGQVSSQTLTNLSIIDRCTDQLILRPLIAMDKQDIINLSRKIGTEDLSKSIPEYCGVISQRPTVKAVLSKIEAEELKFSEDLIDRVIEAAEVIDIREIATSMDTKITSTETVGDINSGEVIIDVRAPEEEEQSPLEVEGVEVKAIPFFRLATKFADLDKSKTYLLYCDRGVMSKLQALYLQEQGYDNVKVYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR84</accession>
    <name>B1KR84_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type II and III secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323249.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0605"/>
    <dbReference type="EnsemblBacteria" id="ACA84901">
        <property type="protein sequence ID" value="ACA84901"/>
        <property type="gene ID" value="Swoo_0605"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0605"/>
    <dbReference type="eggNOG" id="COG4964">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017952_2_0_6"/>
    <dbReference type="OMA" id="LDYTATY"/>
    <dbReference type="OrthoDB" id="870677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032789">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13629">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767584" evidence="2">
        <location>
            <begin position="25"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="T2SS-T3SS_pil_N" evidence="3">
        <location>
            <begin position="29"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="49719" checksum="19CFF2540CB4F690" modified="2008-04-29" version="1" precursor="true">MKSRINFWAKGLIVSLFFCSYVMASDRFVTLNDASSIELKQEIGTVFISQPEVADYKITGNNKLVIYGRQLGQARLFVYNKANEVILSQLLHVDINLSQIRRQLKLFYPDLDLTLTSVGDKVAVRGIVYSEEQRNDIYRQVATFLGREKVERFDESELVEFKDSFTEANWLAYERNFIWQGIIEGLRLSQTQQVNVKISVAQVTKEFNETLGVSWSTVGRSVGEFSFLDFKASDLSTIINALGKDSIAEVLAEPNLSVMSGESASFLVGGEIPVIFSNNNTTNITYKEFGIRLDLSAKVLNNEKIKLQMMPEVSAVEGFVEAAGIKIPQLTTRRAMTTIELGDGDSFLLGGLMSSDELENVSKIPLLGDIPVFGALFRQAGTTRKKTELVIVATVNLVKPLSPTEVRLPKMTPTKSLARFFNITADSDENNKVNVIQMLNQGGFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR92</accession>
    <name>B1KR92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324645.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2015"/>
    <dbReference type="EnsemblBacteria" id="ACA86299">
        <property type="protein sequence ID" value="ACA86299"/>
        <property type="gene ID" value="Swoo_2015"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2015"/>
    <dbReference type="HOGENOM" id="CLU_1128452_0_0_6"/>
    <dbReference type="OrthoDB" id="2033974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="28006" checksum="2F36792E6132E1CC" modified="2008-04-29" version="1">MLNSTLGADNGDIPCKSQCPLDTNLYIGTIGQSVELPFLGGYIFEDAWLQIVNKMKLLKQTDVIGYLTEFCGNDALPKCDFSVINGINHIAFYLGDYDTNEQVLQWYSFLQNKAKCGEEITSVLMGPSYISPKQYGTQGWWYSLVFKDDFVIELFCCHRFGQWRDKSSKERVDLMSHLAFEVTQMEAVKPLIEGLERIENHLQVIAYTEQDEMGHTYGHVRNNQSNRVIELVHQLPIEDGGQGETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF5</accession>
    <name>B1KRF5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="7">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purC</name>
        <name evidence="9" type="ordered locus">Swoo_2078</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324707.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2078"/>
    <dbReference type="EnsemblBacteria" id="ACA86362">
        <property type="protein sequence ID" value="ACA86362"/>
        <property type="gene ID" value="Swoo_2078"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2078"/>
    <dbReference type="eggNOG" id="COG0152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064197_0_0_6"/>
    <dbReference type="OMA" id="QKARPVM"/>
    <dbReference type="OrthoDB" id="1345271at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014106">
        <property type="entry name" value="SAICAR_synthase_Vibrio-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02735">
        <property type="entry name" value="purC_vibrio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="8">
        <location>
            <begin position="47"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="368" mass="41440" checksum="42A5ECEE41D00ABE" modified="2008-04-29" version="1">MNLSNKVLAVNDDLPIRTDKAVHSGKVRSVYWLTEQDSARLIQQKGYDVPVDTPLAIMVISDRISAFDCIWQGEGGLNGVPGKGAALNAISNHWFKLFKEKGLADSHILDVPHPFVWIVQKAQPVMVEAIARQYITGSMWRAYSSGEREFCGIRLPEGLEKDQKLPEILITPSTKGVLTGLEGVPEADDVNVSRADLERHLEGFNFRNLSDIDLYEKLLKEGFAVISDALDAQDQIFIDTKFEFGYVKNANGQEKLIYMDEVGTPDSSRIWDGPAHRDGKIIEKSKEGFRQWLLNHFPDPDILLNKERMPERFALAADNKLPQSVMMDISNTYVGIAEKVIGKKLTISEDPKQEIIDILRNEYQLITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG1</accession>
    <name>B1KRG1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="13">2.7.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_2084</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2084"/>
    <dbReference type="EnsemblBacteria" id="ACA86368">
        <property type="protein sequence ID" value="ACA86368"/>
        <property type="gene ID" value="Swoo_2084"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2084"/>
    <dbReference type="eggNOG" id="COG1085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029960_0_0_6"/>
    <dbReference type="OMA" id="DWVMIAS"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00608">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019779">
        <property type="entry name" value="GalP_UDPtransf1_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="PTHR11943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000808">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00117">
        <property type="entry name" value="GAL_P_UDP_TRANSF_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 13" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="6 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GalP_UDP_transf" evidence="14">
        <location>
            <begin position="5"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="GalP_UDP_tr_C" evidence="15">
        <location>
            <begin position="184"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-UMP-histidine intermediate" evidence="10 12">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA86368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="357" mass="41056" checksum="B9D9A5E79B99FEAB" modified="2008-04-29" version="1">MTVEFDPTEHPHRRYNPLIDEWVLVSPHRAKRPWQGQVEALDEEDKLSYDENCFLCSGNTRINGEVNEKYTDTFVFKNDFAALKQDTPELHSDDPLFTMATERGESRVICFSPDHSKTLPQLSVAEITAVVKTWKAQTSALAESYQWVQVFENKGTVMGCSNPHPHGQIWAQDHLPTLVQKKQKAFDAYTHNYGTNLLQDYAKREISDELIQGERVVVSNADWMVVVPYWAAWPFETLLLPRFPVQRMTDLNGQQESSLADILQQITIRYDNLFNTSFPYSMGWHGAPFDGEEHPEWTLHASFFPPLLRSAQVRKFMVGYEMLAEAQRDLTPEQAAQRLRLASNEHYRTAGQFKAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG3</accession>
    <name>B1KRG3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SSS sodium solute transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2086</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324715.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2086"/>
    <dbReference type="EnsemblBacteria" id="ACA86370">
        <property type="protein sequence ID" value="ACA86370"/>
        <property type="gene ID" value="Swoo_2086"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2086"/>
    <dbReference type="eggNOG" id="COG4146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_9_3_6"/>
    <dbReference type="OMA" id="ACTNIAY"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="520" mass="56355" checksum="562B6299D4F85C50" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRL2</accession>
    <name>B1KRL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326110.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3513"/>
    <dbReference type="EnsemblBacteria" id="ACA87777">
        <property type="protein sequence ID" value="ACA87777"/>
        <property type="gene ID" value="Swoo_3513"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3513"/>
    <dbReference type="eggNOG" id="COG1145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_11_0_6"/>
    <dbReference type="OMA" id="DCCVPDD"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="85" mass="9461" checksum="61D4C41E821FF55D" modified="2008-04-29" version="1">MALLIDDSCINCDMCEPECPNQAITMGEEIYEIDPELCTECVGHYDKPTCISVCPIDCIDPDPDHNESDDELLVKYHLITGKPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRT0</accession>
    <name>B1KRT0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3581</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326178.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3581"/>
    <dbReference type="EnsemblBacteria" id="ACA87845">
        <property type="protein sequence ID" value="ACA87845"/>
        <property type="gene ID" value="Swoo_3581"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3581"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029002_5_0_6"/>
    <dbReference type="OMA" id="QWEVNLI"/>
    <dbReference type="OrthoDB" id="1530824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="7">
        <location>
            <begin position="57"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="266" mass="28693" checksum="42FD405B78072B51" modified="2008-04-29" version="1" precursor="true">MKLLPVLFLSTLALTGCVTTESPTGRNQILLFSSQEIDQMGASSFDQIKKQEKVSQDPKLNAYVDCVANRITSVLPKSNLPWDVVVFESDQVNAFALPGGHIGVYTGLLKVAANEDQLATVIGHEVAHVLANHSNEQVSRAKLTGTGMQLADVALGAGGVSNKDLYMAALGLGTQVGFILPYGREQESEADVMGVELMARAGFDPSQSMVLWQNMAKQGGEQGPELLSTHPSHGHRIDELTQMQSQVMPLYQASKGQVQNRCQKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD14</accession>
    <name>B1KD14_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">DNA polymerase I</fullName>
            <ecNumber evidence="3 13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">polA</name>
        <name evidence="17" type="ordered locus">Swoo_0060</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Single-chain monomer with multiple functions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3 13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0060"/>
    <dbReference type="EnsemblBacteria" id="ACA84361">
        <property type="protein sequence ID" value="ACA84361"/>
        <property type="gene ID" value="Swoo_0060"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0060"/>
    <dbReference type="eggNOG" id="COG0258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0749">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004675_0_0_6"/>
    <dbReference type="OMA" id="NRPPMPD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 13 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="15">
        <location>
            <begin position="33"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="14">
        <location>
            <begin position="346"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="16">
        <location>
            <begin position="702"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA84361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="945" mass="104564" checksum="14923CB2E72CE85F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ8</accession>
    <name>B1KDJ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0704"/>
    <dbReference type="EnsemblBacteria" id="ACA84999">
        <property type="protein sequence ID" value="ACA84999"/>
        <property type="gene ID" value="Swoo_0704"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0704"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_199070_0_0_6"/>
    <dbReference type="OMA" id="RHDPPWQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021948">
        <property type="entry name" value="DUF3565"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12088">
        <property type="entry name" value="DUF3565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="69" mass="7980" checksum="CD7BCBB128590D8C" modified="2008-04-29" version="1">MKQSIVSYLKDDENHWVAILQCGHYQHVRHTPPWVNRPWVITAQGRKSMLGYKLNCKKCDLGAAKDVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDN1</accession>
    <name>B1KDN1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutaredoxin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324773.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2144"/>
    <dbReference type="EnsemblBacteria" id="ACA86428">
        <property type="protein sequence ID" value="ACA86428"/>
        <property type="gene ID" value="Swoo_2144"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2144"/>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125054_4_2_6"/>
    <dbReference type="OMA" id="YHTEGCH"/>
    <dbReference type="OrthoDB" id="2001991at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="79" mass="9065" checksum="2BAA987E66380800" modified="2008-04-29" version="1">MADSRSNYILFHTDVCHLCELAAELLMQSAVKFESQDICDDETLVEQYGTRIPVLKQIDTNRELNWPFDIDALNEFLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE47</accession>
    <name>B1KE47_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323380.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0738"/>
    <dbReference type="EnsemblBacteria" id="ACA85033">
        <property type="protein sequence ID" value="ACA85033"/>
        <property type="gene ID" value="Swoo_0738"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0738"/>
    <dbReference type="eggNOG" id="ENOG5031UMS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_545004_0_0_6"/>
    <dbReference type="OMA" id="LFEMFKL"/>
    <dbReference type="OrthoDB" id="1356269at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764324" evidence="2">
        <location>
            <begin position="25"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="500" mass="56074" checksum="ACC9240C70896429" modified="2008-04-29" version="1" precursor="true">MKTSLSLPLLLSYLLLFIHLSAYANTQHTAQLNETQSAIESFQNDTQEILTQARKLNRQHGGHLERLNQMLAETKSAIAVLQSDLIKQLEQDATQMLQLTEAYLSYYRTFVYSISQDSSCYQPEQIDTFELTLIELQHYVDNIQTLASTPDEESAFAALMEINVEQTRVAMTVNLFEMFKLCYITEAVAPLSEQFNTLETQLTELAIQHGATPNNEIDDEFFVDDNLIQTELKHQSEIISTYEFMAGEMVNVNQLTYLHFDKLSQLSHLTLSNGLKIDQALNLQLPPNVAGNNEQLYSASITGRVETLDDIAQLNITIKRNPVLSIAKIQFSDKNIAACIEQSAQISQFTQAHQMELLSCELPRETSTKLNDLINFKQLTMISLKGGTIESLAPLAKLDSLETLYLSDIKLKEFGDLSSFSGSINLNQIDTQDWSKLAQTRANPLSINKPENCSELTPLFSHSNVAVLYKDMSSTEQVNAMEQVDSGAKTVMVITDCAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE63</accession>
    <name>B1KE63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323396.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0754"/>
    <dbReference type="EnsemblBacteria" id="ACA85049">
        <property type="protein sequence ID" value="ACA85049"/>
        <property type="gene ID" value="Swoo_0754"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0754"/>
    <dbReference type="eggNOG" id="COG4961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045933_0_0_6"/>
    <dbReference type="OMA" id="QARDYNF"/>
    <dbReference type="OrthoDB" id="403578at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="465" mass="52417" checksum="21B3B3BEB6A1F5E4" modified="2008-04-29" version="1" precursor="true">MLTRHKGQAMVLSLILMSFALMVVLFSFNASQLNLNGTKLQNTADNTAYSVATIAARDFNFKAYTNRASVANQVAVAQMVGLSSWFNMTDKFAENACNFLCWVPYLGQALSGIKSAVGAINTVAQPVFEALIYAENAMLYALTTSQQIIHYAGLLSSFNTAGKIVKANDPNARLDLLQNPQMLGDIKDHWIDFQKRHTRGSHRNKSKQFKDFITVTMNSRDPFAKKRSYKLGFPWSLSFFPIRWRTYKTGGSELISNNDRDSSKAETWTSMDTISFHLSKFRCSWSGCRWRGYRETPLGWGGTRSDNRADIRRIGNRNYWGSSRRTNGTAARYAGYDQETRGWYSGIQPFYGLSERGNNRSSGRNIAVVVSKPQNSVRTTSTVTAGEEHTNPATNEEMLGDRMTALSAAQVYYSRPHDLMARTSSWSRADGRHEYGNLYNPYWQTRLSDSTNTERSAVLAITRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE82</accession>
    <name>B1KE82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323415.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85068">
        <property type="protein sequence ID" value="ACA85068"/>
        <property type="gene ID" value="Swoo_0773"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0773"/>
    <dbReference type="eggNOG" id="ENOG5031KWH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107536_0_0_6"/>
    <dbReference type="OMA" id="FWISQVF"/>
    <dbReference type="OrthoDB" id="1519528at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="195" mass="22388" checksum="334054E757B979AA" modified="2008-04-29" version="1">MEIQSQPQASSEPVKRFPQLDNQELIKSSFWISQVFMIIATVTGVFLAAQEGLSQAITFDTLTNKQNNYYLRHALYDEVSDNVQLLNEYRENIVGKPTSTIKNFHPNMATFVWENMRYSQYTLETPSAILSETRRFYMQAEDIVNKIETRVYGAQYGGGLLKELTEKVSTQTLPALKANYTELANELKRNDIIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE93</accession>
    <name>B1KE93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323426.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0784"/>
    <dbReference type="EnsemblBacteria" id="ACA85079">
        <property type="protein sequence ID" value="ACA85079"/>
        <property type="gene ID" value="Swoo_0784"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0784"/>
    <dbReference type="eggNOG" id="ENOG502ZVP5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2107359_0_0_6"/>
    <dbReference type="OMA" id="DWINYAN"/>
    <dbReference type="OrthoDB" id="1860233at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="13201" checksum="F2ED11B6126AC26D" modified="2008-04-29" version="1">MAKKEKFILKADTFNRGALRMTVAILRDTNPKLALLVQNQMFAPLNPQVDNNPSPKDNFRVDLEPLDVRRVVEQLKIRELNPQTDPGTQMLIKALVIDWINYANFLIELENSKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA2</accession>
    <name>B1KEA2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [quinone]</fullName>
            <ecNumber evidence="5">1.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [menaquinone]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen IX dehydrogenase [ubiquinone]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protoporphyrinogen oxidase</fullName>
            <shortName evidence="5">PPO</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hemG</name>
        <name evidence="7" type="ordered locus">Swoo_0793</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a menaquinone + protoporphyrinogen IX = 3 a menaquinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:27409"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.5.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a quinone + protoporphyrinogen IX = 3 a quinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:65032"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3 a ubiquinone + protoporphyrinogen IX = 3 a ubiquinol + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:63936"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5">Binds 1 FMN non-covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HemG family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323435.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0793"/>
    <dbReference type="EnsemblBacteria" id="ACA85088">
        <property type="protein sequence ID" value="ACA85088"/>
        <property type="gene ID" value="Swoo_0793"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0793"/>
    <dbReference type="eggNOG" id="COG4635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094839_0_1_6"/>
    <dbReference type="OMA" id="ADTNIEY"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070819">
        <property type="term" value="F:menaquinone-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00853">
        <property type="entry name" value="HemG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044264">
        <property type="entry name" value="HemG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 5" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_5" evidence="6">
        <location>
            <begin position="5"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="173" mass="19687" checksum="590BCDB8A8CAA350" modified="2008-04-29" version="1">MSNILIIYSSVHGQTRKICAYLEDKFVALGDKVTMSSLDQVPDLNDFDKVVLGASIRHGKHNPNVYDFISQNRGILEKKTSSFFSVNLVARKPAKNTPQTNPYMLAFIEKSEWKPNLLQVFAGSLNYQGYGIVDRNIIRFIMWMTKGPTDAQTNIEYTDWAKVDLFSSEFHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KED5</accession>
    <name>B1KED5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
            <ecNumber evidence="1">3.1.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324857.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2232"/>
    <dbReference type="EnsemblBacteria" id="ACA86513">
        <property type="protein sequence ID" value="ACA86513"/>
        <property type="gene ID" value="Swoo_2232"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2232"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_1_6"/>
    <dbReference type="OMA" id="DHTLWDF"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011951">
        <property type="entry name" value="HAD-SF_hydro_IA_YjjG/PynA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02254">
        <property type="entry name" value="YjjG/YfnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="25150" checksum="8400ACCCC2B3E64B" modified="2008-04-29" version="1">MQYQWILFDADETLFHFDAFAGLKLMFSGFDIDFTLTDFEIYQRVNKPLWVDYQDGVISAAELQTKRFIEWGEKIGVTAQHLNSEFLKAMAEICDLLPGAKTLIEDLAGKASLGIITNGFTELQTVRLEKTGLLNAFHHVIISEEVGIAKPDVGIFDHALTRMNNPERSQVLMVGDNPHSDILGGLNAGLDTCWLNATEQERPDGITPHYEVKSLTELHRLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE8</accession>
    <name>B1KEE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2245</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324869.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2245"/>
    <dbReference type="EnsemblBacteria" id="ACA86526">
        <property type="protein sequence ID" value="ACA86526"/>
        <property type="gene ID" value="Swoo_2245"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2245"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_6"/>
    <dbReference type="OMA" id="HNVISDG"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="218" mass="24034" checksum="660858AAF980D8CC" modified="2008-04-29" version="1">MYKVLIADDHPLFRDAIVHIFGSKFPDSTTYETEDIASTLAFAKEHDDIDLILLDLNMPGMSGLNGLLDLSNECPTTPVVVVSAENKKQVILQTIAYGAVGFIAKSSSKETIAEAIETVFEGNIYLPADIIRTKSSPSSKKEYQLLPEMLSSLTRRQLMVLKCMTKGEANKQIAYNLNVSETTVKSHVSSILKKLGVSNRVQAVVGCSDIDFNQYLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF3</accession>
    <name>B1KEF3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PqqA binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Coenzyme PQQ synthesis protein D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pyrroloquinoline quinone biosynthesis protein D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pqqD</name>
        <name evidence="5" type="ordered locus">Swoo_2250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Monomer. Interacts with PqqE.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PqqD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324874.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2250"/>
    <dbReference type="EnsemblBacteria" id="ACA86531">
        <property type="protein sequence ID" value="ACA86531"/>
        <property type="gene ID" value="Swoo_2250"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2250"/>
    <dbReference type="eggNOG" id="ENOG5032Z81">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163864_2_1_6"/>
    <dbReference type="OMA" id="YVLLFPE"/>
    <dbReference type="OrthoDB" id="2008640at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00655">
        <property type="entry name" value="PQQ_syn_PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008792">
        <property type="entry name" value="PQQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022479">
        <property type="entry name" value="PqqD_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041881">
        <property type="entry name" value="PqqD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05402">
        <property type="entry name" value="PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03859">
        <property type="entry name" value="PQQ_PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="10129" checksum="68E2D1612CAB7E6B" modified="2008-04-29" version="1">MTLTVPKMNPLFRLQFEKAQGCFVLLYPEGMVKLNESAAEILQLVDGSASVDEIHKQLQHKFPQAGDIRHDIEEFLLVAQEKRWISYV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI0</accession>
    <name>ASTE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Succinylglutamate desuccinylase</fullName>
            <ecNumber evidence="1">3.5.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">astE</name>
        <name type="ordered locus">Swoo_2277</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transforms N(2)-succinylglutamate into succinate and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N-succinyl-L-glutamate = L-glutamate + succinate</text>
            <dbReference type="Rhea" id="RHEA:15169"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:58763"/>
            <dbReference type="EC" id="3.5.1.96"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.96" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324901.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KEI0"/>
    <dbReference type="SMR" id="B1KEI0"/>
    <dbReference type="STRING" id="392500.Swoo_2277"/>
    <dbReference type="EnsemblBacteria" id="ACA86558">
        <property type="protein sequence ID" value="ACA86558"/>
        <property type="gene ID" value="Swoo_2277"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2277"/>
    <dbReference type="eggNOG" id="COG2988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071608_0_0_6"/>
    <dbReference type="OMA" id="KRYLHSD"/>
    <dbReference type="OrthoDB" id="632656at2"/>
    <dbReference type="UniPathway" id="UPA00185">
        <property type="reaction ID" value="UER00283"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009017">
        <property type="term" value="F:succinylglutamate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:arginine catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019545">
        <property type="term" value="P:arginine catabolic process to succinate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03855">
        <property type="entry name" value="M14_ASTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00767">
        <property type="entry name" value="Arg_catab_AstE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016681">
        <property type="entry name" value="SuccinylGlu_desuccinylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017020">
        <property type="entry name" value="AstE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03242">
        <property type="entry name" value="arg_catab_astE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0056">Arginine metabolism</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000133647" description="Succinylglutamate desuccinylase">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00767"/>
        </source>
    </evidence>
    <sequence length="345" mass="38952" checksum="E49314346C98CE05" modified="2008-04-29" version="1">MLQALKESKDFLQLTLAQPQHFDETFTFMLGSHTQVEVWDTGVIVFEPKVARGKDIVLSCAVHGNETAPIELCNGLIKSLLEERLIAEQRVLFLFGNPPAIINGTRFIDENLNRLFNGAHSVGEGLVNPERIRAKKLEFYVDKFFSSSKDNSHKIHYDLHTAIRGSKHEKFAIYPYRPGRKYSGEQIMFLEACGIDTVLFHHEPTTTFSYFSSLNYQADAFTIELGKVLPMGQNDMTRFIALNEMLSRLIGNKSLELPDFNAKTVNLYQVCRAINKGFDDFEFTFANDVENFTSFPKGYILAKEGGENIKVEHEVEAIVFPNAKVPVGQRTVLCLKPASTENIDG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-03" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEL4</accession>
    <name>F16PA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fructose-1,6-bisphosphatase class 1</fullName>
            <shortName evidence="1">FBPase class 1</shortName>
            <ecNumber evidence="1">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fbp</name>
        <name type="ordered locus">Swoo_3770</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FBPase class 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326361.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KEL4"/>
    <dbReference type="SMR" id="B1KEL4"/>
    <dbReference type="STRING" id="392500.Swoo_3770"/>
    <dbReference type="EnsemblBacteria" id="ACA88029">
        <property type="protein sequence ID" value="ACA88029"/>
        <property type="gene ID" value="Swoo_3770"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3770"/>
    <dbReference type="eggNOG" id="COG0158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039977_0_0_6"/>
    <dbReference type="OMA" id="YIPENCP"/>
    <dbReference type="OrthoDB" id="945770at2"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="PTHR11556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000364715" description="Fructose-1,6-bisphosphatase class 1">
        <location>
            <begin position="1"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="106"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01855"/>
        </source>
    </evidence>
    <sequence length="329" mass="35865" checksum="5C4CBEFB58031A4F" modified="2008-04-29" version="1">MQTLAQNLTSQGVDASLTQLIHTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKLDVITNDMLKDALKADNTVRGLASEEEDYIVEVGDKGEYLVCFDPLDGSSNIDINSLVGTIFSVLPAPTGELTESSFLQAGRKQVAAGYVLYGPSTMLALTTGKGVQLFTLNPETNEYLLTTEAMSISKDTGEFAINMSNQRFWEAPMQTYISDLLLGTIGPREKAFNMRWIAAMVGDVHRVLSRGGIFTYPTDNKNPQKPYKLRLMYEANPMSFLVEQAGGIASTGYEAIMDIEPSEIHQRVAVILGSANEVKACLEYHSLDYSEEPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF23</accession>
    <name>B1KF23_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323521.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0880"/>
    <dbReference type="EnsemblBacteria" id="ACA85174">
        <property type="protein sequence ID" value="ACA85174"/>
        <property type="gene ID" value="Swoo_0880"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0880"/>
    <dbReference type="eggNOG" id="COG3137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058997_5_0_6"/>
    <dbReference type="OMA" id="NWENQYL"/>
    <dbReference type="OrthoDB" id="1623492at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007433">
        <property type="entry name" value="DUF481"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04338">
        <property type="entry name" value="DUF481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767005" evidence="1">
        <location>
            <begin position="21"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="27148" checksum="0C0E26CA1090A446" modified="2008-04-29" version="1" precursor="true">MKKLLIASAILMAAPFAAQAGADFVEGDKTFGGDAELGATITTGNTETTSLKGRLDMKHELGNWENQYLLEALYKEDTGEVTGKRYYGLFQADYKFDEVSYLFINANHEVDPFTGFDSKSTISSGYGHKFIDTGKTLFNVEVGPGYQYKRLDNESALEAGYDTEDSWVAHGVVNFETEITDSSTFKQMFVADYGESLEGRSETSITASIIGALAMKFAVVVRYNSEPLDNKESTDTETNMTLLYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFR4</accession>
    <name>B1KFR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Formate dehydrogenase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0937</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323577.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0937"/>
    <dbReference type="EnsemblBacteria" id="ACA85230">
        <property type="protein sequence ID" value="ACA85230"/>
        <property type="gene ID" value="Swoo_0937"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0937"/>
    <dbReference type="eggNOG" id="COG0493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_0_1_6"/>
    <dbReference type="OMA" id="SSPFITF"/>
    <dbReference type="OrthoDB" id="323168at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015942">
        <property type="term" value="P:formate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02790">
        <property type="entry name" value="MopB_CT_Formate-Dh_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02753">
        <property type="entry name" value="MopB_Formate-Dh-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041925">
        <property type="entry name" value="CT_Formate-Dh_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041924">
        <property type="entry name" value="Formate_Dh-H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006478">
        <property type="entry name" value="Formate_DH_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01591">
        <property type="entry name" value="Fdh-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00932">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="642"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="696"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="11">
        <location>
            <begin position="734"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="741"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="744"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="748"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="778"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1426" mass="156182" checksum="DDB2871DD8C84889" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS2</accession>
    <name>B1KFS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0945"/>
    <dbReference type="EnsemblBacteria" id="ACA85238">
        <property type="protein sequence ID" value="ACA85238"/>
        <property type="gene ID" value="Swoo_0945"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0945"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_590373_0_0_6"/>
    <dbReference type="OMA" id="RQPIYGL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="327"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="463" mass="52138" checksum="4D81B8561727979F" modified="2008-04-29" version="1">MPETNSIKCKFCCRVFDDYTFMSIYVAFIINVVLFSAFPLLLSTLQPVMRRIGFYSYLSVILVIGGVLGSLYSFQLADNIYLSGGNLAYGSFMMSAVMLFIMERKVLIFNYLIKLLVFINLFVFFGFNFILYILENALVINPFNVDAKLFDTSLGVLLLGGALIATEFLILMQIFIKVKDRISNLKQLMMLYSFVFILVICLDGVLFPLIAIGVSPELLPIMISNLSGKLILALSFSVPLFVFYCLYQNKLNRFVDTPMALSTVFFESRVRLTLELDKLERAAKQLIDDNQKLINLSHYDHLTGLANRRKYDDYASALYTRAVELGEPVTLVLGDIDHFKKYNDFYGHQSGDECLQRVAEFWKEILLEEERLTARIGGEEFAVIIANRTAEAILPQLKRDIAGLTALAIPHAASSTASIVTMSIGVASMLPSREGDFELLFETADKALYQAKNSGRNQISTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFZ7</accession>
    <name>B1KFZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325046.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2426"/>
    <dbReference type="EnsemblBacteria" id="ACA86704">
        <property type="protein sequence ID" value="ACA86704"/>
        <property type="gene ID" value="Swoo_2426"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2426"/>
    <dbReference type="eggNOG" id="ENOG5033DQT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139764_0_0_6"/>
    <dbReference type="OMA" id="FMGIIPV"/>
    <dbReference type="OrthoDB" id="2075261at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17330" checksum="EA139E3C4BAB4479" modified="2008-04-29" version="1">MLPVKFLSQLRLYFPLLIILSLMGCSKEKSPETSGFVQDDTLCQFHLGYCDKNVADINLQLLITPFDTPSEKPLNISIISSKEIDDLKVKIEGRDMFMGVIPVNMNKAGENIYKGELIYGSCSSDYMVWRAFVSFTLKGEAKVAIFDFLADNQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG57</accession>
    <name>B1KG57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NnrUfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325106.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2487"/>
    <dbReference type="EnsemblBacteria" id="ACA86764">
        <property type="protein sequence ID" value="ACA86764"/>
        <property type="gene ID" value="Swoo_2487"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2487"/>
    <dbReference type="eggNOG" id="COG4094">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104582_1_0_6"/>
    <dbReference type="OMA" id="VKIWALA"/>
    <dbReference type="OrthoDB" id="1734625at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009915">
        <property type="entry name" value="NnrU_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07298">
        <property type="entry name" value="NnrU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="NnrU" evidence="2">
        <location>
            <begin position="3"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="20889" checksum="89D3E780CD70705D" modified="2008-04-29" version="1" precursor="true">MWMLLVGLLLWSLVHFIPSATPSLKQSWIAKTSDKGYMLSFSILIISSLCLIVFGWRAAPIEFVYTLPQSTKPIAVVLMLIASMLFAAAKQKTNIKRVIRHPQLTSVLVWSIAHLILNGDSRSLILFGGMCLWSLWQIYFINKREGAWSKPEPVSWRNEIKVLLVGGVIFVILALIHPYLSGVAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG62</accession>
    <name>B1KG62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2492"/>
    <dbReference type="EnsemblBacteria" id="ACA86769">
        <property type="protein sequence ID" value="ACA86769"/>
        <property type="gene ID" value="Swoo_2492"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2492"/>
    <dbReference type="HOGENOM" id="CLU_1947353_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14693" checksum="82CEC7ED8969F05E" modified="2008-04-29" version="1">MILKFYCHVSLISNLYSIQKITKEVKMINLILLTSALLQLPSNTLVSNDVTKTTLETVHTKAFIETWEPQEHSVSLDNIEQRLSMEIMANLDGEFELVLAKIDDELTSQVELSIETHSTMEKLTQQNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG72</accession>
    <name>B1KG72_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH-ubiquinone oxidoreductase chain 4L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3952</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326539.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3952"/>
    <dbReference type="EnsemblBacteria" id="ACA88209">
        <property type="protein sequence ID" value="ACA88209"/>
        <property type="gene ID" value="Swoo_3952"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3952"/>
    <dbReference type="eggNOG" id="COG1006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082058_2_0_6"/>
    <dbReference type="OMA" id="KRHGTVD"/>
    <dbReference type="OrthoDB" id="2078994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="13250" checksum="D7EA21EE075053F4" modified="2008-04-29" version="1">MFLGLYNYWIVVLLMMIGFYIVIAHGNLIKKLVGLTIFQTSVFIFYISVGMVERGSAPILAEGISDYSNPLPHVLILTAIVVGIATTALGLALAVRIKESYGSVEEDEIQRQDQLNEDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGD7</accession>
    <name>B1KGD7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326603.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4018"/>
    <dbReference type="EnsemblBacteria" id="ACA88274">
        <property type="protein sequence ID" value="ACA88274"/>
        <property type="gene ID" value="Swoo_4018"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4018"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_29_4_6"/>
    <dbReference type="OMA" id="ERGEQNM"/>
    <dbReference type="OrthoDB" id="2063007at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="68" mass="7743" checksum="BB11FA1448BA6FFD" modified="2008-04-29" version="1">MKDLAIQFGLKLREKRKELGISQDKLALLAEIDRSYAGRIERGEVNITLEKAYQLAEVLGCEVRELLP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG6</accession>
    <name>ARGR_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arginine repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argR</name>
        <name type="ordered locus">Swoo_1001</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Regulates arginine biosynthesis genes.</text>
    </comment>
    <comment type="pathway">
        <text>Amino-acid biosynthesis; L-arginine biosynthesis [regulation].</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArgR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323641.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KGG6"/>
    <dbReference type="SMR" id="B1KGG6"/>
    <dbReference type="STRING" id="392500.Swoo_1001"/>
    <dbReference type="EnsemblBacteria" id="ACA85294">
        <property type="protein sequence ID" value="ACA85294"/>
        <property type="gene ID" value="Swoo_1001"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1001"/>
    <dbReference type="eggNOG" id="COG1438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097103_2_0_6"/>
    <dbReference type="OMA" id="MVYCLPP"/>
    <dbReference type="OrthoDB" id="1640037at2"/>
    <dbReference type="UniPathway" id="UPA00068"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034618">
        <property type="term" value="F:arginine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00173">
        <property type="entry name" value="Arg_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001669">
        <property type="entry name" value="Arg_repress"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020899">
        <property type="entry name" value="Arg_repress_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036251">
        <property type="entry name" value="Arg_repress_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020900">
        <property type="entry name" value="Arg_repress_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34471">
        <property type="entry name" value="PTHR34471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01316">
        <property type="entry name" value="Arg_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02863">
        <property type="entry name" value="Arg_repressor_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01467">
        <property type="entry name" value="ARGREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55252">
        <property type="entry name" value="SSF55252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01529">
        <property type="entry name" value="argR_whole"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0055">Arginine biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000097888" description="Arginine repressor">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00173"/>
        </source>
    </evidence>
    <sequence length="156" mass="16991" checksum="218950DC8CAB4573" modified="2008-04-29" version="1">MQAAKTQDELVKTFKAILKEERFGSQSEIVIALQAEGYNNINQSKVSRMLSKFGAVRTRNAKQEMVYCLPAELGVPTAGSPLKNLVLDVDHNQAMIVVRTSPGAAQLIARLLDSIGKPEGILGTIAGDDTIFITPSNIQEIDKTLITVKSLFNFTN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGH1</accession>
    <name>OBG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GTPase Obg</fullName>
            <ecNumber evidence="1">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">obg</name>
        <name type="ordered locus">Swoo_1006</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323646.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KGH1"/>
    <dbReference type="SMR" id="B1KGH1"/>
    <dbReference type="STRING" id="392500.Swoo_1006"/>
    <dbReference type="EnsemblBacteria" id="ACA85299">
        <property type="protein sequence ID" value="ACA85299"/>
        <property type="gene ID" value="Swoo_1006"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1006"/>
    <dbReference type="eggNOG" id="COG0536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011747_2_0_6"/>
    <dbReference type="OMA" id="VVFDWEP"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000386253" description="GTPase Obg">
        <location>
            <begin position="1"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Obg" evidence="2">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="1">
        <location>
            <begin position="160"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="213"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="283"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="314"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="389" mass="43079" checksum="4129A033982A0FE9" modified="2008-04-29" version="1">MKFVDEAVIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADESYNTLIDFQFERFHRAERGKNGRGRDCTGHGGEDLILTVPVGTRAIDEETQESLGDLTKHGQRMLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLKLELMLLADVGLLGMPNAGKSTFIRSVSRAKPKVADYPFTTLVPNLGVVNPRHGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRVLLHILDIDPIDGSDPVESARAIVAELEKHSPKLASKPRWLVINKTDLMLEDELKERVENIVKELEWEGDVYTISAYNREGTEALSLKLIDFIEALPPEEEIDKEAEVEFKWDNYHENANESLNENFEDDFDDDDDFDDDDYDVKVIYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGJ3</accession>
    <name>B1KGJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323668.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85321">
        <property type="protein sequence ID" value="ACA85321"/>
        <property type="gene ID" value="Swoo_1028"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1028"/>
    <dbReference type="eggNOG" id="COG3313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162538_0_0_6"/>
    <dbReference type="OMA" id="WLEFSDA"/>
    <dbReference type="OrthoDB" id="2068388at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010710">
        <property type="entry name" value="DUF1289"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35175">
        <property type="entry name" value="PTHR35175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06945">
        <property type="entry name" value="DUF1289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="103" mass="12181" checksum="26187052C507F747" modified="2008-04-29" version="1">MEQLEFFEIQSPCIGVCQTDARGYCKGCLRNRDERFNWLEFSDAKKYDVIRLCKQRKRRRQLAILKARKAQLLQERADLNPSFDFEASDPEEPSLSNDDFTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGP8</accession>
    <name>B1KGP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323722.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1083"/>
    <dbReference type="EnsemblBacteria" id="ACA85376">
        <property type="protein sequence ID" value="ACA85376"/>
        <property type="gene ID" value="Swoo_1083"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1083"/>
    <dbReference type="eggNOG" id="COG1585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100961_0_0_6"/>
    <dbReference type="OMA" id="GNWHVLR"/>
    <dbReference type="OrthoDB" id="1220641at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010840">
        <property type="entry name" value="YqiJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07290">
        <property type="entry name" value="DUF1449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="211" mass="22580" checksum="9D2288FCB100787E" modified="2008-04-29" version="1">MVEFLFAQANLPFSISLSFVLLLGIFEALSLVLGYSLVGAMDDWAPIDLDVDADGSASGFTGVSGWLCLNRLPLLIWFVLVLVSFSITGYTSNFLSLLLTDQPLPQIISLPIALILTAFSCRYVGAAVAKVLPKNESTAVSIDTLLGSIGTVTLGCAIKGNPSEALVKDQHQQKHYVLVEPEVAGVEFQTGTQVVLLKREGTVWSAAKFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV4</accession>
    <name>B1KGV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SEC-C motif domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2546"/>
    <dbReference type="EnsemblBacteria" id="ACA86823">
        <property type="protein sequence ID" value="ACA86823"/>
        <property type="gene ID" value="Swoo_2546"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2546"/>
    <dbReference type="eggNOG" id="COG3012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099590_0_0_6"/>
    <dbReference type="OMA" id="WLYVDGD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="18537" checksum="52CA8F29DF66627F" modified="2008-04-29" version="1">MTTETETLCPCGQNDREHPHLYTDCCAPYHQNIKTAGTPEKLMRSRYAAFVLGEYDYLIQTHHRDYLGDLTVEVLAEHTPQWLSLQVLSTQTKGDMGEVCFQAWYRDGNNIDAIHECSQFVQEANRWFYTQGTQKPAIYPKRNDTCLCNSGRKYKQCCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGW7</accession>
    <name>B1KGW7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ion-translocating oxidoreductase complex subunit D</fullName>
            <ecNumber evidence="10">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Rnf electron transport complex subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rnfD</name>
        <name evidence="11" type="ordered locus">Swoo_2559</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NqrB/RnfD family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325177.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2559"/>
    <dbReference type="EnsemblBacteria" id="ACA86836">
        <property type="protein sequence ID" value="ACA86836"/>
        <property type="gene ID" value="Swoo_2559"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2559"/>
    <dbReference type="eggNOG" id="COG4658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042020_0_0_6"/>
    <dbReference type="OMA" id="GWQWINL"/>
    <dbReference type="OrthoDB" id="1654433at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00462">
        <property type="entry name" value="RsxD_RnfD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011303">
        <property type="entry name" value="RnfD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578">
        <property type="entry name" value="PTHR30578"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578:SF0">
        <property type="entry name" value="PTHR30578:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01946">
        <property type="entry name" value="rnfD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="10">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="350" mass="37924" checksum="01E7DA67C8112078" modified="2008-04-29" version="1">MAFKIASSPHLSRNFQTSTLMQRVILCTLPGVATQCYFFGWGVLIQVALAITVALISEAIVLQLRKRPVTDTLKDNSALLTALLLGIAIPPLAPWWLTVMGVLFAIVIVKHLYGGLGHNIFNPAMAGYVMLLISFPVQMTSWVAPMMLASQPVDLLGSLQLIFLNPSASEIEAYKLGFDGVAMATPLDTIKTDLSMGLTSIESLTKSIFNDGFGVGWFWVNMAYLAGGLAMIKLNLIRWHIPVGVLASLFICASVGYLLNPDTHVGPLLHLFSGATMLAAFFIATDPVTAATSVRGRLLFGALIGVLVYVIRTYGGYPDAFAFAILLANLCAPFIDHYIKPRTYGHRSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGZ6</accession>
    <name>B1KGZ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AIG2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326637.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4052"/>
    <dbReference type="EnsemblBacteria" id="ACA88308">
        <property type="protein sequence ID" value="ACA88308"/>
        <property type="gene ID" value="Swoo_4052"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4052"/>
    <dbReference type="eggNOG" id="COG2105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048475_6_0_6"/>
    <dbReference type="OMA" id="YIANTHD"/>
    <dbReference type="OrthoDB" id="1984556at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="PTHR12935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="SSF110857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="18079" checksum="199554EACF14F013" modified="2008-04-29" version="1">MKYFAYGSNMSIARLKARTPSAKRIGTFILTGHELRFHKLGRDGSGKCDAYQTGEPQSQVFGALFEIDELEKPSLDLAESLGVGYGEKVVKVVSAAGEEHEAITYYALNILPSLKPYSWYLNHVIIGAIESQLPTSYLELIQTTESIEDEDLLRDKLERGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH64</accession>
    <name>B1KH64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326705.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4120"/>
    <dbReference type="EnsemblBacteria" id="ACA88376">
        <property type="protein sequence ID" value="ACA88376"/>
        <property type="gene ID" value="Swoo_4120"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4120"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124904_1_0_6"/>
    <dbReference type="OMA" id="RVNAYWS"/>
    <dbReference type="OrthoDB" id="1775689at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="141" mass="15766" checksum="B264CE431ADA5957" modified="2008-04-29" version="1" precursor="true">MKLLMVLLTLICLLPTVVAEELLVVVSEGSRVESLTKGEVVDLFMGRYVTFPNGDKARVFDLASKSKTKGQFYKLLVNRTEAQVNAYWARLLFSGRSVPPEEADSPEALITQIQQTDLAIGYISSQDLTEGLKVVYRFETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHA9</accession>
    <name>B1KHA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323763.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1124"/>
    <dbReference type="EnsemblBacteria" id="ACA85417">
        <property type="protein sequence ID" value="ACA85417"/>
        <property type="gene ID" value="Swoo_1124"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1124"/>
    <dbReference type="eggNOG" id="ENOG5031HY8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_949617_0_0_6"/>
    <dbReference type="OMA" id="VWFGANG"/>
    <dbReference type="OrthoDB" id="1325772at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767352" evidence="1">
        <location>
            <begin position="19"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="294" mass="33547" checksum="D3A91454E45A6F3E" modified="2008-04-29" version="1" precursor="true">MKKLLLCTLCAISPFAYSSSNDVLYLHYDEVLDGATDYQKQLKLNIDLSGNTVIGKTAAGELISGRVENTDSQYIGSGDKPRFQFEIHQGETRNWYFGQVDGKYWEGVWFGANGEKGDFSLYTDLLTKEVPQFENIIAYYADEVFNFGGNNSHNSLNSSFLVDSDSLEPHFTNLEHFDTSQGLFLQADVLHGNLPMSFYMDFEKPMGMKTFRLGSYNNGEGTRLRTFTFDIWKHGEWETVGSFEFAPIYAPSYQRQEFNLPRMVYADRIRISATATDDYTNGSKVLMWGLSFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHD1</accession>
    <name>B1KHD1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sugar (Glycoside-Pentoside-Hexuronide) transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1146</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:galactoside symporter (TC 2.A.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323785.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1146"/>
    <dbReference type="EnsemblBacteria" id="ACA85439">
        <property type="protein sequence ID" value="ACA85439"/>
        <property type="gene ID" value="Swoo_1146"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1146"/>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027408_0_2_6"/>
    <dbReference type="OMA" id="LPMAEWF"/>
    <dbReference type="OrthoDB" id="1249292at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001927">
        <property type="entry name" value="Na/Gal_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018043">
        <property type="entry name" value="Na/Gal_symport_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="PTHR11328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00792">
        <property type="entry name" value="gph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00872">
        <property type="entry name" value="NA_GALACTOSIDE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="442" mass="49112" checksum="02B3A939BD2D2B5D" modified="2008-04-29" version="1">MVSVKEKIAYGLGDTASNIVFQTVMLFLTFFYTDIFGIPPAFVGTMFLAVRLIDAITDPLMGAMTDRTQTRYGKFRPYLLWFALPFGLFSVLAFTTPDLSEQGKMIYAFVTYTALMMVYTAINIPYCALGGVLTSDPKERVSVQSYRFVFAMLGGLLVSGLTLPLVEFLGEGDQAKGYQLTITAMSILGVAMFLICFWNTKERLTPSQPHQSSFKQDVGYLVKNDQWRILCIASVCLLSGMVLKTSLAIYYVKYFLQMPDKITLFITLGMVGNIFGCMLAQPLAKRVCKVNAYISLQLIAAALCIATYFVPKEQVELAFAMFILWGFAFNMATPLLWAKMADTVDYGQYKDGVRLTGIIYSSIIFFIKLGVAIGGAAAGWLLSGYGYQADVEQTPQTLNGILLSFTVYPAVGSILVAIVMRKYTLKNSKVDEIHLELNRMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR6</accession>
    <name>B1KHR6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326723.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4138"/>
    <dbReference type="EnsemblBacteria" id="ACA88394">
        <property type="protein sequence ID" value="ACA88394"/>
        <property type="gene ID" value="Swoo_4138"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4138"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049016_0_0_6"/>
    <dbReference type="OMA" id="EYHWVEG"/>
    <dbReference type="OrthoDB" id="958173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764497" evidence="1">
        <location>
            <begin position="23"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="390" mass="44846" checksum="6C90E48A93EDA0C2" modified="2008-04-29" version="1" precursor="true">MSILVRFFASLILLSTWSIASASELQFNGFIGQGAMVADDTQFIVGSDDHAFDITEAAFGVSWKPMEHFRVASALSFRQWGELYDSKVKFDYLFAEYTYHFGDETLGVRGGLFKNEAGFYSSTRDVPFTRPSIMLPQSIYSDYFRDAQLHIEGGDLFGVHQIFDGTLDWHLAFGKVDVTEDLERNVMGGTELGEFDSEHYYAADIEFQNNYMRLGVTYYDAEVSYAAPMSGNYFPGDIQLINWVFSGQFRYQNFELTGEYLTGDRIINGLVFPEQFGELKEPSLGYYLDFRTYLPHEVELFIRFDKHIDNADDKDGQDYENSTGIPAYFAYSNDWTIGARWFPSHDWLLAVEYHQVEGASWVTPVVYPNPSVQAKNWSMFALQVSYRFQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV6</accession>
    <name>B1KHV6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oligoribonuclease</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">orn</name>
        <name evidence="5" type="ordered locus">Swoo_4178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">3'-to-5' exoribonuclease specific for small oligoribonucleotides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the oligoribonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326763.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4178"/>
    <dbReference type="EnsemblBacteria" id="ACA88434">
        <property type="protein sequence ID" value="ACA88434"/>
        <property type="gene ID" value="Swoo_4178"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4178"/>
    <dbReference type="eggNOG" id="COG1949">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064761_2_0_6"/>
    <dbReference type="OMA" id="AFFHYRN"/>
    <dbReference type="OrthoDB" id="1390327at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00045">
        <property type="entry name" value="Oligoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="4">
        <location>
            <begin position="7"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="20703" checksum="C64EE76C94D5DCA7" modified="2008-04-29" version="1">MAADANNLIWVDLEMTGLEPDVDRIIEIATIVTDKELNIIAEGPVIAIHQSDEQLAKMDDWNKKHHGESGLVDRVRSSQYSEAQAVAMTIEFLSQHVTKGSSPMCGNSVGQDRRFMTLYMRELEDFFHYRNIDVSTVKELVRRWDPEVMNGFSKLGTHKALIDIQESIAELQYYRAKVFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY0</accession>
    <name>B1KHY0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326787.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4202"/>
    <dbReference type="EnsemblBacteria" id="ACA88458">
        <property type="protein sequence ID" value="ACA88458"/>
        <property type="gene ID" value="Swoo_4202"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4202"/>
    <dbReference type="eggNOG" id="ENOG5031EB5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181573_0_0_6"/>
    <dbReference type="OMA" id="AQMQDMM"/>
    <dbReference type="OrthoDB" id="2029612at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764895" evidence="2">
        <location>
            <begin position="29"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="10582" checksum="FDB277A9D70F3E5A" modified="2008-04-29" version="1" precursor="true">MFNSTISKIAKSSLVVAVLMGASATANADTLIPTDLTSNLEQNIAAQMQDMMQVAQRELSISLQAQLSSSMFDAEESDEAEQLAQEPTELAITSAMVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY2</accession>
    <name>B1KHY2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CheC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4204</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4204"/>
    <dbReference type="EnsemblBacteria" id="ACA88460">
        <property type="protein sequence ID" value="ACA88460"/>
        <property type="gene ID" value="Swoo_4204"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4204"/>
    <dbReference type="eggNOG" id="COG1406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116290_0_0_6"/>
    <dbReference type="OMA" id="MGEIANM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038756">
        <property type="entry name" value="CheX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028051">
        <property type="entry name" value="CheX-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39452">
        <property type="entry name" value="PTHR39452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13690">
        <property type="entry name" value="CheX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheX" evidence="3">
        <location>
            <begin position="42"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="204" mass="21749" checksum="887C3E2C313196EC" modified="2008-04-29" version="1">MNVNFINPFLESLINVISTMANMQLTPGKPGLKQGNLAKGDVSGLIGMVGPQTKGSLSITFELNLVLEIMQNMLGENPGMMNEEITDLVGEITNMVTGGAKNKLGDKGYEFDMATPIVVSGIGHTISHKANGKKIIMPFTSPHGAAYIEICFEDVNKTPEATSTDAEPNEAENDEAKSESDNKAATNEDTNSKDNTDEEAAPKS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY7</accession>
    <name>RL9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplI</name>
        <name type="ordered locus">Swoo_4209</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326794.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHY7"/>
    <dbReference type="SMR" id="B1KHY7"/>
    <dbReference type="STRING" id="392500.Swoo_4209"/>
    <dbReference type="EnsemblBacteria" id="ACA88465">
        <property type="protein sequence ID" value="ACA88465"/>
        <property type="gene ID" value="Swoo_4209"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4209"/>
    <dbReference type="eggNOG" id="COG0359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078938_4_1_6"/>
    <dbReference type="OMA" id="MKIILTH"/>
    <dbReference type="OrthoDB" id="1959318at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000126972" description="50S ribosomal protein L9">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <sequence length="150" mass="15708" checksum="7A1FD7BAB8C034ED" modified="2008-04-29" version="1">MNVILLDKIANLGNLGDQVAVKAGYARNFLLPQGKAVVANAANTEVFEARRAELEAKLAADLAVATERADKINALESVVIASKAGDEGKLFGSIGNRDIADAVTAAGVELAKSEVRLPLGALRTTGEFEVEVQVHTEVKAIVKLSVVAED</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI57</accession>
    <name>RNC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease 3</fullName>
            <ecNumber evidence="1">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ribonuclease III</fullName>
            <shortName evidence="1">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rnc</name>
        <name type="ordered locus">Swoo_1243</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323881.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI57"/>
    <dbReference type="SMR" id="B1KI57"/>
    <dbReference type="STRING" id="392500.Swoo_1243"/>
    <dbReference type="EnsemblBacteria" id="ACA85535">
        <property type="protein sequence ID" value="ACA85535"/>
        <property type="gene ID" value="Swoo_1243"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1243"/>
    <dbReference type="eggNOG" id="COG0571">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000907_1_1_6"/>
    <dbReference type="OMA" id="LTHKSCK"/>
    <dbReference type="OrthoDB" id="1890943at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000094132" description="Ribonuclease 3">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="7"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="1">
        <location>
            <begin position="155"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <sequence length="225" mass="25213" checksum="81A90C7030170A77" modified="2008-04-29" version="1">MEPIKNIPRLCRTLGYDFSELALLDHALTHRSAASKHNERLEFLGDSILSIIISDALYHQFPKATEGDLSRMRATLVCGKMLAEIGFEFKLGDYLKLGPGELKSGGFRRESIIADAVEAIIGAVYLDSDLEVTRSLVLGWYKTRLETIQPINQKDPKTLLQELLQGYKKPLPVYKVTDIRGEAHAQTFTIECYVEELRKPVVGVASSRRKAEQLAAAQALELIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI76</accession>
    <name>B1KI76_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323900.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85554">
        <property type="protein sequence ID" value="ACA85554"/>
        <property type="gene ID" value="Swoo_1262"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1262"/>
    <dbReference type="eggNOG" id="COG3671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129294_1_0_6"/>
    <dbReference type="OMA" id="RWQRWSI"/>
    <dbReference type="OrthoDB" id="2027657at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12180" checksum="A0E00D3174BADAE6" modified="2008-04-29" version="1">MISTATEGAAIDDPSLAHLLYGLMTAFPLFFLPTLLGLAINLAHKPQGASAMVQSHLRWQRHSMIGFAILAGLGFFLSPLWLSVSIYLVATLWFCHRIIKGWLSLTEGVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI92</accession>
    <name>B1KI92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative transmembrane lysine/arginine export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2667</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2667"/>
    <dbReference type="EnsemblBacteria" id="ACA86943">
        <property type="protein sequence ID" value="ACA86943"/>
        <property type="gene ID" value="Swoo_2667"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2667"/>
    <dbReference type="eggNOG" id="COG1279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2737815_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="71" mass="7826" checksum="68CFADABE3419478" modified="2008-04-29" version="1">MVLLGSISTQYEGTKEWFTLGAVSGSFVFFFSLGYGARILIPIFKKPVSWKVLEFVIAFIMFAIAASLLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI94</accession>
    <name>B1KI94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325285.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2669"/>
    <dbReference type="EnsemblBacteria" id="ACA86945">
        <property type="protein sequence ID" value="ACA86945"/>
        <property type="gene ID" value="Swoo_2669"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2669"/>
    <dbReference type="eggNOG" id="ENOG502ZREC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113667_0_0_6"/>
    <dbReference type="OMA" id="KHGWFWR"/>
    <dbReference type="OrthoDB" id="1798507at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="23080" checksum="BFEA07E7F3CEAEC0" modified="2008-04-29" version="1">MTNQKNSNEISVEIPVHSTATLVKASIAASMIAAVVLLIAILPAEYNIDPTGLGKSLGLTQLSQNGLLESEKVSGSSDPKATLPVSETGFQAVADAPSLEQIAQRRQTPGVRSDLVNIDIPAGKGLEYKLLMDAHTHLEYEWSTDGEPLYFDFHGEPKGDKTGYFESFSITTSDKMKGSLTTPFAGSHGWYWKNQTDSVITVTLSTKGDYQIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ2</accession>
    <name>B1KIQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326875.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88548">
        <property type="protein sequence ID" value="ACA88548"/>
        <property type="gene ID" value="Swoo_4293"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4293"/>
    <dbReference type="HOGENOM" id="CLU_1160452_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="28149" checksum="7E626D3AD139ED5C" modified="2008-04-29" version="1">MYKKNLEFKPVKTWEYLGGRNGESLLLLWGKSAIGPFLFVILFSLMMFDTPSVYELPPIIFSFVILVVSLRYTALGSVKRSYYLYEDRVRCEEADYRRLSLRYLLWFSFVLLLIVSVFTVYYDDIRSLIICLFFCCMLYREILLCNYWKSDFGLVFGERQELYVLKAKRIVYLVVGNDIGYESFLDRCRYDISFHIKMNKIKLCFKTNDDLNDFISELSGVAPDSSVFYDISSTSLILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIR1</accession>
    <name>B1KIR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326884.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4303"/>
    <dbReference type="EnsemblBacteria" id="ACA88557">
        <property type="protein sequence ID" value="ACA88557"/>
        <property type="gene ID" value="Swoo_4303"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4303"/>
    <dbReference type="eggNOG" id="ENOG5032ZFG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139617_1_0_6"/>
    <dbReference type="OMA" id="SPSMDMY"/>
    <dbReference type="OrthoDB" id="1723691at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="104" mass="11805" checksum="3BDDEC4EF4CB80AD" modified="2008-04-29" version="1">MKFNHLGIPTIERFDGEIDLPHLKMTVSDHQNNPYGIQWQRFWADAPYPELVKTVPHAAFEVDDLMAEIKGKKVIIEPNSPSEGLIVAFIEVNGAPVELMEYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIW0</accession>
    <name>B1KIW0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323954.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1316"/>
    <dbReference type="EnsemblBacteria" id="ACA85608">
        <property type="protein sequence ID" value="ACA85608"/>
        <property type="gene ID" value="Swoo_1316"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1316"/>
    <dbReference type="eggNOG" id="COG3038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095321_4_1_6"/>
    <dbReference type="OMA" id="WYKTAPH"/>
    <dbReference type="OrthoDB" id="1940783at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="9"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20781" checksum="00A9EBE2CB2903D4" modified="2008-04-29" version="1" precursor="true">MFRNTEASYGLASILFHWVSALAVISLFVLGYWMVDLTYYSTWYKTAPYLHKSFGLLLLLLTLIRLVWKVVNPKPKADPNHKRWEQKAGHIAHLAIYLLLIVIMFSGYLISTADARGIWVFDWFEVPGFGSFIDGQADVAGLIHQYAAYSLMGLTLIHALGAIKHHVIDKDSTLLRMIKVIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIW8</accession>
    <name>B1KIW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323962.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1324"/>
    <dbReference type="EnsemblBacteria" id="ACA85616">
        <property type="protein sequence ID" value="ACA85616"/>
        <property type="gene ID" value="Swoo_1324"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1324"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="WHEHSVW"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="313" mass="34671" checksum="391B149CD00F5B37" modified="2008-04-29" version="1">MLELLEPIAIFTHVARAGSFSAAARKLGISKSKVSTQVADLEHKLGVQLIQRTTRSLSLTEAGQLLYTQGEELLRDADQAVASVHNLNDATRGVLKVGISQSFGTMHIIPALPEFMTTHPELELQVSLLDHKVDVVSEGLDLLLTMSEQLPLGMVARPLMKCQFLLVASPDYIEKHGQPDRPEQLVDHNCLVYQGEWHEHSVWQFKQGDDYCEIGVSGNFRVDNAPALKSAAVSGLGVVYLASYLLEDEIAKGTLVPLLEDWQLTHHLPLQAVYPRRKHLAPKVSAFIDFIKGHIGSPPYWDAPCAELYAKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI4</accession>
    <name>B1KJI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324003.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1365"/>
    <dbReference type="EnsemblBacteria" id="ACA85657">
        <property type="protein sequence ID" value="ACA85657"/>
        <property type="gene ID" value="Swoo_1365"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1365"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_2_6"/>
    <dbReference type="OMA" id="VNLSDMY"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="52"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="370" mass="39767" checksum="B49907474A8B3A14" modified="2008-04-29" version="1" precursor="true">MKKSLIIIPIVLLITAIASFSGFSEAKKSADKTARAPRVVPVVTGSVEQHMLSQSLSLIGKLEADRSVFIAPEVAGKIKQINVVANQDIQAGQVLIQLEDARVQASVAEANAYLNDEKRKLKEFQKLIAKSAITQTEIDAQKASVDIAAARLAAALAELDFHYIKAPFSGTAGLLDFSLGKMVTAGSELLSLDDLSLMRLDLQVPENYLSLLSVGMKVNATNRAWPAEMFSGQVVAIDPRVNHETLSLKVRVSFDNASHKLKPGMLMSANLGLPAVSEPVIPVQAIEYSGTKRFVYVVGEDKLAKRTQVTLGARIKDEVVITQGVDIGEKIVVQGLVNMRDGLRVDELLAPKSHMTADADQGGNSSGDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJK6</accession>
    <name>B1KJK6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-monophosphate kinase</fullName>
            <shortName evidence="2">TMP kinase</shortName>
            <shortName evidence="2">Thiamine-phosphate kinase</shortName>
            <ecNumber evidence="2">2.7.4.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thiL</name>
        <name evidence="5" type="ordered locus">Swoo_1387</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + thiamine phosphate = ADP + thiamine diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15913"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine phosphate: step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiamine-monophosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.16" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324025.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1387"/>
    <dbReference type="EnsemblBacteria" id="ACA85679">
        <property type="protein sequence ID" value="ACA85679"/>
        <property type="gene ID" value="Swoo_1387"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1387"/>
    <dbReference type="eggNOG" id="COG0611">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046964_3_0_6"/>
    <dbReference type="OMA" id="HFRRDWS"/>
    <dbReference type="OrthoDB" id="1016556at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009030">
        <property type="term" value="F:thiamine-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02194">
        <property type="entry name" value="ThiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02128">
        <property type="entry name" value="TMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006283">
        <property type="entry name" value="ThiL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30270">
        <property type="entry name" value="PTHR30270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005303">
        <property type="entry name" value="Thiam_monoph_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01379">
        <property type="entry name" value="thiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="3">
        <location>
            <begin position="27"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="4">
        <location>
            <begin position="149"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="119"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="319" mass="34153" checksum="E58B16FE66A4C673" modified="2008-04-29" version="1">MKEFQLIEHFFAKQAQSRRDVELGIGDDCALVTPALNKSIAISCDTLVENVHFYPDIPPKALGYKSLAVNLSDLASMGAEPAWMTLALTLPEVDEQWLTSYSAGLFEAAEYYNIALVGGDTTLGPRSITITVNGQVQAGTGLTRSGARIGDWIYVTGTLGDSALGLDLIRGNRASSPEDADFLINRHYYPTPRVLAGQALRTLASSAIDLSDGLLSDIQHLLKQSGIGATIDVDLLPLSASLKNSVTEEEALSYALTGGEDYELLFSVPEAQKGALEIALANTGVSFAQIGQISTGDKLKLLRDGQPYTPINIGFEHFS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-01-20" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM2</accession>
    <name>T23O_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tryptophan 2,3-dioxygenase</fullName>
            <shortName evidence="1">TDO</shortName>
            <ecNumber evidence="1">1.13.11.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Tryptamin 2,3-dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophan oxygenase</fullName>
            <shortName evidence="1">TO</shortName>
            <shortName evidence="1">TRPO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophan pyrrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kynA</name>
        <name type="ordered locus">Swoo_1403</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-tryptophan + O2 = N-formyl-L-kynurenine</text>
            <dbReference type="Rhea" id="RHEA:24536"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
            <dbReference type="EC" id="1.13.11.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="1">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tryptophan 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324041.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJM2"/>
    <dbReference type="SMR" id="B1KJM2"/>
    <dbReference type="STRING" id="392500.Swoo_1403"/>
    <dbReference type="EnsemblBacteria" id="ACA85695">
        <property type="protein sequence ID" value="ACA85695"/>
        <property type="gene ID" value="Swoo_1403"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1403"/>
    <dbReference type="eggNOG" id="COG3483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063240_0_0_6"/>
    <dbReference type="OMA" id="WRWRNDH"/>
    <dbReference type="OrthoDB" id="1660023at2"/>
    <dbReference type="UniPathway" id="UPA00333">
        <property type="reaction ID" value="UER00453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004833">
        <property type="term" value="F:tryptophan 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01972">
        <property type="entry name" value="T23O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017485">
        <property type="entry name" value="Trp_2-3-dOase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004981">
        <property type="entry name" value="Trp_2_3_dOase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10138">
        <property type="entry name" value="PTHR10138"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03301">
        <property type="entry name" value="Trp_dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="SSF140959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03036">
        <property type="entry name" value="trp_2_3_diox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0223">Dioxygenase</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0823">Tryptophan catabolism</keyword>
    <feature type="chain" id="PRO_0000360134" description="Tryptophan 2,3-dioxygenase">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="55"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01972"/>
        </source>
    </evidence>
    <sequence length="286" mass="33077" checksum="B16B1ADC21670C1E" modified="2008-04-29" version="1">MVCPHNNPKQGNTREMEDSIHTDFNNDMSYGDYLCLEQVLSAQHPQSEVHDEMLFIIIHQTSELWLKLAGNELDTMIHNVQQGDFSHAFKVISRVKQILNQLTQSWNILSTLTPVDYLKFRDALGRSSGFQSYGYRKIEFLLGNKNADLIQVHESNEQVHSELQGILERPSLYDEVIRVLHKQGLPIDDSALNRDFTQPYQANESVLNAWLSVYRNADEHFELYELAEKLIDIEDAFQQWRFKHMYAVQRIIGNKMGTGGSSGVSFLKKALDISFFPELFELRTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJN0</accession>
    <name>B1KJN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:neurotransmitter symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1411</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324049.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1411"/>
    <dbReference type="EnsemblBacteria" id="ACA85703">
        <property type="protein sequence ID" value="ACA85703"/>
        <property type="gene ID" value="Swoo_1411"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1411"/>
    <dbReference type="eggNOG" id="COG0733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006855_3_0_6"/>
    <dbReference type="OMA" id="NERGMWN"/>
    <dbReference type="OrthoDB" id="376209at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="449" mass="48752" checksum="DBE0432DFB1872B8" modified="2008-04-29" version="1" precursor="true">MSVRGQFSSKLGFVLAAAGSAVGLGNIWGFPTQVASNGGAAFVLVYLILTFLLAYPILMAELVIGRYSQSNMVNALQGISQGPVSKLSGKLSGYWALTVVCLILSFYSIVAGWMLAYALASITDLLGLEQTSLWLTAFSTPRNLIFCFIFSLLTVGIVHKGVSDGIEKWSARLMPLLLILLISLIIFVATLDGAALGWEVYVIPDFAKILHSDLLISALGQAFFSLSLGVGTMLIYGSYVSKKENIVTLGAQVTLVDIGIAILAGMLIIPAMYVAQHNGVTIFTEAGELINGDRLIFTVIPELFTAMGDLGNVISFVFFSLMAIAAVTSSISMLEVPVAYTVENSSQPRSRVTWLIGAIIVLISTSIVFNFELLFGAVISFTTQYSQPLLGLVLSLFAGWVWRRDSILSELKLGCPEIEHSLFWKIWPSYVRFVCPVIILVMFYHSVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK19</accession>
    <name>B1KK19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Biotin/lipoyl attachment domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325542.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2933"/>
    <dbReference type="EnsemblBacteria" id="ACA87206">
        <property type="protein sequence ID" value="ACA87206"/>
        <property type="gene ID" value="Swoo_2933"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2933"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_7_7_6"/>
    <dbReference type="OMA" id="VVATWFV"/>
    <dbReference type="OrthoDB" id="1938042at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="17"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="78" mass="8533" checksum="50927FC039545F04" modified="2008-04-29" version="1">MAQAIIVPDDLWEDDDAEGVITAWLIDDSSEVQSGQLVADVMVEKIQYEIHSPFSGKISIISHEEEVVTKGCTIAEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK43</accession>
    <name>B1KK43_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4422</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327000.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4422"/>
    <dbReference type="EnsemblBacteria" id="ACA88674">
        <property type="protein sequence ID" value="ACA88674"/>
        <property type="gene ID" value="Swoo_4422"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4422"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028330_0_0_6"/>
    <dbReference type="OMA" id="CQYIGRL"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="252"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="396"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="637" mass="72920" checksum="C6CF7E877D1B9383" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK83</accession>
    <name>B1KK83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327040.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88714">
        <property type="protein sequence ID" value="ACA88714"/>
        <property type="gene ID" value="Swoo_4462"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4462"/>
    <dbReference type="eggNOG" id="ENOG502ZVZ2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1824012_0_0_6"/>
    <dbReference type="OMA" id="NERFRMS"/>
    <dbReference type="OrthoDB" id="2201803at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="141" mass="15852" checksum="1A1E309BF434A073" modified="2008-04-29" version="1">MNFRILFLTLLIASCSKESVQFEELALTISNEKAVNLDAGNWQVGGTLQLTNGLEWQKASFQNKRATCGSFLQALVLKNKLRLENASENELRAMSEELVLLLNERFRMSGNAAENEASFKHLKVSSEALSAIKLLNWYKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKB3</accession>
    <name>B1KKB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324099.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1465"/>
    <dbReference type="EnsemblBacteria" id="ACA85753">
        <property type="protein sequence ID" value="ACA85753"/>
        <property type="gene ID" value="Swoo_1465"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1465"/>
    <dbReference type="HOGENOM" id="CLU_2144129_0_0_6"/>
    <dbReference type="OMA" id="PACNTIP"/>
    <dbReference type="OrthoDB" id="2094058at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764991" evidence="1">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12497" checksum="F151B4C7DFF0D9BF" modified="2008-04-29" version="1" precursor="true">MKVLCCFLLLLVSTSSFSAAQWCKGKLERVYVDKPGNVYIFGNWRNDYTQICNVNSAWKGVSVELCKTWFSLAVTAKVSNGNVIVQYSDVPACNTIPNYSNAPSPNYVMLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC3</accession>
    <name>B1KKC3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324109.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1475"/>
    <dbReference type="EnsemblBacteria" id="ACA85763">
        <property type="protein sequence ID" value="ACA85763"/>
        <property type="gene ID" value="Swoo_1475"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1475"/>
    <dbReference type="HOGENOM" id="CLU_2261915_0_0_6"/>
    <dbReference type="OrthoDB" id="2203869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766757" evidence="1">
        <location>
            <begin position="20"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="103" mass="11435" checksum="D9D4FD1FCB538C94" modified="2008-04-29" version="1" precursor="true">MKLFIFLSCIIFCSFSTVAAPQYAGTVKGFYINNGKTVLVKLDTPTPACGDQTWPFQFSLSGEVAKGWMSMLLMARASEAQIGVGYAPNENGRCNVEYFYFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC4</accession>
    <name>B1KKC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324110.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1476"/>
    <dbReference type="EnsemblBacteria" id="ACA85764">
        <property type="protein sequence ID" value="ACA85764"/>
        <property type="gene ID" value="Swoo_1476"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1476"/>
    <dbReference type="eggNOG" id="ENOG5033IV8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179398_0_0_6"/>
    <dbReference type="OrthoDB" id="2012110at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767148" evidence="1">
        <location>
            <begin position="21"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="11722" checksum="D0685015E3546300" modified="2008-04-29" version="1" precursor="true">MKIVKYLLFLAFLLSSSAFARTDCPAAKVLHIQIEGSVILYMQEGSSWRRLGNLDEVGTAERYSALLAAQIAGLKVMVGYRSSSYNCAVTNYSEPAYIVRTYNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG1</accession>
    <name>B1KKG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324147.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1513"/>
    <dbReference type="EnsemblBacteria" id="ACA85801">
        <property type="protein sequence ID" value="ACA85801"/>
        <property type="gene ID" value="Swoo_1513"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1513"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_28_6"/>
    <dbReference type="OMA" id="FIHKPAS"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="165"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="33215" checksum="AF9FD83829EFD804" modified="2008-04-29" version="1">MSDKATILLVDDTRTNIELLAGCLQKTYNLKVAMNGKRCLELAESEPVPDLILLDVIMPDMDGYDVCRQLKDNSSTKDIPIMFVTGKDSDEDEELGLQLGAVDYITKPIRPAIVTARVGTQVILKQQSDTLRSMALHDQLTSLFNRHYLIEAANSKVARIKRHGGTLSLMMIDIDYFKLVNDKFGHQAGDTVLRAVASVLSSGSRKEDVVARFGGEEFVVLLDDCSILDADDKAEQLRSLIEQLIPEGISVTASFGIAELDPDGETFEHLLARADQAVYLAKEQGRNCVVQAKSELDIKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH0</accession>
    <name>B1KKH0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0125 (RnfH) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324156.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1522"/>
    <dbReference type="EnsemblBacteria" id="ACA85810">
        <property type="protein sequence ID" value="ACA85810"/>
        <property type="gene ID" value="Swoo_1522"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1522"/>
    <dbReference type="eggNOG" id="COG2914">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150721_1_0_6"/>
    <dbReference type="OMA" id="DMIHVEV"/>
    <dbReference type="OrthoDB" id="1921802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00460">
        <property type="entry name" value="UPF0125_RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005346">
        <property type="entry name" value="RnfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037021">
        <property type="entry name" value="RnfH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37483">
        <property type="entry name" value="PTHR37483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03658">
        <property type="entry name" value="Ub-RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="12533" checksum="E06D48C3F6C77DC2" modified="2008-04-29" version="1">MNIEQENFSVEVIYALPTQQKRVQVKVAPGTTCIEAVELSEMVNFFPEIDLEKVKLGIFSRLVKHSEVLVPGQRVEIYRPLIADPKDVRRKRAEKAKDEGRINKITGAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI5</accession>
    <name>B1KKI5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NrfJ-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324171.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1537"/>
    <dbReference type="EnsemblBacteria" id="ACA85825">
        <property type="protein sequence ID" value="ACA85825"/>
        <property type="gene ID" value="Swoo_1537"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1537"/>
    <dbReference type="eggNOG" id="ENOG502ZCF6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2304094_0_0_6"/>
    <dbReference type="OMA" id="EQMWMND"/>
    <dbReference type="OrthoDB" id="1846440at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765004" evidence="1">
        <location>
            <begin position="24"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11053" checksum="E9CE619080BAE0B9" modified="2008-04-29" version="1" precursor="true">MIAKLVKLLAVATLTLGISSAWAQGVVHEGTVVDTMNGGGYTYVQIKESDKTFWAAGPQVEISKGDKVVVQEQMWMNDFTSKTLNRTFDELLFVGRIDKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN8</accession>
    <name>TRUA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="1">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">truA</name>
        <name type="ordered locus">Swoo_2984</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325591.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKN8"/>
    <dbReference type="SMR" id="B1KKN8"/>
    <dbReference type="STRING" id="392500.Swoo_2984"/>
    <dbReference type="EnsemblBacteria" id="ACA87255">
        <property type="protein sequence ID" value="ACA87255"/>
        <property type="gene ID" value="Swoo_2984"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2984"/>
    <dbReference type="eggNOG" id="COG0101">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014673_0_2_6"/>
    <dbReference type="OMA" id="FLYGMVR"/>
    <dbReference type="OrthoDB" id="1075262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000097785" description="tRNA pseudouridine synthase A">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <sequence length="261" mass="29645" checksum="77C353940F0E8653" modified="2008-04-29" version="1">MRVALGIEYDGSKYFGWQRQVEVDSVQAQLERALSKVANEPISVHCAGRTDTGVHATGQVVHFDTDAIRKESAWTLGVNVSLPDDIAVRWAKVVDEDFHARFSATARRYRYMIYNYQLRPGILRSGVSHYRTHLDENKMHEAAQHFVGEHDFTSFRALHCQSKSPNRNVHEVNVTRQGMYICVDIKANAFLHHMVRNIVGSLIEIGLGHQSHEWIPELLALKDRSKAAPTAKPNGLYMVDVTYPEHFQLPKLALGPLFMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP3</accession>
    <name>B1KKP3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2989</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325596.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2989"/>
    <dbReference type="EnsemblBacteria" id="ACA87260">
        <property type="protein sequence ID" value="ACA87260"/>
        <property type="gene ID" value="Swoo_2989"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2989"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022176_2_0_6"/>
    <dbReference type="OMA" id="TTEMRTR"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="232"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="492"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="628" mass="71769" checksum="57FE7E95CD2929A7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW6</accession>
    <name>B1KKW6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secretion protein HlyD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327098.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4521"/>
    <dbReference type="EnsemblBacteria" id="ACA88772">
        <property type="protein sequence ID" value="ACA88772"/>
        <property type="gene ID" value="Swoo_4521"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4521"/>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_15_1_6"/>
    <dbReference type="OMA" id="VYIDANF"/>
    <dbReference type="OrthoDB" id="1680841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="46"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="3">
        <location>
            <begin position="103"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="153"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="351" mass="38133" checksum="0CEA8574FD396370" modified="2008-04-29" version="1">MSKSKLYIVVPLILALLISGGYYWWTQVRFIESTDNAYVEADISHISVKVPGYVVMTDITDNQHVEVGQLLAQLEDNQYEAKVAQSQAALESVKAEQQTLAAKVTLQDALINQAAAGVKAAESDHLRAEQQLNRTVQLKVKNYSSQDDVDQMQASFESAIAHLDEAKAALIAKQRELAVFKAQLQQVDANVVQARAGLKLAEIQLSDTQVRAPFSGIIGKRGAMKGQYVQPGQALYSLVPDGAVWITANFKETQIQHMQAGQQVKVTLDAFPDKAFTGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLAANQEMRIVPGLSAVVEVDTHEASINYAIAANAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKX0</accession>
    <name>B1KKX0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327102.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4526"/>
    <dbReference type="EnsemblBacteria" id="ACA88776">
        <property type="protein sequence ID" value="ACA88776"/>
        <property type="gene ID" value="Swoo_4526"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4526"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029425_2_2_6"/>
    <dbReference type="OMA" id="WQPGKRW"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="1">
        <location>
            <begin position="196"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="32695" checksum="CDD3E7446AAF0CA2" modified="2008-04-29" version="1">MSVTVFIQGRNGATRWQPGKRWLLLPVLLIAAGTGLYQHNAKQVQQQQTNADSERLARESQKQELIELKGATESQLAMLVTHVASMQAKVTRLEALGQQVAKNNQLEDQFDFSSAVGVGGLSEIGADIELEQLIADMDKLVSRIDNNNVQLSILETVSSNLHIDEERYISGRPIEKGWLSSPYGLRNDPFNGRRTMHKGIDFAGKEGTNVVATAGGVVTWAGKMFGYGELVEIDHGNGLRTRYGHNKSLSVAVGDVIAKGENIAKMGSTGRSTGPHVHYEVLRGGQQIDPQKYVYRKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL48</accession>
    <name>B1KL48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Two component, sigma54 specific, transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0088</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322738.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0088"/>
    <dbReference type="EnsemblBacteria" id="ACA84389">
        <property type="protein sequence ID" value="ACA84389"/>
        <property type="gene ID" value="Swoo_0088"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0088"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_6_6"/>
    <dbReference type="OMA" id="IVELTHH"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="16"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="154"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="459" mass="51714" checksum="8E13411ABBEC2A88" modified="2008-04-29" version="1">MSQSNKELKPLPSAVSVLIVDDEPGMRSFLKKALSKKFALVETASSVEDAEQLRSRCHFDLLIVDIRLPGRSGIEWHEALNDQERRSDIIFMTGYADMDVAIKALRAGASDFIMKPFHLEQMMKAVDRCIERRLLKRENLMLRREVSIGQSSTIIGSSDAMQEVKHIIERVAPTNAVILIEGESGTGKELVARQLHLLSGRQGPFVPVNCGAIAPELLESELFGHCAGAFTGAKGNREGLFSFASGGTIFLDEIGEMPLKMQTALLRVLEQRTIRPVGSEKETNIDVRVLAATNRKLAEEVEAGHFRRDLYYRLNVLDILIPPLRERPEDVVELTHHFTRQLASELGVKEVVWSHEDMLKLQQHEWPGNIRELRNMIERCILLGKPPAEYWKQQPKAEVVGESGYPLNWCLKEVEKHHVTQVVDAHNGNKSAAARDLGVSRKTLDRKYKEWFDSESAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL54</accession>
    <name>B1KL54_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0094</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322744.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0094"/>
    <dbReference type="EnsemblBacteria" id="ACA84395">
        <property type="protein sequence ID" value="ACA84395"/>
        <property type="gene ID" value="Swoo_0094"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0094"/>
    <dbReference type="eggNOG" id="COG4206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_18_0_6"/>
    <dbReference type="OMA" id="AAEYQYQ"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767451" evidence="6">
        <location>
            <begin position="26"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="52"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="231"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="649" mass="71908" checksum="7AEA92B3DEF0B74C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL63</accession>
    <name>B1KL63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84404">
        <property type="protein sequence ID" value="ACA84404"/>
        <property type="gene ID" value="Swoo_0103"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0103"/>
    <dbReference type="eggNOG" id="ENOG5031F82">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_213954_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="53" mass="5822" checksum="BDA2912983843B4F" modified="2008-04-29" version="1">MKKWLIVLSCTVFVAASLLTSGLTRALIDLVAFASLLWIVLVMRSDPSSKQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG1</accession>
    <name>B1KLG1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar hook protein FlgE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324232.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1600"/>
    <dbReference type="EnsemblBacteria" id="ACA85886">
        <property type="protein sequence ID" value="ACA85886"/>
        <property type="gene ID" value="Swoo_1600"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1600"/>
    <dbReference type="eggNOG" id="COG1749">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013687_2_0_6"/>
    <dbReference type="OMA" id="NWVAFYA"/>
    <dbReference type="OrthoDB" id="704242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.98.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011491">
        <property type="entry name" value="Falgellar_hook_FlgE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037058">
        <property type="entry name" value="Falgellar_hook_FlgE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07559">
        <property type="entry name" value="FlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="3"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="FlaE" evidence="8">
        <location>
            <begin position="182"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="374"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="453" mass="47191" checksum="3CB2BF68BD3A1B27" modified="2008-04-29" version="1">MSFNIALSGISAAQKDLNTTANNIANVNSIGFKESRAEFADVYANSIFANSKTAVGGGATTSQVAQQFHQGSLQFTNNALDMAINGGGFFVTSSSLDSQDHTFTRAGAFKVDSNNYLVDSQGNFLQTFGVDKDGNSTSVSLTTTSPVIIPDTAGSPKMTDEIGIQMNLNAGDDTLDPAAFDPNDRDTYNNSTAVTLYDSLGEPHIMTTYFVRPPQAAYTGASNWVAFYAVDGKQVDLAGPAGTYQTDTTGDGNADSSGSATTAGGWKGSVLTYNDTGAYVGSDPAVVTTEELGVNGAGVLGPGADGTQTLAVKYNNPTQYASTFEVTELTQDGTTVGRLTNVEVGADGLINASYSNGSTVPLARVALARFANEQGLTQVGNTSWKASLDSGLALAGEANSGTFGSIRSSALEQSNVDLTTELVDLISAQRNFQANSRTLEVNNTLQQTVLQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH1</accession>
    <name>B1KLH1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar protein FlaG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324242.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1610"/>
    <dbReference type="EnsemblBacteria" id="ACA85896">
        <property type="protein sequence ID" value="ACA85896"/>
        <property type="gene ID" value="Swoo_1610"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1610"/>
    <dbReference type="eggNOG" id="COG1334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120910_4_1_6"/>
    <dbReference type="OMA" id="VRQIPNA"/>
    <dbReference type="OrthoDB" id="1913585at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005186">
        <property type="entry name" value="FlaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035924">
        <property type="entry name" value="FlaG-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37166">
        <property type="entry name" value="PTHR37166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03646">
        <property type="entry name" value="FlaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160214">
        <property type="entry name" value="SSF160214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14102" checksum="5BE764B2A1C13C92" modified="2008-04-29" version="1">MDINFTNSSSTATAKIEISTTPVKSTAAESSELERRATIQAVEETEKETEVQSKTSQAEMQQLVEDLSDMMSVMRKGLAFKIDESSGKNIVSVMDVDSGDIIRQIPNEEALKLAQKLSEVTGLLMKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP6</accession>
    <name>B1KLP6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325679.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3072"/>
    <dbReference type="EnsemblBacteria" id="ACA87343">
        <property type="protein sequence ID" value="ACA87343"/>
        <property type="gene ID" value="Swoo_3072"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3072"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018914_1_0_6"/>
    <dbReference type="OMA" id="MPVDEIH"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="616" mass="69558" checksum="F1F1796CB73A00BA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLT5</accession>
    <name>B1KLT5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Lon protease</fullName>
            <ecNumber evidence="5 6">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lon</name>
        <name evidence="14" type="ordered locus">Swoo_3111</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6 9 10">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="5 6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325718.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3111"/>
    <dbReference type="MEROPS" id="S16.001"/>
    <dbReference type="EnsemblBacteria" id="ACA87382">
        <property type="protein sequence ID" value="ACA87382"/>
        <property type="gene ID" value="Swoo_3111"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3111"/>
    <dbReference type="eggNOG" id="COG0466">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004109_4_3_6"/>
    <dbReference type="OMA" id="GAWQVVD"/>
    <dbReference type="OrthoDB" id="128102at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="13">
        <location>
            <begin position="11"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="12">
        <location>
            <begin position="592"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="190"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="679"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="722"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <begin position="356"/>
            <end position="363"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="785" mass="87568" checksum="A6DC07A1308DFFE3" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLT6</accession>
    <name>CLPX_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpX</name>
        <name type="ordered locus">Swoo_3112</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325719.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLT6"/>
    <dbReference type="SMR" id="B1KLT6"/>
    <dbReference type="STRING" id="392500.Swoo_3112"/>
    <dbReference type="EnsemblBacteria" id="ACA87383">
        <property type="protein sequence ID" value="ACA87383"/>
        <property type="gene ID" value="Swoo_3112"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3112"/>
    <dbReference type="eggNOG" id="COG1219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014218_8_2_6"/>
    <dbReference type="OMA" id="HYKRVQA"/>
    <dbReference type="OrthoDB" id="718259at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000098001" description="ATP-dependent Clp protease ATP-binding subunit ClpX">
        <location>
            <begin position="1"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="ClpX-type ZB" evidence="2">
        <location>
            <begin position="4"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="121"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <sequence length="426" mass="46550" checksum="3B17A84F597F7FE7" modified="2008-04-29" version="1">MSDNKSTGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVIGQEKAKKVLSVAVYNHYKRLKNAGPKDGVELGKSNILLIGPTGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDTSKILFVCGGAFSGLEKVIEQRSHTGTGIGFGAQVKGEDDKATISDTLMQVEPEDLVKYGLIPEFIGRLPVLATLAELDDAALIQILSEPKNALTKQFAALFEMEDVELEFREDALKAIALKAKTRKTGARGLRSIVEGILLDIMYDLPSTDNVAKVVIDESVVKGESTPILIYENSESQAASAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM35</accession>
    <name>B1KM35_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoA</name>
        <name evidence="13" type="ordered locus">Swoo_4665</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327239.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4665"/>
    <dbReference type="EnsemblBacteria" id="ACA88915">
        <property type="protein sequence ID" value="ACA88915"/>
        <property type="gene ID" value="Swoo_4665"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4665"/>
    <dbReference type="eggNOG" id="COG0202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053084_0_0_6"/>
    <dbReference type="OMA" id="LMKFRNF"/>
    <dbReference type="OrthoDB" id="662686at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="23"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="248"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA88915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="329" mass="36186" checksum="F4898E79C1B8DC93" modified="2008-04-29" version="1">MQGSVTEFLRPRLVDIEQVNPTRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDVLEILLNLKGLAVVVEGKDEAMLTLSKSGAGPVTAADITHDGDVTIMNPDHVICHLTGNNDVSMRIRVERGRGYVPASARAQTEDDERPIGRLLVDSSFSPVARIAYNVEAARVEQRTDLDKLVIDMTTNGTIDPEEAIRRSATILAEQLDAFVELRDVTEPELKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASLADDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM39</accession>
    <name>B1KM39_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription elongation factor GreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Transcript cleavage factor GreB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">greB</name>
        <name evidence="7" type="ordered locus">Swoo_0151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GreA/GreB family. GreB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322801.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0151"/>
    <dbReference type="EnsemblBacteria" id="ACA84452">
        <property type="protein sequence ID" value="ACA84452"/>
        <property type="gene ID" value="Swoo_0151"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0151"/>
    <dbReference type="eggNOG" id="COG0782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101379_3_0_6"/>
    <dbReference type="OMA" id="DQIFFGA"/>
    <dbReference type="OrthoDB" id="1591985at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00930">
        <property type="entry name" value="GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006358">
        <property type="entry name" value="Tscrpt_elong_fac_GreB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01461">
        <property type="entry name" value="greB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="5">
        <location>
            <begin position="81"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="18762" checksum="8616F3B5718770F4" modified="2008-04-29" version="1">MTAMLITRKGWQALDKELKYLWKEYRPEITKKVQEAAAQGDRSENADYTYNKRLLRQIDSRVRYLVKRVEDLTIVDYSPQQEGKVFFGAWVELENESGDVVQYRIVGKDELDTKLGYITIDSPMARALIGKQVDDEVVVKTPSGAKEWYVNKIQYKAFKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME2</accession>
    <name>B1KME2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleotide sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324286.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1654"/>
    <dbReference type="EnsemblBacteria" id="ACA85940">
        <property type="protein sequence ID" value="ACA85940"/>
        <property type="gene ID" value="Swoo_1654"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1654"/>
    <dbReference type="eggNOG" id="COG0677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023810_3_1_6"/>
    <dbReference type="OMA" id="GHCLPID"/>
    <dbReference type="OrthoDB" id="295459at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="319"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="426" mass="47156" checksum="D03EA5BAE71C6F75" modified="2008-04-29" version="1">MIVSLDNVKIGIIGLGYVGLPLAVEFGKKSPTIGFDINEGRISELSYGHDSTLECSHQELAEATCLRYTASLSDLKECNVYIVTVPTPIDEHKQPDLTPLVKASEALGAVVSEGDIIIYESTVYPGATEEECISVVEKVSGLKFNQNFFAGYSPERINPGDKEHRVTNILKVTSGSTPEVAEFVDQLYKSIIVAGTHKASSIKVAEAAKVIENTQRDVNIALINELSIIFNKLDIDTLEVLEAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQTVGYHPEMILAGRRLNDGMGQYVVSQLVKKMLKKRLHVEGANVLVMGLTFKENCPDLRNTKVVDIVSELKEYNINVDIVDPWCSNDEAEHEYGLSLCEKPKANNYDAIIMAVAHNEFREMGAEKIHVLGKTEHVLYDLKYILDKESVDMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME6</accession>
    <name>B1KME6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1658"/>
    <dbReference type="EnsemblBacteria" id="ACA85944">
        <property type="protein sequence ID" value="ACA85944"/>
        <property type="gene ID" value="Swoo_1658"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1658"/>
    <dbReference type="eggNOG" id="ENOG50319Y8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620610_0_0_6"/>
    <dbReference type="OMA" id="NQVLMQR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="430" mass="49275" checksum="FC825D8D1280E31C" modified="2008-04-29" version="1">MKLISYRYLPLNIFLLYTFFVMFALFFGPAQFRNMNFLYLASFLIINTFIFVFFFIAGAKGIVKWEHKKSKNNFIEGSFFKFFLYSGLLLSIVAWGDFFVSGKSISISNMGTNYVDGYDGYVRGSSSIGFSYILNIFSVSLQTLSLLFIFSNYIFLNKKQKLIACFVIFTYLIINVLVSGKQKYLGDIVIFFVYSYLIFSAVQNKRFSVSKILNYCFVFSVVVFSFSYILTSRYAAIDIDGSNIATALNSHVYWDSESIIIKIFGNTFGFGIGMFLGYFTNGLYGLNLALQLPFEWTYFLGNSYSLAKIVETAISSPGLILQHSYPFRAEELGWGLDKWHSAFSWLASDLTFPGTLCFMAFFSFSYARVWIASINNSNPFARPLFIYLSVGIVFVYSNNQLVHSLSGVFVLFALVIMYFIYKFQSRQVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH7</accession>
    <name>B1KMH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324321.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1690"/>
    <dbReference type="EnsemblBacteria" id="ACA85975">
        <property type="protein sequence ID" value="ACA85975"/>
        <property type="gene ID" value="Swoo_1690"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1690"/>
    <dbReference type="eggNOG" id="COG0608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_873774_0_0_6"/>
    <dbReference type="OMA" id="HYDVFNG"/>
    <dbReference type="OrthoDB" id="1394235at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="322" mass="35321" checksum="0A8D480F77DB778C" modified="2008-04-29" version="1">MNYDIFNGDADGIIALLQLRLAQPHTATLVTGVKRDIELLEPLTKKYSLTAQDNLTVLDISMEKNRVGLLFALESGAKVFYSDHHRSGKIPQTVNLDAHIDLDANTCTSLIIDDYLQGEFHLWAIVAAYGDNLIAKADGLSTKAGLSLSQAKQLNELGTLINYNGYGAHIDDLHFHPAELYKALLKYPDPFDVIADLSSPFHRLKKAYRHDMDRALAVKPFYQSETLSLFELEDAPWSRRVSGVFSNQLANQDTGSAHGVFTENSDGSFTVSLRAPLSNKQGAGDICSQFATGGGRAAAAGINQLPRVDIPRFTQTVESYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMU3</accession>
    <name>B1KMU3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3201</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325807.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3201"/>
    <dbReference type="EnsemblBacteria" id="ACA87471">
        <property type="protein sequence ID" value="ACA87471"/>
        <property type="gene ID" value="Swoo_3201"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3201"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_10_6"/>
    <dbReference type="OMA" id="VGAAKEW"/>
    <dbReference type="OrthoDB" id="490746at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="14"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="501" mass="54439" checksum="451AF323386238E8" modified="2008-04-29" version="1">MTTQVKHYIDGQFIEGQGKQKISVTNPANNQSIAVVNAATVSEVETAIASAKLAFKSWKEVPVSERARVMFNYQHLLKAHHDELATILAQETGKTFDDAKGDVWRGIEVAEHACNIATLMMGETVENVARSIDTYSYTQPLGVCAGITPFNFPAMIPLWMFPLAIACGNTFVLKPSEQDPMTPQRLVELFEEAGAPKGVLQLIHGDKVAVDVLLNHQDIKAISFVGSVGVGQYIYKTGTDNLKRVQAFAGAKNHCVIMPDANKQQVINNLVGASVGAAGQRCMALSVAIFVGAAKEWIPELKEAIAKVKPGLWDDKEAAYGPVISPAAKARVLSLIEQGKSEGAECLLDGSDFTVEGYEAGNWVGPTMFTKVTTEMSIYKEEIFGPVLCCMESETLEEAIEVVNNSPYGNGTSIFTASGAAARKYQHEIEVGQVGINVPIPVPLPFFSFTGWKGSFYGDQHAYGKQAVRFYTETKTITSRWFESQISTAEHAAPNMTIDLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMW1</accession>
    <name>RS13_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsM</name>
        <name type="ordered locus">Swoo_4668</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327242.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMW1"/>
    <dbReference type="SMR" id="B1KMW1"/>
    <dbReference type="STRING" id="392500.Swoo_4668"/>
    <dbReference type="EnsemblBacteria" id="ACA88918">
        <property type="protein sequence ID" value="ACA88918"/>
        <property type="gene ID" value="Swoo_4668"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4668"/>
    <dbReference type="eggNOG" id="COG0099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103849_1_2_6"/>
    <dbReference type="OMA" id="YRGLRHK"/>
    <dbReference type="OrthoDB" id="1772647at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000141311" description="30S ribosomal protein S13">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="118" mass="13260" checksum="84C9681EE3E42EF2" modified="2008-04-29" version="1">MARIAGINIPDHKHTVIALTGIFGIGRTRARAICAATSVAEDAKIKELSEAQIDTLREAVAEYTVEGDLRREVSMNIKRLMDLGCYRGIRHRRSLPLRGQRTKTNARTRKGPRKPIRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ1</accession>
    <name>RL7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplL</name>
        <name type="ordered locus">Swoo_4698</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327267.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMZ1"/>
    <dbReference type="SMR" id="B1KMZ1"/>
    <dbReference type="STRING" id="392500.Swoo_4698"/>
    <dbReference type="EnsemblBacteria" id="ACA88948">
        <property type="protein sequence ID" value="ACA88948"/>
        <property type="gene ID" value="Swoo_4698"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4698"/>
    <dbReference type="eggNOG" id="COG0222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_3_2_6"/>
    <dbReference type="OMA" id="LEDKWGV"/>
    <dbReference type="OrthoDB" id="1822695at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000121490" description="50S ribosomal protein L7/L12">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <sequence length="122" mass="12432" checksum="DD715F421142D84F" modified="2008-04-29" version="1">MSITKDQILEAFAEMSVMEVVELIEAMEEKFGVSAAAAVVAGGAEGGAAAAEQTEFDVMMTSFGANKVAVIKALRGATGLGLKEAKAMAESAPVAVKEGLEKAEAEALKAELEAAGAEVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN06</accession>
    <name>B1KN06_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenide, water dikinase</fullName>
            <ecNumber evidence="5">2.7.9.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenium donor protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selD</name>
        <name evidence="8" type="ordered locus">Swoo_4713</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Synthesizes selenophosphate from selenide and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + hydrogenselenide = AMP + 2 H(+) + phosphate + selenophosphate</text>
            <dbReference type="Rhea" id="RHEA:18737"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:29317"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the selenophosphate synthase 1 family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4713"/>
    <dbReference type="EnsemblBacteria" id="ACA88963">
        <property type="protein sequence ID" value="ACA88963"/>
        <property type="gene ID" value="Swoo_4713"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4713"/>
    <dbReference type="eggNOG" id="COG0709">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032859_0_1_6"/>
    <dbReference type="OMA" id="DNEPKYG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00625">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023061">
        <property type="entry name" value="SelD_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="PTHR10256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036407">
        <property type="entry name" value="Selenphspht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="6">
        <location>
            <begin position="55"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="174"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="144"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="351" mass="37031" checksum="FAC9CDFDD01715F1" modified="2008-04-29" version="1">MDFVPMLQSEIKLTEYSHGAGCGCKISPKVLSTILASQLPLFEDPNILVGNQTRDDAAVYKLNDETGIISTTDFFMPIVDDPFTFGRIAATNAISDIYAMGGTPMMAIAILGWPINTLPAEVAQQVVDGGRQACADAGIMLAGGHSIDSPEPIFGLAVSGQIPLSELKQNDTAKSGDKLYLTKPLGIGILTTAQKQKKIAPEDTQIAVDAMCQLNKVGALAAKISGVNAMTDVTGFGLAGHLIEMCQGAKLNAQISVPTLPLLPKAEKYLELGCIPGGTHRNFESYCEHLPQLTDIEKAIICDPQTSGGLLLSVSSDAEAELTALLKTHGITANCIGTLTHSEQPTLVELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN55</accession>
    <name>B1KN55_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322901.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84552">
        <property type="protein sequence ID" value="ACA84552"/>
        <property type="gene ID" value="Swoo_0251"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0251"/>
    <dbReference type="eggNOG" id="ENOG5031E7Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169028_0_0_6"/>
    <dbReference type="OMA" id="MIYSQFQ"/>
    <dbReference type="OrthoDB" id="2006150at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="13584" checksum="6F5946A6CD11662A" modified="2008-04-29" version="1">MIYSQFQQSPFQTRFSGARGWMAFAIGLAVITLTLIALPFVLLIGAISFILLSLFGRIFMKRQLARFRQQQAQAGQAKQESGFYQSDSAQDQGPFQEARFGTERHQAKPHQGRTFEHDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE9</accession>
    <name>B1KNE9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oxaloacetate decarboxylase beta chain</fullName>
            <ecNumber evidence="12">7.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_1741</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:57724"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="EC" id="7.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7 12">Heterotrimer of an alpha, a beta and a gamma subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 12">Belongs to the GcdB/MmdB/OadB family.</text>
    </comment>
    <dbReference type="EC" id="7.2.4.2" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324372.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1741"/>
    <dbReference type="EnsemblBacteria" id="ACA86026">
        <property type="protein sequence ID" value="ACA86026"/>
        <property type="gene ID" value="Swoo_1741"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1741"/>
    <dbReference type="eggNOG" id="COG1883">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036168_0_0_6"/>
    <dbReference type="OMA" id="MNFIYYM"/>
    <dbReference type="OrthoDB" id="662061at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015451">
        <property type="term" value="F:decarboxylation-driven active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005661">
        <property type="entry name" value="OadB_MmdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35806">
        <property type="entry name" value="PTHR35806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03977">
        <property type="entry name" value="OAD_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015658">
        <property type="entry name" value="MmdB_OadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01109">
        <property type="entry name" value="Na_pump_decarbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="9 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR015658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="39444" checksum="964340822AEA2D9C" modified="2008-04-29" version="1">MEGLLTLWHDTGLYNFQIGQLIMMFIGGLLLYLAISKRYEPLLLLPIGFGAILANIPMAGFTEEGGLLWYIYHIGIETGVFPLIIFMGVGALTDFGALIANPKVLLLGAAAQFGIFSTLFGAIALNMVPGFEFSLSDAAAIAIIGGADGPTAIFLASRLAPDLLGAIAVAAYSYMALVPLIQPPIMKALTTHEERSIVMEQMRDVSKIEKIIFPLMVLALTVMFLPAATPLVGMFCLGNIMRESGVVDRLSSTAQNELINIVTIFLGLAVGSKLSAEKFLNLETLGILALGAIAFSIGTASGVMMAKLMGRFSRSPINPLIGAAGVSAVPMAARVANRVGLEANPHNFLLMHAMGPNVAGVLGSAVAAGILLAIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI4</accession>
    <name>B1KNI4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Iron-sulfur cluster assembly scaffold protein IscU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1777</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the NifU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324407.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1777"/>
    <dbReference type="EnsemblBacteria" id="ACA86061">
        <property type="protein sequence ID" value="ACA86061"/>
        <property type="gene ID" value="Swoo_1777"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1777"/>
    <dbReference type="eggNOG" id="COG0822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079283_5_0_6"/>
    <dbReference type="OMA" id="YKNPRNY"/>
    <dbReference type="OrthoDB" id="1793654at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISC_FeS_clus_asmbl_IscU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="4">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="13647" checksum="65156F5D4BF6B306" modified="2008-04-29" version="1">MAYSEKVLDHYENPRNVGSFDKNDPSVVTGMVGAPACGDVMKLQLRIDADGVIEDAKFKTYGCGSAIASSSLVTEWVKGKTIEEAAAIKNTDIAEELALPPVKIHCSILAEDAIKAAIDDYKSKQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNT8</accession>
    <name>B1KNT8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3276</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325882.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3276"/>
    <dbReference type="EnsemblBacteria" id="ACA87546">
        <property type="protein sequence ID" value="ACA87546"/>
        <property type="gene ID" value="Swoo_3276"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3276"/>
    <dbReference type="eggNOG" id="COG0575">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037294_1_2_6"/>
    <dbReference type="OMA" id="WEWGRLN"/>
    <dbReference type="OrthoDB" id="1533756at2"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="285" mass="31217" checksum="90E17D73D39D599D" modified="2008-04-29" version="1">MLKQRIITAIWLIPLVLGAIFGLPTEYFSWALIGVFLIAAKEWGQIIDKRCQMTQWSFTITIGVLLVALNLFVPSDELWFKGQLHPVFLSIILIGAIWWAVAFLLVISFPKSAALWQKSHMFKSMFGQLTLIPCYTALVALKGLSTQVDPYYGGSLVFLVMLVVWATDSGAYFAGKALGRTKLMPNVSPAKTIEGLVGGLAMSMLIVVGIMQVSPEQELGLLVCVTLFVALVSAVGDLSESMFKRVAQIKDSGKILPGHGGVLDRIDSLTAALPIFTLIYIAFWM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP81</accession>
    <name>GMHA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="1">5.3.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gmhA</name>
        <name type="ordered locus">Swoo_0350</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIS family. GmhA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323000.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP81"/>
    <dbReference type="SMR" id="B1KP81"/>
    <dbReference type="STRING" id="392500.Swoo_0350"/>
    <dbReference type="EnsemblBacteria" id="ACA84651">
        <property type="protein sequence ID" value="ACA84651"/>
        <property type="gene ID" value="Swoo_0350"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0350"/>
    <dbReference type="eggNOG" id="COG0279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080999_3_1_6"/>
    <dbReference type="OMA" id="DVHICVP"/>
    <dbReference type="OrthoDB" id="1571626at2"/>
    <dbReference type="UniPathway" id="UPA00041">
        <property type="reaction ID" value="UER00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008968">
        <property type="term" value="F:D-sedoheptulose 7-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001061">
        <property type="term" value="P:D-glycero-D-manno-heptose 7-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00067">
        <property type="entry name" value="GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004515">
        <property type="entry name" value="Phosphoheptose_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000197030" description="Phosphoheptose isomerase">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="1">
        <location>
            <begin position="34"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="49"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="91"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00067"/>
        </source>
    </evidence>
    <sequence length="195" mass="20769" checksum="A5A6DFA8C0324334" modified="2008-04-29" version="1">MLERIKDSFTHSIQTKIDASEALPESIAKAAEMMVHCLLGGNKILACGNGGSAGDAQHFSAELLNRFEVERPPLPAIALTTDTSTITAIANDYSYDEIFSKQILALGQPGDILLAISTSGHSGNVIKAIEAALSRDMTIVALTGKDGGPMAGLLSINDVEIRVPSNSTARIQEVHLLAIHCLCDNIDRTLFPQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP99</accession>
    <name>B1KP99_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323018.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0369"/>
    <dbReference type="EnsemblBacteria" id="ACA84669">
        <property type="protein sequence ID" value="ACA84669"/>
        <property type="gene ID" value="Swoo_0369"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0369"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_7_0_6"/>
    <dbReference type="OMA" id="VDPRSYM"/>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="3"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="402" mass="43998" checksum="98BFB1D046CF3226" modified="2008-04-29" version="1">MSRVVIVGGGAAGLELASLLGRSVNKQDEVILVEGETHHYWKPRFHEIAAGTFDNDLDSLCYFSHGAKNGYRHYQGRMTNINREEKQLVVYKTNGETDTLAYDYLVIAVGAISNDFATKGALEHSLFLDTPEQARESWQQISALLRSGEQRTINIVGAGATGLELAAELAKVSGKLERNPHAARLTINLIEAADRVLPNSPLKMSQQAQSRLEKFNVNLLLNTRIASVDKQGMTTSEGITLDADLQFWAAGIKAPDWLKNIGGLESNNANQLVVQQTLATTQDPSIFSLGDCAAIPQADGSTVPPKAQAANRAAVHLAKSLLGLMQGKTLTPFVYKDGGMVVAIGHNYAISTMMNDRLILKGRLVRRLYDTIFRLHQKTVSGFLTMSRLIIAKRLKCIFQPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD4</accession>
    <name>B1KPD4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323053.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84704">
        <property type="protein sequence ID" value="ACA84704"/>
        <property type="gene ID" value="Swoo_0405"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0405"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1501363_0_0_6"/>
    <dbReference type="OMA" id="GRYYMTY"/>
    <dbReference type="OrthoDB" id="2018542at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764720" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="9"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="22795" checksum="C209AFECA4EEBA3F" modified="2008-04-29" version="1" precursor="true">MKKQSLALAALLATAMSAPTMAADWFVGGAVGAQKNVYKSSSTAADSVDPGFNAQADYWKNNDTNAIYEVRAGAYLNDNNRVYGTYSYNSDDYTKQQSVLMSYDYLVGLGESNKLNWFIGATAGVNHTSPSTDHIGSSNNFVWGGQTGLMYKINDNLSTEIGYRYLRQDVNETNQFSISNGVEAVTNVTVNNSLNDSQQVYLGLDYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPN9</accession>
    <name>B1KPN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324538.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1908"/>
    <dbReference type="EnsemblBacteria" id="ACA86192">
        <property type="protein sequence ID" value="ACA86192"/>
        <property type="gene ID" value="Swoo_1908"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1908"/>
    <dbReference type="eggNOG" id="COG1794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055360_1_0_6"/>
    <dbReference type="OMA" id="TNTMHLI"/>
    <dbReference type="OrthoDB" id="1359310at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004380">
        <property type="entry name" value="Asp_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF7">
        <property type="entry name" value="PTHR21198:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00035">
        <property type="entry name" value="asp_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="231" mass="25033" checksum="501622F85656B3BC" modified="2008-04-29" version="1">MKTIGLIGGMSWESTLSYYQALNLGVKAELGGLHSAKIVLVSVDFAEIEKLQHLGEWDKTAAILSEAASGLEAANADFFMICTNTMHKVADEVQAKVNIPLLHIADATAELLVKDGIKKVGLLGTQFTMAESFYKGRLTEKYGIEVLTPSDDDQSIIHRVIYDELCQGVVNAQSRSAYVEIIEKLRDNGADAVILGCTEIAMLVKETDTNVPLYDTTAIHAEAAVKIALDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ1</accession>
    <name>B1KPQ1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tricorn protease homolog</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_3315</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Degrades oligopeptides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S41B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325920.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3315"/>
    <dbReference type="EnsemblBacteria" id="ACA87584">
        <property type="protein sequence ID" value="ACA87584"/>
        <property type="gene ID" value="Swoo_3315"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3315"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4946">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005503_0_0_6"/>
    <dbReference type="OMA" id="YLHVPDM"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028204">
        <property type="entry name" value="Tricorn_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029414">
        <property type="entry name" value="Tricorn_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012393">
        <property type="entry name" value="Tricorn_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43253">
        <property type="entry name" value="PTHR43253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14684">
        <property type="entry name" value="Tricorn_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14685">
        <property type="entry name" value="Tricorn_PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036421">
        <property type="entry name" value="Tricorn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766934" description="Tricorn protease homolog" evidence="10">
        <location>
            <begin position="25"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="11">
        <location>
            <begin position="774"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="12">
        <location>
            <begin position="842"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="756"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="978"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="1036"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer; via amide nitrogen" evidence="9">
        <location>
            <position position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036421-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036421-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1097" mass="121524" checksum="441FD6C273A4A1EE" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPV6</accession>
    <name>B1KPV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325974.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3370"/>
    <dbReference type="EnsemblBacteria" id="ACA87639">
        <property type="protein sequence ID" value="ACA87639"/>
        <property type="gene ID" value="Swoo_3370"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3370"/>
    <dbReference type="eggNOG" id="ENOG50331S4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100616_1_0_6"/>
    <dbReference type="OMA" id="GNVNILW"/>
    <dbReference type="OrthoDB" id="1666830at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021557">
        <property type="entry name" value="DUF3016"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11454">
        <property type="entry name" value="DUF3016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767545" evidence="1">
        <location>
            <begin position="24"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="20509" checksum="4D09A51A62324E7C" modified="2008-04-29" version="1" precursor="true">MKYVFSLLTLIFMAILTGCTSTAENAPVDNYITHDGNLAIIWKNPNQYTDIESTIWLQSKFTPYLFTELTEELGKQVNPVLGKDQKLDIMVTNLDLAGDVQPTFGASADDIRVVSELYPPRINFDYSLSQNGKVIKSGSEKLQNMSFLFGIQPITSQPFAYESDLLKKWFKKEIKPDLIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ75</accession>
    <name>B1KQ75_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome bo(3) ubiquinol oxidase subunit 1</fullName>
            <ecNumber evidence="8">7.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Cytochrome o ubiquinol oxidase subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Oxidase bo(3) subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Ubiquinol oxidase polypeptide I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquinol oxidase subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Swoo_0432</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 a ubiquinol + n H(+)(in) + O2 = 2 a ubiquinone + n H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30251"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="EC" id="7.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a quinone</name>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme o</name>
            <dbReference type="ChEBI" id="CHEBI:24480"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.3" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323079.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0432"/>
    <dbReference type="EnsemblBacteria" id="ACA84730">
        <property type="protein sequence ID" value="ACA84730"/>
        <property type="gene ID" value="Swoo_0432"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0432"/>
    <dbReference type="eggNOG" id="COG0843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011899_7_1_6"/>
    <dbReference type="OMA" id="FWGKMSF"/>
    <dbReference type="OrthoDB" id="316745at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014207">
        <property type="entry name" value="Cyt_c_ubiqinol_oxidase_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02843">
        <property type="entry name" value="CyoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="17" id="KW-0349">Heme</keyword>
    <keyword evidence="17" id="KW-0408">Iron</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="10 17 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="17" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="595"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="19">
        <location>
            <begin position="41"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00014691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACA84730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="661" mass="73799" checksum="0C1E20148B44FC34" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ82</accession>
    <name>B1KQ82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323086.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0439"/>
    <dbReference type="EnsemblBacteria" id="ACA84737">
        <property type="protein sequence ID" value="ACA84737"/>
        <property type="gene ID" value="Swoo_0439"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0439"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_1_6"/>
    <dbReference type="OMA" id="FIAVMEN"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="133"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="267" mass="29942" checksum="5599110001153095" modified="2008-04-29" version="1" precursor="true">MSNIAIALVTTGLLGLISAVMPTHQICNIPDHQHKGWVLLLTMIFMFIFGYLGYIWMLIDRDIGTLELIVATIFCGGGGFVFVISRMSKETIFKLQQTIHEKHYQAHHDLLTNLANRHQFYEELDSLISNEHHVFSCLMMDLNDFKMVNDTLGHAEGDHVLQVVAKRIQRILPKRGVAARLGGDEFAVVLPGMTLQGAIEISKTIQDTLSKDIQCENHALVIGISIGIAEYPKHGTNKKEIMKHADIAMYKAKATDGNYRVYSSHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ83</accession>
    <name>B1KQ83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323087.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0440"/>
    <dbReference type="EnsemblBacteria" id="ACA84738">
        <property type="protein sequence ID" value="ACA84738"/>
        <property type="gene ID" value="Swoo_0440"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0440"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_6"/>
    <dbReference type="OMA" id="FERDNRS"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08430">
        <property type="entry name" value="PBP2_IlvY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037404">
        <property type="entry name" value="IlvY_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="32388" checksum="8EC71CC993746CD6" modified="2008-04-29" version="1">MDIKTIKLYLHLSESLHFSRTAQAMHVSPSTLSRAMQRLEDEVGAKLFQRDNRSVSLTSAGVEYRHFAEQTLDHWSKLKTKIDPKQDLLRGRLNLYCSVTAAYSHLPGLLDSFRREHPLVEIALTTGDAANAVNEVKNNRADVAIAALPDPFPDSLHFVKIDDVPLVIIAPTYRCQVQELLSESYIPWDRLPFIVPEHGPGRRRVDNWFKQLGLSPNIYAQVSGQEAIASMVALGCGVSITPDVVINNSPVRDRIQIIPSPIEIPPFELGCCCKTKSQKDPIISAFLKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB6</accession>
    <name>B1KQB6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA/MotB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323120.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0473"/>
    <dbReference type="EnsemblBacteria" id="ACA84771">
        <property type="protein sequence ID" value="ACA84771"/>
        <property type="gene ID" value="Swoo_0473"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0473"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016890_7_0_6"/>
    <dbReference type="OMA" id="GHCSKTG"/>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767559" evidence="3">
        <location>
            <begin position="23"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="71"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="22612" checksum="4B472725B60566B4" modified="2008-04-29" version="1" precursor="true">MRTFILILSVTLLAGCSMRDIATMDGATTQVHDLNDNDRDGVIVARERCTETVGGATIDNYGCGKIKPINERQELKILFPNDSYYIDPMYYDQVEIIATFMRQFPNTKVTIEGHCSKTGSYEHNLALSQNRANAVTTALSERFGIEPDRLTAIGYSFDRPIDLSETAMAHTRNRRVIAEVTGEDTTADMKWNIYTVDEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH4</accession>
    <name>B1KQH4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione hydrolase proenzyme</fullName>
            <ecNumber evidence="4">2.3.2.2</ecNumber>
            <ecNumber evidence="4">3.4.19.13</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase large chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase small chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1929</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Cleaved by autocatalysis into a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="4"/>
    <dbReference type="EC" id="3.4.19.13" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324559.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1929"/>
    <dbReference type="MEROPS" id="T03.001"/>
    <dbReference type="EnsemblBacteria" id="ACA86213">
        <property type="protein sequence ID" value="ACA86213"/>
        <property type="gene ID" value="Swoo_1929"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1929"/>
    <dbReference type="eggNOG" id="COG0405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014813_0_3_6"/>
    <dbReference type="OMA" id="KATKNMF"/>
    <dbReference type="OrthoDB" id="595845at2"/>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00462">
        <property type="entry name" value="G_GLU_TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767297" description="Glutathione hydrolase proenzyme" evidence="5">
        <location>
            <begin position="31"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="581" mass="62296" checksum="02F10D2D6A57C89C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQK7</accession>
    <name>B1KQK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MCP methyltransferase, CheR-type</fullName>
            <ecNumber evidence="2">2.1.1.80</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.80" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1962"/>
    <dbReference type="EnsemblBacteria" id="ACA86246">
        <property type="protein sequence ID" value="ACA86246"/>
        <property type="gene ID" value="Swoo_1962"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1962"/>
    <dbReference type="eggNOG" id="COG1352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025854_1_0_6"/>
    <dbReference type="OMA" id="DYYTAAY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="32950" checksum="751A5469BB03E1F3" modified="2008-04-29" version="1">MLGMKLEDMQEFEIDLLLEAIYFRYGYDFRDYSKASLERRVLHRVQQSNLNSISEMVPRVMHDTEFFELFLRDMSVTVTEMFRDPKVFHKLRQEVFTQLKTYSRVNIWHAGCATGEEVYSMAIMLKEEGLLDRTRIYATDYNNHSLDIAKKGIYPVEKMKLYTESYIAAGGKASFADYYLAKFGSVKMAESLKEHITFANHNLMKDQPFAEMHLIVCRNVLIYFNAKLQDRVLTLFKDSLIARGFLLLGDKETLDFSEVKSYFETFNKKERIYRRLMHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQS1</accession>
    <name>B1KQS1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326012.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87677">
        <property type="protein sequence ID" value="ACA87677"/>
        <property type="gene ID" value="Swoo_3409"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3409"/>
    <dbReference type="eggNOG" id="ENOG5032BY2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128701_0_0_6"/>
    <dbReference type="OMA" id="IEAYVIF"/>
    <dbReference type="OrthoDB" id="2061440at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="17112" checksum="2179283A540F4CA1" modified="2008-04-29" version="1">MHTEITRLSKRLRRVFEKQAIRTELPHLCHFPKNSCQLASLYLGVLINRQFPTVYIELIHGRHRLKEENHYWLEVNGFSYDITADQFDDINEPIYAGLSNPLSTYFSPYHSTEVMQAFSDYQQVEGERSLSILAQIEVLLNQASPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQV5</accession>
    <name>B1KQV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87711">
        <property type="protein sequence ID" value="ACA87711"/>
        <property type="gene ID" value="Swoo_3443"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3443"/>
    <dbReference type="HOGENOM" id="CLU_3011829_0_0_6"/>
    <dbReference type="OMA" id="NSQPEHY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="56" mass="6801" checksum="22401FA075D78E22" modified="2008-04-29" version="1">MSNFYDNDDLLWDSEIGEETRDKHKSKRNKHNRRQLSDQKRQAFESEQASRSTYHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRA9</accession>
    <name>B1KRA9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease E</fullName>
            <shortName evidence="6">RNase E</shortName>
            <ecNumber evidence="6">3.1.26.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rne</name>
        <name evidence="9" type="ordered locus">Swoo_2032</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions.</text>
            <dbReference type="EC" id="3.1.26.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per homotetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RNase E/G family. RNase E subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.12" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324662.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2032"/>
    <dbReference type="EnsemblBacteria" id="ACA86316">
        <property type="protein sequence ID" value="ACA86316"/>
        <property type="gene ID" value="Swoo_2032"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2032"/>
    <dbReference type="eggNOG" id="COG1530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003468_1_3_6"/>
    <dbReference type="OMA" id="YEELEWD"/>
    <dbReference type="OrthoDB" id="1209444at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008995">
        <property type="term" value="F:ribonuclease E activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00970">
        <property type="entry name" value="RNase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028878">
        <property type="entry name" value="RNase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="39"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Required for zinc-mediated homotetramerization and catalytic activity" evidence="6">
        <location>
            <begin position="403"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="478"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="569"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1110"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="481"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="596"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="646"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="689"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="707"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="729"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="770"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="810"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1113"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1142" mass="125281" checksum="0711666F5B42AD6B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD3</accession>
    <name>B1KRD3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CvfB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324685.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2056"/>
    <dbReference type="EnsemblBacteria" id="ACA86340">
        <property type="protein sequence ID" value="ACA86340"/>
        <property type="gene ID" value="Swoo_2056"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2056"/>
    <dbReference type="eggNOG" id="COG2996">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064885_1_0_6"/>
    <dbReference type="OMA" id="GAFMDWG"/>
    <dbReference type="OrthoDB" id="1382881at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014464">
        <property type="entry name" value="CvfB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039566">
        <property type="entry name" value="CvfB_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040764">
        <property type="entry name" value="CvfB_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37296">
        <property type="entry name" value="PTHR37296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17783">
        <property type="entry name" value="CvfB_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13509">
        <property type="entry name" value="S1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012524">
        <property type="entry name" value="YitL_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1_2" evidence="2">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="S1_2" evidence="2">
        <location>
            <begin position="71"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="CvfB_WH" evidence="3">
        <location>
            <begin position="219"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR012524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="31308" checksum="92673DE5363F2CD6" modified="2008-04-29" version="1">MIQIGKTSRLEVVKTVEFGVYLDGQELGQILLPTKFMPKECNLGDLVEVFIYLDSEDKLIATTRKPIAQVGEFAYLKAVATGPYGAFLDWGLEKDLLLPFGEQHREIEEGRSYLVYIYTNSADERIVASSKIDKFLDKTPPPYDTGEEVNLIIGGTTDLGYKAIINHSHWGVIFKNEVFRSLSFGQRVKGFIKQVRGDDKIDLILQKGVKEELDKHSTTIMFKLKQAGGYLPLNDKTDADTIYAKLSMSKKAFKKSIGGLYKAKQITISPDGIRLVDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRI2</accession>
    <name>B1KRI2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA threonylcarbamoyladenosine biosynthesis protein TsaB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KAE1 / TsaD family. TsaB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324734.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2105"/>
    <dbReference type="EnsemblBacteria" id="ACA86389">
        <property type="protein sequence ID" value="ACA86389"/>
        <property type="gene ID" value="Swoo_2105"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2105"/>
    <dbReference type="eggNOG" id="COG1214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064886_2_0_6"/>
    <dbReference type="OMA" id="DEVYWGC"/>
    <dbReference type="OrthoDB" id="1826274at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TsaD" evidence="4">
        <location>
            <begin position="40"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="25693" checksum="6DAE386480ADB573" modified="2008-04-29" version="1">MTEIQKNPDELTILSLDTCTESCSAALSVKGKVFSELAIVPREHSQRILPMVDSVLSQAKVQLADVDLIAYGRGPGSFTGIRICTSMTQGLALGQDIPVIGLSALQTMAQAVFDSQSAMQVITAIDARMGEIYWGQFVFDNGLVKLVGAETVIAPDLVTLELNTELPIVACGTGFETYPQLLELTGSITLAKEVTFPDAKSMLSLAKQGYTQGLATSVDYLAPVYVRDTVTWKKLPGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRQ0</accession>
    <name>B1KRQ0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3551</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326148.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3551"/>
    <dbReference type="EnsemblBacteria" id="ACA87815">
        <property type="protein sequence ID" value="ACA87815"/>
        <property type="gene ID" value="Swoo_3551"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3551"/>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016813_4_2_6"/>
    <dbReference type="OMA" id="IVWHTVI"/>
    <dbReference type="OrthoDB" id="437016at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018270">
        <property type="entry name" value="C_nuclsd_transpt_met_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00804">
        <property type="entry name" value="nupC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="7">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="9">
        <location>
            <begin position="92"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="8">
        <location>
            <begin position="194"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="419" mass="43526" checksum="B8708499BADAA1DC" modified="2008-04-29" version="1" precursor="true">MDILMSLVGVVTLLAIAFALSNNKKAINKRTVFGALAIQAAFGGFVLYVPVGKDILKTVSDGVSSVIGYAQNGIGFLFGDLANFKVGFIFAVNVLPVIVFFSSLIAVLYYLGVMQWIIRIIGGALQKALGTSRTESMSATANIFVGQTEAPLVVRPFIATMTNSELFAIMVGGLASIAGSVMAGYAQMGVPIEYLVAASFMAAPGGLLMAKLMHPETEEAKNDMSDLPEDPDKPANVLDAAAAGASSGMHLALNVGAMLLAFVGLIAMLNGIIGGIGGFIGMEGLTLELILGYIFMPLAFLIGVPWNEALVAGSFIGQKIVVNEFVAYLNFAPYLKDVADGGVLVEATQAVMTDRTKAIISFALCGFANLSSIAILLGGLGAMAPTRRHDLAKLGIRAVIAGSLANLMSATLAGLFLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCV5</accession>
    <name>B1KCV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322679.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84330">
        <property type="protein sequence ID" value="ACA84330"/>
        <property type="gene ID" value="Swoo_0029"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0029"/>
    <dbReference type="eggNOG" id="ENOG5032QFG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137966_0_0_6"/>
    <dbReference type="OMA" id="MHIEAKL"/>
    <dbReference type="OrthoDB" id="1850029at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="16972" checksum="CDD49AE453DDEC77" modified="2008-04-29" version="1">MRSLFQTASIIFPVIILPIKTHATVIELNTYLGGSEGKLANKPALIYKFSDGSQQNRCSIITTENYLVNAKNRLENINLSEPNFYFDCVWDGRYYFLSNRHRTYAEVIIKQPDMNFPMSMHIEAKLINIIGEHAEVISGDISLRRSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCW6</accession>
    <name>B1KCW6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0040"/>
    <dbReference type="EnsemblBacteria" id="ACA84341">
        <property type="protein sequence ID" value="ACA84341"/>
        <property type="gene ID" value="Swoo_0040"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0040"/>
    <dbReference type="eggNOG" id="COG0758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029601_1_1_6"/>
    <dbReference type="OMA" id="SEMPFGW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="273"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="331" mass="35482" checksum="300460BF3BA3F206" modified="2008-04-29" version="1">MLAHEKSALPLPESLLERELAPNLNLVESALAWQESADNHAIICFDDPHYPSFLKQISAPPPILFVKGELDAFFPPALAIVGSRAASKAGLQLAYRFGSELGELGFGVCSGMAVGVDGSAHQGCLDSGGKTLAVLGTGVDVIYPKRHRKIYEDIQAHGAIVSEFWPGTKPFSGNFPKRNRIISGLSIGTLVVEACRKSGSLITARLALEQGREVFAIPGSVLAENNQGCHDLIKDGAKLVENVADIIEEVSALCDFHLEELKSSHHIGEENASDLPFASLLASVGYETTPIDVVVEHSGKAIELVLEQMLELELQGWVAVVPGGYVRIKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD82</accession>
    <name>B1KD82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326250.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3655"/>
    <dbReference type="EnsemblBacteria" id="ACA87917">
        <property type="protein sequence ID" value="ACA87917"/>
        <property type="gene ID" value="Swoo_3655"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3655"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_9_1_6"/>
    <dbReference type="OMA" id="DHGELHG"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767257" evidence="2">
        <location>
            <begin position="22"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="526" mass="59680" checksum="04B9487F613437F9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD99</accession>
    <name>B1KD99_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326267.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3672"/>
    <dbReference type="EnsemblBacteria" id="ACA87934">
        <property type="protein sequence ID" value="ACA87934"/>
        <property type="gene ID" value="Swoo_3672"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3672"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069810_0_0_6"/>
    <dbReference type="OMA" id="HRAAWVL"/>
    <dbReference type="OrthoDB" id="1503557at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="31702" checksum="7581B552B59E29B2" modified="2008-04-29" version="1">MWIFFTLLAAFMQAWRNAFQSQLSKEVSVAGVTLARFIWAWPIAGGYLIGLYLWQSVALPVFTVEFVLYIIGASVMQILATALLVKLFKLKNFAVGAGLAKSEALVAAVLGLCIFGTQLSVLGWIGVSIGGVAVFMMSSRQGLRDISLSTALIGLTCGSAFALTSLWVREASLSLSLPFPHRAAWVLLLVISLQTLILLGYIIVKERATLAGLWQRPRQTILISSTSCLGSVGWFSAMSLQAVPYVKTLGQVEVFFTLFIAMFWLKERVKIKDMLALILIALAAILVMWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF4</accession>
    <name>B1KDF4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0659</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323302.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0659"/>
    <dbReference type="EnsemblBacteria" id="ACA84955">
        <property type="protein sequence ID" value="ACA84955"/>
        <property type="gene ID" value="Swoo_0659"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0659"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_42_3_6"/>
    <dbReference type="OMA" id="NACKWAD"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="181"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="241"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="441" mass="49200" checksum="D77C259309832E1A" modified="2008-04-29" version="1" precursor="true">MISIKTKLSLWLTGLVILSTAVGIVFFESMLRQAFHDSIIARLQEDIEQVMLATHLNDEQFSIDQSQLSGFYKPVFSGRYYQLNLADLEIRSRSLWDQRLNIEMLPLGETRVWQAKGPLNHDIQLLSIGLKSESTGLDATLTVAQDLSIGRKVFTQIYGTKLGVNLAMLLTMIMGIFLVIRQSFKPVNQIQDVLARLREGEITSIEVSKIPSELRPLAATYNDLLDYSGKQIERSRNNLGNLSHGLKTPLAVMQQQVEALGLKDPDSAIALQSQLDLVHKMIERKLAAARITGDMLPAAQMQIPKDIEDLSKTLSKVHFNKQIICSFDIPDTISRLPIHREDGMELIGNLLDNAHKWAKERVEVSVTNEASGISLVIEDDGPGVADDELCLLTNRGKRLDEATMGHGLGLSIVKDIAEQYEIKLAFTKSMKLGGLRIKLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL5</accession>
    <name>B1KDL5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paraquat-inducible protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324757.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2128"/>
    <dbReference type="EnsemblBacteria" id="ACA86412">
        <property type="protein sequence ID" value="ACA86412"/>
        <property type="gene ID" value="Swoo_2128"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2128"/>
    <dbReference type="eggNOG" id="COG2995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041903_2_0_6"/>
    <dbReference type="OMA" id="VQKSWAL"/>
    <dbReference type="OrthoDB" id="836803at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007498">
        <property type="entry name" value="PqiA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04403">
        <property type="entry name" value="PqiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="216" mass="24140" checksum="13310561052C1A3C" modified="2008-04-29" version="1" precursor="true">MSNIDENAQGKEMGLTTCPSCNKLNEQKQTHCTRCDSPLMVRDTTSLQKSWALLITAAILLIPANIYPITMLTDRGRIRHDTIFTGITHLVQSDMFPIAIILFTASILVPLLKIVGLTIYLTAISFRLPISKKMLMVGFHIIEWIGRWSMLDLFVISITVALVNMGQLLDAKPAPAATAFALVILLTQMAAKVLDTRLLWDRLESKDDKNRSTKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDR8</accession>
    <name>B1KDR8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-containing alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324809.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2183"/>
    <dbReference type="EnsemblBacteria" id="ACA86465">
        <property type="protein sequence ID" value="ACA86465"/>
        <property type="gene ID" value="Swoo_2183"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2183"/>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_773153_0_0_6"/>
    <dbReference type="OMA" id="MMASYMG"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="11"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="356" mass="39385" checksum="262D41CF9A7876A2" modified="2008-04-29" version="1">MSFKNFKCVPKMIFGRGSFAQLDAVLAEERQSDDDFVVFLVDDVHQSKPLAERVPAKAHDLLIYVNVDDEPTTKQVDALTEQVQAFNSKQPVSVIGLGGGSTLDLAKAVSLMLTNPGGSAMYQGWDLIKNPAIHHIGIPTVSGTGAEASRTAVLCGPVRKLGLNSDYTVFDQIIMDSELIAGVPTDQWFYTGMDCYIHCVESLEGTYLNEFAKAFAEKSMDLCREVFIDDHAEKDDKLMMASYMGGMSIAYSQVGACHAVSYGLGYVLGYHHGIGNCLAFDVLEEFYPEGVAEFRQMMDKHNIKLPKNICKDLPDETIAKMVAVTKSMGPLWDNVYGEGWEEKVTDEMLTKLFRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE64</accession>
    <name>B1KE64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323397.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0755"/>
    <dbReference type="EnsemblBacteria" id="ACA85050">
        <property type="protein sequence ID" value="ACA85050"/>
        <property type="gene ID" value="Swoo_0755"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0755"/>
    <dbReference type="eggNOG" id="ENOG50331VM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168123_0_0_6"/>
    <dbReference type="OMA" id="TKNMGTY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="9615" checksum="8FF179BA447518C3" modified="2008-04-29" version="1">MTKFKSLGQGMTEYIIIVALIAVSAIGVYSFFGQTVRNQVSGLSSEVSGQDSQGQITAAQQSSASATGVADQDYNLGNYNEGANGASGGGGGTGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEB0</accession>
    <name>B1KEB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324832.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2206"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86488">
        <property type="protein sequence ID" value="ACA86488"/>
        <property type="gene ID" value="Swoo_2206"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2206"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023351_0_0_6"/>
    <dbReference type="OMA" id="HIWYTGV"/>
    <dbReference type="OrthoDB" id="1573900at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="68"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="668" mass="74388" checksum="0C4D93C5FEA50A31" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEL0</accession>
    <name>B1KEL0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326357.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3766"/>
    <dbReference type="EnsemblBacteria" id="ACA88025">
        <property type="protein sequence ID" value="ACA88025"/>
        <property type="gene ID" value="Swoo_3766"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3766"/>
    <dbReference type="eggNOG" id="ENOG5033HYJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1577436_0_0_6"/>
    <dbReference type="OMA" id="CTADKAT"/>
    <dbReference type="OrthoDB" id="2220852at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="18822" checksum="DDCFC6E28B9EFD2A" modified="2008-04-29" version="1" precursor="true">MKKAMLSTLLVLSTACSTDKIDKTETPSAMPVETSTSTVITKDETVNKKKLLITEQDKKTQDKTYSYRLNDQKFTSNAKVLVKGSSVSSPIMSESGVLKGSFVVITTAKTESLSTHYKVNKIAKNTYRLIPIKNQTDLYNLYSNLLKNSELSRVEIEVDYSRASTAQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEM4</accession>
    <name>B1KEM4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative aliphatic amidase expression-regulating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326370.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3780"/>
    <dbReference type="EnsemblBacteria" id="ACA88039">
        <property type="protein sequence ID" value="ACA88039"/>
        <property type="gene ID" value="Swoo_3780"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3780"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_1_6"/>
    <dbReference type="OMA" id="HTVLNEG"/>
    <dbReference type="OrthoDB" id="538961at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06355">
        <property type="entry name" value="PBP1_FmdD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017777">
        <property type="entry name" value="ABC_urea-bd_UrtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="45396" checksum="586C9171F9667620" modified="2008-04-29" version="1" precursor="true">MLKKIRLSFYICLFIIGLLVALQACNREQNTKVKIGVLHSITGTMSFSERDLVDVISLAVKEINRDGGLLGKKIEPVLADGASDWNIFAAKAEKLITTDKVAVIFGCWTSSCRKSVKPVIEEHHHLMFYPLQYEGLELSPNIIYTGATPNQQIIPSVHWALENIGERVYLIGSDYIFPRAANMIIKDQLKSRGITPLGETYIPLGSNDLTEALREIGELKPDVVVNTINGDSNIAFFRGISTLSKVKVLSYSIGEPEVRAIGEELMVGHFAAWNYFQSIESDENKRFIDAFKREFGAERVVNDPMEATYIGVKLWAQAVKSAASFEPLRIRSTLAHQSLNAPHGVVSVEALSQHLWKTVRIGQVRDDGQFDIVWSSDSPIRPSPFPTYHKKQEWLKRLRELELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEP5</accession>
    <name>B1KEP5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_3801</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPPK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326391.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3801"/>
    <dbReference type="EnsemblBacteria" id="ACA88060">
        <property type="protein sequence ID" value="ACA88060"/>
        <property type="gene ID" value="Swoo_3801"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3801"/>
    <dbReference type="eggNOG" id="COG0801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097916_2_3_6"/>
    <dbReference type="OMA" id="QVILRQN"/>
    <dbReference type="OrthoDB" id="1953248at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="13">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA88060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="166" mass="18408" checksum="1B485BC27AF1050E" modified="2008-04-29" version="1">MAKVFVALGANLTDPVAQLDSASMALSELAEVNPTNGLTSLTLSPYYRSAPMGEVEQPDYVNAVACFDTSLSPIDLLDALQKIENEQERVRLERWGPRTLDLDILLYDDQIIDSPRLTIPHYGMKQRSFVLIPLEDIAPNTILPCGTELKGLIDAKLRAQLEQIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER1</accession>
    <name>B1KER1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326407.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3817"/>
    <dbReference type="EnsemblBacteria" id="ACA88076">
        <property type="protein sequence ID" value="ACA88076"/>
        <property type="gene ID" value="Swoo_3817"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3817"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="CEGYRRP"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="36257" checksum="5313EEE09091F3FF" modified="2008-04-29" version="1">MSNREYALVIDSLKKTYKGGVEAVKGVSLKVNRGDFFALLGPNGAGKSTTIGVISSLVQKTSGKVCVFEHDIDSELELAKLCIGLVPQEFNFNQFEKVLQIVVNQAGYYGVSRSVAMERAEKYLTQLDLWEKRNTPARELSGGMKRRLMIARALMHEPKLLILDEPTAGVDIELRRSMWTFLTELNKQGVTIILTTHYLEEAEMLCRNIGIIDKGVLVECTSMKSLLSRLNLETFILDLGTDLTQEPKFEGFNSRLTDEHTLEVDVAKEQSINSVFSQLSEQGIEVLSMRNKANRLEELFVELVERGSLGAESTKSKAISTQGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER3</accession>
    <name>B1KER3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin prenyltransferase UbiX</fullName>
            <ecNumber evidence="5">2.5.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiX</name>
        <name evidence="7" type="ordered locus">Swoo_3819</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2</text>
            <dbReference type="Rhea" id="RHEA:37743"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:87467"/>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
            <dbReference type="EC" id="2.5.1.129"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UbiX/PAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.129" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326409.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3819"/>
    <dbReference type="EnsemblBacteria" id="ACA88078">
        <property type="protein sequence ID" value="ACA88078"/>
        <property type="gene ID" value="Swoo_3819"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3819"/>
    <dbReference type="eggNOG" id="COG0163">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074522_0_0_6"/>
    <dbReference type="OMA" id="FERWNGW"/>
    <dbReference type="OrthoDB" id="1384786at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106141">
        <property type="term" value="F:flavin prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01984">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="PTHR43374"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00421">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavoprotein" evidence="6">
        <location>
            <begin position="8"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="16"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="111"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="23897" checksum="3B826665F62A20E7" modified="2008-04-29" version="1">MNYPRKTKSISLAWTGASGAPYGLKLLECLLVADYQVFLMISSAARVVLATEQGVKLSANSDKAKEQILSYFANLGVEFTGELHLLGKDEWFSPPASGSAAPKQMVICPCSTGTLASVATGMSNSLLERAADVVIKERGQLLLVPRETPFSSIHLEHMLSLSRLGVTIMPASPGFYHDPKSIQDLVNFMVARILDHLGVEHELTNRWGYEQNSSSDRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW8</accession>
    <name>B1KEW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DGPFAETKE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323466.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0824"/>
    <dbReference type="EnsemblBacteria" id="ACA85119">
        <property type="protein sequence ID" value="ACA85119"/>
        <property type="gene ID" value="Swoo_0824"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0824"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_2_1_6"/>
    <dbReference type="OMA" id="QYALIIR"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12998" checksum="2556F1753BBF27BD" modified="2008-04-29" version="1">MKFLALIYSQPNSEPEYNTPEWDEMLKDYMAITEEFKRDGVFIAGEGLQDVSTATSVKVRVNQAELHDGPFAETKEQLGGFYLLDCKDLDQALQYAAKIPSAKWGTVEVRPVAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFA7</accession>
    <name>B1KFA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein with EFhand domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324990.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2369"/>
    <dbReference type="EnsemblBacteria" id="ACA86648">
        <property type="protein sequence ID" value="ACA86648"/>
        <property type="gene ID" value="Swoo_2369"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2369"/>
    <dbReference type="eggNOG" id="COG5126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_22_5_6"/>
    <dbReference type="OMA" id="HSTHIEF"/>
    <dbReference type="OrthoDB" id="1809211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="4"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="73" mass="8243" checksum="C2D2069CEF3C0C69" modified="2008-04-29" version="1">MTQISIEELQDNFTHFDTDSDGTIELSEFNRLLVALDALAPGESDPIGFDAIDTDGNGRIDFKEFSDWFNNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFB0</accession>
    <name>B1KFB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324993.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2372"/>
    <dbReference type="EnsemblBacteria" id="ACA86651">
        <property type="protein sequence ID" value="ACA86651"/>
        <property type="gene ID" value="Swoo_2372"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2372"/>
    <dbReference type="eggNOG" id="COG4628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111109_0_0_6"/>
    <dbReference type="OMA" id="ECFNINP"/>
    <dbReference type="OrthoDB" id="1457473at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018668">
        <property type="entry name" value="DNA-binding_VF530-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09905">
        <property type="entry name" value="VF530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="18768" checksum="1A4CF7A4FD711B03" modified="2008-04-29" version="1">MIEEQKNNPLHGLKLEVMLTELVDFYDWKILYAALRLECFNINPSHEACLKFLKKTEWARERVESFYLYRFKRMPKGSSAQFELKPRERGFADGIVPRKPETLTIELIEQMRAKATADYEAMKANKSKGYGKKVYDGAYKTRTNDNRPKPSQDPKNPWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFG4</accession>
    <name>B1KFG4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Catalase</fullName>
            <ecNumber evidence="4 14">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Swoo_3881</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="4 14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326469.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3881"/>
    <dbReference type="EnsemblBacteria" id="ACA88139">
        <property type="protein sequence ID" value="ACA88139"/>
        <property type="gene ID" value="Swoo_3881"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3881"/>
    <dbReference type="eggNOG" id="COG0753">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_2_0_6"/>
    <dbReference type="OMA" id="WTCYVQV"/>
    <dbReference type="OrthoDB" id="1584770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="PTHR11465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 14 17" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="16">
        <location>
            <begin position="6"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA88139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="480" mass="54340" checksum="C73828D6FC5E265F" modified="2008-04-29" version="1">MDKKLTTAFGAPVPDNQNVKTAGKRGPMLLENAWFIEKLAHFDREVIPERRMHAKGSGAFGRFTVTHDISEFTKAKLFESVGKETEVFVRFSTVAGERGAADAERDIRGFAIKFYTEQGNWDLVGNNTPVFFLKDPLKFPDLNHAVKRDPYTNMRSANNNWDFWTLSPEALHQITMTMGDRGIPKTYRHMDGFGSHTYSFISKDDKRYWVKFHFKTQQGIQNLSDKEAAEIIANDRESHQADLLNSIDKGDFPKWTLYVQLMEETAAGDCPFNPFDLTKVWPHKDYPLIQVGELELNRNPDNYFAEVEQAAFAPTTIVPGIGFSPDKMLQGRLFSYGDSQRYRLGVNHSHIPVNAPKCPFHSYHRDGQMRTDGNAGRTIGYEPNTQSQWQEQPDFSEPPLQIDGDADAYSHKDDDHYSQAGDLFRLMGSDEQQRLFANTAASVGGADRHIQIRHIQNCMKADVAYGEGLAKVLGISADEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI5</accession>
    <name>B1KFI5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptide chain release factor H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326490.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3902"/>
    <dbReference type="EnsemblBacteria" id="ACA88160">
        <property type="protein sequence ID" value="ACA88160"/>
        <property type="gene ID" value="Swoo_3902"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3902"/>
    <dbReference type="eggNOG" id="COG1186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036856_4_0_6"/>
    <dbReference type="OMA" id="HKRKNWF"/>
    <dbReference type="OrthoDB" id="1381946at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017509">
        <property type="entry name" value="Release_fac_PrfH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03072">
        <property type="entry name" value="release_prfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="2">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="218" mass="24764" checksum="6151BC0949906245" modified="2008-04-29" version="1">MILLQLSAGQGPAACCKAIGLALKEIEKQCREKGVAFDLIEAIETKERFCFKSVLLQLESKQSVLGEDDLAKQLAKSWQGAMLWICQSPFQLEKNRVKNKRKNWFFSGQMYEFNETELDKEVSFQTCRASGAGGQHVNTTDSAVRAIHVATGISVRVESERSQHANKRLARALLFQKLESTKVEQMSLQEKARWQQHWEVERGNPVKTFKGEKFTLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI6</accession>
    <name>B1KFI6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Release factor H-coupled RctB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326491.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3903"/>
    <dbReference type="EnsemblBacteria" id="ACA88161">
        <property type="protein sequence ID" value="ACA88161"/>
        <property type="gene ID" value="Swoo_3903"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3903"/>
    <dbReference type="eggNOG" id="COG1690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022279_3_0_6"/>
    <dbReference type="OMA" id="TRGECCR"/>
    <dbReference type="OrthoDB" id="1384936at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017510">
        <property type="entry name" value="Release_fac_RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="PTHR11118"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03073">
        <property type="entry name" value="release_rtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="307"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="43181" checksum="75A4580481A06BD3" modified="2008-04-29" version="1">MGKSVQKITENVSLIASADTWIEGLAIQQLIKTSELSGMHRVAGMPDLHPGRGYPIGAAFFTTNRVYPALVGNDIGCGMSFWQTSAKVSKVSLDKFAKKFEHVEESLDDSWSETIASRKCAKGITTDSYDRALGTIGGGNHFAEFQAIDEVYDQAALEYLGLNKRQLQLLVHSGSRGLGQSILVEHISKHNHNGLLVEGADVGDSFQDYIRKHDEAVRWAELNRELIALRFLDSIRAKGDCVLDINHNLVSAQNIDGREGWLHRKGATPSDKGYVVIPGSRGDYSYLVKPLCSNGDALKVSLFSLAHGAGRKWKRGECHGRLGHKYKREDLYRTALGSRVVCGNKELLYDEAPQAYKKCETVIKDMVDAGLIELVAKLRPVLTFKTNGDCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFJ2</accession>
    <name>B1KFJ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Endothelin-converting enzyme 1</fullName>
            <ecNumber evidence="11">3.4.24.71</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3909</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.71" evidence="11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326497.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3909"/>
    <dbReference type="EnsemblBacteria" id="ACA88167">
        <property type="protein sequence ID" value="ACA88167"/>
        <property type="gene ID" value="Swoo_3909"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3909"/>
    <dbReference type="eggNOG" id="COG3590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006187_7_2_6"/>
    <dbReference type="OMA" id="APRNHDA"/>
    <dbReference type="OrthoDB" id="305005at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766537" evidence="8">
        <location>
            <begin position="20"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="58"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="487"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="690" mass="77228" checksum="A0EB72528435D695" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ6</accession>
    <name>B1KFQ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alkyl hydroperoxide reductase subunit F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_0929</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323569.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0929"/>
    <dbReference type="EnsemblBacteria" id="ACA85222">
        <property type="protein sequence ID" value="ACA85222"/>
        <property type="gene ID" value="Swoo_0929"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0929"/>
    <dbReference type="eggNOG" id="COG3634">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_4_0_6"/>
    <dbReference type="OMA" id="LVPNAEW"/>
    <dbReference type="OrthoDB" id="692968at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008785">
        <property type="term" value="F:alkyl hydroperoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03026">
        <property type="entry name" value="AhpF_NTD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02974">
        <property type="entry name" value="AhpF_NTD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044141">
        <property type="entry name" value="AhpF_NTD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044142">
        <property type="entry name" value="AhpF_NTD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012081">
        <property type="entry name" value="Alkyl_hydroperoxide_Rdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13192">
        <property type="entry name" value="Thioredoxin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000238">
        <property type="entry name" value="AhpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03140">
        <property type="entry name" value="AhpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="13">
        <location>
            <begin position="123"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="12">
        <location>
            <begin position="211"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="339"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000238-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000238-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="522" mass="55904" checksum="69F5A2B99094848C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT6</accession>
    <name>B1KFT6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323599.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0959"/>
    <dbReference type="EnsemblBacteria" id="ACA85252">
        <property type="protein sequence ID" value="ACA85252"/>
        <property type="gene ID" value="Swoo_0959"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0959"/>
    <dbReference type="eggNOG" id="COG3540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015982_1_0_6"/>
    <dbReference type="OMA" id="SCANWEA"/>
    <dbReference type="OrthoDB" id="165142at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032093">
        <property type="entry name" value="PhoD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16655">
        <property type="entry name" value="PhoD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD_N" evidence="2">
        <location>
            <begin position="47"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD" evidence="1">
        <location>
            <begin position="146"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="589" mass="64621" checksum="DA1F396B7BE5EFE1" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFX0</accession>
    <name>B1KFX0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325019.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2399"/>
    <dbReference type="EnsemblBacteria" id="ACA86677">
        <property type="protein sequence ID" value="ACA86677"/>
        <property type="gene ID" value="Swoo_2399"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2399"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070319_2_0_6"/>
    <dbReference type="OMA" id="YEKAAQP"/>
    <dbReference type="OrthoDB" id="1152952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="70"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="277" mass="30102" checksum="1A2C22335B1D6AC0" modified="2008-04-29" version="1">MKKHWPKYLLIGLPVFILVIYLGLPKFLTLLGLHPHYDIPAYDLPGKRALIVTTSHGTLGDTGKATGVFGSEMTVPYYAFQDTGMDVDIASIKGGEIPVEPRSMGWPLATEDDLRFKEDSVAMAKMTNSIPIKDIDPAKYDVIFMAGGWGAAYDFAQSEALASIITKANTNDTLLGAICHGVLGLVNAKDKDGSSLIEGRRATGVTDLQIKQLGIDITPKHPETELRKAGAIYEANTAFRDMMATHVVVDGNIITGQNQNSGYETAHRILEKLAQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG03</accession>
    <name>B1KG03_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325052.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2432"/>
    <dbReference type="EnsemblBacteria" id="ACA86710">
        <property type="protein sequence ID" value="ACA86710"/>
        <property type="gene ID" value="Swoo_2432"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2432"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071599_0_0_6"/>
    <dbReference type="OMA" id="GGFWNAY"/>
    <dbReference type="OrthoDB" id="1264438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="274" mass="30666" checksum="FEE52DFE506F78F8" modified="2008-04-29" version="1">MEPFEHAREALADAEVVFIGAGAGLSASAGLDYTDQKAFAERFPGMLQYGFRFQYQLMGYPFDDEALKWGYLATGLNHVYHSQQTQVYQDLLSLVDERDSFVITSNVDRYFHKNGFDTANIYTPQGDYERFQCMTPCTDLVWDGRESVASMLPYINPETQYVENRSTLPVCPNCGGPVFMNVRGGSWFIEKPYETQADAISNWLNDNLNRKMAIVEIGAGFNTPGVIRLPLENIAKQLPDARLIRISKEHADGPVGTISLQMTADEALSKMISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG05</accession>
    <name>B1KG05_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325054.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2434"/>
    <dbReference type="EnsemblBacteria" id="ACA86712">
        <property type="protein sequence ID" value="ACA86712"/>
        <property type="gene ID" value="Swoo_2434"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2434"/>
    <dbReference type="eggNOG" id="COG4922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073327_1_0_6"/>
    <dbReference type="OMA" id="YIQHNLA"/>
    <dbReference type="OrthoDB" id="1598464at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="PTHR38436"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766562" evidence="1">
        <location>
            <begin position="21"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="166"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="276" mass="29363" checksum="C4B8B55A7D17C3FE" modified="2008-04-29" version="1" precursor="true">MKKSIIAAASAVIASAAVLADTPKGVAVAEMASLFKDFDKVQAAATMAPDLIQHNQAVPNGAAVLIDLIPTLKESGISATTHRLISEGNMVVAHNEYKNAKVFGGDHLAAFDVFRIEDGKVAEHWDNLTPVTAPNPSGRTQFDGTTVVTDLDKTAENKAVVTSFVYDVLHGKAPDKITDYVSTETYLQHNSGVADGLDGLGEAIKAMADAGLSMTYSDTHMIIAEGNFVFTASEGEFSGDHVAFYDLFRVDGGKIVEHWDVIQTISEKSANDSGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG11</accession>
    <name>B1KG11_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325060.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2440"/>
    <dbReference type="EnsemblBacteria" id="ACA86718">
        <property type="protein sequence ID" value="ACA86718"/>
        <property type="gene ID" value="Swoo_2440"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2440"/>
    <dbReference type="HOGENOM" id="CLU_952817_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="32387" checksum="03F919535377AC6C" modified="2008-04-29" version="1">MSISQISANMFDADRTVKIRTFCSSDDNSRKTLPGSLQYIHLYSSKARAEFAAANSNVSDGFDHGFVYIESPGNAYVKWRNIAGEIQFCGSGAYALAWHMLKAETVTQVSLHTTHRTLIADSSGDSAAISTNPSIEEPNTASCYLSIPSFHPVEVTHFSTKAIIDGLEEAGHLYVDCTSGIYLLQLNDTETLADTTWLGSKIEQLSSLDIHGFCAFNWDSETSSGKLRYFVPWHGRDEDYVTGSIQQYLTSLVHDKYGAQTQHWQQMSSSSGSLLSEYRDSHIRLSGQCEQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGD3</accession>
    <name>B1KGD3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326599.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4014"/>
    <dbReference type="EnsemblBacteria" id="ACA88270">
        <property type="protein sequence ID" value="ACA88270"/>
        <property type="gene ID" value="Swoo_4014"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4014"/>
    <dbReference type="eggNOG" id="ENOG502ZKX7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130970_1_0_6"/>
    <dbReference type="OMA" id="YANIKHE"/>
    <dbReference type="OrthoDB" id="1612022at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="15525" checksum="3D535B1E9B90CAA4" modified="2008-04-29" version="1">MAKPSLSTTQVRQIEKILYRWSGKLTWEELVDQLENELEITTTRQTLNSYSSISGVFKSTKTRLRGISENYQNSPNVSLEKASLLDKIEKLENEIIGLRTQNQQFQGLLNDIRMEAESTPLLMDLLISVKRKHQG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG9</accession>
    <name>RL21_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplU</name>
        <name type="ordered locus">Swoo_1004</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323644.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KGG9"/>
    <dbReference type="SMR" id="B1KGG9"/>
    <dbReference type="STRING" id="392500.Swoo_1004"/>
    <dbReference type="EnsemblBacteria" id="ACA85297">
        <property type="protein sequence ID" value="ACA85297"/>
        <property type="gene ID" value="Swoo_1004"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1004"/>
    <dbReference type="eggNOG" id="COG0261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061463_3_3_6"/>
    <dbReference type="OMA" id="HRQEITR"/>
    <dbReference type="OrthoDB" id="1949059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000143851" description="50S ribosomal protein L21">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <sequence length="103" mass="11512" checksum="5CE9AC69B2501E04" modified="2008-04-29" version="1">MYAVFQSGGKQHRVAEGHTVRLEKLEVATGETVEFDQVLLVADGETVHVGAPLVEGGKVVAEVVSHGRDEKVTIVKFRRRKHHDKKMGHRQWFTEVKITAINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGP4</accession>
    <name>B1KGP4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1079</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323718.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1079"/>
    <dbReference type="EnsemblBacteria" id="ACA85372">
        <property type="protein sequence ID" value="ACA85372"/>
        <property type="gene ID" value="Swoo_1079"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1079"/>
    <dbReference type="eggNOG" id="COG1714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053152_4_1_6"/>
    <dbReference type="OMA" id="FVFFWTR"/>
    <dbReference type="OrthoDB" id="1974702at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="17"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19361" checksum="2B0D1A00B911A9BB" modified="2008-04-29" version="1">MKESSMPNSEHANFPRAGFFRRCGAIVYDLLLAVAVYMIAGAIGFGVFTGLTSSGLIEMGNYEHVSDLLNGDSLYKGIYQFWIALCVGLFYISFWSYGGQTLGMRAWRLKVQHPNGQSLSMITAAARLVWSLLGIGNLWILINGDKLALQDMMTRSEVVQLSKEANQMRNWHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGQ9</accession>
    <name>B1KGQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325119.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2501"/>
    <dbReference type="EnsemblBacteria" id="ACA86778">
        <property type="protein sequence ID" value="ACA86778"/>
        <property type="gene ID" value="Swoo_2501"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2501"/>
    <dbReference type="eggNOG" id="ENOG502ZGX9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_874041_0_0_6"/>
    <dbReference type="OMA" id="FAESQYA"/>
    <dbReference type="OrthoDB" id="908011at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="283" mass="31949" checksum="036E7815C24DBEF2" modified="2008-04-29" version="1">MQTVSSNELLSTLSKVTIIGNANGKLDIPSSGATFIFNGTKPDNNQSGKAETLINISNGPFAGSTCPFVISGSLDEHDSESLTLQLIEIAQSLEKELNCWPSTGLVTIVLMSRLSTQIEVKRMSLLPSLKREMEMPIEEHLPCMVHNWLGERRIALAISVPNLSWPELQLTQPLSKEALDNQIELTDYNRCPFELLTQVHRHAHNELTSSADMLNILSYLSTTHIELWLQHSTQEKLLSCELMFFNQTPEQTASFWYLVDNQASQYLDDIRHRLAYCQQVFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS5</accession>
    <name>B1KGS5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type VI secretion-associated protein, VC_A0119 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2517</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325135.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2517"/>
    <dbReference type="EnsemblBacteria" id="ACA86794">
        <property type="protein sequence ID" value="ACA86794"/>
        <property type="gene ID" value="Swoo_2517"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2517"/>
    <dbReference type="eggNOG" id="COG3515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029347_1_1_6"/>
    <dbReference type="OMA" id="CLQHPAK"/>
    <dbReference type="OrthoDB" id="1255529at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010657">
        <property type="entry name" value="ImpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017739">
        <property type="entry name" value="T6SS-assoc_VCA0119"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06812">
        <property type="entry name" value="ImpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16989">
        <property type="entry name" value="T6SS_VasJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03362">
        <property type="entry name" value="VI_chp_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ImpA_N" evidence="2">
        <location>
            <begin position="11"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="467" mass="52027" checksum="2141AA5639F2BAF8" modified="2008-04-29" version="1">MTHQYIEKIAKPIAGDNPVGERLFDDVLFDFVEGQLMKVGSLSHAEVQWGEVETAVVSLLETRTKDLKLIIYLMQCLQYQASLERFSLSLGVLDIFMKEYWLTCYPAPGDRGVLPRRKYFSQIVQRTVKSGESIDTQFCEPQSKELLLKRLSSLLDSAEKLELPTEVLSSLATRLTRQLEQNENRVSATKSNAVSEPAEEAVSRSAPKLEIDSSNDKATKQTLLKVADFISEFETGTGLSLRIRRFATWSSVSGVPENANAAGETSLMPIAADRVSEYQSQLEKGADMALLRRVELSLTLSPFWLDGHHLSAQIAMALGQLEWAKAIHEDTAAFVERLPKLLMMSFKGGIPFANAETRTWLDEGYGRNSFEGNGQGVEQKRAEVVELADSGGLSVAFASLNEHLQQASEPRDAFYLRLLGADLKQSHQLSAMATVDYQVLYQQASHMVLADWEPTLMARLKQKANLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGW2</accession>
    <name>B1KGW2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14 15">UvrABC system protein B</fullName>
            <shortName evidence="14">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uvrB</name>
        <name evidence="20" type="ordered locus">Swoo_2554</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12 14 15">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325172.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2554"/>
    <dbReference type="EnsemblBacteria" id="ACA86831">
        <property type="protein sequence ID" value="ACA86831"/>
        <property type="gene ID" value="Swoo_2554"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2554"/>
    <dbReference type="eggNOG" id="COG0556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009621_2_1_6"/>
    <dbReference type="OMA" id="EYVDRMV"/>
    <dbReference type="OrthoDB" id="95696at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 14 15" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 14 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 14 15" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14 15" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="27"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="432"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="17">
        <location>
            <begin position="632"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="254"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="14">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACA86831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="671" mass="76271" checksum="D6FCC9995F451D3F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH00</accession>
    <name>B1KH00_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326641.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4056"/>
    <dbReference type="EnsemblBacteria" id="ACA88312">
        <property type="protein sequence ID" value="ACA88312"/>
        <property type="gene ID" value="Swoo_4056"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4056"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_6"/>
    <dbReference type="OMA" id="CFVTNTA"/>
    <dbReference type="OrthoDB" id="1204683at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16925">
        <property type="entry name" value="TetR_C_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="21685" checksum="CECFE1F9F6D3DD28" modified="2008-04-29" version="1">MRNAEFDREKVLRSAMTAFMDKGYGKTSMQDLTKATGLHPGSIYCAFDNKRGLLLAALEQYKIDRTTEFQGFFTGKKSVLAELKDYLDNTVQECISCEAAKACLLTKALNEMAQQDEEIQKIITENLANWQQGLADVFTLAKEKGELSAERDSQHLARFLAMGIYGLRTFAHTHPQGETLQELADQLFKDICA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH22</accession>
    <name>B1KH22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4078</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326663.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4078"/>
    <dbReference type="EnsemblBacteria" id="ACA88334">
        <property type="protein sequence ID" value="ACA88334"/>
        <property type="gene ID" value="Swoo_4078"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4078"/>
    <dbReference type="eggNOG" id="COG3686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110778_2_0_6"/>
    <dbReference type="OMA" id="GGYDNHH"/>
    <dbReference type="OrthoDB" id="2049059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="13679" checksum="C174E66AECF710DA" modified="2008-04-29" version="1" precursor="true">MTTLLICLFIAMLLPYLAKGPVAVAMAKAGGYDNAHPRDQQSKLTGFGARAVAGHQNAFESLLIFGLAVVTVIATNSVNETAVIFAIVHVIARIAYQVLYLIDKGTLRSLSWFVAIISSFTIFCQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH40</accession>
    <name>B1KH40_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326681.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4096"/>
    <dbReference type="EnsemblBacteria" id="ACA88352">
        <property type="protein sequence ID" value="ACA88352"/>
        <property type="gene ID" value="Swoo_4096"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4096"/>
    <dbReference type="HOGENOM" id="CLU_1766766_0_0_6"/>
    <dbReference type="OrthoDB" id="2205132at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="16548" checksum="94ACF774005F60AA" modified="2008-04-29" version="1" precursor="true">MIKKYFLISGCVLALSACGDATQSKIENYLTKAASKEGYQLKDVENIDGSYYATVKITNNEINTFENMYQMIQSNRSNIENYFAQVDELESAYSKKMNNLCPPTMNDNPQGAEFWQGVGEIKYFVISPKLPGQLFTFASTECLRSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH83</accession>
    <name>B1KH83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323737.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1098"/>
    <dbReference type="EnsemblBacteria" id="ACA85391">
        <property type="protein sequence ID" value="ACA85391"/>
        <property type="gene ID" value="Swoo_1098"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1098"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1073230_0_0_6"/>
    <dbReference type="OMA" id="WAVNLFN"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="259" mass="28111" checksum="8A4CE778E8BFD9DC" modified="2008-04-29" version="1">MQTVTVDIGGSKALFEMHFDGRTEQYKIPTGEHFNIDSLNQQLQELESDYGFKDYRLAIALPGLVQDNQLLSSKSLIGLNGLSKSDINTQAQTVLIVNDIDAGMQAVTDSRHDCELLVMCGTGIGMAISINGKLFTGAHGLAGELGHCRVMTESGEFSLEQLASGGSIQTREIKSQADLFRAGSYLGMGMAWAVNLFNPNRIWLAGGMMNNADYYRGCISALNEMALTAPLSQAKVARVDDMETIVCRGLKVMLDRSCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP0</accession>
    <name>B1KHP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325265.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2648"/>
    <dbReference type="EnsemblBacteria" id="ACA86925">
        <property type="protein sequence ID" value="ACA86925"/>
        <property type="gene ID" value="Swoo_2648"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2648"/>
    <dbReference type="HOGENOM" id="CLU_1593422_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="167" mass="19951" checksum="759B6CE9AFAC65B1" modified="2008-04-29" version="1">MKSLDFAFLCSFIRAKHYAPEENPYRLALKQLNFPLAFFLCFVTWLTLMQLGLMDKVNSYWPQKYVEPSKFNFFSPVTFILIPLWYGVYRFTKTYFLRESKQKEIRAYFKVKSIEQVPKFINVFWFLYLFSSPVVIFSKDPIIIGSVFAIVALMEIFVRYNYGTSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ2</accession>
    <name>B1KHZ2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PHB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4214</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326798.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4214"/>
    <dbReference type="EnsemblBacteria" id="ACA88470">
        <property type="protein sequence ID" value="ACA88470"/>
        <property type="gene ID" value="Swoo_4214"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4214"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620953_0_0_6"/>
    <dbReference type="OMA" id="HQNNITG"/>
    <dbReference type="OrthoDB" id="424481at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="47"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="270"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="441" mass="48209" checksum="CEF7715994777D70" modified="2008-04-29" version="1">MESQVQETKGSLVRRIGRRNIILISAFVTVLVVIATLISQMIAWNEADERLVHQSAFTGNLTVINQAGPYFKAFGTVSAYNKVISINFTGNSAAKASALVPLIPIRFLDTTTGDARGVARFRLPGNVPATESGQLRGLLKIHEEFGSQETLVSNLLLRATTENVKASARMMSVEQHYSGGNGQLSQDFSDQLVNGIFVTEQIFGTSSNEKSEELSNLSKQQRVTIKIKEGSNGKKLRNAPILGAYGITVVDASIIDIDYESKVNSRLEAQKQAAADEALARQNLKKAEQQARTEVALGEQAIAKQRAESEKLKIKEQIDAERVKANAIISAQQRVEVKAQLALEQAEILKQQRLEAMGMDVLAEARQRAKSAALDPKYVFDETLKAEIKIQTALFNSLGNSRLVPEIMIGGGQGEQSNGSEFMRLLAADAALNLKKRLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI27</accession>
    <name>B1KI27_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="8">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tyrS</name>
        <name evidence="10" type="ordered locus">Swoo_1212</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323851.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1212"/>
    <dbReference type="EnsemblBacteria" id="ACA85505">
        <property type="protein sequence ID" value="ACA85505"/>
        <property type="gene ID" value="Swoo_1212"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1212"/>
    <dbReference type="eggNOG" id="COG0162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024003_5_0_6"/>
    <dbReference type="OMA" id="YMMAKDS"/>
    <dbReference type="OrthoDB" id="402899at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02007">
        <property type="entry name" value="Tyr_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024108">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF1">
        <property type="entry name" value="PTHR11766:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="226"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="398" mass="44128" checksum="EC23652A469E2C2D" modified="2008-04-29" version="1">MADLDQALAEIKRGTDEILLEADLLEKLKEGRPLRIKLGADPTAPDIHLGHTVILNKMRTFQELGHEVIFLIGDFTGMVGDPSGKNSTRPPLTREQVLANAETYKQQVYKILDPAKTRIEFNSSWLEPLGAAGMIRLASKQTVARMMERDDFKKRYASGQSIAIHEFMYPLLQGYDSVALEADVELGGTDQKFNLLMGRELQKSKGQKPQTVIMMPLLEGLDGVKKMSKSAHNYIGVSEPAGEMFGKIMSISDDLMWRYLELLSFRPLSEIEQFKRDVEQGTNPRDIKIALAKEIIARFHDEAAAEGAHQEFINRFQKGAIPDDIEELEIAVGEGIAIANLLKEAGLVNSTSDGMRMIKQGAAKIDGAKIDDTRLQLTAGTSGVFQVGKRKFAKITLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC3</accession>
    <name>B1KIC3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">infA</name>
        <name evidence="6" type="ordered locus">Swoo_2698</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_011865366.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="SMR" id="B1KIC3"/>
    <dbReference type="STRING" id="392500.Swoo_2698"/>
    <dbReference type="EnsemblBacteria" id="ACA86974">
        <property type="protein sequence ID" value="ACA86974"/>
        <property type="gene ID" value="Swoo_2698"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2698"/>
    <dbReference type="eggNOG" id="COG0361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151267_1_0_6"/>
    <dbReference type="OMA" id="AHVSGKM"/>
    <dbReference type="OrthoDB" id="2066663at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="5">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="72" mass="8275" checksum="5D0C715ADBCBFE48" modified="2008-04-29" version="1">MAKEDNIEMQGTILETLPNTMFRVELENGHVVIAHISGKMRKNYIRILTGDKVTVQLTPYDLSKGRIVFRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KID6</accession>
    <name>B1KID6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325324.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86987">
        <property type="protein sequence ID" value="ACA86987"/>
        <property type="gene ID" value="Swoo_2711"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2711"/>
    <dbReference type="eggNOG" id="ENOG5031E8I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2119447_0_0_6"/>
    <dbReference type="OMA" id="LQASNWC"/>
    <dbReference type="OrthoDB" id="1940998at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="13240" checksum="3ADFF1544A14D0CD" modified="2008-04-29" version="1">MVTFKYDLNQDIVELQASNWCGLEQVYINGKRVSRKLNFGQHSEHEVKLHDGNPCKFQLLIDPSSEQMVCRIYRKNNLVASIKQGKENLSQSRRSLQNWAIFFTLSSLLLLLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIF7</accession>
    <name>B1KIF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein TolA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2732"/>
    <dbReference type="EnsemblBacteria" id="ACA87008">
        <property type="protein sequence ID" value="ACA87008"/>
        <property type="gene ID" value="Swoo_2732"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2732"/>
    <dbReference type="eggNOG" id="COG3064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073807_0_0_6"/>
    <dbReference type="OMA" id="FNLFRDI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019534">
        <property type="term" value="F:toxin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043213">
        <property type="term" value="P:bacteriocin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014161">
        <property type="entry name" value="Tol-Pal_TolA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06519">
        <property type="entry name" value="TolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02794">
        <property type="entry name" value="tolA_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="309" mass="35094" checksum="D12EC50A3D6E1D57" modified="2008-04-29" version="1">MRSDITIPLIISAGIHIGVIVIVAMGVDFSEKPKPQVQASAPAVQAVVVDQSKVAQHVERLKAEKKEAERKEKARQDEANRQVREARKEREREQARIKQLEQERKQKEVETKNAADAAKAAQLKQKQEKEKAAKAEADRKQKEKERKASEEAARKAAEKRKAEEAAAKKAEEERKRKAEAERKRKAEEEARRQQEQMMQDALAAEQASLSQTRNKQVTSEVSRYTSMIVATISRNVQQEESMRGKSCTVWVRLAKDGFVTSSRIVEGDPVLCRATQSAIQKVQRLPVSSEPDVYDKLKELNIIYRPKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP8</accession>
    <name>B1KIP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326871.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4289"/>
    <dbReference type="EnsemblBacteria" id="ACA88544">
        <property type="protein sequence ID" value="ACA88544"/>
        <property type="gene ID" value="Swoo_4289"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4289"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024648_6_2_6"/>
    <dbReference type="OMA" id="WCAVGDA"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="6"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="372" mass="41460" checksum="BCF4A761710DFA48" modified="2008-04-29" version="1">MINTKYDVVILGGGPAGLAAAIAIRTKTNASVLLVDRQNKGEVRVGENCPPETVLLLKQLGVAKEFYRGGHQTCPGYASVWGRDTPGYNDFIVNPQGPAWRLNRQAFDKMLADRAELCGAQISWSTRFIDAQKHSDESEGFILRLVKKSEDKECNVQARFVIDATGSTASFAGKLDINKSVDDELFATVRFSTLAHGRGSKQIQLEAFEHGWCYHALLPAEKVVSMVVTEKKHLATLREAEFQGFNDLLQSTTLIGPSLAKLDLEQSTYHTYCIRSGVLPAAEGCNWMAIGDAVASFDPIAAQGIYKGLSHGLQAGEKVLSWFENRENSQLRFSQQVKSQYGDYQRNRSHVYHLENRWSNAHFWLNRQHLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ68</accession>
    <name>B1KJ68_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325424.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2813"/>
    <dbReference type="EnsemblBacteria" id="ACA87088">
        <property type="protein sequence ID" value="ACA87088"/>
        <property type="gene ID" value="Swoo_2813"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2813"/>
    <dbReference type="eggNOG" id="ENOG5032UCI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094218_0_0_6"/>
    <dbReference type="OMA" id="ISHHENL"/>
    <dbReference type="OrthoDB" id="1318694at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766702" evidence="1">
        <location>
            <begin position="20"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="253" mass="28524" checksum="042F7E9DA9186CFF" modified="2008-04-29" version="1" precursor="true">MNNSALLLLLICFTTLAEASSTIDDPHSTNPPQGNPGKIVDYVASLEWDSNYISEGRNNLDKGGIFWSSIISHHENLTLYAIAGRADSMQYSEWNLGFEYTVSLKANLEMNLGYQNIQSYGDERFSDNELFSSLTYAGIEWLTPSLNYVYSLEARGYFIEAALHSSWHVSDALTVTPYIAQAFDFKYVTEEHNGKNHFQFGIEVEYQYNQNLVLSGHISHTLAQEDIKLEADLGTLESSLDHSFSGITLTWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA9</accession>
    <name>B1KJA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CheC, inhibitor of MCP methylation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4328</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326907.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4328"/>
    <dbReference type="EnsemblBacteria" id="ACA88581">
        <property type="protein sequence ID" value="ACA88581"/>
        <property type="gene ID" value="Swoo_4328"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4328"/>
    <dbReference type="eggNOG" id="COG1776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_848985_0_0_6"/>
    <dbReference type="OMA" id="IVLGQHR"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="331" mass="36265" checksum="84EE9B8BF02AF0AD" modified="2008-04-29" version="1">MPIPVLICDDSALARKQMARTLPKEWEVDITFANNGAEGIEAIKAGKGEVVFLDLNMPVMDGYEVLEIIQREDLPALVIVVSGDIQIKAHERVKALGALDFIQKPVSADAISNILQEYGILTIALGEGVADSPMIKVDLRDACQEIANVAMGRAADLLAKLLDVFVLLPIPNVNVLEVSELTMTLKATEEHSKVSALCQGFIGAGIAGEALLLFHDSSFKDMAKLMGLANPEDTNTEMEVMIDTGNVLIGAFLNGISEQLHMKFSQSHPVVLGRHCTVNDLIHDNSEKWSRTLAMEINYRIEDHDIQCDLLLLFTEDSLPTLNFKLGYLLE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-02-09" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW0</accession>
    <name>NUON_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit N</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoN</name>
        <name type="ordered locus">Swoo_2872</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325483.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJW0"/>
    <dbReference type="SMR" id="B1KJW0"/>
    <dbReference type="STRING" id="392500.Swoo_2872"/>
    <dbReference type="EnsemblBacteria" id="ACA87147">
        <property type="protein sequence ID" value="ACA87147"/>
        <property type="gene ID" value="Swoo_2872"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2872"/>
    <dbReference type="eggNOG" id="COG1007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_1_5_6"/>
    <dbReference type="OMA" id="NAWAPDA"/>
    <dbReference type="OrthoDB" id="1664448at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00445">
        <property type="entry name" value="NDH1_NuoN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010096">
        <property type="entry name" value="NADH-Q_OxRdtase_suN/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01770">
        <property type="entry name" value="NDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000391223" description="NADH-quinone oxidoreductase subunit N">
        <location>
            <begin position="1"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="3"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00445"/>
        </source>
    </evidence>
    <sequence length="473" mass="51616" checksum="55B6ECBF81059DB2" modified="2008-04-29" version="1">MSLHYLPAIIISIAILVLLLVIALKRNHQLAFYITGTGLCIACVSQCSLLSASHFSDELFTFSSMSGVLSVLLLGILIFLWLQLHTWLEKHEANHKEEFYLLLLLASLGALGMIVSEHFASFFLTLELMSLSFVGLIAYSHSQLSSQEAGVKYLILSAVASAFMLMGIAIVYLQTGNLSFQYLADNVNNTNPSSMLFTAGLIFILIGLLFKLSLVPCHLWVADIFEGAPLPTTALLSTVSKLASFVVLWKLFHLGNWQENQIVLTLIGVVAVASMLIGNLLALLQNSILRILAFSSISHFGYLLILLFLFNHNADLLDNPTFPLEALLFYLSAYLITLTGAFSILMKLEGGKSLEALTGLFWSKPLHAASLSIVMLSLAGIPLTLGFMGKFYLVTASVSYQVTWPLPFLVIASVIGLFFYLRVIMVMLSATQSPHSSPSTSGEVASLWFIILLIMGLGTFPALFADTIKSVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJY5</accession>
    <name>B1KJY5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2899"/>
    <dbReference type="EnsemblBacteria" id="ACA87172">
        <property type="protein sequence ID" value="ACA87172"/>
        <property type="gene ID" value="Swoo_2899"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2899"/>
    <dbReference type="eggNOG" id="COG3137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_743374_0_0_6"/>
    <dbReference type="OMA" id="QFIIGFG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007433">
        <property type="entry name" value="DUF481"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04338">
        <property type="entry name" value="DUF481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="333" mass="37844" checksum="79D377F1A6EDD404" modified="2008-04-29" version="1">MVPAQLYPPADSAFDWVQLTSFELLKGEIKTLYDDKLEFESDELDTLYIDWEDIKVLQSNGLVSVGFTDLSTKTGKLLVKDGKTYIGGEEFDRTKIMTIIAGEQTEANYWSSKISLGANLRSGNTKQLDYSAIANTQRRTTESRYNLDYLGNYSKTEGENNINNHRINTYFDWYLSKQFYLRPVFAEVYMDPIKNIQYKTTLGFGVGYDIIDSSKTEWSISGGPAYNYTKFDNVAPGEKEDEGSAALVVETYFDTEITSDIDFNTLYRLQYGSETSGGYTHHAVAGFSIELTDMFDLDLSFVWDHTNKPQPDSDNTIPKQNDYQFIIGFGIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD7</accession>
    <name>B1KKD7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324123.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1489"/>
    <dbReference type="EnsemblBacteria" id="ACA85777">
        <property type="protein sequence ID" value="ACA85777"/>
        <property type="gene ID" value="Swoo_1489"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1489"/>
    <dbReference type="eggNOG" id="ENOG5034AYM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2144130_0_0_6"/>
    <dbReference type="OrthoDB" id="2030030at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767434" evidence="1">
        <location>
            <begin position="24"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12262" checksum="33CB90E8FEC96025" modified="2008-04-29" version="1" precursor="true">MAIKLKSFLLILVLCFISPRSDASGGTGSGVIENIYVNNGWTMVHVPAITNNPDNCPSASYFAIRPSDANYITLHSTLLAAFMAEKPVRFWLSGCGGQNNNHPKIVSVWMYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKE0</accession>
    <name>B1KKE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324126.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1492"/>
    <dbReference type="EnsemblBacteria" id="ACA85780">
        <property type="protein sequence ID" value="ACA85780"/>
        <property type="gene ID" value="Swoo_1492"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1492"/>
    <dbReference type="eggNOG" id="ENOG5032Y7A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2083260_0_0_6"/>
    <dbReference type="OMA" id="CEAWGAN"/>
    <dbReference type="OrthoDB" id="2044307at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764997" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="117" mass="12469" checksum="D9772963A375E3A6" modified="2008-04-29" version="1" precursor="true">MKLIIMLCLMFTSFSSSAAWLNTTGKVKSISVYAGKDTILVNLDSAGTKINECSSPSTFAISSTNTPEQRARLYSTLLAAQAAGRSVTLAYNDVGNCEAWGANAHAYRRIVRISLGG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI9</accession>
    <name>RLMN_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="1">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmN</name>
        <name type="ordered locus">Swoo_1541</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324175.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKI9"/>
    <dbReference type="SMR" id="B1KKI9"/>
    <dbReference type="STRING" id="392500.Swoo_1541"/>
    <dbReference type="EnsemblBacteria" id="ACA85829">
        <property type="protein sequence ID" value="ACA85829"/>
        <property type="gene ID" value="Swoo_1541"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1541"/>
    <dbReference type="eggNOG" id="COG0820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029101_0_0_6"/>
    <dbReference type="OMA" id="QVGCSLD"/>
    <dbReference type="OrthoDB" id="1111428at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000350408" description="Dual-specificity RNA methyltransferase RlmN">
        <location>
            <begin position="1"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="100"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="1">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="168"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="(transient)" evidence="1">
        <location>
            <begin position="107"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <sequence length="373" mass="41634" checksum="74852C142A5D1887" modified="2008-04-29" version="1">MSEKKINLLDLDRKGLRALFTEMGEKPFRADQLMKWIYHFGVSDFDEMNNINKALRAKLNARCEIVAPEISSFQKSEDGTIKFAINVGQGQEVETVYIPEDDRATLCVSSQVGCALECTFCSTAQQGFNRNLTVSEIIGQVWRVADFIGFVKETGERPITNVVMMGMGEPLLNLKNVIPAMDIMLDDFGFSLSKRRVTVSTSGVVPALDKLGDALDVALAVSIHAPNDELRDVLVPVNKKYPLEEFLGGIRRYIAKSNANRGRVTVEYVMLDHINDSTDQAHELAKLMKDTPCKINLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGLTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKRMQDSQISVTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL9</accession>
    <name>B1KKL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325572.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87236">
        <property type="protein sequence ID" value="ACA87236"/>
        <property type="gene ID" value="Swoo_2965"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2965"/>
    <dbReference type="HOGENOM" id="CLU_2439127_0_0_6"/>
    <dbReference type="OrthoDB" id="2139849at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="90" mass="10274" checksum="7B9B89E03368E274" modified="2008-04-29" version="1">MGYITKPRAVSVIYQTRISSRIIEPFNNEFGEAEKALRKIGSNLWFSGLPKDLQDYLVSNTVECFDTWDMSMEQAATQVISAFEAMNSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP7</accession>
    <name>B1KKP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2993</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325600.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2993"/>
    <dbReference type="EnsemblBacteria" id="ACA87264">
        <property type="protein sequence ID" value="ACA87264"/>
        <property type="gene ID" value="Swoo_2993"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2993"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_18_3_6"/>
    <dbReference type="OMA" id="AGFCNIN"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="6">
        <location>
            <begin position="56"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="5">
        <location>
            <begin position="281"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="705" mass="79029" checksum="9B4145A109BC0027" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV9</accession>
    <name>B1KKV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327091.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4514"/>
    <dbReference type="EnsemblBacteria" id="ACA88765">
        <property type="protein sequence ID" value="ACA88765"/>
        <property type="gene ID" value="Swoo_4514"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4514"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_2_6"/>
    <dbReference type="OMA" id="LELKICW"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="317" mass="36118" checksum="438BF34E6D9B3E11" modified="2008-04-29" version="1">MPLEKKIDQLKDCDLNLLIALSVLLKEAHVTKAAKELGLSQSAMSQVLKRLRLMFEDPLLVKSHNGMTLTSKATAIESELKPLLNRVISILEGDRFNPATAQGRIRVMMNDVLAQLCITQLISELDKHAPGIELEYVTQKTDGFKMLRRGHLDLIVGFYDSVPKPIRSQAISRYPWQLVTLDPQANDYIDKIHNGQSIIEESPFKLLRYQYQEHNQAHMINALKAINAEEASYALTSGSLSTMTQALTAPYTVTLLPHYSVKIFEKHKAEDFIWLGDTIELDLKVCWNEHNRNLKLQKWFRQLISSILIKQLSNTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL00</accession>
    <name>B1KL00_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327132.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4556"/>
    <dbReference type="EnsemblBacteria" id="ACA88806">
        <property type="protein sequence ID" value="ACA88806"/>
        <property type="gene ID" value="Swoo_4556"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4556"/>
    <dbReference type="eggNOG" id="ENOG5030CSW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_588792_0_0_6"/>
    <dbReference type="OrthoDB" id="1547344at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767169" evidence="1">
        <location>
            <begin position="32"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="457" mass="51814" checksum="FA339D9D6AFC489F" modified="2008-04-29" version="1" precursor="true">MTYKIANIINTQRLKWVSVFLLAGASMNIQAKPLDYEKPTADIEGPRSCFWNRGPFSADPYINVAYPDANVFYWAATFTIPKGAKLEVDGEFAHARYQSLISYDERGRPQDSVADYLIAPKLNNTNPYQTGADRQAEERSYSIAVQTGMPPQIERGVMQRNTVRTDIYAPSYRKDQQLLIYRIYLPDEKASITGGVPLPEPVLTLSDGKRLRGGEACAALKTGQQLKIDPNALNISAEKYVALRDQADKPATWPATNPSSWYIQYDREFLLSMYSGEKVKMGRRSEGGFYPNLDNNYIRTIVNRKFGKVLVLRAKMPNISKSFYGERKHADADLRYWSICSNQSFANTRVTDCLFDEEVPLDKNGYYTIVVSREEDRPRNAKRECGVAWLEMAEDGDGLGDEDMAVVQIRNLLASPDFPHAVQKILKPGDEKAVMQEYFPKSHYMMPSMFEAVFPCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL15</accession>
    <name>B1KL15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4571</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327146.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4571"/>
    <dbReference type="EnsemblBacteria" id="ACA88821">
        <property type="protein sequence ID" value="ACA88821"/>
        <property type="gene ID" value="Swoo_4571"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4571"/>
    <dbReference type="eggNOG" id="COG3550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030167_1_0_6"/>
    <dbReference type="OMA" id="YLIVERY"/>
    <dbReference type="OrthoDB" id="1293681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="10"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="146"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="435" mass="49169" checksum="7D31CEF474DD75DF" modified="2008-04-29" version="1">MSGSNFHTLEMHFRGRVIGTIGFDIDTERFSIEYTKAWQENGFPISPKLPLDGQANSSQISIYLTNLLPENKGLDHLIEALGIAKSNTFALIKSIGFDTSGAILYLPVATKPPVTSFTPISKADLIKRIEDPEHWPMEVWDGKPRLSVAGVQSKLNLFHTDTEYGFGEGELCSTHIIKFEKSNQQHLVLNEFMTMTLADLIGMQVAKVEILPIGKYKALSVTRFDRMYDPERHIVMRRHQIDACQALGFSVARKYERYLGSGRDVRDIREGVSLEKLFSIAEHCANPAQAKFDMLRWTIFNLLVCNADSHGKNYSFYVTPNGLEPTPWYDLVNVQMYPDFDQELAMAIGDEFEADKIHAYQLMTFAEECGIKQNILELTLKQLAKAIIGNLDKAANQAGELTDAESEYVGAYKATIQARCEYYLTQVEEMKHIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL97</accession>
    <name>B1KL97_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LemA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0137</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322787.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0137"/>
    <dbReference type="EnsemblBacteria" id="ACA84438">
        <property type="protein sequence ID" value="ACA84438"/>
        <property type="gene ID" value="Swoo_0137"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0137"/>
    <dbReference type="eggNOG" id="COG1704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056714_3_0_6"/>
    <dbReference type="OMA" id="YNNAVQA"/>
    <dbReference type="OrthoDB" id="1573349at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="189" mass="20967" checksum="78EBA44B3FF2B743" modified="2008-04-29" version="1">MDGVLLGLGLVVIIAYLWYVSLVKKRNAGREALSGIDVQLKKRANVVPNILTIAKKFMDHEKSLLTEITELRTQVTNSYDNSDATEIKQHLAAAERLNSKMGQLMVTVEDYPELKSDNTMLQAMQTYNEVEAHISAARRFYNASVTELNNAVEIFPGSIIASMANIKVMPFYEADEAAKAPVNAADFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB2</accession>
    <name>B1KLB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1549"/>
    <dbReference type="EnsemblBacteria" id="ACA85837">
        <property type="protein sequence ID" value="ACA85837"/>
        <property type="gene ID" value="Swoo_1549"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1549"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1119520_0_0_6"/>
    <dbReference type="OMA" id="MCADIDY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="53"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="255" mass="28887" checksum="2A4FD01474F1A968" modified="2008-04-29" version="1">MSLALHVTAPSTALYTDLSGYYDLMCADIDYKAQSDHIRRLNRLFGNGASTHLDLACGTGPHIRHFIDYGFQSCGLDINQPMLDLAQVRCPEAEFTLQDMCSFRVNNPVDLITCFLYSIHYNDGICKLKQCLSSVYNALSEGGIFCFNAVEKTKIDNRAFVRHSTEFNDSQFTFSSGWNYSGAGERQSLKLSIEKSNEQESQVWQDEHPMVAVSFDELEQLLLPHFEVHIFEHDYDKITPLQPTSGNAIFVCVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLF7</accession>
    <name>B1KLF7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-glutamate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1596</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="2.1.1.80"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.80" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324228.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1596"/>
    <dbReference type="EnsemblBacteria" id="ACA85882">
        <property type="protein sequence ID" value="ACA85882"/>
        <property type="gene ID" value="Swoo_1596"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1596"/>
    <dbReference type="eggNOG" id="COG1352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025854_0_2_6"/>
    <dbReference type="OMA" id="PGIIYKA"/>
    <dbReference type="OrthoDB" id="1378151at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.155.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036804">
        <property type="entry name" value="CheR_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="277" mass="31463" checksum="561F92D632EA1751" modified="2008-04-29" version="1">MPNKSLAEAEYTQFRLFLEQHSGIVLGDNKQYLVRSRLAPLMGQYNLPSLSEVVKHSMKPTERQLRASVIDAMTTNETLWFRDRYPFELLSNKLLPEYSKLGRPLKIWSAACSSGQEPYSLAMTILEYQQKKPGTLPGNASILATDLSPSMLERCKNAEYDNLALGRGLSEERKRQFFTATNDGTMVIKDNVKRLVNFRAHNLLESYTLLGKFDIIFCRNVLIYFSPEAKAKILRQFAAALNPKGILFLGASESIAGLTEEFDMIRCNPGIYYQKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLM5</accession>
    <name>B1KLM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325658.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3051"/>
    <dbReference type="EnsemblBacteria" id="ACA87322">
        <property type="protein sequence ID" value="ACA87322"/>
        <property type="gene ID" value="Swoo_3051"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3051"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_6"/>
    <dbReference type="OMA" id="MSGADAY"/>
    <dbReference type="OrthoDB" id="1729688at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="122" mass="13831" checksum="FD09F0D8CE64DDB0" modified="2008-04-29" version="1">MKKILVVDDQLAMRNMFKKILTSDKFQIELAEDGALAYRAAQLVDYDMVITDYYMPHLNGIELTDKLRALRAYIGIPILIVSTAKNTKFKEEAKGAGATGWFSKPIKQDELLPTVLQLLNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLN7</accession>
    <name>B1KLN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325670.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3063"/>
    <dbReference type="EnsemblBacteria" id="ACA87334">
        <property type="protein sequence ID" value="ACA87334"/>
        <property type="gene ID" value="Swoo_3063"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3063"/>
    <dbReference type="eggNOG" id="COG3977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053657_0_0_6"/>
    <dbReference type="OMA" id="HAHQCLR"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="67"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="420" mass="47012" checksum="BD9A9795DB3B84F3" modified="2008-04-29" version="1">MQFSKFGEKFNRYSGITRLMDDLNKGLRTPGAIMLGGGNPGAIPEMLDYFHQATADMLENGELVSALGNYDGPQGKNTFLTALAALLKEQYGWDISEKNISLTNGSQSAFFYLFNLLAGKQLDGSHKKILLPLAPEYIGYSDAGLDEDIFISYRPEIEHLDNRMFKYHVDFEHLEVDDSVAAICVSRPTNPTGNVLTDTEIFKLDKLAQDNGIPLIIDNAYGTPFPNIIFEEVTPFWNKNTILCMSLSKLGLPGVRCGIVIANEEITQALTNLNGIISLAPGGFGPAIAKHMIDSGDLLRLSESVIKPFYQDRAKFAVSLLQESITDNRFKIHKPEGAIFLWLWFDELPISTMELYERLKARGVLIVPGDYFFFGQKEQSEEKWEHSHQCLRMNYVQDEAKMRDGIAIIAEEVIKAYANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ4</accession>
    <name>B1KLQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325687.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3080"/>
    <dbReference type="EnsemblBacteria" id="ACA87351">
        <property type="protein sequence ID" value="ACA87351"/>
        <property type="gene ID" value="Swoo_3080"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3080"/>
    <dbReference type="eggNOG" id="ENOG5033J1U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2540728_0_0_6"/>
    <dbReference type="OrthoDB" id="2081411at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9335" checksum="8E222B46CDC7916A" modified="2008-04-29" version="1">MKYLLFIFFFVLCGCESSQDMFKSQSSDGGELVDTGIRCQMMARTGSNKKTKVCRTAQQRAKDETDAERSLNKLQKTGMTLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS6</accession>
    <name>B1KLS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3102</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325709.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3102"/>
    <dbReference type="EnsemblBacteria" id="ACA87373">
        <property type="protein sequence ID" value="ACA87373"/>
        <property type="gene ID" value="Swoo_3102"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3102"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_0_6"/>
    <dbReference type="OMA" id="YIAYNVM"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765033" evidence="3">
        <location>
            <begin position="22"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="4">
        <location>
            <begin position="75"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="549" mass="61556" checksum="D439D991593D1FE4" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW5</accession>
    <name>B1KLW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327170.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4595"/>
    <dbReference type="EnsemblBacteria" id="ACA88845">
        <property type="protein sequence ID" value="ACA88845"/>
        <property type="gene ID" value="Swoo_4595"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4595"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078753_0_0_6"/>
    <dbReference type="OMA" id="QMIIANH"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="101"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="29782" checksum="2C882FD89410DDB2" modified="2008-04-29" version="1">MNDSVLASSASTSPRLTGLAYLPRWLGGVSCYIAFGLGGLLSSLTILPLLRFWPGTTEQRVSRVQKAVHHMFRGFVQMLTWAGVIKVTPVNLERLSLAKGKVVIVNHPTLVDVVVLISLMPNAGCIVKQGLWRNPFMRGVVACAGYIPNRGAELLLKDCKRVLDSGTNLIIFPEGTRTVLGTKINPFARGAANIALRTHTDLVPVVLRTDSPGLTKQEAWYQIPRRTIGMHVEVGDPLLHIRYDAQEGGDAKMARQLTRDLEDYYKKELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLX1</accession>
    <name>B1KLX1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327176.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4601"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88851">
        <property type="protein sequence ID" value="ACA88851"/>
        <property type="gene ID" value="Swoo_4601"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4601"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_15_0_6"/>
    <dbReference type="OMA" id="HTKLFFG"/>
    <dbReference type="OrthoDB" id="469211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="6">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="567" mass="65321" checksum="C5392E6F2CD7398D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLY8</accession>
    <name>Y4618_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0761 membrane protein Swoo_4618</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_4618</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0761 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327193.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLY8"/>
    <dbReference type="STRING" id="392500.Swoo_4618"/>
    <dbReference type="EnsemblBacteria" id="ACA88868">
        <property type="protein sequence ID" value="ACA88868"/>
        <property type="gene ID" value="Swoo_4618"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4618"/>
    <dbReference type="eggNOG" id="COG1295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032288_0_0_6"/>
    <dbReference type="OMA" id="KQPKFRW"/>
    <dbReference type="OrthoDB" id="1421045at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00672">
        <property type="entry name" value="UPF0761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023679">
        <property type="entry name" value="UPF0761_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000131566" description="UPF0761 membrane protein Swoo_4618">
        <location>
            <begin position="1"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="336" mass="37412" checksum="74D30768B46743B4" modified="2008-04-29" version="1">MKKKINLTQFQTLMLSIWHFMIHLKQRLAEDQINIRAGHLAYVSLLSLVPMVAVTMSMLSAFPVFQGIRGQIEDFIYNNFIPSAGDSVQVYINEFVDNASKGTAVGIAALMVVAIMLISSIDKSLNSIWHTKEKRSMVISFSMYWMVLTLGPVLMGASLVATSYVVSLKVFNGSDLSGVVPLLVERLPMLFSVATFLLIYMVVPNTKVKFFHALLGAIVAALMFEFGKKGFALYLTKFPTYEAIYGALATIPILFLWVYLSWMIVLLGAVITAAMPEYLDKKQSAVEDKNGEKEVVSQVPDVSFSISELPQEQSQEQSQEPSLKPVEESIKESRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM09</accession>
    <name>B1KM09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4639</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327213.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4639"/>
    <dbReference type="EnsemblBacteria" id="ACA88889">
        <property type="protein sequence ID" value="ACA88889"/>
        <property type="gene ID" value="Swoo_4639"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4639"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896881_0_0_6"/>
    <dbReference type="OMA" id="LKYSFWM"/>
    <dbReference type="OrthoDB" id="1635457at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018704">
        <property type="entry name" value="TPR_21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09976">
        <property type="entry name" value="TPR_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_21" evidence="4">
        <location>
            <begin position="88"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="143"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="35224" checksum="4EF5399D9C14730D" modified="2008-04-29" version="1">MDSNVSISQLIDSAEQHFQFGAYTRGIECLREALSLEPDNGFLHSYLSFALIETKRRTAALYEAEIGLSLSPDSSYGHYTLGYAYLVNQKFALASEHLDNAIEREPDNAMYHLLKSRIFFQQNKYQEALKTIKHALELAPNNCDVLTEYGDILLQLGKVDEAAEFYQNALQRGPQNINGLIGMGTVLLKKNQVQEAREHAIWALQQAPDYAPALRLFTQIKARSNPVMGVWWRLNNWLSNGSNTRMVVLLISGFLLFQVASIVLEDLGHKSVGEVVSMFWLGIVIYSWIGPAWFNRMLKKELETVSLDKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM59</accession>
    <name>B1KM59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome oxidase assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322821.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0171"/>
    <dbReference type="EnsemblBacteria" id="ACA84472">
        <property type="protein sequence ID" value="ACA84472"/>
        <property type="gene ID" value="Swoo_0171"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0171"/>
    <dbReference type="eggNOG" id="COG1612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041525_0_0_6"/>
    <dbReference type="OMA" id="HRYFAGT"/>
    <dbReference type="OrthoDB" id="1135592at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="327" mass="35924" checksum="728C4656332A9EA7" modified="2008-04-29" version="1">MQIPSLLKITIIFTLCVILMGAYTRLSDAGLGCPDWPGCYGMLKVPSQAHELSQVQATFPGHEVEPKKAWLEMIHRYIAGALGLLVLLIFILCLKKDEAPKKLPGLIALLIVFQAALGMWTVTMKLMPVVVMSHLIGGFSLIALLLLLYLRTKPLRIPGGDAIARKLAPLALICLGVLILQIIIGGWTSSNYAALACTTLPICEGDWYNNLKLAQAFNPFQGEHDTYEFGVLDYASRMTIHVVHRFWAVVTAAMLFWLAFKLYQQSQSSLLKRSALLLVLLVCLQVALGISNVVLHLPLGVAVSHNAGAALLLLNLVFINYALWRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMA6</accession>
    <name>B1KMA6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenylacetate-CoA oxygenase, PaaJ subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322868.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0218"/>
    <dbReference type="EnsemblBacteria" id="ACA84519">
        <property type="protein sequence ID" value="ACA84519"/>
        <property type="gene ID" value="Swoo_0218"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0218"/>
    <dbReference type="eggNOG" id="COG2151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082133_0_0_6"/>
    <dbReference type="OMA" id="EPFDHFK"/>
    <dbReference type="OrthoDB" id="1668114at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011883">
        <property type="entry name" value="PA_CoA_Oase4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02159">
        <property type="entry name" value="PA_CoA_Oxy4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="33"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="19256" checksum="D5D44A0E0CF57036" modified="2008-04-29" version="1">MTLSSATHSATINTVTVEYAARRKFRLNHEHGKIFDLLDAVYDPELTGVSLWDLGVLQNVSQQGAQWLVTISPTYSGCPAIDIMIEDIKVCLTNAGMEPVKVETQLSPAWTTDWVSPAGKTAMISHGIAACESQVICPQCHSQHVSRLSQFGSTSCKALYRCLDCLESFDYFKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB3</accession>
    <name>B1KMB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Regulatory PhaM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0225"/>
    <dbReference type="EnsemblBacteria" id="ACA84526">
        <property type="protein sequence ID" value="ACA84526"/>
        <property type="gene ID" value="Swoo_0225"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0225"/>
    <dbReference type="eggNOG" id="COG0663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064827_4_2_6"/>
    <dbReference type="OMA" id="MPVYQID"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="199" mass="22154" checksum="C1770C4FE39CEAA0" modified="2008-04-29" version="1">MPIFAIEQHIPVIEPTSFIHPNATIIGDVIIGKHCYIGSNACLRGDFGRIEIHDFCNVQDNCVLHSFPLQACVLEEYSHIGHGAILHGCTIRRHSLVGINAVVMDFADIGAESIIGAASFVKSRFNCPARSMLLGSPAKIVRQVSDEEFQWKTRGTDEYIELTRRCQTSLREVTPLTTVEENRPMFQPAQVHQPKNSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMD5</accession>
    <name>B1KMD5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VacJ family lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MlaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324279.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1647"/>
    <dbReference type="EnsemblBacteria" id="ACA85933">
        <property type="protein sequence ID" value="ACA85933"/>
        <property type="gene ID" value="Swoo_1647"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1647"/>
    <dbReference type="eggNOG" id="COG2853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059326_3_2_6"/>
    <dbReference type="OMA" id="ERHKQDF"/>
    <dbReference type="OrthoDB" id="1588560at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007428">
        <property type="entry name" value="MlaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30035">
        <property type="entry name" value="PTHR30035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04333">
        <property type="entry name" value="MlaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01805">
        <property type="entry name" value="VACJLIPOPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765054" evidence="3">
        <location>
            <begin position="23"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="282" mass="32161" checksum="07A4805C35F998FF" modified="2008-04-29" version="1" precursor="true">MKLNRIMLIVASLIISPIAVSGQDVLVKHVYKEEVHQERASLDGGVNLDIEPETSPTVTISYNDPRDPIEGFNRAMWDFNYHVMDRYLYRPVSHGYKDYIPLPVKTGVNNFVTNLEEPSTLVNNTLQGKWSWAANAGGRFTINTTMGLLGVIDVAGMMGLPRKQDEFNEVLGYYGVPNGPYFMAPFLGPYVTRELASDWVDGLYFPLSEFTIWQSLLKWGLKSLHQRAEAIDQERLVDNALDPYTFVKEAYFQHMDYKVYDGDVPVDLSEDELLDEYLDELD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KML5</accession>
    <name>SYE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="1">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gltX</name>
        <name type="ordered locus">Swoo_1728</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324359.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KML5"/>
    <dbReference type="SMR" id="B1KML5"/>
    <dbReference type="STRING" id="392500.Swoo_1728"/>
    <dbReference type="EnsemblBacteria" id="ACA86013">
        <property type="protein sequence ID" value="ACA86013"/>
        <property type="gene ID" value="Swoo_1728"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1728"/>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015768_6_0_6"/>
    <dbReference type="OMA" id="WDEGPFF"/>
    <dbReference type="OrthoDB" id="1409413at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000090107" description="Glutamate--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <sequence length="469" mass="52814" checksum="8DAF7FD932D9B1C9" modified="2008-04-29" version="1">MTVKTRFAPSPTGFLHVGGARTALYSWLYARANQGEFVLRIEDTDLERSTPEACAAILEGMEWLNLNWDEGPYYQTKRFDRYNEIIVQMLEQGTAYKCYCSRERIDTMREEQAAKGEQQKYDGCCRDKAPRDTDEPFVVRFKNPTEGSVVFDDHVRGHIEFANSTLDDLIIARTEGTPTYNFCVVVDDWDMGITCVVRGEDHINNTPRQINILKALGAPVPEYAHVSMILGDDGAKLSKRHGAVGVMQYRDDGYLPEALLNYLVRLGWSHGDQEVFSIDEMKQFFSLDDINKAASAFNTDKLIWLNQHYIKELDPEYVASHLEWHMADQNIDTSNGPKLSEVVSALSERAKTLKELAASSRYFFEDFAEFDETAAKKHLRGVALEPLTLFQSKLAGLNEWTLEAIHQAIEDTAAELEVGMGKVGMPLRVAVTGAGMSPAVDLTIFLVGKVRAEQRISKAIEFVANRINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMR7</accession>
    <name>B1KMR7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dystroglycan-type cadherin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3174</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325781.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3174"/>
    <dbReference type="EnsemblBacteria" id="ACA87445">
        <property type="protein sequence ID" value="ACA87445"/>
        <property type="gene ID" value="Swoo_3174"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3174"/>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_225908_0_0_6"/>
    <dbReference type="OMA" id="YRYTVQN"/>
    <dbReference type="OrthoDB" id="30278at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044016">
        <property type="entry name" value="Big_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19077">
        <property type="entry name" value="Big_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766869" evidence="2">
        <location>
            <begin position="20"/>
            <end position="2715"/>
        </location>
    </feature>
    <feature type="domain" description="CADG" evidence="3">
        <location>
            <begin position="1540"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="2715" mass="283545" checksum="737681009B12FC9E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN66</accession>
    <name>B1KN66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0262"/>
    <dbReference type="EnsemblBacteria" id="ACA84563">
        <property type="protein sequence ID" value="ACA84563"/>
        <property type="gene ID" value="Swoo_0262"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0262"/>
    <dbReference type="eggNOG" id="ENOG5032SEP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106724_0_0_6"/>
    <dbReference type="OMA" id="YSLDCER"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25714" checksum="9123BCE7C615ADBA" modified="2008-04-29" version="1" precursor="true">MASLQAFLFLSVASMEPVISALLFYTLIQRDEGLEKDVVTKSSDSMFENIHAFEGDDAIDWCHIRESIKVLILAMAQIELSLTDGEHNVTNLGALFTDMADHLGEVNDFLSTQSDTPVLVMAHSTILVDKVNEGVVAFQFYDRISQRLQHVIMGLALMEEVLSSKERRTSQDAWKKLQEGIQESYSLDCERKMFDLLLKGTPVHEALKLYKEEYQKEETEDDIELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN86</accession>
    <name>B1KN86_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0282</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CpxP/Spy family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322932.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0282"/>
    <dbReference type="EnsemblBacteria" id="ACA84583">
        <property type="protein sequence ID" value="ACA84583"/>
        <property type="gene ID" value="Swoo_0282"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0282"/>
    <dbReference type="eggNOG" id="COG3678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124352_1_0_6"/>
    <dbReference type="OMA" id="KMFRGLD"/>
    <dbReference type="OrthoDB" id="1906314at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd09916">
        <property type="entry name" value="CpxP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012899">
        <property type="entry name" value="LTXXQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07813">
        <property type="entry name" value="LTXXQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034445">
        <property type="entry name" value="CpxP_Spy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767232" evidence="6">
        <location>
            <begin position="27"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17709" checksum="674A51959270A5DB" modified="2008-04-29" version="1" precursor="true">MKKNTLKAGLLAIVASTTLMASSVYAGDDHQHHGKSHHMKGERSGHHGDIRKMFRGLDLTDTQKAEIKALVKEQRKAMKEEQVSKEERSAHRSEFFALISADNFDEAKAQALIEKKQQKRQEKGVAMLKIQNEVYQLLTPEQKVKFKEKFERRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN97</accession>
    <name>B1KN97_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322943.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0293"/>
    <dbReference type="EnsemblBacteria" id="ACA84594">
        <property type="protein sequence ID" value="ACA84594"/>
        <property type="gene ID" value="Swoo_0293"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0293"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_6"/>
    <dbReference type="OMA" id="YFWIMAK"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="267" mass="28697" checksum="7AD00CCA823FF3EC" modified="2008-04-29" version="1">MDGLNGKVIIITGASEGIGRALALSMAPLGCKLVLSARNESRLLSLAHEIESQGEPPLVFATDVTSQSQCQELIDATVEHFGCLDILINNAGMTMWSKFDELSDLSVLERIMQVNYLGPAYLTHAALPQLKLTQGQVVVVASLAGLTGVPARAGYAASKHAVMGFFESLRIELAEHNVAVTTLCPDFVTTQAHKRALDADGEPLGQTPIQESRVMSAEECARMMLPVISGRNRMMITSLRGKLGRFVKLVAPGMIDRMARRASSSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNK3</accession>
    <name>B1KNK3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chaperone protein HtpG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Heat shock protein HtpG</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">High temperature protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">htpG</name>
        <name evidence="7" type="ordered locus">Swoo_1796</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Molecular chaperone. Has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324426.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1796"/>
    <dbReference type="EnsemblBacteria" id="ACA86080">
        <property type="protein sequence ID" value="ACA86080"/>
        <property type="gene ID" value="Swoo_1796"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1796"/>
    <dbReference type="eggNOG" id="COG0326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006684_3_0_6"/>
    <dbReference type="OMA" id="MRRMKEM"/>
    <dbReference type="OrthoDB" id="246194at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HATPase_c" evidence="6">
        <location>
            <begin position="27"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="A; substrate-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="C" evidence="5">
        <location>
            <begin position="564"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="638" mass="71966" checksum="4A41AA1A16319787" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP31</accession>
    <name>B1KP31_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Molybdopterin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4813</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327379.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4813"/>
    <dbReference type="EnsemblBacteria" id="ACA89062">
        <property type="protein sequence ID" value="ACA89062"/>
        <property type="gene ID" value="Swoo_4813"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4813"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_1_1_6"/>
    <dbReference type="OMA" id="FFMGSAK"/>
    <dbReference type="OrthoDB" id="83812at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="9">
        <location>
            <begin position="61"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA89062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="949" mass="106194" checksum="73D076F759BAD29D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP73</accession>
    <name>B1KP73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sporulation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0342</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322992.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0342"/>
    <dbReference type="EnsemblBacteria" id="ACA84643">
        <property type="protein sequence ID" value="ACA84643"/>
        <property type="gene ID" value="Swoo_0342"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0342"/>
    <dbReference type="eggNOG" id="COG3267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_564853_0_0_6"/>
    <dbReference type="OMA" id="WLAQRYL"/>
    <dbReference type="OrthoDB" id="920552at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="26"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="2">
        <location>
            <begin position="373"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="464" mass="51909" checksum="881CC3DA6254F40D" modified="2008-04-29" version="1">MTFKDSILLPSQENLLQRLQHVSLYGQQLLVVTGQNGSGKTRLITSLINELDDFSSALVLCPKHCDNSEIRRKILVQLLTDPVFDDETPLAETLLRFADSLPQSCFIVLDDAHHLSIELIAECIVLSQLSIAGKSISITLTSTEEFFYHLVEQLPETQQDNLLSINIEPLTAQEKEALYYTLLSRSEQAPFTPREIVRAQLEKQSGTPQEVVNLLELALHGKEVEVPKSAKYKWIISIALLLLLSLGAYLLLPKEARDEKISSPAKLVLDSSSEMNWLANYGKNLLEADFSAEKKEGKAELISSNTASVDSTLTQQAASTEPQSEPHKGKMVDESTSLVNHDEVEVFKGLGEIKSSQLPHKVNVEPKIEPIALKGYTLQLASVKKQESLDNLLKRFSGESDVKVARYGEFWVVLLGEFSDINLARIKSKQMVNKYQLTTPWIRQWKDLSGYKVQDSIPARDIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA2</accession>
    <name>B1KPA2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating enzyme</fullName>
            <ecNumber evidence="4">4.4.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-(hydroxymethyl)glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gfa</name>
        <name evidence="6" type="ordered locus">Swoo_0373</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-(hydroxymethyl)glutathione = formaldehyde + glutathione</text>
            <dbReference type="Rhea" id="RHEA:22488"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="4.4.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (glutathione route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323021.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0373"/>
    <dbReference type="EnsemblBacteria" id="ACA84672">
        <property type="protein sequence ID" value="ACA84672"/>
        <property type="gene ID" value="Swoo_0373"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0373"/>
    <dbReference type="eggNOG" id="COG3791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090716_0_0_6"/>
    <dbReference type="OMA" id="ECGTHMY"/>
    <dbReference type="OrthoDB" id="1555973at2"/>
    <dbReference type="UniPathway" id="UPA00562">
        <property type="reaction ID" value="UER00621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051907">
        <property type="term" value="F:S-(hydroxymethyl)glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00723">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014185">
        <property type="entry name" value="Formald_GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033318">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02820">
        <property type="entry name" value="formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="20"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="185" mass="19879" checksum="746BBA50FDA24902" modified="2008-04-29" version="1">MKVLIHPQVDNGVTQSQEGFSGGTLGCQCQAQRVEVSVTAQTAHNHVCGCSKCWKPEGALFAQIAVVSRDNVQVINNADKLMVVDESAAIQRHACKECGTHMYGRIENAAHPFYGLDFVHTELSSEEGWSQPEFAAFVSSIIESGASADSMADVRQTLKDLGLEPYDCLSPALMDAIAVHLAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE6</accession>
    <name>B1KPE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323065.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0418"/>
    <dbReference type="EnsemblBacteria" id="ACA84716">
        <property type="protein sequence ID" value="ACA84716"/>
        <property type="gene ID" value="Swoo_0418"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0418"/>
    <dbReference type="eggNOG" id="COG0641">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009273_10_0_6"/>
    <dbReference type="OMA" id="IFDEWYA"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034491">
        <property type="entry name" value="Anaerob_Ser_sulfatase-maturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023867">
        <property type="entry name" value="Sulphatase_maturase_rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43273">
        <property type="entry name" value="PTHR43273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13186">
        <property type="entry name" value="SPASM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00285">
        <property type="entry name" value="anaerobic_Ser-type_sulfatase-m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01384">
        <property type="entry name" value="thioether_bond_formation_requi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04085">
        <property type="entry name" value="rSAM_more_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="27"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="431" mass="48972" checksum="C10FF6E0613EACCB" modified="2008-04-29" version="1">MVQYSMKQSTYMDAAPLLSAEKDLNPHPAYVRRFHAMAKPTGSRCNIDCQYCFYLHKKDLLGQPQQSHMSDETLSLFIQNYIDSQDGDEIIFSWQGGEPTLMGLDFFKKVIQLQQRYCPLGVTIKNDLQTNGVLLNKEWAIFLKQHDFLVGLSIDGPQELHDMYRVTRSGKPTFVLVMAAARILKKYGVQFNALAVINRKNVLYPKEVYRFLTQELGATYIQFTPCVEGNNFTQTAPQFWNEQMIPIIGSELSKPGHPMSVVTSWSVDPDDWGRFLISVFDEWVNNDLGRVLVNLFETAVAQTMGLPAQICVMAEFCGKGIAVEHDGKVYSCDHYVYPEYELGNIHQSSLNNLVFSTRQETFGMAKRDSLPNYCKSCPHLNLCWGECPKNRLIRTPDGELGLNYLCSGLSQFFEHAKPILNGIAAILERKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPK0</accession>
    <name>B1KPK0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent dethiobiotin synthetase BioD</fullName>
            <ecNumber evidence="5">6.3.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DTB synthetase</fullName>
            <shortName evidence="5">DTBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Dethiobiotin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bioD</name>
        <name evidence="6" type="ordered locus">Swoo_1869</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(7R,8S)-7,8-diammoniononanoate + ATP + CO2 = (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dethiobiotin synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1869"/>
    <dbReference type="EnsemblBacteria" id="ACA86153">
        <property type="protein sequence ID" value="ACA86153"/>
        <property type="gene ID" value="Swoo_1869"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1869"/>
    <dbReference type="eggNOG" id="COG0132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072551_0_0_6"/>
    <dbReference type="OMA" id="SPHWAAE"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="PTHR43210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006755">
        <property type="entry name" value="DTB_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00347">
        <property type="entry name" value="bioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="117"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="206"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="23206" checksum="F0C762D2973465A0" modified="2008-04-29" version="1">MIYFVTGTDTDCGKTFISSALLCKAASQGRASLGLKPIASGCEETELGLRNSDALSLIAQSTIELDYEQVNPVSFKPAIAPHIAAMQTSVDISPDTVIKHLSPTLSLVNETDFCLVEGAGGWRLPLGEGAFLSQAVQSLSLPVILVVGVKLGCLNHAVLTQEAILADGLEIAGWVGNIVDADTSCIEENLASLHQLMSSPCLGVVPHLSNGSAEEAAKYLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPP0</accession>
    <name>B1KPP0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OmpA domain protein transmembrane region-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324539.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1909"/>
    <dbReference type="EnsemblBacteria" id="ACA86193">
        <property type="protein sequence ID" value="ACA86193"/>
        <property type="gene ID" value="Swoo_1909"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1909"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106646_1_0_6"/>
    <dbReference type="OMA" id="DTTGFYV"/>
    <dbReference type="OrthoDB" id="2018542at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006315">
        <property type="entry name" value="OM_autotransptr_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01414">
        <property type="entry name" value="autotrans_barl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767539" evidence="1">
        <location>
            <begin position="23"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="9"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="184" mass="19764" checksum="A9C2B02773580A96" modified="2008-04-29" version="1" precursor="true">MKTLTIAAASLLAIFASSNVAAANDHSGFYVGGSLGQLKVKTEDSDNGLGFGAYGGYNFNDWFGLEANMYLSGDLGGNGYDLGAGTFAFTPKFTYQINDTFAVYGKVGIASMAVVYRPDRGIDEDFTGFGWVYGVGVNASITENLNIRLGYDIVKGDLDSEYSFSEQNVDTDISNFALGMHYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPR7</accession>
    <name>B1KPR7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC-C motif domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325936.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3331"/>
    <dbReference type="EnsemblBacteria" id="ACA87600">
        <property type="protein sequence ID" value="ACA87600"/>
        <property type="gene ID" value="Swoo_3331"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3331"/>
    <dbReference type="eggNOG" id="COG3012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172553_0_0_6"/>
    <dbReference type="OMA" id="NRNEPCP"/>
    <dbReference type="OrthoDB" id="1472440at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026368">
        <property type="entry name" value="SWIM_PBPRA1643"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04102">
        <property type="entry name" value="SWIM_PBPRA1643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12383" checksum="A41AE637C37B347F" modified="2008-04-29" version="1">MSDKFFFKGRKTPKPKHESFGYNTKRASKLGTSDNPLNLVVNSEARKAEIEALLSSHELTANIEINPEAKENTLELDGVLNKPQTTRFDKKPNRNEPCPCGSGNKFKKCCG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ72</accession>
    <name>CYOE2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protoheme IX farnesyltransferase 2</fullName>
            <ecNumber evidence="1">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Heme B farnesyltransferase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Heme O synthase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cyoE2</name>
        <name type="ordered locus">Swoo_0429</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="ACA84727" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84727.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ72"/>
    <dbReference type="SMR" id="B1KQ72"/>
    <dbReference type="STRING" id="392500.Swoo_0429"/>
    <dbReference type="EnsemblBacteria" id="ACA84727">
        <property type="protein sequence ID" value="ACA84727"/>
        <property type="gene ID" value="Swoo_0429"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0429"/>
    <dbReference type="eggNOG" id="COG0109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029631_0_0_6"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0350">Heme biosynthesis</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000346018" description="Protoheme IX farnesyltransferase 2">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="289" mass="31112" checksum="B1EDE9D2AE44DEA8" modified="2008-09-02" version="2">MIKPGIIMGNLISVTGGFLLAAKGSVDLTLMLMTILGLSLVVASGCGLNNCIDRDIDAKMQRTRNRVTVTGEISVYSVLVFSLALGLIGFGLLAIFTNKIALLFAVIGYLVYVGIYSLYMKRHSVYGTLIGSFSGAVPPVVGYCAVTGEIDTGAVILLLMFSLWQMPHSYAIAIFRYKDYAAAKIPVLPVAKGMTRAKLHIVLYIAVFSLVSALLPLAGYTGIAFMAVTCATSLWWLGMALKGYQRDINLNQWARQVFGCSIVTITALSIAMAMDFQLVVQTPLLTLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ76</accession>
    <name>B1KQ76_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquinol oxidase subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_0433</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323080.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0433"/>
    <dbReference type="EnsemblBacteria" id="ACA84731">
        <property type="protein sequence ID" value="ACA84731"/>
        <property type="gene ID" value="Swoo_0433"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0433"/>
    <dbReference type="eggNOG" id="COG1622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036876_6_1_6"/>
    <dbReference type="OMA" id="TAMNSFF"/>
    <dbReference type="OrthoDB" id="1654242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04212">
        <property type="entry name" value="CuRO_UO_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010514">
        <property type="entry name" value="COX_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034227">
        <property type="entry name" value="CuRO_UO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006333">
        <property type="entry name" value="Cyt_o_ubiquinol_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06481">
        <property type="entry name" value="COX_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000292">
        <property type="entry name" value="Ubi_od_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01433">
        <property type="entry name" value="CyoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="14">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="13">
        <location>
            <begin position="120"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA84731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="34129" checksum="1989D49C1913E37D" modified="2008-04-29" version="1" precursor="true">MLIRNLSKAALTASVIMMSGCEGGVLDPKGQIGIDEKHLIVVATLLMLIVVIPVIFMTLYFAWKYRDGRDHEIFAPKWAHSKSIEIIVWLVPVVIVIILGVITWGSTHDLDPYKPLEHEAKPITVEVVSLNWKWLFIYPELGIASVNELAFPANVPVNFKITSDTAMNSFFIPQLGSQIYSMAGMATQLHLIANEPGTFDGISANYSGAGFAGMKFKAIATANTQEFDTWVAKVKQQKYKLDRQSYQALAKPSENNPVEYYGEVSQGMFDHIVMQYMYMGDPMPMDKKIDMSSPSGHSSSNHLEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA1</accession>
    <name>B1KQA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323105.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0458"/>
    <dbReference type="EnsemblBacteria" id="ACA84756">
        <property type="protein sequence ID" value="ACA84756"/>
        <property type="gene ID" value="Swoo_0458"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0458"/>
    <dbReference type="eggNOG" id="COG2013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040551_4_1_6"/>
    <dbReference type="OMA" id="AMVYMKG"/>
    <dbReference type="OrthoDB" id="1063432at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="24475" checksum="D7D454DE729086E3" modified="2008-04-29" version="1">MEIELLYRPGNTAAKVTLEEGQTITTESGAMIAMSGNMDITTTTHKKKSGGFLKAAKRMLAGESLFLNHFEPKQGSGELFLGSSLAGDMMTMDLDNESLIVQNSSYMASSEGIDVDMGWQGFKSLFSGESVIWLNLKGQGKILISSFGAIYPVEVDGEYIVDSGHIVAFDETLDFSITKAGKSWWHSYLGGEGLVCKFKGKGTVWCQSHNPSSFGGALSSSLRARKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQF5</accession>
    <name>B1KQF5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0513</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323158.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0513"/>
    <dbReference type="EnsemblBacteria" id="ACA84810">
        <property type="protein sequence ID" value="ACA84810"/>
        <property type="gene ID" value="Swoo_0513"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0513"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_2_6"/>
    <dbReference type="OMA" id="QVGVAPK"/>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="5">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="108" mass="11860" checksum="783D55A3E572D4E9" modified="2008-04-29" version="1">MSDKIVHLSDDSFENDVINSTLPVVVDFWAEWCGPCKMIAPILDDVAEEYEGKVTIAKMNVDQNSVSPAKYGVRGIPTLLIFKNGELASTKVGALSKTQLKEFIDAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQK3</accession>
    <name>B1KQK3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved hypothetical secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324588.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1958"/>
    <dbReference type="EnsemblBacteria" id="ACA86242">
        <property type="protein sequence ID" value="ACA86242"/>
        <property type="gene ID" value="Swoo_1958"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1958"/>
    <dbReference type="eggNOG" id="ENOG5032QUS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117522_0_0_6"/>
    <dbReference type="OMA" id="FLHWGEG"/>
    <dbReference type="OrthoDB" id="1551664at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019545">
        <property type="entry name" value="DM13_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10517">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51549">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM13" evidence="1">
        <location>
            <begin position="53"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="17873" checksum="7880E84EAFCD109B" modified="2008-04-29" version="1" precursor="true">MKKRYLLALLFSHLFVAGGGFIMGMYLLPIMTAPAAPQLSVLESTIESREFSGQFSRERADSDLLHWGEGEVSISADSIAFIGSLAPGPDYRLYLSPKFVDTESGFNRLKPSMVQVGSVNTFDNFIVTIPDDVDPSHYNTLVVWCESFGQFITSGTYETVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQQ9</accession>
    <name>B1KQQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coproporphyrinogen dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.98.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.98.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326000.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3397"/>
    <dbReference type="EnsemblBacteria" id="ACA87665">
        <property type="protein sequence ID" value="ACA87665"/>
        <property type="gene ID" value="Swoo_3397"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3397"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027579_3_1_6"/>
    <dbReference type="OMA" id="HHLMIMM"/>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="46"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="439" mass="49744" checksum="C7C7D89B77AAE929" modified="2008-04-29" version="1">MKDSRLNTRLLLATDSLDWVMNRTIKQSLSLKNATPLSVESDENAIPSKPIETLYIHIPFCHTLCRFCSFHKVKFSEPLAREYFVALRQEIREVIAKGYRFNRVYIGGGTTTILEDELIKTIEMIKGLTPIREVSCESDPIYFKEGNPQLLNGLVDRMSIGVQSFDDKILKASGRFEKFGSGLEQADYVARAIALIPTVNLDMMYGFKTQTPESVHWDLKQTLRLKPDQITTYPLTIGIGKNRKKAGSLAGDPHALWPQFLAVKKALSGRYLMEFPWTFSRNFGQAVENKYVLDGEDCFGVGSGAFGRFGEQFRISSFDIQDYIQLIKQQQSGTCYTKQIESSALLQHHLMIMMGHGRLDNSVFYQHTGKTLWQAFPLEMSYLIGAGAIKKDGSQYVTTEQGQFIGLKMFTGFLSGMDYLREQARDLPLMHQELSAEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQS8</accession>
    <name>B1KQS8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3416</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326019.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3416"/>
    <dbReference type="CAZy" id="CBM20">
        <property type="family name" value="Carbohydrate-Binding Module Family 20"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87684">
        <property type="protein sequence ID" value="ACA87684"/>
        <property type="gene ID" value="Swoo_3416"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3416"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_7_3_6"/>
    <dbReference type="OMA" id="LDIVCNH"/>
    <dbReference type="OrthoDB" id="148706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM_fam20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767569" evidence="6">
        <location>
            <begin position="28"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="7">
        <location>
            <begin position="600"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="703" mass="77696" checksum="7C737B8D6C06288D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQY7</accession>
    <name>B1KQY7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326077.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3477"/>
    <dbReference type="EnsemblBacteria" id="ACA87743">
        <property type="protein sequence ID" value="ACA87743"/>
        <property type="gene ID" value="Swoo_3477"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3477"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_0_1_6"/>
    <dbReference type="OMA" id="CEGQALD"/>
    <dbReference type="OrthoDB" id="1861068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="293" mass="31406" checksum="010312C925715B50" modified="2008-04-29" version="1">MLAQATTQYQQRVDNQLTQVIDAQSVTDSQLLAAMKHGALIGGKRIRPFLVYAIGEMLNVPQEKLDAAAAAIECIHAYSLIHDDLPAMDDDALRRGQPTVHVAFDEATAILAGDALQALAFDILSQPIDGLTPTQNLAMVRALAKASGYSGMCGGQAMDLNATDKQIDLATLTQLHKLKTGALIRCAVELPMIAADLPKDEQALLMTFADAVGLAFQVQDDVIDIISSTEELGKPQGSDCDSNKSTYPKLLGLDGAKATAESLIQDALSALTKLPYNSQLIAEFARFIIERRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR31</accession>
    <name>B1KR31_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323196.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0552"/>
    <dbReference type="EnsemblBacteria" id="ACA84848">
        <property type="protein sequence ID" value="ACA84848"/>
        <property type="gene ID" value="Swoo_0552"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0552"/>
    <dbReference type="eggNOG" id="ENOG5033DRY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_204001_0_0_6"/>
    <dbReference type="OMA" id="WSTNEAT"/>
    <dbReference type="OrthoDB" id="2003947at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021379">
        <property type="entry name" value="DUF3012"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11216">
        <property type="entry name" value="DUF3012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766978" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="66" mass="7240" checksum="A8B7C8761982016A" modified="2008-04-29" version="1" precursor="true">MSLSTKLTKTVSATFSILMASVFVISLSGCAPEVGSEKWCKQMSEKDKGDWSTNEATDYAKHCVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR40</accession>
    <name>B1KR40_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">N-acetyl-beta-glucosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0561</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323205.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0561"/>
    <dbReference type="CAZy" id="GH20">
        <property type="family name" value="Glycoside Hydrolase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84857">
        <property type="protein sequence ID" value="ACA84857"/>
        <property type="gene ID" value="Swoo_0561"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0561"/>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007082_4_1_6"/>
    <dbReference type="OMA" id="HINGDWY"/>
    <dbReference type="OrthoDB" id="727559at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02847">
        <property type="entry name" value="E_set_Chitobiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004866">
        <property type="entry name" value="CHB/HEX_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004867">
        <property type="entry name" value="CHB_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03173">
        <property type="entry name" value="CHB_HEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03174">
        <property type="entry name" value="CHB_HEX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SMART" id="SM01081">
        <property type="entry name" value="CHB_HEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765143" description="Beta-N-acetylhexosaminidase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="CHB_HEX" evidence="8">
        <location>
            <begin position="31"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="853" mass="96516" checksum="D48AC2B18C58C6BC" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRA6</accession>
    <name>B1KRA6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome biogenesis GTPase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2029</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324659.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2029"/>
    <dbReference type="EnsemblBacteria" id="ACA86313">
        <property type="protein sequence ID" value="ACA86313"/>
        <property type="gene ID" value="Swoo_2029"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2029"/>
    <dbReference type="eggNOG" id="COG1161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011106_1_0_6"/>
    <dbReference type="OMA" id="GVLWPKF"/>
    <dbReference type="OrthoDB" id="1083771at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019991">
        <property type="entry name" value="GTP-bd_ribosome_bgen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016478">
        <property type="entry name" value="GTPase_MTG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006230">
        <property type="entry name" value="MG442"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03596">
        <property type="entry name" value="GTPase_YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="4">
        <location>
            <begin position="14"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="276"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="58"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="124"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006230-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="312" mass="35252" checksum="05B25FA18786EF81" modified="2008-04-29" version="1">MAIQWYPGHMHKARKEIEEVMPQVDLVIEVLDARIPYSSENPVVSSLRGDKPCIKLLNKSDLADPETTQRWIEYLEREQGVKAMAITTLQAAQVKKIPDLCRKFVPSRDKIEKDIRTMIMGIPNVGKSTIINTLAGRTIAKTGNEPAVTKVQQRINLRNGIVLSDTPGILWPKVDNEKSSYRLAITGAIKDTAMEYEDVAMFAAEYFLQAYPEAIAERYKLKELPDTDIELLEAIGRKRGALRPGGRIDLHKVSELVLHEFRSGKIGQLSLETPEMAEIEKEEVAILMAKKEAEKQAKEEAEKLKRSGKRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRB9</accession>
    <name>B1KRB9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="4">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2042</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324672.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2042"/>
    <dbReference type="EnsemblBacteria" id="ACA86326">
        <property type="protein sequence ID" value="ACA86326"/>
        <property type="gene ID" value="Swoo_2042"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2042"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_6"/>
    <dbReference type="OMA" id="KMPERDY"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 4" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="16"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="63"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="155"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="26179" checksum="68252987941FC6F1" modified="2008-04-29" version="1">MSVSIDLAGKVALVTGASRGIGRAVAETLVAAGARVVGTATSERGAAAIQEYLGDNGLGLVLNVTDGQSVTDLFAAIKEKEGDVNILVNNAGITRDNLLMRMKDDEWGDIIDTNLTSIFRTSKAVMRPMMKKRHGRIINIGSVVGSMGNPGQTNYCAAKAGLIGFTKSLAKEVASRQITVNAIAPGFIQTDMTDELTEEQQQGIMSQVPMERLGQAQEIANAVLFLASDSAAYITGETLHVNGGMYMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG6</accession>
    <name>B1KRG6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histidine biosynthesis bifunctional protein HisB</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Histidinol-phosphatase</fullName>
                <ecNumber evidence="9">3.1.3.15</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">Imidazoleglycerol-phosphate dehydratase</fullName>
                <shortName evidence="9">IGPD</shortName>
                <ecNumber evidence="9">4.2.1.19</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisB</name>
        <name evidence="10" type="ordered locus">Swoo_2089</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the histidinol-phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="9"/>
    <dbReference type="EC" id="4.2.1.19" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324718.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2089"/>
    <dbReference type="EnsemblBacteria" id="ACA86373">
        <property type="protein sequence ID" value="ACA86373"/>
        <property type="gene ID" value="Swoo_2089"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2089"/>
    <dbReference type="eggNOG" id="COG0131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0241">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044308_0_0_6"/>
    <dbReference type="OMA" id="PEDTFWP"/>
    <dbReference type="OrthoDB" id="1278103at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01022">
        <property type="entry name" value="Bifunc_HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020566">
        <property type="entry name" value="His_synth_bifunc_HisB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005954">
        <property type="entry name" value="HisB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01261">
        <property type="entry name" value="hisB_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Histidinol-phosphatase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Imidazoleglycerol-phosphate dehydratase" evidence="9">
        <location>
            <begin position="167"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="39905" checksum="5FC3ABE4F7C1606A" modified="2008-04-29" version="1">MKQNILFIDRDGTMIEEPITDKQVDSLAKLVFEPQLIPSLLKLQDAGYRLVMVSNQDGLGTPSFPKDDFDAPQNMMMQILESQGVVFDEVLLCPHFDDENCSCRKPKLGLVKEYLTSGKVDFTRSAVIGDRHTDMGLADAMGVKGLQYNRESLNWNTITEQLLTRERVASVTRTTKETDIRVTIDLDSQDKGTIETGIGFFDHMLDQIATHGSFKMDVTVDGDLEIDDHHSVEDTALAIGDALRQALGDKRGIARFGDAFEQAIPMDEASASCLLDLSGRPFIKFKGEFERELVGSMATEMVPHFFRSFADGLRCTLHLSTEGDNDHHKVESLFKVLGRTLRQAVKVEGDSLPSSKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH1</accession>
    <name>B1KRH1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324723.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2094"/>
    <dbReference type="EnsemblBacteria" id="ACA86378">
        <property type="protein sequence ID" value="ACA86378"/>
        <property type="gene ID" value="Swoo_2094"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2094"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_5_3_6"/>
    <dbReference type="OMA" id="TTNAWGM"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="149"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="309" mass="34269" checksum="7A624068F1521291" modified="2008-04-29" version="1">MTAVLYGVMIFVWGFSWIAIKWQQGEVPTEVSIFYRFAIAAALMFALGIVFKKLQATNRRQHLFFALQGLCLFSINFMAFYSATHYIASGLTAVVMSTAPLFNALHGKLIFNTPIKRNFGLGVFVGLSGILLLFGGDLIDAQWSPELLYGLLFSLLGTWCFSIGNMISIYNSQSQIQPYTATSYAMAYGCVVLLIIITLKGFSLEVETSTRYLVSLAYLAIPASVIGFTVYLMLVDRLGANQAAYLLLITPIVALITSSFLEGYRWTLYSSLGLVCVISGNLITQIKPSILAYLYGFVRRERRVDKISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK4</accession>
    <name>B1KRK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326102.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3505"/>
    <dbReference type="EnsemblBacteria" id="ACA87769">
        <property type="protein sequence ID" value="ACA87769"/>
        <property type="gene ID" value="Swoo_3505"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3505"/>
    <dbReference type="eggNOG" id="ENOG502Z95H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_780526_0_0_6"/>
    <dbReference type="OMA" id="RFMNQVE"/>
    <dbReference type="OrthoDB" id="1039865at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021433">
        <property type="entry name" value="DUF3083"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11281">
        <property type="entry name" value="DUF3083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="356" mass="41002" checksum="94279CF923DBA5E8" modified="2008-04-29" version="1">MSLNHQQKVYIPKAARTNQYIAAEIKVTDALLAHYPDLKTCYQTVSRSIFNLADQEELSNIHVITNDKLPVVRFHTEAYCFQTAEQIILFYNPAYHEAQNLITDDNYRARKIRIVFLATGDEIRSNSASFHAKVQSFLTKLMPQLPENELTVKIRDHQHLSYDFFAKAKGNKESYGFKLRAIGPRYKARNCPLPEEHSSLSYVTVKLPLGRRLKQSILPEHTNDFTPLYQKLEDAFLHATSAKQLKQVAMVANGLTPLVRNSKYDQVDGTDEVQMIGFDPNQEEQQFVRHWDGSQLVETVSFTIVAGKKDYKDAGFGRFMNQVEDALKKFTSELELDRSHEDLIVRFHQHISYQNS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX5</accession>
    <name>RECF_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recF</name>
        <name type="ordered locus">Swoo_0003</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322653.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCX5"/>
    <dbReference type="SMR" id="B1KCX5"/>
    <dbReference type="STRING" id="392500.Swoo_0003"/>
    <dbReference type="EnsemblBacteria" id="ACA84304">
        <property type="protein sequence ID" value="ACA84304"/>
        <property type="gene ID" value="Swoo_0003"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0003"/>
    <dbReference type="eggNOG" id="COG1195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040267_0_0_6"/>
    <dbReference type="OMA" id="GESWSYA"/>
    <dbReference type="OrthoDB" id="891841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018078">
        <property type="entry name" value="DNA-binding_RecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00617">
        <property type="entry name" value="RECF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00618">
        <property type="entry name" value="RECF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <feature type="chain" id="PRO_1000121155" description="DNA replication and repair protein RecF">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <sequence length="365" mass="41259" checksum="F3F6D2C8601BB894" modified="2008-04-29" version="1">MSLTRLHIETFRNISSAQLHPSDGLNLIYGQNGSGKTSVLEAIYFLGMGRSFRSHLSQRVIQHQDDKLTLFANLSLGEQESKIGLRRFRSGETEVKINGDKIKRLSTLAETLPIQVITPESFSLLFEGPKSRRQFIDWGAFHSDKSFHSAWANVKRILKQRNQLLKNQVSYSQIQFWDKELVRYSELVTLIRKEYVDSLNEQLKGIIVEFLPQVEVKVSFTRGWDSKTDFGQLLETQYLRDVAAGNTGSGPHKADLRLRVGTLPVQDALSRGQLKLLVCALRIAQGKLLKQQTDKNSIYLVDDLPSELDAKHRQLLLQQLMDTGAQIFVTAIDPAAIVDSLTTPPSKMFHVEQGCVTVIDKPTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD40</accession>
    <name>B1KD40_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9 11">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="3 9 11">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_3611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 11">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="3 9 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326208.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3611"/>
    <dbReference type="EnsemblBacteria" id="ACA87875">
        <property type="protein sequence ID" value="ACA87875"/>
        <property type="gene ID" value="Swoo_3611"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3611"/>
    <dbReference type="eggNOG" id="COG1477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044403_0_0_6"/>
    <dbReference type="OMA" id="MGTYYSI"/>
    <dbReference type="OrthoDB" id="2021063at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="338" mass="37261" checksum="6FB323F3D1E49DDA" modified="2008-04-29" version="1" precursor="true">MQKTAVKWLAFIGLAFFISACSKPVEIISLSGNTMGTTYHIKVVPNAQLPEPNLLQAEIDLALEKVNDQMSTYRPNSELSRFNSSDFEETVTVSADTATVIKEAIHLFEVTDGALDITLGPLVNLWGFGPDKRPTQIPTSEMIDEAKARTGIQYLSVDGNKLSKTKSDLYVDLSSIAKGFGVDIVAAILDKYHVSGYLVEVGGELSVFGHKIDGSPWRVAIERPDMDDREIQQVIAPGDMAIATSGDYRNYYEEDGHQFSHLIDPRTGYPIDHRLASVTVLHKQSMVADGYATAMMVLGTEKSLELAKQQNLAIMLIEKQDNGFKIFYSDGFKPFVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD78</accession>
    <name>B1KD78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3651"/>
    <dbReference type="EnsemblBacteria" id="ACA87913">
        <property type="protein sequence ID" value="ACA87913"/>
        <property type="gene ID" value="Swoo_3651"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3651"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_10_2_6"/>
    <dbReference type="OMA" id="RYRRIYC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="17"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="483" mass="53869" checksum="FF9C6881EF8B7607" modified="2008-04-29" version="1">MGLMLGSSAIAAQQTPPNVVIVLADDMGFGHVAMNLDLATADSYNPQNLKRDSQRHKPELARSYAKKATPTLTQLANEGVRFTNAYVPSPLCGPSRAALMTGRYPQRFGIYNNADVKAAGLPVEENVLANNFRKAGYRTGAVGKWHLTKGEKKASYTLAQHPLDRGFDFFFGFDRSGTPYYDSKILELNRKPVKAEGYLTDQLTNHAIDFINQDKSKPFFLYMAYNAVHGPLNKAAPKEYQAPFNSGDRYLDYFYSYLYALDQGVAKIIKQLDSNGQLDNTIIMFLSDNGAPGGKPFPLPANAPFTGYKGQVWQGGTRVPVVIWGPKALVNGGRVDDAVISSMDLIPTALAAAGVDLSDNLDGNNLLPKLKRVEEDERQLFWASQLSHHWGFIRDAKGKKIDDKSTAEPAWAVRSGEWMLRYWADSKKTELFNVSTDHAEHHDIANKHPQVVKQLTADYKVWFDTLAKPAGWDKRYWEQLEVK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD83</accession>
    <name>GLAA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName>Alpha-1,3-galactosidase A</fullName>
            <ecNumber>3.2.1.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Exo-alpha-galactosidase A</fullName>
            <ecNumber>3.2.1.22</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">glaA</name>
        <name type="ordered locus">Swoo_3656</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Alpha-galactosidase that specifically removes branched alpha-1,3-linked galactose residues present in blood group B antigens. Has no activity toward linear alpha-1,3-linked galactose residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>Hydrolysis of terminal, non-reducing branched (1-&gt;3)-alpha-D-galactosidic residues, producing free D-galactose.</text>
            <dbReference type="EC" id="3.2.1.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 110 family. A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.n1"/>
    <dbReference type="EC" id="3.2.1.22"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326251.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KD83"/>
    <dbReference type="SMR" id="B1KD83"/>
    <dbReference type="STRING" id="392500.Swoo_3656"/>
    <dbReference type="CAZy" id="GH110">
        <property type="family name" value="Glycoside Hydrolase Family 110"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87918">
        <property type="protein sequence ID" value="ACA87918"/>
        <property type="gene ID" value="Swoo_3656"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3656"/>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017693_0_0_6"/>
    <dbReference type="OrthoDB" id="1217730at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052692">
        <property type="term" value="F:raffinose alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0326">Glycosidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0449">Lipoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0564">Palmitate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5000316297" description="Alpha-1,3-galactosidase A">
        <location>
            <begin position="22"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="repeat" description="PbH1 1">
        <location>
            <begin position="262"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="PbH1 2">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="PbH1 3">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="PbH1 4">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="repeat" description="PbH1 5">
        <location>
            <begin position="481"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="N-palmitoyl cysteine" evidence="2">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="S-diacylglycerol cysteine" evidence="2">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="608" mass="68216" checksum="6691BAA70326DB2A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDE5</accession>
    <name>B1KDE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323293.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84946">
        <property type="protein sequence ID" value="ACA84946"/>
        <property type="gene ID" value="Swoo_0650"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0650"/>
    <dbReference type="eggNOG" id="ENOG50308IK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1795169_0_0_6"/>
    <dbReference type="OMA" id="IVKVNLH"/>
    <dbReference type="OrthoDB" id="1735535at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16331" checksum="0C2EC945C0A78274" modified="2008-04-29" version="1">MYNTVKTPIWYGELRTARGNAIVIHDKQFPEASAGRIYLYNTQRDSIIEYAEEIVQHNLHDLDKASAKAAAETYGAAWNSARSEFMGKHEGWVEAISSKHKPLIKKEAQKDLDSNKTPDDEIDLDDGSESQDREFADGWSGGLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF7</accession>
    <name>B1KDF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0662</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323305.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0662"/>
    <dbReference type="EnsemblBacteria" id="ACA84958">
        <property type="protein sequence ID" value="ACA84958"/>
        <property type="gene ID" value="Swoo_0662"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0662"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_3_5_6"/>
    <dbReference type="OMA" id="VLCRDFG"/>
    <dbReference type="OrthoDB" id="1596937at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="25"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="139"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="211" mass="23773" checksum="2D3EBB4A07DA9588" modified="2008-04-29" version="1">MALIGKPKPDPTLEWFLSHCHIHKYPAKSTLIHAGEESDTLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEQAERTAWVRAKQPCEIAEISYKKFKQLIQVNPEILMKLSSQMAYRLHSTSQKVGDLAFLDVAGRIAQTLLHLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLIQAHGKTIVVYGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDI8</accession>
    <name>B1KDI8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323336.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84989">
        <property type="protein sequence ID" value="ACA84989"/>
        <property type="gene ID" value="Swoo_0694"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0694"/>
    <dbReference type="eggNOG" id="ENOG5033938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_645416_0_0_6"/>
    <dbReference type="OrthoDB" id="1146930at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="425" mass="47504" checksum="71957AA86831F97E" modified="2008-04-29" version="1">MRVLVTVMSLIWMLTYDLNAYAGSLSAEQVNGVYDLAKPERSAAGQTQELLIQLGEHQGKTVIATAGCERCPPAIYSLMKQESSELQRAVFFNSMGVYLISYDDNTLVSVMADGLLGKKVWQKIAYINVYRKRGTPGIELAAAKTFVISESKRMITGEGVEKVAVTGGSGHYYSAARYQINGTSYDQFALTVEAEKAVLLEGDKCRSCTSDRFIYEPELSLAIGKPVYEMGHMGRFIIEESKGVFLYAKAKLGKALWGKNSHFNLFAQDPIYVRTISSDKNMQQEIDSQLASYAQLAKNAVDEHYRQQDAERTASNELPMQGLKDEKLQQQVLNAAKQRADKESWNESILNAYIRGNDWTILRNKLTGIQTGRYIAGVIVMQREDGLCSYQSVHFAQQYNGADYQQAYVYSIDSGQEKLDCSKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ2</accession>
    <name>B1KDJ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323340.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0698"/>
    <dbReference type="EnsemblBacteria" id="ACA84993">
        <property type="protein sequence ID" value="ACA84993"/>
        <property type="gene ID" value="Swoo_0698"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0698"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048587_0_0_6"/>
    <dbReference type="OMA" id="EFYDYYR"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764311" evidence="1">
        <location>
            <begin position="26"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S15" evidence="2">
        <location>
            <begin position="43"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="345" mass="37918" checksum="AF72A213609CC1BD" modified="2008-04-29" version="1" precursor="true">MNKTKISILATVLASVMSTPFSVSAEESFNTGKNAVNFLSENVRISGNLYLPDNYSANGSFPAIVVITPASGVKEQTAGIYAKKLADKGYVTLAFDHRSYGESGGMPRGMENAPMKVEDIKNAISFIRTVAGVDIERIGELGLCSGAGYSLQTAQMDGRIDSVATVSGFVDFIDYGLSGATQYQNGLSGDKIEQFQTQIQWASEARQRYFETGEVMYVDGIPPKSERLGIFWDRAADYYLNPERGGAVATYSPMRAAMSLDTRYFFNPTEHMELMRGKPFLAIVGTEALSAQFSEVAVERSKKAGGEAELFKVKGAQHFDLYDKHKYVNQAVDKLDSFYRTTLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL6</accession>
    <name>B1KDL6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paraquat-inducible protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324758.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2129"/>
    <dbReference type="EnsemblBacteria" id="ACA86413">
        <property type="protein sequence ID" value="ACA86413"/>
        <property type="gene ID" value="Swoo_2129"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2129"/>
    <dbReference type="eggNOG" id="COG2995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041903_1_0_6"/>
    <dbReference type="OMA" id="WGMLEVY"/>
    <dbReference type="OrthoDB" id="1604315at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007498">
        <property type="entry name" value="PqiA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04403">
        <property type="entry name" value="PqiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="208" mass="23455" checksum="769B01AEE430D982" modified="2008-04-29" version="1">MERDCIDDCVTLCRSCDLVVTKRALPSGVRALCPRCHTALYDTPYCSINGMLALCITALIFFTPANFLPILELHFLGSVRTATIAEGAIAVAHQGYWIVGISVMLTAVIAPGVLILSILSQILIIKYRLHSPFFRDVLKRLLKYQDILSQLTMLEIYLISILVSVFNLSDFADIFLGMGTFCFSMLFIVTLFLQREYNLEHMWSMLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDT2</accession>
    <name>B1KDT2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2197</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324823.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2197"/>
    <dbReference type="EnsemblBacteria" id="ACA86479">
        <property type="protein sequence ID" value="ACA86479"/>
        <property type="gene ID" value="Swoo_2197"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2197"/>
    <dbReference type="eggNOG" id="COG2176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047806_7_1_6"/>
    <dbReference type="OMA" id="FDQKFWD"/>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="8"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="205" mass="22772" checksum="9369BF31F4D2FF45" modified="2008-04-29" version="1">MLNPASNSAIVLDFETTGLSPNQGDRAIEIGAVKLEDGVVVDTFQALMNPGFRITSFIESYTGITNQMLSTAAPCEVVMDRFADFIHGSNLVAHNASFDQRFLDAELSLINRHYTGEFACSMLIARRIYQEAPNHKLGGLVAFRQIENDGVFHRALADSEMTAKLWLTMIEDIQTRYSITTPSFKLMQKIAKKPKSSVNAFLCTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE19</accession>
    <name>B1KE19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0710</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323352.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0710"/>
    <dbReference type="EnsemblBacteria" id="ACA85005">
        <property type="protein sequence ID" value="ACA85005"/>
        <property type="gene ID" value="Swoo_0710"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0710"/>
    <dbReference type="eggNOG" id="COG4988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_6"/>
    <dbReference type="OMA" id="FPLNWAA"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042883">
        <property type="term" value="P:cysteine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014216">
        <property type="entry name" value="ABC_transptr_CydD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02857">
        <property type="entry name" value="CydD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="26"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="361"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="394"/>
            <end position="401"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="607" mass="66314" checksum="7D0309D8FC0AA372" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE81</accession>
    <name>B1KE81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323414.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85067">
        <property type="protein sequence ID" value="ACA85067"/>
        <property type="gene ID" value="Swoo_0772"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0772"/>
    <dbReference type="eggNOG" id="ENOG5033CWW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_186680_0_0_6"/>
    <dbReference type="OMA" id="QLLFVRQ"/>
    <dbReference type="OrthoDB" id="1956106at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="10277" checksum="3F2FDB1344E4BC02" modified="2008-04-29" version="1">MQVAAINSTESFDDRRLEQPNIDQHWHRLSTAQRFAFYTLAKLGYQLLFVRQSSHEKTAVARQDDKLVTIDSEGDINFNPTLILRENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEG3</accession>
    <name>B1KEG3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2260"/>
    <dbReference type="EnsemblBacteria" id="ACA86541">
        <property type="protein sequence ID" value="ACA86541"/>
        <property type="gene ID" value="Swoo_2260"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2260"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="HFMEEAQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022467">
        <property type="entry name" value="ABC_transprt_ATP-bd_su_PQQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03864">
        <property type="entry name" value="PQQ_ABC_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="26874" checksum="45CFB9F51B3C3066" modified="2008-04-29" version="1">MVRDLSYGYGNKEVLKQLNFSLGTGFNLLLGPNGAGKSTLFSLLTGLFNRGQGEIELCGLDLVQHRRAALSKLGVVFQQSTLDLDLSVKQNLIYQGSLHGLSAMDSLNRVTPILEKLELSQRLNERVRVLNGGHKRRLEIARALMHRPKVILLDEPTVGLDTDSRLLIIEHVRRLAKEMDICVLWATHLMDEANSDDELLLLDRGQICAAGQCQKLYTKHGVNDLFELYRKLTQQVELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEK0</accession>
    <name>B1KEK0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protease 4</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Endopeptidase IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Signal peptide peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2299</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S49 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324920.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2299"/>
    <dbReference type="EnsemblBacteria" id="ACA86578">
        <property type="protein sequence ID" value="ACA86578"/>
        <property type="gene ID" value="Swoo_2299"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2299"/>
    <dbReference type="eggNOG" id="COG0616">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008856_1_1_6"/>
    <dbReference type="OMA" id="DPKGQYL"/>
    <dbReference type="OrthoDB" id="1318587at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004634">
        <property type="entry name" value="Pept_S49_pIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004635">
        <property type="entry name" value="Pept_S49_SppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001217">
        <property type="entry name" value="Protease_4_SppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00705">
        <property type="entry name" value="SppA_67K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00706">
        <property type="entry name" value="SppA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="6">
        <location>
            <begin position="136"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="6">
        <location>
            <begin position="391"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001217-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="613" mass="67093" checksum="3AC7AA1BC16425C5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET1</accession>
    <name>B1KET1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326426.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3837"/>
    <dbReference type="EnsemblBacteria" id="ACA88096">
        <property type="protein sequence ID" value="ACA88096"/>
        <property type="gene ID" value="Swoo_3837"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3837"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022247_0_0_6"/>
    <dbReference type="OMA" id="SNNEVFP"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033856">
        <property type="entry name" value="Trp_halogen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011396">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="524" mass="59143" checksum="EA958419A0613454" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX7</accession>
    <name>B1KEX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323475.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85128">
        <property type="protein sequence ID" value="ACA85128"/>
        <property type="gene ID" value="Swoo_0833"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0833"/>
    <dbReference type="eggNOG" id="ENOG502ZKXF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103735_0_0_6"/>
    <dbReference type="OMA" id="PIPNAWL"/>
    <dbReference type="OrthoDB" id="1346329at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="27002" checksum="23DB1D18BC03BEC0" modified="2008-04-29" version="1">MGALLCNRVAAQRFQRGLSGLKVLLIILITILLTMGITIFIIRTYVFPSELTPVVLNAKEESKLDKKLSQLGWQADTSSTSKASSNGQGSKESIAKERVSEVDELMPEPYRELDGDRQVTFSEKEVNAMIGNNPDFARRVAIDFSDELASAKILVPIPEDFPIMPGQILRVNAGIDIHLDDTRRPVVALVGVSLMGVPIPNAWLGNMKNVNLVGEFGDSGFWNSFADGVEDLQVRDGELYIKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC9</accession>
    <name>B1KFC9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325012.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2391"/>
    <dbReference type="EnsemblBacteria" id="ACA86670">
        <property type="protein sequence ID" value="ACA86670"/>
        <property type="gene ID" value="Swoo_2391"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2391"/>
    <dbReference type="eggNOG" id="ENOG5032S1T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2422016_0_0_6"/>
    <dbReference type="OMA" id="RVNMTYY"/>
    <dbReference type="OrthoDB" id="1827659at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="91" mass="10766" checksum="CC6AF202E1797CCC" modified="2008-04-29" version="1">MKSNLDKMLASHNKLVHSEGVKIVSHTQREVEEWVQHTVMIEGCDAPFKFRRPKKFKCLKGNRVNMTYYPEQEKVAGFEIEVMKVVRIKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFR2</accession>
    <name>B1KFR2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0935</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323575.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0935"/>
    <dbReference type="EnsemblBacteria" id="ACA85228">
        <property type="protein sequence ID" value="ACA85228"/>
        <property type="gene ID" value="Swoo_0935"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0935"/>
    <dbReference type="eggNOG" id="COG0578">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015740_5_0_6"/>
    <dbReference type="OMA" id="TFCGVRV"/>
    <dbReference type="OrthoDB" id="360065at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DAO" evidence="7">
        <location>
            <begin position="5"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="391" mass="43616" checksum="7ED3686163CBB834" modified="2008-04-29" version="1">MDRFDLVIIGGGINGAGIAQCASAAGFSVLLLEKGEIAEQTSANSSKLIHGGLRYLESGQLSLVRKSLSERRALLKLAPNLVKPIPFYIPVYENSQRSQWAIRAGLSAYALLSELDPLGQFKSLPAVQWPNIKGLKLQGLEAVFQYWDAQTDDKALTKSVVRSAVELGAKVLQGAECDALVHRPDHCEVSYLYQDERCKVTASCVVNATGPWVNKLIGCVTPPMAKEEVELIQGSHLLLDIPSPDGILYLESCFDERVVFVMPWEGKTLLGTTETTLASLDEKPQPTREESYYLLGIYRHYFPESGDIETLEAKIYDTFCGVRVLPKQAGQAFERSRELWLQSRESHPRFLTLYGGKLTTFRSTAKEVTHWLHERLGERVEIADIDRLPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY9</accession>
    <name>B1KFY9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DsbD_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325038.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2418"/>
    <dbReference type="EnsemblBacteria" id="ACA86696">
        <property type="protein sequence ID" value="ACA86696"/>
        <property type="gene ID" value="Swoo_2418"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2418"/>
    <dbReference type="eggNOG" id="COG2836">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032635_0_0_6"/>
    <dbReference type="OMA" id="GRISTYM"/>
    <dbReference type="OrthoDB" id="1818448at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039447">
        <property type="entry name" value="UreH-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13386">
        <property type="entry name" value="DsbD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD_2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="24389" checksum="22D3A12AFAC1F854" modified="2008-04-29" version="1">MIDYNITGAFLVGLMGAGHCIGMCGGLVGAFSSQLATTPGQNLLASKLKFLLTYNLGRILSYSLAGALVGGSASALGMLFDIDLYLITLRVIAGVMMIITGLYIAQIWSGVVQIERLGKFIWRFLSPLANRVVPIRTLRQAFVGGVLWGWLPCGLVYSTLTWAVASHSAQQGALIMLAFGLGTLPALLSAGAAANMLGQWVQKRAVRVVSGLILVLFGLQTLYIAIAQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG46</accession>
    <name>B1KG46_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfur relay protein TusB/DsrH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325095.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2476"/>
    <dbReference type="EnsemblBacteria" id="ACA86753">
        <property type="protein sequence ID" value="ACA86753"/>
        <property type="gene ID" value="Swoo_2476"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2476"/>
    <dbReference type="eggNOG" id="COG2168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166087_4_1_6"/>
    <dbReference type="OMA" id="MILHLIQ"/>
    <dbReference type="OrthoDB" id="1995110at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007215">
        <property type="entry name" value="Sulphur_relay_TusB/DsrH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37526">
        <property type="entry name" value="PTHR37526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04077">
        <property type="entry name" value="DsrH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03011">
        <property type="entry name" value="sulf_tusB_dsrH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="93" mass="10719" checksum="05F6F81A480A0CFF" modified="2008-04-29" version="1">MILHKIQTSPAQDNALSTCLRYIDKQDTLLLSGNAVNALLLTCWQEKLSQITVLVLKEDIEARGLNERLNQYSSISYEQFVQETLRHEKVISW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG59</accession>
    <name>RL35_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmI</name>
        <name type="ordered locus">Swoo_2489</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_011496149.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG59"/>
    <dbReference type="SMR" id="B1KG59"/>
    <dbReference type="STRING" id="392500.Swoo_2489"/>
    <dbReference type="EnsemblBacteria" id="ACA86766">
        <property type="protein sequence ID" value="ACA86766"/>
        <property type="gene ID" value="Swoo_2489"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2489"/>
    <dbReference type="eggNOG" id="COG0291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169643_1_1_6"/>
    <dbReference type="OMA" id="PKIKTHR"/>
    <dbReference type="OrthoDB" id="2046660at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_L35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000127408" description="50S ribosomal protein L35">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <sequence length="64" mass="7383" checksum="7E181AF6CFB98C16" modified="2008-04-29" version="1">MPKMKTDKGVAKRFKKTANGFKRKQAHLRHILTKKSTKRKRHLRAKCLVAKSDVPAIARQLPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC6</accession>
    <name>B1KGC6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein ExbD/TolR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4007</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326592.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4007"/>
    <dbReference type="EnsemblBacteria" id="ACA88263">
        <property type="protein sequence ID" value="ACA88263"/>
        <property type="gene ID" value="Swoo_4007"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4007"/>
    <dbReference type="eggNOG" id="COG0848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085305_5_1_6"/>
    <dbReference type="OMA" id="MVFLMLT"/>
    <dbReference type="OrthoDB" id="1537812at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15319" checksum="84695F517D04A4B9" modified="2008-04-29" version="1">MIEVKHEGNNTISGLDLTPLIDIIFIVLVFLLLTANTQLLSLPVDVPTESSAELTPIDQVENITINVLATKPHWALDGIPFEQFTEFEHAFIKQYQQQSEAKVIIAADKTAPVQPLMALLSLLQRQQITNTQILMEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGD5</accession>
    <name>B1KGD5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III restriction protein res subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326601.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4016"/>
    <dbReference type="EnsemblBacteria" id="ACA88272">
        <property type="protein sequence ID" value="ACA88272"/>
        <property type="gene ID" value="Swoo_4016"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4016"/>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020861_0_0_6"/>
    <dbReference type="OMA" id="HLKKQWA"/>
    <dbReference type="OrthoDB" id="458022at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="16"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="469" mass="53139" checksum="5B3EBD0E1FBDF9A9" modified="2008-04-29" version="1">MHLRQWQLECLNRALEHYNAKHRHFLCLATPGAGKTIMAAEVAAQLLEQDLVDFVLCFSPSVNISQGIKHTFLKRLGCRFDGVIGAVGCSYTYQSLLSFKDDFWLLLKQNRVLVVFDEIHHCAGSTLEDANAWGEEILLNIQNQAEYTLALTGTPWRSDQAPIVLSRYIDPEKQIQCDYVYGLRQAVADGVCRNPKIVLIDNAKLSVTNEGNQTKIFNCLDELFKGSSIQYQAVIKNSEAIRHVLTLATRRLQSIKQHNPNAAGLIVASSLEHAAYILNILKTEYAQTAEIVTYKEDQPSNKINEFRSSNINWIVSVGMISEGTDIPRLQVCCHLSRVKTELYFRQVLGRVLRINKTKNQDAWLYTFAEPKLVEFANRLAEEIPDVPVVFREFGDSVFSIDESKAETIKRDNFTLERNTFSFDSPQMEGSKQSFSTSLQNQKDSRDKCSSLEMLGGFREKVVSTFNSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG2</accession>
    <name>B1KGG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0997</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323637.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0997"/>
    <dbReference type="EnsemblBacteria" id="ACA85290">
        <property type="protein sequence ID" value="ACA85290"/>
        <property type="gene ID" value="Swoo_0997"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0997"/>
    <dbReference type="eggNOG" id="COG1178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021838_0_2_6"/>
    <dbReference type="OMA" id="QAFWRVA"/>
    <dbReference type="OrthoDB" id="1783638at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="467"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="51"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="329"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="543" mass="60212" checksum="10EFD168A948C436" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGQ3</accession>
    <name>B1KGQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2495</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325113.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2495"/>
    <dbReference type="EnsemblBacteria" id="ACA86772">
        <property type="protein sequence ID" value="ACA86772"/>
        <property type="gene ID" value="Swoo_2495"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2495"/>
    <dbReference type="eggNOG" id="COG0307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_0_1_6"/>
    <dbReference type="OMA" id="HILSGHV"/>
    <dbReference type="OrthoDB" id="1276859at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="204" mass="22329" checksum="641A413B33023FF2" modified="2008-04-29" version="1">MFTGIVQATCEVVAINKKDGLNTLEIAMKSDLREGLITGASVANNGVCLTVTRIADDRVFFDVMEETLSVTNLSNLQLGSKVNIERSLTFGSEIGGHILSGHIHTQARVLEVSHTEAHFDIKLEVDPKWMNYILYKGFVGVNGCSLTVGEVTETSFMLHLIPETLKLTNLDIIKAGETLNIEIDSQTQAIVDTVERVLAKRANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS7</accession>
    <name>B1KGS7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sigma54 specific transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325137.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2519"/>
    <dbReference type="EnsemblBacteria" id="ACA86796">
        <property type="protein sequence ID" value="ACA86796"/>
        <property type="gene ID" value="Swoo_2519"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2519"/>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_95_4_6"/>
    <dbReference type="OMA" id="NIIERCC"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="200"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="517" mass="58135" checksum="C160639F757A5B0E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU6</accession>
    <name>B1KGU6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgl</name>
        <name evidence="9" type="ordered locus">Swoo_2538</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2538"/>
    <dbReference type="EnsemblBacteria" id="ACA86815">
        <property type="protein sequence ID" value="ACA86815"/>
        <property type="gene ID" value="Swoo_2538"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2538"/>
    <dbReference type="eggNOG" id="COG0363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053947_2_1_6"/>
    <dbReference type="OMA" id="YQLFEFE"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="13"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="233" mass="25904" checksum="529CB80D0A557C9A" modified="2008-04-29" version="1">MMIKESVFKSFDNKEALENQLAERIAKQLQEAVDSRGKASLIVSGGSTPLKLFQLLSNKPIEWSDVYITLADERWVDGDSDDSNEKLVRAHLLQNKAANAKFRGLKNMFSTPEEGCDMAIEQLSHFPRPFDVVVLGMGNDGHTCSWFPCSKEIEQALSTDKLCIAVNPGAAPNPRLSLSKTAILASRQIYLHIVGEQKLAVYRQALESQDANSMPIRAVLDQHKTPVDVYWSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGW4</accession>
    <name>B1KGW4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ion-translocating oxidoreductase complex subunit A</fullName>
            <ecNumber evidence="9">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Rnf electron transport complex subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnfA</name>
        <name evidence="10" type="ordered locus">Swoo_2556</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325174.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2556"/>
    <dbReference type="EnsemblBacteria" id="ACA86833">
        <property type="protein sequence ID" value="ACA86833"/>
        <property type="gene ID" value="Swoo_2556"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2556"/>
    <dbReference type="eggNOG" id="COG4657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095255_1_0_6"/>
    <dbReference type="OMA" id="CPFFGVS"/>
    <dbReference type="OrthoDB" id="1814639at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00459">
        <property type="entry name" value="RsxA_RnfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011293">
        <property type="entry name" value="Ion_transpt_RnfA/RsxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01943">
        <property type="entry name" value="rnfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="192" mass="20628" checksum="73F0EAE30B31A5A0" modified="2008-04-29" version="1">MSEYLLLLVSTVLVNNFVLVKFLGLCPFMGVSSKLESAIGMSMATTFVLTLASILSYLVNQYLLLPFELGYLRTMSFILVIAVVVQFTEMVVQKTSASLYRALGIYLPLITTNCAVLGVALLNINEKHGFVESAIYGFGAAVGFSLVLILFSAMRERLAAADVPLPFKGGAIAMITAGLMSLAFMGFTGLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX7</accession>
    <name>B1KGX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325186.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2569"/>
    <dbReference type="EnsemblBacteria" id="ACA86846">
        <property type="protein sequence ID" value="ACA86846"/>
        <property type="gene ID" value="Swoo_2569"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2569"/>
    <dbReference type="eggNOG" id="ENOG5033E5M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1712033_0_0_6"/>
    <dbReference type="OMA" id="FISAQAD"/>
    <dbReference type="OrthoDB" id="1997247at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764458" evidence="1">
        <location>
            <begin position="24"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="15488" checksum="5DE3C77103CB9DC0" modified="2008-04-29" version="1" precursor="true">MKNNILLSTLIASTFFISAQADAAQATGTANFNLVYPISVTETAVMEFGDVSILADGNCTLGYADNTSGTACVAGGNAALSGEFTIAADNTTVNIALSAADSASVPGVTFTPSVSSNTLTVTGNSAVLKVGGSLDIVAASATAGAKNLTYTVDVTY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX9</accession>
    <name>RUVB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Holliday junction ATP-dependent DNA helicase RuvB</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ruvB</name>
        <name type="ordered locus">Swoo_2571</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with RuvA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RuvB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325188.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KGX9"/>
    <dbReference type="SMR" id="B1KGX9"/>
    <dbReference type="STRING" id="392500.Swoo_2571"/>
    <dbReference type="EnsemblBacteria" id="ACA86848">
        <property type="protein sequence ID" value="ACA86848"/>
        <property type="gene ID" value="Swoo_2571"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2571"/>
    <dbReference type="eggNOG" id="COG2255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055599_1_0_6"/>
    <dbReference type="OMA" id="IHRMSRP"/>
    <dbReference type="OrthoDB" id="874197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00016">
        <property type="entry name" value="DNA_helic_RuvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041445">
        <property type="entry name" value="AAA_lid_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004605">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008823">
        <property type="entry name" value="RuvB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42848">
        <property type="entry name" value="PTHR42848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17864">
        <property type="entry name" value="AAA_lid_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05491">
        <property type="entry name" value="RuvB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00635">
        <property type="entry name" value="ruvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <feature type="chain" id="PRO_1000089677" description="Holliday junction ATP-dependent DNA helicase RuvB">
        <location>
            <begin position="1"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00016"/>
        </source>
    </evidence>
    <sequence length="338" mass="37683" checksum="CA07FC0E9913CBA9" modified="2008-04-29" version="1">MIEADRLIHAEPQGIEERDEQIDRAMRPKMLDEYTGQDDSRAQLKIFIQAAQNRDEALDHMLIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEPGDVLFIDEIHRLSSVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVTRSANVLELPIDEAGAIELARRSRGTPRIANRLLRRVRDFAEVKHDGEITKQVAELALDMLDIDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRIATDRAYRHFDIIQPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH24</accession>
    <name>B1KH24_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="5 8">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="5 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4080"/>
    <dbReference type="EnsemblBacteria" id="ACA88336">
        <property type="protein sequence ID" value="ACA88336"/>
        <property type="gene ID" value="Swoo_4080"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4080"/>
    <dbReference type="eggNOG" id="COG2109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088595_0_0_6"/>
    <dbReference type="OMA" id="HAMGEGF"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR015617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="216" mass="23998" checksum="7D5453D8F1B5CC9B" modified="2008-04-29" version="1">MTENNGTSNMTDKSEMTQEERKAQRHKERQQRVKETVDAKIAAAQEEKGILLVLTGNGKGKSTSGFGTIARSVGHGKKAAVVQFIKGNWDCGERTLLEGAGVDFHVMGTGFTWETQDREKDTQAAESAWAAAEKLLKDETIDCLMLDELTYMISYHYLDVERVVEALKNRPKMQHVIVTGRACHRAIVELADTVSEVQPIKHAFEAGIKAQPGFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH56</accession>
    <name>B1KH56_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydantoinase/oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326697.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4112"/>
    <dbReference type="EnsemblBacteria" id="ACA88368">
        <property type="protein sequence ID" value="ACA88368"/>
        <property type="gene ID" value="Swoo_4112"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4112"/>
    <dbReference type="eggNOG" id="COG0145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007154_1_1_6"/>
    <dbReference type="OMA" id="GFPREAN"/>
    <dbReference type="OrthoDB" id="327092at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="2">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="209"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="538" mass="57819" checksum="006EFB7E43D49DD3" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH70</accession>
    <name>B1KH70_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326711.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4126"/>
    <dbReference type="EnsemblBacteria" id="ACA88382">
        <property type="protein sequence ID" value="ACA88382"/>
        <property type="gene ID" value="Swoo_4126"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4126"/>
    <dbReference type="eggNOG" id="ENOG50313M2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1165197_0_0_6"/>
    <dbReference type="OMA" id="QDYYFGL"/>
    <dbReference type="OrthoDB" id="53321at135622"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764471" evidence="1">
        <location>
            <begin position="20"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="25357" checksum="3C5FE5FAAF4FA3D7" modified="2008-04-29" version="1" precursor="true">MKYLWMACLCTAVAVPLEASELNLDFTNNKLELPDEVLATMRGKYTQSGQDYYFGLQMRTQYLTAQGVSRQVQMQVELSLLGDSPAVVVSIEEPVTVSDGSSVSLTSLGQQTGLQQKIQIAGDQNRALNDMDIGEGRLQALGGAQFDIGQTLISGDGHVVFSTQPGGLGYQVSLPGGSATQGVVINNGNGQLIQSINIGGAFHGVSNQAMIRYQGVDIASQHNQLMAQHINDLIVLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH80</accession>
    <name>B1KH80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1095</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323734.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1095"/>
    <dbReference type="EnsemblBacteria" id="ACA85388">
        <property type="protein sequence ID" value="ACA85388"/>
        <property type="gene ID" value="Swoo_1095"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1095"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_28_3_6"/>
    <dbReference type="OMA" id="TYEDRHT"/>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="218"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="432" mass="48360" checksum="8303F03A664CC37A" modified="2008-04-29" version="1">MRFESFSFAPEILRAISECGYQKMTPVQQQAIPAIRRGQDVLASAQTGTGKTAAFALPILQKMIDKPSETQRSNTRALILTPTRELASQIADNINDYSKHMQVSVLTIYGGVKLETQAQKIKRGVDIIVATPGRLLEHIQACNLNLSNVDFMVLDEADRMLDMGFVSDIQKVLQAVNKNSQKMLFSATFSSSVKKLANDFLDKPKLISVDKQNTTADTVSQVVYPVEQRRKRELVSELIGKKNWKQVLIFTATRDAADKLVKELNLDGIPSSVVHGEKAQGNRRRALREFKEGKVRVLVATEVAARGLDIQDLEYVVNYDLPFLAEDYVHRIGRTGRAGKSGVAISLVSREEERTLADIEKLIGKKLPRITIAGYEVGSRDLLIKHLQTRRSFAKKQNRQDNVSEQVIGERNMQGRRVKVKNSSNAKIKKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF7</accession>
    <name>B1KHF7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="4">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartate transcarbamylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1172</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323811.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1172"/>
    <dbReference type="EnsemblBacteria" id="ACA85465">
        <property type="protein sequence ID" value="ACA85465"/>
        <property type="gene ID" value="Swoo_1172"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1172"/>
    <dbReference type="eggNOG" id="COG0540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043846_1_2_6"/>
    <dbReference type="OMA" id="GDGPNEH"/>
    <dbReference type="OrthoDB" id="1844275at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="10">
        <location>
            <begin position="8"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="9">
        <location>
            <begin position="160"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="339" mass="37943" checksum="C9EF15E043352C61" modified="2008-04-29" version="1">MTQFQGSHILSVNQLDLDAVQQIFNVASRMTPYALRQKRTTVLDGAILGNLFFEPSTRTRISFGCAFNLLGGKVNETVGMASSSLSKGESLYDTARVLSSYSDVIAMRHPEAFSVKEFAQGSRVPVINGGDGSNEHPTQALLDLFTIQKELATQGQDISGMNIAMVGDLKFGRTVHSLSRLLCMYKDVTFTLVSPKELAMPDYVLNDIENAGHKITITDQLEGNLDQADILYLTRIQEERFPSQEEANKYRGKFRLNHTIYTKHCKSNTVIMHPLPRDSREQANELDNDLNSHPNLAIFRQADNGLLIRMALFALTLGVDTQLEKHECPVNWYSRKAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL6</accession>
    <name>B1KHL6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325241.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2624"/>
    <dbReference type="EnsemblBacteria" id="ACA86901">
        <property type="protein sequence ID" value="ACA86901"/>
        <property type="gene ID" value="Swoo_2624"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2624"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054568_0_0_6"/>
    <dbReference type="OMA" id="TAETRFP"/>
    <dbReference type="OrthoDB" id="848990at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="220"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="329" mass="36902" checksum="5DF4ECFA4343508F" modified="2008-04-29" version="1">MVSNRRKPGKIKQWFNQWLNSRLPAATKVTLAHRSVFILPSGFGLLWLTLVLLLFLFGTNYQNNLVIGLSLLLLSVFNTCIIYSYRNLAGMTISSTLSPQAYAGDTLVFPVRLYANQTQYEVLLNYPNNQIKVIKKVTNEASTSLIPFINERRGRVSPGRLKIESRYPLGLCKAWSHVDLDNEHIVYATPLEANEQLSHIDSEQDYVADNQGGHIPGVDEFKGLRQHIPGESLKQVAWKQLAQGRGMLTKEFQQPQGEPQWLSLTDFSPASLENRLSQLTHSVDRLSEKGQIFGLQLGERTIQPADGEAHRISCLQALALVPAQPETPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHM8</accession>
    <name>B1KHM8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sensor protein</fullName>
            <ecNumber evidence="14">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">Swoo_2636</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325253.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2636"/>
    <dbReference type="EnsemblBacteria" id="ACA86913">
        <property type="protein sequence ID" value="ACA86913"/>
        <property type="gene ID" value="Swoo_2636"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2636"/>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_10_6"/>
    <dbReference type="OMA" id="IKHSQGT"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029095">
        <property type="entry name" value="NarX-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042295">
        <property type="entry name" value="NarX-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016380">
        <property type="entry name" value="Sig_transdc_His_kin_NarX/NarQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13675">
        <property type="entry name" value="PilJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003167">
        <property type="entry name" value="STHK_NarX/NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 14 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12 14" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="18">
        <location>
            <begin position="189"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="17">
        <location>
            <begin position="393"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR003167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACA86913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="583" mass="65977" checksum="281FA2BC30812A5F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS9</accession>
    <name>B1KHS9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Porin Gram-negative type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4151</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326736.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4151"/>
    <dbReference type="EnsemblBacteria" id="ACA88407">
        <property type="protein sequence ID" value="ACA88407"/>
        <property type="gene ID" value="Swoo_4151"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4151"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038238_3_0_6"/>
    <dbReference type="OMA" id="VYGHYAM"/>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002299">
        <property type="entry name" value="Porin_Neis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00184">
        <property type="entry name" value="NEISSPPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764500" evidence="4">
        <location>
            <begin position="24"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="12"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="348" mass="37453" checksum="53FE16017146BEC3" modified="2008-04-29" version="1" precursor="true">MKKTLISASVASVLTLASFGALADGPNFYGRLDLSVTNSDKSSTLQSGTNGAEVGESGTYLENNFSHVGVKGSESLTSNIDVIYQMEFQVENTSGSGDVFKARNTFLGLKSTAGTVLVGRNDTVFKQAEGGVDIFGNTNADIDRLIGGQTRSSDGIWYYSPKIADLVTLNATYLMEDNQTDKAGNRIDENQYALSATIGDKKLKAQNYYVAAAYNTVGGIDAYRGVAQVKLGDFKIGGLFQNTESQTDSAQEGNSYFVNVAYNLNGVNLKAEYGKDEAGFGKYYKNITDVEGTDVNVQSITVGADYKVSKSTMVYGHYAMYEGDHKTAAGKVNLEDDNVFTVGVRYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV7</accession>
    <name>B1KHV7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsgA</name>
        <name evidence="7" type="ordered locus">Swoo_4179</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326764.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4179"/>
    <dbReference type="EnsemblBacteria" id="ACA88435">
        <property type="protein sequence ID" value="ACA88435"/>
        <property type="gene ID" value="Swoo_4179"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4179"/>
    <dbReference type="eggNOG" id="COG1162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033617_2_0_6"/>
    <dbReference type="OMA" id="CLVAAYD"/>
    <dbReference type="OrthoDB" id="908180at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="6">
        <location>
            <begin position="106"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="5">
        <location>
            <begin position="123"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="162"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="216"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="352" mass="39078" checksum="04EBACBB05FD432C" modified="2008-04-29" version="1">MSKKKPLSQGQRRRMRANQEKRLQRQDSGNNAPELQDSSLGPEQLGTVISRFGQHADIETESGQIVRCNMRRNIQSLVTGDKVIARLAQDIETGIAGVVEAVHPRHSSLSRPDLYDGIKIIAANIDQILIVSSVVPSFTTQIIDRYLVAAEDTGITPVIILNKIDLISDEERTSIEEALQRYRDIGYPVLKVSSKTGEGIDQIKALLNAKVSVFVGQSGVGKSSLINSMMPDAELLIGDVSENSGLGQHTTTTAKLLHFASGGDLIDSPGVREFALWHLPAERVGWCFIEFRDYLGTCKFRDCKHQNDPGCAITQAFNEGKITEDRYNNYHRIIASLDEQRHARHFRSDTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ6</accession>
    <name>B1KHZ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323820.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1181"/>
    <dbReference type="EnsemblBacteria" id="ACA85474">
        <property type="protein sequence ID" value="ACA85474"/>
        <property type="gene ID" value="Swoo_1181"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1181"/>
    <dbReference type="eggNOG" id="COG0347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082268_0_0_6"/>
    <dbReference type="OMA" id="YRGTEHV"/>
    <dbReference type="OrthoDB" id="2021322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="3">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12181" checksum="B1A406DC1D61AA33" modified="2008-04-29" version="1">MKLITAIIKPFKLDDVREALSSLGVQGLTVTEVKGFGRQKGHAELYRGAEYSVDFLPKIKLEIAISSGHEDEVIEAIINAANTGKIGDGKIFVSPLEQVVRIRTSEEGDEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI17</accession>
    <name>B1KI17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323841.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1202"/>
    <dbReference type="EnsemblBacteria" id="ACA85495">
        <property type="protein sequence ID" value="ACA85495"/>
        <property type="gene ID" value="Swoo_1202"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1202"/>
    <dbReference type="eggNOG" id="ENOG5032TUN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080432_0_0_6"/>
    <dbReference type="OMA" id="GLNTHSI"/>
    <dbReference type="OrthoDB" id="970661at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="34036" checksum="5F16C972EE3E1919" modified="2008-04-29" version="1" precursor="true">MSNYHRWVDRMQMIERKIRPSSVYLLFLVLVAFALGGLSMSLWFDNNQPKAQSNTDEIQKWTRELNAQAQVLASRNLELVLERETSDKMQQMFAEQHHKQRELERELNFYRSIMAPESSADGVTIEAIELTPSILPRQYRIQLILTQLQKRKQSLKGKSSIILVGQQAGKVVELDVAELLGDKKVFDFKFRYFQILEAEVTLPEGFELSRVKAKVSVPSSRWTKGSEAEVEYSAQQLLPQLATADKSADDADIKEALKNTLESKEPEEDNTPKPEGAIQTSAAAEALSASEKTDNGESVSE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI41</accession>
    <name>MUTH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA mismatch repair protein MutH</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Methyl-directed mismatch repair protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mutH</name>
        <name type="ordered locus">Swoo_1226</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MutH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323865.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI41"/>
    <dbReference type="SMR" id="B1KI41"/>
    <dbReference type="STRING" id="392500.Swoo_1226"/>
    <dbReference type="EnsemblBacteria" id="ACA85519">
        <property type="protein sequence ID" value="ACA85519"/>
        <property type="gene ID" value="Swoo_1226"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1226"/>
    <dbReference type="eggNOG" id="COG3066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086669_0_0_6"/>
    <dbReference type="OMA" id="EVMQLRP"/>
    <dbReference type="OrthoDB" id="1154974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006304">
        <property type="term" value="P:DNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00583">
        <property type="entry name" value="MutH_Sau3AI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00759">
        <property type="entry name" value="MutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004230">
        <property type="entry name" value="DNA_mismatch_repair_MutH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011337">
        <property type="entry name" value="DNA_rep_MutH/RE_typeII_Sau3AI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037057">
        <property type="entry name" value="DNA_rep_MutH/T2_RE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02976">
        <property type="entry name" value="MutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00927">
        <property type="entry name" value="MutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02248">
        <property type="entry name" value="mutH_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000133477" description="DNA mismatch repair protein MutH">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00759"/>
        </source>
    </evidence>
    <sequence length="231" mass="25638" checksum="162FB438FC5DC476" modified="2008-04-29" version="1">MTTPHSPKTIDELMSRANDMAGLTLGQLADSHGFITPANLKRDKGWVGQLIEHELGALAGSRPEPDFLHLGIELKTIPVDKNGKPIETTYVTVAPLIDIQGLTWETSVVCHKLQTVLWIPIQGDRDIPVSQRQIGSPILWRPNEEELALLKQDWEEIMEFIALGQVKQLTARHGEVLQLRPKGANSRSVTQSIGPNGSTQMTNPRGFYLKIPFTQSILSRAFGIYTQATSR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI69</accession>
    <name>RIMM_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rimM</name>
        <name type="ordered locus">Swoo_1255</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RimM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323893.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI69"/>
    <dbReference type="SMR" id="B1KI69"/>
    <dbReference type="STRING" id="392500.Swoo_1255"/>
    <dbReference type="EnsemblBacteria" id="ACA85547">
        <property type="protein sequence ID" value="ACA85547"/>
        <property type="gene ID" value="Swoo_1255"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1255"/>
    <dbReference type="eggNOG" id="COG0806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077636_1_0_6"/>
    <dbReference type="OMA" id="DEFYHAD"/>
    <dbReference type="OrthoDB" id="1497415at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="chain" id="PRO_1000089519" description="Ribosome maturation factor RimM">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="PRC barrel" evidence="1">
        <location>
            <begin position="96"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <sequence length="176" mass="20000" checksum="4A9B3603307BB1E5" modified="2008-04-29" version="1">MSSKQEPVVLGKIGSSHGIKGWLKITTYTESVEGIFDYSPWLIKEQGEWREVKVTQWRFQGKAVVASLEGVETRDQAQMLTNCEIAVSAEQMQELPEDEFYWRDLIGCEVTNTKGYNMGKVQEIVETGSNDVLLVKANAKDGFGKAERMIPFVTEQFVLEVNLTEKQILVDWDPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIN5</accession>
    <name>B1KIN5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M61 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326858.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4275"/>
    <dbReference type="EnsemblBacteria" id="ACA88531">
        <property type="protein sequence ID" value="ACA88531"/>
        <property type="gene ID" value="Swoo_4275"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4275"/>
    <dbReference type="eggNOG" id="COG3975">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078165_0_0_6"/>
    <dbReference type="OMA" id="WTLYHEL"/>
    <dbReference type="OrthoDB" id="679125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007963">
        <property type="entry name" value="Peptidase_M61_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05299">
        <property type="entry name" value="Peptidase_M61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767376" description="Peptidase_M61 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61" evidence="2">
        <location>
            <begin position="129"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="300" mass="34423" checksum="26AC8009B3229051" modified="2008-04-29" version="1" precursor="true">MKSLLSLTIAATLSWMTNLSSINSLQAAELTINYSGLSQEQIATVETWIHSGIGSVELTLSTIPQNTLTIEVMEKSGAREPVPWARVVRSRPIRVELHIDTNAKLDEFIQDWTLYHELSHLYLPLLNVNSFWLNEGFATYMQYLVMLRAQIITQTQYLARMENGLRRGKSTTLSHPGKLNEVAADMWRRGAFKRVYWSGAAYFAQIDQALIAQGSDLTQVIEQYSRCCLRKYSSGWQLVKQLDRISDSELFTSHYLQYSQRRDFPSISKQTLQQISLHYGTRTQLQALTKRPRHSESDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIS6</accession>
    <name>B1KIS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphoketolase</fullName>
            <ecNumber evidence="7">4.1.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1282</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XFP family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.9" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323920.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1282"/>
    <dbReference type="EnsemblBacteria" id="ACA85574">
        <property type="protein sequence ID" value="ACA85574"/>
        <property type="gene ID" value="Swoo_1282"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1282"/>
    <dbReference type="eggNOG" id="COG3957">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013954_2_0_6"/>
    <dbReference type="OMA" id="LSTMDHC"/>
    <dbReference type="OrthoDB" id="45239at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050193">
        <property type="term" value="F:phosphoketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018969">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PTHR31273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09363">
        <property type="entry name" value="XFP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="XFP_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="XFP_C" evidence="5">
        <location>
            <begin position="585"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="788" mass="89023" checksum="0E44DF02F69B15A5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV1</accession>
    <name>B1KIV1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SapC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323945.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1307"/>
    <dbReference type="EnsemblBacteria" id="ACA85599">
        <property type="protein sequence ID" value="ACA85599"/>
        <property type="gene ID" value="Swoo_1307"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1307"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074824_1_1_6"/>
    <dbReference type="OMA" id="DYPILFM"/>
    <dbReference type="OrthoDB" id="1512520at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010836">
        <property type="entry name" value="SapC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07277">
        <property type="entry name" value="SapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="26639" checksum="8FD1BA675398CD80" modified="2008-04-29" version="1">MTNISPLNSSKHLNTYIKESKDFSRFAAQSLIPIVVQEFAVLATEFPIVFVKNAESGQFTPIAMMGIKNNFNLYCQTKNWEASVTPIGFSKAPLSLMQTSKESDEVMVFIDEDSELVTSDEGNKLFDDSGEQTEYLKKRSNALLDLASFTQQTSAITQYFAELNLLAPKQLTVKLNSDSPEVNIDGVYIIDEQILNELNDEAFLTLKSKGLMPLIYAHLTSLHQIGRLITKQNQLDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ12</accession>
    <name>B1KJ12_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2756</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325368.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2756"/>
    <dbReference type="EnsemblBacteria" id="ACA87032">
        <property type="protein sequence ID" value="ACA87032"/>
        <property type="gene ID" value="Swoo_2756"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2756"/>
    <dbReference type="eggNOG" id="COG0633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_7_0_6"/>
    <dbReference type="OMA" id="YIELHIK"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="89"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="339" mass="38153" checksum="4C4C900D71ECD661" modified="2008-04-29" version="1">MTRFYFDEQSVESLEGETVLDALIRQGHSLNYSCRKGACKTCLVQHTGGDIPSGAQRGLTSELKSDAYICACQCKPTQDLKLKSILVQNLFITAHIHEKQYLSDSVVKILVEPSEEVSHSAGQYINLRRFDGLTRSYSITNDPDSKLIELHIRRKYNGQFSDWLFNHASVGESLLIQGPWGDCCYRSEYKNDTLILIGTGTGLGPVYGIIRDALSQGHKGEIYLYHGAKNEADLYHHSKLLKLMLEHRNMTYLACVEQMGSGKSSTRVQTGDPFEVAMSFHQFDSQTLSDSPQRVFLCGEPNFVNKGQELVFLNGTPLDRIHALSYEYKDLRKVPRDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ22</accession>
    <name>B1KJ22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ion transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_2766</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325378.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2766"/>
    <dbReference type="EnsemblBacteria" id="ACA87042">
        <property type="protein sequence ID" value="ACA87042"/>
        <property type="gene ID" value="Swoo_2766"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2766"/>
    <dbReference type="eggNOG" id="COG2126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011722_1_3_6"/>
    <dbReference type="OMA" id="KGIYWAI"/>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="12">
        <location>
            <begin position="30"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="31348" checksum="756E38266F8C711D" modified="2008-04-29" version="1">MEQDTQINQEDTIKLKLRRVIFGTDTRLGRYFDISLIICIILSVTLVFLDTVASINSQYGQLISVLEWFFTIVFTIEYLLRLYCSAQPVQYVRSFYGVVDLLSILPSYLALLFPGANFTLVIRILRLFRIFRVLKLLRYLSEGNVLLRAMLQSGRKVFIFFFSVSLIVMVLSAIMYVVEGPGNGFTSIPKSIYWTIVTITTVGYGDITPGTNLGQAIAAFTMLLGYSIIAIPTGILTAEISQEMGKSKDLRRCSNCLKTGHESDACYCDHCGSELEAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ32</accession>
    <name>B1KJ32_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325388.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2776"/>
    <dbReference type="EnsemblBacteria" id="ACA87052">
        <property type="protein sequence ID" value="ACA87052"/>
        <property type="gene ID" value="Swoo_2776"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2776"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122429_0_0_6"/>
    <dbReference type="OMA" id="DLGAMLY"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="16657" checksum="98AE25CAA2D44D50" modified="2008-04-29" version="1" precursor="true">MVHALWLQNFISVYSELGVNNLTSLHQIYHREIEFSDPLHRVDGIDELMSYFDSLYTNIDECTFHIDTVFSCENQAAIYWTMTFCHSKLNSGEKIVVEGHSHLVERDNKVVMHRDYLDVGSMLYEHIPLLGKAVKAIKRRAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJB4</accession>
    <name>B1KJB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326912.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4333"/>
    <dbReference type="EnsemblBacteria" id="ACA88586">
        <property type="protein sequence ID" value="ACA88586"/>
        <property type="gene ID" value="Swoo_4333"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4333"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016838_1_2_6"/>
    <dbReference type="OMA" id="GNPHLHF"/>
    <dbReference type="OrthoDB" id="1703187at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766704" evidence="1">
        <location>
            <begin position="26"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="33080" checksum="9CFD8DA08BAF9791" modified="2008-04-29" version="1" precursor="true">MRINSNLAKVAALALTLGYTSLASAELNIFACEPEYAALAKELAPDAKIYSATTAMQDPHQVQARPSLIAKMRQADLAICAGADLEVGWLPMLQMKSSNAKVRSTDQGLFFAADHIDALDKLASVDRSMGDVHAQGNPHLHFSPLRVLKVAEALSQKLISLDPDSKAQYQSALREFSAKWNQAIPQWEAKAARLKGKKVIAYHSNFRYLFNWIGIEQVGDLEPKPGLPPSSSHLASLLKRTEVGDVMAIIVASYQSERGAEWLGERANLPVVVLPMSVGGNSQSQDLFSLYDSVIDLLLNLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJE1</accession>
    <name>B1KJE1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326939.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4360"/>
    <dbReference type="EnsemblBacteria" id="ACA88613">
        <property type="protein sequence ID" value="ACA88613"/>
        <property type="gene ID" value="Swoo_4360"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4360"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047522_1_0_6"/>
    <dbReference type="OMA" id="SFHRSFK"/>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="247"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="345" mass="38903" checksum="CC7C58BC972A992F" modified="2008-04-29" version="1">MPVIKAPSSPSLGTTSMPPVQQFLQAARHCKVDISAALALVGIDKATLYDADARIDGEQFQRLLHHLIEHSEHPLFGLYSARFIQPDRFTILGQIGLNSDNFAQALKQAMPLEKLVGDMGSTELREHPQGLKMVWHCQYSHPLVIPHLIDNVLASWVNFARFLMEDNRATAVEVKLQRSQPSLQEVKDYQTLFACPVLFEQSENAILIDKAMLTRPLPSGDNRRLPQLMANAQQRLKHMGSDDQLQLATARVIRQLLPQGTISRDLVANQLHLTGRTLQRKLLKQGVSYQTLVDNIRHEMADYWLACSELSASEIAVELGFSDVRVFFRAYKNWSGHSPGVKRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJN9</accession>
    <name>B1KJN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PfaD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324058.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1420"/>
    <dbReference type="EnsemblBacteria" id="ACA85712">
        <property type="protein sequence ID" value="ACA85712"/>
        <property type="gene ID" value="Swoo_1420"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1420"/>
    <dbReference type="eggNOG" id="COG2070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040029_0_0_6"/>
    <dbReference type="OMA" id="KRGTMFP"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04742">
        <property type="entry name" value="NPD_FabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014179">
        <property type="entry name" value="PfaD_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040981">
        <property type="entry name" value="PfaD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18328">
        <property type="entry name" value="PfaD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02814">
        <property type="entry name" value="pfaD_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfaD_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="94"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="545" mass="59520" checksum="0E4EA53913D9025F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR7</accession>
    <name>B1KJR7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3291 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1450"/>
    <dbReference type="EnsemblBacteria" id="ACA85740">
        <property type="protein sequence ID" value="ACA85740"/>
        <property type="gene ID" value="Swoo_1450"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1450"/>
    <dbReference type="eggNOG" id="COG2329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119287_0_0_6"/>
    <dbReference type="OMA" id="VNMSVWQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021708">
        <property type="entry name" value="DUF3291"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11695">
        <property type="entry name" value="DUF3291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3291" evidence="1">
        <location>
            <begin position="10"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="18562" checksum="E7E7289CA1D3B175" modified="2008-04-29" version="1">MSKHDVEMELAQLNIAKARGEMDEPLMKEFVDNLESVNAMAESSEGFIWRLKDESGDATAIQAFDDPLLLVNMSVWQSPDALKGFMYMTHHISFMKRKKEWFEKLTQANYVLWWVPKGHIPDVEEGKLRLEHLREHGESPYAFSFKSRFEPSDLVITKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK62</accession>
    <name>B1KK62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4441</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327019.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4441"/>
    <dbReference type="EnsemblBacteria" id="ACA88693">
        <property type="protein sequence ID" value="ACA88693"/>
        <property type="gene ID" value="Swoo_4441"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4441"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="MFSINQL"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032255">
        <property type="entry name" value="HBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01358">
        <property type="entry name" value="HBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51753">
        <property type="entry name" value="HBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="HBM" evidence="8">
        <location>
            <begin position="48"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="322"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="381"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="654" mass="70168" checksum="EC79AB9AAEE1C021" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK77</accession>
    <name>B1KK77_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dissimilatory sulfite reductase</fullName>
            <ecNumber evidence="1">1.8.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide = [protein]-dithiol + 2 AH2 + H(+) + sulfite</text>
            <dbReference type="Rhea" id="RHEA:51676"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </cofactor>
        <text evidence="1">Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="1">Binds 8 heme c groups covalently per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; sulfite reduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the multiheme cytochrome c family.</text>
    </comment>
    <dbReference type="EC" id="1.8.99.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327034.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4456"/>
    <dbReference type="EnsemblBacteria" id="ACA88708">
        <property type="protein sequence ID" value="ACA88708"/>
        <property type="gene ID" value="Swoo_4456"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4456"/>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_406457_0_0_6"/>
    <dbReference type="OMA" id="CHPAQYE"/>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="UniPathway" id="UPA00370"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016002">
        <property type="term" value="F:sulfite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009061">
        <property type="term" value="P:anaerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02023">
        <property type="entry name" value="Sulfite_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023155">
        <property type="entry name" value="Cyt_c-552/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032897">
        <property type="entry name" value="Sulfite_reductase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13435">
        <property type="entry name" value="Cytochrome_C554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0763">Sulfate respiration</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009007468" description="Dissimilatory sulfite reductase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_C554" evidence="3">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>6</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>6</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>6</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>6</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>8</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>7</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>7</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>7</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>8</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>8</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="561"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>8</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="645"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>7</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="676" mass="76047" checksum="03116C757E457F54" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKB2</accession>
    <name>B1KKB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324098.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1464"/>
    <dbReference type="EnsemblBacteria" id="ACA85752">
        <property type="protein sequence ID" value="ACA85752"/>
        <property type="gene ID" value="Swoo_1464"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1464"/>
    <dbReference type="eggNOG" id="ENOG50300P6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171115_0_0_6"/>
    <dbReference type="OMA" id="TCELAYV"/>
    <dbReference type="OrthoDB" id="2047841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767146" evidence="1">
        <location>
            <begin position="23"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12354" checksum="D850FC5AC1A95D19" modified="2008-04-29" version="1" precursor="true">MDTLKKLFVSLVFLFVSSSVSAVCFERGCSNVYVEKLYVNASGVVYVGTSGDERLMTCDAVSDVYSTFRSTDAGGDMIFSTLLAAQLSNKKVFVRTVESSNECKIAYVTLDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKK4</accession>
    <name>B1KKK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325557.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2948"/>
    <dbReference type="EnsemblBacteria" id="ACA87221">
        <property type="protein sequence ID" value="ACA87221"/>
        <property type="gene ID" value="Swoo_2948"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2948"/>
    <dbReference type="eggNOG" id="ENOG502ZBVY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104628_0_0_6"/>
    <dbReference type="OMA" id="WGWVAIS"/>
    <dbReference type="OrthoDB" id="1929580at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009476">
        <property type="entry name" value="DUF1097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06496">
        <property type="entry name" value="DUF1097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="18168" checksum="38627E09827C6836" modified="2008-04-29" version="1" precursor="true">MEHRWQVAISAGLLAAVWAGVADIFHLITWIGFLSCSTYFALGKLNFQGVIISWATNLSGVFWAWLVISGSSYFETPMVGYLLTGVVTAAMCLQASYSKLAFIPGAFIGCCITFAMGGEIGKILPALIIGSLLGYSMSELTSVLVALKLKWHKRLQGNGAAISSPNHTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN9</accession>
    <name>B1KKN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325592.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2985"/>
    <dbReference type="EnsemblBacteria" id="ACA87256">
        <property type="protein sequence ID" value="ACA87256"/>
        <property type="gene ID" value="Swoo_2985"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2985"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_310985_0_0_6"/>
    <dbReference type="OMA" id="NTSTMND"/>
    <dbReference type="OrthoDB" id="224536at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038440">
        <property type="entry name" value="FimV_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020011">
        <property type="entry name" value="Motility_prot_FimV_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020012">
        <property type="entry name" value="Motility_prot_FimV_N"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03505">
        <property type="entry name" value="FimV_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03504">
        <property type="entry name" value="FimV_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="415"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="750"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="499"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="572"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="629"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="683"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="788"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="812"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="884"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="914"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1135" mass="123012" checksum="F54F81FF7218E4B4" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR7</accession>
    <name>B1KKR7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3013</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325620.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3013"/>
    <dbReference type="EnsemblBacteria" id="ACA87284">
        <property type="protein sequence ID" value="ACA87284"/>
        <property type="gene ID" value="Swoo_3013"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3013"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095692_0_0_6"/>
    <dbReference type="OMA" id="PRRCVYL"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="4">
        <location>
            <begin position="11"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="177" mass="19025" checksum="3C89ED08EAEB5007" modified="2008-04-29" version="1">MSADSKYLAQIGLVNPKSPTNVGGIMRAAGCYQADAVLYTGKRYELAARNGNAQYNTDTKRAGQHIPLQAVESLLAAKVDDVKLVCVDLVVGAISLPEFVHPDKALYVFGPEDGTIGQEIIDKADAVVYVPTVGCMNLAASVNVLLYDRLAKLGCLDANDELIKRSRDTNNRVKVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKT0</accession>
    <name>B1KKT0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_3026</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325633.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3026"/>
    <dbReference type="EnsemblBacteria" id="ACA87297">
        <property type="protein sequence ID" value="ACA87297"/>
        <property type="gene ID" value="Swoo_3026"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3026"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_16_1_6"/>
    <dbReference type="OMA" id="PFRYMDT"/>
    <dbReference type="OrthoDB" id="977512at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008692">
        <property type="term" value="F:3-hydroxybutyryl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012802">
        <property type="entry name" value="FadJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02440">
        <property type="entry name" value="FadJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="13">
        <location>
            <begin position="312"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="12">
        <location>
            <begin position="494"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="12">
        <location>
            <begin position="626"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="713" mass="76626" checksum="5AF9FF63B56E4CA2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY1</accession>
    <name>B1KKY1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ordered locus">Swoo_4537</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327113.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4537"/>
    <dbReference type="EnsemblBacteria" id="ACA88787">
        <property type="protein sequence ID" value="ACA88787"/>
        <property type="gene ID" value="Swoo_4537"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4537"/>
    <dbReference type="eggNOG" id="COG0770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031507_4_0_6"/>
    <dbReference type="OMA" id="VEMGANH"/>
    <dbReference type="OrthoDB" id="1861122at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="106"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="313"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="107"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="48690" checksum="80229624BC15A83F" modified="2008-04-29" version="1">MIRLTLSLLSQRLNGRLIGSDTEILNVCSDSRSIPEKTLFVALKGEKFDGHDFAHLALENGASALLVSRELALDIPQLLVSDTQKAMGEIGAYLKELVQPKSVALTGSNGKTSVKEMVASILSQHHKVLYTAGNFNNEIGVPLTLLRLEGDEEYGVFELGANHLGEIDYTSSLVKPDVAMVNNVASAHLEGFGSLEGVAKAKSEIFNHLSADGIAVINLDDPFADVMRGAASQFTQLTFAIESQADVKASELVSDSLGRYRFTLNYLNSCESITLPLSGRHQVSNALAATAICLSLGLSLEEVLSGLKLVEPVKGRMLPHELGRVRIIDDSYNANPASVGAAIDWLQEIDGFRCLVLGDLGELGDNASLLHSELGEYAKKQGIDALFTLGELSENTAAAFGGQHQQELAPLVLCLINTINQLQGDVTVLVKGSRSAGMERVVEALKIAHGQGEFV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL07</accession>
    <name>DUT_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="1">dUTPase</shortName>
            <ecNumber evidence="1">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dut</name>
        <name type="ordered locus">Swoo_4563</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dUTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327138.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL07"/>
    <dbReference type="SMR" id="B1KL07"/>
    <dbReference type="STRING" id="392500.Swoo_4563"/>
    <dbReference type="EnsemblBacteria" id="ACA88813">
        <property type="protein sequence ID" value="ACA88813"/>
        <property type="gene ID" value="Swoo_4563"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4563"/>
    <dbReference type="eggNOG" id="COG0756">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068508_1_1_6"/>
    <dbReference type="OMA" id="YAAFVHP"/>
    <dbReference type="OrthoDB" id="1669228at2"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0546">Nucleotide metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000094994" description="Deoxyuridine 5'-triphosphate nucleotidohydrolase">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="71"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <sequence length="152" mass="16156" checksum="B863D5E14D50FE50" modified="2008-04-29" version="1">MKTPIEVKILDSRIGSEYPLPAYATPGSAGMDLRAMIETSLSVAPGETRLIPTGISIHVADPSLAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVSCWNRGDKPYTIEIGDRLAQLVFVPVVQAEFKLVDEFDNSLRGEGGFGHSGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL73</accession>
    <name>B1KL73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322763.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0113"/>
    <dbReference type="EnsemblBacteria" id="ACA84414">
        <property type="protein sequence ID" value="ACA84414"/>
        <property type="gene ID" value="Swoo_0113"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0113"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_2_3_6"/>
    <dbReference type="OMA" id="EKPNAGM"/>
    <dbReference type="OrthoDB" id="1033671at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="4"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="364" mass="40701" checksum="6F10A9663B800D43" modified="2008-04-29" version="1">MSTLFSPGRIGNMTLKNRFVRSATWENMATETGHMTDKLYSVYEELAQGEVGLIVTGYANIVAEEKPNAGMMGMYDDSFIVEYQKLTELVHGYDSKIVMQLAYGGTKTTFNVGERVIFAPSAIAERGTQTLGKAMTKEEIDYIVKAFAQASLRAQKSGFDGVEIHAAHTYLINQFLSPYYNQRQDEYGGSLENRMRFLLEIYAEIRKLVGEDYPVLVKLTASEFFEGGLTFDETRTICKKLESIGVDAIIISGNIHGNANTVVGESFDGYTIQNEGYFREFGAVVSEEVNLPIITVGGLADICAIEELAETTNIQFFALSRPLLAEPQLIKRWLAGSKVEVDCERCSKCRTKRGNFCVVYRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL87</accession>
    <name>B1KL87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322777.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0127"/>
    <dbReference type="EnsemblBacteria" id="ACA84428">
        <property type="protein sequence ID" value="ACA84428"/>
        <property type="gene ID" value="Swoo_0127"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0127"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_5_3_6"/>
    <dbReference type="OMA" id="VVRYWQQ"/>
    <dbReference type="OrthoDB" id="1819702at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="90"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="217" mass="25354" checksum="B75E575C259FA50F" modified="2008-04-29" version="1">MELFYHPLSRYSQKVLLALYEKQANFYPRVVELSDPLSRQDFCQFYPPGKVPLLKSKKGVLLPESSIIIEYIDNEFSKKGTRLLPISPSLALDTRLQDRLIDLELSNVLFEYEQQKLNPEDTNHIKLKQLEKSIKRFLQYLDDILETSHWVCGDSLTLADCALIPCLLYAKDHFQIFKYDNLSRYWAQAQLRGAYLQVKEEIELAETEVLIGRRPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD3</accession>
    <name>B1KLD3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6268 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324204.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1572"/>
    <dbReference type="EnsemblBacteria" id="ACA85858">
        <property type="protein sequence ID" value="ACA85858"/>
        <property type="gene ID" value="Swoo_1572"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1572"/>
    <dbReference type="eggNOG" id="ENOG502ZT65">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076884_0_0_6"/>
    <dbReference type="OMA" id="YYFNGEL"/>
    <dbReference type="OrthoDB" id="1738720at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046235">
        <property type="entry name" value="DUF6268"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19783">
        <property type="entry name" value="DUF6268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6268" evidence="1">
        <location>
            <begin position="77"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="33666" checksum="DF5012016A281D4D" modified="2008-04-29" version="1" precursor="true">MINGSINICLKRAIVVSLLSSVVYLPSVSASGKPSFSPFSVSVSRIDTAEADIGEGQNTLQRSSWLFDANAKLPLNKQWSLGFNLGYGDLNYDWKQDGSSILNRQLQGWQQVHRYSAGVSLSYRLNKHWMFMVAPKLQYAYADTAKSSNASSYGVVASGMYRFGNGNLLGLGVAYLNDISEVRTVPFLAVNWQINDSWRLGNPFAAGFTGPAGLELSYQLSPSVDFGFGASKRTQRFLLEDDDTTVEVDEWVSFLRAGWRVSESVTLTGYAGYYFNGELELNKPQVEVETIDSQGALAIAAEYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS0</accession>
    <name>B1KLS0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3096</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0283 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325703.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3096"/>
    <dbReference type="EnsemblBacteria" id="ACA87367">
        <property type="protein sequence ID" value="ACA87367"/>
        <property type="gene ID" value="Swoo_3096"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3096"/>
    <dbReference type="eggNOG" id="COG3768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057693_0_0_6"/>
    <dbReference type="OMA" id="MFFIAWR"/>
    <dbReference type="OrthoDB" id="1529001at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021147">
        <property type="entry name" value="DUF697"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006507">
        <property type="entry name" value="UPF0283"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39342">
        <property type="entry name" value="PTHR39342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05128">
        <property type="entry name" value="DUF697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01620">
        <property type="entry name" value="hyp_HI0043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="365" mass="40794" checksum="C062439CF689AA71" modified="2008-04-29" version="1">MKDETSLKKSQRFDAHAQEAEPQLRGAQHFDEKELQFIPEVITEPANSDDDIGAVVDDKLGKTHDKVKRRKPWSLLAKLSCIGVGLLIVTETLLGLKAAWVESPWLFGLYFSVISVVVLWAGNIALSEWRKLVRLKSVEESQQVGDRLSQSLQSGEADKFINRLIDKLPSEVSLEPYLASVRDEHNDAEKLILFDDLVLSDRDLKAKKLVRRFAQESALLLAASPLAVLDMAIILWRNQRMIYKIAECYGIELGYWSRIKLIRGVIVNIIYAGASEVATDLGTQLLSVEMTGKLSARLAQGLGGGLLTARLGYQAMALCRPISFKEGARPKLSGIHKELLLELKEFSSGIMTKEPIRNKDFTKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLU3</accession>
    <name>B1KLU3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">tRNA--hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325726.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3119"/>
    <dbReference type="EnsemblBacteria" id="ACA87390">
        <property type="protein sequence ID" value="ACA87390"/>
        <property type="gene ID" value="Swoo_3119"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3119"/>
    <dbReference type="eggNOG" id="COG4445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056571_0_0_6"/>
    <dbReference type="OMA" id="CEFKAAS"/>
    <dbReference type="OrthoDB" id="1900811at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045301">
        <property type="term" value="F:tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07910">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010386">
        <property type="entry name" value="tRNA-Hydrxlase_MiaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42637">
        <property type="entry name" value="PTHR42637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06175">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020736">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="29126" checksum="DF7906DC234E364B" modified="2008-04-29" version="1">MQQLLAPIHAFLKCETPDSWIQAAIKPENLPTLLIDHCNCELKAAQTAMFLVRKYAVEQQSGKQLLEWAKPYEEFVYRKDRDIAVFLARSSKKNDVSIELTAKAGFEQGDALISKMVRLIKEEFHHFEQVLEIMLERGIPYENRRAGRYAKGMMKMVRTHEPAAMIDKLIIGAFIEARSCERFAKLAPYLDEVLNKFYVSLLRSEARHYQDYLLLAEDIAGGDISERVAIIAEREAELISSIDPEFNFHSGAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV0</accession>
    <name>B1KLV0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327155.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4580"/>
    <dbReference type="EnsemblBacteria" id="ACA88830">
        <property type="protein sequence ID" value="ACA88830"/>
        <property type="gene ID" value="Swoo_4580"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4580"/>
    <dbReference type="eggNOG" id="COG3152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036810_0_0_6"/>
    <dbReference type="OMA" id="LCGYEFS"/>
    <dbReference type="OrthoDB" id="1587411at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="346" mass="37986" checksum="4C3E24903EE9C361" modified="2008-04-29" version="1">MQYKSLFCIKGRDNWQRFSAISGSLYLTLLLGFVLIGGGGALIFLALLLAPLLGLSALRRVRDIERPSWLAALTLLPFMFFSLSLAYSGSAMASLTCGVIAGLMTVFLSAQKSKVGGGLYQQGYSGPLVVPRRERSRSRVEPTLGGGAYEEEQEQVSYQETEYASPQKSRATFELWLTWAKQNQKLLTAVLGGALFLMVLSSLWSIWGGSDEESVEPEQVEMPAQNPVERDEVTLPDGFSLVLEDKLLIMRWLGEADNPGVIWSLATAKGDRSCANLVFNNGSEYRPMIVEMMADTSIEARFTPLDTGKIITDIALRGEVKLCGYEFSLKGSQSALSKSDAFIPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM19</accession>
    <name>B1KM19_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327223.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4649"/>
    <dbReference type="EnsemblBacteria" id="ACA88899">
        <property type="protein sequence ID" value="ACA88899"/>
        <property type="gene ID" value="Swoo_4649"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4649"/>
    <dbReference type="eggNOG" id="ENOG5032YZ5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110739_1_1_6"/>
    <dbReference type="OMA" id="AQIYKYT"/>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767480" description="DUF4124 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="2">
        <location>
            <begin position="8"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20399" checksum="74FE5C6FB167741E" modified="2008-04-29" version="1" precursor="true">MRLLLTFFLLAFTFASSAAVYKWVDKDGKTHFSDKPIENSEEVEFKSNTQNQITPSPIQAISRNADNNEELAPSTQYSVRIQSPKEEETIRENSGDVTVMARISPDLKPDHLLVILMDDKVMGSAQTTPIFSLKNIPRGEHTFVIKAVAQNGKQLASSPPRKIYLHRAIVNNSKKPTPFGKGS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM36</accession>
    <name>RS4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsD</name>
        <name type="ordered locus">Swoo_4666</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327240.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KM36"/>
    <dbReference type="SMR" id="B1KM36"/>
    <dbReference type="STRING" id="392500.Swoo_4666"/>
    <dbReference type="EnsemblBacteria" id="ACA88916">
        <property type="protein sequence ID" value="ACA88916"/>
        <property type="gene ID" value="Swoo_4666"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4666"/>
    <dbReference type="eggNOG" id="COG0522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092403_0_2_6"/>
    <dbReference type="OMA" id="NVVFRMG"/>
    <dbReference type="OrthoDB" id="1211060at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000140793" description="30S ribosomal protein S4">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="S4 RNA-binding" evidence="1">
        <location>
            <begin position="96"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <sequence length="206" mass="23391" checksum="2C0A2FE92C76B67E" modified="2008-04-29" version="1">MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKLETAPGQHGARKTRLSEYGVQLREKQKVRRTYGVLEKQFRNYYKDAARTKGNTGENLLTLLETRLDNVVYRMGFGATRAEARQLVSHKSIMVNGSVVNIPSFKVSANDVISIREKSKKQARIIAALEVSSQREKPTWVEVDNTKMEGAFKRLPERSDLSAEINEQLIVELYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM38</accession>
    <name>B1KM38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322800.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0150"/>
    <dbReference type="EnsemblBacteria" id="ACA84451">
        <property type="protein sequence ID" value="ACA84451"/>
        <property type="gene ID" value="Swoo_0150"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0150"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="NIHGEGF"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="136"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="136"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="241" mass="27428" checksum="15BBCC43D025E747" modified="2008-04-29" version="1">MGQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQNGSPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTPDVPGAPTQQEEEITFGEFALNLATREMYHGEEAISLTSGEFAVLKVLVSHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIERDPANPRYIQTVWGLGYVFVPDGAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM57</accession>
    <name>B1KM57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transport protein SCO1/SenC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322819.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0169"/>
    <dbReference type="EnsemblBacteria" id="ACA84470">
        <property type="protein sequence ID" value="ACA84470"/>
        <property type="gene ID" value="Swoo_0169"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0169"/>
    <dbReference type="eggNOG" id="COG1999">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050131_3_2_6"/>
    <dbReference type="OMA" id="GELKGHW"/>
    <dbReference type="OrthoDB" id="1994201at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="43"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="23473" checksum="9C85EB4618EA89CB" modified="2008-04-29" version="1" precursor="true">MSKRLTVVISTIFGLALLGLGVAAAIQFKSHRAEPELATSFIFPTAKKLAPFSLKDQHGNLFSNSQLADKWSLFFIGYTSCPDVCPTTMGKLSAAYPELLKDIDLQIIFLSVDPQRDTQEKLLAYMDFFNPEFTAITGEHAQLFPLTRDLGFVYAMVGEGENYQVDHSASMALISPEGRKVAIIKPKSSTPGTLPQILTKNLISDIGKIVSTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM85</accession>
    <name>B1KM85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0197"/>
    <dbReference type="EnsemblBacteria" id="ACA84498">
        <property type="protein sequence ID" value="ACA84498"/>
        <property type="gene ID" value="Swoo_0197"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0197"/>
    <dbReference type="HOGENOM" id="CLU_1481048_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="182" mass="21189" checksum="640371E06F824E24" modified="2008-04-29" version="1">MVVFLLLVISFNVYTEEIEGIPNFNRIRVISECNESQPFGIKLSLVNSGEFDYFFPKVALPQNGAMLKSNFNIALYDQLDDYPLNFSEEKINFKTDEADQLNEFSDLVIKKGEEYRERVNILKYYDLDPARKYLVSLESFFETYNEKTYRSYGITSSILVFEGGLCRNITNEELNVMLRGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMK0</accession>
    <name>B1KMK0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1713</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324344.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1713"/>
    <dbReference type="EnsemblBacteria" id="ACA85998">
        <property type="protein sequence ID" value="ACA85998"/>
        <property type="gene ID" value="Swoo_1713"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1713"/>
    <dbReference type="eggNOG" id="COG1087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_6"/>
    <dbReference type="OMA" id="KVMTGQY"/>
    <dbReference type="OrthoDB" id="1597849at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="4"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="338" mass="36644" checksum="2E0688F8311C8CE5" modified="2008-04-29" version="1">MTILVTGGAGYIGSHTVVELLNTDQEVVIIDNLVNSSIEALHRVESITGKSVTFYQGDVLNKAFLQKVFTDHKIQAVIHFAGLKAVGESVAQPLRYYETNVSGTLVLCEVMAENDVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVENILEDLYQSDPSWNIARLRYFNPVGAHASGSIGEDPNDIPNNLMPFIAQVAVGKRDKLSVFGDDYNTHDGTGVRDYIHVVDLAIGHLKALEKLNTQSGLVTYNLGTGVGYSVIDMVNAFEKACGKSISYQIVARRPGDIAACYADPLKAKTELGWQATHSLEDMANSSWKWQSSNPNGYASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ9</accession>
    <name>B1KMQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3166</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325773.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3166"/>
    <dbReference type="EnsemblBacteria" id="ACA87437">
        <property type="protein sequence ID" value="ACA87437"/>
        <property type="gene ID" value="Swoo_3166"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3166"/>
    <dbReference type="eggNOG" id="COG1117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="AFMYMGD"/>
    <dbReference type="OrthoDB" id="1416748at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="26"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="272" mass="30446" checksum="E44CA5D2523FD5AB" modified="2008-04-29" version="1">MISIDKSAMSTNEIDLNNLSQEETALEIRNLDLKYGDKQALFDVSMKIPEKQVTAFIGPSGCGKSTLLRCINRMNDLVDNCHIGGEILLNGQNIYDKKVDVAALRRNVGMVFQRPNPFPKSIYENVVYGLRLQGVNNRRALDEAAERSLRGAAIWDEVKDRLHDNAFGLSGGQQQRLVIARAIAIEPEVLLLDEPTSALDPISTLTIEELITELKSKYTVVIVTHNMQQAARVSDQTAFMYMGELVEYADTNTIFTTPKTRKTEDYITGRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMT3</accession>
    <name>B1KMT3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325797.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3190"/>
    <dbReference type="EnsemblBacteria" id="ACA87461">
        <property type="protein sequence ID" value="ACA87461"/>
        <property type="gene ID" value="Swoo_3190"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3190"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_6"/>
    <dbReference type="OMA" id="DWMGQWT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="320"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="352"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="531" mass="59644" checksum="78C8E3BB83CCBDEA" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMW4</accession>
    <name>RL15_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplO</name>
        <name type="ordered locus">Swoo_4671</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327244.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMW4"/>
    <dbReference type="SMR" id="B1KMW4"/>
    <dbReference type="STRING" id="392500.Swoo_4671"/>
    <dbReference type="EnsemblBacteria" id="ACA88921">
        <property type="protein sequence ID" value="ACA88921"/>
        <property type="gene ID" value="Swoo_4671"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4671"/>
    <dbReference type="eggNOG" id="COG0200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055188_4_2_6"/>
    <dbReference type="OMA" id="FKNINRV"/>
    <dbReference type="OrthoDB" id="1874945at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142881" description="50S ribosomal protein L15">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="144" mass="14973" checksum="B5226FD96499CA0C" modified="2008-04-29" version="1">MRLNTLSPAAGSKSAAKRVGRGIGSGTGKTCGRGHKGQKSRSGGGVRIGFEGGQMPLKIRLPKFGFTSRKAMVSAEVRISELAKVNGDVVDLSTLKDANLVTRNIQFAKIVLSGTIERPVTVKGLKVTKGARAAIEAAGGKIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX7</accession>
    <name>B1KMX7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="12" type="ordered locus">Swoo_4684</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327256.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4684"/>
    <dbReference type="EnsemblBacteria" id="ACA88934">
        <property type="protein sequence ID" value="ACA88934"/>
        <property type="gene ID" value="Swoo_4684"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4684"/>
    <dbReference type="eggNOG" id="COG0092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058591_0_2_6"/>
    <dbReference type="OMA" id="KTNPIGN"/>
    <dbReference type="OrthoDB" id="1132353at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="25630" checksum="A0580FAA38818F21" modified="2008-04-29" version="1">MGQKVHPNGIRLGITKPWISTWYADKSDYANNLTSDWEVRKFLEKNLKQASVSKIVIERPAKSVRVTIHTARPGVVIGKKGEDVEKLRNAVAKLTGIPAQINIAEIRKPELDAKLVAEGIASQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARSEWYREGRVPLHTLRADIDYSTAESHTQYGVIGVKVWVFKGEVLDGVLPAHEEPKQQPKRKPRGK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX9</accession>
    <name>RS19_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsS</name>
        <name type="ordered locus">Swoo_4686</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006083596.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMX9"/>
    <dbReference type="SMR" id="B1KMX9"/>
    <dbReference type="STRING" id="392500.Swoo_4686"/>
    <dbReference type="EnsemblBacteria" id="ACA88936">
        <property type="protein sequence ID" value="ACA88936"/>
        <property type="gene ID" value="Swoo_4686"/>
    </dbReference>
    <dbReference type="GeneID" id="58510898"/>
    <dbReference type="GeneID" id="67441764"/>
    <dbReference type="KEGG" id="swd:Swoo_4686"/>
    <dbReference type="eggNOG" id="COG0185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144911_0_1_6"/>
    <dbReference type="OMA" id="FPEMVGH"/>
    <dbReference type="OrthoDB" id="1893906at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000128037" description="30S ribosomal protein S19">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <sequence length="92" mass="10472" checksum="BA5BA2044F49FEEF" modified="2008-04-29" version="1">MPRSLKKGPFIDLHLLKKVEKAMEAGDKKPIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTDEMIGHKLGEFSPTRTYRGHAADKKAKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN89</accession>
    <name>B1KN89_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Aconitate hydratase B</fullName>
            <ecNumber evidence="5 16">4.2.1.3</ecNumber>
            <ecNumber evidence="6 16">4.2.1.99</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">2-methylisocitrate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ordered locus">Swoo_0285</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="5 16"/>
    <dbReference type="EC" id="4.2.1.99" evidence="6 16"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322935.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0285"/>
    <dbReference type="EnsemblBacteria" id="ACA84586">
        <property type="protein sequence ID" value="ACA84586"/>
        <property type="gene ID" value="Swoo_0285"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0285"/>
    <dbReference type="eggNOG" id="COG1049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016536_0_0_6"/>
    <dbReference type="OMA" id="QDTTGAM"/>
    <dbReference type="OrthoDB" id="32104at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01576">
        <property type="entry name" value="AcnB_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004406">
        <property type="entry name" value="Aconitase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015933">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036288">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015929">
        <property type="entry name" value="Aconitase_B_swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06434">
        <property type="entry name" value="Aconitase_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11791">
        <property type="entry name" value="Aconitase_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036687">
        <property type="entry name" value="AcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74778">
        <property type="entry name" value="SSF74778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00117">
        <property type="entry name" value="acnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12 17" id="KW-0408">Iron</keyword>
    <keyword evidence="13 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9 16" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase_B_N" evidence="21">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_2_N" evidence="20">
        <location>
            <begin position="168"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase" evidence="19">
        <location>
            <begin position="471"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="18">
        <location>
            <begin position="244"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="18">
        <location>
            <begin position="414"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="710"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="769"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="772"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="791"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="796"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR036687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR036687-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR036687-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF06434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF11791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ACA84586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="865" mass="94004" checksum="F946149EA4411EF9" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN91</accession>
    <name>DCUP_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="1">UPD</shortName>
            <shortName evidence="1">URO-D</shortName>
            <ecNumber evidence="1">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hemE</name>
        <name type="ordered locus">Swoo_0287</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322937.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KN91"/>
    <dbReference type="SMR" id="B1KN91"/>
    <dbReference type="STRING" id="392500.Swoo_0287"/>
    <dbReference type="EnsemblBacteria" id="ACA84588">
        <property type="protein sequence ID" value="ACA84588"/>
        <property type="gene ID" value="Swoo_0287"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0287"/>
    <dbReference type="eggNOG" id="COG0407">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040933_0_0_6"/>
    <dbReference type="OMA" id="LWLMRQA"/>
    <dbReference type="OrthoDB" id="1104410at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0210">Decarboxylase</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000100019" description="Uroporphyrinogen decarboxylase">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="27"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <sequence length="354" mass="39512" checksum="E06CE464BB0B1694" modified="2008-04-29" version="1">MAELKNDRYLRALLKQPVDRTPVWMMRQAGRYLPEYKATRAEAGDFMSLCKNQDLACEVTLQPLRRYDLDAAILFSDILTIPDAMGLGLYFETGEGPRFQRPTDTIDAIKKLSIPDPEDELGYVMRAVSTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKTFEKIKKMAYEEPATLHMLLDKLADSVILYLNAQVANGAQSLMIFDSWGGALSHHAYREFSLRYMQKIVDGLTRHADGRQVPVTLFTKGGGLWLESMAETGCDALGLDWTVDIGDARRRVGHKVALQGNMDPSVLYASPERIHQEVDQILSSYGEGTGHVFNLGHGIHQHVDPEHAGAFINSVHELSAKYHK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI3</accession>
    <name>ISCS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cysteine desulfurase IscS</fullName>
            <ecNumber evidence="1">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">iscS</name>
        <name type="ordered locus">Swoo_1776</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324406.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNI3"/>
    <dbReference type="SMR" id="B1KNI3"/>
    <dbReference type="STRING" id="392500.Swoo_1776"/>
    <dbReference type="EnsemblBacteria" id="ACA86060">
        <property type="protein sequence ID" value="ACA86060"/>
        <property type="gene ID" value="Swoo_1776"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1776"/>
    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_2_6"/>
    <dbReference type="OMA" id="KGLYWAR"/>
    <dbReference type="OrthoDB" id="839689at2"/>
    <dbReference type="UniPathway" id="UPA00266"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0001">2Fe-2S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000119649" description="Cysteine desulfurase IscS">
        <location>
            <begin position="1"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="1">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="203"/>
            <end position="205"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via persulfide group" evidence="1">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared with IscU</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00331"/>
        </source>
    </evidence>
    <sequence length="404" mass="44526" checksum="F7E06A640EA5528E" modified="2008-04-29" version="1">MKLPIYLDYAATTPVDPRVAEKMMQCMTMDGIFGNPASRSHRYGWQAEEAVDIARNQVADLINADPREIVFTSGATESDNLAIKGVAHFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPEANGLIPLATIESAMREDTVLVSIMHVNNEIGVIHDINAIGELCRSKKIIFHVDAAQSAGKLPLDVQETKVDLLSISAHKMYGPKGIGALYVRRKPRIRLEAAMHGGGHERGMRSGTLATHQIVGMGEAAAIAKADMEADNARIAGLRDRLWNGVKGIEETYINGDVEQRYCGSLNVSFNFVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTEEEIDHAIETINKSIDSLRDMSPLWEMFKDGVDLEQVQWAHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNV3</accession>
    <name>B1KNV3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325897.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3291"/>
    <dbReference type="EnsemblBacteria" id="ACA87561">
        <property type="protein sequence ID" value="ACA87561"/>
        <property type="gene ID" value="Swoo_3291"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3291"/>
    <dbReference type="eggNOG" id="ENOG502Z9WC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069808_0_0_6"/>
    <dbReference type="OMA" id="PWIWFLK"/>
    <dbReference type="OrthoDB" id="632187at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021936">
        <property type="entry name" value="DUF3549"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12069">
        <property type="entry name" value="DUF3549"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="38166" checksum="C2AE49112AAAA6F3" modified="2008-04-29" version="1">MTEITTLTQFLTTANTQFQVYDMGRRVQHIDMLAFQQIENLASSYPSPIQGHAQFAIVFWDASQQHYIWFLKLPLDERGLLSPAPRTQFIRMIIEALGRDPSQALSKEQQQKLANHPFSFKPTSEKLALFNALVKKQLGQVASPQYEFAYQYLSKQLKAEHWQEVGLQGLADICVRANELDHLNVLIDSFDFAATEVQVAVCQCLEHLEIDEQLADTVLEKLKLADNELKPYYLRALASDEQSSIDGIAHLAELNLLDANVLITIAARNWLALKETQTRKIFLEALAKQEQHFFNQIFADIVAIPALRTQLLSELRNPDRSEVLSAAIGGLFKVTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNW0</accession>
    <name>B1KNW0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325904.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3298"/>
    <dbReference type="EnsemblBacteria" id="ACA87568">
        <property type="protein sequence ID" value="ACA87568"/>
        <property type="gene ID" value="Swoo_3298"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3298"/>
    <dbReference type="eggNOG" id="COG5595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1064102_0_0_6"/>
    <dbReference type="OMA" id="ELQFECF"/>
    <dbReference type="OrthoDB" id="1598701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016908">
        <property type="entry name" value="UCP029037"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10071">
        <property type="entry name" value="DUF2310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029037">
        <property type="entry name" value="UCP029037_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="257" mass="29541" checksum="B9C04A17BB5AC734" modified="2008-04-29" version="1">MHVVELRFECFDNTTITAAEKAINGLLEAYRANGQVLGREFAVAFNEGDFKVRLLMPEKSSLAKRYNSPWVNAALAELTTAKLLAPREKYIGQDINSEVSSSDKPSWQLLYTSYVHMCSPIRNGDTLQPIPLYQLPATFNGDHKRVIRWQTEWQACDELQMAAATKAEFAALEELTSTKSDLFRRGWDIRGRVEFQTKIPTYYYLYRVGGDSLAAEKERPCPRCGNQEWLLDEPLLDMFHFRCDECRIVSNISWDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP41</accession>
    <name>B1KP41_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327389.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4823"/>
    <dbReference type="EnsemblBacteria" id="ACA89072">
        <property type="protein sequence ID" value="ACA89072"/>
        <property type="gene ID" value="Swoo_4823"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4823"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_2_1_6"/>
    <dbReference type="OMA" id="MMAAIME"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="16189" checksum="654445CA4936A409" modified="2008-04-29" version="1">MQRYRISTELSEMDIDVIHGFVSESYWAKGIPKSVLKKALMNSLCFGVFTDDNAQIGFGRLITDRATYAYLADVFILDEYRGLGLSKALMTNIVSHPDLQGLRRMVLATRDAHGLYAKFGFETVPNPETLMQVWQPEVYSVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP70</accession>
    <name>B1KP70_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Type IV pilus secretin PilQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0339</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial secretin family. PilQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322989.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0339"/>
    <dbReference type="EnsemblBacteria" id="ACA84640">
        <property type="protein sequence ID" value="ACA84640"/>
        <property type="gene ID" value="Swoo_0339"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0339"/>
    <dbReference type="eggNOG" id="COG4796">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006756_0_1_6"/>
    <dbReference type="OMA" id="QNVPWDQ"/>
    <dbReference type="OrthoDB" id="870677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021731">
        <property type="entry name" value="AMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013355">
        <property type="entry name" value="Pilus_4_PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11741">
        <property type="entry name" value="AMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02515">
        <property type="entry name" value="IV_pilus_PilQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="STN" evidence="9">
        <location>
            <begin position="295"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="682" mass="75131" checksum="A0B9CC03DC423AF3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP83</accession>
    <name>B1KP83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LppC family lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0352</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323002.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0352"/>
    <dbReference type="EnsemblBacteria" id="ACA84653">
        <property type="protein sequence ID" value="ACA84653"/>
        <property type="gene ID" value="Swoo_0352"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0352"/>
    <dbReference type="eggNOG" id="COG3107">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026091_1_0_6"/>
    <dbReference type="OMA" id="MRLYAMG"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007443">
        <property type="entry name" value="LpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38038">
        <property type="entry name" value="PTHR38038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04348">
        <property type="entry name" value="LppC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="634" mass="70805" checksum="731CE71A79918031" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP85</accession>
    <name>B1KP85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323004.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84655">
        <property type="protein sequence ID" value="ACA84655"/>
        <property type="gene ID" value="Swoo_0354"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0354"/>
    <dbReference type="HOGENOM" id="CLU_1049292_0_0_6"/>
    <dbReference type="OrthoDB" id="2224265at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="265" mass="31563" checksum="24045ECBB9E74725" modified="2008-04-29" version="1">MSDWKCEDKEWMKQRKKEWPQYRFNISDALVEVTDLVKDEMEDLKNYFLIGDKSALKTIYKIRSGLLLELWLHPSEDIEVLKQVFNRHREEKTHYCETPAYRVNERNKFYSLAKHRHKVPFKGASRLNGREWVIDQVFMPQTLEEFIAIEGEEQRDFIIGKFCIGPCYEWGDFLTRTERFDTDICVNKIDIWKSAVKLSFEQYKDEKGIVWLIEDLDTFLASNDEKHPKQIKLAQDIIDAINDPEMPQALRDRVAEIRASKYATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD8</accession>
    <name>B1KPD8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323057.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0409"/>
    <dbReference type="EnsemblBacteria" id="ACA84708">
        <property type="protein sequence ID" value="ACA84708"/>
        <property type="gene ID" value="Swoo_0409"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0409"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054727_0_0_6"/>
    <dbReference type="OMA" id="HHSWADI"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="87"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="34920" checksum="4F9AACA3D6617FDC" modified="2008-04-29" version="1">MGGILSLIRGSLAFVCWVVNTLFWVLPIVLLSPIKLIPIPALRTAISSLLDNCATAWISINGVIERIFHPVKIDLHSNAELTPKEWYMVIANHQSWVDILILQRVLNRKIPFLKFFLKKELIFVPFLGLAWWALDFPFMRRYSTAQLRRNPKLKGKDIEITRRACAKFKSKPVSVMNFVEGTRFKAEKHQQQNSQFKHLLKPKAGGLAFALSAMGEHINKLVNVSIYYPEKVPSYWEYISGQVKEVRVHITVTEIPDEMRGDYMKDRDFKIAFQEQLNLIWQEKDQMLDLLAQDNQVKQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM9</accession>
    <name>B1KPM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324528.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1898"/>
    <dbReference type="EnsemblBacteria" id="ACA86182">
        <property type="protein sequence ID" value="ACA86182"/>
        <property type="gene ID" value="Swoo_1898"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1898"/>
    <dbReference type="eggNOG" id="ENOG5033A7C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1958078_0_0_6"/>
    <dbReference type="OrthoDB" id="1923951at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14584" checksum="7BCE62980C068BE5" modified="2008-04-29" version="1">MNYYYLVAALLALSTLIIHIHHGRKHYLFPMLSSELDPVVKAVFHCVFHFVSLFILLSTIILAACGFDLISMMQGYGLVLFIALNFGIFAIWQLFLAFDSEIPSPFRRLFQWMPFAGIAILSLVGSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ18</accession>
    <name>B1KQ18_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327448.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4882"/>
    <dbReference type="EnsemblBacteria" id="ACA89131">
        <property type="protein sequence ID" value="ACA89131"/>
        <property type="gene ID" value="Swoo_4882"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4882"/>
    <dbReference type="eggNOG" id="ENOG5032S46">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148512_0_1_6"/>
    <dbReference type="OMA" id="SAEMCGD"/>
    <dbReference type="OrthoDB" id="1677662at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="8721" checksum="186084C9CE092367" modified="2008-04-29" version="1">MNCRLGCGACCIAPSITSPIPGMPNGKLAGERCVQLSDDNLCKIFGMDERPEVCSSFSAALDVCGKTNAEALYLISTLECQTS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ88</accession>
    <name>ILVD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="1">DAD</shortName>
            <ecNumber evidence="1">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ilvD</name>
        <name type="ordered locus">Swoo_0445</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27695"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="1">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323092.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ88"/>
    <dbReference type="SMR" id="B1KQ88"/>
    <dbReference type="STRING" id="392500.Swoo_0445"/>
    <dbReference type="PRIDE" id="B1KQ88"/>
    <dbReference type="EnsemblBacteria" id="ACA84743">
        <property type="protein sequence ID" value="ACA84743"/>
        <property type="gene ID" value="Swoo_0445"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0445"/>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014271_4_2_6"/>
    <dbReference type="OMA" id="TQGRNMA"/>
    <dbReference type="OrthoDB" id="193579at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0001">2Fe-2S</keyword>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000089414" description="Dihydroxy-acid dehydratase">
        <location>
            <begin position="1"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="1">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <sequence length="616" mass="65461" checksum="9220C7B0E0C736DD" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH5</accession>
    <name>B1KQH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324560.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1930"/>
    <dbReference type="EnsemblBacteria" id="ACA86214">
        <property type="protein sequence ID" value="ACA86214"/>
        <property type="gene ID" value="Swoo_1930"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1930"/>
    <dbReference type="eggNOG" id="COG3146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036032_1_0_6"/>
    <dbReference type="OMA" id="HFEVCYY"/>
    <dbReference type="OrthoDB" id="891566at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007434">
        <property type="entry name" value="FemAB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04339">
        <property type="entry name" value="FemAB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="405" mass="46419" checksum="650C91EE86446CA1" modified="2008-04-29" version="1">MSEIQIEFIPAISLISAQEWNQLMVTSSDEGASVNPFVRHEYLAALESSGCVCAKTGWTPMHLTVLQGEKRLAVMPLYEKTHSYGEYVFDWAWAEAYERNSIDYYPKLLCAIPFTPVTGPRVGMAKSLTQSEAALVWSKITEHFSEMLQKSGYSSWHALFLTKPECDMFSKQNALSRVGTQFHWMNKGYQSFEDYLAAMNSRKRKDIRKERYRVAQHGLTMRFVDGGEVTDEQWLAFTHCYQMTYAKRSGHYGYLNLSFFKSLAQNMPQQIKLLLVETNEGDSGADYEDKQGQRIIASALYFCSDTHLYGRYWGALETIEGLHFEVCYYQGIEYCIAQGLQTFDAGAQGEHKVPRGFEPVAIYSNHDIAHPAFRDAIEHFTHQERTQISCYMKEMSQSLPFKSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQL0</accession>
    <name>B1KQL0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324595.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1965"/>
    <dbReference type="EnsemblBacteria" id="ACA86249">
        <property type="protein sequence ID" value="ACA86249"/>
        <property type="gene ID" value="Swoo_1965"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1965"/>
    <dbReference type="eggNOG" id="ENOG503273Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153126_1_0_6"/>
    <dbReference type="OMA" id="AYIPMAW"/>
    <dbReference type="OrthoDB" id="1754298at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="14345" checksum="DBEBC9B523B09CDD" modified="2008-04-29" version="1" precursor="true">MKTILAVLVGIFLGSLVNMGIVTLGGELVHPPKGVDVTDMESLASSMHLFEPRHYLFPFLAHALGTLVGAFVAGKIAATGLYRPSLFIGGFFLLGGIASSVILPAPAWFITLDLVLAYIPMSWLGFWLSNKLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM9</accession>
    <name>B1KQM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly PilZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324614.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1984"/>
    <dbReference type="EnsemblBacteria" id="ACA86268">
        <property type="protein sequence ID" value="ACA86268"/>
        <property type="gene ID" value="Swoo_1984"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1984"/>
    <dbReference type="eggNOG" id="COG3215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147899_0_0_6"/>
    <dbReference type="OMA" id="CNKIETY"/>
    <dbReference type="OrthoDB" id="1538398at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="13"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="108" mass="11911" checksum="823990FDC633180A" modified="2008-04-29" version="1">MTDLVVNFDTLHHLYRAYMPFIQPVGLFVSTSESHYLGQELTIAYQLPGSTTKLEFKGSVVWINPLGASGGRPAGIGVKIITEPETHKHHIENLLSRELASGDQTCTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQN3</accession>
    <name>B1KQN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1988"/>
    <dbReference type="EnsemblBacteria" id="ACA86272">
        <property type="protein sequence ID" value="ACA86272"/>
        <property type="gene ID" value="Swoo_1988"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1988"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072800_0_0_6"/>
    <dbReference type="OMA" id="WHMTAAF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767566" evidence="1">
        <location>
            <begin position="21"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="33447" checksum="B3B90126D31DEFB9" modified="2008-04-29" version="1" precursor="true">MLGKIGISVLGLLIASPCWAQEPMSSLPEDDSKSVIRIGGFYSNSNSSMDVTNPILGNDFEIDFEQDLKLEESQFLPFFEVFYHFNDKHSLYIDWKQLHRNADVQQITTPFQVNLDDQIYDIQLGAKIKTTLNIDIARIGYGYNFLQGNNYNLGLSLGLHAMFIETGFEGNIGACIDGGSLDTCGATPTNQMVEESVTAPLPDIGVYGDYEFMPGFRFTAHAQYFYIKLDDLKGNLVDIRAGVEAEITENWHMTAAFNYYEVDVDYVHKATQSDLHVANYNLHYSFIGPMLSVSYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR86</accession>
    <name>B1KR86_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CbiA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323251.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0607"/>
    <dbReference type="EnsemblBacteria" id="ACA84903">
        <property type="protein sequence ID" value="ACA84903"/>
        <property type="gene ID" value="Swoo_0607"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0607"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_672572_0_0_6"/>
    <dbReference type="OMA" id="MSEITPN"/>
    <dbReference type="OrthoDB" id="1046589at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="154"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="411" mass="46275" checksum="718AC143AD865C59" modified="2008-04-29" version="1">MFDLAKVITKNSEQTREQAGPASCSFYYQSSECLELIEQVFRFEGWNVPDCIKSSTPGELQLDALKDIVILELNNSKNVVKDAREFAAKLPNQKGVIVIGKEDTITTLRELKEMGIYYLFWPLNQEELSEFLRHVHNNLQHLSGVNKNRKAKRVAVVGTKGGIGNTMITCELAATLAYQGVDTIQVDHQYFNSNTDILLGLKKFERQDTDNLSLQLRDMDEVSASNYLSKVDEHWRLLAFGGSQSAEALYSDSQNIADLLSRQANFIIEDFSSSNDFVMDPALLSDRVDLFVIVLDATVSSVRNASQIIEKIELHNLSGTADIRILTFLNIHRPEGGFPLKKDEVERYLARPVDVQLDYAANFSALMLSGKRLHRLEKRSGAFNKLAQLIQGKQPELASSPLNRFKALVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRC1</accession>
    <name>B1KRC1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2044</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324674.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2044"/>
    <dbReference type="EnsemblBacteria" id="ACA86328">
        <property type="protein sequence ID" value="ACA86328"/>
        <property type="gene ID" value="Swoo_2044"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2044"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_6"/>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="6"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="412" mass="43030" checksum="AAC2BB2744DF01B2" modified="2008-04-29" version="1">MSKRRVVVTGLGLVTPVGNTVDSSWEALLAGQSGIAPITKFDASEFTTRFSGSVKDFDVEQYMSKKDARKMDLFIQYGMAAGIQAMTDSGLDMAKLDPSRVGTAVGAGMGGMPLIEQGHSALLKGGPRKISPFFVPSTIINMISGHLSIKYGMTGPNFAVTTACTTGVHNIGFAARTIAYGDADVMIAGGAEDVTCPLAVGGFGSAKALSTRNDEPQAASRPWDKDRDGFVIGDGAGVMVMEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPADGAGAAAAMVNAIKDAKLEKEQVGYINAHGTSTPAGDKAEVAAVKSVFGDHAYKLLVSSTKSMTGHLLGAAGSVEAIITLLALRDQVIPPTLNLDNPDEGCDLDFVPHTARQHEFEYALCNSFGFGGTNGSLLFKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD5</accession>
    <name>B1KRD5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Adenosylmethionine decarboxylase</fullName>
            <ecNumber evidence="1">4.1.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.50" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324687.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2058"/>
    <dbReference type="EnsemblBacteria" id="ACA86342">
        <property type="protein sequence ID" value="ACA86342"/>
        <property type="gene ID" value="Swoo_2058"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2058"/>
    <dbReference type="eggNOG" id="ENOG502Z9Q6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023050_1_0_6"/>
    <dbReference type="OMA" id="CYQRKNE"/>
    <dbReference type="OrthoDB" id="1542140at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001985">
        <property type="entry name" value="S-AdoMet_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570">
        <property type="entry name" value="PTHR11570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01536">
        <property type="entry name" value="SAM_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="309" mass="35328" checksum="BB5E8A799D709BBD" modified="2008-04-29" version="1">MFFEGSEKRVEVLVSPTTRSLRLLDEQFWSDVVACADAEVLSKMGNECCDAYLLSESCLFVWDDKFLMLTCGTTTLVDAVIFFVDKLGESAIASVSYQRKSEYLSHLQTSSFEEDLSRLRTKLSGSAYRVGHLDTHHHYIFTSDPQTQPLKVKSNSELLMYHIKGEVADYLRSDAQSCEGIRELLALEHLFPDFCFDDHLFTPFGYSINGLWEDKYMTIHITPQEQSSYVSIETNLHFELYPFNIFSALLNKLNPQSWDVIGFNRQVITDGFPPFVSVASCALPINNNETVQFNQYQQLNSELLQPELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRJ6</accession>
    <name>B1KRJ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326094.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87761">
        <property type="protein sequence ID" value="ACA87761"/>
        <property type="gene ID" value="Swoo_3497"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3497"/>
    <dbReference type="eggNOG" id="ENOG5033MD0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2304106_0_0_6"/>
    <dbReference type="OrthoDB" id="2198800at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11440" checksum="D0CFBF28551A6EB2" modified="2008-04-29" version="1">MNSQPWVKIYDDEAWDDSIVGNREGLLALKQAIDDALENECVEVADRFKSDFGVVAFTDQDWEQTEPTEVKGIWGVVIPFILFLWAVVLPLFAIYKLAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD76</accession>
    <name>B1KD76_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3649</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3649"/>
    <dbReference type="EnsemblBacteria" id="ACA87911">
        <property type="protein sequence ID" value="ACA87911"/>
        <property type="gene ID" value="Swoo_3649"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3649"/>
    <dbReference type="eggNOG" id="COG0733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006855_3_3_6"/>
    <dbReference type="OMA" id="NLWGFAY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="PTHR11616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00610">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="498" mass="54874" checksum="09D2CA35322AC641" modified="2008-04-29" version="1">MVEFMKREQWNSRIGFILAAVGSAIGLGNIWRFPYMAYENGGGAFFIPYLFAMLSAGIPFMIMEFSLGHKLRGASPKIFSKLGENYGLRLEWLGWFQVFIAAIIAIYYVAVIGWAISFFSFSFDQSWGGDTNAFFFGEYLKIGDHSPTSLGGFQLHIAIPMAIAWSITFMAIFTGVKGGIERASKIMMPLLFFMVLILIGRIVFLPGALEGLNYLFQPDFSKIMDAKVWSAAYGQIFFTLSVGFAIMLAYSSYLPEKSDINNNAFMTVLINCGFSILAGVLIFAILGYMAQEQAKPLTEVVSSGVGLAFVTIPAAINLLPAPYIFGPLFFFALVVAGLSSHISIIEAVTSALIDKLCMPRKKAAIIVCGSGFIISMAFATNGGLLLLDLVDYFINNVALLFSCFAELIILAWLFKIADVREYANRISDFTIGSWMDLCLRFISPAMLAIILVKNLINTVNNGYGDYPITDQLILGWGLIAFMLFVSLIINLASNKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDB4</accession>
    <name>B1KDB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative plasmid transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323263.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0619"/>
    <dbReference type="EnsemblBacteria" id="ACA84915">
        <property type="protein sequence ID" value="ACA84915"/>
        <property type="gene ID" value="Swoo_0619"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0619"/>
    <dbReference type="eggNOG" id="ENOG502Z8UB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037007_1_0_6"/>
    <dbReference type="OMA" id="AWHNDLV"/>
    <dbReference type="OrthoDB" id="1178526at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032811">
        <property type="entry name" value="Put_conjugal_transfer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13729">
        <property type="entry name" value="TraF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764706" evidence="1">
        <location>
            <begin position="21"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="397" mass="43351" checksum="77DEDC404C7F772C" modified="2008-04-29" version="1" precursor="true">MKKLKYAVYFALLLPFTTMAGQQYYEARSDAMGGTGVASSNREGAAFINPALLALQTPQFNDFSLLLPVLGADGADKDQMIDKFDALEESYDGLEAAINASNAAAIDRFRTDLINDLESLKDNTAYVSAGVGFSLVIPNDKMPMAVFYKSYIDAIGVTAIEQSDIDALTVIDPNNPPEVSDLDSQGAVVAGAVSDLGVAISFPLSIVNMPISVGVSPKFQRIDTYNYVVSANNFESSDFNDSKYRNDESTFNLDIGVAMQPIEGLVVGLSGRNLISQDVDTVEAQGRKFTYQVEPLFTAGIAYDWESLTLTSDIDLNTHKRFDEIEGTQYWRLGGEVRALDWLALRMGYRHDMKDNTSNIYSLGTGFSIGQTFYLDFTGMMGSDDAIGGVLQTSYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG9</accession>
    <name>B1KDG9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323317.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0674"/>
    <dbReference type="EnsemblBacteria" id="ACA84970">
        <property type="protein sequence ID" value="ACA84970"/>
        <property type="gene ID" value="Swoo_0674"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0674"/>
    <dbReference type="HOGENOM" id="CLU_2131834_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12663" checksum="D42DFF7A8E592C29" modified="2008-04-29" version="1">MKIKTKVRLISALMGFALTLGFLIFQLLEFDFGLEPDRISYGQSYLLKPISVYGGSSYKAAKAQSVGRFKLPSNTVIHSKIYAPPNKGYYCVSEVLVNGKVSHYLSIQYDRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDH7</accession>
    <name>B1KDH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323325.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84978">
        <property type="protein sequence ID" value="ACA84978"/>
        <property type="gene ID" value="Swoo_0682"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0682"/>
    <dbReference type="HOGENOM" id="CLU_1863807_0_0_6"/>
    <dbReference type="OrthoDB" id="1992363at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15642" checksum="1AE4A477374D0423" modified="2008-04-29" version="1" precursor="true">MKHRAFIVSALLLSGCTSTSNIDPLLVSKLSGVWDEINSEMCSSNYHTVEFDSSTLILKYVDKGYISENDGRNILKYRILSQSPDSIRVVLDDETRLDNDNKPVVWHLKSLNNDQYCWGRDDWPEGSCTPSRHRCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM7</accession>
    <name>B1KDM7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate dehydrogenase</fullName>
            <ecNumber evidence="2">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324769.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2140"/>
    <dbReference type="EnsemblBacteria" id="ACA86424">
        <property type="protein sequence ID" value="ACA86424"/>
        <property type="gene ID" value="Swoo_2140"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2140"/>
    <dbReference type="eggNOG" id="COG2902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003404_1_1_6"/>
    <dbReference type="OMA" id="RATRWFL"/>
    <dbReference type="OrthoDB" id="79339at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019551">
        <property type="term" value="P:glutamate catabolic process to 2-oxoglutarate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028971">
        <property type="entry name" value="NAD-GDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007780">
        <property type="entry name" value="NAD_Glu_DH_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43403">
        <property type="entry name" value="PTHR43403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05088">
        <property type="entry name" value="Bac_GDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036761">
        <property type="entry name" value="GDH_Mll4104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1614" mass="182363" checksum="3387FC74D1D77D64" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM8</accession>
    <name>PYRD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydroorotate dehydrogenase (quinone)</fullName>
            <ecNumber evidence="1">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">DHOdehase</fullName>
            <shortName evidence="1">DHOD</shortName>
            <shortName evidence="1">DHODase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrD</name>
        <name type="ordered locus">Swoo_2141</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-dihydroorotate + a quinone = a quinol + orotate</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="1">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324770.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDM8"/>
    <dbReference type="SMR" id="B1KDM8"/>
    <dbReference type="STRING" id="392500.Swoo_2141"/>
    <dbReference type="EnsemblBacteria" id="ACA86425">
        <property type="protein sequence ID" value="ACA86425"/>
        <property type="gene ID" value="Swoo_2141"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2141"/>
    <dbReference type="eggNOG" id="COG0167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013640_2_0_6"/>
    <dbReference type="OMA" id="ERIKMGA"/>
    <dbReference type="OrthoDB" id="1109542at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00225">
        <property type="entry name" value="DHO_dh_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0288">FMN</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000100289" description="Dihydroorotate dehydrogenase (quinone)">
        <location>
            <begin position="1"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="62"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="111"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="246"/>
            <end position="247"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="318"/>
            <end position="319"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00225"/>
        </source>
    </evidence>
    <sequence length="340" mass="36486" checksum="D748B6901B6C6687" modified="2008-04-29" version="1">MFYKLAQKVMFQMDPEKAHHFALNSLMATANTPLDCFYAQKIAPSPVEFMGVTFPNPVGLAAGMDKDGECIDGFHAMGFGHIEVGTVTPRPQPGNDLPRLFRLKPAKGIINRMGFNNKGVDNLIANLKAAKSGALIGVNIGKNKDTPVEQGKDDYLICMDKVYEYAAYIAVNISSPNTPGLRSLQYGDLLDDLLGSLKAKQKDLAQKHGKYVPIALKIAPDLSDEEIQKIADSLIKNQFDGAIATNTTLSRDGVSGLMNANETGGLSGKPLNLLSTSVIKKLSSCLNGQIPIIGVGGINSAADAIDKLDAGASMVQIYSGFIYQGPKLIKDIIEACRVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDP4</accession>
    <name>B1KDP4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0229 protein Swoo_2157</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0229 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2157"/>
    <dbReference type="EnsemblBacteria" id="ACA86441">
        <property type="protein sequence ID" value="ACA86441"/>
        <property type="gene ID" value="Swoo_2157"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2157"/>
    <dbReference type="eggNOG" id="COG2718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049702_0_0_6"/>
    <dbReference type="OMA" id="QYFAYIE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01232">
        <property type="entry name" value="UPF0229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006698">
        <property type="entry name" value="UPF0229"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30510">
        <property type="entry name" value="PTHR30510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04285">
        <property type="entry name" value="DUF444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="428" mass="49293" checksum="9B7682DB127C5712" modified="2008-04-29" version="1">MTWEVRMANFIDRRLNAKGKSTVNRQRFINRYKQQIKKSVSDAVTRRSVTDVDKGEKIGIPTKDISEPSFHQGQGGVRERVHPGNDQFTRGDKIERPPSGGGQGAGQGEASDSGEGQDDFVFQISKDEYLELLFEDLELPNLQNNRLNKLVEYQTYRAGFTNDGVPANINIVRSLRSSLARRIAMSSSKKKALKELINELEELENTPGAEAERILFLKQEIEELKQKIAKVPFIDTFDLRYNNFAKKEIPSSQAVMFCIMDVSGSMDQATKDMAKRFYILLYLFLTRTYKNLDVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMHQIQKERYPESEWNIYAAQASDGDNWADDSPGCKTLLEKKLLPVVRYFSYIEITNRAHQTLWREYESLQKSFDNIAVQHIKQAEDIYPVFRELFKKQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ1</accession>
    <name>B1KDQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaA regulatory inactivator Hda</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324792.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2164"/>
    <dbReference type="EnsemblBacteria" id="ACA86448">
        <property type="protein sequence ID" value="ACA86448"/>
        <property type="gene ID" value="Swoo_2164"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2164"/>
    <dbReference type="eggNOG" id="COG0593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072265_1_1_6"/>
    <dbReference type="OMA" id="DWGQIYR"/>
    <dbReference type="OrthoDB" id="1110566at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032297">
        <property type="term" value="P:negative regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017788">
        <property type="entry name" value="Hda"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03420">
        <property type="entry name" value="DnaA_homol_Hda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_DnaA" evidence="2">
        <location>
            <begin position="93"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="26396" checksum="5171C965ACDCA86F" modified="2008-04-29" version="1">MKSNSPIQLSLPVHLPDDETFNSYYPAAGNDELIQSLQACAEGSSERSVYLWGPVKSGRTHLMHAACAHANDLQRSSFYLPLGIHASISTALLEGLESLDLICIDDVDAIAGHPLWEEAIFDLYNRVSEHKNCSLIVSASVSPNDSGFTLPDLISRMQWGLNYQLQPMADEEKLAALQRRAAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASLVHQRKLTIPFVKEMLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDS6</accession>
    <name>B1KDS6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Swoo_2191</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324817.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2191"/>
    <dbReference type="EnsemblBacteria" id="ACA86473">
        <property type="protein sequence ID" value="ACA86473"/>
        <property type="gene ID" value="Swoo_2191"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2191"/>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_7_0_6"/>
    <dbReference type="OMA" id="CNAEWAL"/>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="20" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="151"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="249"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="451"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="499"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACA86473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="566" mass="62354" checksum="7E531B7044C4666F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET5</accession>
    <name>B1KET5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326430.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88100">
        <property type="protein sequence ID" value="ACA88100"/>
        <property type="gene ID" value="Swoo_3841"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3841"/>
    <dbReference type="HOGENOM" id="CLU_1926148_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14839" checksum="A77097F634474FA2" modified="2008-04-29" version="1">MKYFFFLFLIVAFDVLAISDYCKAISNSYCNVSLVAMVSSPDDYNERKIIVSGTFKQNGDKYYLFIDSEKAKNNLFVDSIRIDISEGLAGEILKSSAEVNFVTFKGTFYTNNFDGSFGTLKNVVMWFDGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV1</accession>
    <name>B1KEV1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323449.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0807"/>
    <dbReference type="EnsemblBacteria" id="ACA85102">
        <property type="protein sequence ID" value="ACA85102"/>
        <property type="gene ID" value="Swoo_0807"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0807"/>
    <dbReference type="eggNOG" id="COG3036">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170842_1_2_6"/>
    <dbReference type="OMA" id="GSYNRKQ"/>
    <dbReference type="OrthoDB" id="2070448at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005589">
        <property type="entry name" value="ArfA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03889">
        <property type="entry name" value="ArfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="81" mass="9280" checksum="7B195C633BA41638" modified="2008-04-29" version="1">MPKRPKQVPSIEHDSGRGKIKDNALKAIVTSELFKMRVEKPKKGKGSYKRKQKGHMLKGDAPFSWQLFLLALPILPIQYIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEZ8</accession>
    <name>B1KEZ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4435 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323496.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85149">
        <property type="protein sequence ID" value="ACA85149"/>
        <property type="gene ID" value="Swoo_0854"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0854"/>
    <dbReference type="eggNOG" id="ENOG502Z8GC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078431_1_0_6"/>
    <dbReference type="OMA" id="CCGHDLI"/>
    <dbReference type="OrthoDB" id="2011618at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029492">
        <property type="entry name" value="DUF4435"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14491">
        <property type="entry name" value="DUF4435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4435" evidence="1">
        <location>
            <begin position="26"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="31469" checksum="FF1A9FDC0683DA4A" modified="2008-04-29" version="1">MTSCLSQSAEEIVTEISMSESKNPWLVVEGDSDGVFFSTKRLHKSPNTIVALGWENVVGVISQVIEESITKAVFGFIDRDYREELGVVVDESYIVTTDFRDLEISLFESSSLHRLIVEYGSKFKLPLDSNEEVDLDEIKVKIYSIASKMGRLRYFSLKEGYNYPIKKLDFSKFIDQKTLELDESKLINQINAKSENKINSDLLNTILSAKLPTTLCDAKNICSGHDVVELLGLALKKVWGTNNSGEVAREKLESSFRIGYSNEEFSQTTMYKKLNALLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF43</accession>
    <name>B1KF43_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-polyprenyl-6-hydroxyphenol methylase</fullName>
            <ecNumber evidence="1">2.1.1.222</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.64</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiG</name>
        <name evidence="2" type="ordered locus">Swoo_2305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:31411"/>
            <dbReference type="Rhea" id="RHEA-COMP:9550"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:62729"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="EC" id="2.1.1.222"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.222" evidence="1"/>
    <dbReference type="EC" id="2.1.1.64" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2305"/>
    <dbReference type="EnsemblBacteria" id="ACA86584">
        <property type="protein sequence ID" value="ACA86584"/>
        <property type="gene ID" value="Swoo_2305"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2305"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042432_5_0_6"/>
    <dbReference type="OMA" id="RGTHDWE"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102208">
        <property type="term" value="F:2-polyprenyl-6-hydroxyphenol methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008689">
        <property type="term" value="F:3-demethylubiquinone-9 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="28490" checksum="85916302E35C03E0" modified="2008-04-29" version="1">MGIMATITHAFIGDSVQQDMQKEINVDPSEIAKFEKMAATWWDPEGEFKPLHRLNPLRLNYIDQTCGGVFGKRVLDVGCGGGILSESMARIGAKVDGLDMGAEPLDVARLHALEVGVEINYIQDTAESHRESHRESYDVITCMEMLEHVPSPRSVIQACADMVKPGGYVFFSTINRNLRAYVETILGAEYILKMLPIGTHDHKKFIKPSELISLAEHAELFCEDATGITFNPLTDTFSYTKNVDVNYMIATKKSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI4</accession>
    <name>B1KFI4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3901</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326489.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3901"/>
    <dbReference type="EnsemblBacteria" id="ACA88159">
        <property type="protein sequence ID" value="ACA88159"/>
        <property type="gene ID" value="Swoo_3901"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3901"/>
    <dbReference type="eggNOG" id="COG4551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144002_0_0_6"/>
    <dbReference type="OMA" id="FVCSRNQ"/>
    <dbReference type="OrthoDB" id="2062716at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016919">
        <property type="entry name" value="UCP029416_PTP"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029416">
        <property type="entry name" value="UCP029416_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="4">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="12635" checksum="E00CD7A40C30B392" modified="2008-04-29" version="1">MKNVLFICSRNQWRSPTGEQVWKNQAALSVRSAGTSPKARRTVNASDVQWADLIFVMEEKHKSRMKAQFTRLLAHKDIQVLDIPDEYQYMDTELVEIFKQSVGSYLELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI9</accession>
    <name>B1KFI9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326494.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3906"/>
    <dbReference type="EnsemblBacteria" id="ACA88164">
        <property type="protein sequence ID" value="ACA88164"/>
        <property type="gene ID" value="Swoo_3906"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3906"/>
    <dbReference type="eggNOG" id="COG2346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103526_3_0_6"/>
    <dbReference type="OMA" id="AYFLSGW"/>
    <dbReference type="OrthoDB" id="1697277at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="16060" checksum="82A1DE4B7E9D0C1D" modified="2008-04-29" version="1">MTPRSCEYGVGDNSYKMAGELAGLTQLVDEFYNNMDEVTGAKKIRDMHPEDLTESRQKLVYFLSGWLGGPRLYREHYGPISIPKSHQHLHIGLEESEAWLSCMEKAVAKQPYEAPFKLYLMEQLQVPAQRIRQVSSARKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL8</accession>
    <name>B1KFL8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326523.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3936"/>
    <dbReference type="EnsemblBacteria" id="ACA88193">
        <property type="protein sequence ID" value="ACA88193"/>
        <property type="gene ID" value="Swoo_3936"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3936"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022247_1_0_6"/>
    <dbReference type="OMA" id="CHFHHYW"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033856">
        <property type="entry name" value="Trp_halogen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011396">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="511" mass="57469" checksum="D5CDC94049F37FE3" modified="2008-04-29" version="1" precursor="true">MTKPITQVIIVGGGTAGWMSAASLGRYAQGKNLTITVIESSQLPTVGVGEATIPNIVEFNHSIGLNEIEFIKATQASFKLGIKFENWSQTSPSFFHPFSDYGLPINKVDFHQYVNRLAIENYKLEGHKLEGHNFKLEDYSFSSVLAQQGNFAQPHPNPPSPLADYSYAYHFDAGLYAELLKSHSLKMGVEHVDATIDQVNLHKNGFIESVSLHDGRVLEADLFIDCSGFKALLIEQAMKTGFDDWSEWLLCDTALAVQTKSTSSPNPYTRSIAHNSGWQWHIPLQHRTGNGYIFSSQFENKASAEQNLLTSLTGEPISQIRQFSFTPGRRKQIWNKNCFAVGLSSGFLEPIESTSISLIQSAIAKLLSFFPDTSFNEHDINEVNRLHNSELEHVRDFIILHYKLASGIDSPFWQYCQEMRVPETLSHKIDVYRSQGHIILRENESFEAASWLTMYHAFGVLPNRYDPRVDAIPLETVKQNLAQMKHSIINAASQSVSHQTFIDRHCKAVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM3</accession>
    <name>B1KFM3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326528.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3941"/>
    <dbReference type="CAZy" id="GH20">
        <property type="family name" value="Glycoside Hydrolase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88198">
        <property type="protein sequence ID" value="ACA88198"/>
        <property type="gene ID" value="Swoo_3941"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3941"/>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007082_5_1_6"/>
    <dbReference type="OMA" id="TRQHLKF"/>
    <dbReference type="OrthoDB" id="727559at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycohydro_20b2" evidence="8">
        <location>
            <begin position="28"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20" evidence="7">
        <location>
            <begin position="172"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20" evidence="7">
        <location>
            <begin position="562"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="811" mass="91686" checksum="15A052A3FC717413" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN3</accession>
    <name>B1KFN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative manganese transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323546.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0905"/>
    <dbReference type="EnsemblBacteria" id="ACA85199">
        <property type="protein sequence ID" value="ACA85199"/>
        <property type="gene ID" value="Swoo_0905"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0905"/>
    <dbReference type="eggNOG" id="COG1914">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_640842_0_0_6"/>
    <dbReference type="OMA" id="MCMFGTT"/>
    <dbReference type="OrthoDB" id="416257at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="424" mass="46542" checksum="5765A0BD4102344B" modified="2008-04-29" version="1" precursor="true">MEKLYSPNSNLNASLLTRSRYFLAALGPGLLMAAAAIGASHLVSSTRAGAEFGWQLAWVILAVNLLKYPFFAAGARYTAATGESLLHGYLKQGRGYLLLFSGLNTLAAIASTAGVTMLTAAMLTLFIPLSIDLLAFIVLIASLTILILGHYTLLDKLTKIIMLALTVSTLAAVALAFNIPPVINPDFISQSPWQWANIGFLVAMMGWMPAPIEVSVWNSLWLLEKQKSQLISKEQAIFDFNFGYLITALLAVTFLALGSLVMHGSGEQFSPSGVKFASQLITLYSQVLGEQTRYLIGAVALLCIFSTTVTVIDGYSRTLNMSWQLLRNQQYSNRRLTIIMLMISALGLAIVLFFKGALLPLLEIVMTLAFMTTIVFAWLNYKLMTSDKLPEQDRYGKKMKGLSALGMFYLLSFVCLFIYSIIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ1</accession>
    <name>B1KFQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323564.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0924"/>
    <dbReference type="EnsemblBacteria" id="ACA85217">
        <property type="protein sequence ID" value="ACA85217"/>
        <property type="gene ID" value="Swoo_0924"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0924"/>
    <dbReference type="eggNOG" id="COG0412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_1_0_6"/>
    <dbReference type="OMA" id="CATCFFP"/>
    <dbReference type="OrthoDB" id="1889569at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="17"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="245" mass="27434" checksum="955E6DBCABDB3FA0" modified="2008-04-29" version="1">MMVTHEVHDIPTATGVMRTYLYRPDEEGPFPTILFYSEIFQQTEPIARAATIMAGHGFVVLVPEVFHELNQIGTVLAYDDAGKDKGNEDKFAKPLESHDSDTEALVQFARSQPFCTSQVGSMGVCIGGHLAYRAAINPDISAAFCLYATDIHSSTLPSEEGNDSLSKTADIQGELVMVWGKQDPHVSTEGRKRVYEQLESTQRRFTWLEVNAQHAFMRDGESRYDPALAIQMYLQAVAFFHRILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV8</accession>
    <name>B1KFV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DSBA oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0981"/>
    <dbReference type="EnsemblBacteria" id="ACA85274">
        <property type="protein sequence ID" value="ACA85274"/>
        <property type="gene ID" value="Swoo_0981"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0981"/>
    <dbReference type="eggNOG" id="COG3917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_617856_0_0_6"/>
    <dbReference type="OMA" id="WGQDRLW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="1">
        <location>
            <begin position="249"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="441" mass="51228" checksum="87E43587BAB5C131" modified="2008-04-29" version="1">MAIISVIKSYLISYLARGISSECWLSVKRTLHEVKRRLLKREHRFEIFIDIQDPYSYLLLQALVEFRTHYFSHLKSVFHFYPVNSRDIEAFPELVLWKANAFDDACYLAERYGFDFPANEPMRSDGEVRCAQAALFKAENSLTACLAVFRHFWQEEAELDSGSLDCYSLLDARLKTNNHYLNRRGHYMGGMLYYAGEWYWGVDRLAHLERRLIELKGLNIQALFDKSGLAFKDFKERKAKVCEHLSPLTLYFSIRSPYSHLGLEQAVRVSEHYGVNLVVKPVLPMVMRGLSVPSKKKLYIFHDTKREAMKLGIRYGFVADPLGKGVEHCYALFDYACRQGREVEYLLAYSRAVNTLGVNSQSLSGLKKIVQMAGLDWQEAKTELNSEVWRDWAKLNLEELYALGLWGVPSFSYKECQVWGQDRLVRIEDEILEDIKRAEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG80</accession>
    <name>B1KG80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326547.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88217">
        <property type="protein sequence ID" value="ACA88217"/>
        <property type="gene ID" value="Swoo_3960"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3960"/>
    <dbReference type="eggNOG" id="ENOG5032VQV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078185_0_0_6"/>
    <dbReference type="OMA" id="YPDSSCQ"/>
    <dbReference type="OrthoDB" id="1234968at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="34414" checksum="5E2AE6D225BAB5EC" modified="2008-04-29" version="1" precursor="true">MIFKSLLFTGVLALFNNTVANQEVKMEELRYLAAFNTNKSYCFSTVNGVPTSRNTFTSSGTISTGFNITSIIENGTNSMSVQMVALEAPDNLDLELDSSCELLISANSKKNRYNIASVIATADDKLQPTGRSTPEYSGNNHVGPVKEDFMHDSYLYEVQRTFEAKGIPQWKWTTATSFVDTKENVQKLKDKYLDIWLLFKNEDLDIIKHESQISNQEMAQTEGMSPDEWWDTLSVKEMLSSDKSIIPIRWDEYELKTYNKGRLVRFEDMDGDSPLRVEYNDRIKTYNPYFSLINGKLVITR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG7</accession>
    <name>MDH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Malate dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mdh</name>
        <name type="ordered locus">Swoo_1002</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323642.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KGG7"/>
    <dbReference type="SMR" id="B1KGG7"/>
    <dbReference type="STRING" id="392500.Swoo_1002"/>
    <dbReference type="EnsemblBacteria" id="ACA85295">
        <property type="protein sequence ID" value="ACA85295"/>
        <property type="gene ID" value="Swoo_1002"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1002"/>
    <dbReference type="eggNOG" id="COG0039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047181_1_0_6"/>
    <dbReference type="OMA" id="MGWTSQA"/>
    <dbReference type="OrthoDB" id="870724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01516">
        <property type="entry name" value="Malate_dehydrog_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023958">
        <property type="entry name" value="Malate_DH_type1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="chain" id="PRO_1000191598" description="Malate dehydrogenase">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01516"/>
        </source>
    </evidence>
    <sequence length="311" mass="31968" checksum="FAED01F3335D6D7C" modified="2008-04-29" version="1">MKVAVLGAAGGIGQALALLLKTQLPADSKLSLYDIAPVTPGVAVDLSHIPTAVEVKGFAGQDPSPALEGADVVLISAGVARKPGMDRSDLFNINAGIVRNLVEKCAATCPKALIGIITNPVNTTVAIAAEVLKAAGVYDKNRLFGVTTLDVIRSETFVAEAKGLNVADVNVNVIGGHSGVTILPLLSQIEGVSFSDEEVAALTTRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVRGLQGEANVVECAYVDGGSEHAEFFAQPILLGKNGVEKVLAYGDVSEFEANARDAMLDTLNADIKLGVEFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK2</accession>
    <name>B1KGK2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1037</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323676.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1037"/>
    <dbReference type="EnsemblBacteria" id="ACA85330">
        <property type="protein sequence ID" value="ACA85330"/>
        <property type="gene ID" value="Swoo_1037"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1037"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_15_6"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="281"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="670"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="793" mass="89595" checksum="3C20EF7DB360B823" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGQ6</accession>
    <name>B1KGQ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2498</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 7">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325116.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2498"/>
    <dbReference type="EnsemblBacteria" id="ACA86775">
        <property type="protein sequence ID" value="ACA86775"/>
        <property type="gene ID" value="Swoo_2498"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2498"/>
    <dbReference type="eggNOG" id="COG0372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025068_2_1_6"/>
    <dbReference type="OMA" id="LTYCGYD"/>
    <dbReference type="OrthoDB" id="1412360at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011278">
        <property type="entry name" value="2-MeCitrate/Citrate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01800">
        <property type="entry name" value="cit_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="374" mass="41424" checksum="6C9402E4BD2F10AF" modified="2008-04-29" version="1">MVDKKLSGAGLRGQSAGETSLCTVGKSGSGLTYCGYDVADLADNATFEEVAYLLFNGELPNRAQLDAYKTELMAMRDLPQALKEVLQRIPADAHPMDVMRTGCSFLGNLEPENDFSEQNQAANRLLAAFPAIMCYWYKFSHDGVEINCVTDEDSLGGHFLHLLNGKTPSEQHRRVMDVSLILYAEHEFNASTFTARVCASTLSDMFSCITGAIGTLRGPLHGGANEAAMDMIQKFSSPADAKTQMAGMLERKEKIMGFGHAIYRTSDPRNVIIKAWSEKLAQENGDTSLYDISVACEEFMWDTKKLFCNADFFHASAYHFMGIPTKLFTPIFVCSRLTGWAAHVMEQRSNNRIIRPSADYTGSEPRMVKPIAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT3</accession>
    <name>B1KGT3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein, VC_A0111 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325143.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2525"/>
    <dbReference type="EnsemblBacteria" id="ACA86802">
        <property type="protein sequence ID" value="ACA86802"/>
        <property type="gene ID" value="Swoo_2525"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2525"/>
    <dbReference type="eggNOG" id="COG3520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048238_0_0_6"/>
    <dbReference type="OMA" id="RFQNDGE"/>
    <dbReference type="OrthoDB" id="1688251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010732">
        <property type="entry name" value="T6SS_TssG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35564">
        <property type="entry name" value="PTHR35564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06996">
        <property type="entry name" value="T6SS_TssG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03347">
        <property type="entry name" value="VI_chp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="335" mass="38286" checksum="A19039281CD20C56" modified="2008-04-29" version="1">MGYSDRSTATDLIDGGDELIIPDEISSYNFFQLVELIHKLDGNNPEGQEWESLGNMFFSANPSLGFPASDVTRIERHPKERVQIETTFLGLNGAQSPLPSYMLEELLHDDSNIKRDFLDFFNNRLIALFYRAWRKYRYYIRFQDNAVDNFSSQVFALVGLANEDVRGETPINWCKMLAYAGMLAGRSRSPQAVAGIVAHCFDLENVSIREWEFRHVEIPEPQRCQLGKFNSQLGVDTVLGEKVGDITGKFVLCIKDLSLHRFQDFLPSGKEFMPLCKVMEVILREQMAFDFELTLKTDEVPLLRLGEEKGGQLGWSSFLGQAEIEKQHVLIQIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGX4</accession>
    <name>B1KGX4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2566</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325183.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2566"/>
    <dbReference type="EnsemblBacteria" id="ACA86843">
        <property type="protein sequence ID" value="ACA86843"/>
        <property type="gene ID" value="Swoo_2566"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2566"/>
    <dbReference type="eggNOG" id="ENOG502ZKS6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153246_0_0_6"/>
    <dbReference type="OMA" id="ISYTIEV"/>
    <dbReference type="OrthoDB" id="2052964at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025514">
        <property type="entry name" value="DUF4402"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14352">
        <property type="entry name" value="DUF4402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15464" checksum="0426727A5FE08809" modified="2008-04-29" version="1">MLSAVLFVSLVGQVGFNLIDPLQITETKSVHFGDILNQANVSCRMTLGSRTGDACIQSPSTLGMFRINSAGNADVQIRVYSADSQDIDFTPLLENETSEQNYQLTKDEFEFNVGGELMIKRAMEKGQHQITYTVEVNYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH33</accession>
    <name>B1KH33_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326674.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88345">
        <property type="protein sequence ID" value="ACA88345"/>
        <property type="gene ID" value="Swoo_4089"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4089"/>
    <dbReference type="eggNOG" id="ENOG50345G7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1309415_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767348" evidence="1">
        <location>
            <begin position="28"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23613" checksum="DE596ACD593FCC58" modified="2008-04-29" version="1" precursor="true">MKSTTLLRPLKLCAILSMIFVTSSAVANGYVTQPYSDMCDSTYAINPDSFDRKSKDENQFIFSDRYCITEMVARRAVDISTLPTLKTVRGIAKRYNKVYSTLENTDEKITFVDLFLHRASQQHHISLDHIRSSEESIQLIISSASVSQKSVSGYNLSLFQDDNIDSEISNAYSKHLSNISDITSSSDVIDMVNYVLEASSKKSLEVQTHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH58</accession>
    <name>B1KH58_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4114</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326699.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4114"/>
    <dbReference type="EnsemblBacteria" id="ACA88370">
        <property type="protein sequence ID" value="ACA88370"/>
        <property type="gene ID" value="Swoo_4114"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4114"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_15_0_6"/>
    <dbReference type="OMA" id="NENWGIR"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="50"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="247"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="703" mass="78572" checksum="C522C6931D61BC28" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH77</accession>
    <name>B1KH77_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85385">
        <property type="protein sequence ID" value="ACA85385"/>
        <property type="gene ID" value="Swoo_1092"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1092"/>
    <dbReference type="eggNOG" id="ENOG502ZZ0G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1980060_0_0_6"/>
    <dbReference type="OMA" id="GWAEPFL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="14377" checksum="5D0B483A88338F74" modified="2008-04-29" version="1">MRLLNKLLTVSMKLDRTKELIHGSINKSEPYEALVHVLESAIELVQIPDNDFFWSYWEDAADATKEITKFLNMAKSYALPERAEVGVMFAPTGPLQELSLSSGWAEPFLKVAEKYDQVEGLLWPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH79</accession>
    <name>B1KH79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323733.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1094"/>
    <dbReference type="EnsemblBacteria" id="ACA85387">
        <property type="protein sequence ID" value="ACA85387"/>
        <property type="gene ID" value="Swoo_1094"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1094"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_5_1_6"/>
    <dbReference type="OMA" id="AWCPYCN"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764473" evidence="1">
        <location>
            <begin position="23"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="35"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="212" mass="23520" checksum="48D03BC5089273D3" modified="2008-04-29" version="1" precursor="true">MFTKTLNVLLLCLTSLSLIATAKPIASNDLNVMPLMNGQMLPSAKVANLKGETLDLLSLTQGKPSIIFFYRGGWCPFCNSQMGQLKEIEPKLIEMGFQLIGISPDSPEKLNASMIDQKLSYTLLSDTNLNAMQAFGLAYYTSEKTTERYMKKLKLDELLKVTPQGDKRLVLPVPAIYISDGTGLIHFQYVNPNFRVRPAPQLIEMAASLVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHB6</accession>
    <name>B1KHB6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putrescine-binding periplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the activity of the bacterial periplasmic transport system of putrescine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein PotD/PotF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323770.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1131"/>
    <dbReference type="EnsemblBacteria" id="ACA85424">
        <property type="protein sequence ID" value="ACA85424"/>
        <property type="gene ID" value="Swoo_1131"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1131"/>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_1_4_6"/>
    <dbReference type="OMA" id="YANPNPK"/>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764477" description="Putrescine-binding periplasmic protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR019574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="366" mass="40364" checksum="680E42C58C720C77" modified="2008-04-29" version="1" precursor="true">MKFFKKITTLALIGAGVLASTNVMAEEVVRVYNWSDYIAEDTLANFEKETGIRVIYDVFDSNEVVEAKLLSGRSGYDLVVPSNNFLAKQIKAGAFQKLDVAQLSNHKNLKADLMKQLEAADPGNEYSVPYLWGTTGIGYNEGKVKEILGEDAPTDSLELLFNPKYAEKLSKCGLSMLDSADEMLPMALVYLGLDPNSNSKADYKKAGEVLDKVRPFVTYFHSSRYITDLANGDICVAFGYSGDVFQAAARAEEAENGQVIGYSIPKEGANLWFDMLAIPADAANVKNAHTFINYILRPEVIAPITDYVAYANPNAAAETLVDKEILSDPAIYPTPEVLKRLYVADVRPMKAQRAMTRVWTKVKSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHB8</accession>
    <name>B1KHB8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323772.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1133"/>
    <dbReference type="EnsemblBacteria" id="ACA85426">
        <property type="protein sequence ID" value="ACA85426"/>
        <property type="gene ID" value="Swoo_1133"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1133"/>
    <dbReference type="eggNOG" id="COG1176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_18_3_6"/>
    <dbReference type="OMA" id="YPIAYGM"/>
    <dbReference type="OrthoDB" id="1488093at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="33674" checksum="754FD400C1837465" modified="2008-04-29" version="1" precursor="true">MKKPLTFKLPKGQCWTIGVPYFWLLLFFALPFAIVLKISLSTAAISIPPYESLFNYADESLQILLNLGNYLLIFDDSLYLYAYLGSLKMAFITTLGCLLIGYPMAYAIARAPKEKQTLLILLVMLPSWTSFLIRVYAWMGILSNNGVINNILLWSGVISEPIQMLNTNFAVYIGIIYSYLPFMILPLYATLSQLDGSLLEAASDLGSRSLNTFWKITLPLSKGGVIAGSMLVFIPVVGEFVIPELLGGPDSLMIGKVLWQEFFNNRDWPVASALAIVMLGLLIIPITLFHRYQSRSMEKEV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH0</accession>
    <name>CMOB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA U34 carboxymethyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmoB</name>
        <name type="ordered locus">Swoo_2578</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-hydroxyuridine(34) in tRNA + carboxy-S-adenosyl-L-methionine = 5-carboxymethoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:52848"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="Rhea" id="RHEA-COMP:13383"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
            <dbReference type="ChEBI" id="CHEBI:136879"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325195.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHH0"/>
    <dbReference type="SMR" id="B1KHH0"/>
    <dbReference type="STRING" id="392500.Swoo_2578"/>
    <dbReference type="EnsemblBacteria" id="ACA86855">
        <property type="protein sequence ID" value="ACA86855"/>
        <property type="gene ID" value="Swoo_2578"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2578"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052665_0_0_6"/>
    <dbReference type="OMA" id="CEWRSDF"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01590">
        <property type="entry name" value="tRNA_carboxymethyltr_CmoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010017">
        <property type="entry name" value="CmoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027555">
        <property type="entry name" value="Mo5U34_MeTrfas-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08003">
        <property type="entry name" value="Methyltransf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00452">
        <property type="entry name" value="TIGR00452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000201313" description="tRNA U34 carboxymethyltransferase">
        <location>
            <begin position="1"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01590"/>
        </source>
    </evidence>
    <sequence length="330" mass="37637" checksum="33865CFEC3C377EC" modified="2008-04-29" version="1">MISFSSFYKKIADSSLQHWLETLPAILGQWQREHKHGTLPKWEKVLNKLHYPNPDTLELKDSVTIGSGQQLTSGEQQKLENLLRIFQPWRKGPFSVHGINIDTEWRSDWKWERILPHLSPLNNRTVLDVGCGSGYHMWRMLGEGANHVVGIDPSTLFLCQFEAIKRLAGEEQPIHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRTGGELVLETLVIDGDENTVLVPEDRYGKMNNVWFLPSAAALALWLKKADFVDIRCVDIDVTSLAEQRSTDWMPNESLVDYLDPSNIDLTVEGYPAPKRATFIATKNQPNKDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH7</accession>
    <name>B1KHH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SrpA-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325202.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2585"/>
    <dbReference type="EnsemblBacteria" id="ACA86862">
        <property type="protein sequence ID" value="ACA86862"/>
        <property type="gene ID" value="Swoo_2585"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2585"/>
    <dbReference type="eggNOG" id="COG3064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_629889_0_0_6"/>
    <dbReference type="OMA" id="ATINKMR"/>
    <dbReference type="OrthoDB" id="989412at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021973">
        <property type="entry name" value="SprA-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12118">
        <property type="entry name" value="SprA-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="435" mass="45448" checksum="57F6BABBD8632DAE" modified="2008-04-29" version="1">MLGVNVSSALSGGSDNLSPTKRLSGISYSTSVSTVTVSPNSTSPSSLSTKPTLKGTLSSNHAPPTVEVNNASLNANTAADLSVQIGAELGAESTLTAELPPVSSSLPPSSFSLTQGALSINGLVSTSTNISSSALQQGGELPASQITGVKEPQLEPDTSFSPVTGADASPVFSGQESASKPSLEPSQERPEHIDEGSKPVFNPFESTQEEDKASEESSAKALVLEQKILAELAKRDAEVRSHEQAHATVGGVHAQSPQLSYEQGSDGRRYAVDGEVSIDISTVPGNPLATINKMRQVYAAAMAPTDPSMADIRVAAEAMRKLNQARAELAEQRVNDAPSIEEMAPLLGAQSSIDQTPIFDPPKFTTAGDVDETGAITKPQLDEVNPVSDSVDKINSQLSAQSMTLETDSHHYLTETVSERYEPRSSVASSLSFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHK5</accession>
    <name>B1KHK5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Intracellular proteinase inhibitor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325230.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2613"/>
    <dbReference type="EnsemblBacteria" id="ACA86890">
        <property type="protein sequence ID" value="ACA86890"/>
        <property type="gene ID" value="Swoo_2613"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2613"/>
    <dbReference type="eggNOG" id="ENOG5032Q56">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121450_0_0_6"/>
    <dbReference type="OMA" id="QYRSGMT"/>
    <dbReference type="OrthoDB" id="1843457at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020481">
        <property type="entry name" value="Intracell_prot_inh_BsuPI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038144">
        <property type="entry name" value="IPI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12690">
        <property type="entry name" value="BsuPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BsuPI" evidence="1">
        <location>
            <begin position="85"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="196" mass="21466" checksum="561EAB4F5A5E6CC9" modified="2008-04-29" version="1" precursor="true">MNNHMLLASLAIVSLTACSQSNLDNKLDSVAKTQPVEADMPKEQKVKVVVLAKDDVDITKLQKQHAEGKMTKGLLTGELDATLDNGLLVSLKILNNQPYGVPIQYRSGMTADLQLLDPMGDKVWAWSNEMMFTQAIRDTVIPSGKEMTVKFKIPQTVMSQLKGKGYTIKAIYAGQAIESKELAMGDISLSLNDILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHN3</accession>
    <name>B1KHN3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RecBCD enzyme subunit RecC</fullName>
            <ecNumber evidence="6">3.1.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Exonuclease V subunit RecC</fullName>
            <shortName evidence="6">ExoV subunit RecC</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Helicase/nuclease RecBCD subunit RecC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recC</name>
        <name evidence="8" type="ordered locus">Swoo_2641</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.</text>
            <dbReference type="EC" id="3.1.11.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RecC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.5" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325258.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2641"/>
    <dbReference type="EnsemblBacteria" id="ACA86918">
        <property type="protein sequence ID" value="ACA86918"/>
        <property type="gene ID" value="Swoo_2641"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2641"/>
    <dbReference type="eggNOG" id="COG1330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007513_0_0_6"/>
    <dbReference type="OMA" id="SFDLMQY"/>
    <dbReference type="OrthoDB" id="1320159at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009338">
        <property type="term" value="C:exodeoxyribonuclease V complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01486">
        <property type="entry name" value="RecC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006697">
        <property type="entry name" value="RecC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041500">
        <property type="entry name" value="RecC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17946">
        <property type="entry name" value="RecC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000980">
        <property type="entry name" value="RecC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01450">
        <property type="entry name" value="recC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecC_C" evidence="7">
        <location>
            <begin position="883"/>
            <end position="1114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1190" mass="134889" checksum="0E83432ABFA5174B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHW4</accession>
    <name>B1KHW4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326771.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4186"/>
    <dbReference type="EnsemblBacteria" id="ACA88442">
        <property type="protein sequence ID" value="ACA88442"/>
        <property type="gene ID" value="Swoo_4186"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4186"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_26_6"/>
    <dbReference type="OMA" id="DATKEIH"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="247"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="526" mass="57151" checksum="A1F3AFE28BBA4F1C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY9</accession>
    <name>PRIB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Primosomal replication protein N</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">priB</name>
        <name type="ordered locus">Swoo_4211</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds single-stranded DNA at the primosome assembly site (PAS).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PriB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326795.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHY9"/>
    <dbReference type="SMR" id="B1KHY9"/>
    <dbReference type="STRING" id="392500.Swoo_4211"/>
    <dbReference type="EnsemblBacteria" id="ACA88467">
        <property type="protein sequence ID" value="ACA88467"/>
        <property type="gene ID" value="Swoo_4211"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4211"/>
    <dbReference type="eggNOG" id="COG2965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166075_0_0_6"/>
    <dbReference type="OMA" id="CQMPVII"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00720">
        <property type="entry name" value="PriB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023646">
        <property type="entry name" value="Prisomal_replication_PriB"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003135">
        <property type="entry name" value="Primosomal_n"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04418">
        <property type="entry name" value="PriB_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0639">Primosome</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000132635" description="Primosomal replication protein N">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="SSB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00720"/>
        </source>
    </evidence>
    <sequence length="101" mass="11370" checksum="241F45122515E368" modified="2008-04-29" version="1">MATNHLVLSGTITRSRSFHSPSGIAHSVIMLEHKSQCYEAEMLRNVYCQMQVILSGERFESVTDKLKIGVDIEVQGFIALQQSRNGQNRLVLHAENVELKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI37</accession>
    <name>B1KI37_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Conserved hypothetical radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323861.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1222"/>
    <dbReference type="EnsemblBacteria" id="ACA85515">
        <property type="protein sequence ID" value="ACA85515"/>
        <property type="gene ID" value="Swoo_1222"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1222"/>
    <dbReference type="eggNOG" id="COG1242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060920_0_0_6"/>
    <dbReference type="OMA" id="NAGFTCP"/>
    <dbReference type="OrthoDB" id="979208at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005911">
        <property type="entry name" value="YhcC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="PTHR11135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF1">
        <property type="entry name" value="PTHR11135:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01091">
        <property type="entry name" value="uncharacterized_CHP01210-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01212">
        <property type="entry name" value="TIGR01212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="17"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="312" mass="34749" checksum="941010921B6D8AEA" modified="2008-04-29" version="1">MGLDQYVNTFGVACKQRFGEKLKKLTIDAKFTCPNRDGTLGRGGCTYCNVASFSYEHGTELSIPEQLNKGRERFAGRTSKYIAYFQAYTSTYDEYKVLKAKYDEAIIDPDIVGLCVGTRPDCVSDDVIELLAGYQARGIDVWLELGLQSASDKTLKRINRGHTLADYLDTVTRARAKGIKVCTHLILGLPGEEHQDYLNSLHAVLQAGVDGLKLHPLHIVEGSTMAKAWRSSRISLLSMEDYAYSVGEMIRYTPKEIIFHRVTAYAKKPILLAPDWCAYRWNGLVAIVDDLKAKGGQGSYLISKLKMSSKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI48</accession>
    <name>B1KI48_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD assembly factor SdhE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1234</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SdhE FAD assembly factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1234"/>
    <dbReference type="EnsemblBacteria" id="ACA85526">
        <property type="protein sequence ID" value="ACA85526"/>
        <property type="gene ID" value="Swoo_1234"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1234"/>
    <dbReference type="eggNOG" id="COG2938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103054_2_2_6"/>
    <dbReference type="OMA" id="FEHEYDT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="SSF109910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9777" checksum="2DE30BDC1A963B74" modified="2008-04-29" version="1">MSEPMNIARVRWACRRGMLELDVLFQPFVEKHYEQMSVEDKHIFVRLLEGEDPVLFAWFMGHEKCADPELAKMVIRVRGRDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC0</accession>
    <name>B1KIC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">17 kDa surface antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2695"/>
    <dbReference type="EnsemblBacteria" id="ACA86971">
        <property type="protein sequence ID" value="ACA86971"/>
        <property type="gene ID" value="Swoo_2695"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2695"/>
    <dbReference type="eggNOG" id="COG3133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090265_5_0_6"/>
    <dbReference type="OMA" id="VRYITQQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008816">
        <property type="entry name" value="Gly_zipper_2TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05433">
        <property type="entry name" value="Rick_17kDa_Anti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rick_17kDa_Anti" evidence="1">
        <location>
            <begin position="65"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="17265" checksum="A662B4B09FC4368A" modified="2008-04-29" version="1">MIMLKPWITCLAIVCLFIGVISPIEAGYKRNQAVAVEQVQYGSVVSVRNITQKQLVEDRNQGWKTFGGALIGGVVGHQFGGGSGQDVATVLGALIGAGVGNRYGDNSYYQELSLVELMIKQEDGKQVMIIQDLDPGMIFNAGDEVRVVYLQGSVRVDIAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK0</accession>
    <name>B1KIK0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">RNA polymerase sigma-54 factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_4240</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the sigma-54 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326823.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4240"/>
    <dbReference type="EnsemblBacteria" id="ACA88496">
        <property type="protein sequence ID" value="ACA88496"/>
        <property type="gene ID" value="Swoo_4240"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4240"/>
    <dbReference type="eggNOG" id="COG1508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020569_0_1_6"/>
    <dbReference type="OMA" id="VTTQKFM"/>
    <dbReference type="OrthoDB" id="1906842at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00717">
        <property type="entry name" value="SIGMA54_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="9 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="13">
        <location>
            <begin position="135"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="12">
        <location>
            <begin position="334"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="56"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA88496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="493" mass="55724" checksum="8DD3007FF8C37365" modified="2008-04-29" version="1">MKASLQLKMGQHLTMTPQLQQAIRLLQLSSLELQQEIQQALDSNPLLELDEEQVDANADNSDVKNNSETDFSASVEKEADKDSSSLETSDALNQDSMPEDLPVDTTWDEVYTATPNSSSGAMRDDDLPFQGETCEGLYEHLEWQKNLTPFSDNDLAIATAIIDAIDERGYLTQSTDDILEAMGDPEIELDEVEAVLKRVQHFDPIGVAARDLSECLFIQLAQYANTTPHIDNARLLIKEHLDLIAGRDFRLLMRKTKLKEDDLRQAIELIQTLNPRPGLAINPSRDEYVIPDVTVIKKKGRWIVELNPDYMPKINVNQHYASMARSTKNQADSQFIRGHLQEAKWFIKSLESRNDTLLKVSNCIVKFQQGFFEYGEEAMKPMVLNDIAEEVEMHESTISRVTTQKYMHTPRGIFELKYFFSSHVGTDDGGECSSTAIRAFIKKLVAAENQQKPLSDSKMALLLAEQGIKVARRTIAKYREAMLIPPSNQRKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ3</accession>
    <name>B1KIQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326876.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88549">
        <property type="protein sequence ID" value="ACA88549"/>
        <property type="gene ID" value="Swoo_4294"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4294"/>
    <dbReference type="eggNOG" id="ENOG50316E1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_893992_0_0_6"/>
    <dbReference type="OrthoDB" id="1076123at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="311" mass="36506" checksum="8305A50601CDA71F" modified="2008-04-29" version="1">MLTSDKLAEAPREGEKAILGKTEIGFVRRGEAGLTPEERNFPFKCVLSQNVEYMDIGSSEIDHSIGLWVRIVCFMTLAWISMIALSYDPYDPYEPEFIWQAVTLFSSASFLLLCGGLCYYIFRRRRRTTVSFYRKRQKLVFKASSRAEPVEIDWGDVVPYLRPRRIRGVIGSSRIDMPGMSFCLAWYDSESQTLHTFYTSEFKLSMFVADEWRLMLRYMNGDDNNFANNYEPVATSAYFQEKRDKLWRDFRANKNKRLFTFSVRDMSVSYLSMTLFYFSHLIGWWRIPYLFTDFYLACAVTPFLPSDRSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIS2</accession>
    <name>B1KIS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323916.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1278"/>
    <dbReference type="EnsemblBacteria" id="ACA85570">
        <property type="protein sequence ID" value="ACA85570"/>
        <property type="gene ID" value="Swoo_1278"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1278"/>
    <dbReference type="eggNOG" id="ENOG5033D3F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_198021_2_0_6"/>
    <dbReference type="OMA" id="MNRLDYG"/>
    <dbReference type="OrthoDB" id="1998773at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021932">
        <property type="entry name" value="DUF3545"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12065">
        <property type="entry name" value="DUF3545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="61" mass="7290" checksum="8C4CC27C418F1DFD" modified="2008-04-29" version="1">MNRLDYGSALDAVVERPSRSRSSNKKRKWREIEALKEKHRLLKELQDIDKSFECELDNLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ00</accession>
    <name>B1KJ00_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1356</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323994.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1356"/>
    <dbReference type="EnsemblBacteria" id="ACA85648">
        <property type="protein sequence ID" value="ACA85648"/>
        <property type="gene ID" value="Swoo_1356"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1356"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_2_1_6"/>
    <dbReference type="OMA" id="RASILIK"/>
    <dbReference type="OrthoDB" id="1532186at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767108" evidence="2">
        <location>
            <begin position="23"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="49"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="387" mass="42507" checksum="D212CFE412F4BD31" modified="2008-04-29" version="1">MPAQTVSKLKWCTLFIIGLQLAACGDAPAPKQAMLPSVIVNTAKTEEIQSKTEIVGRTHASEDVVIKSQIQGQLLKRTFIEGDDIDKGDLLFEIDPSTFEAELAQHKAVLKQALASRDVAVMNWERGSRLLPDGMISAQDMDELTTRKLTTAAGVVQAEAAVKGSELQLSYTKIYAPISGRISNSKVSTGDIISSNSEMANLVQLQPMWVNFQVAERALINARESFAKAAKKEIEISDIIIGLRLPNGSMFSETGYVDFVSNRVDAATGTLPIRATFKNENKLMLPGMFVTLIIESPVKENALLIPQASVQEDQQGRFVMVLNDKDEVEKRIVELGERFGIDWRVLSGLKDGERIVVDGLQKIRPGIQVKAVEQEVIPFKESQTAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ31</accession>
    <name>B1KJ31_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325387.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2775"/>
    <dbReference type="EnsemblBacteria" id="ACA87051">
        <property type="protein sequence ID" value="ACA87051"/>
        <property type="gene ID" value="Swoo_2775"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2775"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_6"/>
    <dbReference type="OMA" id="NDFPMPM"/>
    <dbReference type="OrthoDB" id="1186478at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="26006" checksum="6759D5748FE9D6CF" modified="2008-04-29" version="1" precursor="true">MRTVMITGASSGIGKALAQHYDQLGWQVLACGRDQNRLMEVASSAQTIQTLAFDLTDKKQVEQISSDLPALDMLVFNAGDCRYIDNAMDFDAESFETIIQTNLISVAYGLKAWLKHMKKGGRVVFVSSSAELLALPRAEAYGASKAALSYLGESLSIDLAQHGLEVSIVRPGFVSTPLTAKNDFPMPMQVTSQQAAICIAKGLAKGKHHIDFPSSFTFLMKLLACLPFSVWRRLAIRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ37</accession>
    <name>B1KJ37_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lon N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325393.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2781"/>
    <dbReference type="EnsemblBacteria" id="ACA87057">
        <property type="protein sequence ID" value="ACA87057"/>
        <property type="gene ID" value="Swoo_2781"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2781"/>
    <dbReference type="eggNOG" id="COG2802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048359_3_1_6"/>
    <dbReference type="OMA" id="IDMVRTC"/>
    <dbReference type="OrthoDB" id="1474822at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="1">
        <location>
            <begin position="21"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="23768" checksum="829C2ED25A36B159" modified="2008-04-29" version="1">MKDYLVVNVDDIRTNFFAKRLPVMPLPLAILPGGIQRLKIFEPKYLSMIKVAIEGEGFVVCLHKKDSPYSSSNWGVWVKIIDFNLGEGSILLIDIQALTMVKLNTVERDACGLLTAALTPIQHWGFREISAETRELVESLREIFKSHISLRELYKKTHFYDANWVCARFIEVLPLSLNEKEKFIFDYSFDQIEGFLHTLIQGTVKNS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM7</accession>
    <name>3HAO_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="1">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="1">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="1">HAD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nbaC</name>
        <name type="ordered locus">Swoo_1408</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="1">Binds 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-HAO family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324046.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJM7"/>
    <dbReference type="SMR" id="B1KJM7"/>
    <dbReference type="STRING" id="392500.Swoo_1408"/>
    <dbReference type="EnsemblBacteria" id="ACA85700">
        <property type="protein sequence ID" value="ACA85700"/>
        <property type="gene ID" value="Swoo_1408"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1408"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095765_0_0_6"/>
    <dbReference type="OMA" id="NARKDYH"/>
    <dbReference type="OrthoDB" id="1591291at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000334">
        <property type="term" value="F:3-hydroxyanthranilate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="PTHR15497"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0223">Dioxygenase</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000134550" description="3-hydroxyanthranilate 3,4-dioxygenase">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00825"/>
        </source>
    </evidence>
    <sequence length="189" mass="21866" checksum="7F58E64EF3265606" modified="2008-04-29" version="1">MSKLAAFNFQQWIDEHQHLLKPPVGNVQIWENTDMMVTVVGGPNQRTDFHDDPVEEFFYQLKGDMVLKIIEEGKCHDLFIREGDIFFLPPHVRHSPQRPMPGSIGLVIEPKRPEGAKDAFEWYCFKCDGLVHRVEVLLKSIVRDLPPIYQAFYQDEQARTCPQCGELHPGKEPPQGWVTLLENKEQDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJN1</accession>
    <name>B1KJN1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1412</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324050.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1412"/>
    <dbReference type="EnsemblBacteria" id="ACA85704">
        <property type="protein sequence ID" value="ACA85704"/>
        <property type="gene ID" value="Swoo_1412"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1412"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_1_1_6"/>
    <dbReference type="OMA" id="SARWILN"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764970" evidence="5">
        <location>
            <begin position="27"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="53"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="281"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="847" mass="90410" checksum="E6BB3DB678E7409A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR1</accession>
    <name>B1KJR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H dehydrogenase (Quinone)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324080.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1442"/>
    <dbReference type="EnsemblBacteria" id="ACA85734">
        <property type="protein sequence ID" value="ACA85734"/>
        <property type="gene ID" value="Swoo_1442"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1442"/>
    <dbReference type="eggNOG" id="COG2249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058643_0_1_6"/>
    <dbReference type="OMA" id="QHRSEVN"/>
    <dbReference type="OrthoDB" id="1143659at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="205" mass="23458" checksum="CDB9F1095B58DE13" modified="2008-04-29" version="1">MPDERKKILVLFAHPSQERSEVNKPLFTECQQHGDVTCIDLYREYPTFHIDIDKEQQRLVEHDVIIFMFPLYWYSTPAILKQWQDLVLEYGFAYGTNGNALKGKTFLCAISAGGSEDAYQEVGYNHFSIRELLQPLEQTASLTGMEYLAPFVLFGSRSAVEENRVHEHINQMHQLLNALSNNKLDLAQAKSLPLLNKNLATLIQA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR3</accession>
    <name>Y1444_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0178 protein Swoo_1444</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1444</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0178 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324082.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJR3"/>
    <dbReference type="STRING" id="392500.Swoo_1444"/>
    <dbReference type="EnsemblBacteria" id="ACA85736">
        <property type="protein sequence ID" value="ACA85736"/>
        <property type="gene ID" value="Swoo_1444"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1444"/>
    <dbReference type="eggNOG" id="COG1671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106619_2_1_6"/>
    <dbReference type="OMA" id="CPVKDEI"/>
    <dbReference type="OrthoDB" id="1890924at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00489">
        <property type="entry name" value="UPF0178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003791">
        <property type="entry name" value="UPF0178"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35146">
        <property type="entry name" value="PTHR35146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02639">
        <property type="entry name" value="DUF188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000126215" description="UPF0178 protein Swoo_1444">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00489"/>
        </source>
    </evidence>
    <sequence length="151" mass="16475" checksum="AD492E797DECBD51" modified="2008-04-29" version="1">MKIWVDADACPGVIKEILFRVADRAKVEVTLVANHSMRIPPSRYINMVTVPSGFDVADDEIVKRLDAGDLVITADIPLASEVIDKGGVALNPRGELYTEQNIKSILNMRDFMDTMRASGVQTGGPAAIGASEKQAFGNQLDRFVTKHHKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW2</accession>
    <name>B1KJW2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">C4-dicarboxylate transporter/malic acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2874</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325485.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2874"/>
    <dbReference type="EnsemblBacteria" id="ACA87149">
        <property type="protein sequence ID" value="ACA87149"/>
        <property type="gene ID" value="Swoo_2874"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2874"/>
    <dbReference type="eggNOG" id="COG1275">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075737_1_0_6"/>
    <dbReference type="OMA" id="MIYRFMF"/>
    <dbReference type="OrthoDB" id="1600064at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="322" mass="35198" checksum="D7AFC0300E12558D" modified="2008-04-29" version="1" precursor="true">MKSSFKKISHHASKLPSPMAGLALAIASLGWAWENMLPGMHGRGQLISATVAAIMLMTLVIKFVLHPTILKQELSHPVVGSVIPTFAMGLMVVSNALGLYLPRLGLSLWLASIAIHLVFLAMFIYFRAIDFKLEHMVPSWFVPPIGIIVAAVTFPGVQYQWLANATLNFGMTCYLIMLPIMLYRLIFCAPIAEAAKPTIAIMAAPASLSLAGYLTVTSQPSLVIVALLLSIALLMTSVIYLAFFHLLRLPFSPGYAAFTFPMVIGATALFKAAHWLSHSFGESQFTDMIAHAAQLELFISTAVVLYVAYRYLSHYRSNILPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK30</accession>
    <name>B1KK30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylation site containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4409"/>
    <dbReference type="EnsemblBacteria" id="ACA88661">
        <property type="protein sequence ID" value="ACA88661"/>
        <property type="gene ID" value="Swoo_4409"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4409"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098637_3_0_6"/>
    <dbReference type="OMA" id="DTAKCWV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="166" mass="17225" checksum="46B77DF410D40C77" modified="2008-04-29" version="1" precursor="true">MKNQKGFTLIELVVVIIILGILAVTAAPKFINLQSDARASTLDGMKGALQGANTLLYSKAAIQGKEKDANTADANNVDTTGDGTADIKAVYGYVKADATEIAKVLESDGSEWTIVAPATGVASTADVEIIIHPADITPSATKQCFVEYTGATATDLPVYGTLSDDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK63</accession>
    <name>B1KK63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated CheW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4442</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327020.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4442"/>
    <dbReference type="EnsemblBacteria" id="ACA88694">
        <property type="protein sequence ID" value="ACA88694"/>
        <property type="gene ID" value="Swoo_4442"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4442"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048995_0_1_6"/>
    <dbReference type="OMA" id="IMICEFS"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024181">
        <property type="entry name" value="Chemotax_regulator_CheV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002867">
        <property type="entry name" value="CheV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="3">
        <location>
            <begin position="17"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="195"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="36215" checksum="15187F1607FE2EBD" modified="2008-04-29" version="1">MSELKKSEILTESGTNELEIIEFHLHKTLAGGGHKVCHYGINVAKVREVIRVPDTSDYPNAQSHMVGVFSLRDNLIPLVDLAGWLGIPTQNDLEHKVVIVTDFNRMINGFLIDSVRSIHRVSWEQVESPSQFLEAGEQDCVVAVVRREGHLIMVLDFEKIIADINPELSMDKYDVTLDKTVVINDEMLAKREAKTILIVDDSAFIRKMIENTLRTAGYNIITAKDGGDALEMLEEFERLAEEAGASVSEMVSGIISDVEMPRMDGLHLLKRLRDKPSYKTMPIVMFSSLMSEDNRGKALALGANDTITKPEIGRMVTMVDSFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC1</accession>
    <name>B1KKC1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324107.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1473"/>
    <dbReference type="EnsemblBacteria" id="ACA85761">
        <property type="protein sequence ID" value="ACA85761"/>
        <property type="gene ID" value="Swoo_1473"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1473"/>
    <dbReference type="eggNOG" id="ENOG50346X2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2059829_0_0_6"/>
    <dbReference type="OrthoDB" id="2170207at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764605" evidence="1">
        <location>
            <begin position="22"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="12998" checksum="441F9AC6885DD598" modified="2008-04-29" version="1" precursor="true">MDILRKVLLISLVFLVQNAEAKYFTDYSSGVTINRIHAHSGGGVTLHITGEVTNLDNCLVTERVHIRADLVGSKNLIAHAMMAFASGKKVGLHASGCEIIPFWGGTHLTPIINNLWVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF4</accession>
    <name>B1KKF4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324140.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1506"/>
    <dbReference type="EnsemblBacteria" id="ACA85794">
        <property type="protein sequence ID" value="ACA85794"/>
        <property type="gene ID" value="Swoo_1506"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1506"/>
    <dbReference type="eggNOG" id="ENOG5033MGE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190758_0_0_6"/>
    <dbReference type="OMA" id="DSAWHAW"/>
    <dbReference type="OrthoDB" id="1989612at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9256" checksum="54A6B01C4A775820" modified="2008-04-29" version="1" precursor="true">MWSKTFAALFGGCLISISLMLNLNYLLPLAVDIRLFVGLLISFPLWVGAMIWCYGSDSAWHAWGRCGGLLLVSISINTLFFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR1</accession>
    <name>B1KKR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ferredoxin-dependent glutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325614.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3007"/>
    <dbReference type="EnsemblBacteria" id="ACA87278">
        <property type="protein sequence ID" value="ACA87278"/>
        <property type="gene ID" value="Swoo_3007"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3007"/>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023342_0_0_6"/>
    <dbReference type="OMA" id="FVSDMSF"/>
    <dbReference type="OrthoDB" id="151647at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024188">
        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043578">
        <property type="entry name" value="GltB_archl_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500061">
        <property type="entry name" value="GOGAT_lg2_archl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006429">
        <property type="entry name" value="GOGAT_lg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZnF_CDGSH" evidence="6">
        <location>
            <begin position="9"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="ZnF_CDGSH" evidence="6">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="516" mass="55055" checksum="41548FC84B04DDF7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL04</accession>
    <name>RL28_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmB</name>
        <name type="ordered locus">Swoo_4560</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327135.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL04"/>
    <dbReference type="SMR" id="B1KL04"/>
    <dbReference type="STRING" id="392500.Swoo_4560"/>
    <dbReference type="EnsemblBacteria" id="ACA88810">
        <property type="protein sequence ID" value="ACA88810"/>
        <property type="gene ID" value="Swoo_4560"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4560"/>
    <dbReference type="eggNOG" id="COG0227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064548_3_1_6"/>
    <dbReference type="OMA" id="FEPNLHT"/>
    <dbReference type="OrthoDB" id="2062238at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000121689" description="50S ribosomal protein L28">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="78" mass="9073" checksum="77A0C4402E098FF0" modified="2008-04-29" version="1">MSRVCQVTGKKPMVGNNRSHAKNATRRRFLPNLQNHRFWLEGEKRFVKLRISTKGMRIIDKKGIEVVVAELRARGEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL99</accession>
    <name>B1KL99_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lytic transglycosylase catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0139"/>
    <dbReference type="CAZy" id="GH23">
        <property type="family name" value="Glycoside Hydrolase Family 23"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84440">
        <property type="protein sequence ID" value="ACA84440"/>
        <property type="gene ID" value="Swoo_0139"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0139"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065765_2_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="176"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="32983" checksum="F3990788959D3D78" modified="2008-04-29" version="1" precursor="true">MILASREVSLFRGMQILFVFLVTPHALSTQAADKPHYKASRSESGLVVTGQVNELASEPVGVKMLDNSSAQTINSSSTSLNRSTVPPKPVKRAQAASSRHVLDNSSAGKQYRLETTLDDRVKVYQYQDENGVAVFTDHAPGASEYQVILYDCYACRPDSDLDWKKMPLYSKRFDDLIQLAARNHQLEPALIRAVIHAESAFNVYAISKTGAMGLMQLMPETAKELGVKNAFKPAQNIDGGARYLAKMLKRFGGDIELACAAYNAGPTRVTEHKGIPPYPETIAYVERVKILLKRYQSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE7</accession>
    <name>B1KLE7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DegT/DnrJ/EryC1/StrS aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324218.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1586"/>
    <dbReference type="EnsemblBacteria" id="ACA85872">
        <property type="protein sequence ID" value="ACA85872"/>
        <property type="gene ID" value="Swoo_1586"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1586"/>
    <dbReference type="eggNOG" id="COG0399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033332_2_1_6"/>
    <dbReference type="OMA" id="RFWATQA"/>
    <dbReference type="OrthoDB" id="1722208at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026385">
        <property type="entry name" value="AminoTrfase_NHT_00031"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04181">
        <property type="entry name" value="NHT_00031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="42377" checksum="19E179474C054822" modified="2008-04-29" version="1">MSSLVKFIRETYQTNEFIPLHAPTFAGNEQAYVAETITSTFVSSVGKFVTDFEQKIEAFTQSPKAIATSSGSSALHTALYMAGVQSGDLVITQSLTFVATCNALYHMGAAPIFVDISTVSLGLSPQAVQTYLEEYGLLNEEGLCIHKETKQTIKAVMPMHTFGHPVELDELVLICQQWNLVLIEDAAESLGSRYKEKHTGTIGEFAALSFNGNKIITTGGGGVLLTNNQANGIRAKHITTTAKVPHPYEFYHDEAGFNYRMPNLNAALGCAQMESLPLFIEQKRALAMHYNSFFDGGELLFVQEPSYAKSNYWLNAVICPNLHSRDKLLKLTNDSGVMTRPVWQLMHRLPMFKDALRGSLQHSEWFEERLVNLPSSPINTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI0</accession>
    <name>B1KLI0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Flagellar motor switch protein FliG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_1619</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3 12">Cell inner membrane</location>
            <topology evidence="3 12">Peripheral membrane protein</topology>
            <orientation evidence="3 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the FliG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324251.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1619"/>
    <dbReference type="EnsemblBacteria" id="ACA85905">
        <property type="protein sequence ID" value="ACA85905"/>
        <property type="gene ID" value="Swoo_1619"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1619"/>
    <dbReference type="eggNOG" id="COG1536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047835_2_0_6"/>
    <dbReference type="OMA" id="QVRPFEF"/>
    <dbReference type="OrthoDB" id="847822at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000090">
        <property type="entry name" value="Flg_Motor_Flig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023087">
        <property type="entry name" value="Flg_Motor_Flig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011002">
        <property type="entry name" value="FliG_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032779">
        <property type="entry name" value="FliG_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028263">
        <property type="entry name" value="FliG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30534">
        <property type="entry name" value="PTHR30534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01706">
        <property type="entry name" value="FliG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14841">
        <property type="entry name" value="FliG_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14842">
        <property type="entry name" value="FliG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003161">
        <property type="entry name" value="FliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00954">
        <property type="entry name" value="FLGMOTORFLIG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48029">
        <property type="entry name" value="SSF48029"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00207">
        <property type="entry name" value="fliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="12" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7 12" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="16" id="KW-0969">Cilium</keyword>
    <keyword evidence="8 12" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="16" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliG_N" evidence="15">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_M" evidence="14">
        <location>
            <begin position="132"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_C" evidence="13">
        <location>
            <begin position="233"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR003161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA85905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="349" mass="38015" checksum="2A0D251C2244EF95" modified="2008-04-29" version="1">MSNNTEVAEAGGKGSSVIDDLTGVEKTAILLLSLSEADAASILKHLEPKQVQKVGMVMAAMEDFGQEKVIAVHQLFLDEVQKYSSIGFNSEEFVRKALTAALGEDKAGNLIEQIIMGSGAKGLESLKWMDSRQVATIIQNEHPQIQTIVLSYLEPDQAAEIFAQSPENTRLDLMMRIANLEEVQPAALQELNDIMEKQFAGQGGAQAAKMGGLKAAANIMNYLDTGVESQLMETMRESDEEMAQQIQDLMFVFENLIDVDDLGIQALLREVQQDVLMKALKGADDQLKEKILGNMSKRAAELLADDLEAMGPIRISEVEVAQKEILSIARRLSDSGEIMLGGGGGEEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM96</accession>
    <name>B1KM96_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase</fullName>
            <shortName evidence="3">SHCHC synthase</shortName>
            <ecNumber evidence="3">4.2.99.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menH</name>
        <name evidence="5" type="ordered locus">Swoo_0208</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:25597"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="4.2.99.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 3/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AB hydrolase superfamily. MenH family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.20" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322858.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0208"/>
    <dbReference type="ESTHER" id="shewm-b1km96">
        <property type="family name" value="MenH_SHCHC"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84509">
        <property type="protein sequence ID" value="ACA84509"/>
        <property type="gene ID" value="Swoo_0208"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0208"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_38_2_6"/>
    <dbReference type="OMA" id="LNDWYQQ"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070205">
        <property type="term" value="F:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01660">
        <property type="entry name" value="MenH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022485">
        <property type="entry name" value="SHCHC_synthase_MenH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03695">
        <property type="entry name" value="menH_SHCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="13"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="259" mass="28884" checksum="221C73AE5C3910FD" modified="2008-04-29" version="1">MLALSSYGDKSKPALVMLHGFLGAQTDWQAIVKQLTNQFYCVCIDLPGHGLSPTLALPTPGFDLITKHIQAAIDSLSIEKYHLLGYSLGGRIALHLARNNTQKLLSLSLESCHPGLQTSEEKQLRAKNDLSWSKKLTELPIEAFLALWYQQGVFAELSIEARQKLIEKRRHNNPVGLLNIYLASSLAEQSNLWELPASLPFSCHYIVGSDDSKFLALATRWKEQTSVKVSVVKQAGHNVHLAAPQEYSNWLIQTLIEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB7</accession>
    <name>B1KMB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322879.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0229"/>
    <dbReference type="EnsemblBacteria" id="ACA84530">
        <property type="protein sequence ID" value="ACA84530"/>
        <property type="gene ID" value="Swoo_0229"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0229"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_3_6"/>
    <dbReference type="OMA" id="CGGDTMN"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="48720" checksum="4856A9D42D55CAAC" modified="2008-04-29" version="1">MTIKDETKKQILQLHQKVDFQYGRSTGFSDYHAYLYQNKQASHKQVDNLSEGDINNQVLYGMTIAVKDNIEVAGMPNTLGNKALAGHIPQHDACIITRLKEAGAVINGKANMHELALGVTNINPSYGHALNAYNPEYFAGGSSGGTAVAVALGLADAGIGTDTGGSSRIPAALNGIVGFRPTTGRYPNDGLGLISKTRDTAGPMAKDVDTLARLDAVLAGEPSIDSLPSFPPKKLRLGIPRAYFYGNTEPAVLAAVEDVLQALAKAGVTLIEVDPQGIEALNQSISFPVVLYEAKQHIQDYVEKALPGTAIEDFAAQICSGDVKNLVDSIFNQPIPEPMYQEAINSFRPKLQSLYQDYFDKHRLDAVIFPATPLTAQKITNDNDLVILNGSEEPTFSTYIRNADPASNAGIPGLVIPIGFNPEGLPISLEIDGPAGSDRQVITIGKLIETIIKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB9</accession>
    <name>B1KMB9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322881.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0231"/>
    <dbReference type="EnsemblBacteria" id="ACA84532">
        <property type="protein sequence ID" value="ACA84532"/>
        <property type="gene ID" value="Swoo_0231"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0231"/>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045390_0_0_6"/>
    <dbReference type="OMA" id="CQGCHND"/>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020015">
        <property type="entry name" value="Decahaem_cyt-c_DmsE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010177">
        <property type="entry name" value="Paired_CXXCH_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09699">
        <property type="entry name" value="Paired_CXXCH_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03508">
        <property type="entry name" value="decahem_SO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01905">
        <property type="entry name" value="paired_CXXCH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767202" evidence="1">
        <location>
            <begin position="26"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="2">
        <location>
            <begin position="84"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="2">
        <location>
            <begin position="147"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="2">
        <location>
            <begin position="191"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="2">
        <location>
            <begin position="238"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="316" mass="34442" checksum="1267E4E5E25534B8" modified="2008-04-29" version="1" precursor="true">MICRLVKRVLVGIAALAWVSVSVNAARWDHLTGEQLEQKLTEKFTQGQYSPKGADSCLMCHRKNEVVMAIFDGAHGSMNNKQSPMAGLQCEACHGPQGKHNKGGKEPMIAFGEESKLSASAQNSVCQGCHNDPKQMAWHTSTHNLEEIACADCHNVHSAKDPALDKLTINDTCTSCHSKEKADMNKRSSHPLKWDQMTCIDCHSPHGSMNESALNKPTINDTCYSCHAEKRGPVLWEHAPVTENCVTCHNPHGSVNDDLLNSRAPQLCQQCHAPDGHASRVVPEPGMDAFGGGKSCLNCHNKIHGSNHPSGSLFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC3</accession>
    <name>B1KMC3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytoplasmic chaperone TorD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322885.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0235"/>
    <dbReference type="EnsemblBacteria" id="ACA84536">
        <property type="protein sequence ID" value="ACA84536"/>
        <property type="gene ID" value="Swoo_0235"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0235"/>
    <dbReference type="eggNOG" id="COG3381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077650_7_1_6"/>
    <dbReference type="OMA" id="ISMLAQV"/>
    <dbReference type="OrthoDB" id="1995553at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="24884" checksum="95A2B07F55BFA160" modified="2008-04-29" version="1">MSLDNKFDFEAGQGLARILHHVLLSYPTVETLDNLKTHSVAQSWPEFGLSADNTAGRAALTTYLSQWSAEQLNELKLDYGQLFFGPGEPNAMPWGSVYLGEQQLLNDRSTLDLMAFYKQQGISFELEFTQPLDHIALFFAVIDSLLGQLVLNPDDEPVRRTLAVLMQQHMLPWSHRCFELAIEHAQTDFYRGIAHLALDFQQVLAVVFQVIPMPVRLHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KME0</accession>
    <name>B1KME0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S23 ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324284.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1652"/>
    <dbReference type="EnsemblBacteria" id="ACA85938">
        <property type="protein sequence ID" value="ACA85938"/>
        <property type="gene ID" value="Swoo_1652"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1652"/>
    <dbReference type="eggNOG" id="COG0399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129874_0_0_6"/>
    <dbReference type="OMA" id="QIRFLYY"/>
    <dbReference type="OrthoDB" id="2023580at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="125" mass="14424" checksum="9ADF442BE73C7395" modified="2008-04-29" version="1">MRFEQLDVWKRASRLSCEIYKATETVQNWGFKDQITRSGLSVPSNIAEGEERETNKEKVRFLYYAKGSLGELVTQLYIGIEIGYLEKHSSLEMVKEAKELAKVLGTMIKKKESKIKEEPAVYQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ7</accession>
    <name>B1KMJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324341.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1710"/>
    <dbReference type="EnsemblBacteria" id="ACA85995">
        <property type="protein sequence ID" value="ACA85995"/>
        <property type="gene ID" value="Swoo_1710"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1710"/>
    <dbReference type="eggNOG" id="ENOG5032S0P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100980_0_0_6"/>
    <dbReference type="OMA" id="YIGIKLK"/>
    <dbReference type="OrthoDB" id="1708262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021367">
        <property type="entry name" value="DUF2982"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11201">
        <property type="entry name" value="DUF2982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="25246" checksum="35AEEED4CFE1E447" modified="2008-04-29" version="1" precursor="true">MQSKLVEVRSSVKRNAITLTFVGLVGIILGLVLFLSSSVLFAPALCAFALGIIATVLGVSKQMEPEVSITLSPDGLSYHHRRGSLFIEWENVQRFDIPKSLDGLETIELPFIGIRLKKINPVLDVIPGRLATGLLTEQRPLLMSAVTLDENLEVLEDYLNSEFTPLLVNGERYRGVLAMYGHRSEMLNRNLGYHQYIPFDCLDREPREFLTLLRDYLQEVRESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN1</accession>
    <name>B1KMN1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3138"/>
    <dbReference type="EnsemblBacteria" id="ACA87409">
        <property type="protein sequence ID" value="ACA87409"/>
        <property type="gene ID" value="Swoo_3138"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3138"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_16_6"/>
    <dbReference type="OMA" id="LDRHEHG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="183"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="31665" checksum="DA93328FD3E4B6C6" modified="2008-04-29" version="1">MKTTESRVHTQKEVAEFTHVKELGGIELLSASYHKQNFSRHSHEGYTVGVIESGAQRFYRTGGNHIAPQNSIILVNADEVHNGCSAAENGWSYRAMYPLPEQFSQLNQELGLASKGAPYFPEPVVYDKPMAEMLRMMFHTLDTSDNRLLRETLLYSAMMKLISRHSRTKAEPSKPAAAQTQLLLVKEFLDDYPSIDISLEELATLAGLSPFYLIKQFQKKYGLPPHAYQIQSRIRLAKQKIKEGYKLMDVALECGFHDQSHLSRHFKRTMGVTPGKYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV6</accession>
    <name>B1KMV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325820.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3214"/>
    <dbReference type="EnsemblBacteria" id="ACA87484">
        <property type="protein sequence ID" value="ACA87484"/>
        <property type="gene ID" value="Swoo_3214"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3214"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_4_1_6"/>
    <dbReference type="OMA" id="DAPRCGI"/>
    <dbReference type="OrthoDB" id="1335734at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="135" mass="15003" checksum="6F878717868C915D" modified="2008-04-29" version="1">MKEIVRINHVGLRVKSLAISRAFYEKLGFEFIEGPIGPEPVAVMEHPCGININFILNGSEDEVLNVLMDVPNKHTGFTHIALEINDIKAVQEKLAELEFPVTEGPITVPSGAMFLFIRDPDDNVIEFHLPAKLAN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMW0</accession>
    <name>RS11_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsK</name>
        <name type="ordered locus">Swoo_4667</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327241.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMW0"/>
    <dbReference type="SMR" id="B1KMW0"/>
    <dbReference type="STRING" id="392500.Swoo_4667"/>
    <dbReference type="EnsemblBacteria" id="ACA88917">
        <property type="protein sequence ID" value="ACA88917"/>
        <property type="gene ID" value="Swoo_4667"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4667"/>
    <dbReference type="eggNOG" id="COG0100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072439_5_0_6"/>
    <dbReference type="OMA" id="KWGVAHI"/>
    <dbReference type="OrthoDB" id="1713391at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000141140" description="30S ribosomal protein S11">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <sequence length="130" mass="13924" checksum="A4D01DA02990C693" modified="2008-04-29" version="1">MAKSPSRSPRKRVRKQVADGMAHIHASFNNTIITITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGVAAQDYGVKNLEVFVKGPGPGRESAIRALNSVGYKITNITDVTPIPHNGCRPPKKRRV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX6</accession>
    <name>RL16_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplP</name>
        <name type="ordered locus">Swoo_4683</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327255.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMX6"/>
    <dbReference type="SMR" id="B1KMX6"/>
    <dbReference type="STRING" id="392500.Swoo_4683"/>
    <dbReference type="EnsemblBacteria" id="ACA88933">
        <property type="protein sequence ID" value="ACA88933"/>
        <property type="gene ID" value="Swoo_4683"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4683"/>
    <dbReference type="eggNOG" id="COG0197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078858_2_1_6"/>
    <dbReference type="OMA" id="KGAVEYW"/>
    <dbReference type="OrthoDB" id="1786618at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000143029" description="50S ribosomal protein L16">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <sequence length="136" mass="15425" checksum="BEC744AF6A8297C3" modified="2008-04-29" version="1">MLQPKRMKFRKMFKGRNRGLANGTEVSFGDFGLKAVGRGRLTARQIEAARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMDGVSEELAREAFALAAAKLPLKTTFVTKTVM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMY0</accession>
    <name>RL2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplB</name>
        <name type="ordered locus">Swoo_4687</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327257.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMY0"/>
    <dbReference type="SMR" id="B1KMY0"/>
    <dbReference type="STRING" id="392500.Swoo_4687"/>
    <dbReference type="EnsemblBacteria" id="ACA88937">
        <property type="protein sequence ID" value="ACA88937"/>
        <property type="gene ID" value="Swoo_4687"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4687"/>
    <dbReference type="eggNOG" id="COG0090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036235_2_1_6"/>
    <dbReference type="OMA" id="SCIELRP"/>
    <dbReference type="OrthoDB" id="961486at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000141615" description="50S ribosomal protein L2">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="275" mass="30093" checksum="7E35AE73E48DE7BA" modified="2008-04-29" version="1">MAIIKCKPTSAGRRHVVKVVNTDLHKGKPFAGLLAKKSKSGGRNNTGRITVRHVGGGHKQHYRIIDFKRIKDGIPAKVERLEYDPNRTANIALVLYADGERRYILAAKGMQAGDKIQSGIDAEIKVGNALPLRNIPVGSVVHAVEMKPGKGAQIARSAGTYVQVVARDGEYATLRLRSGEMRKVPVDCRATMGEVGNAEHMLRQLGKAGAKRWRGVRPTVRGVAMNPIDHPHGGGEGRTSGGRHPVSPWGVPTKGYKTRSNKRTDKYIVRRRNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN09</accession>
    <name>B1KN09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327284.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4716"/>
    <dbReference type="EnsemblBacteria" id="ACA88966">
        <property type="protein sequence ID" value="ACA88966"/>
        <property type="gene ID" value="Swoo_4716"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4716"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_23_0_6"/>
    <dbReference type="OMA" id="YFGPGED"/>
    <dbReference type="OrthoDB" id="1826274at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="16950" checksum="2FD292CB7F0305EB" modified="2008-04-29" version="1">MSDFVQVSLAHKSDLRAIDALEQSCFHGHSYPDFFFRQALDCWPNGFWVAKDNQGNIVGYLLASTSDKPNVCWLLSVAVADIARGKGVGSKLISQLINALASDINQINLTVAPDNPAKALYLRSGFTEQGFETDYFGEGEPRLLMSYFRAEHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN37</accession>
    <name>B1KN37_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327311.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4744"/>
    <dbReference type="EnsemblBacteria" id="ACA88994">
        <property type="protein sequence ID" value="ACA88994"/>
        <property type="gene ID" value="Swoo_4744"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4744"/>
    <dbReference type="eggNOG" id="ENOG5032V31">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1833851_0_0_6"/>
    <dbReference type="OMA" id="YIVGIIK"/>
    <dbReference type="OrthoDB" id="1914682at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="15706" checksum="7F70902CD4CE806E" modified="2008-04-29" version="1" precursor="true">MKTILNAICSKGLPSRDIRNANKVNILALLWAFSLMLTSYLSTQAWFTEIPIAIAFLLHTGIGITMVFSYRHFLIELDEMERKIQLDALALSVGVTIISFSSYSILDKNGILPELDSAYLIALMALTYMVGIISGRLRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN84</accession>
    <name>B1KN84_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0280"/>
    <dbReference type="EnsemblBacteria" id="ACA84581">
        <property type="protein sequence ID" value="ACA84581"/>
        <property type="gene ID" value="Swoo_0280"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0280"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_27_6"/>
    <dbReference type="OMA" id="ANDLLWW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032404">
        <property type="entry name" value="CpxA_peri"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038515">
        <property type="entry name" value="CpxA_peri_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16527">
        <property type="entry name" value="CpxA_peri"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="188"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="251"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="459" mass="51347" checksum="C80F9DBABDB00635" modified="2008-04-29" version="1">MASIISPDKIPNRIFIKLLLGFWLCSSIIIATVGLLPLLQQNHDRAPLPPHLEKLLSKFADRISNQPQLLEAGKLSRLTHRRNFKGKPVRLYLVNDQGRVINTDKVSRGMRRFMLMAEEANQPISHQFKNELLFGPYNFDVTGKQYSLYGRFADHHPRPWFFFLAENKLLTLSLAIALSGLLCGLLAWHLGKPLRTLRLSADSLAAGDLTNRVDDATTQRKDEIGLLAQAFNGMADSVENMVNSQQRLISDISHELRTPLTRLQLALALARKKGVDTAETQRIGYEAEQLELMIAELLELSRVKLNRHDIKHLVSLNETLNQVLDDADFEASQQGKRLVIDIDDAITLPTNPRPLARAIENLLRNAISYAEMEINIIAQAAGNQIIITISDDGPGIENKQDLHEIFKPFYRPQSARERESGGWGLGLAIAKAAIDAHQGEITAQNRASQGLEIIIKLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN85</accession>
    <name>B1KN85_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0281</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322931.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0281"/>
    <dbReference type="EnsemblBacteria" id="ACA84582">
        <property type="protein sequence ID" value="ACA84582"/>
        <property type="gene ID" value="Swoo_0281"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0281"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="LAEVWDW"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="25774" checksum="065E8A9F20A70B34" modified="2008-04-29" version="1">MNHILLIDDDLGLSELLGQLLELEGFKLTLANDGEAGLALALEQKFDLILLDVMLPKLNGFEVLKALRVKKQTPVLMLTARGDEIDRVVGLEIGADDYLPKPFNDRELIARIKAIIRRTNLQIDETQPSIHEYGDIKLDPSRQEVYCQDMLLILTGTEFTLLFEMLQNGGELISKELLSEKVLGKKLMPFDRSLDMHLSNLRKKLPDRTDGRPRVKTIRGKGYIWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNC1</accession>
    <name>B1KNC1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signaling modulator of AmpD, AmpE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0317"/>
    <dbReference type="EnsemblBacteria" id="ACA84618">
        <property type="protein sequence ID" value="ACA84618"/>
        <property type="gene ID" value="Swoo_0317"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0317"/>
    <dbReference type="eggNOG" id="COG3725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054212_2_2_6"/>
    <dbReference type="OMA" id="GPFRDAW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031347">
        <property type="entry name" value="AmpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17113">
        <property type="entry name" value="AmpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="284" mass="31635" checksum="B4D0ED5F6B460701" modified="2008-04-29" version="1">MMALFSLLVAILVERLKFLPQSWQLDSILNLYSKTLFGNKQLSSDVMMALALILPAIAVQVAMWAVNGIFWGLVSLTLWVAISILCFSHLKQRQLFKRYMQAACRGDSQACYHFADALDPNVSLDAVSEEELGAKVGQSAAWLNYRFYGAVALFLIILGPAGAVFYCTVRYFSDQNQEEKLELPLVEDVLMVLDWLPSRIFAFGYVLSGQFSQAFACWMQYALNIRSSAREVVTQVAQAAEPQPETSATPICTQSTLSLLQLSKRNFILLLVCLSMLTIFGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNC4</accession>
    <name>B1KNC4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="7">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0320</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="7">Binds 3 lipoyl cofactors covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Forms a 24-polypeptide structural core with octahedral symmetry.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322970.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0320"/>
    <dbReference type="EnsemblBacteria" id="ACA84621">
        <property type="protein sequence ID" value="ACA84621"/>
        <property type="gene ID" value="Swoo_0320"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0320"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_0_6"/>
    <dbReference type="OMA" id="TMEFESF"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006256">
        <property type="entry name" value="AcTrfase_Pyrv_DH_cplx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF2">
        <property type="entry name" value="PTHR43178:SF2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01348">
        <property type="entry name" value="PDHac_trf_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="95"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="194"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="314"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="617" mass="64490" checksum="D1C443C7A7C42752" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF7</accession>
    <name>GH109_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName>Glycosyl hydrolase family 109 protein</fullName>
            <ecNumber>3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1749</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Glycosidase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="1">Binds 1 NAD(+) per subunit. The NAD(+) cannot dissociate.</text>
    </comment>
    <comment type="PTM">
        <text>Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324380.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNF7"/>
    <dbReference type="SMR" id="B1KNF7"/>
    <dbReference type="STRING" id="392500.Swoo_1749"/>
    <dbReference type="CAZy" id="GH109">
        <property type="family name" value="Glycoside Hydrolase Family 109"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86034">
        <property type="protein sequence ID" value="ACA86034"/>
        <property type="gene ID" value="Swoo_1749"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1749"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046965_0_0_6"/>
    <dbReference type="OMA" id="MESGKHA"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0326">Glycosidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" description="Tat-type signal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5000317251" description="Glycosyl hydrolase family 109 protein">
        <location>
            <begin position="32"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="66"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="137"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="157"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="246"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="467" mass="52860" checksum="D07F6FC66EE7FADA" modified="2008-04-29" version="1" precursor="true">MKNFNRRAFLKAAGATTAGLVTSGLILPASAQPQKMPPKPSNGKSVMGLISPKLSTVRVGFIGVGQRGYGHVKHFCHLEGVEIKAICDTDPAVLDRAIDFVVEQGLAKPNAYTGSEHTYRDMLQRDDIDIAIISTPWQWHAPMAIDTMENDKHAFVEVPLAMSVEECWQIVDTAERTQKNCMMMENVNYGRDELMVLNMVRQGVFGELIHGEAAYIHELRWQMKELESKTGSWRTHWHTKRNGNLYPTHGLGPVSQYMNINRGDRFDYLTSMSSPALGRALYAKREFPADHERNQLNYINGDMSTSLIKTVKGRTIMVQHDTTTPRPYSRHNLIQGTNGVFAGFPNRIALEQSPFERDEKGGESFHRWDMDMTRWYDKYDHPLWQQMGKEAERNGGHGGMDFLMLWRMVYCLRNAEPLDQDVYDGAAWSVVNILSEESVNNRSNSVTFPDFTRGAWKTGKPLGIVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNM2</accession>
    <name>B1KNM2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipoprotein releasing system, transmembrane protein, LolC/E family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1815</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324445.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1815"/>
    <dbReference type="EnsemblBacteria" id="ACA86099">
        <property type="protein sequence ID" value="ACA86099"/>
        <property type="gene ID" value="Swoo_1815"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1815"/>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_1_6"/>
    <dbReference type="OMA" id="ERTQMIG"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011925">
        <property type="entry name" value="LolCE_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02212">
        <property type="entry name" value="lolCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="10">
        <location>
            <begin position="27"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="304"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="418" mass="45239" checksum="9F17EC34935E8F85" modified="2008-04-29" version="1" precursor="true">MNPFLSIWVGWRFYMARQSNSLISFISFASTAGIALGVAVLIVVLSAMNGFESELENRMLGVVSHGELSGVNQPVNNWPAIVEDAKKVPGIVASAPFIRLQGLVQKPGGFQGLTILGVDTQYEQKVSNIAQFMPAETWEKLAETDKNNIVLGRGLAKSLGLNLGDSLSMYMPNVNADPTVKRIGSAKSYRFTVAGIFELGGELDLSTAYVPMQYAASILAMGEQVSGIRIKADKVFEAPRLIRELGFSQDQYLYITDWTRTQGHLYQDIQLVRSVMYLVLALVIAVACFNIVSTLVMAVRDKQSEIAILLTMGMKRSAIMTIFIVQGALNGVLGCLLGGLFGVLIAENLSWIAKAIEGALGVKLLSADIYFIDFLPSELHLVDVGVVLLLALVMSLIATLYPAWKASQTPPASALAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNR5</accession>
    <name>B1KNR5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325859.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3253"/>
    <dbReference type="EnsemblBacteria" id="ACA87523">
        <property type="protein sequence ID" value="ACA87523"/>
        <property type="gene ID" value="Swoo_3253"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3253"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_635871_0_0_6"/>
    <dbReference type="OMA" id="GRQHPPE"/>
    <dbReference type="OrthoDB" id="397741at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766903" evidence="1">
        <location>
            <begin position="23"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="149"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="393" mass="45042" checksum="524F977492F27716" modified="2008-04-29" version="1" precursor="true">MLFPYKLVTAVFYTGLSLLFFTACQSVSTSNENNCHFANVKFETDFSTGRLDRCQQLSDTRFLLTLRPENRPINDSAWYAFKLVTQSPQEVEIVMEVEGGKHRYLPKVSRDGEIWSLKEYKLRSQQLKMHFAATDQPIWVAGQEIIDNQDYLEWGEALMAQGKANHEQLGLSTEQRPIMKLEASTDKEGKEWLLVLGRQHPPELTGAMALFPFSEVLLSNTQLAKEFRERFNIVIIPNLNPDGVEVGNWRHNANGVDLNRDWGKFKQAETRVVASYLERLIASGDKIHFAVDFHSTRKDIFYTMPSDYGLQNPQMVEHWLDELDNQYTGFKVIQQPGNNPDIGVFKQYIADKYGVHAITYEMGDNTNRRFIDNLAINAANSLMQTMLASKPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS8</accession>
    <name>B1KNS8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase III subunit alpha</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3266</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325872.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3266"/>
    <dbReference type="EnsemblBacteria" id="ACA87536">
        <property type="protein sequence ID" value="ACA87536"/>
        <property type="gene ID" value="Swoo_3266"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3266"/>
    <dbReference type="eggNOG" id="COG0587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001600_0_0_6"/>
    <dbReference type="OMA" id="NECRRMG"/>
    <dbReference type="OrthoDB" id="561611at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041931">
        <property type="entry name" value="DNA_pol3_alpha_thumb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="9">
        <location>
            <begin position="7"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1157" mass="129641" checksum="C95B8487FED11142" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU8</accession>
    <name>B1KNU8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Formyltetrahydrofolate deformylase</fullName>
            <ecNumber evidence="3">3.5.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Formyl-FH(4) hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purU</name>
        <name evidence="5" type="ordered locus">Swoo_3286</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19833"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="EC" id="3.5.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PurU family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.10" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325892.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3286"/>
    <dbReference type="EnsemblBacteria" id="ACA87556">
        <property type="protein sequence ID" value="ACA87556"/>
        <property type="gene ID" value="Swoo_3286"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3286"/>
    <dbReference type="eggNOG" id="COG0788">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038395_3_2_6"/>
    <dbReference type="OMA" id="RFMQVLP"/>
    <dbReference type="OrthoDB" id="979667at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008864">
        <property type="term" value="F:formyltetrahydrofolate deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016742">
        <property type="term" value="F:hydroxymethyl-, formyl- and related transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04875">
        <property type="entry name" value="ACT_F4HF-DF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08648">
        <property type="entry name" value="FMT_core_Formyl-FH4-Hydrolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01927">
        <property type="entry name" value="PurU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041729">
        <property type="entry name" value="Formyl-FH4-Hydrolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004810">
        <property type="entry name" value="PurU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044074">
        <property type="entry name" value="PurU_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42706">
        <property type="entry name" value="PTHR42706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01575">
        <property type="entry name" value="FFH4HYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00655">
        <property type="entry name" value="PurU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="4">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="277" mass="31271" checksum="C6945BEAE7A526B8" modified="2008-04-29" version="1">MERKVLITECADAQGLITKITGVCFSHQLNIIKNSEFVDNVQGRFFMRAELEGEFNDSLILADLEEVLPDSSSIKLVNTDKKRIVILVTKEAHCLGDILMKAYYGGLDVEIAAIVGNYQNLQPLADKFDIPFHFVSHEGCTRVEHEKKIVEVINEYEPDYLVLAKFMRILTPEFVEQFPNRIINIHHSFLPAFIGASPYRQAWERGVKIIGATAHFVNNCLDEGPIIKQDVIPVDHSYSAEDLAKNGRDVEKSVLSKALQLVVHEEVIVYGNKTVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY8</accession>
    <name>B1KNY8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin synthase sulfurylase MoeB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327336.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4770"/>
    <dbReference type="EnsemblBacteria" id="ACA89019">
        <property type="protein sequence ID" value="ACA89019"/>
        <property type="gene ID" value="Swoo_4770"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4770"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_10_3_6"/>
    <dbReference type="OMA" id="MIYDALE"/>
    <dbReference type="OrthoDB" id="1408716at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012730">
        <property type="entry name" value="Mopterin_Synthase_Sase_MoeB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02355">
        <property type="entry name" value="moeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="19"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="27919" checksum="7EF092404A433570" modified="2008-04-29" version="1">MSSTTDIDEILSDSEILRYSRHISIKAMDFEGQEKLKLAKVLVIGAGGLGCASTQYLAVAGIGSMTLVDFDTVELSNLQRQVLHQDKNIGQPKVESAKETLSELNPHLQIETINAVLDDHEFDALITQHTLVMDCTDNVAVREQLNKSCFAHKVPLISAAAIRMEGTVTVFDYQGETPCYHCFSKLFGEQHLTCVESGILAPVVGMIGCLQAVEAIKVISGIGKPLIGRILMIDAMTMEFREMKLSKQASCKVCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP22</accession>
    <name>B1KP22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327370.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4804"/>
    <dbReference type="EnsemblBacteria" id="ACA89053">
        <property type="protein sequence ID" value="ACA89053"/>
        <property type="gene ID" value="Swoo_4804"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4804"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="FMHARRR"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="32360" checksum="BC7DB5547EF9B686" modified="2008-04-29" version="1">MGAFERAQLFKLIVELGSMVATAKALNISPSAVSKRLAELESQLGVQLLKRSTRSIVITEAGEHFYQEVRELSGRWQSLVDETATLGESPSGRLTVAAPAPVLSRVLMPMLPGFNANFPEIKLELLSVDYDDLPLRSADISLARHIEAFDSGTFVGVPLCEYRNGLFASPEYINKHGSPHKVEELVQHSCLCYGKENRSYLWCLGEESVEVKGRLVSDNTEVIIQAAVQGMGIAYIPRMIIERELACGELMSVLTYVESQRFSMWGYYQQLAYLPAKTRAFIDYFRHSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP48</accession>
    <name>B1KP48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327396.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89079">
        <property type="protein sequence ID" value="ACA89079"/>
        <property type="gene ID" value="Swoo_4830"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4830"/>
    <dbReference type="eggNOG" id="COG3332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047037_1_1_6"/>
    <dbReference type="OMA" id="TFTERNM"/>
    <dbReference type="OrthoDB" id="1721287at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="PTHR17985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="28863" checksum="E88B0C01B041502D" modified="2008-04-29" version="1">MCILFIALEQHPKYPLIVCANRDEFHHRPTQQAHFWMPENELLAGKDLQSGGSWLGVNRLGDFAALTNFRDPQAQQDGMRSRGELVINALKHHEPMTTAWLREHSQNYNPFNLVFGNRKELYCYNSSQKALTRLTSGFHSISNGALDDVWPKMARGTIALETSITQPDEPDIQALLAIMKDETRAEESELPQTGIAIEWERLLSSIYIRHPEYGTRSTSIILQDTSGNTRFIEVRYDGKGRNLGQQEFYLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE9</accession>
    <name>B1KPE9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0421</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0421"/>
    <dbReference type="EnsemblBacteria" id="ACA84719">
        <property type="protein sequence ID" value="ACA84719"/>
        <property type="gene ID" value="Swoo_0421"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0421"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047522_1_2_6"/>
    <dbReference type="OMA" id="SRACRQW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="235"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="350" mass="39597" checksum="E0A633A0A9A2A006" modified="2008-04-29" version="1">MNETYLIRSAALQGFSDLVKSYDGEPAELLEAVGLSFEELNSKETLISFLAVQQLLELSANKLNVPGFGLALSQGQNIDMLGQLGLLMASCKTLKDVMLSVQRYMSLHSPAENWVFSEVNNLVYITRFEYEANTVPLKQIKELSLGVCFKFLQLFIGLSFTATRVELSHSPVSELKAYRKIFKVDVQFNQEYDQIIFDKKYLQQVVHLDDQNRNEFLEKYIDNAVSATDYNNLERQIMGLLIQYIGSENASLDNISRKLGMNKRTLQRQLKTQQINFKGILANIRGRKACWYLSASEMSITLISEALGYKDVSAFSRAFKLLYGTSPSQWRKARGEFDCEGDCVATGVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPG7</accession>
    <name>B1KPG7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Succinate dehydrogenase iron-sulfur subunit</fullName>
            <ecNumber evidence="7">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1836</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="7">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="7">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324466.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1836"/>
    <dbReference type="EnsemblBacteria" id="ACA86120">
        <property type="protein sequence ID" value="ACA86120"/>
        <property type="gene ID" value="Swoo_1836"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1836"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_0_2_6"/>
    <dbReference type="OMA" id="DGQYFGP"/>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6 7" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="235" mass="26581" checksum="D60A5FD761D618E8" modified="2008-04-29" version="1">MNLNIAIYRYNPDVDAKPYMKDYTLEVAEGTDMMVLDALMLLKEQDPTLAFRRSCREGVCGSDGLNMNGKNGLACITPVSTFKGKKIEIRPLPGMPVVRDLIVDLSQFYKQYEKIKPYLINDEKTPAREHLQSPEERAHLDGLYECIMCACCSTACPSFWWNPDKFIGPSGLLHAYRFLIDSRDTATEERLSELDDAYSVFRCHSIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPL3</accession>
    <name>B1KPL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324512.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1882"/>
    <dbReference type="EnsemblBacteria" id="ACA86166">
        <property type="protein sequence ID" value="ACA86166"/>
        <property type="gene ID" value="Swoo_1882"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1882"/>
    <dbReference type="eggNOG" id="ENOG5031FQU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1863797_0_0_6"/>
    <dbReference type="OMA" id="MIALNMS"/>
    <dbReference type="OrthoDB" id="1674434at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15532" checksum="DC616DB7E912C892" modified="2008-04-29" version="1">MLTDKETALLNAATDLIKEHGMIALNMSDVHKKAGYSRAAQYQSFSDKNSLLAALCMRELVQNTSAVNEQRYTEMTSDFTVVLRPVVYNYLKLSDRLMIDSAFNHMLDAVQSLPDVEQFSFLKQGFNFLNQERINAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPR4</accession>
    <name>B1KPR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SNARE associated Golgi protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325933.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3328"/>
    <dbReference type="EnsemblBacteria" id="ACA87597">
        <property type="protein sequence ID" value="ACA87597"/>
        <property type="gene ID" value="Swoo_3328"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3328"/>
    <dbReference type="eggNOG" id="COG1238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125997_1_0_6"/>
    <dbReference type="OMA" id="WSLLFAW"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="15556" checksum="6584474AC129AB90" modified="2008-04-29" version="1" precursor="true">MTTLWLMFSAAFLAATLLPGGSEVLLVALLNESRSEWLSLVVVATIGNTLGAMTSFYLGRLGRFARSPEAMTQGKYRHSVNMIQKYGYWALLLSWAPLIGDLLCLLAGWMKLPLLRSTLMILIGKCIRYLLVAAFALQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ58</accession>
    <name>B1KQ58_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327487.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4922"/>
    <dbReference type="EnsemblBacteria" id="ACA89171">
        <property type="protein sequence ID" value="ACA89171"/>
        <property type="gene ID" value="Swoo_4922"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4922"/>
    <dbReference type="eggNOG" id="COG3059">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102847_1_0_6"/>
    <dbReference type="OMA" id="WIGVFKF"/>
    <dbReference type="OrthoDB" id="1744031at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016865">
        <property type="entry name" value="RclC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007339">
        <property type="entry name" value="RclC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40106">
        <property type="entry name" value="PTHR40106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04224">
        <property type="entry name" value="DUF417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028065">
        <property type="entry name" value="UCP028065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="15528" checksum="FCC0E5D92FCB8B47" modified="2008-04-29" version="1">MKTTNFGYLFGVLGVSLVLLWLGVYKFTATEAKLIEPLIVNHPLLSWVYQVLSVQTVSNLIGSVEILVGIGLLLGFKNAKVGLVSGLSAVGIFVVTLSFMLTTPDTWKVSDGVLITNFFLLKDWVFLAIAIMVVETHRGALKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ92</accession>
    <name>B1KQ92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent hydrolase of the beta-lactamase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323096.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0449"/>
    <dbReference type="EnsemblBacteria" id="ACA84747">
        <property type="protein sequence ID" value="ACA84747"/>
        <property type="gene ID" value="Swoo_0449"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0449"/>
    <dbReference type="eggNOG" id="COG2220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020884_0_2_6"/>
    <dbReference type="OMA" id="HQPPISL"/>
    <dbReference type="OrthoDB" id="767622at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="115"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="42413" checksum="8987E6E36E2B1935" modified="2008-04-29" version="1" precursor="true">MKPLIAITLTLIFGGAMLTMTTSSIEPSINNAKGTHHSDKGGYINTAADFTEETAILPLLMRYATEKRVDAEPEQMQPIIELTSKQLMELPSDQDMVIRLGHSSIFMQLDGKKWLIDPVFSERASPFSFIGPKRFHPTPISLKDLPEIDGVLISHDHYDHLDKATIKHLASTSTQFIVPLGVDKHLLRWGVAANKVQSLDWWESFNLGSTKITAMPTQHFSGRGIFDKNETLWASYVIESQQNKIYFSGDSGYFAGFKEIGDRFGPFTLTMVETGAYDADWPTIHMTPEQSLQAHIDLRGETMMPIHNGTFDLAFHSWYEPLERIVKLANDTDVKLATPMMGQGLTLKNNQLNTSQLSTTEYWWRTETQREMALAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ93</accession>
    <name>B1KQ93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323097.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84748">
        <property type="protein sequence ID" value="ACA84748"/>
        <property type="gene ID" value="Swoo_0450"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0450"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_6"/>
    <dbReference type="OMA" id="KSFAFWP"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="22598" checksum="03B5849597125ACA" modified="2008-04-29" version="1">MDKKISRSELKRRAIIGAAMSEFQTKGFKATSMDDVAKRAEVSKRTVYNHFSSKEALFSAIILEMMALLCAFEYFTFSDDIALEVQLEKLVDIEVEQLKSQAFMDMARVIIAEAVHSPELIQGAMDEFNKQETPLNTWFQAALEAGALKGQSHEIIVTQFVGVIKAFCFWPQLLQGAAFPSDEEVVAIKKTVVEMVLKQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQK6</accession>
    <name>B1KQK6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_1961</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324591.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1961"/>
    <dbReference type="EnsemblBacteria" id="ACA86245">
        <property type="protein sequence ID" value="ACA86245"/>
        <property type="gene ID" value="Swoo_1961"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1961"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_127_0_6"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007891">
        <property type="entry name" value="CHASE3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05227">
        <property type="entry name" value="CHASE3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="11">
        <location>
            <begin position="505"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="12">
        <location>
            <begin position="582"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="11">
        <location>
            <begin position="633"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="12">
        <location>
            <begin position="710"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="1027"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="1324"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="1447"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="1593"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="927"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1373"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1496"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA86245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1713" mass="191518" checksum="F4C01447002046FD" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ7</accession>
    <name>B1KQZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326087.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87753">
        <property type="protein sequence ID" value="ACA87753"/>
        <property type="gene ID" value="Swoo_3487"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3487"/>
    <dbReference type="eggNOG" id="ENOG5033H87">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1446731_0_0_6"/>
    <dbReference type="OrthoDB" id="1959488at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036782">
        <property type="entry name" value="NE0471-like_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143880">
        <property type="entry name" value="SSF143880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="21546" checksum="172D924B4DCCBA43" modified="2008-04-29" version="1">MNTIFDVIPNEDWELAIGFSNGEYRLLNLSIPKKEYGWEELANPLLMKRYTFNRTAIDWEFGGTLDAEYLYRNSVSVNMPDLARHSVRVCYKNQAPTTKDKRHHVYCVYLYPFSEKVFAVGESIGGGHGDRGGFSSFTLNELLTWEEWKLHFELSGCSWAIEMVEMSENIDQLVRLLVSEACKRNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR53</accession>
    <name>B1KR53_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PhoD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323218.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0574"/>
    <dbReference type="EnsemblBacteria" id="ACA84870">
        <property type="protein sequence ID" value="ACA84870"/>
        <property type="gene ID" value="Swoo_0574"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0574"/>
    <dbReference type="eggNOG" id="COG3540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020671_1_0_6"/>
    <dbReference type="OMA" id="AMYLLVW"/>
    <dbReference type="OrthoDB" id="165142at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD" evidence="1">
        <location>
            <begin position="309"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="649" mass="73573" checksum="10472289386B777D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR81</accession>
    <name>B1KR81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flp/Fap pilin component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323246.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0602"/>
    <dbReference type="EnsemblBacteria" id="ACA84898">
        <property type="protein sequence ID" value="ACA84898"/>
        <property type="gene ID" value="Swoo_0602"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0602"/>
    <dbReference type="eggNOG" id="COG3847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171854_2_0_6"/>
    <dbReference type="OMA" id="INTAFTK"/>
    <dbReference type="OrthoDB" id="2065691at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007047">
        <property type="entry name" value="Flp_Fap"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04964">
        <property type="entry name" value="Flp_Fap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="69" mass="7334" checksum="28FE903D0FD31035" modified="2008-04-29" version="1">MNKFYCNTMAFLATYKKDERGVTAIEYGLIGVAMAVALTAAFASDGNLMTALNTAFTKITDSLTKITAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR96</accession>
    <name>B1KR96_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">4-hydroxyphenylacetate 3-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2019"/>
    <dbReference type="EnsemblBacteria" id="ACA86303">
        <property type="protein sequence ID" value="ACA86303"/>
        <property type="gene ID" value="Swoo_2019"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2019"/>
    <dbReference type="eggNOG" id="COG2368">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023920_1_0_6"/>
    <dbReference type="OMA" id="NPQVNRA"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004925">
        <property type="entry name" value="HpaB/PvcC/4-BUDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024719">
        <property type="entry name" value="HpaB/PvcC/4-BUDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024674">
        <property type="entry name" value="HpaB/PvcC/4-BUDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36117">
        <property type="entry name" value="PTHR36117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03241">
        <property type="entry name" value="HpaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11794">
        <property type="entry name" value="HpaB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000331">
        <property type="entry name" value="HpaA_HpaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpaB_N" evidence="3">
        <location>
            <begin position="33"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="HpaB" evidence="2">
        <location>
            <begin position="314"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="175"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="181"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="474"/>
            <end position="477"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000331-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="504" mass="57492" checksum="C92EEDA6CCD96332" modified="2008-04-29" version="1">MNKTIPKLEAMDDFCTLDYKLQLCRSAAKGAWTGARYIESLKDGRQVWYDGEVIDVTRHPSFQGLLMALAELYDKQRLENNSADMLTELDDGSLQVSASYIVPSTREELDKKWRNSHKWMQLSYGQLPRVPDFMANVVVGLYDFRHELGKVDPQFEKNAEDYYHYCREHDICLTHALGDPQIDRSASPVENPDHALRVVKRTKEGIVVHGAKQLATLAPYCHEALIYLSPAFYMRESPEFVAWFSVPMNAPGLKFLCRESHVGTSNGFRHAFSQSYDEQDSMLFFDHVFIPMNRVFLLENTEVAAKGFHELNKWSLYVGQIRFYHRLRTFLGVTSLVAKSIGVDGFREIMNRVGELTSYVELVRSCLVGIDSETRISSAGNIAPGSTLALDSFASQIAPRINEILRDIGGSGIIMQPSAKDLANPELRPYLEKYMKGKGVDVDFKTDLFRLAFELIGDRFGARQELYEIWNRGDIVRTRMALCKSYPDLNNCEEEIKDLIKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRE8</accession>
    <name>B1KRE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324700.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86355">
        <property type="protein sequence ID" value="ACA86355"/>
        <property type="gene ID" value="Swoo_2071"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2071"/>
    <dbReference type="HOGENOM" id="CLU_1495227_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764786" evidence="1">
        <location>
            <begin position="23"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="180" mass="19981" checksum="F2D4F1F8B0626810" modified="2008-04-29" version="1" precursor="true">MKKTITHLLSLSLMITFLTACGAAHVRTEKSSSDLHQYKNIYLGKVDIHSQEEAAKTNEELQLKMVEWEGFARTELKNYVEKSEYTLVDTLDNKDTTLAVDLDIDLVYGNRAARYFGGFGAGKGSVDSVLKVTDPKTQEVKFHAVAESDLSVGAFGGSMESVLKTNIQKLIEQYPRAAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK8</accession>
    <name>B1KRK8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326106.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3509"/>
    <dbReference type="EnsemblBacteria" id="ACA87773">
        <property type="protein sequence ID" value="ACA87773"/>
        <property type="gene ID" value="Swoo_3509"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3509"/>
    <dbReference type="eggNOG" id="COG0824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101141_7_1_6"/>
    <dbReference type="OMA" id="DMLCHDG"/>
    <dbReference type="OrthoDB" id="1786865at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002864">
        <property type="entry name" value="Acyl-ACP_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008272">
        <property type="entry name" value="HB-CoA_thioesterase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006684">
        <property type="entry name" value="YbgC/YbaW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01643">
        <property type="entry name" value="Acyl-ACP_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003230">
        <property type="entry name" value="YbgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01328">
        <property type="entry name" value="4HBCOA_THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="146" mass="16995" checksum="F041E5D39AE2381A" modified="2008-04-29" version="1">MQNKKALNYSQTFHFPIQIYYEDTDFSGVVYHPNFLKYFERAREHVIGADILASLWQEQGLGFAVYRSDMLCHDGVEFADIIEVKTQFCFESKYRTIWKQEIWRPNASKPAVTANIEMVCMNKARQLAPMTPELLALLKQSFDSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ8</accession>
    <name>B1KCZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322676.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0026"/>
    <dbReference type="EnsemblBacteria" id="ACA84327">
        <property type="protein sequence ID" value="ACA84327"/>
        <property type="gene ID" value="Swoo_0026"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0026"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_6_4_6"/>
    <dbReference type="OMA" id="CILANEE"/>
    <dbReference type="OrthoDB" id="1772343at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="101" mass="11438" checksum="E3D32F57AAB8D746" modified="2008-04-29" version="1">MQKEIDVDAMVSNAENAAKWLKAIANPYRLMILCLLLENEYSVTELNETVPLSQSALSQHLAVLRAQDLVSTRKSSQVVFYKLKNEQVTEVISILHKQYCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD06</accession>
    <name>B1KD06_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322702.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0052"/>
    <dbReference type="EnsemblBacteria" id="ACA84353">
        <property type="protein sequence ID" value="ACA84353"/>
        <property type="gene ID" value="Swoo_0052"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0052"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018914_1_0_6"/>
    <dbReference type="OMA" id="GRMWWAV"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767252" evidence="1">
        <location>
            <begin position="22"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="591" mass="67258" checksum="73B99B11EF11012C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD24</accession>
    <name>B1KD24_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-lactamase</fullName>
            <ecNumber evidence="6">3.5.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a beta-lactam + H2O = a substituted beta-amino acid</text>
            <dbReference type="Rhea" id="RHEA:20401"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35627"/>
            <dbReference type="ChEBI" id="CHEBI:140347"/>
            <dbReference type="EC" id="3.5.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.6" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326192.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="SMR" id="B1KD24"/>
    <dbReference type="STRING" id="392500.Swoo_3595"/>
    <dbReference type="EnsemblBacteria" id="ACA87859">
        <property type="protein sequence ID" value="ACA87859"/>
        <property type="gene ID" value="Swoo_3595"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3595"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068048_0_0_6"/>
    <dbReference type="OMA" id="THWHADR"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017001">
        <property type="term" value="P:antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001018">
        <property type="entry name" value="Beta-lactamase_class-B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00744">
        <property type="entry name" value="BETA_LACTAMASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767254" evidence="4">
        <location>
            <begin position="37"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="5">
        <location>
            <begin position="80"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="272" mass="30519" checksum="2CC41287BCDD6235" modified="2008-04-29" version="1" precursor="true">MSKQIDLFITKFKVIRLFTHLLPCLFLLGVSSITAAAPSSSQVNWSSELIKITQVYPTLYLVKSYKTIKLYQDKPAQTFDSNSFIYVDNSDAYLIDTPWSESDMPDLMRWLEVKKLQLKGTIVTHYHQDRAGGLGYLDRLGSATYASKMTNKLLVNDKQPTSNHSFSGDKFALLKGKIEAFYPGSGHSMDNLVIWLPEEKVIVGGCLLKDNKVNNLGWTGDADLANWYHSISKVKAEFPKVEFIFPGHGEGAKGQSILDHSLSVTKEVARFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD26</accession>
    <name>B1KD26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3597</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3597"/>
    <dbReference type="EnsemblBacteria" id="ACA87861">
        <property type="protein sequence ID" value="ACA87861"/>
        <property type="gene ID" value="Swoo_3597"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3597"/>
    <dbReference type="eggNOG" id="ENOG5032UPM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162092_1_0_6"/>
    <dbReference type="OMA" id="CVGCPKK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9544" checksum="EBE8BDD5375EE160" modified="2008-04-29" version="1">MLQIIEQVKDQLPLYESDTFICGPDNNCQGCPKKLLELVDTELTYWESAIERGVTPNFDEITRFGKLCKNVRRGLVRNNLIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD50</accession>
    <name>B1KD50_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tripartite ATP-independent periplasmic transporter DctQ component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3621</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326218.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3621"/>
    <dbReference type="EnsemblBacteria" id="ACA87885">
        <property type="protein sequence ID" value="ACA87885"/>
        <property type="gene ID" value="Swoo_3621"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3621"/>
    <dbReference type="eggNOG" id="COG4665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_2_2_6"/>
    <dbReference type="OMA" id="ICMAGNT"/>
    <dbReference type="OrthoDB" id="2073326at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="173" mass="19421" checksum="C2F7F9322D4363E0" modified="2008-04-29" version="1">MNRVEKLTEFIGKGVSWFTLFIVLMTLAVVVLRYAFSTGATAIQEGALYLHGAVLTLAAGYTLKHDGHVRVDIFYRHFSSRGQHWVDLLGTLFLLFPVCIFITYSCFDYVLASWRYAETSVEAGGLEYVYLQKSLLLLLVVSLLLQGCVELVRHASALFANKREESEETGEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD80</accession>
    <name>B1KD80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326248.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87915">
        <property type="protein sequence ID" value="ACA87915"/>
        <property type="gene ID" value="Swoo_3653"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3653"/>
    <dbReference type="eggNOG" id="ENOG5032XV0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_733401_0_0_6"/>
    <dbReference type="OrthoDB" id="1857505at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="361" mass="40580" checksum="47600F427EB855ED" modified="2008-04-29" version="1" precursor="true">MKRILASVLVCLAAHIVQVDAKDRLEGFVLRGDHSGTVGERNHFDNPNGSTWARHVDGIVVQAEWAHLQPNKDGAIRANNVIDQAISAVTTWNNANPSNKLGIKLRVFAGIYSPGWVGDETGEFFAQYKNGKEGYMPFFWKAKKFRPLWSNFQTKLAAKYDSHPLLREVAVSGCMTHNAETMWRNPRDNSRDDGKKNIDIMRDNGLTLLKDENCLKWQIRVAASKWPKTHIGMAYNMWQDYENGNAKKPEFVNTLMDYCIERAPGRCILGNNSLGVSDIGDENKTTDVTYYLRQKGDAGNLIYVQTETVATDIHLAIDHGADRLHAAMAELPKLKALNKVSATYLQSDDMQDARLNLKTNN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA1</accession>
    <name>KDSA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-dehydro-3-deoxyphosphooctonate aldolase</fullName>
            <ecNumber evidence="1">2.5.1.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">3-deoxy-D-manno-octulosonic acid 8-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">KDO-8-phosphate synthase</fullName>
            <shortName evidence="1">KDO 8-P synthase</shortName>
            <shortName evidence="1">KDOPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phospho-2-dehydro-3-deoxyoctonate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kdsA</name>
        <name type="ordered locus">Swoo_3674</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="EC" id="2.5.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KdsA family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.55" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326269.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDA1"/>
    <dbReference type="SMR" id="B1KDA1"/>
    <dbReference type="STRING" id="392500.Swoo_3674"/>
    <dbReference type="EnsemblBacteria" id="ACA87936">
        <property type="protein sequence ID" value="ACA87936"/>
        <property type="gene ID" value="Swoo_3674"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3674"/>
    <dbReference type="eggNOG" id="COG2877">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036666_0_0_6"/>
    <dbReference type="OMA" id="FRGIPTM"/>
    <dbReference type="OrthoDB" id="687380at2"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00357">
        <property type="reaction ID" value="UER00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008676">
        <property type="term" value="F:3-deoxy-8-phosphooctulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019294">
        <property type="term" value="P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00056">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006269">
        <property type="entry name" value="KDO8P_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21057">
        <property type="entry name" value="PTHR21057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01362">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000091837" description="2-dehydro-3-deoxyphosphooctonate aldolase">
        <location>
            <begin position="1"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00056"/>
        </source>
    </evidence>
    <sequence length="282" mass="30729" checksum="E86510BE683BFC88" modified="2008-04-29" version="1">MSNKTIGLGSIEIANDKPFVLFGGMNVLESRDLAMKIAETYAETTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLKIFEEIKSTFNLPLITDVHEIHQCAPVAEVVDIIQLPAFLARQTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGNDEIILCERGSSFGYNNLVVDMLGMDEMKQTGYPVIFDATHALQRPGGRADSAGGRRAQATELARSGMALGLAGLFIEAHPDPDNAKCDGPCALPLHQLEAYLTQMKAVDDLVKSFDAIDTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG7</accession>
    <name>B1KDG7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0672</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323315.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0672"/>
    <dbReference type="EnsemblBacteria" id="ACA84968">
        <property type="protein sequence ID" value="ACA84968"/>
        <property type="gene ID" value="Swoo_0672"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0672"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008878_3_0_6"/>
    <dbReference type="OMA" id="QTQGYVR"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="3">
        <location>
            <begin position="32"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="4">
        <location>
            <begin position="381"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="507"/>
            <end position="508"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="532" mass="57432" checksum="896C21B4E97E56CF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG8</accession>
    <name>B1KDG8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323316.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84969">
        <property type="protein sequence ID" value="ACA84969"/>
        <property type="gene ID" value="Swoo_0673"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0673"/>
    <dbReference type="HOGENOM" id="CLU_1453484_0_0_6"/>
    <dbReference type="OMA" id="PAVHENK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="21010" checksum="D8688E1DC5D87C4F" modified="2008-04-29" version="1">MRLRIVTTTLFLLFCIGCTEKGELSLETEIELVDMTLLELVGKSIPAVHENKLEGFPYPTLVIELDKSEHPSSSPFDRVRVQTLVKEQKMYSILADKFNLNRDECLSVYRSHSKALEEQYSFILQKRQIEVSGEIIEIDDGYLSPDNKIKVDISCTMADSANSETFTLRLDNTSLSALAKGRLSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL9</accession>
    <name>B1KDL9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA chaperone ProQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">proQ</name>
        <name evidence="6" type="ordered locus">Swoo_2132</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ProQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2132"/>
    <dbReference type="EnsemblBacteria" id="ACA86416">
        <property type="protein sequence ID" value="ACA86416"/>
        <property type="gene ID" value="Swoo_2132"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2132"/>
    <dbReference type="eggNOG" id="COG3109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113254_0_0_6"/>
    <dbReference type="OMA" id="WRYLKGV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033592">
        <property type="term" value="F:RNA strand annealing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034057">
        <property type="term" value="F:RNA strand-exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00749">
        <property type="entry name" value="ProQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023529">
        <property type="entry name" value="ProQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016103">
        <property type="entry name" value="ProQ/FinO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036442">
        <property type="entry name" value="ProQ/FinO_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035236">
        <property type="entry name" value="ProQ_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38106">
        <property type="entry name" value="PTHR38106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04352">
        <property type="entry name" value="ProQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17516">
        <property type="entry name" value="ProQ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00945">
        <property type="entry name" value="ProQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48657">
        <property type="entry name" value="SSF48657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="ProQ" evidence="5">
        <location>
            <begin position="9"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="23655" checksum="621DB0637907E26C" modified="2008-04-29" version="1">MEVMMESTEKLTDTNAILAYLYETFPLCFIAEGETKPLKIGLFQDLAERLADDSKVSKTQLRIALRRYTSSWRYLKGVKAGAQRIDLDGQACGELEQEHIEHAQLTLKESQEKAKAKRIAKATAAKASEKASKKPAKKVAPKRTKPAPKPVKEAAPAVNLTPAVLNELKQNQRVNVKLGKSPVAGVIVDIKKEDVQVQLDSGLTVKVRVEHIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX8</accession>
    <name>B1KDX8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">clpB</name>
        <name evidence="13" type="ordered locus">Swoo_3720</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326312.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3720"/>
    <dbReference type="EnsemblBacteria" id="ACA87980">
        <property type="protein sequence ID" value="ACA87980"/>
        <property type="gene ID" value="Swoo_3720"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3720"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_0_6"/>
    <dbReference type="OMA" id="SKMMQGE"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="412"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="857" mass="95719" checksum="C23DA1D4F3D6E29B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDY7</accession>
    <name>B1KDY7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326321.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3729"/>
    <dbReference type="EnsemblBacteria" id="ACA87989">
        <property type="protein sequence ID" value="ACA87989"/>
        <property type="gene ID" value="Swoo_3729"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3729"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074744_1_0_6"/>
    <dbReference type="OMA" id="QFDIETH"/>
    <dbReference type="OrthoDB" id="731668at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766979" description="DUF4097 domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4097" evidence="3">
        <location>
            <begin position="38"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="315" mass="33820" checksum="9285527E93632DB5" modified="2008-04-29" version="1" precursor="true">MMIKHLSRCLLLPLVLVSQFALASESIDKQVKVDEGLNLNIKVLRGDVTIQSWDKQEVSIQGTLDELSEGFIVEHQGNELTLEDKMPRQFNGKNKEGSLLTFKVPRSLNLTVSGLSADYKVTQVQGGISINSISGSVHLDSLDKQVYIKTVSGDINATALKGEISLQTVSGDIIDKQSKGEVSYKLVSGELTADSLAKDVTIEQVSGDTNIKLASLNSLAVRTISGEVELTAESISDKATLSSVSGDLELTLNGGTDARFKINGGPGGRINNQLTSDKPSKEKYSPTSYLKFSLGDAHANIDISTISGEITLKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE24</accession>
    <name>B1KE24_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SH3 type 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0715</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0715"/>
    <dbReference type="EnsemblBacteria" id="ACA85010">
        <property type="protein sequence ID" value="ACA85010"/>
        <property type="gene ID" value="Swoo_0715"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0715"/>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094106_0_2_6"/>
    <dbReference type="OMA" id="HKGREGW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016476">
        <property type="entry name" value="SH3_dom_pro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006158">
        <property type="entry name" value="UCP006158_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04211">
        <property type="entry name" value="SH3_and_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764740" evidence="8">
        <location>
            <begin position="20"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="9">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="103"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="21428" checksum="CD49E7040062C145" modified="2008-04-29" version="1" precursor="true">MLRILALVGLMLLSPSLLAAGQTRYISDEVYLFLHGGPGTQFRILGSVEAGQEITVLGEKQGNYSKIIDHKGREGWVETKMISAQKSLRVQLPEVQAELTKTKAELEQVVNSSDSNVQELRQVKAQLARAEESLEQASTERDRATRELANIQKNERFQMWQEGGIIAAAGLLMGIILVYLPRPRRKKRSNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE54</accession>
    <name>B1KE54_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323387.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0745"/>
    <dbReference type="EnsemblBacteria" id="ACA85040">
        <property type="protein sequence ID" value="ACA85040"/>
        <property type="gene ID" value="Swoo_0745"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0745"/>
    <dbReference type="eggNOG" id="COG1430">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097039_4_0_6"/>
    <dbReference type="OMA" id="YLANTPW"/>
    <dbReference type="OrthoDB" id="1934378at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12812" checksum="47FE3226860FEE61" modified="2008-04-29" version="1" precursor="true">MKKTQLSTPKGSRIEHIYLANTPWLRLRGLLGRKQLTTEQGMLISPCNSVHTMGMRYPLDIVYLNSKNKVLKITSNLAPWRSSACRGATQVLELSAGNSENKNIKQGDTIVWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE3</accession>
    <name>B1KEE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutathione-dependent formaldehyde-activating, GFA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324864.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2240"/>
    <dbReference type="EnsemblBacteria" id="ACA86521">
        <property type="protein sequence ID" value="ACA86521"/>
        <property type="gene ID" value="Swoo_2240"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2240"/>
    <dbReference type="eggNOG" id="COG3791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_5_0_6"/>
    <dbReference type="OMA" id="ACDCDFC"/>
    <dbReference type="OrthoDB" id="1474484at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15695" checksum="3D545B97D6F6680C" modified="2008-04-29" version="1">MFTSHGACSCAGVKVRIRLPDPIEQYSPRACDCDFCIARGIAYLSDPRGSLDIDCIEPIEIQRQGSNQADFLTCATCHTVIAVSVKLEGKLIGALNSSLLSHHQQLQSATQVSPKLLMPKDKLERWQSVWLKMTINDSSNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEJ8</accession>
    <name>B1KEJ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324918.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2297"/>
    <dbReference type="EnsemblBacteria" id="ACA86576">
        <property type="protein sequence ID" value="ACA86576"/>
        <property type="gene ID" value="Swoo_2297"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2297"/>
    <dbReference type="eggNOG" id="COG3139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150108_0_1_6"/>
    <dbReference type="OMA" id="HMTIGTD"/>
    <dbReference type="OrthoDB" id="2038051at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009749">
        <property type="entry name" value="DUF1315"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07023">
        <property type="entry name" value="DUF1315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="94" mass="11023" checksum="D77E65CDE2B68D26" modified="2008-04-29" version="1">MSDEINKVIDEMPQEVYERLRTGVELGKWEDGTRLSDAQRESTMQLVMLYQARRLNQTDHFTISREGTINELSKAELKKQFKGESIAEFKEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU3</accession>
    <name>B1KEU3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326438.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3850"/>
    <dbReference type="EnsemblBacteria" id="ACA88108">
        <property type="protein sequence ID" value="ACA88108"/>
        <property type="gene ID" value="Swoo_3850"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3850"/>
    <dbReference type="eggNOG" id="ENOG5032NNQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_581238_0_0_6"/>
    <dbReference type="OMA" id="YKQAEIM"/>
    <dbReference type="OrthoDB" id="1806853at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764356" evidence="2">
        <location>
            <begin position="19"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="470" mass="51757" checksum="61C4BB75B902AA95" modified="2008-04-29" version="1" precursor="true">MKYHMLALAIVFSFNSYADQAVPVANAAEAEVVLPSQSADNVQQAQSDPADLTENAINDYMSDVQARVAKAGKSHSIQFFSGQASLNINRNDPDWAIFREQAIQEAVIKARESYLTTLNRDVVQEQFREFFSSKGKPEPTASDFQSEAGVTSLLDKAILLAETMLDKELVEQGIEPATFKKATPQIKRDLFRDAIGTKTLSKAYGDLSGMTVQQVYEFIREDGTGHIGVVMALSAKKREHIRALVESDGRVEPIPARANPEFANVSAGLAAIPEIYLEFGTKVFYDDKGYPMLVSFGQSGVRYTRDPDERDLEREDAHQFAIDNAYGALAATYNMNGDHVRESIQKSSKTKSETFDLIKDGSVRKNSGAVRKAIMRESEALSSMTASIQGLTGVSVHHKWRKKHPITGKEMSGVVVVWHPVTVQNAELMQSGKSAAEIEAIMAPNEPNSPQNGGKVQGRKSVDRFDPEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX1</accession>
    <name>B1KEX1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutamate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0827</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323469.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0827"/>
    <dbReference type="EnsemblBacteria" id="ACA85122">
        <property type="protein sequence ID" value="ACA85122"/>
        <property type="gene ID" value="Swoo_0827"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0827"/>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028929_0_1_6"/>
    <dbReference type="OMA" id="EIDCEDF"/>
    <dbReference type="OrthoDB" id="1478871at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="592" mass="67052" checksum="F17FC9B8902A997F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEZ4</accession>
    <name>B1KEZ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323492.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85145">
        <property type="protein sequence ID" value="ACA85145"/>
        <property type="gene ID" value="Swoo_0850"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0850"/>
    <dbReference type="HOGENOM" id="CLU_1282488_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="215" mass="24210" checksum="A2CA578433F9EE63" modified="2008-04-29" version="1">MSRFTSIILQQKGITLQQFFDRFNVSFQEELLELIDTIKHVNLRPVEALCIYSAGGFRSIGYAVREEGDVAATESFDLNFLAALKGHDDLEAMFSNSVSSESDLSFQICADEWLHINKIDCFSKTNAIVESNLDQLYDAGYEQKVIQTEILNTIITSLAELTSQGMASPPEFSSDSFFSVQFSGGANSNILFESSKQLNSSHWHKKVERFVKENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF15</accession>
    <name>B1KF15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323513.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0872"/>
    <dbReference type="EnsemblBacteria" id="ACA85166">
        <property type="protein sequence ID" value="ACA85166"/>
        <property type="gene ID" value="Swoo_0872"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0872"/>
    <dbReference type="eggNOG" id="ENOG502ZANK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090906_0_0_6"/>
    <dbReference type="OMA" id="SYPMIAI"/>
    <dbReference type="OrthoDB" id="1979400at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016870">
        <property type="entry name" value="UCP028137"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028137">
        <property type="entry name" value="UCP028137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="231" mass="25428" checksum="789E66093FAA7E6E" modified="2008-04-29" version="1">MSSTSTHKPRPMVDLLVSIVIPAFILMKLSGDDQLGASGGLMLALSFPLGWGIFELIKYRKFNFIALLGLANVMLTGGIGLLELDLKWLAIKEAAIPAAIGIAVLISTFTSKPLIKALVFNPAVMDVDKIMKRLQQNNCMAAFEQRLMTATYLVAGSFAFSATMNYVLAKWLVTSPTGTPEFNAELGELTLYSYLMIALPSMVMMMGIFYYLWRTIRDLTGLKLEEVLANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF57</accession>
    <name>B1KF57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324940.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2319"/>
    <dbReference type="EnsemblBacteria" id="ACA86598">
        <property type="protein sequence ID" value="ACA86598"/>
        <property type="gene ID" value="Swoo_2319"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2319"/>
    <dbReference type="eggNOG" id="ENOG502Z7HQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048734_0_0_6"/>
    <dbReference type="OMA" id="QRHIYAK"/>
    <dbReference type="OrthoDB" id="451285at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010752">
        <property type="entry name" value="DUF1329"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07044">
        <property type="entry name" value="DUF1329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764368" evidence="1">
        <location>
            <begin position="21"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="451" mass="50862" checksum="6A19636CD91FE561" modified="2008-04-29" version="1" precursor="true">MKYLTLIPALLTLVSLNVTAKVTPEEASKIGKELTPLGAEMAANEAGTIPAWTGGLNSQNMPKSPDFGRPVNPFADEKPLFTITAKNMADYQDNLTQGQIAMFKKYPDYRMPVYKTHRTVAYPDSIYPLIEQNAQSASLIESGYGLVDFDTTIPFPIPNNGLEVVWNHITRFRGGSAVRVATAIPVQSGGAFVPVKITDRLVWPEYLEGGRDADKDKNVLFYYLQRITAPARLTGTALLIHETIDQFEEARRAWVYNSGQRRVRRAPNVAYDGPGAGTDGLRTTDNYDMYNGSPDRYEWTLKGKKEIYIPYNAYPLLNTELEYDELIGAGHLNPDYLRYELHRVWVVEANIKSGSRHIYSKRTLYIDEDSWGASVIDHFDNRGELWKVSEAHNIQFYDVDTPWMVAETLHDLDSGRYLVTGLSNEEPSFIKWGGKATRKDFTSAALRRVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF70</accession>
    <name>B1KF70_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2332</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324953.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2332"/>
    <dbReference type="EnsemblBacteria" id="ACA86611">
        <property type="protein sequence ID" value="ACA86611"/>
        <property type="gene ID" value="Swoo_2332"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2332"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_409875_0_0_6"/>
    <dbReference type="OMA" id="EPNMPYL"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="273"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="547"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="670" mass="75888" checksum="B2E240390E6A8122" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF86</accession>
    <name>B1KF86_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324969.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2348"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86627">
        <property type="protein sequence ID" value="ACA86627"/>
        <property type="gene ID" value="Swoo_2348"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2348"/>
    <dbReference type="eggNOG" id="COG3469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902827_0_0_6"/>
    <dbReference type="OrthoDB" id="2080107at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="1">
        <location>
            <begin position="10"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="308" mass="32821" checksum="922C0B1EE15184A3" modified="2008-04-29" version="1">MSQIKQWPRTAMVGYIDTTAIGSMSAITKEQIQSYNVIIFGFTDANGELPPQLQRAVKEVRQLEAPDTLNLISVGGAGGTLSLTSQTITNLLSGLKSEQLDGIDLDLEDPSIDIDTLSSFTAELSLQLADNYLLTIAPILAGTPDQPTLNIPGGASLKPLYSQIHFDAILVQAYNSGTYFSYPLPSDKNVLVSESSANIISAAYNSLQKDGEILSTSKIVIGIPSNAGAAPTQSNLWDTVNFEAIPVEVLSNVKSIQLGEYGIDSTQFGGLMSWSLNCDAQPSSYPPYFEAQNAPAGYFAAKVASKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC1</accession>
    <name>B1KFC1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325004.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86662">
        <property type="protein sequence ID" value="ACA86662"/>
        <property type="gene ID" value="Swoo_2383"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2383"/>
    <dbReference type="eggNOG" id="ENOG50301GD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1601580_0_0_6"/>
    <dbReference type="OMA" id="WRMVRKE"/>
    <dbReference type="OrthoDB" id="1732526at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="167" mass="19662" checksum="FCB2F6477EB5A356" modified="2008-04-29" version="1">MDHKQAWIYQGDAPKAGRKLLLLEPNELTIALPLIFRLVHPEEVMKKTEWFLSSIAEDDANRNLKYIALIPLLQKVTQLRKNSEPLLASLKELNNNLNEYFSDHGWRMVRKELSQIKKRQKKSHIELSKDIIAKLKIYMEDEKFESFDQAIDNLIAEAKFKNTEREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFG0</accession>
    <name>B1KFG0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidyl-peptidase</fullName>
            <ecNumber evidence="2">3.4.14.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S46 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326465.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3877"/>
    <dbReference type="MEROPS" id="S46.003"/>
    <dbReference type="EnsemblBacteria" id="ACA88135">
        <property type="protein sequence ID" value="ACA88135"/>
        <property type="gene ID" value="Swoo_3877"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3877"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013776_0_0_6"/>
    <dbReference type="OMA" id="PGRTNRW"/>
    <dbReference type="OrthoDB" id="99817at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070009">
        <property type="term" value="F:serine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019500">
        <property type="entry name" value="Pep_S46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38469">
        <property type="entry name" value="PTHR38469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10459">
        <property type="entry name" value="Peptidase_S46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023154128" description="Dipeptidyl-peptidase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="718" mass="80763" checksum="C6E0CFABC8293683" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFH3</accession>
    <name>B1KFH3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Folate-binding protein YgfZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326478.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3890"/>
    <dbReference type="EnsemblBacteria" id="ACA88148">
        <property type="protein sequence ID" value="ACA88148"/>
        <property type="gene ID" value="Swoo_3890"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3890"/>
    <dbReference type="eggNOG" id="COG0354">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_6_1_6"/>
    <dbReference type="OMA" id="VNFKKGC"/>
    <dbReference type="OrthoDB" id="1984573at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GcvT_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="PTHR22602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GCV_T" evidence="1">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="320" mass="34879" checksum="C4999A6DBB5D2ECD" modified="2008-04-29" version="1">MTQSVSQLAWNPSESAQLIFANLSHMGLMSVTGEQGRSFIHGQVTTDISSLESNQWRWGAHCDPKGKMLASFRTFSVADALFMMMPKDTLAADLPQLAKYAVFSKADLVDVSADWTILGVAGEQAQEWVNNYFGEITQELTEIPGGVLLKDGERFIIIIENAPSEPLLSSINTPIQESSAWQALEIQAGLPNLGVSHQGQFVPQMCNVQAINGISFKKGCYMGQETIARMKYRGGNKRALYILSGTSSQTLALDSRLELAIEDGFKKVGTIIELVQSGDQVLLSAVLPNDTENSAKLRVADDETSSLTIQPLPYSLEDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFH4</accession>
    <name>B1KFH4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tricorn protease homolog</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3891</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Degrades oligopeptides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S41B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326479.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3891"/>
    <dbReference type="EnsemblBacteria" id="ACA88149">
        <property type="protein sequence ID" value="ACA88149"/>
        <property type="gene ID" value="Swoo_3891"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3891"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4946">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005503_0_0_6"/>
    <dbReference type="OMA" id="WLRWPIS"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028204">
        <property type="entry name" value="Tricorn_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029414">
        <property type="entry name" value="Tricorn_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012393">
        <property type="entry name" value="Tricorn_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43253">
        <property type="entry name" value="PTHR43253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14684">
        <property type="entry name" value="Tricorn_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14685">
        <property type="entry name" value="Tricorn_PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036421">
        <property type="entry name" value="Tricorn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764381" description="Tricorn protease homolog" evidence="9">
        <location>
            <begin position="20"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="10">
        <location>
            <begin position="843"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="742"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="965"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036421-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1079" mass="120392" checksum="499B21384038DEF7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL1</accession>
    <name>B1KFL1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326516.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3928"/>
    <dbReference type="EnsemblBacteria" id="ACA88186">
        <property type="protein sequence ID" value="ACA88186"/>
        <property type="gene ID" value="Swoo_3928"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3928"/>
    <dbReference type="eggNOG" id="COG1765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022530_0_0_6"/>
    <dbReference type="OMA" id="FRRMFGN"/>
    <dbReference type="OrthoDB" id="1068793at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041080">
        <property type="entry name" value="YcaO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019938">
        <property type="entry name" value="YcaO_dom_prot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18381">
        <property type="entry name" value="YcaO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00702">
        <property type="entry name" value="TIGR00702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03549">
        <property type="entry name" value="TIGR03549"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="206"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="728" mass="81731" checksum="0A404EE14116A700" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM9</accession>
    <name>B1KFM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323542.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85195">
        <property type="protein sequence ID" value="ACA85195"/>
        <property type="gene ID" value="Swoo_0901"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0901"/>
    <dbReference type="eggNOG" id="ENOG5033M9Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1554229_0_0_6"/>
    <dbReference type="OMA" id="CIRACIF"/>
    <dbReference type="OrthoDB" id="2089742at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="172" mass="20245" checksum="FBA0C3A2C4054FDC" modified="2008-04-29" version="1">MNHNTMTLIGIQQIILDECLRALFYTRKYQTLDKTDFNKTCNACFTKTLIIQWCQIFGSRKEQVHWSKLQLPTGYPKFGQEIILSSNGLSAAEWKSYHNKMTTIRNKFFAHFDLDQLRGNIPCFEPALSVLLAYRQYLIDIIEHSNKQGQMVNRNFFDNDVLIEKIKEELAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFP2</accession>
    <name>B1KFP2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323555.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0915"/>
    <dbReference type="EnsemblBacteria" id="ACA85208">
        <property type="protein sequence ID" value="ACA85208"/>
        <property type="gene ID" value="Swoo_0915"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0915"/>
    <dbReference type="eggNOG" id="COG3930">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026435_0_0_6"/>
    <dbReference type="OMA" id="ALIHHEL"/>
    <dbReference type="OrthoDB" id="504489at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012656">
        <property type="entry name" value="CHP02421_QEGLA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012548">
        <property type="entry name" value="DUF1704"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007709">
        <property type="entry name" value="N-FG_amidohydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31817">
        <property type="entry name" value="PTHR31817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08014">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05013">
        <property type="entry name" value="FGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01154">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02421">
        <property type="entry name" value="QEGLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="664" mass="75682" checksum="C9E02E2921BFB646" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFZ2</accession>
    <name>B1KFZ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325041.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2421"/>
    <dbReference type="EnsemblBacteria" id="ACA86699">
        <property type="protein sequence ID" value="ACA86699"/>
        <property type="gene ID" value="Swoo_2421"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2421"/>
    <dbReference type="eggNOG" id="COG3198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100979_2_0_6"/>
    <dbReference type="OMA" id="HLWPWII"/>
    <dbReference type="OrthoDB" id="1707012at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008620">
        <property type="entry name" value="FixH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05751">
        <property type="entry name" value="FixH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="159" mass="18681" checksum="526CB6DA9F2A7FE1" modified="2008-04-29" version="1">MKQPQAWYKQFWPWFLIILPLCAVVASINLLFIAIDNKDALVSEDYYKDGKRINMDLKKIKYAKQLGMQFELQVDDNELTIIQHGGEEYLAALKVEFYHPTIESRDFKLVVTASGDKAYRVSLDKPITGAWEVRLEGYDQSWRIQKRLQIADDTEYWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG42</accession>
    <name>B1KG42_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325091.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2472"/>
    <dbReference type="EnsemblBacteria" id="ACA86749">
        <property type="protein sequence ID" value="ACA86749"/>
        <property type="gene ID" value="Swoo_2472"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2472"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_35_1_6"/>
    <dbReference type="OMA" id="PKRTTWL"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="300" mass="34019" checksum="D6F31B00ED5A60B1" modified="2008-04-29" version="1">MLSEQSLQLIDMVARVGSFTAAANKLHKVPSAVSYAVKQVEDELGSTLFERHHRSVSLTPAGEYFVKQARVILTNMESMKDDTKRVANGWQPTLSIALDNIVRADKISVLIADFYRHFTNVELIIRIEVFNGVWESIANGRSDIAIGATTAIPVGGDYHFRDMGEIEWAFLISKRHPLAEIDRPLTDDELRQYPSICLEDTSREIPKRMTWLLENQRRLVVPDWIRAINCFREGLGIGYMPMHFAEPFIRSGALLSKELERPKAPSPCCLAWNGANMSPAMAWVLDYLGDSEKLHNDWFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC2</accession>
    <name>B1KGC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326588.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4003"/>
    <dbReference type="EnsemblBacteria" id="ACA88259">
        <property type="protein sequence ID" value="ACA88259"/>
        <property type="gene ID" value="Swoo_4003"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4003"/>
    <dbReference type="eggNOG" id="COG3721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106714_0_0_6"/>
    <dbReference type="OMA" id="HSFGSIF"/>
    <dbReference type="OrthoDB" id="1938973at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd16829">
        <property type="entry name" value="ChuX_HutX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010413">
        <property type="entry name" value="HutX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06228">
        <property type="entry name" value="ChuX_HutX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030840">
        <property type="entry name" value="DUF1008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04108">
        <property type="entry name" value="HutX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="168" mass="18524" checksum="147A5725A0984690" modified="2008-04-29" version="1">MQPSNDVIREYFDSHPNAMPSQAAAELGTSELVVVSALPEEQVCLFPLVDKDELLSCLPHWGPMTTIVSVSGSIFEFKGDFPQGKYAYGYYNLITQGNGLHGHLSLDGLTAIALVSRPFRGKESHSINFFGSEGEMIFKVYLGRDSNRVLLPEQVTRFNALKERAIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGI0</accession>
    <name>B1KGI0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxythreonine-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.262</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(phosphohydroxy)-L-threonine dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pdxA</name>
        <name evidence="5" type="ordered locus">Swoo_1015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32275"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="EC" id="1.1.1.262"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">The active site is located at the dimer interface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PdxA family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.262" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323655.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1015"/>
    <dbReference type="EnsemblBacteria" id="ACA85308">
        <property type="protein sequence ID" value="ACA85308"/>
        <property type="gene ID" value="Swoo_1015"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1015"/>
    <dbReference type="eggNOG" id="COG1995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040168_2_0_6"/>
    <dbReference type="OMA" id="TAQVVMM"/>
    <dbReference type="OrthoDB" id="1414545at2"/>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00536">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037510">
        <property type="entry name" value="PdxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="328" mass="34990" checksum="44D9ECAD0BECB586" modified="2008-04-29" version="1">MTTKRIAITPGEPAGIGPDLVIQLAQQAWPAELVVCADPELLASRAKMLGLPLQLKPYQPSLEPKAQEAGTLTLAPFSLKTEAQCGKLDEQNSAYVVQTLGYAGEKNMNGEFDAVVTGPVHKGIINQSGIPFSGHTEFFANQANCQDVVMMLAAPGLQVALVTTHIPLAYVSKAITRDRLHQIIKILHTDLVTKFAIKQPKIYVCGLNPHAGEDGHLGREEIDTIIPALEELRAEGISLVGPLPADTIFQSKYLNDADVILAMYHDQGLPVLKSQGFGSSVNITLGLPYIRTSVDHGTALELAGTGKADIGSFVCALNKAIDLAAKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK6</accession>
    <name>B1KGK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323680.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1041"/>
    <dbReference type="EnsemblBacteria" id="ACA85334">
        <property type="protein sequence ID" value="ACA85334"/>
        <property type="gene ID" value="Swoo_1041"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1041"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_1_2_6"/>
    <dbReference type="OMA" id="LEDWHEN"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="218"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="298" mass="34094" checksum="7EB6A0AA7CD84A5F" modified="2008-04-29" version="1">MNNGADFMSSYQHILGVFSPYLSSQHALIKALILADKSKSKLTLIQLTTPKFNFMKSTNNSTDMQPLAENEDLIFQYQNLGLEIEIKEVKSNSVSTEVLAEVEQAQYDLVIVNYKHHHPIFHEFFFAEEWSLLRQKQISVMLVGDKQWQHEGNILTAIETDDTSEQHINFNKKLLDDSEEIASLLDNNIHLINCFHNNNLSMEVSISNSTVNHRDTKAQHWLDLIDSAQDYDLEDEQLHLIEGLPDHIIPTIAEQYHVNMVIVGASEHQGWLSQLKGHTSEQIIDQLHCDILAIKPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT7</accession>
    <name>B1KGT7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein, VC_A0107 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325147.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2529"/>
    <dbReference type="EnsemblBacteria" id="ACA86806">
        <property type="protein sequence ID" value="ACA86806"/>
        <property type="gene ID" value="Swoo_2529"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2529"/>
    <dbReference type="eggNOG" id="COG3516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111033_1_0_6"/>
    <dbReference type="OMA" id="RINIRYV"/>
    <dbReference type="OrthoDB" id="1278805at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008312">
        <property type="entry name" value="T6SS_TssB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35850">
        <property type="entry name" value="PTHR35850"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05591">
        <property type="entry name" value="T6SS_VipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028301">
        <property type="entry name" value="UCP028301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03358">
        <property type="entry name" value="VI_chp_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="18020" checksum="368225808BED30E5" modified="2008-04-29" version="1">MAKDGTVAPKERINIKYVPSTGDQQAEMELPLKMLIVGDFKGHAEDTQLEERQSVSVNKTNFESIMKESGLSVNTTVANKLTDNESDELNVELNFSSMKDFSPDAIATQVPEINKLIELREALVALKGPLGNIPSFRTKLQELIETEDSREQLLAELQTLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH81</accession>
    <name>B1KH81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323735.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1096"/>
    <dbReference type="EnsemblBacteria" id="ACA85389">
        <property type="protein sequence ID" value="ACA85389"/>
        <property type="gene ID" value="Swoo_1096"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1096"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011781_2_1_6"/>
    <dbReference type="OMA" id="YRPGKWG"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="3">
        <location>
            <begin position="8"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="2">
        <location>
            <begin position="310"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24_C" evidence="4">
        <location>
            <begin position="536"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="595" mass="65575" checksum="BBD561CE009F8DDD" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH95</accession>
    <name>B1KH95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323749.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85403">
        <property type="protein sequence ID" value="ACA85403"/>
        <property type="gene ID" value="Swoo_1110"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1110"/>
    <dbReference type="eggNOG" id="ENOG5031GDV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2920221_0_0_6"/>
    <dbReference type="OMA" id="WRHLQHQ"/>
    <dbReference type="OrthoDB" id="2065822at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="60" mass="7107" checksum="C178482CA1E71440" modified="2008-04-29" version="1">MFVSNAERWAKLCHQQAELIESLSESFPERRDNHINLGLSWRQLEERVSKGRSPRLNDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH96</accession>
    <name>B1KH96_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323750.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1111"/>
    <dbReference type="EnsemblBacteria" id="ACA85404">
        <property type="protein sequence ID" value="ACA85404"/>
        <property type="gene ID" value="Swoo_1111"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1111"/>
    <dbReference type="eggNOG" id="ENOG502Z9NJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074587_1_0_6"/>
    <dbReference type="OMA" id="VTNDYRF"/>
    <dbReference type="OrthoDB" id="1970612at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010239">
        <property type="entry name" value="CHP02001"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09694">
        <property type="entry name" value="Gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02001">
        <property type="entry name" value="gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764878" evidence="1">
        <location>
            <begin position="30"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="240" mass="26770" checksum="01DAF8E216EE34DF" modified="2008-04-29" version="1" precursor="true">MYKKFNKKRIAQVTGLVLATALISPIASAEVSGEVSLTNDYRFRGVSQTASNFAIQAGVDWSHDSGFFLGAWASNVDFDEPDYNGPDIELDIYAGYYGELNDDLSYDVTLYRYNYPGDSDLDYLEASIGVDFSGFRLAYWYTNDYGGSDLDLHYTEVNYSYEFYENWSLDLHYGYNFGDGIDDGEGFDSYADYSIGVSTEVAGIGLSLAWLDTDISDDNQVTDDLYNTEGTVLASVSYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHC9</accession>
    <name>B1KHC9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323783.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1144"/>
    <dbReference type="EnsemblBacteria" id="ACA85437">
        <property type="protein sequence ID" value="ACA85437"/>
        <property type="gene ID" value="Swoo_1144"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1144"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="YTEAYGQ"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764881" evidence="5">
        <location>
            <begin position="30"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="61"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="450"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="998" mass="108003" checksum="1B0255884CBFEC63" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHI2</accession>
    <name>B1KHI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UBA/THIF-type NAD/FAD binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325207.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2590"/>
    <dbReference type="EnsemblBacteria" id="ACA86867">
        <property type="protein sequence ID" value="ACA86867"/>
        <property type="gene ID" value="Swoo_2590"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2590"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_10_3_6"/>
    <dbReference type="OMA" id="SAKWKLE"/>
    <dbReference type="OrthoDB" id="1408716at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="11"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="264" mass="29058" checksum="419C330D90CB585C" modified="2008-04-29" version="1">MPLCDSDFMRYSRQVLLPEVGEHGQLALKSAKVLLVGVGGLGQLAAQYLAACGVGKLILADDDRVEVSNLPRQLLFDDDDIGEYKSKCASLKLMQRKPTCEVQSITQRLSTKNINRYIEGVNLVLDCSDNLPTRHTVNQACIETHTPLVTASVSHFSGFLFAVDMQRASEAGCYHCLFPHDTQVTQNCSTAGVLGPMVGTLASMQSLMAMNILLGVGKPFGKLLRFDGLKFSWYEAQLSQDPACPVCRNHIQTRQYNARCLEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP3</accession>
    <name>B1KHP3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2651"/>
    <dbReference type="EnsemblBacteria" id="ACA86928">
        <property type="protein sequence ID" value="ACA86928"/>
        <property type="gene ID" value="Swoo_2651"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2651"/>
    <dbReference type="eggNOG" id="COG5628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112329_1_1_6"/>
    <dbReference type="OMA" id="HYVEDVY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17508" checksum="2F73F6E710060562" modified="2008-04-29" version="1">MMNIVKVDDSNAHVYANLYQGYGAEFSRIIDDKPNENGLFEIYPQLTGSVTGYLLYIDGTPAALTAIDEKSPKAYEICDFYVLPCFRKNKVGKRFISSLFERLGGSWEIKQVAGAEHAISFWRDVVGDYTSGHYVEDVYEDHKWGTVTRQCFSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHP8</accession>
    <name>B1KHP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325273.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86933">
        <property type="protein sequence ID" value="ACA86933"/>
        <property type="gene ID" value="Swoo_2657"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2657"/>
    <dbReference type="HOGENOM" id="CLU_711506_0_0_6"/>
    <dbReference type="OMA" id="QSIWISI"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="42736" checksum="DE448318B77222A6" modified="2008-04-29" version="1" precursor="true">MKYALFLALISLGINQTLVVAAIPTLMTWSEQTPNSPSLGVLVLAVNLNLVSYWFGASRWGSVAKKLGVTRTLHIAALGFISANLLFVATFYSESPHIWQIGVCRILVGAFSCAFLPMAQMLLAANNDATSAALSRLSSALTLGRLIGPSLLFLPVSFEYLLLLPVVMILPVLFSRFDIEFVQTPLGTEQELVTIRDRQYFIYASAIMTTAIVAVFQFYALEFLNLKGYRGEQGSDMYASLMLATSVLLILYQVRVIPLLSQRRPELFLPILLFALMCGSTTLLVFGEFWWGLGLSLLGLIFAISGLPAWYTARLLASEENTVKQAKLSGYLTRAHTTGHIIGTGGASLFLHQQWTLTFLIAAFSIALLFCASRLHLLTNEPEQIKTY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI74</accession>
    <name>HCP_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydroxylamine reductase</fullName>
            <ecNumber evidence="1">1.7.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Hybrid-cluster protein</fullName>
            <shortName evidence="1">HCP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Prismane protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hcp</name>
        <name type="ordered locus">Swoo_1260</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>A + H2O + NH4(+) = AH2 + H(+) + hydroxylamine</text>
            <dbReference type="Rhea" id="RHEA:22052"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15429"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="1.7.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="1">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </cofactor>
        <text evidence="1">Binds 1 hybrid [4Fe-2O-2S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HCP family.</text>
    </comment>
    <dbReference type="EC" id="1.7.99.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323898.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KI74"/>
    <dbReference type="SMR" id="B1KI74"/>
    <dbReference type="STRING" id="392500.Swoo_1260"/>
    <dbReference type="EnsemblBacteria" id="ACA85552">
        <property type="protein sequence ID" value="ACA85552"/>
        <property type="gene ID" value="Swoo_1260"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1260"/>
    <dbReference type="eggNOG" id="COG1151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038344_2_0_6"/>
    <dbReference type="OMA" id="CAYAQGM"/>
    <dbReference type="OrthoDB" id="337713at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050418">
        <property type="term" value="F:hydroxylamine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01914">
        <property type="entry name" value="HCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2030">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00069">
        <property type="entry name" value="Hydroxylam_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004137">
        <property type="entry name" value="HCP/CODH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010048">
        <property type="entry name" value="Hydroxylam_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016099">
        <property type="entry name" value="Prismane-like_a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011254">
        <property type="entry name" value="Prismane-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016100">
        <property type="entry name" value="Prismane_a-bundle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30109">
        <property type="entry name" value="PTHR30109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30109:SF0">
        <property type="entry name" value="PTHR30109:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03063">
        <property type="entry name" value="Prismane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000076">
        <property type="entry name" value="HCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56821">
        <property type="entry name" value="SSF56821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01703">
        <property type="entry name" value="hybrid_clust"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0001">2Fe-2S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000092352" description="Hydroxylamine reductase">
        <location>
            <begin position="1"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="3"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via persulfide group" evidence="1">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Cysteine persulfide" evidence="1">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00069"/>
        </source>
    </evidence>
    <sequence length="552" mass="60221" checksum="4DD0C001D35F21A5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI81</accession>
    <name>B1KI81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Trp operon repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrpR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323905.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1267"/>
    <dbReference type="EnsemblBacteria" id="ACA85559">
        <property type="protein sequence ID" value="ACA85559"/>
        <property type="gene ID" value="Swoo_1267"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1267"/>
    <dbReference type="eggNOG" id="COG2973">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147939_0_1_6"/>
    <dbReference type="OMA" id="KHMSLQQ"/>
    <dbReference type="OrthoDB" id="1926997at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000831">
        <property type="entry name" value="Trp_repress"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013335">
        <property type="entry name" value="Trp_repress_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038116">
        <property type="entry name" value="TrpR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38025">
        <property type="entry name" value="PTHR38025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01371">
        <property type="entry name" value="Trp_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003196">
        <property type="entry name" value="Trp_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01321">
        <property type="entry name" value="TrpR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="92" mass="10626" checksum="C0C28F45BC78A126" modified="2008-04-29" version="1">MRAEWDCVLEKVVSHQDHNALIELFELLLTEEERSAIAGRLKVFQVLLLGEMSQRQIAAEYKISIATITRCSNYLKHMSPEQREKIKTLILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY9</accession>
    <name>B1KIY9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1345</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323983.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85637">
        <property type="protein sequence ID" value="ACA85637"/>
        <property type="gene ID" value="Swoo_1345"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1345"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037945_1_1_6"/>
    <dbReference type="OMA" id="GMQDTLT"/>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="274" mass="29705" checksum="5238E9EC6AA3EFC9" modified="2008-04-29" version="1">MENLEGLFEQVPELVVTYGMKILLAIVIFVIGKYLSGLAKKITCKLLLKRKIDETVVSFVGNMAWALVFVFTIVATLGQIGVQTASLVAVIGAAGLAVGLALQGSLSNFASGVLMVLFRPCRVGDYVEAAGIAGTVNEITIFSTKLLTPDNKLIIAPNSAMMDGTIINYSAMDTRRVDLVIGVSYDANLADVRKILTQIVENNQYVLKDPAYTIAVAELADSSVNFVVRPWVKGSDYWPAHFELLEQIKIALDEANIGIPYPQMDLYLKETPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ92</accession>
    <name>B1KJ92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325448.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2837"/>
    <dbReference type="EnsemblBacteria" id="ACA87112">
        <property type="protein sequence ID" value="ACA87112"/>
        <property type="gene ID" value="Swoo_2837"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2837"/>
    <dbReference type="eggNOG" id="ENOG5032EDQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169695_0_0_6"/>
    <dbReference type="OMA" id="GHYASKR"/>
    <dbReference type="OrthoDB" id="2084342at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764953" evidence="2">
        <location>
            <begin position="22"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="13785" checksum="4F9154B1EED4173A" modified="2008-04-29" version="1" precursor="true">MKKYVLLAGLSTALISPNLFAQNLLKDAVRLNRDIKETKAEYKGELRRTEHKLKKARRSAEELADGSYTKHQLSKAERKAAKKVEKIKDGLDPRDEISDKVRRDIKREKRKAINNWLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJJ3</accession>
    <name>B1KJJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324012.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1374"/>
    <dbReference type="EnsemblBacteria" id="ACA85666">
        <property type="protein sequence ID" value="ACA85666"/>
        <property type="gene ID" value="Swoo_1374"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1374"/>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042543_0_0_6"/>
    <dbReference type="OMA" id="NEVLWFM"/>
    <dbReference type="OrthoDB" id="900869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764572" evidence="1">
        <location>
            <begin position="22"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="111"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="374" mass="42842" checksum="FAC8DE935E6933B6" modified="2008-04-29" version="1" precursor="true">MKTILTLSVLGLLFVSQSALASEQNSVTANNESGQLDGRYFDGPYLFYKKGSEQETRDKQHASWICDSTLLTTEINEQQLHRPSNCGELPEPVLNHDAKLVHPDIYTGVKKIVALSDVHGQYDVLIHLLKKQKIIDQNSDWAFGDGHMVMTGDMFDRGHLINEVLWFMYKLDRQASKAGGKLHLLMGNHEQMVMRGDLRYVNERYQTTEKLLNRTYDELYDNSSEIGQWLRSKNTLVKINDSLFLHGGISNEWIERGLNLKKANRLYRANVDKSKEEIRQDPLLNFLFFGNGPTWFRGYFKPDFDENELDKILAYFQVKRVVVGHTSQEQVLGLFDNKVLAIDSSIKNGNSGEILLMKEGHLIRGLYNGERIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR6</accession>
    <name>B1KJR6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating GFA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1447"/>
    <dbReference type="EnsemblBacteria" id="ACA85739">
        <property type="protein sequence ID" value="ACA85739"/>
        <property type="gene ID" value="Swoo_1447"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1447"/>
    <dbReference type="eggNOG" id="COG3791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_4_2_6"/>
    <dbReference type="OMA" id="IWTAGKL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="3"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15184" checksum="439C06A1B60B3B96" modified="2008-04-29" version="1">MVYVGKCLCGEVQIKINGGISDIIHCHCSLCRKNSGTAFATNGFVNAADFEIISGEKSLSTFSFKPGRNRHFCSHCGSPVYSSNEQDPSRYRLRLGILDSDITERPISHNFVSSKASWEELDSKLPRYDSFEPSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ0</accession>
    <name>B1KJZ0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipase_bact_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325513.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2904"/>
    <dbReference type="EnsemblBacteria" id="ACA87177">
        <property type="protein sequence ID" value="ACA87177"/>
        <property type="gene ID" value="Swoo_2904"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2904"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010857_0_0_6"/>
    <dbReference type="OMA" id="RFAKGHH"/>
    <dbReference type="OrthoDB" id="1123563at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020009">
        <property type="entry name" value="Extracell_lipase_Pla-1/cef_e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025920">
        <property type="entry name" value="Lipase_bact_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12262">
        <property type="entry name" value="Lipase_bact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03502">
        <property type="entry name" value="lipase_Pla1_cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipase_bact_N" evidence="1">
        <location>
            <begin position="44"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="823" mass="84898" checksum="071F793366866912" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK01</accession>
    <name>B1KK01_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Indole-3-glycerol phosphate synthase</fullName>
                <shortName evidence="14">IGPS</shortName>
                <ecNumber evidence="14">4.1.1.48</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
                <shortName evidence="15">PRAI</shortName>
                <ecNumber evidence="15">5.3.1.24</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">trpF</name>
        <name evidence="14" type="synonym">trpC</name>
        <name evidence="18" type="ordered locus">Swoo_2915</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 14">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the TrpC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the TrpF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the TrpF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="14"/>
    <dbReference type="EC" id="5.3.1.24" evidence="15"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2915"/>
    <dbReference type="EnsemblBacteria" id="ACA87188">
        <property type="protein sequence ID" value="ACA87188"/>
        <property type="gene ID" value="Swoo_2915"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2915"/>
    <dbReference type="eggNOG" id="COG0134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007713_1_0_6"/>
    <dbReference type="OMA" id="YDIIGIN"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 14" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="15 18" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11 14 18" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="16">
        <location>
            <begin position="13"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="PRAI" evidence="17">
        <location>
            <begin position="263"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACA87188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="476" mass="51841" checksum="AB8377A634D42B82" modified="2008-04-29" version="1">MNQAATNSASNVLTKIVDTKAAHIAALKIRFPEAKLTPKVSDRSLFDALKAPNAGFIFECKKASPSKGLIREHFDVEAIADIYHHYAAGISVLTDEQFFQGDMDYIPKVRARVKQPILCKDFFVDSYQVKLAAHQGADAILLMLSVLNDEQYRTLATEAEKYNLDMLTEVSNEAELKRAIDLNAAIIGINNRNLRDLSTDLGTTQELAPHIPADRVVISESGIYNQAQVRRLSPLVDGFLVGSSLMAEADLDLACRTLTLGHNKVCGLTCSDDILAVAKAGAVYAGLIFYPKSPRSVSREQAQTLVKQHRETGPNIKFVGVFVNEEPKAIAETAKDLDLFAVQLHGSESEYEIEQVRQALKELACPAVIWKAVAVDADKAQQTIQVPANVDRVLFDSKSKQTGEIQFGGTGIAFNWQQSLPNKPASMLAGGLSPELASSASKQGFYGLDFNSGLESAPGVKDHTKINAAFSALREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH7</accession>
    <name>B1KKH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324163.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1529"/>
    <dbReference type="EnsemblBacteria" id="ACA85817">
        <property type="protein sequence ID" value="ACA85817"/>
        <property type="gene ID" value="Swoo_1529"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1529"/>
    <dbReference type="eggNOG" id="COG1639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018569_1_0_6"/>
    <dbReference type="OMA" id="YWTKRIS"/>
    <dbReference type="OrthoDB" id="935550at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="28"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="494" mass="54842" checksum="4510C32792FE2461" modified="2008-04-29" version="1">MKSTNQTLSHPKSKGIDYWTKRISDQEMPALCSTVKTLEKLEKDDVSSLSILGKSVIHDNALTSRILRVANSATYSKGNSQITTVSRATVMLGFDNIRSICITAKLLSSLLESDGLTPNVYQRLLKLMARAFQAAMLAKMMLREHEEELQEEVFIASLLYHLGESAFWSTGSEEAIALDTSISQCCDAKEEKTVIRENLGTSFNMLSQGIARAWGLGEVLQKALSSPDARTPEIRSIFLANEICEILSQSTPSPSELQHRLQQTATMLDIEVDELKGRMIRCSKATKKLAEAYGAKVLLEYLPNPKLLTKDLEVEKDKPALRVPNMAEQLKKLRALTDCAVTKADFNQVITITLEGILLGVGVDRCGVLLLSPNRKQLQPRIVLGDGAEQMKNEFIISLEQKKCLFSESIELKQSMFVDEPDSAKWRLYMDDDLKSKVSSKGFMLAPLIVEKKVIGMIYADRASSARSLGQPEFDNFTHFSNLANLCLTAALGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKL2</accession>
    <name>B1KKL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87229">
        <property type="protein sequence ID" value="ACA87229"/>
        <property type="gene ID" value="Swoo_2956"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2956"/>
    <dbReference type="HOGENOM" id="CLU_2119456_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12720" checksum="2DE2374ABF29E3A6" modified="2008-04-29" version="1">MTSKEEVIKFLKSCSECELLSVVQALSEEKRYLNRDGSRERVTRRYLLASTCYDIEGEDVVGDPTFSFIGMPQDGENWLSSAADAGICPRCKSEVRGFCTHSICPVCDRNVALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKU1</accession>
    <name>B1KKU1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327073.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4496"/>
    <dbReference type="EnsemblBacteria" id="ACA88747">
        <property type="protein sequence ID" value="ACA88747"/>
        <property type="gene ID" value="Swoo_4496"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4496"/>
    <dbReference type="eggNOG" id="ENOG5032XHJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_754188_0_0_6"/>
    <dbReference type="OMA" id="EPASWYY"/>
    <dbReference type="OrthoDB" id="1247873at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="367" mass="41506" checksum="56850A233D1D7FC0" modified="2008-04-29" version="1" precursor="true">MRRSVKFRLIFLISAIVSYSLGFQFLPESLDGDLNLRLVIGFSVLYFILLPLSYWFCIIKVGEQKLWKMLLIFSLSSLIARLSFPAEIAGYFEFIAWLRYPIIAVLLAIQLFLMVSIVKGLWQARNLSGDPRVHILETFQEQDDKKRSLALVMASEPASWYYAIPYLSRNHIPAITSLKLRSSSLWCWFLLILGTLATASLAYFVIEPWSQLAAIIVASIISYSLVMVTANYRLSRHYSLYCQHENLIINNSVWGFMSIKLTDIADIEIGEYSRKENKEGLHFGYGASSNIKLNFKQPQTYFGGLGQLTEQVDSIDMHLVDPQALVEYFQQYIANQSGVPLPTDGATTQELQTCDSPAISAELSSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY4</accession>
    <name>B1KKY4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cell division protein FtsL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsL</name>
        <name evidence="7" type="ordered locus">Swoo_4540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="6">Localizes to the division septum where it forms a ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the FtsL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327116.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4540"/>
    <dbReference type="EnsemblBacteria" id="ACA88790">
        <property type="protein sequence ID" value="ACA88790"/>
        <property type="gene ID" value="Swoo_4540"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4540"/>
    <dbReference type="eggNOG" id="COG3116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156524_2_0_6"/>
    <dbReference type="OMA" id="DLWHHKW"/>
    <dbReference type="OrthoDB" id="1803426at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00910">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011922">
        <property type="entry name" value="Cell_div_FtsL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37479">
        <property type="entry name" value="PTHR37479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04999">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02209">
        <property type="entry name" value="ftsL_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="104" mass="12358" checksum="9FB297AF39616F2A" modified="2008-04-29" version="1">MSQPQFNLPKIVLLDLWHHKWVLLLACAVLGNAITVVYTSHVTRKYTSQWDQMLQERDRLDIEWRNLLLEEQSQSEHSRITRIASKELEMNRPLPKEEIVVRVP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ2</accession>
    <name>LEUC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="1">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alpha-IPM isomerase</fullName>
            <shortName evidence="1">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuC</name>
        <name type="ordered locus">Swoo_4548</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327124.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKZ2"/>
    <dbReference type="SMR" id="B1KKZ2"/>
    <dbReference type="STRING" id="392500.Swoo_4548"/>
    <dbReference type="EnsemblBacteria" id="ACA88798">
        <property type="protein sequence ID" value="ACA88798"/>
        <property type="gene ID" value="Swoo_4548"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4548"/>
    <dbReference type="eggNOG" id="COG0065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_4_6"/>
    <dbReference type="OMA" id="CNMSIEM"/>
    <dbReference type="OrthoDB" id="749418at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0432">Leucine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000135715" description="3-isopropylmalate dehydratase large subunit">
        <location>
            <begin position="1"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <sequence length="466" mass="49707" checksum="876573C775DCB473" modified="2008-04-29" version="1">MAKTLYEKVWDSHVVVANEGEAPLIYVDRHLVHEVTSPQAFSGLKVAGRRLRAPEKTFATMDHNTSTKSASLDALSPMARIQVETLQDNCKEFGIKLYDIHHKNQGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVMATQTLRQNKAKTMKIEVKGHVTPGITAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMIAPDATTAEYLKGREFAPKAESWEQAIEAWSELKTDADAVFDSTVILEAADIAPQLTWGTNPGQVVAIDGVVPNPQDEPNATVKASIEKALEYVALSAGTSMKDVSINKVFIGSCTNSRIEDLRDAALHAKGKHVAEGVTAIVVPGSGLVKEQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNDDRLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAVAGHFVDIRQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL37</accession>
    <name>B1KL37_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322727.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0077"/>
    <dbReference type="EnsemblBacteria" id="ACA84378">
        <property type="protein sequence ID" value="ACA84378"/>
        <property type="gene ID" value="Swoo_0077"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0077"/>
    <dbReference type="eggNOG" id="ENOG502Z9E6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042404_0_0_6"/>
    <dbReference type="OMA" id="ASRIMQW"/>
    <dbReference type="OrthoDB" id="514419at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026950">
        <property type="entry name" value="Caps_assemb_Wzi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038636">
        <property type="entry name" value="Wzi_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14052">
        <property type="entry name" value="Caps_assemb_Wzi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765017" evidence="1">
        <location>
            <begin position="29"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="501" mass="56004" checksum="92017C128A1883DC" modified="2008-04-29" version="1" precursor="true">MLKSYSTKLIAVFLFCTSLLSASFAALSAPWVDVSDIYLRADIQALADEGVITVPVNTYPLMWSGIAVDLDKVEPSTLTPALAKAFARVNFYYRNAVGNKGNTRIKAAAATDPARFQHFGSDYREKGELQVSHEYLGERFAYKIAASANYDATDDKEFRLDDSYIAMALGNWMFTAGAIEQWWGPGFDSAMHRSNNARPLPSVMVTRNNAAAFETPWLSWLGPWTLTAGVSRLEEERAIANPLLWNFRSSLRPFRQLEIGFSWATQFCGEGEECSFKSALKSITGQRDCRAENVGEVGCSSYGNQMAGYDVRFSDTWFNVPFGIYYEKTCEDANGSAPWDIVDCGHAAGLDTRFSSDSAQYRLFFEYTDTMVACGADDNVFNCMYEHSEYKSGSRYYGKTYGSTYESDAIVYALGLIGQFENSKGLTSIVRYAQLNKDGSSRNNGWAPQSPKEDLLMLELSYRMPIWQGMMSVGGTVSQSEFEVEDKKTDATLFGTYEYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL78</accession>
    <name>B1KL78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322768.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0118"/>
    <dbReference type="EnsemblBacteria" id="ACA84419">
        <property type="protein sequence ID" value="ACA84419"/>
        <property type="gene ID" value="Swoo_0118"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0118"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_6"/>
    <dbReference type="OMA" id="EKWTGIG"/>
    <dbReference type="OrthoDB" id="1377545at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="28801" checksum="7E1D305E4132591A" modified="2008-04-29" version="1">MKKVILITGSTDGIGLETAKALVSNGHHVLIHGRNPTKLADVSEILSGLAGAGVVESYCSDLSNLSDVEALADTIMDKHQKIDVLINNAGVYKTVKIDTEDGLDVRFVVNTIAPFLLTQRLVDLFDTSGRIINLSSAAQSHVDLDSLTRPNNDIEDSNIYAQSKLGLIMWSIYMAEQYKEKGPAIISLNPASLLGSKMVKEAYGIKGGDLNIGVDILCRAALSDEFANASGRYFDNDVGRFTSPHPDALNTSKNKALVAKIKSVLANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL93</accession>
    <name>B1KL93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322783.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84434">
        <property type="protein sequence ID" value="ACA84434"/>
        <property type="gene ID" value="Swoo_0133"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0133"/>
    <dbReference type="eggNOG" id="ENOG5032SBD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1524132_0_0_6"/>
    <dbReference type="OrthoDB" id="1987097at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="176" mass="20192" checksum="4488553AE7150191" modified="2008-04-29" version="1">MVSRRNLKQEHELAVLNSFADHLKLEGKSLEILEQPDPPEAIVNIDKTKTWIEITDAFLDEEHARSLMNSIADDVPHIVDETRDEAEIEPDFQSVVHGVIAKKYDKKTMLQAHRTFGRGILLVGIFTPFNSASGIADEERENIRELVDNKAKAIFDKIYVYDGTLKHKFYLLFEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB5</accession>
    <name>B1KLB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324186.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85840">
        <property type="protein sequence ID" value="ACA85840"/>
        <property type="gene ID" value="Swoo_1552"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1552"/>
    <dbReference type="eggNOG" id="ENOG5033BWI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789284_0_0_6"/>
    <dbReference type="OMA" id="HRINNIN"/>
    <dbReference type="OrthoDB" id="1505503at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="352" mass="41476" checksum="066275E5D40F3806" modified="2008-04-29" version="1">MEYVVYEFPDYAEQVINLLLEEDWLIHSFSLNDEKEIFNPSAYLYNSEMSGVEYAIHLDLNIYQYILNAFKKEKKNKLHRSAIALVVFAKFTNVKFDPTIAIYEKLNYKNQCPDELIDDLILFRQIDNAEMDHLAEFVLSETDSIKLPNPACLDRSQLNEKLTEYRRLKKWDTLYVLVLKLTELYFCDRGLSNEDKLEVFWRWCHEEFLFSLVATCLAIKLFGKQRIPKLMKYAPRHSAEINKKHLINMTWDLFLLDKFFENWVNKPDQQEFIYASNDKPFQEVLKTAIEVQSNGVDVILNRDLSPALIKSFLTTFEQVMTKQGRSISSVTDFQSFREGLIVDYESALKVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV4</accession>
    <name>B1KLV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327159.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4584"/>
    <dbReference type="EnsemblBacteria" id="ACA88834">
        <property type="protein sequence ID" value="ACA88834"/>
        <property type="gene ID" value="Swoo_4584"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4584"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_7_1_6"/>
    <dbReference type="OMA" id="ATDKAPQ"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="127" mass="13646" checksum="2F60159723B4DE19" modified="2008-04-29" version="1">MANKSIIATDKAPQAIGTYSQAVKVGSTVYLSGQIPLDPASMQIVSGEFNAQVVQVFENLTAVCEAAGGSLNDIVKLNIFMTDLSNFATVNEIMERYFDQPFPARAAIGVKQLPKDSLVEMDGVMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLX9</accession>
    <name>B1KLX9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327184.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4609"/>
    <dbReference type="EnsemblBacteria" id="ACA88859">
        <property type="protein sequence ID" value="ACA88859"/>
        <property type="gene ID" value="Swoo_4609"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4609"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_0_6"/>
    <dbReference type="OMA" id="DSSDAHH"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="4">
        <location>
            <begin position="55"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="397" mass="42188" checksum="2CE0A721773DB09E" modified="2008-04-29" version="1">MTKIAISHMGLCTPLGQDQKQVLTRLIQGDTGAMLHRDNLIPESNTLVGEVSEPLPQIPASLSKFESRNNQLLLSAAKQITGAVMQACKQYGPQRIGIVLGTSTSGIATGEDALAHNAKHNSFPDGYHYSQQELGNSSDFLKALFNISGPCYTVSTACSSSAKVFSSARRLLEADLCDMVIVGGSDSLCKLTLNGFNSLESVSKGHCQPFSANRDGINIGEGAALFTLERGEAEIMLAGIGESSDAHHISAPHPEGRGAVSAIKAALDDAQIPPQKISYINLHGTATRKNDAMESRALTQVFGEQTPPCSSTKPLVGHTLGAAGAIEAAFCYLLLSSLNTEQRLPPQIWDQDSDLDDPSLPLVNKNQTAELHYLMSNSFAFGGSNASLIFCRGKDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM30</accession>
    <name>B1KM30_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Heme exporter protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_4660</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the CcmB/CycW/HelB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327234.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4660"/>
    <dbReference type="EnsemblBacteria" id="ACA88910">
        <property type="protein sequence ID" value="ACA88910"/>
        <property type="gene ID" value="Swoo_4660"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4660"/>
    <dbReference type="eggNOG" id="COG2386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079069_1_0_6"/>
    <dbReference type="OMA" id="VKCLAHW"/>
    <dbReference type="OrthoDB" id="1886257at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003544">
        <property type="entry name" value="Cyt_c_biogenesis_CcmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026031">
        <property type="entry name" value="Cyt_c_CcmB_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30070">
        <property type="entry name" value="PTHR30070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03379">
        <property type="entry name" value="CcmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002764">
        <property type="entry name" value="CcmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01190">
        <property type="entry name" value="ccmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="11 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA88910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="228" mass="24059" checksum="6F5FDD6D281C9346" modified="2008-04-29" version="1">MKKGISFRQAFFTLLKRDLQIAIRHKGDIFNPLLFFILVVTLFPLGIGPEPQVLSRVAPGVIWVAALLASMLSLERLFKADYADGSLEQMLLSPQPLPLMVLAKVLAHWLLTGVPLILVAPLLAVLLHLDGNSYGALIATLALGTPVLSLLGAIGVALTVGLHKGGVLLSLLILPLYIPVLIFATTAIDAAGLNLPYSGHLAIIGAMLVGSLILAPFAIGASLRVSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM52</accession>
    <name>B1KM52_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322814.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0164"/>
    <dbReference type="EnsemblBacteria" id="ACA84465">
        <property type="protein sequence ID" value="ACA84465"/>
        <property type="gene ID" value="Swoo_0164"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0164"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_280043_0_0_6"/>
    <dbReference type="OMA" id="MMADADY"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="626"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="845"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="608"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1123" mass="122549" checksum="B1A0C53349587879" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG8</accession>
    <name>B1KMG8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 5">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324312.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1681"/>
    <dbReference type="EnsemblBacteria" id="ACA85966">
        <property type="protein sequence ID" value="ACA85966"/>
        <property type="gene ID" value="Swoo_1681"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1681"/>
    <dbReference type="eggNOG" id="COG1209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_9_0_6"/>
    <dbReference type="OMA" id="PFIMYLG"/>
    <dbReference type="OrthoDB" id="1004719at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="292" mass="32210" checksum="79621DB405590B54" modified="2008-04-29" version="1">MKGIILAGGTGTRLYPLTKVVSKQLLPIYDKPMIYYPLATLMSAGIRDILIITTPDDIESFKSLLGTGSDWGVSIEYQIQVSPDGLAQAFLLGESFIGDDSVALILGDNLFYGHDLIKSLKRAAKGKVGATVFGYHVSNPCDYGVVEFDNENRVISIEEKPQSPKSNYAIPGIYFFDNKVIDFAKKVTPSDRGELEITEVIGQYLAAGFLNVEIMGRGTAWLDTGTYDSLLQAAQFIETIDKRQGLKVNCPEEMAYRMGYIDDKQLLALAEPLRKSGYGEYLISILSQRVFS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNC9</accession>
    <name>CINAL_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CinA-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_0325</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CinA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322975.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNC9"/>
    <dbReference type="SMR" id="B1KNC9"/>
    <dbReference type="STRING" id="392500.Swoo_0325"/>
    <dbReference type="PRIDE" id="B1KNC9"/>
    <dbReference type="EnsemblBacteria" id="ACA84626">
        <property type="protein sequence ID" value="ACA84626"/>
        <property type="gene ID" value="Swoo_0325"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0325"/>
    <dbReference type="eggNOG" id="COG1058">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030805_9_3_6"/>
    <dbReference type="OMA" id="PGVPYEM"/>
    <dbReference type="OrthoDB" id="1834406at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00226_B">
        <property type="entry name" value="CinA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008135">
        <property type="entry name" value="Competence-induced_CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006728">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00200">
        <property type="entry name" value="cinA_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000100333" description="CinA-like protein">
        <location>
            <begin position="1"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00226"/>
        </source>
    </evidence>
    <sequence length="424" mass="45718" checksum="5E85085E4F9A864F" modified="2008-04-29" version="1">MKLEMICTGEEVLAGQIVDTNAAWFANTLIERGVECQRRITVGDRLEDLVAVFKERSTEADVIMVNGGLGPTSDDLSTEAMALALGVPLVENKEWRSKLEAWFAKNARVMAESNLKQALLPQGAIMIDNPVGTACGFAIKLNQAWLFFTPGVPFEFKRMVKEQFIPFIEEHFPLSEPVSVKKLLTLGHGESALADKLEVIPLPKGVTLGYRSYMPYIEIKLFARGQLAIDSLATIETEVKKILGHSVVAEDITTLDQEIHNSLVNSGFSLSVAESCTGGLIASGLVAFAGSSAYLHQGLVTYSNEAKVKVLGVNPQTLDDYGAVSIATVEEMAKGARGILDSDYALATSGIAGPDGGSDEKPVGTVAIALATKYGVYSQMLKLPSRSRALVRSLGTAIAYDMLRRELLGEAVIVDYSSFSRFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNH4</accession>
    <name>B1KNH4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324397.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1767"/>
    <dbReference type="EnsemblBacteria" id="ACA86051">
        <property type="protein sequence ID" value="ACA86051"/>
        <property type="gene ID" value="Swoo_1767"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1767"/>
    <dbReference type="eggNOG" id="ENOG50333JI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172471_0_0_6"/>
    <dbReference type="OMA" id="TCSAENM"/>
    <dbReference type="OrthoDB" id="2044709at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019620">
        <property type="entry name" value="Metal-bd_prot_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10678">
        <property type="entry name" value="DUF2492"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03853">
        <property type="entry name" value="matur_matur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="80" mass="9075" checksum="A0545ED1AFEED213" modified="2008-04-29" version="1">MTQSIHGHQVMELMLALNKAISKEELKLLMLRQFGASAKYHTCSACEMSADELIILLERKGKFIISERGVETAREKICNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI1</accession>
    <name>B1KNI1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1774</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324404.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1774"/>
    <dbReference type="EnsemblBacteria" id="ACA86058">
        <property type="protein sequence ID" value="ACA86058"/>
        <property type="gene ID" value="Swoo_1774"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1774"/>
    <dbReference type="eggNOG" id="COG1045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_10_0_6"/>
    <dbReference type="OMA" id="GDDVMLY"/>
    <dbReference type="OrthoDB" id="1639008at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="273" mass="29799" checksum="C78C9540E44520B3" modified="2008-04-29" version="1">MGVIARIKDDIASIYHRDPAAHGTLEILLNYPGMQAIWIHRVSHKLWLSQWRLLSRCLSTFSRWLTGVEIHPGARIGDRFFIDHGMGVVIGETAEIGDDCTLYHGVTLGGTTWQSGKRHPTLGNNVVIGAGAQVLGPITMHDGARVGSNSVVVKDVPKDTTVVGIPGRVVATPNDVTKEQTKRRSEMAKKYGFDAYAVSPDNPDPVANAIGQMLDHMHLMDSKVQEVCQAVQSMGGSVCTDKLPELEVDEFSDAEHAAAQKRKKAIDEFDPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI5</accession>
    <name>B1KNI5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-binding protein IscA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Iron-sulfur cluster assembly protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1778</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324408.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1778"/>
    <dbReference type="EnsemblBacteria" id="ACA86062">
        <property type="protein sequence ID" value="ACA86062"/>
        <property type="gene ID" value="Swoo_1778"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1778"/>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069054_5_1_6"/>
    <dbReference type="OMA" id="GYQYGMA"/>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011302">
        <property type="entry name" value="IscA_proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02011">
        <property type="entry name" value="IscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="107" mass="11565" checksum="2568ADB06A79435D" modified="2008-04-29" version="1">MAISMTPAAAERVKSFLDSRGKGIGLRLGLKTSGCSGMAYIIEFVDDLNADDEVYEIDGVKIIIDAKSFIYLQGIELDFVKEGLNEGFQFNNPNAKGECGCGESFTV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNJ9</accession>
    <name>APT_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="1">APRT</shortName>
            <ecNumber evidence="1">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">apt</name>
        <name type="ordered locus">Swoo_1792</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324422.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNJ9"/>
    <dbReference type="SMR" id="B1KNJ9"/>
    <dbReference type="STRING" id="392500.Swoo_1792"/>
    <dbReference type="EnsemblBacteria" id="ACA86076">
        <property type="protein sequence ID" value="ACA86076"/>
        <property type="gene ID" value="Swoo_1792"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1792"/>
    <dbReference type="eggNOG" id="COG0503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063339_3_0_6"/>
    <dbReference type="OMA" id="KPGIVFR"/>
    <dbReference type="OrthoDB" id="1532478at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00103">
        <property type="entry name" value="PUR_PYR_PR_TRANSFER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0660">Purine salvage</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000089006" description="Adenine phosphoribosyltransferase">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <sequence length="181" mass="19931" checksum="D0B75986B5DC3C8A" modified="2008-04-29" version="1">MNNDSLAIIKQSIKTIPDYPKPGILFRDVTSLLEDHTAYKATMDILVQHYKDHGFTKIVGTEARGFLFGAPLALELGVGFVPVRKPGKLPRETISESYELEYGHDVLELHTDAINENDKVLVVDDLLATGGTIEATVKLIRKLGGEVKHAAFVISLPDLGGAKRLEEMDLELVTLCEFEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ0</accession>
    <name>B1KNQ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325844.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3238"/>
    <dbReference type="EnsemblBacteria" id="ACA87508">
        <property type="protein sequence ID" value="ACA87508"/>
        <property type="gene ID" value="Swoo_3238"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3238"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004881_0_0_6"/>
    <dbReference type="OMA" id="IIDEHSH"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="359"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="864"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1021" mass="113834" checksum="12847E034275A7EA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ1</accession>
    <name>B1KNQ1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydro-rel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325845.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3239"/>
    <dbReference type="EnsemblBacteria" id="ACA87509">
        <property type="protein sequence ID" value="ACA87509"/>
        <property type="gene ID" value="Swoo_3239"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3239"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046987_1_0_6"/>
    <dbReference type="OMA" id="AWNWEDA"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767246" description="Amidohydro-rel domain-containing protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="354"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="435" mass="48165" checksum="CE671E65D68B2505" modified="2008-04-29" version="1" precursor="true">MKKLTVLNQVVSSNTLTLSVLVCSALSSTVFAHDIVPATAQSNSIIFKNATVHTVIDGVKHNTNLFIQDGFIKAIGPEISAPEALIFDASNKHIYPGLIALDTSMGLVEVEMMRPSNDSYDIGLSNPQLEAITAFNPDSEIIPTVRVNGITHAQVVPQGERLAGQSALVSMDSWTIEDALVPSTMGFHLYWPKQGALPQDEKKREKQLKQHRKDLKQLATIFEEGYRYSLASKAKKLSKQDIRWQSMLPLYQGDAQLFVHANRQKQIEEAVSLAKQYGFKLVIVGGYDAWRLCELLNEIEAKVIYTKTLSLPMRKDEPLEMSFKIPALLKQANIPFALGFTSDWNSRNLPLAAGQTVAYGLSKEEALQSITLDAAKILGAESMGALAPGYAANLVISGGDILDPMMTKIEKVYIDGREVDLNNRQQQLYQKYLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNT9</accession>
    <name>B1KNT9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)</fullName>
            <ecNumber evidence="3">2.5.1.31</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ditrans,polycis-undecaprenylcistransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Undecaprenyl diphosphate synthase</fullName>
            <shortName evidence="3">UDS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Undecaprenyl pyrophosphate synthase</fullName>
            <shortName evidence="3">UPP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">uppS</name>
        <name evidence="4" type="ordered locus">Swoo_3277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.31" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325883.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3277"/>
    <dbReference type="EnsemblBacteria" id="ACA87547">
        <property type="protein sequence ID" value="ACA87547"/>
        <property type="gene ID" value="Swoo_3277"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3277"/>
    <dbReference type="eggNOG" id="COG0020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038505_1_1_6"/>
    <dbReference type="OMA" id="PRTEGHK"/>
    <dbReference type="OrthoDB" id="1630604at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008834">
        <property type="term" value="F:di-trans,poly-cis-decaprenylcistransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="34"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="207"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="264" mass="29713" checksum="351AD45A1E65C0ED" modified="2008-04-29" version="1">MSIDSQSGPEFSAEELAELVKLSIPKHVAIIMDGNGRWAQAQGKPRVMGHKAGVKTVRRAVSTAREMGIDSLTLFAFSSENWRRPDKEVTLLMELFFTVLQREIKLLHKNGVRLNIIGDISRFSERLQKQIAAAEEKTAENTGMVLNVAANYGGRWDIMQAAKTLAEKVQSGEMNSNQFTEEALSQHLSMQNQPEVDLMIRTGGDYRISNFVLWQAAYAELVFTDTLWPDFDEHAFKQAVATFASRQRRFGLTGCQIESLQENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNW8</accession>
    <name>B1KNW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325912.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3307"/>
    <dbReference type="EnsemblBacteria" id="ACA87576">
        <property type="protein sequence ID" value="ACA87576"/>
        <property type="gene ID" value="Swoo_3307"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3307"/>
    <dbReference type="eggNOG" id="ENOG5033AQ3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159285_2_1_6"/>
    <dbReference type="OMA" id="WAFYART"/>
    <dbReference type="OrthoDB" id="2093867at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="10809" checksum="6A451A7ED0875FA5" modified="2008-04-29" version="1">MAFVNLKWPELLSKPSVDIFSRSLAAIFGGYLVAATACGLLALALPLPVAQSVLTAMMLSFALYTIAALWAFSVKRSRQAWRDLLCISTLFYLLILLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX6</accession>
    <name>B1KNX6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327324.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4758"/>
    <dbReference type="EnsemblBacteria" id="ACA89007">
        <property type="protein sequence ID" value="ACA89007"/>
        <property type="gene ID" value="Swoo_4758"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4758"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065741_0_0_6"/>
    <dbReference type="OMA" id="QCHFGQD"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="52"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="264" mass="29938" checksum="A73150DDC3CA2D99" modified="2008-04-29" version="1">MDYLAVNKSAWDKRTKVHVGSKFYDVDGFLSGNSALQEIEFEELDVKGKSLLHLQCHFGLDTLSWAREGAEVTGIDLSSVAIEQARELAVKSQLEANFICSDLYSAADKLERQFDIVFTSYGAICWLPDLNRWAQMIKQSLKPGGEFYMAEFHPLEALFDGYSYFAQDEPDVDEEGTYTENCSGEKETLVSWPHPISEVFNALIAAGLEIKRYNEFDFSPYDAFANLEKELVTDKNGKQHTRYAMKHNDQRVPLVYSISAINNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP17</accession>
    <name>B1KP17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4799</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327365.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4799"/>
    <dbReference type="EnsemblBacteria" id="ACA89048">
        <property type="protein sequence ID" value="ACA89048"/>
        <property type="gene ID" value="Swoo_4799"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4799"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_0_6"/>
    <dbReference type="OMA" id="DRPRPCH"/>
    <dbReference type="OrthoDB" id="1030724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="4">
        <location>
            <begin position="3"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="30222" checksum="5EE0EB19BB5D2A4F" modified="2008-04-29" version="1">MANILLVANLNCDRILNLDRPLQMGGRFHYQDGGQRLGGGGANTGIGLVWAKHRVALVSQVGRDKVGDWLLAEASTQGIDCHLIQRHKENSCEMLLVMTPDGERTIIRPQRPVFELASPPVWQQWDAVYFNSSAEGSVSWAKTALKNCLVLAQLAKDERPRPCDILIASKTDMQGRSQLSPWEYGLTIAGDSLKYFIVTDGADGAYLYTENDCQQVEATPSEVIDTTGAGDAYAAGLIHGLTTGLGILESMKEAGVWAGFAVATQSSIPGEGLKQYLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD3</accession>
    <name>B1KPD3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323052.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84703">
        <property type="protein sequence ID" value="ACA84703"/>
        <property type="gene ID" value="Swoo_0404"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0404"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1501363_0_0_6"/>
    <dbReference type="OMA" id="KQEQYSW"/>
    <dbReference type="OrthoDB" id="2018542at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765107" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="9"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="21307" checksum="DED529B0495D414D" modified="2008-04-29" version="1" precursor="true">MKKQSLAVAAVLATAISAPSMAADWFVGGAVGYQQDTYKIKETENGATESDKAKEKDMSYQLRVGTYLNDNNRVYGTYSYNSDDFAKQQSFLASYDYLVPLGAGKKLNWFVGATAGMNHTSPDFDELSSKNTFVWGGQTGLMYKINDKLSTEIGYRYLKQDYDVSASDTDYSAKFSLNDTQQVYLGVDYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE2</accession>
    <name>B1KPE2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KAP P-loop domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323061.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84712">
        <property type="protein sequence ID" value="ACA84712"/>
        <property type="gene ID" value="Swoo_0414"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0414"/>
    <dbReference type="eggNOG" id="COG4928">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039725_1_0_6"/>
    <dbReference type="OMA" id="TISNMPR"/>
    <dbReference type="OrthoDB" id="1668340at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011646">
        <property type="entry name" value="KAP_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07693">
        <property type="entry name" value="KAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KAP NTPase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="565" mass="64280" checksum="CC394337F74B9D1C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE3</accession>
    <name>B1KPE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323062.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84713">
        <property type="protein sequence ID" value="ACA84713"/>
        <property type="gene ID" value="Swoo_0415"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0415"/>
    <dbReference type="eggNOG" id="ENOG502ZBJB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047556_0_0_6"/>
    <dbReference type="OMA" id="WISNISI"/>
    <dbReference type="OrthoDB" id="1425983at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="461" mass="52732" checksum="26A45EC63D765F78" modified="2008-04-29" version="1">MGSIEIELEPEVSHLSAEQIEELYQKYLSGVKNSELIEEFSIETNPNKLIKLLPPLLRDDCQCDYCDLPMLQKRKSKSGYSSAHPIECSACGHEVYENSYSNQQCRCKQCAQKRLEAKRVKELEDREKIESHYSVESKQPLPYSSLNFLEKLILLTLFRDHTDGEFDCILSLNDSVRVDPLCPTESMTNEFIAHLYEAKVIVVDPKSRFSAFNEEEDFESFYPLRVQWISNISIDAGTRADLKTLHLAIYRDLRENDKQSWGEELYGLLYLIATEEVLQYLYYKADELDVQFGADKKAREVIQVLLENFSVSQIYYFVRKAVDNAHLFYSKGYSTGKKHAGNTIPNKMMSLGERALKGEWSMYPSSRVSACPRSALSKVLFDLLLEDEDAGFTKSPELYWMDELHPLFNSSEVGEFKPKPADEHGLACLECSSKAVKADMSNDRVALICHDCGAVHEFKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM4</accession>
    <name>B1KPM4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324523.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1893"/>
    <dbReference type="EnsemblBacteria" id="ACA86177">
        <property type="protein sequence ID" value="ACA86177"/>
        <property type="gene ID" value="Swoo_1893"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1893"/>
    <dbReference type="eggNOG" id="ENOG502ZC7J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109815_0_0_6"/>
    <dbReference type="OMA" id="ICRIEAC"/>
    <dbReference type="OrthoDB" id="1482023at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="23095" checksum="B1292517B804B9DE" modified="2008-04-29" version="1">MSRKRTKVSQYYVIAAVVAAELNHTLTYCKQINLTASNAQAASSRVGNAALGFKALTGFIDDLACYTMKAATDINLLANQASKMATETARAASALKHFEKAKRNSHDAKYAKTILPAFQHTSDRYAQLQRSFQKVINQMEVQLHELKRNLRTANILASICRIEACRVDVANQATFNDVANRVDNVANKIRQRVDNAISLFDTSAEKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM6</accession>
    <name>B1KPM6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1895"/>
    <dbReference type="EnsemblBacteria" id="ACA86179">
        <property type="protein sequence ID" value="ACA86179"/>
        <property type="gene ID" value="Swoo_1895"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1895"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_1_0_6"/>
    <dbReference type="OMA" id="ELWKLWY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="198" mass="22551" checksum="E1BAA7F810126E9C" modified="2008-04-29" version="1">MANEIKTEFLSGECIVLEPMTIEHTAALSLAASDGELWNIWYTDVPHPDEMKQYIEAAIASEKAGEALTFVVRDKVSGEVIGSTRICRWDQSNRRLEIGYTWYAKRAQRTGVNTEAKLLLLTYAFETLDVMAVEFRTHWHNQAAREAITRLGAKQDGVLRNHQLLADGTVRDTVIYSIIDKEWETVKDNLMKRVAQYS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS7</accession>
    <name>MUTS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mutS</name>
        <name type="ordered locus">Swoo_3341</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325945.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPS7"/>
    <dbReference type="SMR" id="B1KPS7"/>
    <dbReference type="STRING" id="392500.Swoo_3341"/>
    <dbReference type="EnsemblBacteria" id="ACA87610">
        <property type="protein sequence ID" value="ACA87610"/>
        <property type="gene ID" value="Swoo_3341"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3341"/>
    <dbReference type="eggNOG" id="COG0249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_4_0_6"/>
    <dbReference type="OMA" id="TPMMAQY"/>
    <dbReference type="OrthoDB" id="15991at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000093646" description="DNA mismatch repair protein MutS">
        <location>
            <begin position="1"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="618"/>
            <end position="625"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <sequence length="858" mass="95444" checksum="6A606B85969E3B21" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT6</accession>
    <name>ENO_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enolase</fullName>
            <ecNumber evidence="1">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">eno</name>
        <name type="ordered locus">Swoo_3350</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
        <text evidence="1">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325954.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPT6"/>
    <dbReference type="SMR" id="B1KPT6"/>
    <dbReference type="STRING" id="392500.Swoo_3350"/>
    <dbReference type="EnsemblBacteria" id="ACA87619">
        <property type="protein sequence ID" value="ACA87619"/>
        <property type="gene ID" value="Swoo_3350"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3350"/>
    <dbReference type="eggNOG" id="COG0148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031223_2_1_6"/>
    <dbReference type="OMA" id="EFMIIPV"/>
    <dbReference type="OrthoDB" id="533698at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <feature type="chain" id="PRO_1000115914" description="Enolase">
        <location>
            <begin position="1"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="1">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="368"/>
            <end position="371"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <sequence length="431" mass="45912" checksum="DD0B57D4A4E161D7" modified="2008-04-29" version="1">MAKIINVIGREIMDSRGNPTVEAEVHLEGGFNGMAAAPSGASTGSREALELRDGDKARYLGKGVLTAVANINGPIRDALMGKDATAQAELDQLMIDLDGTENKDKLGANAILAVSLAAAKAAAAFKGMPLYAHIAELNGTPGQFSMPVPMMNILNGGEHADNNVDIQEFMVQPVGAKTFREALRVGAEIFHSLKKVLQEKGLSTSVGDEGGFAPNLASNADALAMIKVAVEKAGYKLGEDVTLALDCAASEFYKDGQYDLTGEGKVFSANGFSDFLKSLTEEYPIASIEDGLDESDWEGWAYQTQIMGDKIQLVGDDLFVTNTKILKRGIDNNIANSILIKFNQIGSLTETLAAIRMAKEAGYTVVISHRSGETEDATIADLAVATSAGQIKTGSLCRSDRVAKYNQLLRIEEQLGEKAPYRGRSEIKGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW0</accession>
    <name>B1KPW0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidohydrolase</fullName>
            <ecNumber evidence="4">3.5.1.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3374</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.32" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325978.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87643">
        <property type="protein sequence ID" value="ACA87643"/>
        <property type="gene ID" value="Swoo_3374"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3374"/>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_6_0_6"/>
    <dbReference type="OMA" id="MKMHACG"/>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047980">
        <property type="term" value="F:hippurate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767287" evidence="2">
        <location>
            <begin position="29"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="218"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="47302" checksum="267EB58485B97D9C" modified="2008-04-29" version="1" precursor="true">MRLTKNTIALALTLGVTTSLSSIFSVQALELSDSVAQAMPKLEKLYLHLHQNPELSYQEKATGQRMAKELSKLGFEVTDNYGGYGVVGIFENGEGPVVMIRADTDGLPIIEETGKSYASTVTTTDVAGKTVGVMHGCGHDIHMTSMIGAAEQLVKQKNNWKGTLMVVAQPAEEVGGGAKAMLKQGLFKQFPTPDKVLGLHVSASIPAGKVAVVSGYALANVDSVDITIKGKGGHGAYPHLTIDPVVLAARTVLALQTIPSREISPLEPNVVTVGSIHGGSKHNIISNEVKLQLTLRSYNPEVRLQQIAAIERLTKGIAVSAGLPDELMPLVYVHNDETVPSTYNNPELAAKVKASIELEVGKANVVDADPVMAGEDFGLYGRTAEAVPITLFWLGAVEPAKYEASLDSGVSLPSLHSSQFAPDYPLAISTGVRAMTRSAIDLFNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ07</accession>
    <name>B1KQ07_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molybdenum cofactor synthesis domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327437.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4871"/>
    <dbReference type="EnsemblBacteria" id="ACA89120">
        <property type="protein sequence ID" value="ACA89120"/>
        <property type="gene ID" value="Swoo_4871"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4871"/>
    <dbReference type="eggNOG" id="COG0521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077358_1_0_6"/>
    <dbReference type="OMA" id="EYLTSEW"/>
    <dbReference type="OrthoDB" id="1877633at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="3">
        <location>
            <begin position="7"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA89120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="177" mass="19285" checksum="1AD228C7C7E181F9" modified="2008-04-29" version="1">MTKAKIGIVTVSDRASAGVYEDLSGKAIIDVLNEYLTSEWEPVYEVIPDEQDVIEATLMKMADEQNCSLIVTTGGTGPAKRDVTPEATEAVCDRMMPGFGELMRAESLKFVPTAILSRQTAGLRGDSLIVNLPGKPKSIRECLDAVFPAIPYCIDLMDGPFLECDESVIKPFRPKAK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-07-22" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ45</accession>
    <name>MNMG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mnmG</name>
        <name evidence="1" type="synonym">gidA</name>
        <name type="ordered locus">Swoo_4909</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MnmG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327474.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ45"/>
    <dbReference type="SMR" id="B1KQ45"/>
    <dbReference type="STRING" id="392500.Swoo_4909"/>
    <dbReference type="EnsemblBacteria" id="ACA89158">
        <property type="protein sequence ID" value="ACA89158"/>
        <property type="gene ID" value="Swoo_4909"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4909"/>
    <dbReference type="eggNOG" id="COG0445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007831_2_2_6"/>
    <dbReference type="OMA" id="FRPGYAI"/>
    <dbReference type="OrthoDB" id="146811at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000345332" description="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG">
        <location>
            <begin position="1"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <sequence length="630" mass="69639" checksum="E8D9F95D9339154A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQA2</accession>
    <name>B1KQA2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323106.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0459"/>
    <dbReference type="EnsemblBacteria" id="ACA84757">
        <property type="protein sequence ID" value="ACA84757"/>
        <property type="gene ID" value="Swoo_0459"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0459"/>
    <dbReference type="eggNOG" id="COG2013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789328_0_0_6"/>
    <dbReference type="OMA" id="ATMDTNM"/>
    <dbReference type="OrthoDB" id="1063432at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="349" mass="38289" checksum="86AA0E7828C1696B" modified="2008-04-29" version="1">MNQTYNITLTGELIGEIERSDAIAVFAKLFKLPLDKAHDFFHKAPLVVKKSVDGDTANKIQQILEKSGLHCEINPVEVVETEQSTQVGVMNESAVEAQDEQSAQEREEMLDSESQTTTDPEQPSASFKGLKFEMAGQPDYGFVTVHVPAGEMLKVEASAMATMDTNMQMKTKMRGGLGRMVTGENIFVNEFTAANMEGEVGIAPGAPGDLCHQYLDNETIYLQNSAFVACSSGIEVESKWQGLVKGFFSGESLFLIRAQGKGDLWFNSYGAIIEIDVNDDYVVDTGNIVGFTDGLEYQITKVGGYKSFFFSGEGLVCRFSGKGKVWIQTRSSAAFVGWAHWFRPVKSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI3</accession>
    <name>B1KQI3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324568.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1938"/>
    <dbReference type="EnsemblBacteria" id="ACA86222">
        <property type="protein sequence ID" value="ACA86222"/>
        <property type="gene ID" value="Swoo_1938"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1938"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_7_0_6"/>
    <dbReference type="OMA" id="LNRWNDS"/>
    <dbReference type="OrthoDB" id="1925754at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="39"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="196" mass="21987" checksum="CAE12EA4FBA25647" modified="2008-04-29" version="1">MPLVTPLLESNEEVAQLARFFNETLGFCPNSVLTMMRRPKIAKAFIELNMAVMDNQGRVTSLLKRLIAYVSSNVTGCRYCQAHTIRAAERYGAEQAQLDNIWEYKTHPAFTDAERAALDFSVAASTVPNGVDEELNQRLHQYWEEDEIVEILGVISLFGYLNRWNDSMATTLEEGAIASGESLLALKGWEVGKHTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM8</accession>
    <name>B1KQM8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA polymerase III, delta prime subunit</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324613.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1983"/>
    <dbReference type="EnsemblBacteria" id="ACA86267">
        <property type="protein sequence ID" value="ACA86267"/>
        <property type="gene ID" value="Swoo_1983"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1983"/>
    <dbReference type="eggNOG" id="COG0470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006229_4_3_6"/>
    <dbReference type="OMA" id="FYQIEAD"/>
    <dbReference type="OrthoDB" id="1971388at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004622">
        <property type="entry name" value="DNA_pol_HolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00678">
        <property type="entry name" value="holB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="1 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="33857" checksum="E463A52CFBC0E462" modified="2008-04-29" version="1">MQDIPWLKPVIADFSEQLKQQHVGHAYLLGVHQGYGGEQLTLDFAKAALCHSVTDQGACGFCKGCQLVEANNHPDLYHLVADGNQIKVDQVRALCQKLTSTSQQGGRRVAVLSQCEKLNLAAANALLKTLEEPGKDTLLLLQSDTPSRLMATISSRCQRVHFHSPNIDEVKAWLSQDRELSSDVTWCLPVMGGPLELASALQDQRYEQLLQLRKDWAQSLSSGHLCANLININEKQVSDAIKVLYLILRQKLVKQTQLDALLRVQVSELAAKVMDTYHRLSVMPNVNYLALFQGFILEYRKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR5</accession>
    <name>B1KQR5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Na(+)-translocating NADH-quinone reductase subunit C</fullName>
            <shortName evidence="11 12">Na(+)-NQR subunit C</shortName>
            <shortName evidence="11 12">Na(+)-translocating NQR subunit C</shortName>
            <ecNumber evidence="11 12">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">NQR complex subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">NQR-1 subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nqrC</name>
        <name evidence="14" type="ordered locus">Swoo_3403</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the NqrC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="11 12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326006.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3403"/>
    <dbReference type="EnsemblBacteria" id="ACA87671">
        <property type="protein sequence ID" value="ACA87671"/>
        <property type="gene ID" value="Swoo_3403"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3403"/>
    <dbReference type="eggNOG" id="COG2869">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077882_0_1_6"/>
    <dbReference type="OMA" id="MITGTAE"/>
    <dbReference type="OrthoDB" id="730368at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00427">
        <property type="entry name" value="NqrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010204">
        <property type="entry name" value="NqrC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37838">
        <property type="entry name" value="PTHR37838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009437">
        <property type="entry name" value="NQR-1_subunit_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01938">
        <property type="entry name" value="nqrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0288">FMN</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 12" id="KW-0915">Sodium</keyword>
    <keyword evidence="10 11 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 12" id="KW-0813">Transport</keyword>
    <keyword evidence="11 12 14" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="13">
        <location>
            <begin position="144"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="11">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="28689" checksum="1EEB1EE234CE162F" modified="2008-04-29" version="1" precursor="true">MAFKKDTVVGTMVFTFILCLLCSFMITGTAELLKERKLAKKRDELQRYVLMAADIDMSGDRDFREIFAKSVTPMLVELDTGKVTTDGNLMDFDDRMAAINPETSIKPKKDTARIKSRANQVRAFKVVDDQGELLSMVMPVYGKGLWSMIYGFVAVKSDLNTIENVVFYEHGETPGIGDFLNDPEWTDKFRNKQLYDDKGKVAIKVVKGGAKEGDVHGIDAISGATMTGRGVQRSIQFWFGNEGFETFFNKLKASEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT4</accession>
    <name>B1KQT4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Purine nucleoside phosphorylase DeoD-type</fullName>
            <shortName evidence="1">PNP</shortName>
            <ecNumber evidence="1">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">deoD</name>
        <name evidence="3" type="ordered locus">Swoo_3422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase</text>
            <dbReference type="Rhea" id="RHEA:36431"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:142361"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer; trimer of homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326025.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3422"/>
    <dbReference type="EnsemblBacteria" id="ACA87690">
        <property type="protein sequence ID" value="ACA87690"/>
        <property type="gene ID" value="Swoo_3422"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3422"/>
    <dbReference type="eggNOG" id="COG0813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068457_2_0_6"/>
    <dbReference type="OMA" id="MYYDPDE"/>
    <dbReference type="OrthoDB" id="1028277at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042278">
        <property type="term" value="P:purine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09006">
        <property type="entry name" value="PNP_EcPNPI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01627">
        <property type="entry name" value="Pur_nucleosid_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004402">
        <property type="entry name" value="DeoD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF2">
        <property type="entry name" value="PTHR43691:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00107">
        <property type="entry name" value="deoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="16"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="1">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="1">
        <location>
            <begin position="179"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="1">
        <location>
            <begin position="203"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="234" mass="25431" checksum="C5D5C579AF2E4B99" modified="2008-04-29" version="1">MTAHINAQAGDFAETIIMPGDPLRAKYIAETYLTDAVEVTNVRNMLGYTGFYKGTRISVMGHGMGIPSMVLYAHELINDFGVKRIIRVGSLGATQKDVKLHDVILAQAAGTDSPTNAKRSSGYQMATSATFSLLHKAYTAAQDKQISVKVGNIFSGDMYYDPDEDMIPALERFGVLGVDMEVAGLYGLAHQQHIESLAILTVSDHCITGEETSAEERQLSFNQMIELALETACC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU2</accession>
    <name>B1KQU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326033.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87698">
        <property type="protein sequence ID" value="ACA87698"/>
        <property type="gene ID" value="Swoo_3430"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3430"/>
    <dbReference type="eggNOG" id="ENOG5033H4C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_939735_0_0_6"/>
    <dbReference type="OMA" id="PYALNGF"/>
    <dbReference type="OrthoDB" id="1222559at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767304" evidence="1">
        <location>
            <begin position="22"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="253" mass="27731" checksum="7FA706DDF69A47B8" modified="2008-04-29" version="1" precursor="true">MKNSTISLAILLGLTSMSAVAAQDNAFQHQASLSYSTNSEEVSDGAWNANYRYYIAPVDQSNSPYALNGFLAQTTNLGASYSKLDVGIYDSDAYRVDGTYVFASKWFVSASYGRVEFLNTDYDAYRGEVGYYFNESSSISAFYADGDNNAVEVYGLNLRSFVALESTAGVDLTANWTHTDSDDAFNLGADWYVNNSWSVGAGYHNNDANDDFSLRTAYWLRISDNFSANFNLSKFLDSDADGVGMSVGVVGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQV4</accession>
    <name>B1KQV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fmu (Sun) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326045.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3442"/>
    <dbReference type="EnsemblBacteria" id="ACA87710">
        <property type="protein sequence ID" value="ACA87710"/>
        <property type="gene ID" value="Swoo_3442"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3442"/>
    <dbReference type="eggNOG" id="COG0144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_0_2_6"/>
    <dbReference type="OMA" id="TVWPFEA"/>
    <dbReference type="OrthoDB" id="1064993at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="6">
        <location>
            <begin position="184"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="460" mass="52044" checksum="D170CE54D881D8EE" modified="2008-04-29" version="1">MVDALNTSQTRSTEPSADALSFDNLQADTPAQKRALSYANTIYQLFHQVMDKQQPADRVVGEYFRVNKKHGSKDRRVIRESLFALFRWWGWLRKFDSQSEIEQTWLIQLTINARLESHPWSEFISAWETFAGLVSINSAPEFSHISQRATWLNEQFSEHCFTTDELVPDWFWEVCPSENSEQRLALVESLSSRPPIWGRVQNIDLDDAIQSLQKLDIPAKGCEFFSDSINLGNKNINLNGLSLYKEGELEIQDLGSQVVGQLCQPRADDNWWDTCSGAGGKSLQIRSLMLQQSQEAQGSIIASDIRRKPLEELAKRAKRAGFKKITTSPWKSDELPVPHAHFDGVLVDAPCSCTGTWRRNPDMRWIDTIDTVLDKPSLQLDILTRSSKAVKAGATLVYATCSLSPLENEEVVKAFLAQHSDFSLEITTHPFTGAKDTMHTVVPYQADTDGMFVARMLKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQW3</accession>
    <name>B1KQW3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate regulon sensor protein PhoR</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3451</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326054.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3451"/>
    <dbReference type="EnsemblBacteria" id="ACA87719">
        <property type="protein sequence ID" value="ACA87719"/>
        <property type="gene ID" value="Swoo_3451"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3451"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_2_6"/>
    <dbReference type="OMA" id="TRFWRGS"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021766">
        <property type="entry name" value="PhoR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014310">
        <property type="entry name" value="Sig_transdc_His_kinase_PhoR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11808">
        <property type="entry name" value="PhoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02966">
        <property type="entry name" value="phoR_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="212"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="431" mass="49041" checksum="90EAF1ABF5DBF2F2" modified="2008-04-29" version="1">MFDSYSGYRLLSRLITYLVLCFILGLLIGEIVWVLLLGTVVLLFWHYRQLSRLNFWLWRDRRLTPPNGRGSWEGVFNGIYRLQGKNRKRVSQLAFLLGRFRQGAEALPDAAVVLDAEHNIVWCNKLAQVLLGLVWPLDSGQRIDNLLRHPDFSNYLKKGSYQEPLELASPHSDSRILEIRIMGYGTGQFLLIARDITRVRQLESMRKDFVANVSHELKTPLTVLQGYLEMMQEMAEPGSPNIKAMDQMQQQTNRMRSMVEQLLVLSRIEDSTEINLEMTINMSHMMDVLREEAMALSQDEHELEFHCEASDLYGNELELRSACSNLISNAIRYTQPGGKVSVRWKSVASGAVFSVTDTGDGIAPQHIGRLTERFYRVDSARTRQKGGTGLGLAITKHALSHHQSELMISSELGKGSTFSFLIPTSLMDYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR41</accession>
    <name>B1KR41_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323206.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0562"/>
    <dbReference type="EnsemblBacteria" id="ACA84858">
        <property type="protein sequence ID" value="ACA84858"/>
        <property type="gene ID" value="Swoo_0562"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0562"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_2_6"/>
    <dbReference type="OMA" id="WTFQAGE"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="312" mass="33973" checksum="E0DE4A4BEDCC4B15" modified="2008-04-29" version="1">MSFPSLVTLDIGGTKINAGRYVNGVIEDSRSFKFCANASLSEIECFIINCIDGFLIQSTTAICIGVPCIVDTQLGVVYDAVNIPAWKEFDLKSALQRRYHLDVYINNDVNCFTAGEHRFGAGQGYDDIIGLCLGTGVGAGYIINNELYQGHNCSAGEIGEVCYLTSTIDEYCSGRFFDLHIGASGTDLAVKARSGEAYAIEAYSQFGRHLAHAISHLLLILDPQVIVIGGSVAHSFDLFKEELWLGLADFPYNKVIENLKIIPSSNRDTALLGAAQLYLNQCKQNKKTEVTAQIVNSREVSAESYLTSPQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR43</accession>
    <name>B1KR43_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="B1KR43"/>
    <dbReference type="STRING" id="392500.Swoo_0564"/>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84860">
        <property type="protein sequence ID" value="ACA84860"/>
        <property type="gene ID" value="Swoo_0564"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0564"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052178_1_0_6"/>
    <dbReference type="OMA" id="HMVHNCV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767581" evidence="2">
        <location>
            <begin position="23"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="25"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="424" mass="46223" checksum="382762EF749A4692" modified="2008-04-29" version="1" precursor="true">MKLTTLTCALSLALASISYAQASDKTIYLTFDDGPMNATPALIDTLDNAGIKATFYINAWHLDGIADENEDQALSALIQTLKSGHVVANHSYDHMVHNCVEEFGPTSGAECNATGDHQINSYQDPVYDASMFSENLTVLESYIPNIQSYPNYKAASLARLPYTNGWRSSGELKGDGLCATSDDFKPWEPGYVCDAENPSNSSKAGVEVSNILADKGYLIHGWDLDWAPENWGIPYPANSLTEAEAFLGYVDAALNACAPVTINPVNSKTQTFPCGDALHADKVIILTHDFLFEDAKRGQGATLNLPKLAKFIELALAAGYQFDTMDNYAPQWLSETSYQEGDYVTYNNAVFKAVSAHTSQNNWAPTASSNLWLKSTPSSVWTENVSYQAGESVTYMGQTYTVIADHVSQTLWAPDVSDTLFLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR99</accession>
    <name>B1KR99_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2022</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324652.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2022"/>
    <dbReference type="EnsemblBacteria" id="ACA86306">
        <property type="protein sequence ID" value="ACA86306"/>
        <property type="gene ID" value="Swoo_2022"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2022"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_10_6"/>
    <dbReference type="OMA" id="NWFGGVY"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="288"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="42714" checksum="DB6B1A287B101CA9" modified="2008-04-29" version="1" precursor="true">MMIIRLVIAQLLNTKIRTLLTFFSILVTFLLFGLLFSISSYFNGTVNIAGAQRVISTHKTSLIQMLPVDYGNKIAALDGVRSVTHATWFGGQYISPKNFFPKFAVVPQDFLTIYPEMLLEPDALNLWLSTRIGVVAGRTIADKYGWKIGQKINIEADIWPKKNGGSTWEFELVGIYDGKDASVDTSRFLLRYDYFDAARSHSKGQVGYYIIESEDASQNDKVSSSVDRLFSNSVAETKTSSEAEYTKATMKQIGDIGGAIKVVLFAVIFTIILVTNNAITQSVRERTQVIAVLKTLGYTDFNIFCLVLVETLILVFLGALAGLLLAQGVLSSIEKPLESLFNSTIVLPSEVWLYSIVTALIIVVVSGLPPARIALKQKIAKAIIGDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRF8</accession>
    <name>B1KRF8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Histidine biosynthesis bifunctional protein HisIE</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="13">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <shortName evidence="13">PRA-CH</shortName>
                <ecNumber evidence="13">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="13">Phosphoribosyl-ATP pyrophosphatase</fullName>
                <shortName evidence="13">PRA-PH</shortName>
                <ecNumber evidence="13">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="primary">hisI</name>
        <name evidence="13" type="synonym">hisIE</name>
        <name evidence="15" type="ordered locus">Swoo_2081</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 13">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">In the C-terminal section; belongs to the PRA-PH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">In the N-terminal section; belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="13"/>
    <dbReference type="EC" id="3.6.1.31" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324710.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2081"/>
    <dbReference type="EnsemblBacteria" id="ACA86365">
        <property type="protein sequence ID" value="ACA86365"/>
        <property type="gene ID" value="Swoo_2081"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2081"/>
    <dbReference type="eggNOG" id="COG0139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_3_1_6"/>
    <dbReference type="OMA" id="ERSCFHQ"/>
    <dbReference type="OrthoDB" id="1842189at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01019">
        <property type="entry name" value="HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023019">
        <property type="entry name" value="His_synth_HisIE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRA-CH" evidence="14">
        <location>
            <begin position="38"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-AMP cyclohydrolase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-ATP pyrophosphohydrolase" evidence="13">
        <location>
            <begin position="119"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA86365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="23070" checksum="E19A26CA476860D3" modified="2008-04-29" version="1">MTDSVKDKSALSNSLDWDKQDGLIPAIVQNHLTGKVLMLGYMDKAALDKTLETGSVTFFSRSKQALWTKGETSGHTLELVAIDKDCDNDSLLMQVLPNGPTCHLQTESCWPDGNAHTFLDNLANLIADRKGDDPKSSYTAHLFESGTKRIAQKVGEEGLEAALAAATHDKPELIDEASDLIYHLLVLLEDQELSLADITDNLRKRHLKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRM6</accession>
    <name>B1KRM6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperone protein TorD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">torD</name>
        <name evidence="4" type="ordered locus">Swoo_3527</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TorD/DmsD family. TorD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3527"/>
    <dbReference type="EnsemblBacteria" id="ACA87791">
        <property type="protein sequence ID" value="ACA87791"/>
        <property type="gene ID" value="Swoo_3527"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3527"/>
    <dbReference type="eggNOG" id="COG3381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077650_4_0_6"/>
    <dbReference type="OMA" id="PYASMYI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01150">
        <property type="entry name" value="TorD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023069">
        <property type="entry name" value="Chaperone_TorD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="223" mass="24502" checksum="F7575BC946240411" modified="2008-04-29" version="1">MNGSNMSASEMNASEMNSVAVVNQARAMVYRLLSSLFAKEVDHQLLHELTGEQAQAFLAQLASEPAFKQDIDTLISVLNTLKTDKALLELAADYCGLFLVGTKHSASPYASLYLNEAGSETPLFGEQHQQMVQFLKQSQLQVQTSFPEPADHIAVILAYAEHICLNSGDAEQLKFIESYLNTWLGNFAAKVTQCDTGTFYSALARLTQSWVTSDLEGLTQTTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRP2</accession>
    <name>B1KRP2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326140.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3543"/>
    <dbReference type="EnsemblBacteria" id="ACA87807">
        <property type="protein sequence ID" value="ACA87807"/>
        <property type="gene ID" value="Swoo_3543"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3543"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_911194_0_0_6"/>
    <dbReference type="OMA" id="NRRFWYS"/>
    <dbReference type="OrthoDB" id="891360at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="32"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="313" mass="35434" checksum="55CAE22DA756DFFE" modified="2008-04-29" version="1">MDLEQTSFYIPYLEGQLHLRQVKLANADMHKPPIFMLHGAMSNGKVFYSESGRGLACFLAEAGFVVYVLDTQGRGLSTPKIQRGFKEGQGEVIREQLPLVHHYIMGLHSQVSSIHWCAHSWGGVLMASAISRFPLFQESVASLLTFGTKRTIKVSSVKKYMMVNIGWNKLAKVIAWGHGYLAADRWGMGMDNESRRSLSQCVDWVRGDWIDHDDGFDYAQAAQVVASKERWPKSWFIAGLGDEVLGNPADVQRMIQECQFSDVEYTLLAKSQGHKHDYGHAEMLIHKDAVDDHFIQVRDWYKNIELSEAKVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ1</accession>
    <name>B1KCZ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322669.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0019"/>
    <dbReference type="EnsemblBacteria" id="ACA84320">
        <property type="protein sequence ID" value="ACA84320"/>
        <property type="gene ID" value="Swoo_0019"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0019"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117112_3_0_6"/>
    <dbReference type="OMA" id="HEMDIYP"/>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039840">
        <property type="entry name" value="NAA80"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13538">
        <property type="entry name" value="PTHR13538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="17984" checksum="1B7B14F640C7E08A" modified="2008-04-29" version="1">MEINLLKDKPDLIPKIAKWYSDEWGYIDDGSGKESRSTTALEIKLAEYLNSDTIPLMLVATKNQSLIAAAQLRFQENSRYPSDSHWLGGVYVCESHRGNGAGQALIEAIVTKAKQLNVQQLYLQTEDLSGGLYKKMGWKAVEEVKYCGIDLLIMQRDLIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD19</accession>
    <name>B1KD19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hexapeptide-repeat containing-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326187.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87854">
        <property type="protein sequence ID" value="ACA87854"/>
        <property type="gene ID" value="Swoo_3590"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3590"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_3_0_6"/>
    <dbReference type="OMA" id="NQGCTFM"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="4">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="20921" checksum="DEFA35E3E728CB4A" modified="2008-04-29" version="1">MSEFEKMLAGKDFDGGADSINHIRQNASNLLQAINQNTDDSQRSELFQQLMGNISASSIVRSPFYCEFGKTISIGEKTFINMNVTMLDGAKITIGNNVLIGPNTQLYSASHDLNYLKRRNWETICAPITIEDDVWIGGNVVINKGVTIGTRSVIAANSVVNTDVPPDSLYGGTPAKLIRMIDENGQVHKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD92</accession>
    <name>B1KD92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-keto-3-deoxy-galactonokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326260.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3665"/>
    <dbReference type="EnsemblBacteria" id="ACA87927">
        <property type="protein sequence ID" value="ACA87927"/>
        <property type="gene ID" value="Swoo_3665"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3665"/>
    <dbReference type="eggNOG" id="COG3734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058005_2_0_6"/>
    <dbReference type="OMA" id="RNGWIEM"/>
    <dbReference type="OrthoDB" id="1530579at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008671">
        <property type="term" value="F:2-dehydro-3-deoxygalactonokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034194">
        <property type="term" value="P:D-galactonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007729">
        <property type="entry name" value="DGOK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042257">
        <property type="entry name" value="DGOK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042258">
        <property type="entry name" value="DGOK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05035">
        <property type="entry name" value="DGOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="315" mass="34748" checksum="8F5625A119E711F1" modified="2008-04-29" version="1">MRRQADVIVVDWGASFLRAYLCFDNGGELEVIEQVLGPGAAKVSQQFEAALNSVIGHWSAQYGALPVLMSGHIGSSLGWHETPYISCPVPPLEVTKELFEFESNGHSIFVVPGVSCEEPDGHADVMRGEETHVLGWLTMDDSHRRGKHLLCLPGTHTKWVLVEEGEIKVFKTAITGELFDLLCHHSVLIQQQQSEIDIRAFEQGAKLTLESELGQFVHGLFSVRTLQVQGKLDADHAKSYLSGLLIGSDVRAALMAPQWRIDELASISLIGSHPLCELFSQTLKMKGITVHSTQEKETCLRGFSAIYRKVFKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDB3</accession>
    <name>B1KDB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323262.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0618"/>
    <dbReference type="EnsemblBacteria" id="ACA84914">
        <property type="protein sequence ID" value="ACA84914"/>
        <property type="gene ID" value="Swoo_0618"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0618"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_426342_0_0_6"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="254"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="395"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="642" mass="73126" checksum="D88CF6E95D8E0E56" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDH0</accession>
    <name>B1KDH0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0675"/>
    <dbReference type="EnsemblBacteria" id="ACA84971">
        <property type="protein sequence ID" value="ACA84971"/>
        <property type="gene ID" value="Swoo_0675"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0675"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120448_0_0_6"/>
    <dbReference type="OMA" id="LWEHAKT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="150" mass="16377" checksum="98DDBABB998A3C99" modified="2008-04-29" version="1">MIIRKLEDRDLAQVSSVCLNSFMKSVAPSLSDVGISTFQKISSVDSFTARLKENIDILVCEENEKIQGIIELKDGRHISMLFVSPEHQKQGVGRSLLLSIMSFTTSDTITVSASLTSVNAYLSFGFVLSGGISEASGLRFQPMKLELNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDH3</accession>
    <name>B1KDH3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0678"/>
    <dbReference type="EnsemblBacteria" id="ACA84974">
        <property type="protein sequence ID" value="ACA84974"/>
        <property type="gene ID" value="Swoo_0678"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0678"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_6"/>
    <dbReference type="OMA" id="CTHIADI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="20"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="334"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="583"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="366"/>
            <end position="373"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="657" mass="73519" checksum="E416E127F63201D5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM5</accession>
    <name>B1KDM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BNR repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324767.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2138"/>
    <dbReference type="EnsemblBacteria" id="ACA86422">
        <property type="protein sequence ID" value="ACA86422"/>
        <property type="gene ID" value="Swoo_2138"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2138"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063224_1_0_6"/>
    <dbReference type="OMA" id="GHDATII"/>
    <dbReference type="OrthoDB" id="1293876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028203">
        <property type="entry name" value="PSII_CF48-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14870">
        <property type="entry name" value="PSII_BNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766976" evidence="1">
        <location>
            <begin position="26"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="2">
        <location>
            <begin position="70"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="342" mass="37604" checksum="0C6C28674DD3C419" modified="2008-04-29" version="1" precursor="true">MLSSMLRFISIFLFAVTLSPSIAIASSDSLSLSNQIQPLAIKSIILDIAVKDETMVAVGERGHIFIFDEKSTPKWRQVPSPTSSHLTKVFFTTPSLGWAVGHDATIIHTQDAGLTWQVQMSSPEIEKPLMDVLFFDTDNGVAIGAYGLFYRTDNGGKNWTPEYHEELLFEEDIAYLAELKAEDEALYLSERSTLLPHFNRIIATNDGCLIMVGELGLVSVSDDSGVNWQKLDFVYEGSLFNVIESDNGFYVMGLRGNIFQTGLDLNRWDQVMLPTKSTINGAILAKDGGLRVVGNAGVILDITANGKGELVTQRQGENLVSIARDPQGHIWVAGTKGLFELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU0</accession>
    <name>B1KDU0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326275.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87942">
        <property type="protein sequence ID" value="ACA87942"/>
        <property type="gene ID" value="Swoo_3680"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3680"/>
    <dbReference type="eggNOG" id="ENOG5031KF6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2371215_0_0_6"/>
    <dbReference type="OMA" id="LEYQSAY"/>
    <dbReference type="OrthoDB" id="2072314at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045508">
        <property type="entry name" value="DUF6482"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20090">
        <property type="entry name" value="DUF6482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11556" checksum="E2C414887B7B1CB3" modified="2008-04-29" version="1">MDIHFQESSQVQETSKIQQFSPKIIGVADSTQYLVGAIDCKNNFVELNEEKRIRCFNSLAQAKDLLRSHQYKTVELEYQSAYDEMCGLPSCDNYKELIQL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV1</accession>
    <name>PTH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name type="ordered locus">Swoo_3693</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326285.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDV1"/>
    <dbReference type="SMR" id="B1KDV1"/>
    <dbReference type="STRING" id="392500.Swoo_3693"/>
    <dbReference type="EnsemblBacteria" id="ACA87953">
        <property type="protein sequence ID" value="ACA87953"/>
        <property type="gene ID" value="Swoo_3693"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3693"/>
    <dbReference type="eggNOG" id="COG0193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062456_3_1_6"/>
    <dbReference type="OMA" id="HVLSKFH"/>
    <dbReference type="OrthoDB" id="1676462at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000092985" description="Peptidyl-tRNA hydrolase">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <sequence length="194" mass="20953" checksum="19B37962BB57A5E4" modified="2008-04-29" version="1">MSNIKLIVGLANPGEKYAQTRHNAGAWYVQELARVCGATLVADSKYFGLTARVTLHGKDVRLLIPSTFMNLSGKSVGAMANFFRIEADEILVAHDELDMEPGVAKFKLGGGHGGHNGLKDIIASLANNKGFYRLRIGIGHPGDKSQVSNYVLGKAPGTEQAAIEDVIDEAVRSTEVLFNQDMAKAMNRLHAYKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV4</accession>
    <name>MIAB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber evidence="1">2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">miaB</name>
        <name type="ordered locus">Swoo_3696</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326288.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDV4"/>
    <dbReference type="SMR" id="B1KDV4"/>
    <dbReference type="STRING" id="392500.Swoo_3696"/>
    <dbReference type="EnsemblBacteria" id="ACA87956">
        <property type="protein sequence ID" value="ACA87956"/>
        <property type="gene ID" value="Swoo_3696"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3696"/>
    <dbReference type="eggNOG" id="COG0621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018697_2_0_6"/>
    <dbReference type="OMA" id="CEHFHIP"/>
    <dbReference type="OrthoDB" id="397139at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000374549" description="tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase">
        <location>
            <begin position="1"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="MTTase N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="143"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="1">
        <location>
            <begin position="378"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <sequence length="474" mass="53829" checksum="5AFB1D5D4A7E745D" modified="2008-04-29" version="1">MSKKLHIKTWGCQMNEYDSSKMADLMDEYKGYTLTEEAEEADVLLLNTCSIREKAQEKVFHQLGRWKKLKDKNPNLIIGVGGCVASQEGKVIKDRAQCVDLIFGPQTLHRLPEMIDQIEAGGKAVIDVSFPEIEKFDRLPEPRADGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPLDDVILEIAQLAEQGVREVNLLGQNVNAYRGATHDDEICTFAELLRYVAAIDGIDRLRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDRILTQMKRGHMAIEYKSIIRRLRKARPDIQVSSDFIIGFPGESKQDFEDTMKLIEDVQFDHSFSFIYSARPGTPASDLPDDVTLDEKKERLAILQDRITQQAMRYSRQMLGTVQRILVEGPSVKNPMELRGRTETSRVVNFEADPKHIGSFVDVEIVDVYTNSLRGNFIRGEDEMDLRRSLRPSDILAKHKKDDELGVTQYIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE27</accession>
    <name>B1KE27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323360.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0718"/>
    <dbReference type="EnsemblBacteria" id="ACA85013">
        <property type="protein sequence ID" value="ACA85013"/>
        <property type="gene ID" value="Swoo_0718"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0718"/>
    <dbReference type="eggNOG" id="COG3025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040400_0_2_6"/>
    <dbReference type="OMA" id="WDMGLRV"/>
    <dbReference type="OrthoDB" id="1878295at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050355">
        <property type="term" value="F:triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007899">
        <property type="entry name" value="CHAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039013">
        <property type="entry name" value="YgiF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39569">
        <property type="entry name" value="PTHR39569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51708">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="2"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="CHAD" evidence="2">
        <location>
            <begin position="223"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="500" mass="56711" checksum="7D454D66B3D44831" modified="2008-04-29" version="1">MDAEIELKLFFQLEQQEALIQLLDNLPHSEPQWCRNLTNAYFETPDLQLRRWDMGLRVRGCDGALEQTIKTAGSVIGGIHSRPEFNVDIDQNFPILSLFPEKIWPDKSIISSVQSKLTCLFHTDFTRRTWHIYVDNSLIEVALDVGQIAVDVAGEQRVEPICELEFELMAGEAQALIKLGRQVAQSLPVRLGKASKAQRGYRLAAQASPLSLEVLEFITLKPEQDLKQTLIDLLSTGLERWQLLEAMILESDSALDKQLPTLCYRLRACIRLLRCTLAQFELLSAELTSKFDCIEAHLEFVESSLSCVEILKERSLLISKLPQSKTLTELVSMQLLLLSIPQRVGKMLDDLCYGGLQLSLVELLFAFKSGQQTLDSESSLQAFADKMQEASWLRIVNLMPSEMDLSSTDYQDFARALDESVFVGVAYGGLYSAKSRDLFRLPWQDLVLGIRTLAAYRKLAELSQENGIDISPWLTNKEDSLLFAMEHSRRTALKNEPYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEZ5</accession>
    <name>B1KEZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85146">
        <property type="protein sequence ID" value="ACA85146"/>
        <property type="gene ID" value="Swoo_0851"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0851"/>
    <dbReference type="eggNOG" id="ENOG5030AFJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_798992_0_0_6"/>
    <dbReference type="OMA" id="NEMAMYI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="347" mass="40166" checksum="D90697B3A9CD1AD9" modified="2008-04-29" version="1">MEEGSNTYAKTVYRGSLWEEQSQYHPHTFSGMTHLPHCDYRNVNPSTYTEDMYDVIHSSEDDLNNEHCLESFEFNSRVIRIVTFSRSFAIPLLFSLGGFCLCLFGVMMFAARLVRLYFSDNSIELTMEILQFPLLAILGLFLFCIQFMPDPIVKIFFGDVVPHIQVSRQTGLVTIWRYIPILGIKRKTIIKPFSEFIPYLHHLVTPTGTGAGWNVFLAHKDSRRISFGAIGMANPKSRGDALAFWDFLQRYMDVEQPLPDSPVFETVRHLDPTTKAYDEMVGRPAKYWKRMTKAQIDRRSNEMAMYIERLANGEDLSPFEFDYEAMLTPHEQKQRKRAKKNSHAEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF95</accession>
    <name>B1KF95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2357</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324978.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2357"/>
    <dbReference type="EnsemblBacteria" id="ACA86636">
        <property type="protein sequence ID" value="ACA86636"/>
        <property type="gene ID" value="Swoo_2357"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2357"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1401432_0_0_6"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="42"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="137"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="22593" checksum="64C53C385E07A5D9" modified="2008-04-29" version="1">MNKVNGPTCVINSPEKITQMHELQKRPDDYFFCWPSISEHLYKYCRFKLMLNHWDAEDVVADTMLKAYDNFKTANPSSNIQGWLTLLARNIHFDQIRRFKSIKNNVEDVLNNNSNLIDEPFNNKAEMNSIKVVKEVINRLNDKNKTITFDFFFNDKNYKEISHEYGIPAHQVRQRIHRSREKIKLTLNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFB3</accession>
    <name>B1KFB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324996.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2375"/>
    <dbReference type="EnsemblBacteria" id="ACA86654">
        <property type="protein sequence ID" value="ACA86654"/>
        <property type="gene ID" value="Swoo_2375"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2375"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_133_5_6"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="271"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="207"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="504" mass="57522" checksum="26E24D63BB16A296" modified="2008-04-29" version="1" precursor="true">MQLLKGIYLFTFKNKVVLASSITLLSFIVIGAFTTYSLLKLKQEFETLFTISELRTRVIFQAHNSVLNMESELIKLVIADEKKQIRKSSVASIRATALLDESLQQLQLELPNNQTVNTLSRNLNEIKPFRMKIIGLAKSNRDQEALKIIDDIAPITALIGEDLNKIIIQDRKELNLLFNDYKNSEITILLIFSIIIALAVILLIVANANLQKTKMALNKLNHQLEHKVKSRTEQLERSYNEIENTLEQLKITQSQLIESEKMASLGGLVSGISHELNTPIGVCITSGSFLIDSTSIFEKRFLEGLIDETDCQEYIEVNKESMALILSNLNKCSELIQYFKKISTQQTSEEPELFYIKQYIDETVLYTRTHFKETHSNIKVNCSDTLQVKLVIGVLNEIIMNLVMNSLQHGYDKILDEPVEVNIEVTKSDNRVKIRYWDSGKGINKADIDKAFEPFYTTKRGEGRNGLGLTIVYNLVRHSLNGKIECLYNENNQMQFVIEFPDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFD8</accession>
    <name>B1KFD8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3855"/>
    <dbReference type="EnsemblBacteria" id="ACA88113">
        <property type="protein sequence ID" value="ACA88113"/>
        <property type="gene ID" value="Swoo_3855"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3855"/>
    <dbReference type="HOGENOM" id="CLU_3332953_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="38" mass="4204" checksum="C15E784C82A7C283" modified="2008-04-29" version="1">MPKRDLIYFVGIAFKKLMANNAIFASKVYVITPSSVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE0</accession>
    <name>B1KFE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326445.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3857"/>
    <dbReference type="EnsemblBacteria" id="ACA88115">
        <property type="protein sequence ID" value="ACA88115"/>
        <property type="gene ID" value="Swoo_3857"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3857"/>
    <dbReference type="eggNOG" id="ENOG5033800">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1546304_0_0_6"/>
    <dbReference type="OMA" id="IGYKQDS"/>
    <dbReference type="OrthoDB" id="1436999at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767309" evidence="1">
        <location>
            <begin position="20"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19256" checksum="0DC150FFC3DC12DF" modified="2008-04-29" version="1" precursor="true">MRAIVLGLLALFICGCSTTYPNQSVTGTQFPKASGETLEGEPLTLPDDLNGQPALLLIGYKQDSQFDIDRWLIGLDMTQTRIDVYEVPTIQGLFPRMFSTMINNGMRAGIPKPLWKGVVTVYQDGDKVQSYTGNEDPNNARVVLLDESGTVLYFYDDGFSVEALNKLRAIVAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFF1</accession>
    <name>B1KFF1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RHH_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326456.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3868"/>
    <dbReference type="EnsemblBacteria" id="ACA88126">
        <property type="protein sequence ID" value="ACA88126"/>
        <property type="gene ID" value="Swoo_3868"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3868"/>
    <dbReference type="eggNOG" id="COG4321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155738_2_1_6"/>
    <dbReference type="OMA" id="RVCCARY"/>
    <dbReference type="OrthoDB" id="1837705at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3990.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027373">
        <property type="entry name" value="RHH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038268">
        <property type="entry name" value="RHH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13467">
        <property type="entry name" value="RHH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_4" evidence="1">
        <location>
            <begin position="16"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="91" mass="10475" checksum="FAAF5BC0E79055E0" modified="2008-04-29" version="1">MSNLFFDNPTSHYLPIQKSIRIQGHVTSISLEKLFWDLLDQIAESQGMKRNQFIASLYIEALDHHGDVKNFTSLLRSACVQHILSDKSEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFJ7</accession>
    <name>B1KFJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326502.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3914"/>
    <dbReference type="EnsemblBacteria" id="ACA88172">
        <property type="protein sequence ID" value="ACA88172"/>
        <property type="gene ID" value="Swoo_3914"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3914"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_14_4_6"/>
    <dbReference type="OMA" id="IAVWPWY"/>
    <dbReference type="OrthoDB" id="1560019at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="45"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="135"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="285" mass="31973" checksum="1D2243F5A98AAE13" modified="2008-04-29" version="1">MTNQYIPAKVWTMDNENGGEWASINRPDSGPRHEKVLAKGTQPLQLHSLATPNGQKVTIMLEELLAKGVTEAEYDAYLISIGDGDQFSSGFVDINPNSKIPALLDTSVDSPIRVFESGNILLYLAEKFGHFLPTDLVAKTEVMNWLFWLQGSAPYLGGGFGHFYAYAPEKFEYPINRFTMEAKRQLDVLDKQLANNEFIGGSEYSIADIAIWPWYGSLVLGNLYNAAEFLDVSSYPHLVRWAKQVSERDAVKRGRIVNRSWGEEWEQLAERHSAADIDAVLAKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL4</accession>
    <name>B1KFL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326519.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88189">
        <property type="protein sequence ID" value="ACA88189"/>
        <property type="gene ID" value="Swoo_3931"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3931"/>
    <dbReference type="eggNOG" id="ENOG503352B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2025791_0_0_6"/>
    <dbReference type="OMA" id="IKLLGWQ"/>
    <dbReference type="OrthoDB" id="2015015at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12896" checksum="3547DD06E145DDC5" modified="2008-04-29" version="1">MSQVIATLLAIFFIFASSIKLLGWQKLIFETQLSFFLKYGLNRAMMFIVGLIELTGALLLILFLMTSLHEYQFLGAWLLGLTSLGALFFHFKFDKWTDAIPAGMTLLLSLLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW9</accession>
    <name>B1KFW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325018.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2398"/>
    <dbReference type="EnsemblBacteria" id="ACA86676">
        <property type="protein sequence ID" value="ACA86676"/>
        <property type="gene ID" value="Swoo_2398"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2398"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045103_1_0_6"/>
    <dbReference type="OMA" id="DEWLVIP"/>
    <dbReference type="OrthoDB" id="1819702at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="27"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="46687" checksum="7294461168AD9A2A" modified="2008-04-29" version="1">MQEQNNTTLIEKDLHEKSKVLLSEQEDHYRIFQTQMSPYSHKVMTYMNYKGIPYKRVHANQMDISWAINNVGQSIVPVLITPDDQIMQDSTPILEYLEKQYPQPAAIPNSPLLSFLMWLLEDFADEYLQRLQMHTRWGNNLNIQTASHKISRNFAYGVPKLDIKSLAPVIQARQKKNDSLLGLEGDKQRQNLDQQVLDLLCILDARLEESQFLLGNRPSMADFAFYGPLMIHLYNDPQSNHILETNAPRVCNWLFTIQELGDTRGCVGQTELGEWIDSETDLPPSLLELLKFVSQTYIPLGRATAKASVLREKHFEASVYGIKTTFGASHYKAWAFEQTQLRYRALTNDTKTKIDGILLETGILPGLLEDGVLHNGLYDGFSPPFVKDGIPDARIKHLKEKQQQKKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFX1</accession>
    <name>B1KFX1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325020.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2400"/>
    <dbReference type="EnsemblBacteria" id="ACA86678">
        <property type="protein sequence ID" value="ACA86678"/>
        <property type="gene ID" value="Swoo_2400"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2400"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_11_1_6"/>
    <dbReference type="OMA" id="EAYPMVQ"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764834" evidence="5">
        <location>
            <begin position="21"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="565"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="589" mass="65882" checksum="6CDF2FB447E4FFE0" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFZ9</accession>
    <name>B1KFZ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2428"/>
    <dbReference type="EnsemblBacteria" id="ACA86706">
        <property type="protein sequence ID" value="ACA86706"/>
        <property type="gene ID" value="Swoo_2428"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2428"/>
    <dbReference type="eggNOG" id="ENOG5030SYM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2371220_0_0_6"/>
    <dbReference type="OMA" id="SKQKVWQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="95" mass="10387" checksum="1B1886BFB2B096BF" modified="2008-04-29" version="1">MRTSHVNLSISADKLAKLIHSGELCAADFRCLDHESKQTVWQLCLLCCSKRVGCLNPCSTPCSQSTNFVTQPDSNTSIEQVDEITSSGNKITNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG00</accession>
    <name>B1KG00_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2429</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325049.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2429"/>
    <dbReference type="EnsemblBacteria" id="ACA86707">
        <property type="protein sequence ID" value="ACA86707"/>
        <property type="gene ID" value="Swoo_2429"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2429"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_42_0_6"/>
    <dbReference type="OMA" id="FNVAQFK"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="7">
        <location>
            <begin position="33"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="6">
        <location>
            <begin position="197"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="430" mass="49562" checksum="64F2D6EDDA2689EE" modified="2008-04-29" version="1">MLMPPVLPLFESSIHIHEGNTYINQYITQISINQVDDAGLLYEHATELLYEQKSNENSYKAYRSELTTFFHWCFDVAKLSPAKLTRREISRYLDYCENPPKALIGYFNVAQFKLDKASGDRMPNPAWRPFVGKKKLGKEQDYTLSENALKTKVAILSSFYSYLMSEDFCERNPAQAWMNHSRFSSKKKYQIKDEEGSMLSFTELQWSYVISTVEHLAKEQPELHQRSLFLIKLIYFCYLRISEVSARAGYTPVMEQFRQNSQTGIWSFYIPQSKGGKQRSVAISKGLLAGLVEYRRFLKLPDFPVIGENHPLFIRHRAAGRGREVGTLNANLGIRQIREEIDKIIENAAKSIENDGLFEDAYQMRKLTAHNIRHTGITHDININGRPLSHVQADAGHESIDTTSQYLHTSQIERHHSAQNKPLDHLHGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG27</accession>
    <name>B1KG27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2457"/>
    <dbReference type="EnsemblBacteria" id="ACA86734">
        <property type="protein sequence ID" value="ACA86734"/>
        <property type="gene ID" value="Swoo_2457"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2457"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_946272_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="294" mass="33655" checksum="075E1847DB51DB7C" modified="2008-04-29" version="1">MMNLRIKSSGEEVKSLQELLTVLHLSPGPIDGEFGDKTEDAVLQFQEQQGLYADGVVGTITWNALKKAAVVQLDEQNQPSVESDRLMSWQRVAADPYQDGYNRFYLREDAAKAYLRVYEKVKQAGGLLTSSGARRALNAEVNPSRSATSFHYTGRALDLFVGSGMKKTKTDPFIISSDGDRLWRVYARAEEGEQMDIEAITYDSRQRGKLVTGRFVDLTSLFKEEGFERIRARRSFFKGGSWLGAEWWHFQYEEGLEKGKSTFGNELLKVYREQTLNLTPVWQYRHYIFGDKWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL3</accession>
    <name>B1KGL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323687.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1048"/>
    <dbReference type="EnsemblBacteria" id="ACA85341">
        <property type="protein sequence ID" value="ACA85341"/>
        <property type="gene ID" value="Swoo_1048"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1048"/>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078469_2_0_6"/>
    <dbReference type="OMA" id="LCQGHCP"/>
    <dbReference type="OrthoDB" id="1288973at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_11" evidence="1">
        <location>
            <begin position="5"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="23503" checksum="ECDC437F5C0B3AEC" modified="2008-04-29" version="1">MKTSEKIIQLLKTQGPQTAKVLATELSLTTMGVRQHMQVLEDEGDVSFEDIKASRGRPTRVWSLTAKSNSHFTDRHEELSVQLIDSVINVFGDSGLDKLISHREETSLAMYQERLSVEKTLLGKLNALVELRTAEGYMASVEQEDDFYWLLENHCPICAAASRCLNFCRSELKQFQTLLQEDASVSREEHIIEGARRCAYKVQPIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS8</accession>
    <name>B1KGS8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type VI secretion ATPase, ClpV1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325138.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2520"/>
    <dbReference type="EnsemblBacteria" id="ACA86797">
        <property type="protein sequence ID" value="ACA86797"/>
        <property type="gene ID" value="Swoo_2520"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2520"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_2_0_6"/>
    <dbReference type="OMA" id="CKNVVFF"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017729">
        <property type="entry name" value="ATPase_T6SS_ClpV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03345">
        <property type="entry name" value="VI_ClpV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="8">
        <location>
            <begin position="10"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="863" mass="95324" checksum="FF85AB9495F9EB0D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT5</accession>
    <name>B1KGT5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type VI secretion system lysozyme-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325145.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2527"/>
    <dbReference type="EnsemblBacteria" id="ACA86804">
        <property type="protein sequence ID" value="ACA86804"/>
        <property type="gene ID" value="Swoo_2527"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2527"/>
    <dbReference type="eggNOG" id="COG3518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132637_3_0_6"/>
    <dbReference type="OMA" id="PMEMSFQ"/>
    <dbReference type="OrthoDB" id="1918415at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007048">
        <property type="entry name" value="IraD/Gp25-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017737">
        <property type="entry name" value="TssE1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04965">
        <property type="entry name" value="GPW_gp25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03357">
        <property type="entry name" value="VI_zyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPW_gp25" evidence="1">
        <location>
            <begin position="35"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="141" mass="15965" checksum="A3BFDA61AB038C30" modified="2008-04-29" version="1">MFNHDDTFGVSFFQRLGDENEHASNGSESIEYVIASIKRNISGLLNTRVGESQSCPELGLFDFNDANSGSFDLGVRIKAGIKTCIERFEPRLTHLDIRVLHDTSCPFSLRFHIHGKINVKTAQEKIEIDLFLDSNRTYRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGY6</accession>
    <name>B1KGY6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326627.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4042"/>
    <dbReference type="EnsemblBacteria" id="ACA88298">
        <property type="protein sequence ID" value="ACA88298"/>
        <property type="gene ID" value="Swoo_4042"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4042"/>
    <dbReference type="eggNOG" id="ENOG502Z7R8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079573_0_0_6"/>
    <dbReference type="OMA" id="TDNDFWR"/>
    <dbReference type="OrthoDB" id="1083282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="281" mass="33012" checksum="4E71F5BF30B64B9C" modified="2008-04-29" version="1">MSNKEQSAFIRAIGSDNSLPIEKAAVDLWVKDLDNPFRWTLRPILQFLFAILLHLTWFFKRLPLPQFSGHSLLQKMICWFCKNLVSPEANLLILRHFSTESNVINFLAENSGKEVVVDLYPKCVDDMIRDTFVKHDQELFDAFYHLGDAKDAQKIARTKLKWKHWQKIDMKAFELDRKLTQVIDFETAHALFMCLFCFLLKRDEYRDAINGFNLDQSIAIRIGRIIGKPEIVEMAYNKYPHYLVGPWNLSQRFLMHGFFTEYLYAELESIRNDAMSTSNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH10</accession>
    <name>B1KH10_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326651.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4066"/>
    <dbReference type="EnsemblBacteria" id="ACA88322">
        <property type="protein sequence ID" value="ACA88322"/>
        <property type="gene ID" value="Swoo_4066"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4066"/>
    <dbReference type="HOGENOM" id="CLU_2702780_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764867" evidence="2">
        <location>
            <begin position="23"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="73" mass="8268" checksum="CDC129586B68EE6A" modified="2008-04-29" version="1" precursor="true">MMLYTKLILLISILFFSTATYAAEPEHDDKAHEKAEKNLDDKHWNDAHGSGVPEKKGRNPGGKKESKSKKEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH23</accession>
    <name>B1KH23_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4079"/>
    <dbReference type="EnsemblBacteria" id="ACA88335">
        <property type="protein sequence ID" value="ACA88335"/>
        <property type="gene ID" value="Swoo_4079"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4079"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_2_5_6"/>
    <dbReference type="OMA" id="WQGINLE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767050" evidence="1">
        <location>
            <begin position="24"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="28"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="276" mass="30355" checksum="A63FBAB5C9E89DF6" modified="2008-04-29" version="1" precursor="true">MQHSVKRLLVAMVCFLSVSVAVAAPAKRVIALSPHSVEMLYAIGAGETIVATTDHADFPAAALDIPRIGGYHGVQIERVIELNPDLVLVWGSGNKAEDIDRIKSLGFKVFDSDPKTLEAVADELKALGELTGNKAQANRVGDEYLTQLAKLRKDNLAKQKVKVFYQLWSTPLMTVAKNSWIQQIIDVCHGDNVYIDAASDYPQVSLESVLLKMPEVILQSQDEGNVLGVDWNKWQEIPAVKQQHIYQLNADLLHRAAPRALLGVNALCEALDKARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH52</accession>
    <name>B1KH52_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CrtC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326693.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4108"/>
    <dbReference type="EnsemblBacteria" id="ACA88364">
        <property type="protein sequence ID" value="ACA88364"/>
        <property type="gene ID" value="Swoo_4108"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4108"/>
    <dbReference type="eggNOG" id="COG5621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040626_0_0_6"/>
    <dbReference type="OMA" id="AWLDHEW"/>
    <dbReference type="OrthoDB" id="591394at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.370.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023374">
        <property type="entry name" value="AttH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010791">
        <property type="entry name" value="AttH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07143">
        <property type="entry name" value="CrtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CrtC" evidence="1">
        <location>
            <begin position="80"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="390" mass="44013" checksum="905415FBD642F8F2" modified="2008-04-29" version="1" precursor="true">MAIVQIQITRKNITAIILALTISFMLFACSKAQNTEQAVSMGKLMGHSQEGAGQTYTPVEKSRAISFPQDHLAHNDFRQEWWYLTANLETEQGKKLGLQWTQFRIALTPEELFSASDEKTENEQSEKNSWVSKQLYMTHAAVTTQEQHFAEERWSRQHPMLADVSTAPLTIKIDNWRWIGTGDELFPASLAVDGDQFSYQLSLNANAPYQLQGEQGYSIKSADGSVASHYYSQPFIQVSGQVTLQGESHQVTGEAWLDREWSSQFLNKDQAGWDWFALRLDDGSTLMLFQLRGEPDSETSFYSGRRMFADGSGRNIGSDEIAIEVLDWHQIDTSRYPISWKINIPSESIQLTTQALNPDAKIPLSISYWEGPVVISGSHQGEGYMELTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH91</accession>
    <name>B1KH91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323745.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1106"/>
    <dbReference type="EnsemblBacteria" id="ACA85399">
        <property type="protein sequence ID" value="ACA85399"/>
        <property type="gene ID" value="Swoo_1106"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1106"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102543_2_1_6"/>
    <dbReference type="OMA" id="AVCFKAP"/>
    <dbReference type="OrthoDB" id="1814691at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027961">
        <property type="entry name" value="DUF4442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14539">
        <property type="entry name" value="DUF4442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="159" mass="17886" checksum="57C6CA42BA32ABA9" modified="2008-04-29" version="1">MTTQKPTKVMALYNRVTRFPFGNKIFSIMVARMAPYFGTIKPLITELRPHRCECLIKKRHAVHNHIKTVHVIAICNGLEMAMGVMAEASIPHHLRWIPKGMSLDYTAKAGSDIRCVAQVNPEQWVPGDLMVPVTAYDSEGVVVVKGEIKLWISEKPAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHB4</accession>
    <name>B1KHB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase C26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323768.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1129"/>
    <dbReference type="MEROPS" id="C26.961"/>
    <dbReference type="EnsemblBacteria" id="ACA85422">
        <property type="protein sequence ID" value="ACA85422"/>
        <property type="gene ID" value="Swoo_1129"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1129"/>
    <dbReference type="eggNOG" id="COG2071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030756_0_0_6"/>
    <dbReference type="OMA" id="PTYHHQA"/>
    <dbReference type="OrthoDB" id="1628378at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="253" mass="27683" checksum="0AF81FB26FB777C3" modified="2008-04-29" version="1">MSDAGLAVIGVTACNQKLGLHPFNIVGEKYLLSIADATNAWPLVIPSLGHCPAESILPRLDGILFTGSPSNIEPHHFQGQPSEADTHHDPKRDATTLPLLKAAIDAGVPVLAICRGFQEMNVVYGGTLHQKLHEVGGYIEHREDKTKPVDVQYGISHEVQIEPGGLLHEAWGRSSAEVNSVHTQGVDRLGVGLRPEAFASDGLVEAFSVREAKNFALGVQWHPEWKVLEHPFYTAIFKLFSDACQRHAMNRVR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF6</accession>
    <name>GSA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="1">GSA</shortName>
            <ecNumber evidence="1">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="1">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hemL</name>
        <name type="ordered locus">Swoo_1171</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323810.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHF6"/>
    <dbReference type="SMR" id="B1KHF6"/>
    <dbReference type="STRING" id="392500.Swoo_1171"/>
    <dbReference type="EnsemblBacteria" id="ACA85464">
        <property type="protein sequence ID" value="ACA85464"/>
        <property type="gene ID" value="Swoo_1171"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1171"/>
    <dbReference type="eggNOG" id="COG0001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_1_5_6"/>
    <dbReference type="OMA" id="WGPLIFG"/>
    <dbReference type="OrthoDB" id="493793at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000121922" description="Glutamate-1-semialdehyde 2,1-aminomutase">
        <location>
            <begin position="1"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <sequence length="428" mass="46124" checksum="EFEB3A5947A4B0B9" modified="2008-04-29" version="1">MTRSDELFEQAKKTIPGGVNSPVRAFNGVGGSPRFIDKADGAYIYDADGKAYIDYVGSWGPMILGHNHPKIRQAVLEAVENGLSFGAPTELEVKMAEKVIEMVPSMEQVRMVSSGTEATMSAIRLARGFTNRDKILKFEGCYHGHADCLLVKAGSGALTLGQPSSPGIPEDFAKHTLTATYNELESVKTLFEQYPEEISCIILEPVAGNMNCIPPVEGFLEGLRAICDQYGALLIIDEVMTGFRVSKSGAQGHYGITPDLTTLGKVIGGGMPVGAFGGRKDVMQFIAPTGPVYQAGTLSGNPIAMSAGLAQMEELCAEGLYQELAAKTKRIAEGFKAAANKHGIPMSINYVGGMFGFFFTEEEKVTRFDQVTQCDAEKFPEFYHGMLDEGVYLAPSAYEAGFLSMAHGEKELEETLAAAERVFAKMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH8</accession>
    <name>B1KHH8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flg_bbr_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2586</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325203.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2586"/>
    <dbReference type="EnsemblBacteria" id="ACA86863">
        <property type="protein sequence ID" value="ACA86863"/>
        <property type="gene ID" value="Swoo_2586"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2586"/>
    <dbReference type="eggNOG" id="ENOG5033C47">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_185336_0_0_6"/>
    <dbReference type="OMA" id="IESKNQG"/>
    <dbReference type="OrthoDB" id="1917538at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bbr_C" evidence="3">
        <location>
            <begin position="13"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="90" mass="9249" checksum="ED2056912406F87D" modified="2008-04-29" version="1">MQIPPSFSSGQVGLQSAQTGLTQATVDVASPTPPAQPTQSAETQEARPVENVDKTEALVSAVEAQNQGEAAAEVLETSSETLGTIINIEV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHI4</accession>
    <name>THIC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="1">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="1">HMP-P synthase</shortName>
            <shortName evidence="1">HMP-phosphate synthase</shortName>
            <shortName evidence="1">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thiC</name>
        <name type="ordered locus">Swoo_2592</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThiC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325209.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHI4"/>
    <dbReference type="SMR" id="B1KHI4"/>
    <dbReference type="STRING" id="392500.Swoo_2592"/>
    <dbReference type="EnsemblBacteria" id="ACA86869">
        <property type="protein sequence ID" value="ACA86869"/>
        <property type="gene ID" value="Swoo_2592"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2592"/>
    <dbReference type="eggNOG" id="COG0422">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013181_2_1_6"/>
    <dbReference type="OMA" id="TWELFRD"/>
    <dbReference type="OrthoDB" id="505395at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025747">
        <property type="entry name" value="ThiC-associated_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13667">
        <property type="entry name" value="ThiC-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000093235" description="Phosphomethylpyrimidine synthase">
        <location>
            <begin position="1"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="349"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="390"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="577"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="580"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="585"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <sequence length="652" mass="72479" checksum="495B085759DCC9A6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ6</accession>
    <name>B1KHJ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A dehydrogenase</fullName>
            <ecNumber evidence="6">1.3.8.7</ecNumber>
            <ecNumber evidence="7">1.3.8.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2604</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:17721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83721"/>
            <dbReference type="ChEBI" id="CHEBI:83727"/>
            <dbReference type="EC" id="1.3.8.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:14477"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83723"/>
            <dbReference type="ChEBI" id="CHEBI:83726"/>
            <dbReference type="EC" id="1.3.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="6"/>
    <dbReference type="EC" id="1.3.8.8" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325221.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2604"/>
    <dbReference type="EnsemblBacteria" id="ACA86881">
        <property type="protein sequence ID" value="ACA86881"/>
        <property type="gene ID" value="Swoo_2604"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2604"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012192_0_0_6"/>
    <dbReference type="OMA" id="SAYAHSQ"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004466">
        <property type="term" value="F:long-chain-acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015396">
        <property type="entry name" value="DUF1974"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09317">
        <property type="entry name" value="DUF1974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="12">
        <location>
            <begin position="123"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="11">
        <location>
            <begin position="361"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1974" evidence="13">
        <location>
            <begin position="515"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="815" mass="89553" checksum="A060AA7C545E978B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHM6</accession>
    <name>B1KHM6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitrate reductase (quinone)</fullName>
            <ecNumber evidence="7">1.7.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_2634</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinol + nitrate = a quinone + H2O + nitrite</text>
            <dbReference type="Rhea" id="RHEA:56144"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.7.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.5.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2634"/>
    <dbReference type="EnsemblBacteria" id="ACA86911">
        <property type="protein sequence ID" value="ACA86911"/>
        <property type="gene ID" value="Swoo_2634"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2634"/>
    <dbReference type="eggNOG" id="COG5013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_14_1_6"/>
    <dbReference type="OMA" id="GGHHNSV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042126">
        <property type="term" value="P:nitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02776">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037943">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006468">
        <property type="entry name" value="NarG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028189">
        <property type="entry name" value="Nitr_red_alph_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044906">
        <property type="entry name" value="Nitr_red_alph_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14710">
        <property type="entry name" value="Nitr_red_alph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01580">
        <property type="entry name" value="narG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00932">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="14">
        <location>
            <begin position="56"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA86911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1267" mass="142520" checksum="350403FB8671ED0C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHU1</accession>
    <name>B1KHU1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. HSP26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326748.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4163"/>
    <dbReference type="EnsemblBacteria" id="ACA88419">
        <property type="protein sequence ID" value="ACA88419"/>
        <property type="gene ID" value="Swoo_4163"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4163"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_9_3_6"/>
    <dbReference type="OMA" id="ADHYSHR"/>
    <dbReference type="OrthoDB" id="1997747at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03186">
        <property type="entry name" value="GST_C_SspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03059">
        <property type="entry name" value="GST_N_SspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034342">
        <property type="entry name" value="SspA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034341">
        <property type="entry name" value="SspA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="92"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="24114" checksum="A2563F3F3614E217" modified="2008-04-29" version="1">MAVAANKRSIMTLYSGADDLYSHQVRIVLAEKGVTVDVLQVEPSEMPEDLIELNPYNTVPTLVDRELVLYNSRIIMEYLDERFPHPPLMPVYPVSRGRTRLMMHRIQHDWYTLVERIRTGDRADAARKELQEGLTAIAPVFSEMPYFMAEEFGLADCYLGPLLWRLPVLGIELDIRTAKEVKAYMTRLFDRESFKASLTEAEREMRMGA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHU8</accession>
    <name>HFQ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein Hfq</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hfq</name>
        <name type="ordered locus">Swoo_4170</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Hfq family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326755.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHU8"/>
    <dbReference type="SMR" id="B1KHU8"/>
    <dbReference type="STRING" id="392500.Swoo_4170"/>
    <dbReference type="EnsemblBacteria" id="ACA88426">
        <property type="protein sequence ID" value="ACA88426"/>
        <property type="gene ID" value="Swoo_4170"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4170"/>
    <dbReference type="eggNOG" id="COG1923">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113688_2_2_6"/>
    <dbReference type="OMA" id="QQMVYKH"/>
    <dbReference type="OrthoDB" id="1989988at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01716">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00436">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005001">
        <property type="entry name" value="Hfq"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34772">
        <property type="entry name" value="PTHR34772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17209">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02383">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_1000190360" description="RNA-binding protein Hfq">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="94" mass="10279" checksum="5449643C1580CCF8" modified="2008-04-29" version="1">MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPARPFNVSAHHSSPAPTPAGGFNGQNDETSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI64</accession>
    <name>B1KI64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323888.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1250"/>
    <dbReference type="EnsemblBacteria" id="ACA85542">
        <property type="protein sequence ID" value="ACA85542"/>
        <property type="gene ID" value="Swoo_1250"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1250"/>
    <dbReference type="eggNOG" id="COG4539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081702_2_0_6"/>
    <dbReference type="OMA" id="IQFIGHY"/>
    <dbReference type="OrthoDB" id="1934114at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="PTHR28026"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="DUF962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="181" mass="20380" checksum="FD7953D1E16984D2" modified="2008-04-29" version="1">MKSAEEQLSTYKSVHLNPKNIKTHFVGIPLIIWSLFLLLNLIPVTFFALDTPAISINVASVFAIGVLLYYIKLHARLALGLALFIIPVLYTSSLVAQVQGALWIALAVFVIGWVFQLIGHQYEKAKPAFIDDLNQLLIGPFFLMAEVYFLLGLEKELDKQITPMAVDKRRALEDERRAARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIJ9</accession>
    <name>B1KIJ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipopolysaccharide export system ATP-binding protein LptB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_4239</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326822.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4239"/>
    <dbReference type="EnsemblBacteria" id="ACA88495">
        <property type="protein sequence ID" value="ACA88495"/>
        <property type="gene ID" value="Swoo_4239"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4239"/>
    <dbReference type="eggNOG" id="COG1137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="LPMYQRA"/>
    <dbReference type="OrthoDB" id="1220708at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="6"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA88495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="243" mass="26925" checksum="0CC6BAE6104F14C3" modified="2008-04-29" version="1">MSSLTLKAVNLAKSYKSRAVVQDVSLSVKTGQIVGLLGPNGAGKTTTFYMVVGLVQSDKGRIFIDSDDLTLDPMHLRARKGIGYLPQEASIFRKLSVRDNIMAVLQTRDELDKNAREEQLEHLLEEFHITHIRDSQGMSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKKIILQLKSRGLGVLITDHNVRETLDVCEHAYIVSHGNLIAEGTPAEILDNQQVRAVYLGEQFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ07</accession>
    <name>B1KJ07_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324001.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85655">
        <property type="protein sequence ID" value="ACA85655"/>
        <property type="gene ID" value="Swoo_1363"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1363"/>
    <dbReference type="HOGENOM" id="CLU_2958219_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="59" mass="6467" checksum="8605F499943850C6" modified="2008-04-29" version="1">MGSNATTNRADTLTITVCTVVEALATERFTAVISDDIEDILFTFSMLLFIILRVNLDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ19</accession>
    <name>B1KJ19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87039">
        <property type="protein sequence ID" value="ACA87039"/>
        <property type="gene ID" value="Swoo_2763"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2763"/>
    <dbReference type="eggNOG" id="ENOG5033CHF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128216_0_0_6"/>
    <dbReference type="OMA" id="EIRGECN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19563" checksum="42A668ED472ADD1B" modified="2008-04-29" version="1">MVGHGLYIPCNSNLSQTDVDTKIIRTDMLNNKIALMLSLTLLTACASKKTDPEDFKLSVKDRFSTNIKGDGIKLFTYKAQLANLAEPDFPLPHNERIEQVKRKSRAQSGKRYKQPDLSDWTQQIELGLSKTLAMTGYCREGFMELSRIIEVGRAEIRGECNEGATEADKQKFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ54</accession>
    <name>B1KJ54_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325410.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87074">
        <property type="protein sequence ID" value="ACA87074"/>
        <property type="gene ID" value="Swoo_2799"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2799"/>
    <dbReference type="eggNOG" id="ENOG50315UU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1011550_0_0_6"/>
    <dbReference type="OMA" id="ENDITHV"/>
    <dbReference type="OrthoDB" id="2177719at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764557" evidence="1">
        <location>
            <begin position="23"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="241" mass="27377" checksum="BC55016D20826DF7" modified="2008-04-29" version="1" precursor="true">MKLDKLATLLACTTLLTFSINAAPTHVRHMESNGNETVMEIAQDENELTHISVKQGDDKHEFTFTADELSDPSAIKEKLSALPEKTSRKLTRVLTKMTVLDQDKFKLLHNKEMDIKTKEKLAAIARKMEGKEVEMEFIARKLEAKAAELEAHALELESLHELKEGEYEIIIDTFENSIAEVMSSLGEIEVDIDFDHESGHTSRFVIIDDHQGINHTQHLIRMIKNSELTEEQKQAIKDALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ60</accession>
    <name>B1KJ60_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2805</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325416.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2805"/>
    <dbReference type="EnsemblBacteria" id="ACA87080">
        <property type="protein sequence ID" value="ACA87080"/>
        <property type="gene ID" value="Swoo_2805"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2805"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_42_2_6"/>
    <dbReference type="OMA" id="FFVYDVE"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="248"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="449" mass="50623" checksum="F639BCF9AAE8EF63" modified="2008-04-29" version="1" precursor="true">MQLKFKPKKRLLTRMFLTSLSIIALVGFGLAWMINILHAQNSYNEETAQLIAEIPKVAAELKEHDLIPETSEWLDENNTPERYVIASCDADFRQVWTSSLAVDKGLFDTCERFNEIRNDSPPYYLNLADEKGYFIYLLAVEIAGNKYNLLVMKDAENLEAELDKFSRLTYIRLAMVLALALVLLISAGYWGMRPLVRMRSELESVNNGKSKSLSQDYPVELEGVTQALNQLLVQSSAQQDRYQNAMNDLAHSLKTRLAAVHAITDDINLDKHSASEKIMEQVSQMDLLVKYQLKRAMLGRKGLKQEQTLVAPLVNQLSQMLFKVYRDKQVMFEAHIPIEHVFPGDKGDLMELCGNLMENAFKLCISQVRVSASYNDHGEFLLVVEDDGQGVDDSIKQKIIQRGVRADTQKAGQGIGLAVCHEIVTSYGGKLEIEDSDLEGAKFIITIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ69</accession>
    <name>B1KJ69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2814</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325425.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2814"/>
    <dbReference type="EnsemblBacteria" id="ACA87089">
        <property type="protein sequence ID" value="ACA87089"/>
        <property type="gene ID" value="Swoo_2814"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2814"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="RCTHEIN"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="371"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="430"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="702" mass="76983" checksum="F559DA7E2ABC5D79" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ75</accession>
    <name>B1KJ75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325431.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2820"/>
    <dbReference type="EnsemblBacteria" id="ACA87095">
        <property type="protein sequence ID" value="ACA87095"/>
        <property type="gene ID" value="Swoo_2820"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2820"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_9_0_6"/>
    <dbReference type="OMA" id="WAGMRPA"/>
    <dbReference type="OrthoDB" id="573710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DAO" evidence="4">
        <location>
            <begin position="19"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="432" mass="47150" checksum="F01465A6E522157D" modified="2008-04-29" version="1">MTKINHREHKQSNKKAIKVTVIGAGIVGLATGIELQRAGFQVEIIDKEGVGAGASQGNAGHFATEQVFPLADPSLLPKLPGMLLDPLGPFRIRPAYFFKALPWFCRFLINMLPSKRLHNGQGIKRLNQASITAMEELTSFCNCEELLLLNGSLLVFEGTAIDEVDKEFTHYRDAGVEVKLLTGEEVRALEPSLSQSVTHGLFFTHVGHTNDPYQLCQAFSQKFIALGGELSTGELGKIEPVGGGETGINLALSSGYIANTDKIVIASGAWSKPLVKQLGHKVPLEAERGYHLMMPQKSSLSRPVASYNRKFIITPMTEGTRLAGTVEFGGLQAPLNESRADCLFPHGKALLPSLFADAKVSDGERWMGFRPSLPDSLPVLGSSSNHKNVFFSFGHQHLGLTWSAITAKLLAQQMSGEQPDIDLSDYRVERFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ89</accession>
    <name>B1KJ89_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exonuclease RNase T and DNA polymerase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2834</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2834"/>
    <dbReference type="EnsemblBacteria" id="ACA87109">
        <property type="protein sequence ID" value="ACA87109"/>
        <property type="gene ID" value="Swoo_2834"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2834"/>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047806_9_0_6"/>
    <dbReference type="OMA" id="PVYAAHN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="3">
        <location>
            <begin position="42"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25137" checksum="22003C2A1130FC67" modified="2008-04-29" version="1">MLSRYLLKSKLCWRAFRAEDQALKTYYHGQQSLLELDVERAPLLAIDLEMTGLDAQFDQILSIGIVPIEKGRLILSKAEHKLVKIEGSVGQSATIHGILDHHLNSAVSPEEAMTWFLERCQGQMLVAHHSPLDLAFLQKGLSTHFRQRVTLMAIDTLAIEKRRLMRQHEVLKEGALRLGASRARYGLPVYAAHNALIDAIACGELLLAQISAIGQGESVKLTELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD8</accession>
    <name>B1KJD8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326936.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4357"/>
    <dbReference type="EnsemblBacteria" id="ACA88610">
        <property type="protein sequence ID" value="ACA88610"/>
        <property type="gene ID" value="Swoo_4357"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4357"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_3_4_6"/>
    <dbReference type="OMA" id="QYETIAF"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="17"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="274"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="528" mass="58994" checksum="37E2D83C8CCB0BC0" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL2</accession>
    <name>B1KJL2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324031.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1393"/>
    <dbReference type="EnsemblBacteria" id="ACA85685">
        <property type="protein sequence ID" value="ACA85685"/>
        <property type="gene ID" value="Swoo_1393"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1393"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_6"/>
    <dbReference type="OMA" id="THRIREM"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="308" mass="34983" checksum="AFF4A824E32D0837" modified="2008-04-29" version="1">MDITKTQLNINHLKMICTIAKSETVKEAAESLFITQPALTNRIREAERRLNTSLFVRRGRKLIISNAGKRLLHSAKKILEELGRAEYDIARLSDGVEQVLRIGLPHYASFKWLPAVTSYFAKELPNIELEITAAAAKRPLNALFNGDVDIAMISSSQQKLSLDENLYESSFLLQDELMACLSKDHKKAERNHLVAEDFIDETYITNSTIPEKDREYELFFQPENVLPRKVLQVGFNEAILELTKVNLGVTIMSKHLVSPYLENGMIRTVPLGEQGLKIYWHLVYLKQGKIAKPAKVLTTILKQYANES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW9</accession>
    <name>B1KJW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325492.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87156">
        <property type="protein sequence ID" value="ACA87156"/>
        <property type="gene ID" value="Swoo_2881"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2881"/>
    <dbReference type="HOGENOM" id="CLU_2439126_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="90" mass="10568" checksum="EE00F594EAA0EA09" modified="2008-04-29" version="1">MYGRDFCIKLTYIDVKLELLTLIRLRLILGTILSLNRELLPGLNCKNKNRIKTASYIDSSFLYYFNILKHHLSLINYIDAGDNEYQILLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJX3</accession>
    <name>B1KJX3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UPF0208 membrane protein YfbV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0208 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2885"/>
    <dbReference type="EnsemblBacteria" id="ACA87160">
        <property type="protein sequence ID" value="ACA87160"/>
        <property type="gene ID" value="Swoo_2885"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2885"/>
    <dbReference type="eggNOG" id="COG3092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128746_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007334">
        <property type="entry name" value="UPF0208"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04217">
        <property type="entry name" value="DUF412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="132" mass="15344" checksum="9E37B2C46C8DB8F7" modified="2008-04-29" version="1">MKTWPMVRQLSFYFPEYRVIRATQIALPVMPILALLAAASQLYIHGWEFLPQAITLGLFFISLPIQGLLWLGWRSRHPLPLTLLEWCDKLTTKMIAMGISCRPLGPKACYFDMALILKAAFERLDEQYWEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK25</accession>
    <name>B1KK25_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA biogenesis protein MshP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326982.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4404"/>
    <dbReference type="EnsemblBacteria" id="ACA88656">
        <property type="protein sequence ID" value="ACA88656"/>
        <property type="gene ID" value="Swoo_4404"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4404"/>
    <dbReference type="eggNOG" id="COG4726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123901_0_0_6"/>
    <dbReference type="OMA" id="TQYRINS"/>
    <dbReference type="OrthoDB" id="1989641at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="167" mass="17736" checksum="20D8542DBB7C3275" modified="2008-04-29" version="1" precursor="true">MSHSLSSLLTGSRGTYLRSELSRQSGSALIIGIFVITVMFLMATALLNVLEDADEQVNLEVWGTRAFAAANSGADRALSQLFPLTATDNTATSCTNVTSSWNIGNDNPTLVGFHACSIVITCDDTNTINTVTQYLITSTATCQTGDCASNDGNCLRVSRSVEVEARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK71</accession>
    <name>B1KK71_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NosL family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327028.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4450"/>
    <dbReference type="EnsemblBacteria" id="ACA88702">
        <property type="protein sequence ID" value="ACA88702"/>
        <property type="gene ID" value="Swoo_4450"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4450"/>
    <dbReference type="eggNOG" id="COG4314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096026_0_0_6"/>
    <dbReference type="OMA" id="ATKAWYV"/>
    <dbReference type="OrthoDB" id="1678497at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008719">
        <property type="entry name" value="N2O_reductase_NosL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41247">
        <property type="entry name" value="PTHR41247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05573">
        <property type="entry name" value="NosL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764595" evidence="1">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="17781" checksum="625B2DDCC9CA5322" modified="2008-04-29" version="1" precursor="true">MKKLICLILLIPSLIACSQGNSVPEQLVAQSISEHGRCHLCGMMITKYPGPKGALQLKSAELSPKFCSTRDMFNFALQPENKRQISHLMVHDMSVTEWEDPQDTSFIDATKAWYVYGTSRKAVMGSAVASFSTKESAEAFAEEFGGAVLQYEQITLGLLAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK75</accession>
    <name>B1KK75_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4454</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327032.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4454"/>
    <dbReference type="EnsemblBacteria" id="ACA88706">
        <property type="protein sequence ID" value="ACA88706"/>
        <property type="gene ID" value="Swoo_4454"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4454"/>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_0_2_6"/>
    <dbReference type="OMA" id="LAYGNEF"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766742" description="Peptidyl-prolyl cis-trans isomerase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="152"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="28360" checksum="EF76F92EC5CEADA2" modified="2008-04-29" version="1" precursor="true">MKTFKRNTLAVMTSVSLLISANAMANTEISSDVQKESYSIGASLGKYISGQIYSQTELGAEVDVELVIEGVVDALKNKPQFSDEEILTFLNQRAEQLNTAREAAEAKIALENLTAGNKYLTENKAKDGVNETASGLQYEVISEGEGRKPNPQDVVTVHYKGFLVDGTPFDDSYERNEPNRFALMSVIEGWQEGIPLMNEGSKYKFAIPAALAYGEKQVGIIPPSSTLVFEVELVKVEAPGEGAHGMGLSGMGMGGMMGQGNPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD1</accession>
    <name>B1KKD1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324117.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1483"/>
    <dbReference type="EnsemblBacteria" id="ACA85771">
        <property type="protein sequence ID" value="ACA85771"/>
        <property type="gene ID" value="Swoo_1483"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1483"/>
    <dbReference type="eggNOG" id="ENOG5031F6W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1676658_0_0_6"/>
    <dbReference type="OMA" id="QRRATEW"/>
    <dbReference type="OrthoDB" id="2120233at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767432" evidence="1">
        <location>
            <begin position="33"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="157" mass="16986" checksum="1E31B8A34F961596" modified="2008-04-29" version="1" precursor="true">MLGFKAKEMRRLFYVVTKLALFAALLTGCSVAYQPSNGVKEGYQDFMLPSGCIVLTYVGNGRATASALQEVWQRRATEWCPTGFDIVSMNRDIRHGSMVSPVGGGDARLGTQTPVLSGVFKCMGGIEHISGSVQASEQDRKFIQLAADIWSNNPSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH9</accession>
    <name>B1KKH9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1531"/>
    <dbReference type="EnsemblBacteria" id="ACA85819">
        <property type="protein sequence ID" value="ACA85819"/>
        <property type="gene ID" value="Swoo_1531"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1531"/>
    <dbReference type="eggNOG" id="COG3228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063037_0_1_6"/>
    <dbReference type="OMA" id="EHSGEAW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd20169">
        <property type="entry name" value="Peptidase_M90_mtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010384">
        <property type="entry name" value="MtfA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042252">
        <property type="entry name" value="MtfA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30164">
        <property type="entry name" value="PTHR30164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06167">
        <property type="entry name" value="Peptidase_M90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="32098" checksum="8851EC058915BB0C" modified="2008-04-29" version="1">MDKTSMLAIVIVSLLALFSIFWIASRSWRIARHRASVTATPFPASWRIILKQRMPYFRSLPADLQLQLKDLIQVFIDEKEFIGCDGIVIDDEIRVTIAAQACLLLLNRKTDFYPKLKQILVYPSVFIVKNHELRSGGVVGDKKRLLSGESWENGKVVLSWQTTQDDAADPRDGSNVVIHEFAHQLDQEDGNANGAPILSSLDDYSSWSEVLSREFERLQYQAEQNTPSIFSYYGATNPAEFFAVITEVFFEQPQEFYQSHRELYTELSHFFKLDPINWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP0</accession>
    <name>B1KKP0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="12">ASA dehydrogenase</shortName>
            <shortName evidence="12">ASADH</shortName>
            <ecNumber evidence="7 12">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">asd</name>
        <name evidence="14" type="ordered locus">Swoo_2986</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325593.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2986"/>
    <dbReference type="EnsemblBacteria" id="ACA87257">
        <property type="protein sequence ID" value="ACA87257"/>
        <property type="gene ID" value="Swoo_2986"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2986"/>
    <dbReference type="eggNOG" id="COG0136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049966_0_1_6"/>
    <dbReference type="OMA" id="CEEEMKM"/>
    <dbReference type="OrthoDB" id="1799040at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="13">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="41"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="162"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="338" mass="37132" checksum="999F97B6C2983050" modified="2008-04-29" version="1">MSQEFNVVVLGATGAVGQTMIEILEERNFPVANLFPLASSRSAGNTVSFHGKQVEILDVDKFDWSQAQIGFFSAGGDVSAKWAPIAAEHGCVVIDNTSHFRYDIDVPLVVPEVNPQAIADFRNRNIIANPNCSTIQMLVALKPIYDAFGISRINVATYQSVSGSGKQAIEELASQCAKLLQGLPIEPKAYPKQIAFNALPHIDKFMDNGYTKEEMKMVWETQKIFGDESIVVNPTAVRVPVFHGHSEAIHLETLQPVDAEDVKSVLRDAPGVELFESDEEYPTVVTDAAGCDPVYVGRVRKDISHENGINLWVVSDNIRKGAALNSIQIAEVLIRDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP4</accession>
    <name>B1KKP4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325597.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2990"/>
    <dbReference type="EnsemblBacteria" id="ACA87261">
        <property type="protein sequence ID" value="ACA87261"/>
        <property type="gene ID" value="Swoo_2990"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2990"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064076_1_1_6"/>
    <dbReference type="OMA" id="RFWCQAD"/>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764617" evidence="2">
        <location>
            <begin position="25"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="29"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="29496" checksum="6C011ABF7D2240FA" modified="2008-04-29" version="1" precursor="true">MGRCFKSGFFSIFLSLLLICQSIADESVELRLLTEPWAPVSYDDAGIASGFAVELVNELQRIMGTELEIEVLPWARALSIANSLPNVVLFATSVDEERRKNFDFVGPIITSKISLYAKANDHIEINSLEELNHAGSIGTYRSAIGLEMLKELGLTQLLVSSFPHQSAKQLIKGRVRFWCQADIAVASLLTKIGANIDSVKPVFVLSEIELYLAFSKGTELEVIKQWQSALAYYKASGKFKRLYYKWFGDLPVPERVELIRRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKP8</accession>
    <name>B1KKP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BNR repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325601.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2994"/>
    <dbReference type="EnsemblBacteria" id="ACA87265">
        <property type="protein sequence ID" value="ACA87265"/>
        <property type="gene ID" value="Swoo_2994"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2994"/>
    <dbReference type="eggNOG" id="COG4409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_658671_0_0_6"/>
    <dbReference type="OMA" id="SCECCRI"/>
    <dbReference type="OrthoDB" id="1293876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="416" mass="47307" checksum="372EDBF8C30FF2D4" modified="2008-04-29" version="1" precursor="true">MVKLPMIKVNHLIVLLIICIPLKFTDVKAAHEHHKMQSQTDGRITCTQQEINCAKTVTSSFAPNGDLWRLWAHKDSMYFQTSQNKGVTFSSIRRVPIPKESISARNENRPKIAFDQYQGVYLSWAMPKAKKYTADVRFSYSKDYGASFSRPVTVNNDKLEIGHSFNEMQVTAEGEITLVWLDSRLAHQARAQGEQTNGSSLYLGRANYRKQQLTFSNRPLANNTCVCCRIAMDINKLGETVILWRHIYNDNIREFALLTLEQDEKTQHPPYQISHDRWQIDGCPHQGGGLSIDSSNRYHMVWFNQGELGKGIFYASSLDQGQSLTKPVSIGQQSAQAAHPHVNTLGSRVDIVWTQFNGTEHQLWHQYSDNNGQSFSQARLLTTASAGADRPFIITNNNISFVSWHRLKQGHWIQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR9</accession>
    <name>B1KKR9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-NAD/AcoX kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325622.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3015"/>
    <dbReference type="EnsemblBacteria" id="ACA87286">
        <property type="protein sequence ID" value="ACA87286"/>
        <property type="gene ID" value="Swoo_3015"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3015"/>
    <dbReference type="eggNOG" id="COG3199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064691_0_0_6"/>
    <dbReference type="OMA" id="RGNQQFS"/>
    <dbReference type="OrthoDB" id="869726at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039065">
        <property type="entry name" value="AcoX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011386">
        <property type="entry name" value="Put_ATP-NAD_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40697">
        <property type="entry name" value="PTHR40697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016907">
        <property type="entry name" value="Kin_ATP-NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="374" mass="40287" checksum="922CB2BACAD3E8C7" modified="2008-04-29" version="1" precursor="true">MTIRFRLGLIINPLAGLGGSVALKGSDGVADEALARGAKPKSHLRMQQALEVILPYRDRIEIITASGSMGESLAKEMGFGVRVVHRVGEETEATDTQAVVKVLLEETLDLLLFAGGDGTARDIYEVAGDDLPVLGVPAGVKIHSGVYGITPHASGTVVKMLLDGELVSLMNADVMDIDETAFRQGIVKARRFGEMLVPAEPRYIQSVKMGGVEVDELVLLDIAAEVLDTMEDELYIMGSGTTVAAVMDELQLDNTLLGVDLVRDRELVASDLSAAQLLEQTLDQPVKLVITLIGGQGHILGRGNQQLSSELIKRVTKENIIILATKTKLKALEGRPLIVDSGDPELDRALCGYYRVITGFHDHVMYQVANPDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKU3</accession>
    <name>B1KKU3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327075.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4498"/>
    <dbReference type="EnsemblBacteria" id="ACA88749">
        <property type="protein sequence ID" value="ACA88749"/>
        <property type="gene ID" value="Swoo_4498"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4498"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004585_5_5_6"/>
    <dbReference type="OMA" id="YQDTNRT"/>
    <dbReference type="OrthoDB" id="137860at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005753">
        <property type="entry name" value="DNA_helicase_ATP-dep_UvrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01075">
        <property type="entry name" value="uvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="287"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="721" mass="81687" checksum="2E170D31DE0EA269" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKU8</accession>
    <name>B1KKU8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327080.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4503"/>
    <dbReference type="EnsemblBacteria" id="ACA88754">
        <property type="protein sequence ID" value="ACA88754"/>
        <property type="gene ID" value="Swoo_4503"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4503"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_6_1_6"/>
    <dbReference type="OMA" id="WDEWVAQ"/>
    <dbReference type="OrthoDB" id="1633707at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06150">
        <property type="entry name" value="YjgF_YER057c_UK114_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035709">
        <property type="entry name" value="YoaB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47328">
        <property type="entry name" value="PTHR47328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="12899" checksum="180FC86CE2989DC7" modified="2008-04-29" version="1">MSIERLETATRMSRIVKHNGTIYLCGQVCKDAEQGITEQTSSMLEKVDALLAQAGSDREHILSATIYVKDMSYFAEMNAVWDAWVPEGHAPARACVAAKMAREALLVEISVVAAEKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL06</accession>
    <name>B1KL06_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">coaBC</name>
        <name evidence="7" type="ordered locus">Swoo_4562</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327137.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4562"/>
    <dbReference type="EnsemblBacteria" id="ACA88812">
        <property type="protein sequence ID" value="ACA88812"/>
        <property type="gene ID" value="Swoo_4562"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4562"/>
    <dbReference type="eggNOG" id="COG0452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033319_0_1_6"/>
    <dbReference type="OMA" id="LDMIVAN"/>
    <dbReference type="OrthoDB" id="1346419at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="12"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="191"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="196"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="278"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="310"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="43734" checksum="229918F136199DCD" modified="2008-04-29" version="1">MNQSQNKSQVTKNVLLAIGGGIAAYKSADLIRRLKERGFDVRVVMSQSAKEFITPLTLQALSGYPVASDLLDPAAEAAMGHIELARWADLVVVAPATANLIARINAGMADELITTTCLATEAPVVICPAMNQQMYRNQATQDNLANLTKRGLTIWGPASGSQACGEVGPGRMQEPLEIALQVEQFFAPKLLQGKSILLTAGPTREAIDPVRYISNHSSGKMGFAIAAAAAAMGADVILVAGPVHLPTPSGVKRIDVESTQDMLSAVMQHVDTHDIFIGCAAVADYRIDQVAEDKIKKSAQDMQLALVRNPDILATVASHKPRPFTVGFAAETKDVEHYAKDKLIRKKLDMIAANDVSNPAQGFNTEQNALKVIWANGQQDLPTTDKQILAGQLLTLIADQLALLKDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL51</accession>
    <name>B1KL51_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable queuosine precursor transporter</fullName>
            <shortName evidence="1">Q precursor transporter</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322741.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0091"/>
    <dbReference type="EnsemblBacteria" id="ACA84392">
        <property type="protein sequence ID" value="ACA84392"/>
        <property type="gene ID" value="Swoo_0091"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0091"/>
    <dbReference type="eggNOG" id="COG1738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090905_0_0_6"/>
    <dbReference type="OMA" id="IWLSLFH"/>
    <dbReference type="OrthoDB" id="1462872at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990397">
        <property type="term" value="P:queuosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02088">
        <property type="entry name" value="Q_prec_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003744">
        <property type="entry name" value="YhhQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34300">
        <property type="entry name" value="PTHR34300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02592">
        <property type="entry name" value="Vut_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00697">
        <property type="entry name" value="TIGR00697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="223" mass="24808" checksum="7CBF180829D0A235" modified="2008-04-29" version="1">MLTLTTTQVRRALLLLVGFHISIICASNYLVQLPFQIFGFHTTWGAFSFPFVYLATDLTVRIFGQSPARRIILKAMLPALLISYLMGVLFHQGSFQGLSSLSEFNTFVFRIAFASFAAYLVGQLMDITVFAKLRDTRSWWVAPAASTLIGNLVDTIVFFALAFYASTDAFMAQHWPEIATVDYGFKLIVSLGLFLPAYGVLLKILEQKIVNPSQATGDQQNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLB4</accession>
    <name>B1KLB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating GFA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1551"/>
    <dbReference type="EnsemblBacteria" id="ACA85839">
        <property type="protein sequence ID" value="ACA85839"/>
        <property type="gene ID" value="Swoo_1551"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1551"/>
    <dbReference type="eggNOG" id="COG3791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_7_5_6"/>
    <dbReference type="OMA" id="CSRCGIY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="30"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="16216" checksum="680F5E655F908E9A" modified="2008-04-29" version="1">MTTPHDVVLFMPLGGNMLKQVGETQIQVKHRASCHCGAVELELSLPQGIVNPRRCDCSICRRKGAIVGSVNLDDIRIVKGEEFLKLYQFNTGTAKHYFCSNCGIYTHHQRRSNPQEYGFNIGCLEGVNPFDLGAVVTNDGVNHPADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI6</accession>
    <name>B1KLI6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Flagellar motor switch protein FliM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1625</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FliM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324257.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1625"/>
    <dbReference type="EnsemblBacteria" id="ACA85911">
        <property type="protein sequence ID" value="ACA85911"/>
        <property type="gene ID" value="Swoo_1625"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1625"/>
    <dbReference type="eggNOG" id="COG1868">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052646_1_2_6"/>
    <dbReference type="OMA" id="NPQFTQI"/>
    <dbReference type="OrthoDB" id="1748746at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17908">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001689">
        <property type="entry name" value="Flag_FliM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02154">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002888">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00955">
        <property type="entry name" value="FLGMOTORFLIM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01397">
        <property type="entry name" value="fliM_switch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5 10" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="6 10" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="11">
        <location>
            <begin position="249"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR002888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="342" mass="38954" checksum="FC551F3D26308181" modified="2008-04-29" version="1">MSDLLSQDEIDALLHGVDDVEEEEVEEGGVDARSYDFSSQDRIVRGRMPTLEIVNERFARHLRISMFNMMRRAAEVSINGVQMLKFGEYVHTLFVPTSLNMVRFNPLKGTALITMEARLVFILVDNFFGGDGRFHAKIEGREFTPTERRIVQLLLKIIFEDYKDAWAPVMDVEFDYLDSEVNPAMANIVSPTEVVVISSFHIEVDGGGGDFHITMPYSMIEPIRELLDAGVQSDTQDTDMRWSQALKDEIMDVNVGLDATVVEHQITLKDVMELKQGDIIPVELPEHIILRVEDLPTFRCKLGKARDNLALRVIQKIPRPETAKSELHLITRKAKVREVKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLJ0</accession>
    <name>B1KLJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar biosynthetic protein FliQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1629</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324261.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1629"/>
    <dbReference type="EnsemblBacteria" id="ACA85915">
        <property type="protein sequence ID" value="ACA85915"/>
        <property type="gene ID" value="Swoo_1629"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1629"/>
    <dbReference type="eggNOG" id="COG1987">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164516_2_0_6"/>
    <dbReference type="OMA" id="ALMFLGH"/>
    <dbReference type="OrthoDB" id="1939288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="9857" checksum="BCBC8723300F8B37" modified="2008-04-29" version="1">MSPESLVDIFREALSVIVTIVSLIILPGLVIGLIVAVFQAATSINEQTLSFLPRLLTTLFALMFLGHTLIQTMMEFFFEMVNMIPQVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLR1</accession>
    <name>B1KLR1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3087</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325694.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3087"/>
    <dbReference type="EnsemblBacteria" id="ACA87358">
        <property type="protein sequence ID" value="ACA87358"/>
        <property type="gene ID" value="Swoo_3087"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3087"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_2_2_6"/>
    <dbReference type="OMA" id="AFWTVST"/>
    <dbReference type="OrthoDB" id="1445898at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="27611" checksum="3C943922538C0F41" modified="2008-04-29" version="1">MELLLEPSTWAILAGIGLIAGFIDAVAGGGGLLSIPALLTLGISPHLALGTNKLAACFGSSMAAFTYYRQNLFSPTLWYQTFIATFLGAVSGTFLVYYIDKEWLEKGLPLIIIAIAIYTLVKPNAMGCKDYVPLKKSASGLKQWLLAFPLGFYDGFAGPGAGAFWTISSTNYYRQPLLYSCGLARAMTFVSNLTSLAIFFILGQVNLILGLSMGICMMLGSFIGARSAIKFGVQFIRPVFIIIVLIIAVKLAWSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM03</accession>
    <name>B1KM03_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327207.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4633"/>
    <dbReference type="EnsemblBacteria" id="ACA88883">
        <property type="protein sequence ID" value="ACA88883"/>
        <property type="gene ID" value="Swoo_4633"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4633"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101288_3_1_6"/>
    <dbReference type="OMA" id="WEINSHM"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="97"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="176" mass="19903" checksum="418FF4FB4B34E04E" modified="2008-04-29" version="1">MSYAKTFKELDKSQHDRASFDCGEKELNDFIQTQAAKHMQAGISRTMVLPASVPLPNQKYPICSFYSIAPSSISRDTLPQAMAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIKALEYLWEINSHMRAYSIVVDCLTEQAESFYAKYGFEVLCEINGRVRMFIPMKTVGQLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM04</accession>
    <name>B1KM04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4634</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327208.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4634"/>
    <dbReference type="MEROPS" id="S41.012"/>
    <dbReference type="EnsemblBacteria" id="ACA88884">
        <property type="protein sequence ID" value="ACA88884"/>
        <property type="gene ID" value="Swoo_4634"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4634"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031949_2_0_6"/>
    <dbReference type="OMA" id="KPYGFYP"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766808" evidence="2">
        <location>
            <begin position="21"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="149"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="4">
        <location>
            <begin position="261"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="533" mass="57114" checksum="14108FD2AE5B9A1D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM22</accession>
    <name>B1KM22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88902">
        <property type="protein sequence ID" value="ACA88902"/>
        <property type="gene ID" value="Swoo_4652"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4652"/>
    <dbReference type="HOGENOM" id="CLU_2452947_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="10129" checksum="F3F2F071C3C373B1" modified="2008-04-29" version="1">MLQVPFYLAFAKSDWPAVPCQWMRIIGITRNCARAFIEKNAFSALSVFLSLNTLDIDTILEFKIQKRGLTPLLSIHIPASLLFINKALY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM33</accession>
    <name>CCME_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytochrome c-type biogenesis protein CcmE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytochrome c maturation protein E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Heme chaperone CcmE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ccmE</name>
        <name evidence="1" type="synonym">cycJ</name>
        <name type="ordered locus">Swoo_4663</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CcmE/CycJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327237.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KM33"/>
    <dbReference type="SMR" id="B1KM33"/>
    <dbReference type="STRING" id="392500.Swoo_4663"/>
    <dbReference type="EnsemblBacteria" id="ACA88913">
        <property type="protein sequence ID" value="ACA88913"/>
        <property type="gene ID" value="Swoo_4663"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4663"/>
    <dbReference type="eggNOG" id="COG2332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079503_1_0_6"/>
    <dbReference type="OMA" id="HVEFAVH"/>
    <dbReference type="OrthoDB" id="1724595at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017003">
        <property type="term" value="P:protein-heme linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01959">
        <property type="entry name" value="CcmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004329">
        <property type="entry name" value="CcmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036127">
        <property type="entry name" value="CcmE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34128">
        <property type="entry name" value="PTHR34128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03100">
        <property type="entry name" value="CcmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82093">
        <property type="entry name" value="SSF82093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0735">Signal-anchor</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000189052" description="Cytochrome c-type biogenesis protein CcmE">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="8"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Signal-anchor for type II membrane protein" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="1">
        <location>
            <begin position="30"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01959"/>
        </source>
    </evidence>
    <sequence length="161" mass="17350" checksum="36A8801142F82196" modified="2008-04-29" version="1">MNARRKKRLALATALIGGVAAIASLLLYALNSNLNLFYTPTEIVQGKKDTGVKPEVGQRIRVGGMVTVGSMVRDPNSLHVEFAVHDAAGGEVIVTYDDLLPDLFREGQGIVAQGVLIEGGKLEATEVLAKHDENYMPPEVAEAMGQSHEKLDYNAEQKSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM79</accession>
    <name>B1KM79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322841.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0191"/>
    <dbReference type="EnsemblBacteria" id="ACA84492">
        <property type="protein sequence ID" value="ACA84492"/>
        <property type="gene ID" value="Swoo_0191"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0191"/>
    <dbReference type="eggNOG" id="COG1592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116288_0_0_6"/>
    <dbReference type="OMA" id="PMNPAIT"/>
    <dbReference type="OrthoDB" id="1798264at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765051" evidence="1">
        <location>
            <begin position="24"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="2">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="2">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="138" mass="15022" checksum="1D8BAC3F3679B8A2" modified="2008-04-29" version="1" precursor="true">MKTLLSLILSAFILISAAPLATAHEHSQHKADDQHHQMKVDHACPMHAEVTGKQGDTCPKCGMNLTKVQGSSEQHKNCASCPKHKNHQHKHDKTAHTHACPMNSSITGKEGDTCPKCGMNLEPMQAKADSKSTGHHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMA5</accession>
    <name>B1KMA5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0217</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322867.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0217"/>
    <dbReference type="EnsemblBacteria" id="ACA84518">
        <property type="protein sequence ID" value="ACA84518"/>
        <property type="gene ID" value="Swoo_0217"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0217"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_14_1_6"/>
    <dbReference type="OMA" id="FLCGPFE"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="3"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="266"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="357" mass="39665" checksum="BD5EE252D0402D3A" modified="2008-04-29" version="1">MNNEFYQLNIASLDRSTSDSVAITFDVPQALQSTFRFKPGQYLTLKHDIDGQEIRRCYSISAPVSSHKLEVGIKSIPDGLFSNFANNQLTVGQSLAVLPPTGNFICDLKQHTNICLLAAGSGITPMLSIAESVLENSTESHISLVYSNKQMQSMMFRERLSFLKNRYISRFNFINLFSREDSEVELFNGRLTPEKISALIKAGIVQLDAFDSFFLCGPNEMVDSIRQVLLEKNIDADAIKSELFFAGDISQALNLKRQEEYGERIRQVKLKIDGRKLSIDLISGGKTILDAALDQGADLPFSCKGGVCATCKARVIKGKVEMDLNHSLTDEEIKQGMVLTCQSHPVSDDVEIDFDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB5</accession>
    <name>B1KMB5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylacetate-coenzyme A ligase</fullName>
            <ecNumber evidence="1">6.2.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phenylacetyl-CoA ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-phenylacetate + ATP + CoA = AMP + diphosphate + phenylacetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:20956"/>
            <dbReference type="ChEBI" id="CHEBI:18401"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57390"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Aromatic compound metabolism; phenylacetate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phenylacetyl-CoA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.30" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322877.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0227"/>
    <dbReference type="EnsemblBacteria" id="ACA84528">
        <property type="protein sequence ID" value="ACA84528"/>
        <property type="gene ID" value="Swoo_0227"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0227"/>
    <dbReference type="eggNOG" id="COG1541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035301_1_1_6"/>
    <dbReference type="OMA" id="GVAPHFQ"/>
    <dbReference type="OrthoDB" id="839891at2"/>
    <dbReference type="UniPathway" id="UPA00930"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047475">
        <property type="term" value="F:phenylacetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05913">
        <property type="entry name" value="PaaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028154">
        <property type="entry name" value="AMP-dep_Lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011880">
        <property type="entry name" value="PA_CoA_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14535">
        <property type="entry name" value="AMP-binding_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006444">
        <property type="entry name" value="PaaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02155">
        <property type="entry name" value="PA_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="89"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C_2" evidence="3">
        <location>
            <begin position="342"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="48308" checksum="DD11C65D81AD9E0B" modified="2008-04-29" version="1">MTNESTNNRVGVGLHSIESASIDELRALQFERLKKTLNHAYTNSPAYKRKFDEAGVHPDDFNHLDDLRKFPFTTKQDLRDNYPFGFFAMPMDDIVRIHASSGTTGQPTVVGYTQEDIHTWADIVARSVYAAGGRKKDKVHISYGYGLFTGGLGAHYGAERLGCTVIPMSGGQTAKQVQLIRDFNPDIIMVTPSYMLNIADEIERQGIDPKSLALRCGIFGAEPWTDAMRSNIEQRLGIDAVDIYGLSEVMGPGVAQECIESKDGPTIWEDHFYPEIINPETGEIVEDGEPGELVFTSLTKQAMPIIRYRTRDLTSLLASTSRSMRRMDKITGRSDDMLIIRGVNVFPSQIEEQLLSIEGLSPHYLVEVAKMGHMDYLTVKVERSLDQQCNKEQAKLLESKIKSVIGISSKVVLLEPQTIARSEGKACRVTDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMD4</accession>
    <name>B1KMD4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324278.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1646"/>
    <dbReference type="EnsemblBacteria" id="ACA85932">
        <property type="protein sequence ID" value="ACA85932"/>
        <property type="gene ID" value="Swoo_1646"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1646"/>
    <dbReference type="eggNOG" id="ENOG5032RM7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016608_0_0_6"/>
    <dbReference type="OMA" id="PYGINQR"/>
    <dbReference type="OrthoDB" id="1483195at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="644" mass="70200" checksum="F61250A9EB0A6C0D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN35</accession>
    <name>B1KN35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327309.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4742"/>
    <dbReference type="EnsemblBacteria" id="ACA88992">
        <property type="protein sequence ID" value="ACA88992"/>
        <property type="gene ID" value="Swoo_4742"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4742"/>
    <dbReference type="eggNOG" id="COG4676">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_428879_0_0_6"/>
    <dbReference type="OrthoDB" id="1799195at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="638" mass="69437" checksum="4E32E6AB08BE4024" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN60</accession>
    <name>B1KN60_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0256</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322906.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0256"/>
    <dbReference type="EnsemblBacteria" id="ACA84557">
        <property type="protein sequence ID" value="ACA84557"/>
        <property type="gene ID" value="Swoo_0256"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0256"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_20_6"/>
    <dbReference type="OMA" id="WQGEVWK"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="151"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="307"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="448"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="703" mass="78737" checksum="B51BF2E7E89B4527" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNA8</accession>
    <name>B1KNA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type III restriction protein res subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322954.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0304"/>
    <dbReference type="REBASE" id="17467">
        <property type="entry name" value="SwoAIIP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84605">
        <property type="protein sequence ID" value="ACA84605"/>
        <property type="gene ID" value="Swoo_0304"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0304"/>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015668_0_0_6"/>
    <dbReference type="OMA" id="ELWAKKS"/>
    <dbReference type="OrthoDB" id="13585at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="890" mass="100292" checksum="6D6B67E3B78A025D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB7</accession>
    <name>B1KNB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type IV-A pilus assembly ATPase PilB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322963.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0313"/>
    <dbReference type="EnsemblBacteria" id="ACA84614">
        <property type="protein sequence ID" value="ACA84614"/>
        <property type="gene ID" value="Swoo_0313"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0313"/>
    <dbReference type="eggNOG" id="COG2804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013446_10_3_6"/>
    <dbReference type="OMA" id="NMGVPAF"/>
    <dbReference type="OrthoDB" id="749544at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013374">
        <property type="entry name" value="ATPase_typ4_pilus-assembl_PilB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02538">
        <property type="entry name" value="type_IV_pilB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="4">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="569" mass="62867" checksum="AAA673C30E4FDF46" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNK2</accession>
    <name>RECR_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recR</name>
        <name type="ordered locus">Swoo_1795</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324425.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNK2"/>
    <dbReference type="SMR" id="B1KNK2"/>
    <dbReference type="STRING" id="392500.Swoo_1795"/>
    <dbReference type="EnsemblBacteria" id="ACA86079">
        <property type="protein sequence ID" value="ACA86079"/>
        <property type="gene ID" value="Swoo_1795"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1795"/>
    <dbReference type="eggNOG" id="COG0353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060739_1_2_6"/>
    <dbReference type="OMA" id="DVMAIEN"/>
    <dbReference type="OrthoDB" id="1661836at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_1000089770" description="Recombination protein RecR">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Toprim" evidence="1">
        <location>
            <begin position="81"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <sequence length="199" mass="20964" checksum="F99E932F2F15E562" modified="2008-04-29" version="1">MKFSPLVDELIQSLKCLPGVGPKSAQRMAFQLLERDRKAGQSLASALSSAMSDVGHCQACRTFTEETLCPICASHKRGNSEVICVVETPADVLAIEAGGHFSGRYFVLLGHLSPLDGVGPEELGLSLLEAHLASGEVSELILATNPTVEGDATAHFIADMAKGHQVSVSRIAHGVPVGGELEYVDSTTLALSFNGRLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNN5</accession>
    <name>B1KNN5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_3223</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325829.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3223"/>
    <dbReference type="EnsemblBacteria" id="ACA87493">
        <property type="protein sequence ID" value="ACA87493"/>
        <property type="gene ID" value="Swoo_3223"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3223"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_1_6"/>
    <dbReference type="OMA" id="CFITNSG"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901565">
        <property type="term" value="P:organonitrogen compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01156">
        <property type="entry name" value="IVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034183">
        <property type="entry name" value="IVD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0274">FAD</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="11">
        <location>
            <begin position="14"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="10">
        <location>
            <begin position="129"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="9">
        <location>
            <begin position="236"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="247"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="370"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="163"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="343"/>
            <end position="347"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="372"/>
            <end position="374"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="389" mass="42159" checksum="6101D18FAD2B0445" modified="2008-04-29" version="1">MTQLYSSLNFGLGEDVDMLRDAVQSFAANEIAPIAEKTDRDNAFPNELWPVLGDMGLLGVTVSEEYGGANMGYLAHVVAMEEISRASASIGLSYGAHSNLCVNQINRNGNAEQKAKYLPKLVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRYILNGNKMWITNGPDANTYVIYAKTDLDKGAHGITAFIVDRDSKGFSTAQKLDKLGMRGSNTCELVFEDCEVPEENILGGLNNGVKVLMSGLDYERVVLSGGPLGIMTACMDIVVPYIHEREQFGKSIGQFQLVQGKLADMYTGMNAAKSYIYNVAKSCDRGETTRKDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFNESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ0</accession>
    <name>B1KNZ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327338.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4772"/>
    <dbReference type="EnsemblBacteria" id="ACA89021">
        <property type="protein sequence ID" value="ACA89021"/>
        <property type="gene ID" value="Swoo_4772"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4772"/>
    <dbReference type="eggNOG" id="ENOG5033JYZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1234320_0_0_6"/>
    <dbReference type="OMA" id="RYCSIQG"/>
    <dbReference type="OrthoDB" id="1673772at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="216" mass="24322" checksum="DEDD4AAD631D5ADD" modified="2008-04-29" version="1">MNKKYVTRDSLFKTSAKEYIEQKELDSEQLDRFENLLGGYTEEARPKESNTALGVSRRTSVYMAITASVVMLLMMSLNLYLQQPSKIGLIANEVAMNHIKMKPLELKTEQLPPLRDYFTQLDFSIVNSSIFSQQNNSMLGGRYCSIQGVTAAQIRYQTAAGKKVTLYEVGYDPQIYGVLPDVDKGEKPLYIEVKGISVNLWVEKGLLMAEARDIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ3</accession>
    <name>B1KNZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327341.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4775"/>
    <dbReference type="EnsemblBacteria" id="ACA89024">
        <property type="protein sequence ID" value="ACA89024"/>
        <property type="gene ID" value="Swoo_4775"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4775"/>
    <dbReference type="eggNOG" id="COG3220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064263_0_0_6"/>
    <dbReference type="OMA" id="GQARFRW"/>
    <dbReference type="OrthoDB" id="1602134at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007801">
        <property type="entry name" value="UPF0276"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42194">
        <property type="entry name" value="PTHR42194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05114">
        <property type="entry name" value="DUF692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="32543" checksum="BAE88DC28B4F017A" modified="2008-04-29" version="1">MSDNHLVGAGIGLRLPHVQEILAAGQTGIPWFEVLVDNWLVEGGLNKRMLQEVCERYPIVLHSVGLSLGGLSPLDLDYLKQVKALKRETGAIWYSEHASFSGNNDFKVPDLLPLPYTEEAVDHLSQRIMQVQEFMGERILLENVSTYLSCQFNEMTEGEFIAAVADKADCYLLLDINNAYVTAKNLDQEMQTFMDVIPVERVKQIHLAGFHEKEDFLLDAHNHAVDQKVWQAFEQFIEKNGAIPSMIEWDNDLPPLARLLQEREIAASILASAKPVTQAAAAFRGSYAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP12</accession>
    <name>B1KP12_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="10">ETF-QO</shortName>
            <ecNumber evidence="10">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4794</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H(+) + oxidized [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327360.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4794"/>
    <dbReference type="EnsemblBacteria" id="ACA89043">
        <property type="protein sequence ID" value="ACA89043"/>
        <property type="gene ID" value="Swoo_4794"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4794"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2440">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009667_4_1_6"/>
    <dbReference type="OMA" id="GGGWMYH"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="PTHR10617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="9 10" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="11">
        <location>
            <begin position="509"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA89043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="549" mass="60178" checksum="BC0DDC0148C8B772" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP25</accession>
    <name>B1KP25_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Formate dehydrogenase, gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4807</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the formate dehydrogenase gamma subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327373.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4807"/>
    <dbReference type="EnsemblBacteria" id="ACA89056">
        <property type="protein sequence ID" value="ACA89056"/>
        <property type="gene ID" value="Swoo_4807"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4807"/>
    <dbReference type="eggNOG" id="COG2864">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047957_0_0_6"/>
    <dbReference type="OMA" id="DIVWAKN"/>
    <dbReference type="OrthoDB" id="1612137at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009326">
        <property type="term" value="C:formate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006471">
        <property type="entry name" value="Formate_DH_gsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01583">
        <property type="entry name" value="formate-DH-gamm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766915" evidence="10">
        <location>
            <begin position="25"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="11">
        <location>
            <begin position="112"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA89056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="36010" checksum="9168232C9B2DC067" modified="2008-04-29" version="1" precursor="true">MNNWFKQIGLILVLMFSAIGLAQAGAEQPVATDGQIWSQLQAGATGETTSHGEFHNQPINTYDLRVLELRSDLLAPALMAALFGMIIIFVVFIKINGISKLHGGYSGKLVYRWSKFDVSIHWLGAIPCLLLILTGLTLLAGRFFFQPYIGEGLWAGLVYGAKQVHDFMAIPFMLGWALMVTLWAKNQLPKMYDLKWMMVVGGYINFGPFKGKHPDAGFANAGEKLWFWAFALFGLVISASGMLLLFPNLFEPSRTLSLIALVLHSVAAIIITAFSIVHIFMATVMSEGGMECMVSGYCDETWASQHHNLWFDEIKENGTLKYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP96</accession>
    <name>B1KP96_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0366"/>
    <dbReference type="EnsemblBacteria" id="ACA84666">
        <property type="protein sequence ID" value="ACA84666"/>
        <property type="gene ID" value="Swoo_0366"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0366"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073042_0_0_6"/>
    <dbReference type="OMA" id="TGPEIQV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767267" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="43"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="26634" checksum="35A0500AD4CB1BFE" modified="2008-04-29" version="1" precursor="true">MTKWGVSIKSRSQQVIAALLLSTVATAGVAADNQLSKKEKEAGWQLLFNGKDMSQWRNFKQQGVNPKWVIDQDSIHLSGGGGGDLLTKQAYKNFELTLDWKISRAGNSGIFVLADELGSKIYSHAIEVQILDNQRHADNKIDSHLSGSIYDIQASPPASHRVAGEWNKVRIRMHNNSLSVWQNGILTADLIVGSEKWNSLVAESKFRTWTGFAQTSQGHIGLQDHSDPVWFKNIKLREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPB2</accession>
    <name>B1KPB2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1232 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323031.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84682">
        <property type="protein sequence ID" value="ACA84682"/>
        <property type="gene ID" value="Swoo_0383"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0383"/>
    <dbReference type="eggNOG" id="COG3339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133088_0_1_6"/>
    <dbReference type="OMA" id="PDTPKWA"/>
    <dbReference type="OrthoDB" id="2017850at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010652">
        <property type="entry name" value="DUF1232"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016983">
        <property type="entry name" value="UCP031804"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06803">
        <property type="entry name" value="DUF1232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031804">
        <property type="entry name" value="UCP031804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="DUF1232" evidence="5">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12506" checksum="627AF02629875F27" modified="2008-04-29" version="1">MSDNSDNAATDGYSEEGFWLKVKQFAVKAGREVIDNALCLYYAAKRPDTPKWAKTIIFGALAYFITPLDAIPDLTPMVGFTDDLGALAAALAMVAMYVDDTVKNQAAEKSAAWFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE1</accession>
    <name>B1KPE1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84711">
        <property type="protein sequence ID" value="ACA84711"/>
        <property type="gene ID" value="Swoo_0412"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0412"/>
    <dbReference type="HOGENOM" id="CLU_1204124_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="25890" checksum="0CB6D50137933BB7" modified="2008-04-29" version="1">MNVEEGEKVSDIQKLWEFFLNHSLLVLTTFGLLASTIGYATQYTLLKQFGVNFVNYAELDDFLLAAWKVPASSIYIIFMCLMVGFLYSITVAFKKSDDEFSKLNPEKANQKKNKLGRYGIFFLSILGITFIFILAYSIFKMTIDSQLRVIQGQTSVAIVHLRSGGCIPYKQDTSLSLISATSKFMFFYQQSDISGKIKTIAIPIASISNVEYMNNPKAMLNPEPLTDNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPZ7</accession>
    <name>B1KPZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327427.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4861"/>
    <dbReference type="EnsemblBacteria" id="ACA89110">
        <property type="protein sequence ID" value="ACA89110"/>
        <property type="gene ID" value="Swoo_4861"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4861"/>
    <dbReference type="eggNOG" id="ENOG5032YFA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_637592_0_0_6"/>
    <dbReference type="OMA" id="ILIPRYR"/>
    <dbReference type="OrthoDB" id="683410at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="428" mass="47586" checksum="83B04739C6C3E4FD" modified="2008-04-29" version="1">MSRSSVIKLTINRFDGAVRLWLFDVVCASFFGVALLGLLLLLPIFWFEKFDVIPLMLSMFQVSVSISVAWQLNRLAATEWSILIPRYRGNLLFQAATLLLVSFLICALISLVSGADGSFTQLQLATAAGLIFIYLCLIKVQTYYWSVLLYLFLMSLSSLASQIPTEINIPLFVANGVLAWLLWQKANGNPWHPDARSVYLNAQEMGGVWLPGLKSNPQLVKFELWLHPVNFFMGPLLTILLLAMPVVTLVVAGLSSAIGGDIPALFLYTQFACVACSMVHWSRIHRWRAVESLYMLPGFDGKQGMRDAFNLGQVKLLILLVSMMGLVAAVISLFEPLITIGVWFHLVLSTLFGCGLILGVGSGCKNALQLSLLMLIIICQSVWISTSLGQISDGGEIWLWLSIDIILMVFSFVTLWWGSKKLWDGDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ53</accession>
    <name>B1KQ53_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2357 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327482.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4917"/>
    <dbReference type="EnsemblBacteria" id="ACA89166">
        <property type="protein sequence ID" value="ACA89166"/>
        <property type="gene ID" value="Swoo_4917"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4917"/>
    <dbReference type="eggNOG" id="COG1700">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019820_0_0_6"/>
    <dbReference type="OMA" id="QMHRYRD"/>
    <dbReference type="OrthoDB" id="643928at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018633">
        <property type="entry name" value="DUF2357"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007505">
        <property type="entry name" value="PDDEXK_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09823">
        <property type="entry name" value="DUF2357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04411">
        <property type="entry name" value="PDDEXK_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2357" evidence="1">
        <location>
            <begin position="122"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="780" mass="90432" checksum="7569DAA89DA1433E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE0</accession>
    <name>B1KQE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0497</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323144.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0497"/>
    <dbReference type="EnsemblBacteria" id="ACA84795">
        <property type="protein sequence ID" value="ACA84795"/>
        <property type="gene ID" value="Swoo_0497"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0497"/>
    <dbReference type="eggNOG" id="COG3550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030167_2_1_6"/>
    <dbReference type="OMA" id="SDIPLGM"/>
    <dbReference type="OrthoDB" id="1293681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="4"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="150"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="438" mass="49078" checksum="6CC2818D995EC178" modified="2008-04-29" version="1">MAVLDIYMNGYLVGELTKSTTGSHLFEYAPQWLDTQGSRPISLSMPLRKQVYKGDEVYNFFDNLLPDNIEVRNRIVARHNAQSTQAFDLLSKVGQDSVGALQLVPHGQAPFEVKKIEAKPLSDEALEKVLKGYQSDIPLGMLNDEDDFRISIAGAQEKTALLNLDGQWKLPIKATPTTHIIKLPIGDIQSHSYRIDMSDSVENEFLCMMIVREFGLAVPHCSIIKVGDIKALAVDRFDRKLSSDGQWIMRLPQEDFCQTLNVPPAKKYENHGGPGIEQIMPYLVGSTNADQDRLDFMKSQVLFWLLAATDGHAKNFSLFIDAGGGYRLTPFYDIISMYPVIGGKGLNIRDAKLAMGLKASKGKKYSIAQIFPRHFIQTAKAVGFDTEVMAAILIEIEDRVDEVIDKVKAQLPEDFPSHIRDSILDGLKERSQRLKDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQU8</accession>
    <name>B1KQU8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(4)-acetylcytidine amidohydrolase</fullName>
            <shortName evidence="1">ac4C amidohydrolase</shortName>
            <ecNumber evidence="1">3.5.1.135</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N(4)-acetyl-2'-deoxycytidine = 2'-deoxycytidine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:62936"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:146133"/>
            <dbReference type="EC" id="3.5.1.135"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N(4)-acetylcytidine = acetate + cytidine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:62932"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:70989"/>
            <dbReference type="EC" id="3.5.1.135"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N(4)-acetylcytosine = acetate + cytosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:62940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16040"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:146134"/>
            <dbReference type="EC" id="3.5.1.135"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the N(4)-acetylcytidine amidohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.135" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3436"/>
    <dbReference type="EnsemblBacteria" id="ACA87704">
        <property type="protein sequence ID" value="ACA87704"/>
        <property type="gene ID" value="Swoo_3436"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3436"/>
    <dbReference type="eggNOG" id="COG3097">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152586_0_0_6"/>
    <dbReference type="OMA" id="HARQENM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00684">
        <property type="entry name" value="ac4C_amidohydr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008314">
        <property type="entry name" value="AC4CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007374">
        <property type="entry name" value="ASCH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38088">
        <property type="entry name" value="PTHR38088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04266">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029143">
        <property type="entry name" value="UCP029143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01022">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASCH" evidence="2">
        <location>
            <begin position="16"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12939" checksum="5A21E88BBA97CE8F" modified="2008-04-29" version="1">MSSTVDLKMKAAPTKITFFEFLTPFVVSGKKTITIRDESECHYVPGTQVEVFTLETDIKVCDIEILSVEPLQFSEINEFHAEQEYLPLPKLKEIISSVYPDTEQLYLISYKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR42</accession>
    <name>B1KR42_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323207.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0563"/>
    <dbReference type="EnsemblBacteria" id="ACA84859">
        <property type="protein sequence ID" value="ACA84859"/>
        <property type="gene ID" value="Swoo_0563"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0563"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028452_2_2_6"/>
    <dbReference type="OMA" id="CTSVMWG"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="7"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="425" mass="46019" checksum="98D09B9585664124" modified="2008-04-29" version="1" precursor="true">MNKNKLILALVLLTFFVVSFITNILGPLFPSLIADFNLSLALAGFLPFSFFAAYGVMSIPSGMLVDKFSEKPVLFLAFLMAALGSLLFGISPNFYMAMLSLFLIGTGMAMLQVAINPLLRVVGGEEHFAFYSVSAQLLFGAAGALSPLVYSKVVLAIDEPNTSSAMVSTLQALVPANMTWVSMYWIFALISLMMLMLITLLKFPKVERNEAESIGAVKVYVSLFKDKKIVLFFLAIAAYVGTEQGVANFISIFLQQQHGLDPVTQGTAVLSQFWLMLTLGCVLGLILVKFLDSRLVLKLFSVSAIISLTAGLFGSKEVALMAFPMVGFFLSVMWSVIFSLALNSVPKHHGSVAGILCTGIIGGGLASPMVGAIADISGDLRLGMVVVYITLFYILSVGFWAKPLINNKTINLFKNRKEETIQTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR90</accession>
    <name>B1KR90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0611</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Cilium membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BBS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323255.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0611"/>
    <dbReference type="EnsemblBacteria" id="ACA84907">
        <property type="protein sequence ID" value="ACA84907"/>
        <property type="gene ID" value="Swoo_0611"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0611"/>
    <dbReference type="eggNOG" id="COG5010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090002_0_0_6"/>
    <dbReference type="OMA" id="YLRPISH"/>
    <dbReference type="OrthoDB" id="1747400at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028786">
        <property type="entry name" value="BBS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44186">
        <property type="entry name" value="PTHR44186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764781" evidence="8">
        <location>
            <begin position="21"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="124"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="26398" checksum="AACBDB3A0CED6039" modified="2008-04-29" version="1" precursor="true">MLRYHIIPLLLLLTMAGCSTTPVSPEVSAKDLIAVGNHAGLIQHYKRELTKKPGSTKVMLKLAQSYYDNGDVESASFYVEQLKKQDFQQPSLYFLSGNIAADSGLFELAVSDYQTAASNGYQGSQLYINLGIAFTNSGQYQAALEAFNQARLMGHDDITVKNNLAVLYLAQGEYLRAVELLTPVYRQHSDEKKLAFNLAISLFKVGDYREAHRLLSDDYSDEQISALFHSLRQGEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRC9</accession>
    <name>B1KRC9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012155714.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2052"/>
    <dbReference type="EnsemblBacteria" id="ACA86336">
        <property type="protein sequence ID" value="ACA86336"/>
        <property type="gene ID" value="Swoo_2052"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2052"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117621_6_1_6"/>
    <dbReference type="OMA" id="FICKDQG"/>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="68" mass="7493" checksum="D854E5CCCE8979E3" modified="2008-04-29" version="1">MSQVTGVVKWFNSDKGFGFIEQESGPDVFVHFRAINSDGFKTLDEGQKVQFTVTQGQKGPQAENVTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD0</accession>
    <name>B1KRD0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2053</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324682.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2053"/>
    <dbReference type="EnsemblBacteria" id="ACA86337">
        <property type="protein sequence ID" value="ACA86337"/>
        <property type="gene ID" value="Swoo_2053"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2053"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="ASHNMAE"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="32219" checksum="EE976ED25EC0666E" modified="2008-04-29" version="1">MSLIKCEQLSKSYGSKLALNSVSIELSSGSPIALVGPNGAGKTTLFSLLCGYLLPSSGSVTILGEKPSSKALLGKVSSLPQDATLDPNLNLITQFTLFGTLQGLTAKAAKDEGLRVLSLVGLSDVSEQKPQSLSHGMGKRASIAQALIGSPQLVLLDEPTAGLDPANAKVIRDLVKTLSTDITFVISSHNLDELEKLCDQVLYLDQGQLGQSVSIQENLTDEYITVSMQSCDKTQLISEISAINGVNSVTQKQEDEFLIHYSANDVIELEVQLFQLFSQNNWRYRAILKGRSLEDKLFS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG4</accession>
    <name>HIS4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="1">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisA</name>
        <name type="ordered locus">Swoo_2087</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324716.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRG4"/>
    <dbReference type="SMR" id="B1KRG4"/>
    <dbReference type="STRING" id="392500.Swoo_2087"/>
    <dbReference type="EnsemblBacteria" id="ACA86371">
        <property type="protein sequence ID" value="ACA86371"/>
        <property type="gene ID" value="Swoo_2087"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2087"/>
    <dbReference type="eggNOG" id="COG0106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_1_2_6"/>
    <dbReference type="OMA" id="EWLHLVD"/>
    <dbReference type="OrthoDB" id="794219at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000190558" description="1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <sequence length="245" mass="26414" checksum="74BAEEF67C24FECE" modified="2008-04-29" version="1">MIIPAIDLIEGQVVRLYQGDYKQKTTFDLSPLSQLKSYQDQGASWLHIVDLTGAKDPDKRQTNLIADLVDGLDANIQVGGGIRSEAQVIELLDIGVKRVVIGSLAVKETALVQSWFEKYGAEAICLALDVNIDEQGEKIVAVSGWQSGGGKTLESLVEAFKPYGLKHALVTDISRDGTLQGANTQLYREIASSYPQIKWQASGGIASLDDVAAVRDSGANGIIIGKALLIENFNVEQAITCWPNS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ3</accession>
    <name>FADB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fatty acid oxidation complex subunit alpha</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase</fullName>
                <ecNumber evidence="1">4.2.1.17</ecNumber>
                <ecNumber evidence="1">5.1.2.3</ecNumber>
                <ecNumber evidence="1">5.3.3.8</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">3-hydroxyacyl-CoA dehydrogenase</fullName>
                <ecNumber evidence="1">1.1.1.35</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">fadB</name>
        <name type="ordered locus">Swoo_0021</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:16105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:20724"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58521"/>
            <dbReference type="ChEBI" id="CHEBI:137480"/>
            <dbReference type="EC" id="4.2.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(3S)-3-hydroxybutanoyl-CoA = (3R)-3-hydroxybutanoyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:21760"/>
            <dbReference type="ChEBI" id="CHEBI:57315"/>
            <dbReference type="ChEBI" id="CHEBI:57316"/>
            <dbReference type="EC" id="5.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:45900"/>
            <dbReference type="ChEBI" id="CHEBI:85097"/>
            <dbReference type="ChEBI" id="CHEBI:85489"/>
            <dbReference type="EC" id="5.3.3.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:45228"/>
            <dbReference type="ChEBI" id="CHEBI:58521"/>
            <dbReference type="ChEBI" id="CHEBI:85097"/>
            <dbReference type="EC" id="5.3.3.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="1"/>
    <dbReference type="EC" id="5.1.2.3" evidence="1"/>
    <dbReference type="EC" id="5.3.3.8" evidence="1"/>
    <dbReference type="EC" id="1.1.1.35" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322671.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCZ3"/>
    <dbReference type="SMR" id="B1KCZ3"/>
    <dbReference type="STRING" id="392500.Swoo_0021"/>
    <dbReference type="EnsemblBacteria" id="ACA84322">
        <property type="protein sequence ID" value="ACA84322"/>
        <property type="gene ID" value="Swoo_0021"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0021"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_16_3_6"/>
    <dbReference type="OMA" id="TGAGWPF"/>
    <dbReference type="OrthoDB" id="977512at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036125">
        <property type="term" value="C:fatty acid beta-oxidation multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008692">
        <property type="term" value="F:3-hydroxybutyryl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01621">
        <property type="entry name" value="FadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012799">
        <property type="entry name" value="FadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02437">
        <property type="entry name" value="FadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0276">Fatty acid metabolism</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0442">Lipid degradation</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000186055" description="Fatty acid oxidation complex subunit alpha">
        <location>
            <begin position="1"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Enoyl-CoA hydratase/isomerase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-hydroxyacyl-CoA dehydrogenase" evidence="1">
        <location>
            <begin position="311"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="active site" description="For 3-hydroxyacyl-CoA dehydrogenase activity" evidence="1">
        <location>
            <position position="450"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="400"/>
            <end position="402"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01621"/>
        </source>
    </evidence>
    <sequence length="716" mass="76934" checksum="1338DB146E80536A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD35</accession>
    <name>B1KD35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326203.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3606"/>
    <dbReference type="EnsemblBacteria" id="ACA87870">
        <property type="protein sequence ID" value="ACA87870"/>
        <property type="gene ID" value="Swoo_3606"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3606"/>
    <dbReference type="HOGENOM" id="CLU_2901771_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="62" mass="7204" checksum="BC72FBFDBA8D0C48" modified="2008-04-29" version="1">MNKRKSIAFIPVGLREQNLILQQQVKSLEAELMKAKKQSLVLARSEQLLLTEDELKMIYAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA2</accession>
    <name>B1KDA2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326270.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3675"/>
    <dbReference type="EnsemblBacteria" id="ACA87937">
        <property type="protein sequence ID" value="ACA87937"/>
        <property type="gene ID" value="Swoo_3675"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3675"/>
    <dbReference type="eggNOG" id="COG5505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034724_1_0_6"/>
    <dbReference type="OMA" id="ATIGMKM"/>
    <dbReference type="OrthoDB" id="1089532at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008537">
        <property type="entry name" value="DUF819"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34289">
        <property type="entry name" value="PTHR34289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05684">
        <property type="entry name" value="DUF819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="417" mass="44645" checksum="83045D171976B340" modified="2008-04-29" version="1">MSSTALVTNDATGLGILALVLGFVFYTSHSKHPFWTKFYTFIPALLMCYFLPSLLNTFNIIDGHTSQLYFVASRYLLPACLVLLILSVDLKAIMSLGPKAIIMFLTGTVGIVIGGPIALLIVSAIHPEILGVQGPEAVWRGMTTLAGSWIGGGANQAAMKEIYEAGGDIFSIMVTVDVIVANIWMAVLLFMASKAKQIDAKTGADTSALEALKDKVEKYHAENARIPSLNDLMMIVAVGFGVTGLAHVVADFLGPFFEANYPWTRDYSLTSKFFWLIVTVTTIGLAMSFSPVRHLEAAGASKVASAFLYILVATIGLHMDVSKLFDAENLWYFAIGIIWMLVHASFMLIVAKLIKAPLFYMAVGSQANVGGAASAPVVAAAFHPALAPVGVLLAVLGYAVGTYMAWMCGQILQIVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDE4</accession>
    <name>B1KDE4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)H quinone oxidoreductase, PIG3 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0649</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323292.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0649"/>
    <dbReference type="EnsemblBacteria" id="ACA84945">
        <property type="protein sequence ID" value="ACA84945"/>
        <property type="gene ID" value="Swoo_0649"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0649"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_6"/>
    <dbReference type="OMA" id="VWSNVFM"/>
    <dbReference type="OrthoDB" id="1027479at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="19"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="339" mass="36539" checksum="48A096DA64503321" modified="2008-04-29" version="1">MSAHSLPQNYLHVTFDEPGAPDVLHLIRSQLPKIEEDQVLIRVHVAGVNGPDLAQRKGVYPAPTGASSILGLEVAGEVVALGSKVTRWQLGERVCALVPGGGYGEYVATYADHCLPIPHGWRDSDAAAIVETFFTVWGNLFMRAGLKVGETVLIHGGSGGVGSAAVVLAKAFGAKVITTSGSNEKCEHCVTLGAELALNYRSDFVTPVMEHTQGRGVDVVFDMAGGDFINQNLKALAMDGRMVSVAMQRGATAEVDIFRIMAKRIRWTGSTLRPQSVGAKAEITTQLLERVWPLLDCELESSTQLKPHVFAEFPLYECAKAHTLMEAGEHRGKLVLRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG3</accession>
    <name>B1KDG3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphoribulokinase</fullName>
            <ecNumber evidence="3 4">2.7.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0668</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the phosphoribulokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.19" evidence="3 4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323311.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0668"/>
    <dbReference type="EnsemblBacteria" id="ACA84964">
        <property type="protein sequence ID" value="ACA84964"/>
        <property type="gene ID" value="Swoo_0668"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0668"/>
    <dbReference type="eggNOG" id="COG3954">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962223_0_0_6"/>
    <dbReference type="OMA" id="TDILFYE"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008974">
        <property type="term" value="F:phosphoribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006082">
        <property type="entry name" value="PRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00478">
        <property type="entry name" value="PHRIBLKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00567">
        <property type="entry name" value="PHOSPHORIBULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="5">
        <location>
            <begin position="7"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="295" mass="33347" checksum="EFE422ED05508791" modified="2008-04-29" version="1">MSAKHPIIAVTGSSGAGTTTTTRAFKHIFRQLGINAATVEGDSFHHFTRPEMELKIRQAQTDNKNISYFGPEANDFDKLEQCFSDYSATGQGETRSYLHTFDEAVPFNQMPGTFTQWHSLPENTDMLYYEGLHGGVKTDSCNVAEHVDLLIGMVPIVNLEWIQKIIRDTSDRGHSREKVMGSIVRSMDDYINHMTPQFSRTHINFQRVPTVDTSNPFSAKSIPSLDESFVVIRFRGIKNVDFPYYLKMIDGSFMSRINTLVVPGGKMSLAMELILTPLIRDLLEKRQQLLSLDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG5</accession>
    <name>B1KDG5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0670"/>
    <dbReference type="ESTHER" id="shewm-b1kdg5">
        <property type="family name" value="abh_upf0017"/>
    </dbReference>
    <dbReference type="MEROPS" id="S33.A46"/>
    <dbReference type="EnsemblBacteria" id="ACA84966">
        <property type="protein sequence ID" value="ACA84966"/>
        <property type="gene ID" value="Swoo_0670"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0670"/>
    <dbReference type="eggNOG" id="COG0429">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032487_0_0_6"/>
    <dbReference type="OMA" id="RNDPFVP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000952">
        <property type="entry name" value="AB_hydrolase_4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01133">
        <property type="entry name" value="UPF0017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="59"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="36309" checksum="224558105541D9C0" modified="2008-04-29" version="1">MMTNNFSPPWWARNPHIQTILPLLTKVDRPALRRERFELNDGDFIDLDWLGSPKKDEAILVIIHGLEGSAESHYVRRLLNDCHQRGLCAVVHHHRSCSGVTNRLARSYHSGDTQDLQDNLQHLQQRFPSSDLLAVGYSLGGNVLTKYLGEYGEQSLLKRGAVISAPLKLSACAKRLEKGFSKLYQSYLIKQLQQKVTDKVKDDSLRDAMPVSLEQIKQLDTFYAFDHRVTAPLHGFSGVDDYYQRASGIDFLASISKPTLVLHAADDPFMTAEVIPAKDNVSPHVTYELHGQGGHVGFINGGTPFKPKYYLEQRILNFLLVSG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-11-16" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM9</accession>
    <name>ZAPC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division protein ZapC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">zapC</name>
        <name type="ordered locus">Swoo_2142</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts directly with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZapC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDM9"/>
    <dbReference type="SMR" id="B1KDM9"/>
    <dbReference type="STRING" id="392500.Swoo_2142"/>
    <dbReference type="EnsemblBacteria" id="ACA86426">
        <property type="protein sequence ID" value="ACA86426"/>
        <property type="gene ID" value="Swoo_2142"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2142"/>
    <dbReference type="eggNOG" id="ENOG502Z8AH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128248_0_0_6"/>
    <dbReference type="OMA" id="IKVMNDR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00906">
        <property type="entry name" value="ZapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009809">
        <property type="entry name" value="ZapC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07126">
        <property type="entry name" value="ZapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010252">
        <property type="entry name" value="ZapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0717">Septation</keyword>
    <feature type="chain" id="PRO_0000413789" description="Cell division protein ZapC">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00906"/>
        </source>
    </evidence>
    <sequence length="181" mass="20487" checksum="6865E85801FB1B8E" modified="2008-04-29" version="1">MVEIMLLMPKKDWQWRYSDTYGVLSVSLGSEMEFLTPYKSKSLIPDALSELEFSVEHAKFYIDFIELLSKSLTISDAMKVQLALNGTAAHFLLKPQMPKSWFFDTSSMCVYSELGKVFQLKCRGAIAQVLVVETSIQASLVMLLSNELPLNDNKSLMQFECIKVMHDRLHPLKVSRAIAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE15</accession>
    <name>B1KE15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326349.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88017">
        <property type="protein sequence ID" value="ACA88017"/>
        <property type="gene ID" value="Swoo_3758"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3758"/>
    <dbReference type="eggNOG" id="ENOG5031GZ3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2636067_0_0_6"/>
    <dbReference type="OMA" id="CNDCHDM"/>
    <dbReference type="OrthoDB" id="2013725at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766982" evidence="1">
        <location>
            <begin position="20"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="76" mass="8058" checksum="FFE96E38AF73CAAB" modified="2008-04-29" version="1" precursor="true">MKYLTLLAAALVFAGSAAAVDCTDCHEPIDQATHVEAEATLGTCNDCHGFSDAHEMDMELHEATLTMAECADCHGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE49</accession>
    <name>B1KE49_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323382.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0740"/>
    <dbReference type="EnsemblBacteria" id="ACA85035">
        <property type="protein sequence ID" value="ACA85035"/>
        <property type="gene ID" value="Swoo_0740"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0740"/>
    <dbReference type="eggNOG" id="ENOG502ZDRV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1255247_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="24747" checksum="F33C820437CCBEC4" modified="2008-04-29" version="1">MNYSALSKNAKIHFNDKYLPDRLPLATKTLLFIRAFGFILTIPLVSSLFMAVRLDGTEQNLFISASLLFTLTVITLLVTKHQLVLDTLNTQAYLELRTFGIKLKQWKSKSLAKTEITLSPSVHKESSYQIIIEGQHFVIGDLAETEQALRFISSHFQLPAFEQVSQYPEIVPLGELKISSDAQAPSKPIEPLWNSTAWLKLLLPLPVFITLGFVLKLFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA4</accession>
    <name>B1KEA4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0795"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85090">
        <property type="protein sequence ID" value="ACA85090"/>
        <property type="gene ID" value="Swoo_0795"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0795"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068408_0_0_6"/>
    <dbReference type="OMA" id="YQEHHYS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="31"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="165"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="39876" checksum="570D48069F735288" modified="2008-04-29" version="1">MRPRVLHLIDDCKLGGVNLALKSLCESRLAEDFEFSITHIDLATHRIKRFEADIIVLHTSSSWRKLPGFISLCFKNRGTPLLLQEHHYCEGFVAHELPNKWRFFLMLKLSYTLMDRVLAVSVAQAKWLLDNRLVNADKLVVLKQARPVNTLLSLPEKALSFPIQLAAYGRFHKQKGFDLLLKAMEKLPSEKVELRLAGSGEMSPLLDSMAATLENVTLIGEIEDVPLFLSSCDAVVIPSRWEPFGLICQESIAAGKMIVTTSVDGLSEQLAELLATRGDEELSVLLTEQSVNGLVDALECLISQAEHKLAVEKVRCLSNLTYEDRCIAAKCWPTLVETWRELLFSEQHRAKRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEP3</accession>
    <name>B1KEP3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamyl-Q tRNA(Asp) synthetase</fullName>
            <shortName evidence="5">Glu-Q-RSs</shortName>
            <ecNumber evidence="5">6.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gluQ</name>
        <name evidence="8" type="ordered locus">Swoo_3799</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3799"/>
    <dbReference type="EnsemblBacteria" id="ACA88058">
        <property type="protein sequence ID" value="ACA88058"/>
        <property type="gene ID" value="Swoo_3799"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3799"/>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015768_0_1_6"/>
    <dbReference type="OMA" id="WLLRMED"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01428">
        <property type="entry name" value="Glu_Q_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022380">
        <property type="entry name" value="Glu-Q_tRNA(Asp)_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03838">
        <property type="entry name" value="queuosine_YadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="7">
        <location>
            <begin position="19"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glutamate binding" evidence="5">
        <location>
            <begin position="19"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="5">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="5">
        <location>
            <begin position="238"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="33030" checksum="AC90F56ECDC36E25" modified="2008-04-29" version="1">MNQDSAITPTRTQSDYIGRFAPSPSGPLHFGSLVAALGSYLRARSLGGKWLVRIEDIDPPREVAGAADMILQTLSAYGLNWDGDILYQSQRLDTYQAKIDKLLSQNQAYYCQCTRKQIQAMGGSYDGRCGQLEIPHTHGAIRIRNTAGVKRFQDLHMGDVCLDSDFATEDFIIKRSDGLYAYQLAVVMDDAYQGVTEVVRGCDLLTPTCRQISLNQQFSYQSPLWLHLPLVCDAPGMKLSKQNHAQAIDTDKPQASLNAALTFLGQQAVTPQNDIRAMLAEAVAQFDLSEIPKQAEIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV7</accession>
    <name>B1KEV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0813"/>
    <dbReference type="EnsemblBacteria" id="ACA85108">
        <property type="protein sequence ID" value="ACA85108"/>
        <property type="gene ID" value="Swoo_0813"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0813"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_6"/>
    <dbReference type="OMA" id="GDHTSYV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="PTHR43521"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="22"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="482" mass="51712" checksum="3E2B0DDCE1C9B9DF" modified="2008-04-29" version="1">MTFSAEKSLYINGEWHTGIGTKANINPSDISESLGEFSQASKQQVVDAIEAARGAQPQWEHTPLEKKQSVLQAIGDELIARCDELGKLLASEEGKPFAEGRGEIYRAGQFFQYFAAEVLRQMGDLAQSVRPGVSVEVTREALGVVAVISPWNFPTATAAWKIAPALAFGNSVIWKPANLTPASAVALTEIIHRQGLPAGTFNLVLGSGAEVGNTLIHSPDIDGVSFTGSVETGRKVATATAANFVRCQLEMGSKNALVIADDADIDIAVEATIMGSFSGAGQKCTASSRLVVFDSVHDAYVDALIKRMSGLKVGHALSEGVFMGPVVDKNQLDANFDWLEKAKAEGASVGFGGEKLTLEHDGYYMSPTLLLETDNSWSVNQEEVFAPMAGIIKVKDLDEAIATVNDTRFGLTGGIITQSLRNSAVFKQQAQTGCVMVNLPTAGTDYHVPFGGRKESSFGPREQGQYAKEFYTVIKTTYQRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX3</accession>
    <name>B1KEX3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0829</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323471.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0829"/>
    <dbReference type="EnsemblBacteria" id="ACA85124">
        <property type="protein sequence ID" value="ACA85124"/>
        <property type="gene ID" value="Swoo_0829"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0829"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007176_0_0_6"/>
    <dbReference type="OMA" id="LVMFGPK"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="491"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="731"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="883"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="11">
        <location>
            <begin position="1056"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1013"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="785"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="932"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="5">
        <location>
            <position position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1240" mass="140137" checksum="5E8B890A896614E0" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF82</accession>
    <name>B1KF82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Gamma-butyrobetaine dioxygenase</fullName>
            <ecNumber evidence="9">1.14.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2344</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.1" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324965.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2344"/>
    <dbReference type="EnsemblBacteria" id="ACA86623">
        <property type="protein sequence ID" value="ACA86623"/>
        <property type="gene ID" value="Swoo_2344"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2344"/>
    <dbReference type="eggNOG" id="COG2175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021859_2_2_6"/>
    <dbReference type="OMA" id="EEKVCIQ"/>
    <dbReference type="OrthoDB" id="819440at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008336">
        <property type="term" value="F:gamma-butyrobetaine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBBH-like_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="TauD" evidence="7">
        <location>
            <begin position="113"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="371" mass="42183" checksum="A843446E48C6077D" modified="2008-04-29" version="1">MFIHRCERVGESLSIQFSNNNEANFSLFWLRDHSTDPSSLNPSTLQRDVETFSLPAVPGLKQFQVINNGAQLQIQWLDGDRVSEFDAHFLFNMACTPVDEPPYQLWASELQEQVPDFDFEQVTANDAAFLPVLESMEQYGLVTFSGMPSNMEATKKLLNQVGYIRDTVFGSLWDFSNNGAHSDSAYTSVGIGLHTDSTYTIDPPGLQLLHCLAFDGEGAFNQFADGFKVAQTIKSEDPAAYETLKRIKVPAHYIEPGIQLRGQHEVVREDINGLFEQICFNNFDRSPFMLSTSEQKAFYHAYGLFQRLINDPKFQVSFQLQPGRAVWFDNWRVLHARSAFSGFRHLAGGYTNREDYISKKLTLRGKTPWQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF94</accession>
    <name>B1KF94_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324977.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2356"/>
    <dbReference type="EnsemblBacteria" id="ACA86635">
        <property type="protein sequence ID" value="ACA86635"/>
        <property type="gene ID" value="Swoo_2356"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2356"/>
    <dbReference type="eggNOG" id="ENOG5033SWB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091612_0_0_6"/>
    <dbReference type="OMA" id="DAFAIAW"/>
    <dbReference type="OrthoDB" id="1411229at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22844" checksum="97768BFF2A5CC239" modified="2008-04-29" version="1">MLCDTKITYINRSLNKDMPKIFIFSANELPSFNALQNGIAWKVIESIGQDSMSTFTYPVKTEIFATWEQGSNQTKSLTCLPGKRYTVTEKSSGIVLIENGNAVKGDEIELTNEIKVQNGVSAYLSKNDKVLISKKIVAYGQKASFKLKPKLYWGIASEIQTSHAISSAVLDSDSFFEQNLENVSAAKVVLTGNAKEGYSFFIEEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFB7</accession>
    <name>B1KFB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325000.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2379"/>
    <dbReference type="EnsemblBacteria" id="ACA86658">
        <property type="protein sequence ID" value="ACA86658"/>
        <property type="gene ID" value="Swoo_2379"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2379"/>
    <dbReference type="eggNOG" id="ENOG5034BXX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_891084_0_0_6"/>
    <dbReference type="OMA" id="HITHEIM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764795" evidence="1">
        <location>
            <begin position="23"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="312" mass="35532" checksum="8688C4F19B0EF4DE" modified="2008-04-29" version="1" precursor="true">MQIIKRVLFVLLLLSIWPIANAEVESNITLSADDISPSDVYVRARVIEQQLLTFDPEGTRFTKTQTPPAYSVENAQPREVFFLAKSLNFSAKKLSLNHTNKKLGRSFAIHVYRNQPLHVYRVLNEALKSIQATQNTLSIVEFKENIPKVQSSPTQVYNKILRNNRLLSILNQDKIQPQDVIKVVDHCYVLSQLLFEKPSATQASAIAEDIPQYKTPTDVFAHLVKTLKMLKRYTESNFGLLSMEITASKIEREIEPSDVLDLAMTLNAQLTYLAYQQKIKVPITNIDRQGVSPSLVFHIVSKIQRTLEQEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE6</accession>
    <name>B1KFE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Succinic semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3863</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326451.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3863"/>
    <dbReference type="EnsemblBacteria" id="ACA88121">
        <property type="protein sequence ID" value="ACA88121"/>
        <property type="gene ID" value="Swoo_3863"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3863"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_5_1_6"/>
    <dbReference type="OMA" id="SYFEWFA"/>
    <dbReference type="OrthoDB" id="384611at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009013">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="20"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="485" mass="51070" checksum="DBFFABEF7985C051" modified="2008-04-29" version="1">MQAVNDTGLVKLSSYIDGSWSDGEQKFDVTNPANGKVIAQVHNAGVDETELAVIAAKRALPTWSKKSANERSAILRTWFNLMMAAQDDLGRILTLEQGKPLAEAKGEIAYGAAFIEWFAEEGKRVYGDTIPAPSGDKRIVVIKQPVGVVASITPWNFPNAMIARKAAAALAAGCTFVVRPSPSTPLSALAMAELAERAGVPAGVFNVVVGEDSVGMGKVLTQHPDVAKFTFTGSTAVGKILMTQTATTVKKVSMELGGNAPFIVFDDADLDAAVQGALISKYRNAGQTCVCTNRILVQKGVAKAFTDKFVTAVEALKMGDGLEAGVNVGPMISSEAVAGVQALVDKTVEQGGVVIKGGKQSSDAGSFYEPTIVANVTNDMALASNEIFGPVTPIITFDTEAEAIEIANDTEYGLAAYFYSRDIGRVWRVGEGLEYGMVGVNEGIISNAAAPFGGVKQSGNGREGSKYGLDDYLEIKYLCMGGIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFK5</accession>
    <name>B1KFK5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3922"/>
    <dbReference type="EnsemblBacteria" id="ACA88180">
        <property type="protein sequence ID" value="ACA88180"/>
        <property type="gene ID" value="Swoo_3922"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3922"/>
    <dbReference type="HOGENOM" id="CLU_2095208_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764810" evidence="1">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="116" mass="12662" checksum="C68D075493A50855" modified="2008-04-29" version="1" precursor="true">MNKQMLCPLLVMFLGGCQANHLVYVQETSFGLTIAASTEGSNKMSLGYDRDIYAIVPKKTDETDAMSLFSVNKVKVKGLDDMEVSEFVASGDAAEELAKSANSIDKLREKVYGDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM5</accession>
    <name>B1KFM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326530.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88200">
        <property type="protein sequence ID" value="ACA88200"/>
        <property type="gene ID" value="Swoo_3943"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3943"/>
    <dbReference type="HOGENOM" id="CLU_675969_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764824" evidence="1">
        <location>
            <begin position="30"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="407" mass="44599" checksum="27FED45CFCC206AE" modified="2008-04-29" version="1" precursor="true">MFTPTKLLRQLAIFSITLTLVGCSTTSIANDKQWTLDAAEINTSTLNSTIEEAIAYLKIAENKNSIATISLPAGEFNLSSNQNEPGTLVFSGLETGNNGKLLFKGKGRSKTTLVFSDFEQIAVYGKMTQGLTLQGLHFTREHYSATQGEVVSTSPGEIIIKIHKGFPKPDFLWRYHDMGHYLKRATNSQSNPKIIQQANKQVKYGYRSGSAYPPEHVKGLQWRFHLANANQDLADNGYTRGSYVAIKAKKSAFPYSFKGGERLTMDNIKWTHSTRGIIRGTKDKTGNQVAIKDITISNCRMVRAAPIFDQTPILSASGGGIQLNQPNDLPATNILVRNCILDSSGDDNIALFNVDGVKLENITSKNAFARSILITDKAKNVCGTNIKVINGVIENDKHQAVTIPACP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY4</accession>
    <name>B1KFY4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bax protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325033.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2413"/>
    <dbReference type="CAZy" id="GH73">
        <property type="family name" value="Glycoside Hydrolase Family 73"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86691">
        <property type="protein sequence ID" value="ACA86691"/>
        <property type="gene ID" value="Swoo_2413"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2413"/>
    <dbReference type="eggNOG" id="COG2992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061344_1_0_6"/>
    <dbReference type="OMA" id="NLFGQWC"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="1">
        <location>
            <begin position="128"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="275" mass="31427" checksum="9ACA9BD56A21DEC9" modified="2008-04-29" version="1" precursor="true">MKTGRVGKLTVSVSIVILAFIVLKLNFIDSEEKQIDQLGAIIENQQHLSLIPDFASIPLVTDKKQAFFDYLRPWVRLQNGIIQDERLFLQRSLQHLNDGLALTNAEYYRIEEIANKYQYSSRAYNTETLKELLVRTDIIPESMVLIQAANETGWGSSRFAREGLNFFGQWCFKKGCGLVPQSRTAGMSHEVAVFKSVEDSVASYMRNLNSNAAYSLLRSIRADMRAQDKEPTADELVYGLVNYSERQEAYIDELLEMLRHNQQYLVGNNEEKPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG32</accession>
    <name>B1KG32_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MbcT/ParT/Res family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325081.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2462"/>
    <dbReference type="EnsemblBacteria" id="ACA86739">
        <property type="protein sequence ID" value="ACA86739"/>
        <property type="gene ID" value="Swoo_2462"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2462"/>
    <dbReference type="eggNOG" id="COG5654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133611_0_1_6"/>
    <dbReference type="OMA" id="VTYCATS"/>
    <dbReference type="OrthoDB" id="1821714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014914">
        <property type="entry name" value="RES_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08808">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00953">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RES" evidence="2">
        <location>
            <begin position="16"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="156" mass="17547" checksum="6D852EF6B4C88A1F" modified="2008-04-29" version="1">MITGYRIVKKKWASNAFDGEGARLYGGRWNSRGQSCVYLAGSESLAILEVLVHLENAQQINQYALFSVTLSEEDILLLETQALPENWQEDPAPSETAELGDEWLCSQSSLALCVPSSIVARENNYLLNINHPHFHQLLSSMVELEFSMDSRLLSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG33</accession>
    <name>B1KG33_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endopeptidase La</fullName>
            <ecNumber evidence="1">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325082.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86740">
        <property type="protein sequence ID" value="ACA86740"/>
        <property type="gene ID" value="Swoo_2463"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2463"/>
    <dbReference type="eggNOG" id="COG1067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014785_0_1_6"/>
    <dbReference type="OMA" id="DWVYVNN"/>
    <dbReference type="OrthoDB" id="128102at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041699">
        <property type="entry name" value="AAA_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13654">
        <property type="entry name" value="AAA_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="2">
        <location>
            <begin position="570"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="660"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="816" mass="91048" checksum="B5F75978C6F8E147" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB5</accession>
    <name>B1KGB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326581.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3995"/>
    <dbReference type="EnsemblBacteria" id="ACA88252">
        <property type="protein sequence ID" value="ACA88252"/>
        <property type="gene ID" value="Swoo_3995"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3995"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_9_6"/>
    <dbReference type="OMA" id="EWDKTLA"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="22"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="450"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="537" mass="58688" checksum="CB9E86760B34155F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGJ6</accession>
    <name>B1KGJ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323671.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1031"/>
    <dbReference type="EnsemblBacteria" id="ACA85324">
        <property type="protein sequence ID" value="ACA85324"/>
        <property type="gene ID" value="Swoo_1031"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1031"/>
    <dbReference type="eggNOG" id="ENOG503230F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142731_1_0_6"/>
    <dbReference type="OMA" id="IQFVMID"/>
    <dbReference type="OrthoDB" id="1805329at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021559">
        <property type="entry name" value="DUF3019"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11456">
        <property type="entry name" value="DUF3019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764444" evidence="1">
        <location>
            <begin position="25"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15602" checksum="73E2FE5EB1E6FA6A" modified="2008-04-29" version="1" precursor="true">MQITKFITLLLLLLFIVGSSQIFADEADELGAKLMVAPEFCITSGDQLTCELKVLLEWQNQQPRAICILSDYEGMAKWCSEDDKVNSLSLNVSTTEDIQFVMIDKETHETLAGVKLKVTQTAEPKVRRRYRNPWSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK3</accession>
    <name>B1KGK3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1038"/>
    <dbReference type="EnsemblBacteria" id="ACA85331">
        <property type="protein sequence ID" value="ACA85331"/>
        <property type="gene ID" value="Swoo_1038"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1038"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_683085_0_0_6"/>
    <dbReference type="OMA" id="FDNYFVY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="263"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="380" mass="42522" checksum="802415EF70AC6BCB" modified="2008-04-29" version="1">MLYDNEDDILGAASIIAEQVDEYRTLLVDKTIGAQIKEYRPSVILLALSSVQKSIELYTEIITEQSLDYPHHSILLCKNRESSAAFRCCIKGLFDNYFVYQPLYEKFRLKMIVHNGLLISQATSQYIGFQDEQLESLEEDLETLIDEGGACKHSLLNSIADCKKSLATSSTEDPANSVSEQLLQKINETHIEPLLAELEGNIKAGLDNMINQLLVKQVGIKELENRVAEMNKTAIPDQQSILEALSTTASTLTNEKSAKDRIKILVVEDNQLYRDMLVNILKKENFDVDEAADGLNALQKIKRTQYALVLMDLFMPNLDGINTTKQIKAINGNKSLPVIALTGNKNKDLIKTWAEQGLKGYILKPSTKNEILEAVNKVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS6</accession>
    <name>B1KGS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325136.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2518"/>
    <dbReference type="EnsemblBacteria" id="ACA86795">
        <property type="protein sequence ID" value="ACA86795"/>
        <property type="gene ID" value="Swoo_2518"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2518"/>
    <dbReference type="eggNOG" id="ENOG5032RR9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096110_0_0_6"/>
    <dbReference type="OMA" id="LRQQCRW"/>
    <dbReference type="OrthoDB" id="1350108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017738">
        <property type="entry name" value="T6SS-assoc_VCA0118"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11319">
        <property type="entry name" value="VasI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03360">
        <property type="entry name" value="VI_minor_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767045" evidence="1">
        <location>
            <begin position="22"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="23563" checksum="38E12EFFD903552E" modified="2008-04-29" version="1" precursor="true">MSQGNGWILFGLLMTAASCYAAPQQLSDPKACVQIKSKLERLYCFDQAFMTPITVDDTQGSEQARVVEWVRAEASEANRQDETHFLLGQQEDNPNNVWLTATAIGALPPRPILMLSCIDEISRVELVVSEEIAQGSIYVAVNKPSSQGELWVSDNSGLVFRSGRGIPAIHLMKKMLLAQEFTLSSDNANFNDLQFDATGLKQAIKPLQKACRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU2</accession>
    <name>B1KGU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2534</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325152.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2534"/>
    <dbReference type="EnsemblBacteria" id="ACA86811">
        <property type="protein sequence ID" value="ACA86811"/>
        <property type="gene ID" value="Swoo_2534"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2534"/>
    <dbReference type="eggNOG" id="COG1230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_1_0_6"/>
    <dbReference type="OMA" id="WKRLIFS"/>
    <dbReference type="OrthoDB" id="948593at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="330" mass="37125" checksum="8DC1831F4279CDED" modified="2008-04-29" version="1">MTEKQHSIAPWQHPHQFAHLNHDGERNTRYVLYLTVITMIVEITAGTIYGSMALLADGWHMGTHAAAFMITLFAYYYARKHADNPDFSFGTGKVSVLGGFTSAIALGMVALIMLVESVVRFFSPHQIQFSEAIFVAIIGLTVNLISAVLLKDHHGHSHAHGHHHNEHEHEHEHEHEHEGHDHNLRAAYMHVLADALTSILAIVALLFGKWYGLTWLDPLMGVVGSIIITRWAWQLLGQTSPILLDRSIEDRYRLKITELIEAESDHQVADLHIWKVSADHYAAAISIVSHNPKDVEYFKAKLSDFTQVSHLTIELNTCRQAECLSSTAHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH97</accession>
    <name>B1KH97_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323751.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1112"/>
    <dbReference type="EnsemblBacteria" id="ACA85405">
        <property type="protein sequence ID" value="ACA85405"/>
        <property type="gene ID" value="Swoo_1112"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1112"/>
    <dbReference type="eggNOG" id="COG3450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147448_1_1_6"/>
    <dbReference type="OMA" id="KGTWEVL"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_3" evidence="1">
        <location>
            <begin position="41"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="13367" checksum="05D9E83792F33416" modified="2008-04-29" version="1">MNINSIVDISNNKTESEHYHLDDEKLISGNPAQAVENHFSSPCDQFHCGVWESEKGSWKVNYTESEYCEILAGSSVITDENGNTITVNEGSRFVIPAGFSGTWEVLDSCKKIYVMFEAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHB3</accession>
    <name>B1KHB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323767.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1128"/>
    <dbReference type="EnsemblBacteria" id="ACA85421">
        <property type="protein sequence ID" value="ACA85421"/>
        <property type="gene ID" value="Swoo_1128"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1128"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085376_1_4_6"/>
    <dbReference type="OMA" id="YDSVVPH"/>
    <dbReference type="OrthoDB" id="1292067at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="182" mass="20019" checksum="8B3582020C1D75F2" modified="2008-04-29" version="1">MDIGASLKAVRKIKGLSQRELAKRAGVTNSTISMIEKNSVSPSVSSLKKVLSGLPMSLVDFFSMEDTAASEAKVVYRSDELLDIGDGNLDYKLVGRDYPNRAMSVMSETYPPGSDTGEEMLKHEGEEAAIVIEGKFELTVGDEVFILETGDSYYFNSETPHRFRNPFDEDCRIVSATTPANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHD4</accession>
    <name>B1KHD4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1149</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323788.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1149"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85442">
        <property type="protein sequence ID" value="ACA85442"/>
        <property type="gene ID" value="Swoo_1149"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1149"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_9_1_6"/>
    <dbReference type="OMA" id="PMWVNAE"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041443">
        <property type="entry name" value="Exop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18559">
        <property type="entry name" value="Exop_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="81"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_3_C" evidence="4">
        <location>
            <begin position="447"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Exop_C" evidence="5">
        <location>
            <begin position="695"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="862" mass="93562" checksum="85291271FCE3E52B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE3</accession>
    <name>PLSY_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">G3P acyltransferase</fullName>
            <shortName evidence="1">GPAT</shortName>
            <ecNumber evidence="1">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="1">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">plsY</name>
        <name type="ordered locus">Swoo_1158</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PlsY family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323797.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHE3"/>
    <dbReference type="SMR" id="B1KHE3"/>
    <dbReference type="STRING" id="392500.Swoo_1158"/>
    <dbReference type="EnsemblBacteria" id="ACA85451">
        <property type="protein sequence ID" value="ACA85451"/>
        <property type="gene ID" value="Swoo_1158"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1158"/>
    <dbReference type="eggNOG" id="COG0344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081254_0_2_6"/>
    <dbReference type="OMA" id="WRHRGNL"/>
    <dbReference type="OrthoDB" id="1691856at2"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00023">
        <property type="entry name" value="TIGR00023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000136122" description="Glycerol-3-phosphate acyltransferase">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <sequence length="202" mass="21570" checksum="6E08CA07094EDEDF" modified="2008-04-29" version="1">MTITALTLGMILSAYLAGSISSAVLVCRLRGLPDPRTQGSGNPGATNVLRIGGVSSAALVLFFDMLKGALPAYIAFRLGLDSVSLGIIAIAACLGHIFPIFFHFKGGKGVATAFGAMAPIGPELALLLMGSWVLMVLICRYSSLAAIVTALLAPFYTWYLDDRFVLPVAMLSALIIIRHKENIQRLLKGEESKFSRKKTPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH2</accession>
    <name>B1KHH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gonadoliberin III-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325197.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2580"/>
    <dbReference type="EnsemblBacteria" id="ACA86857">
        <property type="protein sequence ID" value="ACA86857"/>
        <property type="gene ID" value="Swoo_2580"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2580"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041549_0_0_6"/>
    <dbReference type="OMA" id="AFRETQL"/>
    <dbReference type="OrthoDB" id="1099526at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025840">
        <property type="entry name" value="7TM_transglut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025838">
        <property type="entry name" value="Transglut_i_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14402">
        <property type="entry name" value="7TM_transglut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14400">
        <property type="entry name" value="Transglut_i_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Transglut_i_TM" evidence="2">
        <location>
            <begin position="24"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="7TM_transglut" evidence="3">
        <location>
            <begin position="257"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="504" mass="55750" checksum="7639049E80BBA55D" modified="2008-04-29" version="1" precursor="true">MHSKKPFYILVALLFISGIAASVFRGIEHNVPFLPGKQVQSWAVDAKVSFQGIGEPAEVSFSLPNDPAFEVLVENASSPGYGLTISQDNQDQERRALWSVRSATGLQNLYYKVTLIPTGTTQVIAEQEPTAPKDFIWPATEKDAAEQVISKVWAKSATNLTFAQQLNKALNAAERTQNVELLLSSNTPTKLFLHMLHSKGVPAQEVSGLYLEDQRRRQQLSSFVEVYNDGEWILFDPSNGTQGRKDNLLLWDRSGKSTLDVTGGVNSQVNFSMLQDTRSALATSLDVMKNQGALDFSLYQLPLEEQSLFKGILLIPIGVLMVVFLRVIVGLKTSGTFMPVLIALAFIQTTLLTGLIGFILIVACGLMIRSYLSQLNLLLISRISAVIIVVIGIIGIFTLLSYKFGLSEGLTITFFPMIILAWTIERMSILWEEEGPKEVLLQGGGSLFVATLAYLAMSATWVQHWVFNFLGIHLVILAIVLLMGQYTGYRLLELRRFKPLAGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHW9</accession>
    <name>B1KHW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326776.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4191"/>
    <dbReference type="ESTHER" id="shewm-b1khw9">
        <property type="family name" value="abh_upf00227"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88447">
        <property type="protein sequence ID" value="ACA88447"/>
        <property type="gene ID" value="Swoo_4191"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4191"/>
    <dbReference type="eggNOG" id="COG3150">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090996_2_0_6"/>
    <dbReference type="OMA" id="MLAHYPG"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008886">
        <property type="entry name" value="UPF0227/Esterase_YqiA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35602">
        <property type="entry name" value="PTHR35602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05728">
        <property type="entry name" value="UPF0227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="192" mass="21615" checksum="86EA845F9F54E17B" modified="2008-04-29" version="1">MLLYIHGFNSSPLSEKGIVTAQFMAEFYPDITFHQPQLPPDPTDGVTLLSSIVESALAQGETLNFIGSSLGGYYASYLVEKYGGRAVLINPAVKPFELFDEFIGSQYNPYTDEHYQVVAQHKDDVKAFNTEAILNPDRFLVLLQSGDEVLDYRQAVQKYHCCQLLLEAGGDHSFVGYDKKLKRICQFLFLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI79</accession>
    <name>B1KI79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323903.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1265"/>
    <dbReference type="EnsemblBacteria" id="ACA85557">
        <property type="protein sequence ID" value="ACA85557"/>
        <property type="gene ID" value="Swoo_1265"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1265"/>
    <dbReference type="eggNOG" id="COG3658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078451_0_0_6"/>
    <dbReference type="OMA" id="NPLGGYM"/>
    <dbReference type="OrthoDB" id="923657at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="7"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="24597" checksum="155780367A3E73A8" modified="2008-04-29" version="1">MNNKIKVWDLPTRIFHWGMIVLLGGLWWTADAGEMDWHQVLAYSLMVFIVFRLIWGVVGSDTSRFSHFIKPPKAVLDYMKLTKEQGVSSSIGHNPLGGYMVIALIMLVSAQLTTGLFATDEIFTEGPLYSLVSSETGSLMSWLHKKIFYVMLGFASIHVLAVVYHGLKGDKLITPMITGYKQVSEASGLELKFKPALMAFLLVALLAGLVGNYLIKPVVGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI89</accession>
    <name>B1KI89_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323913.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1275"/>
    <dbReference type="EnsemblBacteria" id="ACA85567">
        <property type="protein sequence ID" value="ACA85567"/>
        <property type="gene ID" value="Swoo_1275"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1275"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_51_6"/>
    <dbReference type="OMA" id="RTQKMQA"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="242"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="309"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="556"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="679" mass="75835" checksum="FAD0C0A8ED2E9B5E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIA0</accession>
    <name>B1KIA0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Na+ dependent nucleoside transporter domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2675</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325291.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86951">
        <property type="protein sequence ID" value="ACA86951"/>
        <property type="gene ID" value="Swoo_2675"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2675"/>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016813_4_2_6"/>
    <dbReference type="OMA" id="FITGQPK"/>
    <dbReference type="OrthoDB" id="437016at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="9">
        <location>
            <begin position="89"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="8">
        <location>
            <begin position="191"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="401" mass="41951" checksum="1297F341A017A637" modified="2008-04-29" version="1">MTALLGIVSILLFAWLLSVDRKSIPYRTVFLALGLQIFFALLVLYIPAGKSALEAVTGVVSGVIEYGNVGINFLFGDLASGKLGFVFAINVLGIIIFFSAMISALYHIGFMPMVINFIGGGLQRLLGTGRAESLSATANIFVGMVEAPLVIKPYLKGMSDSQFFAVMCCGLASVAGGTLVGYASLGVELSYLIAAAFMSAPAGLLMAKILMPPSKDSHQADEITSVELPRATNVIEALADGAMSGLRIAVAIGATLLAFVSVIALLNGMLGSVGAWFGYELSFELILGYMLSPMAWLLGIPRSEAITAGSLIGQKIVVNEFVAFINLMSIEDQLSAHSKAVITFALCGFANIGTMAVLIGGLGSIVPERREFIAKHGFRAIAAGVFANLMSAAIASVILSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB6</accession>
    <name>B1KIB6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Disulfide bond formation protein B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Disulfide oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">dsbB</name>
        <name evidence="17" type="ordered locus">Swoo_2691</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Cell inner membrane</location>
            <topology evidence="2 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the DsbB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325307.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2691"/>
    <dbReference type="EnsemblBacteria" id="ACA86967">
        <property type="protein sequence ID" value="ACA86967"/>
        <property type="gene ID" value="Swoo_2691"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2691"/>
    <dbReference type="eggNOG" id="COG1495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098660_2_0_6"/>
    <dbReference type="OMA" id="GGALYMQ"/>
    <dbReference type="OrthoDB" id="1859420at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00286">
        <property type="entry name" value="DsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003752">
        <property type="entry name" value="DiS_bond_form_DsbB/BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022920">
        <property type="entry name" value="Disulphide_bond_form_DsbB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023380">
        <property type="entry name" value="DsbB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02600">
        <property type="entry name" value="DsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158442">
        <property type="entry name" value="SSF158442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 15" id="KW-0143">Chaperone</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14 15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="15">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="15">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="15">
        <location>
            <begin position="90"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="15">
        <location>
            <begin position="164"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="15">
        <location>
            <begin position="40"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="15">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA86967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="18854" checksum="2F32D51004795EBA" modified="2008-04-29" version="1">MNPVTQFAQSRLAWLILAGTALGLELCALFFQYVMKLDPCVMCIYQRLAIFGILAAGLIGIIGHKNRFMRLIAILGWSVSAAWGLKLALELVDMQTNPSPFSTCSFLPEFPTWMPLHEWIPSLFMPTGMCNDIPWEMFGITMGQWMIGAFTAYLIALAVFAIPALSKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIH6</accession>
    <name>B1KIH6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heme NO binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2021" name="Protein Sci." volume="30" first="448" last="463">
            <title>Solution structures of the Shewanella woodyi H-NOX protein in the presence and absence of soluble guanylyl cyclase stimulator IWP-051.</title>
            <authorList>
                <person name="Chen C.Y."/>
                <person name="Lee W."/>
                <person name="Renhowe P.A."/>
                <person name="Jung J."/>
                <person name="Montfort W.R."/>
            </authorList>
            <dbReference type="PubMed" id="33236796"/>
            <dbReference type="DOI" id="10.1002/pro.4005"/>
        </citation>
        <scope>STRUCTURE BY NMR</scope>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325363.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="PDB" id="6OCV">
        <property type="method" value="NMR"/>
        <property type="chains" value="A=1-182"/>
    </dbReference>
    <dbReference type="PDB" id="6WQE">
        <property type="method" value="NMR"/>
        <property type="chains" value="A=1-182"/>
    </dbReference>
    <dbReference type="PDBsum" id="6OCV"/>
    <dbReference type="BMRB" id="B1KIH6"/>
    <dbReference type="SMR" id="B1KIH6"/>
    <dbReference type="STRING" id="392500.Swoo_2751"/>
    <dbReference type="EnsemblBacteria" id="ACA87027">
        <property type="protein sequence ID" value="ACA87027"/>
        <property type="gene ID" value="Swoo_2751"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2751"/>
    <dbReference type="eggNOG" id="COG1719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079260_1_1_6"/>
    <dbReference type="OMA" id="SARCMSH"/>
    <dbReference type="OrthoDB" id="1962710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038158">
        <property type="entry name" value="H-NOX_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011644">
        <property type="entry name" value="Heme_NO-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07700">
        <property type="entry name" value="HNOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="SSF111126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword evidence="4 5" id="KW-0002">3D-structure</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNOB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="4">
        <source>
            <dbReference type="PDB" id="6OCV"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="5">
        <source>
            <dbReference type="PDB" id="6WQE"/>
        </source>
    </evidence>
    <sequence length="182" mass="20825" checksum="350AB122E11C874D" modified="2008-04-29" version="1">MMGMVFTGLMELIEDEFGYETLDTLLESCELQSEGIYTSVGSYDHQELLQLVVKLSEVSSVPVTELVRLFGKKLFVELIEGHPEIANEMKDSFDLLSKIDSFIHVEVYKLYPQAELPKFTCDRLGDNDIRLHYQSKRPFASFAEGLLDGCAEYFKEDFTISRTPETQDSETDVIFNITRAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP2</accession>
    <name>B1KIP2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4282</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4282"/>
    <dbReference type="EnsemblBacteria" id="ACA88538">
        <property type="protein sequence ID" value="ACA88538"/>
        <property type="gene ID" value="Swoo_4282"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4282"/>
    <dbReference type="eggNOG" id="COG0652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_9_6"/>
    <dbReference type="OMA" id="NTANNEF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="15345" checksum="ACFD9A34AECE7245" modified="2008-04-29" version="1">MRYCEDGFYEGTIFHRVIKGFMVQGGGYTAQMHEKPTRAAIVNEANRGLKNTIGTLAMARTDAPHSATGEFFINLADNAFLDHTATTNQGWGYAVFGRVTSGMDVVNRMAKVKTCSKAGHDDVPQETLIIEKVTVIKQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ6</accession>
    <name>B1KIQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4297</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326879.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4297"/>
    <dbReference type="EnsemblBacteria" id="ACA88552">
        <property type="protein sequence ID" value="ACA88552"/>
        <property type="gene ID" value="Swoo_4297"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4297"/>
    <dbReference type="eggNOG" id="COG0670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1255244_0_0_6"/>
    <dbReference type="OMA" id="MMVSHID"/>
    <dbReference type="OrthoDB" id="1947455at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="PTHR23291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="24553" checksum="45FC13163FCE3C3C" modified="2008-04-29" version="1">MMESNVFERTSNGEQEISPSLYNFTIGAVLCWGFLVNWLMVGYISVESIQSINPWVFFIGYFASCFFGIYLFSKSSNPLVSFIGYNFVVVPFGLIINIVVSNYDPSLVLDAIMVTGLVTGIMMFLGTLFPAFFQKIVGVLTIALIAVIVVELFQIFVLGIHQGWIDWAVVIIFCGYIGYDWGRANQIPKTLDNAVDSAAALYMDIINLFLRILRIMGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ7</accession>
    <name>B1KIQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326880.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88553">
        <property type="protein sequence ID" value="ACA88553"/>
        <property type="gene ID" value="Swoo_4298"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4298"/>
    <dbReference type="HOGENOM" id="CLU_2002359_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="13977" checksum="27E472A1464D7FD7" modified="2008-04-29" version="1" precursor="true">MKILKTFSILALGIFTGFLSSVIYMQAQIAQASEEYREALLTLAEFSVEQSVTVGRAELSVLDELLNSIDRKVSNQGSAEEVMIDVAQYTLERIESIERLGIESQIEDVAKIKQRATDILEWYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIW3</accession>
    <name>B1KIW3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4 14">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_1319</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4 14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1319"/>
    <dbReference type="EnsemblBacteria" id="ACA85611">
        <property type="protein sequence ID" value="ACA85611"/>
        <property type="gene ID" value="Swoo_1319"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1319"/>
    <dbReference type="eggNOG" id="COG1194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_0_2_6"/>
    <dbReference type="OMA" id="RDPYRVW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01084">
        <property type="entry name" value="mutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="15">
        <location>
            <begin position="68"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA85611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="43297" checksum="8E9C655F154D6FAB" modified="2008-04-29" version="1">METRIDRLRLQKTLLIYMPLNMPVTEPIEANPDTFSSRIITWYDKFGRKHLPWQLEKTPYKVWVSEIMLQQTQVSTVIPYYLKFMERFPSIGALADAPQDEVLHYWTGLGYYARARNLHKSAQIIRDEFQGEFPTNFDNVLALPGIGRSTAGAVLSLSLGQHHAILDGNVKRVLARHDAIQGWPGQKAVENQLWSLTDSLTPKQDVQKYNQAMMDMGATICTRSKPSCDKCPVAIDCEAQLIGRQTEFPGKKPKKVTPEKSAWMLVIAKGEEVILEKRPPAGIWGGLWCFPQFSSREELDQYLQIKGIKVSQEELLLGFRHTFSHFHLDITPVVVNLDNQSDNQIMEDKPSVWYNLPNPPKVGLAAATERILAGLGSVLIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ09</accession>
    <name>B1KJ09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325365.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2753"/>
    <dbReference type="EnsemblBacteria" id="ACA87029">
        <property type="protein sequence ID" value="ACA87029"/>
        <property type="gene ID" value="Swoo_2753"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2753"/>
    <dbReference type="eggNOG" id="COG2733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077507_0_0_6"/>
    <dbReference type="OMA" id="EPFIEKM"/>
    <dbReference type="OrthoDB" id="373600at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="234" mass="25822" checksum="F11F3E025602F293" modified="2008-04-29" version="1" precursor="true">MNKSVITNLIAAILVVSGYLLAQPIIFSVGLFALSGAVTNWLAVHMLFEKIPGLYGSGVIPTRFEEFKTGIANLMMKQFFTDENIDRFLSAEGVESHINLQPVIEKIDLAPAFDALVTTVEQSSLGGMLAMFGGSEAITPLREPFIEKMKLSLVDISQSEDFINLVKSELERPDVLDDMRTKVNEIVTQRLDELTPELVKDIIQEMIREHLGWLVVWGGVFGGVIGLIAAMLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ50</accession>
    <name>B1KJ50_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325406.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2795"/>
    <dbReference type="EnsemblBacteria" id="ACA87070">
        <property type="protein sequence ID" value="ACA87070"/>
        <property type="gene ID" value="Swoo_2795"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2795"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_16_6"/>
    <dbReference type="OMA" id="GMTPYAW"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="176"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="275" mass="31624" checksum="5658F63C6D48EB70" modified="2008-04-29" version="1">MMTPEHIEYWHNPVLPEIELSRAKLTQFEFQKHIHLDYHVGVVSHGCQQYCHKGNTYLLTPGSISTLNPDETHNGQSRNAEGYEAHVLSIPAHYVKQVSDELNQGELFFNSPLIDTPRLQFAFLQLHQMLTSTQQFSSLEIETSMMAFTTELFSKHSELQPVKQNITTGLSHQQICQIRELFHDDLSHTFQLETLAVKFNLSKFQFLRAFKKTVGMTPHAYLKRVRLEHAKKAIINGGALSDIANQVGFFDQSHLNKAFKHAYLITPAHFQRRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ78</accession>
    <name>B1KJ78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proline racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline racemase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325434.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2823"/>
    <dbReference type="EnsemblBacteria" id="ACA87098">
        <property type="protein sequence ID" value="ACA87098"/>
        <property type="gene ID" value="Swoo_2823"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2823"/>
    <dbReference type="eggNOG" id="COG3938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036729_0_0_6"/>
    <dbReference type="OMA" id="SHVLWTG"/>
    <dbReference type="OrthoDB" id="559014at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="PTHR33442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="333" mass="36248" checksum="C20CDBC5ADC075E3" modified="2008-04-29" version="1">MLKGTFFCVDAHTCGNPVRLVTSGHPDLKGCTMSEKRQDFLNHYDWIRKALMFEPRGHDMMSGAFLYPPCSDNADASILFIETSGCLPMCGHGTIGTVTAAIESGLLTAKKPGKLVIDVPAGQINIDFQQTGDKVDWVKIYNVPAYLAHSDVILDIPELGPLKVDVSYGGNYYVIVEPQTNYPGLRHWSAADILRWSPMIRQIAHEQLSCIHPDDPTVSGVSHVLWTGDTISEGSDGANAVFYGDKAIDRSPCGTGTSARLAQLYTKGQLKVGDQYTHESIIGSQFIGRIESATQVGTHPAIMPSIQGWARITGKNTITVDDSDPYAFGFQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ88</accession>
    <name>B1KJ88_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2833</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325444.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2833"/>
    <dbReference type="EnsemblBacteria" id="ACA87108">
        <property type="protein sequence ID" value="ACA87108"/>
        <property type="gene ID" value="Swoo_2833"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2833"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_15_6"/>
    <dbReference type="OMA" id="SKMNAGM"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="222"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="459"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="576" mass="64872" checksum="ED69B7921FFCE740" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG9</accession>
    <name>B1KJG9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326967.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4389"/>
    <dbReference type="EnsemblBacteria" id="ACA88641">
        <property type="protein sequence ID" value="ACA88641"/>
        <property type="gene ID" value="Swoo_4389"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4389"/>
    <dbReference type="eggNOG" id="COG3028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106757_2_0_6"/>
    <dbReference type="OMA" id="QMQFVGK"/>
    <dbReference type="OrthoDB" id="1711519at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd16331">
        <property type="entry name" value="YjgA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023153">
        <property type="entry name" value="PSPTO4464-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006839">
        <property type="entry name" value="Ribosome-assoc_YjgA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38101">
        <property type="entry name" value="PTHR38101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04751">
        <property type="entry name" value="DUF615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016183">
        <property type="entry name" value="UCP016183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158710">
        <property type="entry name" value="SSF158710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="20690" checksum="C91647C5BC2DDF37" modified="2008-04-29" version="1">MNIVGDSEHFKQPFDHDEDYVSRADAKREIAIYQELGMKLVALSKTQLSKLELDELIYDNVLKTKTIKVNTEAYRRHLQYIGKLMRNVDVEALQQDIKNVLNQNSNESAKQNVAEKLKDQLITEGDDAVQALVEKHPGLERQKLRQLIRQTKKELTKKPEQTSKSAVELVKYLRTEIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJH0</accession>
    <name>B1KJH0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ig domain protein group 1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intimin/invasin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326968.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4390"/>
    <dbReference type="EnsemblBacteria" id="ACA88642">
        <property type="protein sequence ID" value="ACA88642"/>
        <property type="gene ID" value="Swoo_4390"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4390"/>
    <dbReference type="eggNOG" id="COG2831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006970_0_0_6"/>
    <dbReference type="OMA" id="CGTGQAN"/>
    <dbReference type="OrthoDB" id="416508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003344">
        <property type="entry name" value="Big_1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51127">
        <property type="entry name" value="BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Big-1" evidence="2">
        <location>
            <begin position="163"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="843" mass="87282" checksum="AAB4F55CBC1368FB" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK00</accession>
    <name>B1KK00_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trpD</name>
        <name evidence="8" type="ordered locus">Swoo_2914</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325523.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2914"/>
    <dbReference type="EnsemblBacteria" id="ACA87187">
        <property type="protein sequence ID" value="ACA87187"/>
        <property type="gene ID" value="Swoo_2914"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2914"/>
    <dbReference type="eggNOG" id="COG0547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034315_2_1_6"/>
    <dbReference type="OMA" id="GPMTNPA"/>
    <dbReference type="OrthoDB" id="1238435at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 5 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="7">
        <location>
            <begin position="12"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="6">
        <location>
            <begin position="87"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="96"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="103"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="121"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="351" mass="36725" checksum="0090B955D5783DA6" modified="2008-04-29" version="1">MSQTEQPTELQPILDKLYSGQSATRLEAKQLFSSIIAGEMSETAMAGMLVAMKMRGESIDEISGAADALRTAAKAFPAPCEATRTKGVVDIVGTGGDGHNTINISTTAAFVAAASGANVAKHGNRSVSSKSGSSDLLAQFGIDLTMAPETARDCLDELGLCFLFAPHYHGGVRHAVPVRQALKTRTLFNVLGPLINPSHPDFILLGVYSPELVKPIAEVLKALGMKRAMVVHGSGLDEVAIHGDTLVCELNNAEITQYTLTPEQLGLPQSKLTDLEGGTPEENAQYTRAILQGKGQAAHQHAVAANAGCALYISGVSDSVESGTQLALETIASGRAYQLLQQLASASSATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK79</accession>
    <name>B1KK79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methionine synthase vitamin-B12 independent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327036.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4458"/>
    <dbReference type="EnsemblBacteria" id="ACA88710">
        <property type="protein sequence ID" value="ACA88710"/>
        <property type="gene ID" value="Swoo_4458"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4458"/>
    <dbReference type="eggNOG" id="COG0620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040013_3_0_6"/>
    <dbReference type="OMA" id="DPDCGMR"/>
    <dbReference type="OrthoDB" id="577156at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016456">
        <property type="entry name" value="Met_Synthase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005632">
        <property type="entry name" value="Met_synth_catalytic_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Meth_synt_2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="342" mass="38568" checksum="487966DE8CC67CF7" modified="2008-04-29" version="1">MKTLLPTSTAGSLPKPSWLAQPETLWSPWKLEGEALIDGKHDALRVSLQEQQQSGVDIVSDGEQTRQHFVTTFIEHLSGVDFENRKTVRIRDRYDASVPTIVGPISRQKPVFVEDAKFLRQQTKQPIKWALPGPMTMIDTLYDDHYQSREQLAWEFAKILNQEAKELEAAGVDIIQFDEPAFNVFFDEVNDWGIACLERAIEGLKCETAVHICYGYGIKANTDWKKTLGTEWRQYEEVFPKLQQSSIDIISLECHNSHVPIELLELIRGKKVMVGAIDVASDTIETPEEVANTLRKALEFVDADKLYPCTNCGMAPLSRRVARDKLNALSAGAAIVRKELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK90</accession>
    <name>B1KK90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic copper-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4470"/>
    <dbReference type="EnsemblBacteria" id="ACA88721">
        <property type="protein sequence ID" value="ACA88721"/>
        <property type="gene ID" value="Swoo_4470"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4470"/>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041882_0_1_6"/>
    <dbReference type="OMA" id="RYGLHFM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006633">
        <property type="entry name" value="Carb-bd_sugar_hydrolysis-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026464">
        <property type="entry name" value="NosD_copper_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007742">
        <property type="entry name" value="NosD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022441">
        <property type="entry name" value="Para_beta_helix_rpt-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05048">
        <property type="entry name" value="NosD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00722">
        <property type="entry name" value="CASH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04247">
        <property type="entry name" value="NosD_copper_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03804">
        <property type="entry name" value="para_beta_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASH" evidence="1">
        <location>
            <begin position="58"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="CASH" evidence="1">
        <location>
            <begin position="212"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="49197" checksum="A015C03D6B682AAB" modified="2008-04-29" version="1" precursor="true">MKKSMNNFALKQVANGLKTATKGLCLSAWLTLFINPLTMAATYSVSDTESLKLQLETVKAGDTVLLLDGEYLGHFEIHQPITLTGEGSAIIDAQGRGRAIAVFSSGVSLKNLTIQNWGGDLYELDAGVFIHEQAERVHIESSRLQGDGFGIYAENSKHIIVNNNIIAGNNALYKLDRGDGVYLKGVDVSVIHDNQISDVRDGVYLETSTNSQVFDNRFHSAQYGIHYMYTKHDEAYGNEVDSVDGGYAIMSSEFVNLHHNQVSNAIDFGVLLNISKHSIVNNNQVSLAHNPQGAAELGNEGKGIFIYGARDNEVTHNLFSTSDIGIYMAMGGEGNKVYGNQFVNNQIQVKYVGDALLEWSHQGKGNFWSGYMGWDSNHDGIADKPYRPNDSLDKLFWLYPEARFLMNSPVVALLRWVQSQFDIGEPTGIVDSFPLLNNVSSDRVQN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR3</accession>
    <name>MNMC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC</fullName>
            <shortName evidence="1">tRNA mnm(5)s(2)U biosynthesis bifunctional protein</shortName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">tRNA (mnm(5)s(2)U34)-methyltransferase</fullName>
                <ecNumber evidence="1">2.1.1.61</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">FAD-dependent cmnm(5)s(2)U34 oxidoreductase</fullName>
                <ecNumber evidence="1">1.5.-.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">mnmC</name>
        <name type="ordered locus">Swoo_3009</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-aminomethyl-2-thiouridine(34) in tRNA + S-adenosyl-L-methionine = 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19569"/>
            <dbReference type="Rhea" id="RHEA-COMP:10195"/>
            <dbReference type="Rhea" id="RHEA-COMP:10197"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74454"/>
            <dbReference type="ChEBI" id="CHEBI:74455"/>
            <dbReference type="EC" id="2.1.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the DAO family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.61" evidence="1"/>
    <dbReference type="EC" id="1.5.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325616.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKR3"/>
    <dbReference type="SMR" id="B1KKR3"/>
    <dbReference type="STRING" id="392500.Swoo_3009"/>
    <dbReference type="EnsemblBacteria" id="ACA87280">
        <property type="protein sequence ID" value="ACA87280"/>
        <property type="gene ID" value="Swoo_3009"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3009"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022427_2_1_6"/>
    <dbReference type="OMA" id="MGCAPDF"/>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016645">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004808">
        <property type="term" value="F:tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002097">
        <property type="term" value="P:tRNA wobble base modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01102">
        <property type="entry name" value="MnmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023032">
        <property type="entry name" value="tRNA_MAMT_biosynth_bifunc_MnmC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017610">
        <property type="entry name" value="tRNA_S-uridine_synth_MnmC_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03197">
        <property type="entry name" value="MnmC_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000348038" description="tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC">
        <location>
            <begin position="1"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="tRNA (mnm(5)s(2)U34)-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="FAD-dependent cmnm(5)s(2)U34 oxidoreductase">
        <location>
            <begin position="287"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01102"/>
        </source>
    </evidence>
    <sequence length="696" mass="77215" checksum="62C05429BD8D0F01" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKT6</accession>
    <name>B1KKT6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327068.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4491"/>
    <dbReference type="EnsemblBacteria" id="ACA88742">
        <property type="protein sequence ID" value="ACA88742"/>
        <property type="gene ID" value="Swoo_4491"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4491"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_764823_0_0_6"/>
    <dbReference type="OMA" id="GCNMTYG"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764622" description="Peptidase S1 domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="150"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="39011" checksum="28587D49DCCA60C0" modified="2008-04-29" version="1" precursor="true">MEINHKVIVCSCMGIYMSLLFGSGIANADTSLIKISEVKEKSAPKNVAALIDKQLKMDQATPMEWPEYVVSKGEQEEIISGGSGSADSQLAPFGANDDAKALYPEAWKAMEEMVITEEYSSSDYDAKSAAKPDLYTGYPANKYSQSWKYHPWRTMGKLYFNKPSGGSSYCSASMLKNNVLLTAAHCVYSRGSGWHSNLVFAPAERYGNKPYGQYNWTSAIVLTNWINVGSRQYDLALVRLSGNPNGMVGNLGYAYGQSFEQSLFSFGYPGNLGSGQYSNTCAAESFKDDTDAIGMGCNMTYGASGGPWLRKFTPYVSGGNQANSVVSGPSKKGTFGQSFVGPRFTSNNFRVLCNSYGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ3</accession>
    <name>B1KKZ3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="13">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">leuB</name>
        <name evidence="16" type="ordered locus">Swoo_4549</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327125.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4549"/>
    <dbReference type="EnsemblBacteria" id="ACA88799">
        <property type="protein sequence ID" value="ACA88799"/>
        <property type="gene ID" value="Swoo_4549"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4549"/>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_3_6"/>
    <dbReference type="OMA" id="EYDLGAR"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01033">
        <property type="entry name" value="LeuB_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="PTHR42979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0520">NAD</keyword>
    <keyword evidence="10 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="15">
        <location>
            <begin position="4"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA88799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="364" mass="39297" checksum="40DA1F02099353D7" modified="2008-04-29" version="1">MSYQIAVLAGDGIGPEVMAEARKVLSAVEERFELAIEYSEYDIGGAAIDNHGCPLPDVTLKGCEAADAILFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHSGLEHMSPLRSDISSKGFDVLCVRELTGGIYFGKPKGRQGEGESEEAFDTMRYSRKEIRRIAKIAFEAAQGRRKKVTSVDKANVLACSVLWREVVEEVAKDFPDVELEHIYIDNATMQLLRRPNEFDVMLCSNLFGDIISDEIAMLTGSMGLLSSVSLNSKGFGLYEPAGGSAPDIAGQGIANPVAQILSAALLLRHSLKLEEAATAIEAAVGKALSDGYLTGELLPADERVNAKTTSQMGDYIAQVIKEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL13</accession>
    <name>B1KL13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YicC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327144.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4569"/>
    <dbReference type="EnsemblBacteria" id="ACA88819">
        <property type="protein sequence ID" value="ACA88819"/>
        <property type="gene ID" value="Swoo_4569"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4569"/>
    <dbReference type="eggNOG" id="COG1561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076609_0_0_6"/>
    <dbReference type="OMA" id="EIKSVNH"/>
    <dbReference type="OrthoDB" id="1509828at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005229">
        <property type="entry name" value="CHP00255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013551">
        <property type="entry name" value="DUF1732"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013527">
        <property type="entry name" value="YicC-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30636">
        <property type="entry name" value="PTHR30636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08340">
        <property type="entry name" value="DUF1732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03755">
        <property type="entry name" value="YicC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00255">
        <property type="entry name" value="TIGR00255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YicC_N" evidence="1">
        <location>
            <begin position="2"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1732" evidence="2">
        <location>
            <begin position="203"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="287" mass="32987" checksum="FD17F92D7944A46E" modified="2008-04-29" version="1">MIQSMTAYARIEHKAEWGTASWEIRSVNQRYLETYLRLPEHFRSLEPLLRDRLRKRLNRGKIEVNLRYDLADNKNSELQLNQDLAKQLVNAANWVKQEAGQGELNLVDILKWPGVMSGSEQDMDALGKELLTAFDSAIDQFIEARGREGEAIKTMLQTRLDAIVEQVAIVREHMPTVMQWQRDKLTNRLAEITGELDPARLEQEMVILAQKMDVAEEMDRLDAHVAETQRILKKGGAQGRRLDFMMQEFNRESNTLASKSISAEVTAAAVELKVLIEQMREQIQNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL39</accession>
    <name>B1KL39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322729.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84380">
        <property type="protein sequence ID" value="ACA84380"/>
        <property type="gene ID" value="Swoo_0079"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0079"/>
    <dbReference type="eggNOG" id="ENOG5033ENG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1617889_0_0_6"/>
    <dbReference type="OMA" id="WYLIPPS"/>
    <dbReference type="OrthoDB" id="2025200at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="17950" checksum="60FD829620FEC3CD" modified="2008-04-29" version="1" precursor="true">MALSRKKWNNILIFATASMIAILTLLDDRTAELPSDAAPLFDDKAPLAQLQLDELWLSKGSQWQCHEDVLNCKTWATAWSEIQLSPVADQQGLMEQESLDAPINVTILVANNSQGQAWLWYPAHGLLVSPAKNWYQIPPSLREALTPITKISAAPLNDTTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL41</accession>
    <name>B1KL41_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">T5orf172 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322731.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0081"/>
    <dbReference type="EnsemblBacteria" id="ACA84382">
        <property type="protein sequence ID" value="ACA84382"/>
        <property type="gene ID" value="Swoo_0081"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0081"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024787_2_1_6"/>
    <dbReference type="OrthoDB" id="405099at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="SMART" id="SM00974">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="T5orf172" evidence="3">
        <location>
            <begin position="355"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="463" mass="52618" checksum="BFFE3F88F2105B0A" modified="2008-04-29" version="1">MVAIDMNILIAGVVLCFIGISALFFTLKKRKSILLTATKEAETLLSQSQAKASNIVNSAEKTKKNLLDEAENRKRFLLEEAEQGVIPFHERVERLKLADKEITSRLKQSRSIIDDITDKSCSHAADIELLTEEDLLSSQSYQDDRKDVKARLKKLAVNAIDGVRGSGSNVNIGKFVSISAKADMAGALLLTTVEMLCTKTNANNGHQALEKLSESIIATEALIKCIDSRATINQEFKALLIKRLEIEIHFKKAKQLAKEEQRELREQEKEERNARQEAERIQKEAEKEERIKSDAIAELEKKMAEKSDAEKAIYQEELNRLKLELEEAHQKFERAKSRAQETKQGHVYVISNIGSFGEDILKIGMTRRMDPMDRVKELSDASVPFTFDVHALIESDDAPNLESTLHKVFDDKRVNKVNRRKEYFNVNLSEIEQELQRLDINALINKVASADEYYQSIRLEKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC8</accession>
    <name>B1KLC8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyd operon protein YbgT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1567</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324199.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1567"/>
    <dbReference type="EnsemblBacteria" id="ACA85853">
        <property type="protein sequence ID" value="ACA85853"/>
        <property type="gene ID" value="Swoo_1567"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1567"/>
    <dbReference type="eggNOG" id="COG4890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_207013_4_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011724">
        <property type="entry name" value="Cyd_oper_YbgT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012994">
        <property type="entry name" value="YbgT_YccB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08173">
        <property type="entry name" value="YbgT_YccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02106">
        <property type="entry name" value="cyd_oper_ybgT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="38" mass="4494" checksum="CAF7F3F4F4D244AC" modified="2008-04-29" version="1" precursor="true">MWYFAWILGVLLACSFGIINALWLENTENMDRDTENKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH7</accession>
    <name>B1KLH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Two component, sigma54 specific, transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324248.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1616"/>
    <dbReference type="EnsemblBacteria" id="ACA85902">
        <property type="protein sequence ID" value="ACA85902"/>
        <property type="gene ID" value="Swoo_1616"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1616"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_0_6"/>
    <dbReference type="OMA" id="ARYIHQQ"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029995">
        <property type="entry name" value="TR_FlbD/FleR/FlgR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32071:SF21">
        <property type="entry name" value="PTHR32071:SF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="138"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="452" mass="49862" checksum="FFA5C72CDE63083E" modified="2008-04-29" version="1">MSEGKLLLVEDDHSLREALLDTLLIAHYDCVDVASAEDAIVKLKHESFDMVISDVQMEGVGGLGLLNYLQQHHPQLPMLLMTAYATIDNAVNAIKLGAVDYLAKPFAPEVLLNQVSRYLKPKLCQTQPVVADEKSLALLSLAQKVAASDASVMIMGPSGSGKEVLARFIHQNSPRAEQPFVAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEISEMELGLQAKLLRVLQEREVERIGGRKNIKLDVRVLATSNRDLKSMAASGDFREDLYYRINVFPLVWPSLNQRPADILPLARHLLLRHATTSGMSEIPDFEESASRRLLTHRWPGNVRELDNVIQRALILFTGGNITANEIIIDADEVMLTQDVKCHTSTQESSLELDALGDELKAQEHVIILETLTQCQGSRKLVAEKLGISARTLRYKMAKMRDAGIQIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLN4</accession>
    <name>B1KLN4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SMC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325667.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3060"/>
    <dbReference type="EnsemblBacteria" id="ACA87331">
        <property type="protein sequence ID" value="ACA87331"/>
        <property type="gene ID" value="Swoo_3060"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3060"/>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004785_2_1_6"/>
    <dbReference type="OMA" id="ISHVQEM"/>
    <dbReference type="OrthoDB" id="1143316at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="5"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="374"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="544"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="663"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1018" mass="112794" checksum="674640B83AFEF277" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLX8</accession>
    <name>B1KLX8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327183.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4608"/>
    <dbReference type="EnsemblBacteria" id="ACA88858">
        <property type="protein sequence ID" value="ACA88858"/>
        <property type="gene ID" value="Swoo_4608"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4608"/>
    <dbReference type="eggNOG" id="ENOG5033MYU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1309414_0_0_6"/>
    <dbReference type="OMA" id="TIPCRQI"/>
    <dbReference type="OrthoDB" id="2073232at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021675">
        <property type="entry name" value="DUF3261"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11659">
        <property type="entry name" value="DUF3261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="199" mass="22412" checksum="8DD89EE54D758CFF" modified="2008-04-29" version="1" precursor="true">MMSKTRQRRIRWSYLISLILILFTTACSHTLQRQTCVALANEVNYCLAPIPANSQIHSLTQQVSIGVDEEHHELLTQLELDKQQLTLVGLAPLGQALFTLVFDGNTLSSQQSMLLGDEFKAEYLLALIQLAYWPTEDVNSYLQGASLVSQACDAARCRTIYASQNEEIIEISYDQIDPWRAVIELAIPQAKFKLKITPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM21</accession>
    <name>B1KM21_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">DNA-binding transcriptional regulator NtrC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nitrogen regulation protein NR(I)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ntrC</name>
        <name evidence="12" type="ordered locus">Swoo_4651</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4651"/>
    <dbReference type="EnsemblBacteria" id="ACA88901">
        <property type="protein sequence ID" value="ACA88901"/>
        <property type="gene ID" value="Swoo_4651"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4651"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_6_6"/>
    <dbReference type="OMA" id="DWTGNIR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010114">
        <property type="entry name" value="Transcript_reg_NtrC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01818">
        <property type="entry name" value="ntrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="10">
        <location>
            <begin position="139"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="469" mass="52184" checksum="22DF4E7DA0078DF4" modified="2008-04-29" version="1">MNEQVWVLDDDSSIRWVVERALKGAEISSTSFAAAESLWDALDHGQPKVIISDIRMPGTDGLTLLERIQVHYPHIPVIIMTAHSDLDSAVNAYQAGAFEYLPKPFDIDEAIALVERALTHSNEQIVKQNDELTVKAPEIIGEAPAMQEVFRAIGRLSRSSISVLINGQSGTGKELVAGALHKHSPRKEKPFIAINMAAIPKDLIESELFGHEKGAFTGAAAVRQGRFEQANGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGHSPVQVDVRIIAATHQDLELLVQKGEFREDLYHRLNVIRVHLPALSQRREDIPQLARHFLSSAAKEIAVEPKSLTKETAEKLSQLPWPGNVRQLENTCRWLMVMASGQEILPQDLPPELLQEPSQTNSLSTGEPADWQESLKLWIDERLTAGENDLLTEVQPAFERILLQTALAHTNGHKQEAAKRLGWGRNTLTRKLKELSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM29</accession>
    <name>B1KM29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heme exporter protein CcmA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4659</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327233.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4659"/>
    <dbReference type="EnsemblBacteria" id="ACA88909">
        <property type="protein sequence ID" value="ACA88909"/>
        <property type="gene ID" value="Swoo_4659"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4659"/>
    <dbReference type="eggNOG" id="COG4133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="NLAWLCA"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015439">
        <property type="term" value="F:ABC-type heme transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005895">
        <property type="entry name" value="ABC_transptr_haem_export_CcmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43499">
        <property type="entry name" value="PTHR43499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01189">
        <property type="entry name" value="ccmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="11"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="216" mass="24139" checksum="51B6B7514835229C" modified="2008-04-29" version="1">MVEQNSSKALLSANQLTCIREERILFDELSFEITAGEIVQIEGPNGSGKTSLLRILAGLSRPYAGDVHYQGENITRVRDEFNDDLLYLGHLAGVKSELTAEENLNFNLRISGYDEFETGDILAKVNLAGFEEALAGHLSAGQHRRTALARLWHTNCKIWLLDEPFTAIDKKGVEELEHLFLAHSKRGGCVVLTTHQDMGIIGDDILRKISLEYRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB2</accession>
    <name>B1KMB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenylacetate degradation, enoyl-CoA hydratase paaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322874.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0224"/>
    <dbReference type="EnsemblBacteria" id="ACA84525">
        <property type="protein sequence ID" value="ACA84525"/>
        <property type="gene ID" value="Swoo_0224"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0224"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_2_6"/>
    <dbReference type="OMA" id="LDCEKPV"/>
    <dbReference type="OrthoDB" id="1275789at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011968">
        <property type="entry name" value="PaaB1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02280">
        <property type="entry name" value="PaaB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="28528" checksum="9E885D7E33FC00AD" modified="2008-04-29" version="1">MDKAILLEKINGYACIKLNRPECLNSFNQQMHKELADILDVLHHDDSIRALILTGEGKGFCAGQDLSDRSVNQDDSPTDLGESVEHFYNPLIRRITAMPKPVICAVNGVAAGAGASIAMACDIVIAAKKSSFILSFSKVGLVPDSGASWHLPRAIGLPRAKALALLGNRLDADIAERWGLIWQVVNGDVLMETAHAMATELASRPTQAFANIKRLLNESFNSPMAQQMESERVAMQVLGFAHDYQEGVDAFLTKRTPIFIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMF5</accession>
    <name>B1KMF5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-ketoacyl-acyl-carrier-protein synthase I</fullName>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324299.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1667"/>
    <dbReference type="EnsemblBacteria" id="ACA85953">
        <property type="protein sequence ID" value="ACA85953"/>
        <property type="gene ID" value="Swoo_1667"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1667"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_1_0_6"/>
    <dbReference type="OMA" id="SCVLQHR"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="3">
        <location>
            <begin position="112"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="2">
        <location>
            <begin position="236"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="36196" checksum="A1DD6D503008F424" modified="2008-04-29" version="1">MISISNVSIKGIATTIPSSKVTNSDLGALYGEKEITKLISSVGVNTRRVADTNTTSADLCYDSAVNLINELEWEPESIGAIIFVSQTGEYQLPATACILQNRLGLPVSSIAYDVNLGCSGYTYGLFLASSLVQTGIKRVLLLVGDTISKLVKPGDRSTELLFGDAGTATGLEFETGPVIHFELGSDGSGAEHIIARNPQPQVNSIRGLNCAFLEMNGGEVFTFTLKRVPLLVNGFLEALELTSKDIDSCVYHQANHFMIKHLSKKSKFEPSQVPVSITEFGNTSCASIPLTLCTQNLISRNRMLLVGFGVGLSWGAVMVDLSTTKLLPVSEIKINEQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMK3</accession>
    <name>PHS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative pterin-4-alpha-carbinolamine dehydratase</fullName>
            <shortName evidence="1">PHS</shortName>
            <ecNumber evidence="1">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Pterin carbinolamine dehydratase</fullName>
            <shortName evidence="1">PCD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1716</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324347.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMK3"/>
    <dbReference type="SMR" id="B1KMK3"/>
    <dbReference type="STRING" id="392500.Swoo_1716"/>
    <dbReference type="EnsemblBacteria" id="ACA86001">
        <property type="protein sequence ID" value="ACA86001"/>
        <property type="gene ID" value="Swoo_1716"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1716"/>
    <dbReference type="eggNOG" id="COG2154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081974_2_2_6"/>
    <dbReference type="OMA" id="FHHPGIL"/>
    <dbReference type="OrthoDB" id="1862336at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00434">
        <property type="entry name" value="Pterin_4_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000192937" description="Putative pterin-4-alpha-carbinolamine dehydratase">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00434"/>
        </source>
    </evidence>
    <sequence length="112" mass="12879" checksum="546197E4852AABF0" modified="2008-04-29" version="1">MTKLADMKCEACQADAPKVTDSELAELIRLIPDWGVEVRDGIMQLERVYKFKNFKLAMEFTNKLAELAEEEFHHPGILTEWGKVTVTWWSHSVKGLHRNDFIMASKTDQLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP1</accession>
    <name>B1KMP1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325755.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3148"/>
    <dbReference type="EnsemblBacteria" id="ACA87419">
        <property type="protein sequence ID" value="ACA87419"/>
        <property type="gene ID" value="Swoo_3148"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3148"/>
    <dbReference type="eggNOG" id="ENOG502Z86E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087574_0_0_6"/>
    <dbReference type="OMA" id="AFGAEYH"/>
    <dbReference type="OrthoDB" id="1016175at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021323">
        <property type="entry name" value="DUF2927"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11150">
        <property type="entry name" value="DUF2927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765065" evidence="1">
        <location>
            <begin position="23"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="258" mass="29074" checksum="A3A667E1974B4FBA" modified="2008-04-29" version="1" precursor="true">MKNKLNHLLVLLCLFVSVSSLASDWKTPEYLQQAFVEVALRNEYDTGKHLVRKWTQPIGIWLDHRVGDEKKHEALARMHMEHLSAITGHELQLVNKLDQANVHLVFTRQSRWLQEVKSLLGPGAAKNLHGAVCMANVATNTKDEIVKAWIVIPVDQAQMHGKLLACVVEELTQIMGLPNDSDKVYPSIFNDKTPQDLLSGLDGILLKMLYHKEVIPGMDETRVKAIFTPVLKSWARDGTLANADKVIREGKLYPLLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP3</accession>
    <name>B1KMP3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325757.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3150"/>
    <dbReference type="EnsemblBacteria" id="ACA87421">
        <property type="protein sequence ID" value="ACA87421"/>
        <property type="gene ID" value="Swoo_3150"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3150"/>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_227494_0_0_6"/>
    <dbReference type="OrthoDB" id="956253at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044016">
        <property type="entry name" value="Big_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19077">
        <property type="entry name" value="Big_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2645"/>
            <end position="2663"/>
        </location>
    </feature>
    <feature type="domain" description="Big_13" evidence="2">
        <location>
            <begin position="901"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="2670" mass="281353" checksum="A0DC41E8DCA85117" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMU4</accession>
    <name>B1KMU4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3202</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3202"/>
    <dbReference type="EnsemblBacteria" id="ACA87472">
        <property type="protein sequence ID" value="ACA87472"/>
        <property type="gene ID" value="Swoo_3202"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3202"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_0_1_6"/>
    <dbReference type="OMA" id="TNVCCTT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="4">
        <location>
            <begin position="14"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="5">
        <location>
            <begin position="279"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="400" mass="41500" checksum="1ACB66492A4B588D" modified="2008-04-29" version="1">MEWKMSTEQLSQEIVIVAAKRTPMGGFQGALSTVPSPKLAATAIKGLITQTGVSVDAVDEVLMGCVLPAGLGQAPARQATLGAGLPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSAGIVVAGGMESMSQAPYLLDKARGGMRMGHGKVMDHMFLDGLEDAYTGGAMGTFAQKTADDFKLTREQMDAFSLSSLEKANKAIETGAFNDEITPVTVESRRGDTIVEIDEQPGNARPDKIPTLRPAFTKDGTITAANSSSISDGAAALMLMTAQQANVLGLPVLATIKGHTTHAQEPSMFTTAPVGAMNKLFEKVNWSVDDVDLFEINEAFAMVTMLAISELSIDADKVNVNGGACALGHPIGCSGARVLVTLIHALHARGLKRGVASLCIGGGESTAMAIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV4</accession>
    <name>B1KMV4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1,4-dihydroxy-2-naphthoate octaprenyltransferase</fullName>
            <shortName evidence="7">DHNA-octaprenyltransferase</shortName>
            <ecNumber evidence="7">2.5.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">menA</name>
        <name evidence="8" type="ordered locus">Swoo_3212</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26478"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:11173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="EC" id="2.5.1.74"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MenA family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.74" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325818.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3212"/>
    <dbReference type="EnsemblBacteria" id="ACA87482">
        <property type="protein sequence ID" value="ACA87482"/>
        <property type="gene ID" value="Swoo_3212"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3212"/>
    <dbReference type="eggNOG" id="COG1575">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043611_1_2_6"/>
    <dbReference type="OMA" id="QWIEGAR"/>
    <dbReference type="OrthoDB" id="1472516at2"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046428">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01937">
        <property type="entry name" value="MenA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004657">
        <property type="entry name" value="MenA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005355">
        <property type="entry name" value="UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="30743" checksum="C8C1EA8CA4E9DA53" modified="2008-04-29" version="1">MNPWILAIRPRTLPAAIGPLLVGNILALQLTQFSLLIACVSMLCAVLLQIAVNLANDYFDFKSGVDTEERLGPVRVTQSGLLSPTKVRNAMSLCLLLALLVGSYLIWHGGWPIAVLATAAILGALCYSGGPYPLASHGLGELAAFVFFGLVAVVGSYYLQAGETSIQAWILGAAIGFLNAAIMLVNNTRDMVTDTKAGKQTLAVRLGLGQARVLYQAFVYLPFALIIAGFFLGFLPGLPVLLAGLSLIIARKLNTDFSQSSGAELNPLLGRTAKLTMIFSALFSIGLVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN31</accession>
    <name>B1KN31_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">YidE/YbjL duplication</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4738</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAE transporter (TC 2.A.81) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327305.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4738"/>
    <dbReference type="EnsemblBacteria" id="ACA88988">
        <property type="protein sequence ID" value="ACA88988"/>
        <property type="gene ID" value="Swoo_4738"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4738"/>
    <dbReference type="eggNOG" id="COG2985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035023_2_2_6"/>
    <dbReference type="OMA" id="VYPLGMF"/>
    <dbReference type="OrthoDB" id="1458740at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006512">
        <property type="entry name" value="YidE_YbjL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06826">
        <property type="entry name" value="Asp-Al_Ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="310"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="581" mass="61313" checksum="DFE2CCDFD9DDD7BD" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNA3</accession>
    <name>B1KNA3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mutator MutT protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0299</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322949.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0299"/>
    <dbReference type="EnsemblBacteria" id="ACA84600">
        <property type="protein sequence ID" value="ACA84600"/>
        <property type="gene ID" value="Swoo_0299"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0299"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_19_2_6"/>
    <dbReference type="OMA" id="KLEYQFP"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008413">
        <property type="term" value="F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003561">
        <property type="entry name" value="Mutator_MutT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00586">
        <property type="entry name" value="mutt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="8-oxo-dGTP binding" evidence="2">
        <location>
            <begin position="39"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR603561-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR603561-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="134" mass="15165" checksum="1CB3067D8C31F1D0" modified="2008-04-29" version="1">MTDSVKKRVHVAVGVIINDKQEILLAKRLDHLHQGGKWEFPGGKVELGETVTDALKRELKEEVNLDVASSSPLMEISHDYPDKQVLLDIHLVTNFTGKARGLEQQEICWVPKKELINYEFPEANKPILDKILAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB5</accession>
    <name>B1KNB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322961.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0311"/>
    <dbReference type="EnsemblBacteria" id="ACA84612">
        <property type="protein sequence ID" value="ACA84612"/>
        <property type="gene ID" value="Swoo_0311"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0311"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_701824_0_0_6"/>
    <dbReference type="OMA" id="GERYCHV"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="164"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="46989" checksum="03F4B57885590FB4" modified="2008-04-29" version="1">MNELSIKISPTAFKHLNGAHFPLLIINDELELNSAAYLLHRYNNGTALKTVEREAKALRKFYLFCISNNIDFIGRFSKLERLTIGEIEHLHGVLSLREDTGELVSQTYFLHNWSTILRYIEFLYSFYQSRINDPHRLSTSRIVLEGMRNSFGINAKTPHNGIQNERIGLTPELQVKFLAIIDPTNENTLNPYKSEKVRWRNFCFFMTLMMGGNRKGESLGLKVRHFNLSGSSKSSKYFEIIKEDRTFDDYGRKEIPQVKTKGRKVELTPQLAEIFEYYITKIRPLFKGAKKSEYMFISIRDGKPLSALTPNMSLNDLIVQYPEFKGKLSPHILRNTFHDILENVLDVEFEGVAPIRKQQNKATIQEYAGGWTAGSKMVSHYPKGSIQRKVADLQIRLQEALLSNNGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE6</accession>
    <name>B1KNE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Urea amidolyase related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1738</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324369.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1738"/>
    <dbReference type="EnsemblBacteria" id="ACA86023">
        <property type="protein sequence ID" value="ACA86023"/>
        <property type="gene ID" value="Swoo_1738"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1738"/>
    <dbReference type="eggNOG" id="COG1984">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028967_0_3_6"/>
    <dbReference type="OMA" id="DDYAYSW"/>
    <dbReference type="OrthoDB" id="909676at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003778">
        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00797">
        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00724">
        <property type="entry name" value="urea_amlyse_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHS2" evidence="4">
        <location>
            <begin position="24"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="33817" checksum="7C2D333FD94F52B6" modified="2008-04-29" version="1">MSFDIIKCGMLSLLQDYGRYGYQHIGVTSGGPMDEHAFLWANKLLDNVANATQIEVTFGGLVLLATKPTVIAITGADLGAYINKKAVKPWRTYNISVGDTIMFNQPNTGLRSYLAVKGGFHVEPHLGSSATVVREGIGGIERNGVKLEAGDKLKYSPYTNQYFRSVSSHFIPDYSATIELGVIPSYQFDGFSKHQINIFFSSTYEISNQIDRMGYRLKGEPISYDGNGIISEGISMGAVQIPQDGQPIVLLRDRQTIGGYPKIGCVSALDCNLLAQKRSGDTITFKLIDLQHEQGRRCIFNRFFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNH5</accession>
    <name>B1KNH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RepA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1768</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324398.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1768"/>
    <dbReference type="EnsemblBacteria" id="ACA86052">
        <property type="protein sequence ID" value="ACA86052"/>
        <property type="gene ID" value="Swoo_1768"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1768"/>
    <dbReference type="eggNOG" id="ENOG5033IXT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149203_0_0_6"/>
    <dbReference type="OMA" id="QDGMNKS"/>
    <dbReference type="OrthoDB" id="1905992at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="13135" checksum="2DDE332E31791506" modified="2008-04-29" version="1">MSLTDLKRRKKKSHQDCISVDDFIEDANSYAFGKPSAVSRNRKKLRQAQLNGLDKHSTKIFKHATFSLTEDAITVLDELATQSKIAKSRLIRILIHDFFDLSDEERENVIGKGED</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI6</accession>
    <name>HSCB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Co-chaperone protein HscB homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hscB</name>
        <name type="ordered locus">Swoo_1779</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with HscA and stimulates its ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HscB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324409.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNI6"/>
    <dbReference type="SMR" id="B1KNI6"/>
    <dbReference type="STRING" id="392500.Swoo_1779"/>
    <dbReference type="EnsemblBacteria" id="ACA86063">
        <property type="protein sequence ID" value="ACA86063"/>
        <property type="gene ID" value="Swoo_1779"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1779"/>
    <dbReference type="eggNOG" id="COG1076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068529_2_0_6"/>
    <dbReference type="OMA" id="KFMAKLQ"/>
    <dbReference type="OrthoDB" id="1520143at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00682">
        <property type="entry name" value="HscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="PTHR14021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="SSF47144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000131756" description="Co-chaperone protein HscB homolog">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00682"/>
        </source>
    </evidence>
    <sequence length="174" mass="19992" checksum="6372A141D74E7720" modified="2008-04-29" version="1">MNYFELFSFTPTYQIDTALLAERYRELQRAVHPDKFANASEQDKRIAVQRTAQVNDGFSTLKDPILRAEHMLSLNGIDLKHESTTVKDTLFLMQQMEWRESLEDISDSSDPDTAISDLHESFSDYAKQIAEELSGLLSSTNEAELIQAADLIRKLKFMAKLQIELERIEDALFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNM9</accession>
    <name>B1KNM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mn2+-dependent serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324452.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1822"/>
    <dbReference type="EnsemblBacteria" id="ACA86106">
        <property type="protein sequence ID" value="ACA86106"/>
        <property type="gene ID" value="Swoo_1822"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1822"/>
    <dbReference type="eggNOG" id="COG3642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094944_0_0_6"/>
    <dbReference type="OMA" id="YWLKQPE"/>
    <dbReference type="OrthoDB" id="1505479at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="32"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="240" mass="27803" checksum="89FC8D20297BEB63" modified="2008-04-29" version="1">MPNQTFRSLVDTVLNDNKGERVVRFEHLGQVYWLKQAEKLTGAMRFLKANPKTAIQTEIETLTQLAKQGAQVPELVCFDDNFLVVADVGKTLSEWIVNPEVDQAKRLRILTDSGEALAKLHRLGLAHGRPALRDISWHDGKISFIDFEASQNSKDITYQQRRDILVYIHSLYRYLGPNHEMITPVIKAYRDAGGEHIWQEAKAWIAPWQFLYYALYPLKDIGGKDLRPIYWLLWHFKQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU9</accession>
    <name>B1KNU9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Phosphotransferase system EIIC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_3287</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325893.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3287"/>
    <dbReference type="EnsemblBacteria" id="ACA87557">
        <property type="protein sequence ID" value="ACA87557"/>
        <property type="gene ID" value="Swoo_3287"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3287"/>
    <dbReference type="eggNOG" id="COG1263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012312_1_0_6"/>
    <dbReference type="OMA" id="ETDATIM"/>
    <dbReference type="OrthoDB" id="2035550at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="20"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="409"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA87557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="488" mass="54151" checksum="88DE0FE1F0643D31" modified="2008-04-29" version="1">MATDLEHPNRYRNLLTYLQEHWFRFAQRLSQALLIPIAILPAAGVMLGLAKSPLPFIPDIVNVIMLTVGNLIFSMMPMLFAVAVAIGFCRDQGIAAFSAVFGFGVYLSSMAALADIYHLQTRALWGVETIDTGIAGGMLVGAITCLAVSQSERLRLPVVFSFFEGRRSAPLLMIPLCILLAYLFILIWPSMSAWIERLSNWVVYQKPAEAFALYGAVERLLIPLGLHHIWNAPFYLEFGQYFRDGEVVRGEVARYLAGDPLAGNLAGGYLIKMWGLPAAALAIWRCADKDQRNRVAGIMISAATACWLTGVTEPIEFAFLFVAPLLFLIHALLTGLAYWVCILLDIHHSIVFSHGVVDFTLLLGNAQRAEWFLILGPITGVLYYLIFRGSILFFDLKTPGRVVHTDGMKADIPSIVRALGGRKNILELSACLTRLRMSVKKPELIDKDKLNQLGAKGVILVGNGVQLVYGTKAESIRRLLQRYIDRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPV7</accession>
    <name>B1KPV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FMN-binding negative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325975.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3371"/>
    <dbReference type="EnsemblBacteria" id="ACA87640">
        <property type="protein sequence ID" value="ACA87640"/>
        <property type="gene ID" value="Swoo_3371"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3371"/>
    <dbReference type="eggNOG" id="COG2808">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065853_3_0_6"/>
    <dbReference type="OMA" id="ADWYASP"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PTHR35802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010372">
        <property type="entry name" value="PaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="23057" checksum="31C84F759AECA0EA" modified="2008-04-29" version="1">MHIPKTMKIESRELIHQFIEAFSFGAIISEQLEANHLPFLLQRSEGELGTLYGHFSRANQHLATQDGCTVMVILQGPHSYISPTWYVSSPAVPTWNYAAVHIHGEMKLLPVADTIKILDETVRAYEPELLNTGETLTDEYRDRLVKGVIGFKINITQMLGKQKLGQNRKPADQLGVVNGLKIQSNTDAISLLNYMKKVGVGLGETNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPX3</accession>
    <name>B1KPX3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325991.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87656">
        <property type="protein sequence ID" value="ACA87656"/>
        <property type="gene ID" value="Swoo_3388"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3388"/>
    <dbReference type="HOGENOM" id="CLU_943004_0_0_6"/>
    <dbReference type="OrthoDB" id="2152248at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="295" mass="33197" checksum="4A38470CB8042D0A" modified="2008-04-29" version="1">MVGELKFKMLMAAVLLLSGCSDELTLVFKKDVDLQEKALQEIRESLDGVARINHYEWHAQTKGFLQQPALTIKFKAVDGNDNYSVAQVSELLVGQFSYSEKDVSITRTITEDREEFLEKMGVETGQKFTTNLYWGRAKANVFYTEESSRLFGGRDNRFVDRNFFCAIEVPMEDALPSVSFSYASDNPNPIFAQLMKNMVLEAKNETTIDGLPVNEGWENLEIDNDRKVAFIMFEYLGEMNNQVELVLPVSTSTPNNVSKRDCLDAMKEKLGSTLYGVLGEVSAMDNVLTVGEPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ02</accession>
    <name>B1KQ02_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4866"/>
    <dbReference type="EnsemblBacteria" id="ACA89115">
        <property type="protein sequence ID" value="ACA89115"/>
        <property type="gene ID" value="Swoo_4866"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4866"/>
    <dbReference type="eggNOG" id="COG1668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022118_2_0_6"/>
    <dbReference type="OMA" id="KDAFRDR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="387" mass="42245" checksum="E64D2703AC4D2704" modified="2008-04-29" version="1">MISNIITMVRKELIDAARDKRSVMAGLYYAIGTPLLMCGMFMLLIGQMTSPEDLNIKIENGNNAPDLVKYLSSQGITHGDSLSINENGDKLDVKDIRLVISDDYAAQMAKGLSAEITLIADNSNEKLQNSIRRLERNLQAYSSEMGSLRLIARGIDPRVVQPIKVNVEDEATPDSKGGVILGVATMTMIYAVFISGMNLAIDTSAGERERNSLALLLSHPVSTRNIVLAKVIAVTVFAMVGLLLTLIISKISYAFVPWQELGFTVSISTEFILLMLLTGLPIALMAASLQLFVSFMAKTFKEAQSYLTLVLIVPMMLSMAASYNIAPDTLQWLPVSGQQQALIAFIKGREIPMLQLLLSSLTTFIIAIGLAFGMERSLKSEKIVFGL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ36</accession>
    <name>ATPA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="1">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpA</name>
        <name type="ordered locus">Swoo_4900</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327466.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ36"/>
    <dbReference type="SMR" id="B1KQ36"/>
    <dbReference type="STRING" id="392500.Swoo_4900"/>
    <dbReference type="EnsemblBacteria" id="ACA89149">
        <property type="protein sequence ID" value="ACA89149"/>
        <property type="gene ID" value="Swoo_4900"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4900"/>
    <dbReference type="eggNOG" id="COG0056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010091_2_1_6"/>
    <dbReference type="OMA" id="LQAPGVM"/>
    <dbReference type="OrthoDB" id="837522at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0139">CF(1)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000143437" description="ATP synthase subunit alpha">
        <location>
            <begin position="1"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="1">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <sequence length="513" mass="55491" checksum="3E35F688BE0E5189" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ69</accession>
    <name>B1KQ69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein-disulfide isomerase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323073.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0426"/>
    <dbReference type="EnsemblBacteria" id="ACA84724">
        <property type="protein sequence ID" value="ACA84724"/>
        <property type="gene ID" value="Swoo_0426"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0426"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_528814_0_0_6"/>
    <dbReference type="OrthoDB" id="991700at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767553" evidence="3">
        <location>
            <begin position="24"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="4">
        <location>
            <begin position="128"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="515" mass="57917" checksum="6A9FB555128CE20F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQF4</accession>
    <name>B1KQF4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="11" type="ordered locus">Swoo_0512</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323157.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0512"/>
    <dbReference type="EnsemblBacteria" id="ACA84809">
        <property type="protein sequence ID" value="ACA84809"/>
        <property type="gene ID" value="Swoo_0512"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0512"/>
    <dbReference type="eggNOG" id="COG1158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016377_4_3_6"/>
    <dbReference type="OMA" id="TRLCRAH"/>
    <dbReference type="OrthoDB" id="1619125at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01128">
        <property type="entry name" value="rho_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="10">
        <location>
            <begin position="48"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA-binding 1" evidence="8">
        <location>
            <begin position="61"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA-binding 1" evidence="8">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA-binding 1" evidence="8">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA-binding 2" evidence="8">
        <location>
            <begin position="284"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="181"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="RNA-binding 2" evidence="8">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="421" mass="47137" checksum="56AB1E645A701AEC" modified="2008-04-29" version="1">MNLSELKDKSISDLVLLAQEMKVENTARARKQDIIFSILKAHAKSGEDIFGGGVLEILQDGFGFLRSADASYLAGPDDIYVSPSQIRRFSMRTGDTIFGKIRPPKEGERYFALLKVSEVNFDKPENSRSKILFENLTPLHAEERIRMERGNGSTEDITSRILDLCSPIGKGQRGLIVAPPKAGKTLLLQNMAQSITYNNPDVVLMVLLIDERPEEVTEMQRMVKGEVIASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVVILLDSITRLARAYNTVIPSSGKVLTGGVDANALHRPKRFFGAARNIEHGGSLTIIATALVDTGSKMDEVIYEEFKGTGNQELHLSRKAAEKRVFPAIDFNRSGTRREEKLTTPDELQKMWILRKILNPMDEVTGMEFLIDKLAMTKTNDEFFTAMKRAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQG5</accession>
    <name>B1KQG5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324550.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1920"/>
    <dbReference type="EnsemblBacteria" id="ACA86204">
        <property type="protein sequence ID" value="ACA86204"/>
        <property type="gene ID" value="Swoo_1920"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1920"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_2_6"/>
    <dbReference type="OMA" id="WAGPGFR"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="165" mass="18655" checksum="89DBDD5480581C0C" modified="2008-04-29" version="1">MKLISVAQEHIRQMMLWFDDKDSLYSWAGPGFRYPFTYDSFIEDLNLDALISFSLVNDTGELVGFGQCYRRNGKCHLGRLVIAPHFRGQTCQIAPSKTMKVSHYLILALSEQGCEVLELPLVSGSVSLFVLNHNLPALNLYLSLGFVESQYPEAIPIDNCLYMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQG9</accession>
    <name>B1KQG9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324554.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1924"/>
    <dbReference type="EnsemblBacteria" id="ACA86208">
        <property type="protein sequence ID" value="ACA86208"/>
        <property type="gene ID" value="Swoo_1924"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1924"/>
    <dbReference type="HOGENOM" id="CLU_1495226_0_0_6"/>
    <dbReference type="OrthoDB" id="2104028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="180" mass="20528" checksum="6149C3981EC65ECB" modified="2008-04-29" version="1">MLEYFSLFNRIEWALIIIAFAVSAKSANIRWLTGTLIVLKTIDVLVIDIILQWGGFYYLAISFYDVVIIAMILNRQKTASWIAGLNIPVLSRLALGSAQYYKLTSNEICLILLYLASILVNLLSLSERLVRKYTEFEPMFFYNIYPEAKLTLTTLSILILCSVAINGANNLYRDRKGQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ4</accession>
    <name>B1KQJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324579.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1949"/>
    <dbReference type="EnsemblBacteria" id="ACA86233">
        <property type="protein sequence ID" value="ACA86233"/>
        <property type="gene ID" value="Swoo_1949"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1949"/>
    <dbReference type="eggNOG" id="ENOG502ZUTC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_197539_0_0_6"/>
    <dbReference type="OMA" id="MYAMAED"/>
    <dbReference type="OrthoDB" id="1977743at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021811">
        <property type="entry name" value="DUF3389"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11869">
        <property type="entry name" value="DUF3389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="73" mass="8020" checksum="3AC6382B1C1A9728" modified="2008-04-29" version="1">MVIDFSQGKIILTPFEIQIKLSTSGSGMYAMAEDLNFIDDALIINADAGSVKWSLRLDSIEQLNMIRETLGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQS2</accession>
    <name>B1KQS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326013.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3410"/>
    <dbReference type="EnsemblBacteria" id="ACA87678">
        <property type="protein sequence ID" value="ACA87678"/>
        <property type="gene ID" value="Swoo_3410"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3410"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1004351_0_0_6"/>
    <dbReference type="OMA" id="KQPLAMT"/>
    <dbReference type="OrthoDB" id="1265119at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767302" evidence="1">
        <location>
            <begin position="23"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="277" mass="31151" checksum="6F0E9B785046EB69" modified="2008-04-29" version="1" precursor="true">MDYKQPLAMTLLSLAVSSSCFAADYQNVKDIPFKDSNFKACVLAQTTEDPAAITKLICRQMKINQVDELSHFPALERLWISGPQLKEVDLSGNLKLTELSITKGKLTQLDLSKNSQLQELNISFNQISDLDLTHNPKLTDISVVANRLTELDLSQNSALKYLWAKENQFTSLDFSHNSALVQVGLTSNQISTIDVSKNSELNRLGLMYNQLTKLDVSYNSKLTKLYLTDNKLTHIDISQNPKLRDLWATGNPLEQLDISKNPKLDDYEVDEGIKISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQX4</accession>
    <name>B1KQX4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3464</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326065.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3464"/>
    <dbReference type="EnsemblBacteria" id="ACA87730">
        <property type="protein sequence ID" value="ACA87730"/>
        <property type="gene ID" value="Swoo_3464"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3464"/>
    <dbReference type="eggNOG" id="COG2020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065200_4_2_6"/>
    <dbReference type="OMA" id="FICKTSI"/>
    <dbReference type="OrthoDB" id="1734625at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="155" mass="17530" checksum="27A4D5518533054D" modified="2008-04-29" version="1">MEKDVNGAGVKIPPPAIFILFMLLAYLNGLFVPIAITFAAPITYLGLGILLAGLFLLLYLVYQFRKAKTAVEPWQPTSSLIKTGIYAYSRNPIYLAFCTFPVGLGLYLSDLWLISSVLPSCIGVYYVAIRAEEAYLTRKFGDEYLRYQQQVRRWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQX9</accession>
    <name>B1KQX9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3469</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0382 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326069.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3469"/>
    <dbReference type="EnsemblBacteria" id="ACA87735">
        <property type="protein sequence ID" value="ACA87735"/>
        <property type="gene ID" value="Swoo_3469"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3469"/>
    <dbReference type="eggNOG" id="COG2363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096548_3_1_6"/>
    <dbReference type="OMA" id="QFYHTFA"/>
    <dbReference type="OrthoDB" id="1985942at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="PTHR43461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14073" checksum="3429A7E31A56FE96" modified="2008-04-29" version="1" precursor="true">MRKGFLLLAALSGFISVALGAFGAHGLKNVASPEMIAIFNLGVEYQFYHTFALIAVAFAGHWLSSRLLDWAGYLFIAGMLLFSGSLYLYALLGTKWTGPITPMGGVCFLVGWLLIALAVWRNRVVELND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ3</accession>
    <name>B1KQZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobalamin synthesis protein P47K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326083.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3483"/>
    <dbReference type="EnsemblBacteria" id="ACA87749">
        <property type="protein sequence ID" value="ACA87749"/>
        <property type="gene ID" value="Swoo_3483"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3483"/>
    <dbReference type="eggNOG" id="COG0523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_1_2_6"/>
    <dbReference type="OMA" id="VGWRFSP"/>
    <dbReference type="OrthoDB" id="1267701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="1">
        <location>
            <begin position="7"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="351" mass="38499" checksum="15AB47A7286F2081" modified="2008-04-29" version="1">MILKPIPTNVITGFLGVGKTSFIKQLLATKPEGETWAILVNEFGEVGIDGALLSGSGESIEIREVAGGCLCCAASVPMQVAINQLIAKAKPDRLLIEPTGLGHPQEVVKLLSQSHYQNVIALKSTVCLVDARKVSDERYSGHDIFNQQLRVADIVLATKSDLYRDREFQELTDYVEHAFPSKGPKQSTFFLLSMLANAQTSLSAQLLASLDSAAKLPKKVFSPQKSLLTPEPISVFEIEPALVEPELDERGVLVKHNSGEGFYSCGWVFDLSYEFNFDEVINFIKSLDVTRIKAVLITDEGIAGFNVIDGEMSVVELDDTMDSRLEIISLSTLEVDKLEAQLFAVSKRISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR24</accession>
    <name>B1KR24_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323189.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0545"/>
    <dbReference type="EnsemblBacteria" id="ACA84841">
        <property type="protein sequence ID" value="ACA84841"/>
        <property type="gene ID" value="Swoo_0545"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0545"/>
    <dbReference type="eggNOG" id="COG0511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_3_1_6"/>
    <dbReference type="OMA" id="YESPGVG"/>
    <dbReference type="OrthoDB" id="1938042at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="76"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17004" checksum="0A7BFCF1251AC2A0" modified="2008-04-29" version="1">MDIRKIKKLIELVQESGIAELEVTEGEESVRICQHRDQTSASQTTQQIHTLANSPQVDNSQDDASDVDQVTDFDEKNTVISPMVGTFYLSPAPEAEPLCKVGQRVEQGDPICIIEAMKMMNQIEALRSGIVSKILVESGDGVEFDQALIIIEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR47</accession>
    <name>B1KR47_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323212.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0568"/>
    <dbReference type="EnsemblBacteria" id="ACA84864">
        <property type="protein sequence ID" value="ACA84864"/>
        <property type="gene ID" value="Swoo_0568"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0568"/>
    <dbReference type="eggNOG" id="COG4269">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049287_0_0_6"/>
    <dbReference type="OMA" id="FRIWIVN"/>
    <dbReference type="OrthoDB" id="944442at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010295">
        <property type="entry name" value="DUF898"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05987">
        <property type="entry name" value="DUF898"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="43306" checksum="F50014DA9C472BB1" modified="2008-04-29" version="1">MTRTNTDLSNTQHSFNFHGNATEFFGIWIVNILLTIVTFGIYSAWAKVRTNNYFYGNTELDGDRFEYLAKPMQILIGRIIAVVALIAWTILSGVHPVAAIACGALLTLAIPYLSVRNIRFDARITRFRNVRFNFEGSYSGAYLNILAKPLAAYAIIIGSSMGFSALLMESNPAIAVIGGILLFTLTGVFGYAWVMTGMASYVVNGYRYGGKQFSAELDMGEYAKIAALAGALFLGSMILGFLIILGFGMFDTIASLFSGEPLDPTNQASSFFALFIGYIYMFFIGFVIAAFIKTRIRNYLFSKTQIDDKLQLVSNMTLGGYLSLIITNLLIVVFTFGLGRAWTDIRRAQYMASITQVEGDLALMSVRDHNQETNNAIADEMVDAFDINLNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR56</accession>
    <name>B1KR56_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane adhesin like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0577</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0577"/>
    <dbReference type="EnsemblBacteria" id="ACA84873">
        <property type="protein sequence ID" value="ACA84873"/>
        <property type="gene ID" value="Swoo_0577"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0577"/>
    <dbReference type="eggNOG" id="COG4932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_232784_0_0_6"/>
    <dbReference type="OMA" id="QALDIQC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2047"/>
            <end position="2069"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="3">
        <location>
            <begin position="565"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1377"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1788"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1952"/>
            <end position="1979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2000"/>
            <end position="2037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1377"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1400"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1952"/>
            <end position="1969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2017"/>
            <end position="2033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="2074" mass="219636" checksum="18EE1C41F6A0D7A1" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR93</accession>
    <name>B1KR93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coenzyme F390 synthetase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324646.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2016"/>
    <dbReference type="EnsemblBacteria" id="ACA86300">
        <property type="protein sequence ID" value="ACA86300"/>
        <property type="gene ID" value="Swoo_2016"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2016"/>
    <dbReference type="eggNOG" id="COG1541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035301_0_0_6"/>
    <dbReference type="OrthoDB" id="839891at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="185"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="452" mass="50521" checksum="44D0E903C0AD02EC" modified="2008-04-29" version="1">MSDQVGITINKLSAVLKRRIEISNDVMSTLSLSRDEFKLWQELALLNNVKHACLHSPFYQNHIPKQLAQEFINGDLTRFSKLPFTTRDDLMNQYPLGLLSVPKEQVVRFNESSGTSNGKPISAYFTQKDWLTNNNTVAHFLSSVLTSKDCVALAVPYELAGIGQDLDRSIELLNCSVVALGALTKFCPPERMVNILKTAGVTTLICSGTRALYLADVAKEQGICPKSELKVDKILFAGEGASKAKRRLLEETWGAKVYAMYGMTETNTLAMFCTENRLHLIENRNYFEVINPTTGSLQERGEKGELVVTSLSSEAMPLIRYRTGDFCTIDDLPCRCGSPFRVLNHMGRTTDLIMVGSKPISQLQLEDAIMMHLPSSPYYFSFKAKSDKLLIGLTSNNILDTVHSNIAHEILRRFEVSVEFTSIAKEKFVHALRTAAKPTMNNFLLDDEDANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRE0</accession>
    <name>B1KRE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324692.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2063"/>
    <dbReference type="EnsemblBacteria" id="ACA86347">
        <property type="protein sequence ID" value="ACA86347"/>
        <property type="gene ID" value="Swoo_2063"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2063"/>
    <dbReference type="eggNOG" id="ENOG5032Z4S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137390_1_1_6"/>
    <dbReference type="OMA" id="KWNRAAI"/>
    <dbReference type="OrthoDB" id="2016615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021866">
        <property type="entry name" value="SpoIIAA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038396">
        <property type="entry name" value="SpoIIAA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11964">
        <property type="entry name" value="SpoIIAA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="121" mass="13680" checksum="7703F53AA662EEAC" modified="2008-04-29" version="1">MLELLNGFDHDTVAIRATGVVTGKDYDQHLMPVIEDKLKDHASIKLWYEFDDKFEGVTVGTLWDDAKIGLFHLNDFYRVAIITDSQLVAGMANTLAYMIPCPVKVFARSEASEATHWMKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRH6</accession>
    <name>B1KRH6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324728.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2099"/>
    <dbReference type="EnsemblBacteria" id="ACA86383">
        <property type="protein sequence ID" value="ACA86383"/>
        <property type="gene ID" value="Swoo_2099"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2099"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_5_6"/>
    <dbReference type="OMA" id="MVDRIPD"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="36504" checksum="53A589E1439A42BB" modified="2008-04-29" version="1">MRAFDFDLKSLQVFVIAAQTGSMTETARRLGLTQSSVSQTLSMLEKNLKVELLDRTVRPLGLTIAGRYFFDQSSHLLSQAEQTQKVFSQGAFEQLHLVRIAMVDSLATSLGKPLIEAVKKRTENWTLSTGRSHMHADALMSRQVDIIISDDALEDSDELSRYPILSEPFVLVSPLNVGWEHKEGSLVSDIHRLHQELDFVRYTHDSLIGTSIERYLRRLGIKPAMRLQLDNTFAVLSMVASGLGWTITTPLCLYQSGIPLAQVKCQPLPANYGFKRRLTLVTRRHELSDLAEQMARDSCEIMSECFLPELEKDLPWLVADIDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRI8</accession>
    <name>B1KRI8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease D</fullName>
            <shortName evidence="4">RNase D</shortName>
            <ecNumber evidence="4">3.1.13.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rnd</name>
        <name evidence="6" type="ordered locus">Swoo_2111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.</text>
            <dbReference type="EC" id="3.1.13.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase D family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.5" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324740.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2111"/>
    <dbReference type="EnsemblBacteria" id="ACA86395">
        <property type="protein sequence ID" value="ACA86395"/>
        <property type="gene ID" value="Swoo_2111"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2111"/>
    <dbReference type="eggNOG" id="COG0349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042387_0_1_6"/>
    <dbReference type="OMA" id="FMRVDTF"/>
    <dbReference type="OrthoDB" id="1462689at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033890">
        <property type="term" value="F:ribonuclease D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042780">
        <property type="term" value="P:tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01899">
        <property type="entry name" value="RNase_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006292">
        <property type="entry name" value="RNase_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01388">
        <property type="entry name" value="rnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="HRDC" evidence="5">
        <location>
            <begin position="211"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="369" mass="41704" checksum="200814849F34D077" modified="2008-04-29" version="1">MLAFQYIDDDASLAKLVSQYRESQLLVLDTEFVRTRTFYARLGLIQAYDGKTLALIDPVAVSDLSGFWSLLTEPSITTILHSCSEDLEVFARNGQCQPVKLFDSQIAAALCGFGHGLGYAKLVEQTLNIPLDKGESRTDWMKRPLSEAQLNYAANDVYYLYQLYPQLVEKLEEQNRLGWVFEEGERMTQGRLSPPDLELAYLRVKNAFQLSPKQLAYLKVLAKWRLSKALSRDLAVGFVVKDHGLIGLAKKQPKNSSELYKMIELTEQEKRVHGKDLIRLLATADLDNLPDAIDVLALKTGYKSSFKTIKQCLSELSERHEVPIELLGSKRHIHEYLEWLWAGKVGDKPLLLSGWRETLVSAPLSALSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK5</accession>
    <name>B1KRK5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3506</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326103.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3506"/>
    <dbReference type="EnsemblBacteria" id="ACA87770">
        <property type="protein sequence ID" value="ACA87770"/>
        <property type="gene ID" value="Swoo_3506"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3506"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_28_3_6"/>
    <dbReference type="OMA" id="VCKKFMT"/>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="215"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="383"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="428" mass="47300" checksum="24D3687A186E9C0B" modified="2008-04-29" version="1">MKFSAFDLSPLILDAVEVCGYQQLTQVQSKVIPVAVTGCDLMACAETGTGKTAAFALPLLQKLLDEFLDRSALRGLILTPTRELAIQVADNISRYSQFTSLKTLAVYGGANMNPQRKALNAGVDILVATPGRLFDFIGQHGLDLSSVTSLVIDEADRMLDMGFVRDIERVKGLVARQHVTHFFSATYSDDVKCLAQKMLCDPTWINVATSKSASSVEQEVYLVDKRRKAELLSELVGRNNWQQVLVFASSKESAEHIQKELKLDGLKSAVFHGDKTQGARNRALEEFKSGALRVLVATDVAARGLDIHALPLVVNIELPFDAQDYIHRIGRTGRAGLTGHAISFVCPSDEKMLEEIEALIERKLPRIVVPGYEQGTALPARYRDSVEVAPNKKRVERRKGKPAGRKEQTRRTKSTSDKSSYSSRRSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRP3</accession>
    <name>B1KRP3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoserine phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_3544</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + O-phospho-D-serine = D-serine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24873"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58680"/>
            <dbReference type="EC" id="3.1.3.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-serine = L-serine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="3.1.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326141.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3544"/>
    <dbReference type="EnsemblBacteria" id="ACA87808">
        <property type="protein sequence ID" value="ACA87808"/>
        <property type="gene ID" value="Swoo_3544"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3544"/>
    <dbReference type="eggNOG" id="COG0560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036368_4_0_6"/>
    <dbReference type="OMA" id="CINEPDL"/>
    <dbReference type="OrthoDB" id="1755462at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00029">
        <property type="entry name" value="phosphoserine_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="active site" description="Nucleophile" evidence="14">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR604469-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA87808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="35832" checksum="FDCA23562A99961A" modified="2008-04-29" version="1">MESLNHVSLFSWLKEEQTLTFNAQTLSISRHLESELPNGAARYRCVYAEQSVESELARLLAALSQPVSLAYIVRKNALHCIELRLDKPLNETEIKQYALIDGVEFFSISPNQAVLNRCGLLVMDMDSTAIEIECIDELAVMAGVGEAVAEVTERAMQGELDFEESLRARVAQLKDADEAIIKTLCDKLPLMPGLTDMVTELQSYGWRLVVASGGFTPFVGHLKQLLDLDAAYANELVIEGGKLTGQVTGQVVDAQFKADTVERCAQAWEIPKGQRLAIGDGANDIPMIEIADFGIAYHAKPKLEAAADVAIKQLDLKVLPYLLQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="108" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX6</accession>
    <name>B1KCX6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">DNA gyrase subunit B</fullName>
            <ecNumber evidence="4 12">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gyrB</name>
        <name evidence="14" type="ordered locus">Swoo_0004</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4 12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322654.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0004"/>
    <dbReference type="EnsemblBacteria" id="ACA84305">
        <property type="protein sequence ID" value="ACA84305"/>
        <property type="gene ID" value="Swoo_0004"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0004"/>
    <dbReference type="eggNOG" id="COG0187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006146_4_1_6"/>
    <dbReference type="OMA" id="LWETTMH"/>
    <dbReference type="OrthoDB" id="205481at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041423">
        <property type="entry name" value="GyrB_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18053">
        <property type="entry name" value="GyrB_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01059">
        <property type="entry name" value="gyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="13">
        <location>
            <begin position="419"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA84305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="805" mass="90040" checksum="DA05AC1B12A0001A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDC9</accession>
    <name>B1KDC9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323277.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0634"/>
    <dbReference type="EnsemblBacteria" id="ACA84930">
        <property type="protein sequence ID" value="ACA84930"/>
        <property type="gene ID" value="Swoo_0634"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0634"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_8_0_6"/>
    <dbReference type="OMA" id="QCTRTHK"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="18296" checksum="921074523F02C8AA" modified="2008-04-29" version="1">MSASEHDSKREDEVSLEMEQFFPFQLTQLQARVSDSIADIYTGHFALSKHEWRIVAVLGAGQSLSAKDIGLMINLEKMQTSRAIAKMLDRSLLMKDSHKHDRRSSLLKLSPEGIKIHQELAPMILAREQALMSILSSYEQVKLSQMFKKLMSRADELLHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDH8</accession>
    <name>B1KDH8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323326.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0683"/>
    <dbReference type="EnsemblBacteria" id="ACA84979">
        <property type="protein sequence ID" value="ACA84979"/>
        <property type="gene ID" value="Swoo_0683"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0683"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1160451_0_0_6"/>
    <dbReference type="OMA" id="INAWLQI"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="27871" checksum="B847EF39ADF8C49E" modified="2008-04-29" version="1">MTIGKQIKHFRAERNFSQPELAELAGIEQSYLSKLENDKSIPSNEIFRNLLSALSVNTQEFIDAIDINENKQQLNQIPDIEQLLSQKDKMKFQNIRRYLYISSALIILGLTLFYTGSSKQLFNETRYQSESSGVALADEPDDIFSSWRNRMDTNGEDGRQLMRAKRLEMANREDTHYLVFREYKGQGFMMDVTGGKRHYRLDKEEQIPRQINAWLQIFGVLLLCSGIMGFVLERRLSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDK3</accession>
    <name>B1KDK3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lytic murein transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324745.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2116"/>
    <dbReference type="CAZy" id="GH103">
        <property type="family name" value="Glycoside Hydrolase Family 103"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86400">
        <property type="protein sequence ID" value="ACA86400"/>
        <property type="gene ID" value="Swoo_2116"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2116"/>
    <dbReference type="eggNOG" id="COG2951">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035402_0_1_6"/>
    <dbReference type="OMA" id="WAYEVRA"/>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043426">
        <property type="entry name" value="MltB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011970">
        <property type="entry name" value="MltB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031304">
        <property type="entry name" value="SLT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163">
        <property type="entry name" value="PTHR30163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13406">
        <property type="entry name" value="SLT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02283">
        <property type="entry name" value="MltB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLT_2" evidence="1">
        <location>
            <begin position="33"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="329" mass="36993" checksum="721156930AA02760" modified="2008-04-29" version="1" precursor="true">MTGINLGAISATFVIAIGLQHNVFAQDVKPTSSFQQFLSNLKQEAREKGIAEQTLESSFSNIKLFRAAQDSSKTAEKSMTTLETYIPERVPEWKVDKARAQFLQYKTELKAIGDKYGVQPRFLVALWALESDFGEAISQYPLLSVTASKAFDKPERVDYQEEVFATLQILEQESLQVSELKSSSKGLVGQPLFLPSQYLLYAQDGDGDGKIDLWGNPQDIFASLANYLKQVGWKGEQTWGRQVLLPENFDVNDSSNGISKTFSQWGELGISRYNGKALPNRDDMLVSLIMPDGAKGRAYLVYDNYRTLIKRMDSDYQALSVTYLSERIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDT6</accession>
    <name>B1KDT6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucan 1,4-alpha-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2201</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324827.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2201"/>
    <dbReference type="CAZy" id="GH15">
        <property type="family name" value="Glycoside Hydrolase Family 15"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86483">
        <property type="protein sequence ID" value="ACA86483"/>
        <property type="gene ID" value="Swoo_2201"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2201"/>
    <dbReference type="eggNOG" id="COG3387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010471_0_0_6"/>
    <dbReference type="OMA" id="RWTSSAK"/>
    <dbReference type="OrthoDB" id="99080at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004339">
        <property type="term" value="F:glucan 1,4-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07430">
        <property type="entry name" value="GH15_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015220">
        <property type="entry name" value="Glucodextranase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09137">
        <property type="entry name" value="Glucodextran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucodextran_N" evidence="3">
        <location>
            <begin position="46"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_15" evidence="2">
        <location>
            <begin position="367"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="840" mass="92408" checksum="53E022C4A0F3F1C3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU9</accession>
    <name>B1KDU9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326283.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87951">
        <property type="protein sequence ID" value="ACA87951"/>
        <property type="gene ID" value="Swoo_3691"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3691"/>
    <dbReference type="eggNOG" id="ENOG5033132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1853862_0_0_6"/>
    <dbReference type="OMA" id="NVMRIEY"/>
    <dbReference type="OrthoDB" id="1718288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="148" mass="17177" checksum="B311F5C3778E99C4" modified="2008-04-29" version="1" precursor="true">MIIFAIFVWGLIPSSLLAEPAPLEIKKVKPKSSDRYINAVHKEIVTKTDDLNKIRYAILEGMLTTKGIAWLYDGEGEGYILARFTYRGDTNVMRIEYNQSLVQLKYHDALGDYECKNLIDDICYKNGRGYYNYIKNLRKSIARQLMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDZ8</accession>
    <name>B1KDZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3741"/>
    <dbReference type="EnsemblBacteria" id="ACA88000">
        <property type="protein sequence ID" value="ACA88000"/>
        <property type="gene ID" value="Swoo_3741"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3741"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_2_2_6"/>
    <dbReference type="OMA" id="GVTICHG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764734" evidence="1">
        <location>
            <begin position="36"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="93"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="444" mass="47064" checksum="E2E5492FF10ADA69" modified="2008-04-29" version="1" precursor="true">MKNNNNRAAKLTPLSRTSLLLAGLTTLALATPAMAANITVIHAGELLVTPGNKPLKQQTLVIENGTIKDVKPGYLAAKTFSDNVQVIDLKEHFVMPGLMDMHVHLQGELSPKNDSEKLRMSDAEVAIRSAYFAKKTLIAGFTTVRDLGAKPEQIYALRDGIERGWVDGPRIIASGGVSVTGGHGDVDGMSPDLLEKYTSKTICDGPYDCRSATRRAIKFGADVIKITSTGGVLSDTNTGTGQQMADDELKEIVDTAHGLGRKVASHAHATQGINAALRAGVDSIEHGSYADKESIKLLKKNGAYLVPTLLAGDTVVGMAKTSDFMSEDIKAKAERVGADMTANFIAVHQAGVKIAYGTDSGVSQHGTNAREAVLMHQAGMSSSDILKSATVNGADLIDMSDELGTLEVGKFADIIATDTSPLEDIEALLDVDFVMKGGKVYKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE17</accession>
    <name>B1KE17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323350.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0708"/>
    <dbReference type="EnsemblBacteria" id="ACA85003">
        <property type="protein sequence ID" value="ACA85003"/>
        <property type="gene ID" value="Swoo_0708"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0708"/>
    <dbReference type="eggNOG" id="ENOG50332WW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1089471_0_0_6"/>
    <dbReference type="OrthoDB" id="1784230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="255" mass="29752" checksum="328C5B5A99E0A5D1" modified="2008-04-29" version="1">MTRPSYKVVLSDKLFSIYKKASLPCLLRAKERKAYDLLMGNIELDILTNAAQVQRCKDDHNLPEEVYNDLYPILLNLDDQKDLSLEQLSKETLFKLIVTIADGENSPPFFNLKKQHIKRNYTLSCLHDEEREPLKDYLVCLLQGANKVLIHDKYFSSEDDNKQIFTFLPDKDIIIQYVENGERSNGRFVRDICGANAKWKVEQCDTTQAEFNRFARSHDRYLIINEEIELTLTSGFSYIWNKEKEITCVVRELLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE75</accession>
    <name>B1KE75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323408.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0766"/>
    <dbReference type="EnsemblBacteria" id="ACA85061">
        <property type="protein sequence ID" value="ACA85061"/>
        <property type="gene ID" value="Swoo_0766"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0766"/>
    <dbReference type="eggNOG" id="ENOG502Z8X1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107033_0_0_6"/>
    <dbReference type="OMA" id="FGIIWVG"/>
    <dbReference type="OrthoDB" id="1707319at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="22952" checksum="951DE586CF2AF083" modified="2008-04-29" version="1">MNNLQKIGGIAALFEAAIYIAAFVFFGAFWDYPSSAGDAQKFIFLTNNQLILSIVNLTMYVVFGLFLAILVLALHQRMKTKAPALSQLASVFGIIWVGLVIASGMIANIGLAAVIDLSTSNIEQAKTLLVVVNTIVEGLGGGNEVVGGLWVLLLSIAGLKINELPKLLHYLGLFIGSVGILTIYPAEILTEIFGLGQIIWFSWLGVAMLKTPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA8</accession>
    <name>B1KEA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0799</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323441.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0799"/>
    <dbReference type="EnsemblBacteria" id="ACA85094">
        <property type="protein sequence ID" value="ACA85094"/>
        <property type="gene ID" value="Swoo_0799"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0799"/>
    <dbReference type="eggNOG" id="COG3614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_59_6"/>
    <dbReference type="OMA" id="LPHTRDC"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="5">
        <location>
            <begin position="71"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="390"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="538" mass="60768" checksum="163AC1A9F9592D92" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEC4</accession>
    <name>B1KEC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324846.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2221"/>
    <dbReference type="EnsemblBacteria" id="ACA86502">
        <property type="protein sequence ID" value="ACA86502"/>
        <property type="gene ID" value="Swoo_2221"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2221"/>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_656630_0_0_6"/>
    <dbReference type="OMA" id="PDSRLKH"/>
    <dbReference type="OrthoDB" id="454034at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021953">
        <property type="entry name" value="DUF3570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12094">
        <property type="entry name" value="DUF3570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="486" mass="54915" checksum="8E039B57CB0FBBED" modified="2008-04-29" version="1" precursor="true">MRKKRSSIQESSTQKSSTQRSSAFELASGASDKHQCKRYRNINKSLTIASFALFSAPVMATEIDDSKDMEEADKTSISLPTIASEKKLEVTKIETALLYYQEPDRVTAAEGIFNLQASYGDKSELEGKLLLDTLTGASPNGAAPQQQQQTFTRPSGNGVYYAKNGETPLDDTFKDTRLQLNGNWTETLSNTDKVNLGFHLSREYDYTSLGVNSGAERSFNRGNSAVNLAFGYYYDIIDPVGGRPVSWAPMLFRDDFSSQSEFKQAFDKTRDLSSSIKQTFDLSVGFTQLLNRYWLVQGNYSFSYLDGYMTDPYKIISQIDERGTAQGYLYENRPDTRYKQSVFLLTKGALETGVVDLSYRYSADDWGIDSHTVETHYRYQFTASLYGQIHLRYYRQSAVDFYHAFLPELDELPEYGSADSRLGKLTAYTFGIKFGHKLQGGTKFSYRLELYQHRPQDNGDERVGQLAHLGLYEQVNAVIAQIGFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEJ7</accession>
    <name>B1KEJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324917.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2296"/>
    <dbReference type="EnsemblBacteria" id="ACA86575">
        <property type="protein sequence ID" value="ACA86575"/>
        <property type="gene ID" value="Swoo_2296"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2296"/>
    <dbReference type="eggNOG" id="ENOG503315X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174545_0_0_6"/>
    <dbReference type="OMA" id="CNKRISS"/>
    <dbReference type="OrthoDB" id="1971148at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="11466" checksum="D0491700DFE8FFA4" modified="2008-04-29" version="1">MALIECPSCNKRISSKATECQHCGSQLSGDNQVLSKISHIKRSAQLVNQGLLSMSLFIAGVVVWFWGGEPAEGLRSYIGGACFVLGFVGYLVTRLQIVLHERKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEK7</accession>
    <name>B1KEK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326354.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3763"/>
    <dbReference type="EnsemblBacteria" id="ACA88022">
        <property type="protein sequence ID" value="ACA88022"/>
        <property type="gene ID" value="Swoo_3763"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3763"/>
    <dbReference type="eggNOG" id="ENOG5032WKV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150686_0_0_6"/>
    <dbReference type="OMA" id="FNQNAIY"/>
    <dbReference type="OrthoDB" id="1402002at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021710">
        <property type="entry name" value="DUF3293"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11697">
        <property type="entry name" value="DUF3293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16788" checksum="40C4EB0C6AE874D5" modified="2008-04-29" version="1">MNQSNNQLWQCYQNARFLFTQPLSCEVSFAIITAHNPKGEILSACQNRLLDRQLQHEIEQLRQPYRAMVGTSVDHSHMEKSWAVSTTKDSALHLGRMFNQNAIYYVEHDKLQLVPCLLSPLHHKEQLIGHFSSRVSLVNELPDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEM9</accession>
    <name>B1KEM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3785</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326375.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3785"/>
    <dbReference type="EnsemblBacteria" id="ACA88044">
        <property type="protein sequence ID" value="ACA88044"/>
        <property type="gene ID" value="Swoo_3785"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3785"/>
    <dbReference type="eggNOG" id="COG1115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024867_1_2_6"/>
    <dbReference type="OMA" id="VSMTQVF"/>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="457" mass="48348" checksum="B76E2BCEEC2D539C" modified="2008-04-29" version="1">MNFHALLADINAIVWGPVTLCLLVGTGLYLTLRLKLIQVFKLPMALGLLFKPANGKGDLSSFAALCTALSATIGTGNIVGVATAIKIGGPGALFWMWLAAFFGMATKYAECMLAVKYRTTDARGQIAGGPMYYIERGLGLSWLAKLFAIFGVGVAFFGIGTFAQVNAISDALTIAFHVPAWATSLVLTILVAAVTLGGVKRIANVAQKLVPTMALGYVLACLWVLITFSEQILPAFELVIHSAFTPISAAGGFLGATVAQALQIGIARGVFSNESGLGSAPIAAAAAKTNEPVEQGLVSMTGTFFDTIIICTMTGLVLIITGVWSGDTAGAAMTSAAFASGGSVLVGQYFVTVALVCFAFTTILGWHYYGERCWYYLMGERGLRAYQGVFLGLIALGSFIHLDMIWLLADTVNGLMAIPNLIAIIGLRHIIYLETLSYFTRFDKKDLEGTPSDVLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ3</accession>
    <name>B1KEQ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326399.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3809"/>
    <dbReference type="EnsemblBacteria" id="ACA88068">
        <property type="protein sequence ID" value="ACA88068"/>
        <property type="gene ID" value="Swoo_3809"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3809"/>
    <dbReference type="eggNOG" id="COG4278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124467_0_0_6"/>
    <dbReference type="OMA" id="CHFPEND"/>
    <dbReference type="OrthoDB" id="1487865at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="21892" checksum="684A85ABD45E5F1F" modified="2008-04-29" version="1">MNNSSLEAVLAYQNTDVTDRFIKLYGVKESEAVEIFEDVKRWLWMASETQKSVNKAVVIDSALVVLDEMWHNFMLFTRDYGQFCKEYFGGYIHHSPMTADEIAMAESELKGLSVAERKTALMEKKRWQYEFIYDQLGEQVFMRWYKQYPQLYTSKSLCEMALNTELKRSESLQLELARRSAELSDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV6</accession>
    <name>B1KEV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323454.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0812"/>
    <dbReference type="EnsemblBacteria" id="ACA85107">
        <property type="protein sequence ID" value="ACA85107"/>
        <property type="gene ID" value="Swoo_0812"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0812"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_7_3_6"/>
    <dbReference type="OMA" id="YTAQIPI"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="14026" checksum="66587CDA79E920C4" modified="2008-04-29" version="1">MTSRLIKQAVKTELFASKAPLEWAVVNNGTLYTAQIPINASGEVVAGGINAQSKQVMDNLMHTLEAAGVNSDAVLQVLIYVTDRSYLAEFNKVYSQYFTAPFPNRAAMVIAGLAREEMLVELVVYAAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW1</accession>
    <name>B1KEW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323459.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0817"/>
    <dbReference type="EnsemblBacteria" id="ACA85112">
        <property type="protein sequence ID" value="ACA85112"/>
        <property type="gene ID" value="Swoo_0817"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0817"/>
    <dbReference type="eggNOG" id="COG2055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097163_0_0_6"/>
    <dbReference type="OrthoDB" id="1724275at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022201">
        <property type="entry name" value="DUF3726"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12525">
        <property type="entry name" value="DUF3726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="27008" checksum="37F24FC7458F5AB5" modified="2008-04-29" version="1">MILVSHNELVGVTTKAFQGLRLPYGEADLIANMVADLEMVGLHGIKHFINALNYLGNKNNKPCHITFESSVEINIDLNDESILCHIPTILGYISDKLMDENRVKLNINNCCNRWLAFGELCKLSKNGISINACWDDFFEPIGIKYLLNSGDELPEIYIKRVEGENSELSNDNKRRLTIEFSNTHFKLPNSDEYQQHLSSSRLKRYQEESWTKGISVQVSDWEKLKQSSQAILVPCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEY3</accession>
    <name>B1KEY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85134">
        <property type="protein sequence ID" value="ACA85134"/>
        <property type="gene ID" value="Swoo_0839"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0839"/>
    <dbReference type="eggNOG" id="ENOG5032XV5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085419_0_0_6"/>
    <dbReference type="OMA" id="THKETSI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766515" evidence="1">
        <location>
            <begin position="24"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="29237" checksum="56B5DE79478D57E1" modified="2008-04-29" version="1" precursor="true">MRINNKSLIPHTMLLTLSLGLLACTNNVSSPKSSPQTGVTHKETSINLSKGQLFSLVMPKRREAGEQARQKYYKEVLPLGESFGLKREALLQIDDTLVGNFSPDGLIFYSWPSKAAENKLISHQDWPSMKQSRPQGWNEIKIYTQELERDLHLTFKPDKHYTLAVAWLNPTNPNDYLQYMDNIKESVNELGGRFIYKMNNPNFEAHASPLIAPGQLTFVEWDTPDGIAKFQQSSTFKQHSHLIKSGVNRFELYKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF19</accession>
    <name>B1KF19_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Transketolase</fullName>
            <ecNumber evidence="5 10">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0876</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="5 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323517.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0876"/>
    <dbReference type="EnsemblBacteria" id="ACA85170">
        <property type="protein sequence ID" value="ACA85170"/>
        <property type="gene ID" value="Swoo_0876"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0876"/>
    <dbReference type="eggNOG" id="COG0021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009227_0_0_6"/>
    <dbReference type="OMA" id="HHTEGIE"/>
    <dbReference type="OrthoDB" id="188169at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="663" mass="71468" checksum="33A252A7BCC2AAE5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFF7</accession>
    <name>B1KFF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88132">
        <property type="protein sequence ID" value="ACA88132"/>
        <property type="gene ID" value="Swoo_3874"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3874"/>
    <dbReference type="HOGENOM" id="CLU_2131838_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12753" checksum="FC0AF834CC53D2EF" modified="2008-04-29" version="1">MRANMDRVIGGDVINIEAPQDRQYLKFVVRVSSCDFDSINVRFYNSDGSAIKIDFSELRIGLVWNSETDVTTLGELEEVNKFEEGFVILGDFGTVYVYCDQCSPSLKTFITSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL9</accession>
    <name>B1KFL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326524.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3937"/>
    <dbReference type="EnsemblBacteria" id="ACA88194">
        <property type="protein sequence ID" value="ACA88194"/>
        <property type="gene ID" value="Swoo_3937"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3937"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022247_1_0_6"/>
    <dbReference type="OMA" id="NYALHFD"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033856">
        <property type="entry name" value="Trp_halogen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011396">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="502" mass="55768" checksum="CA901CB01D437E7E" modified="2008-04-29" version="1">MTPESIKKFVIVGGGTAGWIAAATLGNIFRHSEVEIELVESDDIGVIGVGEATIPPLLTILESLGIDLVDFIKHTQASFKLGIQFDDWHTIGEGYFHPFGTLGRSIDGHDFFQCWLKSKAEGDDTPLMAHSPEAVLAQQGRFFLPFEAQGTPLASTTFALHLDAVLAGKYLRKFAEKSGVKRTEGLVESVSRSDKGLIKSVTLQSGVEIAGDFFIDCSGFKGLLIEEALETGYEDWSEFLPCNRAVTVQTENMGDTTPYTIATARAAGWTWRIPLQHRTGNGYVFCDKYCSDEEAIETLLSSIEGQPLTEPRVIPFTTGVRHKAWNQNCLALGLAQGFLEPLESTAIHLVSKSLALFVRLFPTAECDTQLSDEFNRRVRQDYEEIRDFLVLHYCTTQRDDTPFWRWCQQMELPVKLKAKLDLFKVHGGLIPGTEELFQPTSWYAVFDGMGVEPVGYNPTLDAIDYHKLKQSLHSGKTAIQTSAATQPSHDEFLRTYCPAPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN1</accession>
    <name>B1KFN1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323544.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0903"/>
    <dbReference type="EnsemblBacteria" id="ACA85197">
        <property type="protein sequence ID" value="ACA85197"/>
        <property type="gene ID" value="Swoo_0903"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0903"/>
    <dbReference type="eggNOG" id="COG4807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087517_1_0_6"/>
    <dbReference type="OMA" id="KEDDMHA"/>
    <dbReference type="OrthoDB" id="1534707at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009921">
        <property type="entry name" value="DUF1456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07308">
        <property type="entry name" value="DUF1456"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1456" evidence="1">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1456" evidence="1">
        <location>
            <begin position="86"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="154" mass="17874" checksum="9428090A0C772E52" modified="2008-04-29" version="1">MINNDILRRIRFVFDYQNAKMIKIFAKVKHEVSQELLIDMLKKESEEGYQPCNDKTMCLFLDGLIIEKRGLREGAEIPEPVSQINNNLIFKKLRVALEMREDDIINTLALAEFNMSKSELGALFRKPGHKHFKECGDQVLRNFLAGLSLKYRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV0</accession>
    <name>B1KFV0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0973"/>
    <dbReference type="EnsemblBacteria" id="ACA85266">
        <property type="protein sequence ID" value="ACA85266"/>
        <property type="gene ID" value="Swoo_0973"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0973"/>
    <dbReference type="eggNOG" id="ENOG5033166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145974_0_0_6"/>
    <dbReference type="OMA" id="MMAWGIE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15634" checksum="C4E1CB610875AD97" modified="2008-04-29" version="1">MEYVQLTKNTILPDISKLGPFRCIVVVEKGVPEVRQKEVSAWLVESGCLYMMAWGIECGSWDTSVDIANLEKFDFNEIPEENLIITIWHNDEPLSEVFWYSKHCAFHSTVEIENTVLLNISAIDKSNQYLSEYINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGD1</accession>
    <name>B1KGD1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326597.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4012"/>
    <dbReference type="EnsemblBacteria" id="ACA88268">
        <property type="protein sequence ID" value="ACA88268"/>
        <property type="gene ID" value="Swoo_4012"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4012"/>
    <dbReference type="eggNOG" id="ENOG503453E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_495078_0_0_6"/>
    <dbReference type="OMA" id="KATIDIC"/>
    <dbReference type="OrthoDB" id="215800at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="559" mass="63865" checksum="336B1E1AAF33E6D2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG0</accession>
    <name>B1KGG0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85288">
        <property type="protein sequence ID" value="ACA85288"/>
        <property type="gene ID" value="Swoo_0995"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0995"/>
    <dbReference type="eggNOG" id="ENOG50333TE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137395_0_0_6"/>
    <dbReference type="OMA" id="YGAFGEH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="149" mass="17226" checksum="A0C7F9FC74E88E5F" modified="2008-04-29" version="1">MLMLGGILVLLIIAVSFYIYHQPHRKRKRAAKAAPTHISESAPEVKSTPFCSTKHPYHCVTIIQGEPACQAVKELNNTYYLSHEAPHIPLKECDIAQCNCHYQHKEDRRGTQENRRLEFGVTKELYGAFGEKNRRKLSRGRRKEDHEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL1</accession>
    <name>B1KGL1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323685.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1046"/>
    <dbReference type="EnsemblBacteria" id="ACA85339">
        <property type="protein sequence ID" value="ACA85339"/>
        <property type="gene ID" value="Swoo_1046"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1046"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_10_4_6"/>
    <dbReference type="OMA" id="HYARFEC"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="129" mass="15323" checksum="682022011C8493B6" modified="2008-04-29" version="1">MNMNQVTFPVNDMHKATEFYRLMGFIQIVDTPHYARFECSDGHASFSLSLQPEEQRNYGVIYFEHQNLDQLVAQLIEKGFHFDQMPTMESYLWREAVLHDPSGNKIKLYWAGENRLNPPWRVQKDKQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGW3</accession>
    <name>B1KGW3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325173.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2555"/>
    <dbReference type="EnsemblBacteria" id="ACA86832">
        <property type="protein sequence ID" value="ACA86832"/>
        <property type="gene ID" value="Swoo_2555"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2555"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_109_3_6"/>
    <dbReference type="OMA" id="LDEYQQM"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="248"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="388"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="634" mass="71912" checksum="2766BF7180063224" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE5</accession>
    <name>B1KHE5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_1160</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPPK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323799.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1160"/>
    <dbReference type="EnsemblBacteria" id="ACA85453">
        <property type="protein sequence ID" value="ACA85453"/>
        <property type="gene ID" value="Swoo_1160"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1160"/>
    <dbReference type="eggNOG" id="COG0801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097916_2_2_6"/>
    <dbReference type="OMA" id="TNAFVLW"/>
    <dbReference type="OrthoDB" id="1953248at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="13">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="168" mass="18889" checksum="7748EF0943D38740" modified="2008-04-29" version="1">MSARIFISLGSNIEPEHYIKAALSELSYHFSNLLCSSVFESEAVGFEGCNFLNMVVAADTELSISEVVAVFKKIEQENGRIPGAKKFSARSLDLDLLLYDDLVCQEPVELPRAEILTNAFVLWPLAEIAPQLIHPVTGQSYQSLWDEYDKRRQKLWTIPFTCPQMASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ1</accession>
    <name>B1KHJ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325216.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86876">
        <property type="protein sequence ID" value="ACA86876"/>
        <property type="gene ID" value="Swoo_2599"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2599"/>
    <dbReference type="eggNOG" id="ENOG5030T36">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1214130_0_0_6"/>
    <dbReference type="OMA" id="DTQWVFA"/>
    <dbReference type="OrthoDB" id="1653601at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764487" evidence="1">
        <location>
            <begin position="26"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="229" mass="25979" checksum="2E7F8FA6A5EFBE43" modified="2008-04-29" version="1" precursor="true">MPNLIRVTLPLMAALLSTVSLSAQAQLNRHIADPLNLKTSLGIGFDADVFKVGGRLGGESQKIELHTNMGGDKWTLSYLYAPVSSGNRLNISAKVNHGKTDTEIGRLSHYQYQFGVISEYVGWYETLVFTELAANYLSIDEHSSSNSFAANASFSVLKPWSDRWYNQLTTQASAAIDGRERFESEAWLSLGYRLSEQWSWEVRYRYEAHRIDEIEHEDTQWVFALQSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL0</accession>
    <name>B1KHL0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavocytochrome MsrQ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">msrQ</name>
        <name evidence="10" type="ordered locus">Swoo_2618</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="8">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MsrQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325235.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2618"/>
    <dbReference type="EnsemblBacteria" id="ACA86895">
        <property type="protein sequence ID" value="ACA86895"/>
        <property type="gene ID" value="Swoo_2618"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2618"/>
    <dbReference type="eggNOG" id="COG2717">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080662_0_1_6"/>
    <dbReference type="OMA" id="LHFFWMR"/>
    <dbReference type="OrthoDB" id="1508607at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01207">
        <property type="entry name" value="MsrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022837">
        <property type="entry name" value="MsrQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36964">
        <property type="entry name" value="PTHR36964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="9">
        <location>
            <begin position="48"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="24432" checksum="AFDD22CBCBF46670" modified="2008-04-29" version="1">MRLTMKHLFWLKLAIHLLAILPVAYLILLILTDKAGGDPVQYIIHYTGIGALNTLVILLCISPIARKFKQGVLIQTRRVIGLYVFAYANLHIFAFISLDLLFAWSLLFEEVVKRPYILVGAISYIILFLLSITSFKALRRKMGKRWQQLHNLVYLLAMLVPIHFYWSVKSEVIEPGIYIVLTSLLLLIRSPLPKQFSVFCLRLKNKLGSFTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL4</accession>
    <name>B1KHL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325239.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2622"/>
    <dbReference type="EnsemblBacteria" id="ACA86899">
        <property type="protein sequence ID" value="ACA86899"/>
        <property type="gene ID" value="Swoo_2622"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2622"/>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_50_6"/>
    <dbReference type="OMA" id="YLKFDRH"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="242" mass="27630" checksum="990D3CECF8D5993B" modified="2008-04-29" version="1">MIPLDRLYLSAEYQPLIDSKSLNVFGYEALSRFHDDHGNSTPPNIVFEQLHKEEQLLSVIEYKAKAFQIRHSNLAHPLFINLDPHAAEHNFDELLLLLTSREEITVELIENTCINDARLSSKLLSQLKAKQIKVALDDIGAPHSMISLDLLSQVNTLKFDIDWFNKTSQNELNLIKALIQFAKNSNKLTVLEGIETEEQLELARRLQIDLVQGFLFKEQFVKTPTSVKLIPQLSAEKEEIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR3</accession>
    <name>B1KHR3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GSH synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <shortName evidence="10">GSHase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gshB</name>
        <name evidence="13" type="ordered locus">Swoo_4135</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326720.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4135"/>
    <dbReference type="EnsemblBacteria" id="ACA88391">
        <property type="protein sequence ID" value="ACA88391"/>
        <property type="gene ID" value="Swoo_4135"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4135"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068239_0_0_6"/>
    <dbReference type="OMA" id="WMRKDPP"/>
    <dbReference type="OrthoDB" id="878336at2"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00162">
        <property type="entry name" value="GSH_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006284">
        <property type="entry name" value="Glut_synth_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004218">
        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004215">
        <property type="entry name" value="GSHS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
        <property type="entry name" value="PTHR21621:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02955">
        <property type="entry name" value="GSH-S_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02951">
        <property type="entry name" value="GSH-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01380">
        <property type="entry name" value="glut_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 10 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="125"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA88391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="316" mass="35306" checksum="4EA875CAE7A4C4DE" modified="2008-04-29" version="1">MIKLGIVMDPISEINIKKDSSFAMLLAAQSRGYELFYMEMKDLAMVNGKAMATMRSLSVQQDENNWFELGESVDTPLADLDVILMRKDPPFDTEFIYATYMLERAEEAGVLIVNKPQSLRDANEKLFTAWFSEFTPETIVTRDEKRIRQFYQEKKDIIIKPLDGMGGSSIFRVKEKDPNLGVIIETLTNHGQQYTMVQGFIPDITSGDKRILVVDGEPVPYSLARIPQKGETRGNLAAGGRGVAQPLSESDWKIARTIGPELKKRGLIFVGLDVIGDKLTEINVTSPTCIKEIQAAFDVDITGMLMDAIEARIKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR4</accession>
    <name>B1KHR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alkaline phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4136</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4136"/>
    <dbReference type="EnsemblBacteria" id="ACA88392">
        <property type="protein sequence ID" value="ACA88392"/>
        <property type="gene ID" value="Swoo_4136"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4136"/>
    <dbReference type="eggNOG" id="COG1785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008539_6_2_6"/>
    <dbReference type="OMA" id="NIYAYAN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767068" evidence="7">
        <location>
            <begin position="25"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="476" mass="51560" checksum="91178F9F81E81DA1" modified="2008-04-29" version="1" precursor="true">MTLTRSLFTGLALLSSALLGIAHANDDSPGLTMMGTTPSVPKNIVIMIGDGMGPAYTSAYRYYKNNPDTEEIEQTVFDRLLVGSASTYPAKISGYVTDSAAAATALATGIKSYNGAVSVDIHKRPITTIMEQAKKRGLATGIAVTSQINHATPAAFLTHNESRRNYDEIAKSLLNTDTDVMLGGGKRYFPAKLIQQFEAKGYQYLSDFSQLETASSPKVIGLFADVQLPWAINERGAHKLSKMTSKALELLSKNQDGFVLLVEGSLIDWAGHNNDIVTAMAEMDEFANAIEVVEQYARQHNDTLMLVTADHNTGGLSIGAEGEYIWKTDIINGVSTSPDVIATRALKYDDWQTKVSDALGFKLSQNEETQLSLARMQGVEVMTTAIKNLIDTRSFTGWTTGGHTGVDVQIFASGPASTLFSGFQDNTDIANKLMSLLPKEAKVVNQVKQSSTIDKRVEVNDIEVNEPVVDTPTLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR7</accession>
    <name>B1KHR7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326724.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4139"/>
    <dbReference type="EnsemblBacteria" id="ACA88395">
        <property type="protein sequence ID" value="ACA88395"/>
        <property type="gene ID" value="Swoo_4139"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4139"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124904_0_0_6"/>
    <dbReference type="OMA" id="RQIFTGH"/>
    <dbReference type="OrthoDB" id="1775689at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767359" evidence="1">
        <location>
            <begin position="21"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15903" checksum="8D1194379B290591" modified="2008-04-29" version="1" precursor="true">MRLLATWMLLFYLFCAHSIAAQVIVNDSAVDFPLPAKELRLIFSMQKTYWPDGNKIHVFILHPSSELHKEFCFQQLDMMPYMLQRRWDRLVFSGTGERPQILRSEAEMKQLILQTPGAIGYISNTASVTGVLYVYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHU4</accession>
    <name>B1KHU4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Ubiquinol-cytochrome c reductase iron-sulfur subunit</fullName>
            <ecNumber evidence="5 17">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Swoo_4166</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="17">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 18">The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="17">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="5 17"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326751.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4166"/>
    <dbReference type="EnsemblBacteria" id="ACA88422">
        <property type="protein sequence ID" value="ACA88422"/>
        <property type="gene ID" value="Swoo_4166"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4166"/>
    <dbReference type="eggNOG" id="COG0723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_0_2_6"/>
    <dbReference type="OMA" id="KRTWLIA"/>
    <dbReference type="OrthoDB" id="1632945at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019470">
        <property type="entry name" value="Ubiq_cytC_Rdtase_Fe-S_su_TAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10399">
        <property type="entry name" value="UCR_Fe-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="17" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="19">
        <location>
            <begin position="73"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACA88422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="196" mass="20937" checksum="91BB89588A15AD2C" modified="2008-04-29" version="1" precursor="true">MSNAPVDTGRRRFLTAATAVVGGAGAVAVAVPFIKSWNPSAKAKAAGAPVEVNISKVEPGQLIRVEWRGKPVWVVRRTEEILENLATLDDQLRDPASVEEQQPAYAQNAGRSINPEFFIAVGLCTHLGCSPTYLPDTFGEQVEGVPSGFFCPCHGSKFDMAGRVFQGVPAPLNLVVPPHQYIDDNNVIIGVDQGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHX4</accession>
    <name>B1KHX4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326781.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4196"/>
    <dbReference type="EnsemblBacteria" id="ACA88452">
        <property type="protein sequence ID" value="ACA88452"/>
        <property type="gene ID" value="Swoo_4196"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4196"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093491_1_0_6"/>
    <dbReference type="OMA" id="WVAVEHP"/>
    <dbReference type="OrthoDB" id="1258929at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026387">
        <property type="entry name" value="OMP_w_GlyGly"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04219">
        <property type="entry name" value="OMP_w_GlyGly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767076" evidence="1">
        <location>
            <begin position="22"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="249" mass="26711" checksum="F92602C994A432A9" modified="2008-04-29" version="1" precursor="true">MKKTLLACALLGSLAATSAQASTLVGFKVGGDYWQADTSGTFAESGQPQQDFNYSSSSQGSIWVAVEHPIPLVPNVKIRENRLDDNGSATVDGFEFGGTTFDGAVSTSTNLSNTDFVLYYELLDNDLVALDLGAAYKKMHGSLRVNHTETQGRVSAEKDLDSGIVMAYADAQVGVPGLGLYGFAEVMLGVDETSVYDYSVGLGWQFDGVALDTKVRLGYRDFSFDVNDFDGVSTNSQFKGYFAGVELVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI19</accession>
    <name>B1KI19_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1204"/>
    <dbReference type="EnsemblBacteria" id="ACA85497">
        <property type="protein sequence ID" value="ACA85497"/>
        <property type="gene ID" value="Swoo_1204"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1204"/>
    <dbReference type="eggNOG" id="ENOG50315K0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128770_0_0_6"/>
    <dbReference type="OMA" id="VWIAFTP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="18642" checksum="7500F0E990FE65D4" modified="2008-04-29" version="1">MERHTSKPVEEAVTETVSDTGNQELPKASAAELAKSKAKLPKRLLALCFFFAIASISGIVAKQGVLFCVLTLMMVVAILGRQRTAMYMLQGYTVIQLGLVSMLPVILYDPDNLVVGNPSIFRLGELEAKVPDYVIFAILILLSMLQVWIAFTPKVKAYFNSKINMNIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI80</accession>
    <name>B1KI80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c prime</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1266</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="7">Binds 1 heme group per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323904.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1266"/>
    <dbReference type="EnsemblBacteria" id="ACA85558">
        <property type="protein sequence ID" value="ACA85558"/>
        <property type="gene ID" value="Swoo_1266"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1266"/>
    <dbReference type="eggNOG" id="COG3909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106713_4_0_6"/>
    <dbReference type="OMA" id="HYRQSAF"/>
    <dbReference type="OrthoDB" id="2061303at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010980">
        <property type="entry name" value="Cyt_c/b562"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002321">
        <property type="entry name" value="Cyt_c_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012127">
        <property type="entry name" value="Cyt_c_prime"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01322">
        <property type="entry name" value="Cytochrom_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000027">
        <property type="entry name" value="Cytc_c_prime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47175">
        <property type="entry name" value="SSF47175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51009">
        <property type="entry name" value="CYTCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764516" evidence="8">
        <location>
            <begin position="25"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000027-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000027-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="153" mass="16493" checksum="CC7E0B2F102FBC53" modified="2008-04-29" version="1" precursor="true">MNKNAKMAILAVVTSTVLATSVQAGNFKKTDDAIEYRQSAFSLLAYNFGDMGAMLKGKKPFDAEVFAMRADNVAALSKLPLEGFTPGSDKGDTEALPKVWTEKADFDAKMLQLQKDSAALAIAAKADDKKALKQAFMATAKNCKGCHDSYKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC6</accession>
    <name>B1KIC6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cold shock-like protein CspD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2701</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012142231.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2701"/>
    <dbReference type="EnsemblBacteria" id="ACA86977">
        <property type="protein sequence ID" value="ACA86977"/>
        <property type="gene ID" value="Swoo_2701"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2701"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117621_0_3_6"/>
    <dbReference type="OMA" id="HYSTIKM"/>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012751">
        <property type="entry name" value="CspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02381">
        <property type="entry name" value="cspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="4">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="68" mass="7294" checksum="803C76946207294D" modified="2008-04-29" version="1">MANGTVKWFNNAKGFGFICPEAGGEDVFAHYSTIEMEGYRTLKAGQPVQFEVEAGPKGMHASAISPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIL4</accession>
    <name>B1KIL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Decaheme cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326837.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4254"/>
    <dbReference type="EnsemblBacteria" id="ACA88510">
        <property type="protein sequence ID" value="ACA88510"/>
        <property type="gene ID" value="Swoo_4254"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4254"/>
    <dbReference type="eggNOG" id="COG3303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011293_1_0_6"/>
    <dbReference type="OMA" id="ENAHYDW"/>
    <dbReference type="OrthoDB" id="864595at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020014">
        <property type="entry name" value="Decahaem_cyt-c_OmcA/MtrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03507">
        <property type="entry name" value="decahem_SO1788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767095" evidence="2">
        <location>
            <begin position="24"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="729" mass="78596" checksum="733A34C962CD51A9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP5</accession>
    <name>B1KIP5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326868.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88541">
        <property type="protein sequence ID" value="ACA88541"/>
        <property type="gene ID" value="Swoo_4286"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4286"/>
    <dbReference type="HOGENOM" id="CLU_377165_0_0_6"/>
    <dbReference type="OrthoDB" id="2105448at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767377" evidence="1">
        <location>
            <begin position="26"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="735" mass="80818" checksum="A6DCB05C9E4FC91F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIR2</accession>
    <name>B1KIR2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326885.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4304"/>
    <dbReference type="EnsemblBacteria" id="ACA88558">
        <property type="protein sequence ID" value="ACA88558"/>
        <property type="gene ID" value="Swoo_4304"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4304"/>
    <dbReference type="HOGENOM" id="CLU_2289763_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="101" mass="12107" checksum="EC95B06D826E1EA8" modified="2008-04-29" version="1">MTKQDKTEFKYEVDEYWFKFSNFMQLIFGGACIAYAKWQANEDSTSFRAFEFSKTEDPFMFWFCIIFIISTGCLSIYLGLIPFLHWCKNWLSNKRLNSDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU8</accession>
    <name>B1KIU8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323942.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1304"/>
    <dbReference type="EnsemblBacteria" id="ACA85596">
        <property type="protein sequence ID" value="ACA85596"/>
        <property type="gene ID" value="Swoo_1304"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1304"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_4_6"/>
    <dbReference type="OMA" id="YVLNGPA"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="340" mass="37145" checksum="B097FE69664A3828" modified="2008-04-29" version="1">MKVTINDVAKYAGVSIKTVSRVTNNEPSVKQATVDKVNEAIKALDYQPNLAARNLAGTKSYVIGFIYDNPNAYYVIDMQNGILSSCKDMGYELLIHPCNAKSDSICDELTTMVKHARLAGLVLTPPLSEDPKVLKALDEIDANYVRIIAGDKIKEDTGLAVLVNDKHGAVSITQHLIDLGHKKIAFLSGDQHHESTKERLTGFTQAMTSNKLDVDEKDIIAGQYSFESGVEGAKELLSRDKIDRPTAIVACNDEIAAGALFAARLEGVEIPNQLSIVGFEDSPFSRQTWPKLTTVHQPNQKIAQIATELLIAKRRSISAEQAKIFIPEPVIRDSSSEASN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIW4</accession>
    <name>TRMB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trmB</name>
        <name type="ordered locus">Swoo_1320</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323958.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIW4"/>
    <dbReference type="SMR" id="B1KIW4"/>
    <dbReference type="STRING" id="392500.Swoo_1320"/>
    <dbReference type="EnsemblBacteria" id="ACA85612">
        <property type="protein sequence ID" value="ACA85612"/>
        <property type="gene ID" value="Swoo_1320"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1320"/>
    <dbReference type="eggNOG" id="COG0220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050910_0_1_6"/>
    <dbReference type="OMA" id="PDPWHKS"/>
    <dbReference type="OrthoDB" id="1025521at2"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000149662" description="tRNA (guanine-N(7)-)-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="216"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <sequence length="238" mass="26818" checksum="D383F81CF0B2A123" modified="2008-04-29" version="1">MSDVTTAEFNEEGKYLRKVRSFVLREGRLTKGQATAMEEQWPLMGLDYSPEPLDLAEIFGREADTVLEIGFGMGASLVEMAKASPELNFIGIEVHKPGVGACLSVAAEAGVTNLRVFHHDAIEVLENSIVPSSLARVQLFFPDPWHKKRHHKRRIVQPEFAQTIRNSLKLGGVFHLATDWENYSEHMLEVMNAAPGYKNQSTTGDVVERPDHRPLTKFEARGHRLGHGVWDIMFERID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIX8</accession>
    <name>B1KIX8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twitching motility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323972.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1334"/>
    <dbReference type="EnsemblBacteria" id="ACA85626">
        <property type="protein sequence ID" value="ACA85626"/>
        <property type="gene ID" value="Swoo_1334"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1334"/>
    <dbReference type="eggNOG" id="COG5008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013446_4_0_6"/>
    <dbReference type="OMA" id="QGLCRTT"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="114"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="370" mass="40955" checksum="58EFC8E21F269E0B" modified="2008-04-29" version="1">MDVRPFLKIMVERKASDLFITAGFPPSAKIDGELRPLGEHSFSAAQSLEFVESLMTDVQKEEFHNTRECNFAFAAKELGRFRVSAFWQRESPGCVMRRIETNIPDADDLKLPPILKDLVMSKRGLIIMVGGTGTGKSTSLASLVGYRNANARGHILTIEDPVEFVHDHRKSIITQREVGIDTESFDAALKSSLRQAPDVILIGEIRTQETMEFALAFAETGHLCMATLHANNANQALDRIMNLVPESKHQQLLFDLSLNLRGIVAQQLVPKADGLGRRAAIEILINTPRVSSLIAKNELHSLKETMAKSNEQGMQTFDQALLNLYVEGEISYADALHHADSPNDLRLMIKLRSSETGGSGFMEGVTLDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ16</accession>
    <name>B1KJ16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325372.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2760"/>
    <dbReference type="EnsemblBacteria" id="ACA87036">
        <property type="protein sequence ID" value="ACA87036"/>
        <property type="gene ID" value="Swoo_2760"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2760"/>
    <dbReference type="eggNOG" id="COG0347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159089_1_1_6"/>
    <dbReference type="OMA" id="MHFKLII"/>
    <dbReference type="OrthoDB" id="1986500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="116" mass="12844" checksum="CA2785D39055114B" modified="2008-04-29" version="1">MRFKLIIAFIDDSTTNRILDAAREAGATGATVINHARGEGLEKKKTFMGLTLDVQRDVVLFLVEEHKSRVILETINRVGEFDTNPGQGIAIQIDVEDAVGVAHQVREISKDIEDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ53</accession>
    <name>B1KJ53_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2798</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325409.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2798"/>
    <dbReference type="EnsemblBacteria" id="ACA87073">
        <property type="protein sequence ID" value="ACA87073"/>
        <property type="gene ID" value="Swoo_2798"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2798"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039400_0_0_6"/>
    <dbReference type="OMA" id="TRGIAHS"/>
    <dbReference type="OrthoDB" id="849270at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="250"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="322"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="82"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="536" mass="59735" checksum="8C3E8A38BF5FEFA3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ57</accession>
    <name>B1KJ57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325413.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2802"/>
    <dbReference type="EnsemblBacteria" id="ACA87077">
        <property type="protein sequence ID" value="ACA87077"/>
        <property type="gene ID" value="Swoo_2802"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2802"/>
    <dbReference type="eggNOG" id="COG3638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="IGTLWQD"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="24586" checksum="16544055742EB30F" modified="2008-04-29" version="1">MVNIDNLTLKYADKLAIRQLSLSIASGEKVAIIGPSGSGKSTLLSHLYLLLKESAAFCSQKQGLVDGLSTYHNVYMGALSRHHWSYNLINLIAPFSTPLAEVEALCHQLSLDVPMSKVLSKLSGGQRQRVALARALYQQQATFIGDEPFSALDPLMAEQLLTMVLAGHSTCIIALHDKSEALRHFDRILGLRDGKLCLDITQDALTPEVIDNFYSPEILPLVSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI5</accession>
    <name>B1KJI5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1366</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324004.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1366"/>
    <dbReference type="EnsemblBacteria" id="ACA85658">
        <property type="protein sequence ID" value="ACA85658"/>
        <property type="gene ID" value="Swoo_1366"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1366"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="TSYNRMS"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="853"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="879"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="905"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="954"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="980"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1035" mass="112387" checksum="6ACB07C572859698" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJJ1</accession>
    <name>B1KJJ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324010.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1372"/>
    <dbReference type="EnsemblBacteria" id="ACA85664">
        <property type="protein sequence ID" value="ACA85664"/>
        <property type="gene ID" value="Swoo_1372"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1372"/>
    <dbReference type="eggNOG" id="ENOG5031NB7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167650_1_0_6"/>
    <dbReference type="OMA" id="CYLAFNE"/>
    <dbReference type="OrthoDB" id="1956183at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021432">
        <property type="entry name" value="DUF3081"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11280">
        <property type="entry name" value="DUF3081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="82" mass="9402" checksum="CDB15EBB43A6B5FC" modified="2008-04-29" version="1">MKNNLDVKRSLLIFNQIISHGERNNGRSVFNGMSAWYDFDGYTCYLAFNEVTLTLLFHGKYLIDSPSAESLAAFEKKLSQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJN4</accession>
    <name>B1KJN4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324053.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1415"/>
    <dbReference type="EnsemblBacteria" id="ACA85707">
        <property type="protein sequence ID" value="ACA85707"/>
        <property type="gene ID" value="Swoo_1415"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1415"/>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101159_6_0_6"/>
    <dbReference type="OMA" id="DIYCAQC"/>
    <dbReference type="OrthoDB" id="1939800at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008168">
        <property type="entry name" value="Cyt_C_IC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00605">
        <property type="entry name" value="CYTCHROMECIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767406" evidence="5">
        <location>
            <begin position="22"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="21"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="123" mass="13701" checksum="23B5CEC61A52134C" modified="2008-04-29" version="1" precursor="true">MRTFHCILLLLSLALSGQLAAESTKGELLYQAYCTQCHGKEGDGWGVNAATMDVLPKDHTDTKEMISRTDEDIFIAIKKGGKAVSKSNLMPNWDANMTDEEINELVVYVRTLCCQKEELSDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ6</accession>
    <name>B1KJQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kojibiose phosphorylase</fullName>
            <ecNumber evidence="7">2.4.1.230</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1437</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 65 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.230" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324075.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1437"/>
    <dbReference type="CAZy" id="GH65">
        <property type="family name" value="Glycoside Hydrolase Family 65"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85729">
        <property type="protein sequence ID" value="ACA85729"/>
        <property type="gene ID" value="Swoo_1437"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1437"/>
    <dbReference type="eggNOG" id="COG1554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006285_2_2_6"/>
    <dbReference type="OMA" id="EAYCIPF"/>
    <dbReference type="OrthoDB" id="179460at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033831">
        <property type="term" value="F:kojibiose phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005194">
        <property type="entry name" value="Glyco_hydro_65_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005195">
        <property type="entry name" value="Glyco_hydro_65_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017045">
        <property type="entry name" value="Malt_Pase/Glycosyl_Hdrlase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03633">
        <property type="entry name" value="Glyco_hydro_65C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
        <property type="entry name" value="Glyco_hydro_65m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03636">
        <property type="entry name" value="Glyco_hydro_65N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036289">
        <property type="entry name" value="Glycosyl_hydrolase_malt_phosph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_hydro_65N" evidence="6">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65m" evidence="4">
        <location>
            <begin position="336"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65C" evidence="5">
        <location>
            <begin position="720"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="370"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="612"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR036289-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR036289-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="788" mass="89455" checksum="6D0387EBD63F94D2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJS8</accession>
    <name>B1KJS8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325451.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87115">
        <property type="protein sequence ID" value="ACA87115"/>
        <property type="gene ID" value="Swoo_2840"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2840"/>
    <dbReference type="HOGENOM" id="CLU_2525703_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="84" mass="9572" checksum="BC5785B78B8FA7FB" modified="2008-04-29" version="1">MSVRTKSNKKIIHLSLLPFFRHFIVFITDKASFVAIAMNFNLASLLLITVNMYHETFNTVDFVVSGLLLLSNLSVSFYMINSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJV8</accession>
    <name>B1KJV8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proton-translocating NADH-quinone oxidoreductase, chain L</fullName>
            <ecNumber evidence="9">1.6.5.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.5.11" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325481.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2870"/>
    <dbReference type="EnsemblBacteria" id="ACA87145">
        <property type="protein sequence ID" value="ACA87145"/>
        <property type="gene ID" value="Swoo_2870"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2870"/>
    <dbReference type="eggNOG" id="COG1009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_6_2_6"/>
    <dbReference type="OMA" id="GFWYREV"/>
    <dbReference type="OrthoDB" id="1274678at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="502"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="601"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="8">
        <location>
            <begin position="66"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="7">
        <location>
            <begin position="132"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="622" mass="68448" checksum="AD991D01E3002310" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW8</accession>
    <name>B1KJW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Formate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FNT transporter (TC 2.A.44) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325491.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2880"/>
    <dbReference type="EnsemblBacteria" id="ACA87155">
        <property type="protein sequence ID" value="ACA87155"/>
        <property type="gene ID" value="Swoo_2880"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2880"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036896_4_0_6"/>
    <dbReference type="OMA" id="ISWANKQ"/>
    <dbReference type="OrthoDB" id="1834167at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015499">
        <property type="term" value="F:formate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024002">
        <property type="entry name" value="For/NO2_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023999">
        <property type="entry name" value="Formate_transptr_FocA_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="PTHR30520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00790">
        <property type="entry name" value="fnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04060">
        <property type="entry name" value="formate_focA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01005">
        <property type="entry name" value="FORMATE_NITRITE_TP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="341"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="494" mass="53889" checksum="9BF01B5FEE252CA9" modified="2008-04-29" version="1">MTSNQKVSGLTLARVMQNSEEVTQTAPVSLYQQAEHYGKSKVVKSAWQSFGLAAFAGAFIALAFVFYITVTTGNDGSAWGLMRLAGGLAFSLGLMLVVICGGELFTSTVLSSVAWAQKLVTGRELIKCWGRVYVGNLLGALIMLFLIMSARMYDLDGGQWGLNALQIAQHKLHHTWLQAFVLGILCNMLVCLGVWMTFSSKDALTKAVLLMLPVAMFVSSGFEHSIANLFMVPLGIAISQFAQPEFFISLGIDAAQFTDLTMSHFIVNNLIPVTLGNIVGGGVFVGLGYWLIEKSAQKIKTPLALCVPQLETSAQIHSISTSGVSNKMPKTIQKLCVQDLMDTSPLTISSEQSVYAGLALLTDNDCRSAPVLDENQHLLGFISQQDLLRSLWSEEFARGVSYKVADLMQKEVMTLSPQDSVAELIELMVVDRNKLFPVNESGILTGNTFKSYEERLRCASANKPSVFPVVEKGLLRGVITREAIARKVCDIYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK38</accession>
    <name>B1KK38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pilus (MSHA type) biogenesis protein MshL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4417</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326995.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4417"/>
    <dbReference type="EnsemblBacteria" id="ACA88669">
        <property type="protein sequence ID" value="ACA88669"/>
        <property type="gene ID" value="Swoo_4417"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4417"/>
    <dbReference type="eggNOG" id="COG1450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006756_3_1_6"/>
    <dbReference type="OMA" id="MQRQVIL"/>
    <dbReference type="OrthoDB" id="870677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013358">
        <property type="entry name" value="Pilus_biogenesis_MshL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011514">
        <property type="entry name" value="Secretin_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07655">
        <property type="entry name" value="Secretin_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02519">
        <property type="entry name" value="pilus_MshL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="STN" evidence="6">
        <location>
            <begin position="100"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="172"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="562" mass="60749" checksum="AC0AAE3522A84242" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK56</accession>
    <name>B1KK56_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327013.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4435"/>
    <dbReference type="EnsemblBacteria" id="ACA88687">
        <property type="protein sequence ID" value="ACA88687"/>
        <property type="gene ID" value="Swoo_4435"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4435"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_11_3_6"/>
    <dbReference type="OMA" id="ILFATWC"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767139" evidence="1">
        <location>
            <begin position="22"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="38"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="19076" checksum="D8D6EF175B81630B" modified="2008-04-29" version="1" precursor="true">MKWISALNILLITLLMVGCTSSPTKLTQHNSSEYQTFVKVGEQVPVTQFIDTQGEKIDLTQSHNAKLLILFATWCSDSQRAMKALKSSDLNLDPNIDIIGIGREESNETLDKFADEYELNFPLIADNDRSIYAKFANAGIPRFILLDKENQIVKTIIAEDDNPLTQLQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKA4</accession>
    <name>B1KKA4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid/peptide transporter</fullName>
            <ecNumber evidence="6">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4484</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327061.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4484"/>
    <dbReference type="EnsemblBacteria" id="ACA88735">
        <property type="protein sequence ID" value="ACA88735"/>
        <property type="gene ID" value="Swoo_4484"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4484"/>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_0_2_6"/>
    <dbReference type="OMA" id="SFYGMRV"/>
    <dbReference type="OrthoDB" id="470322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="516" mass="56746" checksum="0443CD0D8EC4C16A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKE9</accession>
    <name>B1KKE9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1501"/>
    <dbReference type="EnsemblBacteria" id="ACA85789">
        <property type="protein sequence ID" value="ACA85789"/>
        <property type="gene ID" value="Swoo_1501"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1501"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127635_0_0_6"/>
    <dbReference type="OMA" id="FEHHEVM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21199" checksum="847202B69E6722BA" modified="2008-04-29" version="1">MTHYQRAPELHVSEWLNTPEPITLAQLKGEVVVLHAFQMLCPTCVSHGLPQAQALHKLFADEKVNILGLHTVFEHHQVMDKAALKVFISEYRLSFPIGIDTPSTQGVIPKTMQEYMLRGTPSIIVIDKQGQIRLSHFGHIPDLALGKIVGQLVAEPFETDKHTSPSKDTDIFKPQEERAEKGCDQTGCSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI4</accession>
    <name>B1KKI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324170.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85824">
        <property type="protein sequence ID" value="ACA85824"/>
        <property type="gene ID" value="Swoo_1536"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1536"/>
    <dbReference type="eggNOG" id="COG3530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176025_0_0_6"/>
    <dbReference type="OMA" id="MPFGKYE"/>
    <dbReference type="OrthoDB" id="1886238at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024530">
        <property type="entry name" value="QSregVF_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40613">
        <property type="entry name" value="PTHR40613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12843">
        <property type="entry name" value="QSregVF_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="74" mass="8484" checksum="01B165F8E07BCEAF" modified="2008-04-29" version="1">MNEQILLEAINQKMPFGKYAGRKLLELPEPYLVWFHSKGFPEGKLGEQLALMYEIKLNGLEGMLQPLLAKVPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKK0</accession>
    <name>B1KKK0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325553.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2944"/>
    <dbReference type="EnsemblBacteria" id="ACA87217">
        <property type="protein sequence ID" value="ACA87217"/>
        <property type="gene ID" value="Swoo_2944"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2944"/>
    <dbReference type="eggNOG" id="ENOG502Z9AD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_677691_0_0_6"/>
    <dbReference type="OMA" id="AINSWVG"/>
    <dbReference type="OrthoDB" id="1533711at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767442" evidence="1">
        <location>
            <begin position="18"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="46768" checksum="753D5258B4038200" modified="2008-04-29" version="1" precursor="true">MKYWPWMLMLVSSNLMAAEHQVSGVVDIRVSHTDSITSYVDGGLGKFRFNPNGQLSLVQAGLSYHLDWENPFSAHVVANAYWDGVRDNIGFTEAYFKYKGLPWDNGLRLSGRFGLLYPSISLENIATAWSSPYTLTYSGINSWIGEEVRHVGGQLSIEQLGKFSGSPHDFKLTAEMFQSNDTTGAMLSWHGWTNSSRQTLLQEKLPLSELPSLNAGSLTEQARASDPFLELDNNIGYHLKTQWRMQGQGRVELGYYDNDGDTRVVKEGQYTWLTRFTHLGAKWRLPYRIELITQYLKGDTLMRAPSGINIVDNDYDSGFILLSRKWQKHRLSLRFEEFSVTDNDLTPDDDNSEHGNAATLSYGYQWHKGWFLQAEYNRIDSTRPARTAQGYDKRLIEQQWQLASRYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN1</accession>
    <name>B1KKN1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325584.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87248">
        <property type="protein sequence ID" value="ACA87248"/>
        <property type="gene ID" value="Swoo_2977"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2977"/>
    <dbReference type="eggNOG" id="ENOG5031IV6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2467287_0_0_6"/>
    <dbReference type="OMA" id="LFAIWML"/>
    <dbReference type="OrthoDB" id="2169248at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="9889" checksum="A043BEB95D89EBF1" modified="2008-04-29" version="1">MIATTPASGSSLNNLLLYHFLLVTAIALLILPFVTDNKIFELMLLLTMQIALTCISTLIGLSMKHRLNRNAVTFLFAIWMLVWCVHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN5</accession>
    <name>B1KKN5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Colicin V production protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2981</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325588.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2981"/>
    <dbReference type="EnsemblBacteria" id="ACA87252">
        <property type="protein sequence ID" value="ACA87252"/>
        <property type="gene ID" value="Swoo_2981"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2981"/>
    <dbReference type="eggNOG" id="COG1286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092720_2_1_6"/>
    <dbReference type="OMA" id="FTWVDWA"/>
    <dbReference type="OrthoDB" id="2032521at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="17987" checksum="41EC5FCD4F1064BF" modified="2008-04-29" version="1">MVWIDYAIFAVIGVSTLISLLRGFAKEAMSLVVWFAAFFVASQFYQDLSVYLTQMQDEMLRNGVAIAILFIATLILGALVNYLIGQLVEKTGLSGTDRVLGLCFGALRGALIVSALLFFMDAFTGAPNTDWWQSSKLVPEFGVVIQWFFDYLENTSSFVPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKR6</accession>
    <name>B1KKR6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved hypothetical lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325619.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3012"/>
    <dbReference type="EnsemblBacteria" id="ACA87283">
        <property type="protein sequence ID" value="ACA87283"/>
        <property type="gene ID" value="Swoo_3012"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3012"/>
    <dbReference type="eggNOG" id="ENOG502ZC5D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058624_0_0_6"/>
    <dbReference type="OMA" id="CENDADQ"/>
    <dbReference type="OrthoDB" id="1368901at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043724">
        <property type="entry name" value="DUF5666"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18914">
        <property type="entry name" value="DUF5666"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767162" evidence="1">
        <location>
            <begin position="23"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5666" evidence="2">
        <location>
            <begin position="48"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5666" evidence="2">
        <location>
            <begin position="112"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5666" evidence="2">
        <location>
            <begin position="173"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5666" evidence="2">
        <location>
            <begin position="242"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5666" evidence="2">
        <location>
            <begin position="327"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="437" mass="47128" checksum="00D3355C937AB3A7" modified="2008-04-29" version="1" precursor="true">MKSANAKNLLLASILATFVVGCGGGSSDSGSTTPEIPVAPTTPAKIFGSVEAVSTTNQTITVNGYTLQTAGTPINYEDNILELADLTPGVQVEVETLKGKAIDIELNPAIAGVVSEVQGNKLVVNGTTFTFSALNSDIQVGSWVMISALQQNDGTWSVSSVNQAPVLTHAEIEGRISLLDTTASKFNIGSMQVEYSNATIEYGDILKNGQWVEVDGNFENSHFVAAKIDVENDTDYDGVEIEGTITWVNSELSYFEIDNRTKIQVTANTKFEDGVKTDLKSGNQVDVDMANSSSGLVATNIDFENQQPEIPVTQAREFSNQGFATLNSGIVTINGTEFVIDAATHFDDGLTEAMLNNIWIEVEGIEVKATALTPAHWLIKEIERETKETEISLEGPVSNNSLWNYTSSDNSLAQFDGKWVEVECMLNGDDLLNCRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKS4</accession>
    <name>B1KKS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphohistidine phosphatase, SixA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3020"/>
    <dbReference type="EnsemblBacteria" id="ACA87291">
        <property type="protein sequence ID" value="ACA87291"/>
        <property type="gene ID" value="Swoo_3020"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3020"/>
    <dbReference type="eggNOG" id="COG2062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084603_1_1_6"/>
    <dbReference type="OMA" id="MQVLIMR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101006">
        <property type="term" value="F:protein histidine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004449">
        <property type="entry name" value="SixA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00249">
        <property type="entry name" value="sixA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="19191" checksum="61C2FCDDAA9E89CE" modified="2008-04-29" version="1">MCNIKIIIMSSESGMQLFLMRHGEASYLAHSDRERTLTDTGRYHTCEMSNWLAKSVTEFDLVLVSPYLRAQQSWQEVSKHFPEPRKWLVLDDLTPSSDPSTAADLTLAYAEQYKADNVLVIAHMPLLGYMVSELVRGVEPPLFATSGLALIDKHGEQCSLIWQHTPHSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKT3</accession>
    <name>B1KKT3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325636.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3029"/>
    <dbReference type="EnsemblBacteria" id="ACA87300">
        <property type="protein sequence ID" value="ACA87300"/>
        <property type="gene ID" value="Swoo_3029"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3029"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054927_1_0_6"/>
    <dbReference type="OMA" id="WNVTARY"/>
    <dbReference type="OrthoDB" id="848990at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="53"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="309" mass="34837" checksum="9A3230FD68D9659F" modified="2008-04-29" version="1">MADTRLPLFSDGVNLTQKELLACQTIARALPEKRSKARANLAGHRASLIKGRGMEFAEVRHYQPGDDVRTIDWRVTARTGKVHTKLFVEERERPVLILLDLSHSLYFGSSLLLQSVQAAHLATTLGWSAIQHGDRLGALIATEAEHLELKPRSRQQGILQLISAIQSLHERQLNQLSEYQSEPEHLFRACQRLRRIAKPGSLIWIISDGANLTENCLAPLSDLKRHCDMGAFLITDPLRQGTLALPKQFQLPVKEGNREMVLNRAGYDAWLQKQLSSQAHFTQMMQKLNVRTRFIDAGMSLNDQIGSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKX9</accession>
    <name>B1KKX9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">murD</name>
        <name evidence="17" type="ordered locus">Swoo_4535</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327111.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4535"/>
    <dbReference type="EnsemblBacteria" id="ACA88785">
        <property type="protein sequence ID" value="ACA88785"/>
        <property type="gene ID" value="Swoo_4535"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4535"/>
    <dbReference type="eggNOG" id="COG0771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032540_1_0_6"/>
    <dbReference type="OMA" id="CNFENYL"/>
    <dbReference type="OrthoDB" id="1093223at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="16">
        <location>
            <begin position="114"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="15">
        <location>
            <begin position="301"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="116"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA88785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="442" mass="47455" checksum="5FE155AA1E2D205D" modified="2008-04-29" version="1">MENIKSHVVLGLGATGLSVVHYLHEQGITPLVMDSRHQPPGMDELKRLYPEVELLTGGFDCRYLVQASQIIISPGIAVDTPEIRAAIDMGIEVIGDVELFARAVKDREPCVIGITGSNGKSTVTTLVGEMARVAGLNYAVGGNIGVPALDLLREPRDLYILELSSFQLETTHSLNCIVATCLNISEDHMDRYTDLEAYRQAKLSLYCQSKRALFNREDELTEPKDPMNQNSFGLSAPFNDEWGVRDGKVVHGTTEIMNLLDVALVGSHNHANLLAAMALAYHAGVDKESMIQVATTFTGLAHRCELVAVHNGVSYVNDSKATNVGATVAALEGFSDHLGGIILIAGGDGKGADFQPLQQAIHGLSQLITLGKDGDKIAEFSEKAIRVSDMSEAVKTANELAEAGDIVLMSPACASLDMYKNFMARGEDFRAEVNALAGSSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL29</accession>
    <name>B1KL29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322719.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0069"/>
    <dbReference type="EnsemblBacteria" id="ACA84370">
        <property type="protein sequence ID" value="ACA84370"/>
        <property type="gene ID" value="Swoo_0069"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0069"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_10_4_6"/>
    <dbReference type="OMA" id="RNARNKY"/>
    <dbReference type="OrthoDB" id="1968136at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043968">
        <property type="entry name" value="SGNH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19040">
        <property type="entry name" value="SGNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="5"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH" evidence="3">
        <location>
            <begin position="407"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="652" mass="73381" checksum="8507C13CCAF282E8" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD5</accession>
    <name>B1KLD5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324206.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1574"/>
    <dbReference type="EnsemblBacteria" id="ACA85860">
        <property type="protein sequence ID" value="ACA85860"/>
        <property type="gene ID" value="Swoo_1574"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1574"/>
    <dbReference type="eggNOG" id="ENOG5031F7Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1658980_0_0_6"/>
    <dbReference type="OMA" id="KWIFTHQ"/>
    <dbReference type="OrthoDB" id="1464694at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021334">
        <property type="entry name" value="DUF2947"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11163">
        <property type="entry name" value="DUF2947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="159" mass="19089" checksum="592174EFB28F40C5" modified="2008-04-29" version="1">MSHNYIPLEQYKRKWIFNHKDLPVTDEDKAFIKPLDQKGSMEVWNKWISNRSSNAEQFGKGDWPAKGNAWLETDHWQSAWDSEDPALPEMFANYIEWKEDEVVYFCYEKYQVIETRWDVFVRNWKCFLFFDDGPLLISPKQKQAVFIHQNGQYQLGNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLY9</accession>
    <name>B1KLY9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327194.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4619"/>
    <dbReference type="EnsemblBacteria" id="ACA88869">
        <property type="protein sequence ID" value="ACA88869"/>
        <property type="gene ID" value="Swoo_4619"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4619"/>
    <dbReference type="eggNOG" id="ENOG5032Y9Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183081_0_0_6"/>
    <dbReference type="OMA" id="PLHIWCI"/>
    <dbReference type="OrthoDB" id="1687355at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="75" mass="8030" checksum="CCEB44329F9FD1C6" modified="2008-04-29" version="1">MSQQGSAGNVIAAIASFFFVGLGQLVQGRILAAIIFCLTTYAAYGIATFTFGLFLIIALPLHLWCIIDAARYKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM91</accession>
    <name>B1KM91_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Cell division protein FtsX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0203</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter FtsEX involved in cellular division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Forms a membrane-associated complex with FtsE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322853.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0203"/>
    <dbReference type="EnsemblBacteria" id="ACA84504">
        <property type="protein sequence ID" value="ACA84504"/>
        <property type="gene ID" value="Swoo_0203"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0203"/>
    <dbReference type="eggNOG" id="COG2177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073546_0_0_6"/>
    <dbReference type="OMA" id="ETGIMRL"/>
    <dbReference type="OrthoDB" id="1653234at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004513">
        <property type="entry name" value="ABC_transpt_FtsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040690">
        <property type="entry name" value="FtsX_ECD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47755">
        <property type="entry name" value="PTHR47755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18075">
        <property type="entry name" value="FtsX_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003097">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX_ECD" evidence="11">
        <location>
            <begin position="79"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR003097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA84504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="321" mass="35657" checksum="051B52DFDD498451" modified="2008-04-29" version="1">MSNKPQLVRSKLPISGRIVMFFIRHIQHAMGSMGELWRNPVSSLMTMAVLGVSLSLPAALQVLVKNAEAITQSWNSAAEISLFIDDARSDKTIQSLISRVKVYSEVSEVNYINRDQALEEFQSLSGFGEAISYLDTNPLPAVVTVTPTLKYSSPTGARELLKKLEQEPEVSFGRLDIEWLERLQAVVRLLERTVLAIAALLVLAVVLVIGNTIRLAIMNRRTEIEVMKLVGATEAFIQRPFLYTGIWFGIIGGVLAWIIINLLVWYLDSALAELLGLYGSQLEMQTLTLVELGQLVCLASFLGWLGSYLSVRQHLRAIEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMM2</accession>
    <name>B1KMM2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Neutral metalloproteinase</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_3129</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Extracellular zinc metalloprotease.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase M4 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325736.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3129"/>
    <dbReference type="MEROPS" id="M04.016"/>
    <dbReference type="EnsemblBacteria" id="ACA87400">
        <property type="protein sequence ID" value="ACA87400"/>
        <property type="gene ID" value="Swoo_3129"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3129"/>
    <dbReference type="eggNOG" id="COG3227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008590_4_2_6"/>
    <dbReference type="OMA" id="HMKDYES"/>
    <dbReference type="OrthoDB" id="1465483at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022987660" description="Neutral metalloproteinase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="11">
        <location>
            <begin position="50"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4" evidence="9">
        <location>
            <begin position="209"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4_C" evidence="10">
        <location>
            <begin position="350"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="499" mass="54383" checksum="E44727318BEDA1D9" modified="2008-04-29" version="1" precursor="true">MKIPRLVPTLVAVCVTSSFHLQAAEFKFNKNQSINHAAGVSQLNHFEKSLSVKTAKGTQKSKQKQMFNGVPVYGHHLVVETDGESNIASGRLAQIDDEFSVQAGITRGQAIASLNKLYQGSAASGQKEVELVVLMQDKAPRLAYRVSYLSDKGDTISRPAGLVDANSGEVIRHWNELMTAKNGKGKPGGGTGGGTPVPYDASGPGGNAKVGRYYYGSDFGPLAVQESGGTCSMVNDNVKTINMKSKTRGGNTFTFTCPENTYKTTNDAYSPLNDAHYFGNVIFNMYQDWYQTAPLTFQLEMRVHYGRRYENAFWDGRAMSFGDGDSYFYPLVSLDVSAHEVSHGFTEQNSGLEYSGQSGGINESFSDMAGEAAEFYMRGSNDWKVGYDIVKGSGALRYMDDPTQDGNSIGDASYYTDGMDVHYSSGVFNRAFYLLSNKTGWDTHKSFDVFVLANQLYWSATSDFKDAACGAENAARDLGYPVADVTDAFAYVSTSCISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMN4</accession>
    <name>B1KMN4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NIPSNAP family containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325748.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3141"/>
    <dbReference type="EnsemblBacteria" id="ACA87412">
        <property type="protein sequence ID" value="ACA87412"/>
        <property type="gene ID" value="Swoo_3141"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3141"/>
    <dbReference type="eggNOG" id="COG5470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149116_1_0_6"/>
    <dbReference type="OMA" id="CFIRYQI"/>
    <dbReference type="OrthoDB" id="1925073at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="1">
        <location>
            <begin position="20"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="13271" checksum="20B2C896B54A7D81" modified="2008-04-29" version="1">MTSKNNLEQMPMKVTCHVKYIIDPDMLSEFEHYAKLWIPLVEKFGGQHHGYFLPSEGANDVAIALFSFPSLADYEVYRHESAQDVDCLSAFYYAKKHKFILRYERSFMRPVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ3</accession>
    <name>B1KMQ3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltranfer_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325767.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3160"/>
    <dbReference type="EnsemblBacteria" id="ACA87431">
        <property type="protein sequence ID" value="ACA87431"/>
        <property type="gene ID" value="Swoo_3160"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3160"/>
    <dbReference type="eggNOG" id="ENOG502Z7Q4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057688_0_0_6"/>
    <dbReference type="OMA" id="AIAPCCY"/>
    <dbReference type="OrthoDB" id="1557981at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="129"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="406" mass="46573" checksum="A77DB83D41155001" modified="2008-04-29" version="1">MSHSALLSQLDSLLLQSRQLWQVKAFDCDKQPWEENFPNLAALVWSLDDDILDELDRVQAELLNCLLPALNKDLVLLSESWSLELLNIKAPLCAGSRVREMEFQDIAHFSAGIKGRKWAQITAFTQELPADKCEVLEWCAGKGHLGRLISKSQGREVVSLEWQQALCDAGEKFAQQWQLPQKFVCADAFDNQQSELKVEQQAVALHACGDLHVRLLYLAAKAGTRHIAISPCCYHLIQAKEYQAMSKVGLQSELRLSRHDLQLPLQQSTIAKGKQQELRHREIAWRLGFDSLQREVRGGSCYLPIPSLKQSQLNGEFSTFCYWAAEQKSVDLPENLNFKRFLELGVERQRLTRRIDLVAHMFRGVFEHWLLLDRVCYLEEQGYEVTLEQFCNNEITPRNLLIKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMS4</accession>
    <name>B1KMS4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3181</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325788.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3181"/>
    <dbReference type="EnsemblBacteria" id="ACA87452">
        <property type="protein sequence ID" value="ACA87452"/>
        <property type="gene ID" value="Swoo_3181"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3181"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_784895_0_0_6"/>
    <dbReference type="OMA" id="NQACHAM"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="3">
        <location>
            <begin position="129"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="2">
        <location>
            <begin position="262"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="349" mass="37558" checksum="23927D651A6B525A" modified="2008-04-29" version="1">MGVKFAKNGLTLLSSAYVLPNEVVSNQELLEALGQLCGPLAKRKAKSIAKRLGVESRHLVRDLTSAKSQPSPNSIALGVDVLNQALVQAGLDVNELEYLLSHTCTPHTQVPPNAAWLADELRFQGPYLELRQACTGFANALQIASTFCTTDEAPVAIVGTETGSVYFEIAKAFLTTEQLVNYVQMGDGAGAVILGPAKKGEGQLTDIYFGQIGEGKAPGFYLDSGSMDVGKGEMTRFHHNTEAVRANGSQLFELGLQAVLSRGYQLDDFRYILPHQANGYIDLMLAEALGIEPERIINDAKGLGNLGSAAIWVSFAKLVNSGKLRRGDKVLILGAEATKYLYGGFVYHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN36</accession>
    <name>B1KN36_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4743</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327310.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4743"/>
    <dbReference type="EnsemblBacteria" id="ACA88993">
        <property type="protein sequence ID" value="ACA88993"/>
        <property type="gene ID" value="Swoo_4743"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4743"/>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_946273_0_0_6"/>
    <dbReference type="OMA" id="LLENLWP"/>
    <dbReference type="OrthoDB" id="1921545at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="294" mass="33046" checksum="5403E35AF7BB0664" modified="2008-04-29" version="1">MIYTFGHCHLNTKTHQLYVNDGLISLENRQFLLLQLLAKSGNQVVSRDHLLENLWPKQIVSDTSLSRLISDTRKLIGDDGKSQHIIKTCRGGGFMLVPPITMSDTEQPTLTSRRGIAVSVSLLGLLLLALTYLGYNAIPQKSDNYQLIITIQQQLDITKTAFIAQTKRRNELGKTLGIEAGGDILWEQVFSAAYPDLTKRQKFIFDQIRGITQGAMYNGNQAIADILQQNPDLKNQIASLGPLLSHLNYWLAKYQQVFLQREDMCLLYVGREDGVPFPSRVDKDVADWLAANKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN82</accession>
    <name>B1KN82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322928.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0278"/>
    <dbReference type="EnsemblBacteria" id="ACA84579">
        <property type="protein sequence ID" value="ACA84579"/>
        <property type="gene ID" value="Swoo_0278"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0278"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_1_4_6"/>
    <dbReference type="OMA" id="WHMAYTS"/>
    <dbReference type="OrthoDB" id="860559at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="291" mass="32606" checksum="5BD56901AA77A3B6" modified="2008-04-29" version="1">MLKIELLESFIAIAESGNLSKAAEKICRTQSALSLQIKKLEESVGQPLLHRDNKGVTLTASGKTLLNYAYKMMQLSSKALDDLKECQNRESIRLGVPTDYINRYLGSCLLEFIREFTCIELIIDTDVSGNLYKRLHNGEFDLIVATHWHPPAAGHGELLFERRFHWVAAKGGNAHKRETIPMALYPENCPIRAQVFANHQISMRPMSVLLSTPSPAAMCMAVENDLVIAPIAEFRINDKMQIIDPVEHNIPSLPVFNESLYLNPDTQTEATNQLIDLIKANVKELGEVPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNN8</accession>
    <name>B1KNN8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Carbamoyl-phosphate synthase L chain ATP-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3226</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325832.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3226"/>
    <dbReference type="EnsemblBacteria" id="ACA87496">
        <property type="protein sequence ID" value="ACA87496"/>
        <property type="gene ID" value="Swoo_3226"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3226"/>
    <dbReference type="eggNOG" id="COG4770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_1_6"/>
    <dbReference type="OMA" id="WQIWGDA"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="9">
        <location>
            <begin position="16"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="135"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="627"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="709" mass="77929" checksum="7F27053950E7A27F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP4</accession>
    <name>B1KNP4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325838.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87502">
        <property type="protein sequence ID" value="ACA87502"/>
        <property type="gene ID" value="Swoo_3232"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3232"/>
    <dbReference type="eggNOG" id="ENOG5031H95">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149363_0_0_6"/>
    <dbReference type="OMA" id="SYNVWRM"/>
    <dbReference type="OrthoDB" id="2038113at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16598" checksum="53AA413142857FA2" modified="2008-04-29" version="1">MRFSIKGDQPITVFQVTAVFSMIFALIGFSYNVWRMEITEYNSNMRSASFELLLQLSELEGIVYAAHYDQDKFEGNPRKGWIKVNLIADLSMIAEPEVKLSANALKQSWQENWQELAQSEESAQNVIEAIDSTRNSVRDLISQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNP8</accession>
    <name>B1KNP8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transfer flavoprotein alpha/beta-subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325842.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3236"/>
    <dbReference type="EnsemblBacteria" id="ACA87506">
        <property type="protein sequence ID" value="ACA87506"/>
        <property type="gene ID" value="Swoo_3236"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3236"/>
    <dbReference type="eggNOG" id="COG2086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060196_0_0_6"/>
    <dbReference type="OMA" id="YNGGMVP"/>
    <dbReference type="OrthoDB" id="1027643at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="3">
        <location>
            <begin position="23"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="249" mass="26786" checksum="E2C2DF6A19A880D5" modified="2008-04-29" version="1">MKVLVPVKRVVDANVKVRVNADNTGVDTANLKMAINPFCEIAVEEAVRLKEAGTASEIVVVTVGPKAAQEQLRTAMALGADRGIHIETDEELVPLSIAKLLLSVQEKEQAELILLGKQSIDGDNNQTGQMLAALAKMPQATFASEVKLEGESLAVTREIDGGLQTVTMPLPAVVTVDLRLNEPRYAKLPNIMKAKRKPLETVSIDDLGVSLKSHQKTLKVSPPSERQAGVMVSSVAELVEKLKNEAKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNV9</accession>
    <name>B1KNV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3297"/>
    <dbReference type="EnsemblBacteria" id="ACA87567">
        <property type="protein sequence ID" value="ACA87567"/>
        <property type="gene ID" value="Swoo_3297"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3297"/>
    <dbReference type="eggNOG" id="ENOG5033JKV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169029_0_0_6"/>
    <dbReference type="OMA" id="NKIPMPL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="109" mass="12018" checksum="6EE3003F1D683C27" modified="2008-04-29" version="1">MMSPLEQVLAAAKSITDAGKQPSLALIKTKLGNSVPMPILIQGLQQFKSMSQDAIEQLQALTADVSLSPKSEELSELDTLKLELKRLKEDYQQLNSRLTALESGYRSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ6</accession>
    <name>B1KNZ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sodium/glutamate symporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gltS</name>
        <name evidence="2" type="ordered locus">Swoo_4778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the sodium-dependent transport of glutamate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327344.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4778"/>
    <dbReference type="EnsemblBacteria" id="ACA89027">
        <property type="protein sequence ID" value="ACA89027"/>
        <property type="gene ID" value="Swoo_4778"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4778"/>
    <dbReference type="eggNOG" id="COG0786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040907_0_0_6"/>
    <dbReference type="OMA" id="MITICLM"/>
    <dbReference type="OrthoDB" id="1284248at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015501">
        <property type="term" value="F:glutamate:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015813">
        <property type="term" value="P:L-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02062">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004445">
        <property type="entry name" value="GltS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36178">
        <property type="entry name" value="PTHR36178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03616">
        <property type="entry name" value="Glt_symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00210">
        <property type="entry name" value="gltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0915">Sodium</keyword>
    <keyword evidence="1" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="1" id="KW-0769">Symport</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="407" mass="43727" checksum="3161549FD76F704E" modified="2008-04-29" version="1">MNTVYSIGELESFLVAILVLFIGHSINRHVPFFRKYNIPEPIVGGLIVAAIITILHFNNITLAFTLSMQKTLMLMFFSTVGLAANYKLLLKGGSKVFLFLGIASLFILIQNAVGVSMATALGLEPLMGLIAGSITLSGGHGTGVAWAHTFQENYGINTLEFAMAAATFGLVMGGIIGGPVAQRLINKNNLVSSYGVGGNHHKDHPDLVTYDQLEEDRVTAKSILEVMFILLLCVSGAKWVATLISSSGISWLKMPEFVYALFIGVVITNITELSHGYKIKSESVDVLGTVSLSLFLAMALMNLKLWEIFDLALPLLAILLVQTVTLALFAYFITFRLMGRNYDAAVMAGGHCGFGMGATPTAVMNMGALVSRTGPSPQAFMVVPIVGAFFIDIVNAIILQGYLSFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP97</accession>
    <name>B1KP97_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323016.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0367"/>
    <dbReference type="EnsemblBacteria" id="ACA84667">
        <property type="protein sequence ID" value="ACA84667"/>
        <property type="gene ID" value="Swoo_0367"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0367"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008878_4_0_6"/>
    <dbReference type="OMA" id="GGGTNCW"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="2">
        <location>
            <begin position="425"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="565" mass="62153" checksum="5E40CDFCCA076491" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPC1</accession>
    <name>B1KPC1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323040.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0392"/>
    <dbReference type="EnsemblBacteria" id="ACA84691">
        <property type="protein sequence ID" value="ACA84691"/>
        <property type="gene ID" value="Swoo_0392"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0392"/>
    <dbReference type="eggNOG" id="COG2930">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100198_0_0_6"/>
    <dbReference type="OMA" id="KGGLMYE"/>
    <dbReference type="OrthoDB" id="1808930at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764718" description="Ysc84 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Ysc84" evidence="2">
        <location>
            <begin position="88"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="19559" checksum="0BA79FE88163FF02" modified="2008-04-29" version="1" precursor="true">MKKLIRLISTLSLAASLMFTQAALADSEYSDTIAKFKQASDTHRFFDNAYGYAIFPTVGKGGLGIGAAYGKGQVFRNQSYTGDTSLTQISLGFQIGGQAYSEIIFFKNAKAYEEFTSGSFEFGAQASAVAINIGANAQAGTTGNSSGAGGKAAKAAYINGMAVYTMAKGGLMFEAALAGQSFTFEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE4</accession>
    <name>B1KPE4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mg chelatase, subunit ChlI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323063.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84714">
        <property type="protein sequence ID" value="ACA84714"/>
        <property type="gene ID" value="Swoo_0416"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0416"/>
    <dbReference type="HOGENOM" id="CLU_217274_1_0_6"/>
    <dbReference type="OrthoDB" id="581802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="38" mass="3980" checksum="7DFB0109B917285A" modified="2008-04-29" version="1">MAIACVATRASKGVDAPSVTVEVHLSNGLPAFSKDWHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPP2</accession>
    <name>B1KPP2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324541.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1911"/>
    <dbReference type="EnsemblBacteria" id="ACA86195">
        <property type="protein sequence ID" value="ACA86195"/>
        <property type="gene ID" value="Swoo_1911"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1911"/>
    <dbReference type="eggNOG" id="COG2374">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006338_0_1_6"/>
    <dbReference type="OMA" id="VEWHINA"/>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767282" evidence="1">
        <location>
            <begin position="22"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="3">
        <location>
            <begin position="16"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="782"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="940" mass="99738" checksum="8F39F3BCFD068BE1" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPS2</accession>
    <name>B1KPS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxaloacetate decarboxylase alpha subunit</fullName>
            <ecNumber evidence="4">4.1.1.112</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.112" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325940.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3336"/>
    <dbReference type="EnsemblBacteria" id="ACA87605">
        <property type="protein sequence ID" value="ACA87605"/>
        <property type="gene ID" value="Swoo_3336"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3336"/>
    <dbReference type="eggNOG" id="COG0511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5016">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_4_3_6"/>
    <dbReference type="OMA" id="GYHALEM"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005776">
        <property type="entry name" value="OadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01108">
        <property type="entry name" value="oadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="529"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="602" mass="65933" checksum="7DF5F6F42F112D5E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT5</accession>
    <name>B1KPT5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein FtsB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ftsB</name>
        <name evidence="4" type="ordered locus">Swoo_3349</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="3">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FtsB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325953.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3349"/>
    <dbReference type="EnsemblBacteria" id="ACA87618">
        <property type="protein sequence ID" value="ACA87618"/>
        <property type="gene ID" value="Swoo_3349"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3349"/>
    <dbReference type="eggNOG" id="COG2919">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134863_5_2_6"/>
    <dbReference type="OMA" id="YELGMVK"/>
    <dbReference type="OrthoDB" id="2014691at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00599">
        <property type="entry name" value="FtsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023081">
        <property type="entry name" value="Cell_div_FtsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37485">
        <property type="entry name" value="PTHR37485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="3"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="3">
        <location>
            <begin position="22"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="11395" checksum="48AF364B8BFE3CA3" modified="2008-04-29" version="1" precursor="true">MRRILLLLVSLLGMLQYQLWLGVNSLPESFQLREQISLQEASNAKLIARNQVLREEIIDLRSGTEALEERARNELGMVKKGETFFRVVGDKRTSQLSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPX7</accession>
    <name>B1KPX7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325995.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3392"/>
    <dbReference type="EnsemblBacteria" id="ACA87660">
        <property type="protein sequence ID" value="ACA87660"/>
        <property type="gene ID" value="Swoo_3392"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3392"/>
    <dbReference type="eggNOG" id="ENOG5032TMV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107941_1_0_6"/>
    <dbReference type="OMA" id="ISIHFCL"/>
    <dbReference type="OrthoDB" id="1566966at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019629">
        <property type="entry name" value="Uncharacterised_HI1736/YgjV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026267">
        <property type="entry name" value="YgjV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10688">
        <property type="entry name" value="Imp-YgjV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011443">
        <property type="entry name" value="YgjV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="171" mass="19231" checksum="AE1EAA6D3BDA54B5" modified="2008-04-29" version="1">MSLFIWSQVLIVIAIVFDIASFQFKQRQKIVACLSVSGLLISAHFILLEQWTAAGLMMLASIRYFSSIFSTSKRLMSMFLFYALMVTAATFSGLLSLLSFSGTVFQTTAAFCQSDQRLRQLMIVGTSLWLLHNYLAGSPTAVLMELIFIASNILGYYRYYGLRLVKITVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ28</accession>
    <name>B1KQ28_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 9">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glmS</name>
        <name evidence="12" type="ordered locus">Swoo_4892</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327458.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4892"/>
    <dbReference type="EnsemblBacteria" id="ACA89141">
        <property type="protein sequence ID" value="ACA89141"/>
        <property type="gene ID" value="Swoo_4892"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4892"/>
    <dbReference type="eggNOG" id="COG0449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_5_2_6"/>
    <dbReference type="OMA" id="TSYYSGC"/>
    <dbReference type="OrthoDB" id="43416at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 9 12" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="10">
        <location>
            <begin position="2"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="11">
        <location>
            <begin position="286"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="11">
        <location>
            <begin position="458"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="9">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="9">
        <location>
            <position position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA89141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="609" mass="66294" checksum="58559957A64A94BE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ60</accession>
    <name>B1KQ60_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Filamentation induced by cAMP protein Fic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4924</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327489.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4924"/>
    <dbReference type="EnsemblBacteria" id="ACA89173">
        <property type="protein sequence ID" value="ACA89173"/>
        <property type="gene ID" value="Swoo_4924"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4924"/>
    <dbReference type="eggNOG" id="COG3177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041789_0_0_6"/>
    <dbReference type="OMA" id="IWQQPDW"/>
    <dbReference type="OrthoDB" id="1232677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025230">
        <property type="entry name" value="DUF4172"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13776">
        <property type="entry name" value="DUF4172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="110"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="207"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="245"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="369" mass="41940" checksum="352088AD38BB42E6" modified="2008-04-29" version="1">MWIWQQADWPNFHWDSSKVSQLLRQINFNQGLLLGKLDQDPSVQITLDTLLANIIHSSAIEGEKLNAFSVRSSLANKLGVSDKKPFPTTVQTDGLAEMTLDALQNWQSELTLTRILNWHHLLFPEGHSLFNSIQGGTLRGEEPMQVVSGRIDKPKVHFEAPPRSILDGELEQFIAWFNHSRHDTDLDPLIRAAITHLWFVTLHPLDDGNGRITRLLTDLALTQAEHRSIRFYAMSVTVLERRQAYYEMLETSQKGELDITTWLVWFLDTLNASLQKSLDDIAQTIAKTNYWQRVDQTLSGKKLTTEQVKVLNRLLDGEFELGISSSQYQKVAKVSRATATRHLAQLVEQKCLVKADAGGRSTRYLLASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ62</accession>
    <name>B1KQ62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327491.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4926"/>
    <dbReference type="EnsemblBacteria" id="ACA89175">
        <property type="protein sequence ID" value="ACA89175"/>
        <property type="gene ID" value="Swoo_4926"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4926"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084474_0_0_6"/>
    <dbReference type="OMA" id="VPSMQML"/>
    <dbReference type="OrthoDB" id="1555988at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="28744" checksum="ECB968C066D7531E" modified="2008-04-29" version="1">MTETSKLKPTTNTAANPTSNYRKMTKAFIIGLPRSGTTSVSVALLEHGFKVAHQGFTKQTFELADIVSDAPCFSDYKQLARLYPQAKFIYLDRELEAWVPSMQMLLSRMLPHLDRKTGRFHPILKRSFSHSFGVGEVSDPMDGQHLVECYQRHKKAVFEFFCSVEQHQDNFMSINISEEGSLSKLLNFLSFESEQNASEMNFPHLNFPHLNFPHLNKGRNVASWDEYKHGNKISSNAAGPENRKFFDYKLI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQL8</accession>
    <name>TRHO_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name type="ordered locus">Swoo_1973</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324603.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQL8"/>
    <dbReference type="SMR" id="B1KQL8"/>
    <dbReference type="STRING" id="392500.Swoo_1973"/>
    <dbReference type="EnsemblBacteria" id="ACA86257">
        <property type="protein sequence ID" value="ACA86257"/>
        <property type="gene ID" value="Swoo_1973"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1973"/>
    <dbReference type="eggNOG" id="COG1054">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038878_0_0_6"/>
    <dbReference type="OMA" id="CDTHTNC"/>
    <dbReference type="OrthoDB" id="684577at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000200380" description="tRNA uridine(34) hydroxylase">
        <location>
            <begin position="1"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="123"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="332" mass="37607" checksum="B65D5FBAF2510FF5" modified="2008-04-29" version="1">MSQVVVCALYKFVSLPNFESIQKPLLAHMESAGIKGTLLLASEGINGTVAGSQLAIDNLLQWLAKQDGLDSIVHKLSFDETMPFYRTKVKLKKEIVTMGVEGIDPLKVVGTYVKPKDWNQLISDPEVLLVDTRNEYEVQIGTFKNAVDPKTDTFREFPAYVKEHLDPAKHKKVAMFCTGGIRCEKSTAYLKEQGFDEVYHLEGGVLKYLEEVKQEESLWEGECFVFDNRVAVNHALEKGQYDQCNACRMPITELEKASEAFVQGVSCPHCIDNISEKQRQRFEERERQMQLAAKRGEAHIGSDVGAVIQSRRDNKENLKKSQVKLNNKKYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR13</accession>
    <name>B1KR13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323178.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0533"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84830">
        <property type="protein sequence ID" value="ACA84830"/>
        <property type="gene ID" value="Swoo_0533"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0533"/>
    <dbReference type="eggNOG" id="COG1819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048991_0_0_6"/>
    <dbReference type="OMA" id="GFGHQYA"/>
    <dbReference type="OrthoDB" id="1165736at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005262">
        <property type="entry name" value="CHP00661"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00661">
        <property type="entry name" value="MJ1255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="350" mass="39332" checksum="92F174324A6E8FF2" modified="2008-04-29" version="1">MKILYGVQGTGNGHLSRARVMAKSLCKHGVDVDFFFSGRSPEQFFDMQCFGKYQVESGLTFATHHGRVNIAQTAWSNSVPSLINDIQSLDLSGYDLVLNDFEPVSAWAAKRQGVTSIGVSHQVALKYDVPKVGANWFNETLLNYFAPVDIALGCHWHHFGFPILPPFVEVEPVVSVNPHDILVYLPFEDPDAIVNFLAPFKEFKFYVYHSGKPLLRTPEHIKWSGFNRDEFKRRLSLCSGVIGCAGFELASEALTLGKRLLVKPLVGQFEQLSNVAALELLGAADTMLTLDGKQLQRWLKSAPPQPILYPQVGDELVKWLLSDDWHTGDKLCCQLWDKVELPMSWRKKNP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD2</accession>
    <name>Y2055_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0502 protein Swoo_2055</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_2055</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0502 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324684.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRD2"/>
    <dbReference type="SMR" id="B1KRD2"/>
    <dbReference type="STRING" id="392500.Swoo_2055"/>
    <dbReference type="EnsemblBacteria" id="ACA86339">
        <property type="protein sequence ID" value="ACA86339"/>
        <property type="gene ID" value="Swoo_2055"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2055"/>
    <dbReference type="eggNOG" id="COG3132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057831_2_0_6"/>
    <dbReference type="OMA" id="CNQKSSR"/>
    <dbReference type="OrthoDB" id="1721848at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01584">
        <property type="entry name" value="UPF0502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007432">
        <property type="entry name" value="DUF480"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38768">
        <property type="entry name" value="PTHR38768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04337">
        <property type="entry name" value="DUF480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000201258" description="UPF0502 protein Swoo_2055">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="219" mass="24792" checksum="18AAF62AF38F8819" modified="2008-04-29" version="1">MNLSLHEARIIGCLLEKEVTTPDQYPLSLNSLTLACNQKSSRDPVMSMTESETQSAIDSLMKKRLVTDQTGFGSRVTKYKHRFCNTEFSDLQFSPAQFALICLLLLRGPQTPGELKSRSGRLHQFADLNEVENALLALAQREPSLVHQLPKEPGRRDSRFEELISDQVKGESVPISEHSRSQREAPSKRQDEMDELTLRVSQLELEVKTLKEALQDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRL9</accession>
    <name>B1KRL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoside recognition domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326117.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3520"/>
    <dbReference type="EnsemblBacteria" id="ACA87784">
        <property type="protein sequence ID" value="ACA87784"/>
        <property type="gene ID" value="Swoo_3520"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3520"/>
    <dbReference type="eggNOG" id="COG3314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048533_0_0_6"/>
    <dbReference type="OMA" id="TSKQYEG"/>
    <dbReference type="OrthoDB" id="819609at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="2">
        <location>
            <begin position="137"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="451" mass="48838" checksum="F92E5FD68212B9D9" modified="2008-04-29" version="1" precursor="true">MAEKQNHNIKTILTFIIPSLIGLLLFMTPISYQDAITIPIAIVSKGLQALLGTWLTAIVTGVVCFTAIATVVTKLLKPIFVTQNGFLNSLLNVTPMWLIIRVLGAIFILLTFAQVGPEAIRSGDTGALVLNDLLPVLFCVFIFAGMLLPLLLNFGLLELFGTLLTKIMRPVFNLPGRSAIDCMASWLGDGSVGILMTSKQYEARFYTQREAAVIGTTFSAVSITFSLVVISQVKLEHMFVPFYLTVCFAGLMAAIIVPKLPPLSWKKDTYIDDTPRHPDDEVIPAGKGVLSWGVEQALNKASKAGGIKHTLTDGMKNVIDMVFGVIPVVMAIGTVALIVAEHTPIFDYLGMPFIPLLELLQVPEATAASKTIVVGFADMFLPSILASSIESDMTRFIIAAMSVTQLIYMSEVGALLIGSKIPVNILELFVVFILRTLVTLPIIAGVAHLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRM8</accession>
    <name>B1KRM8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3529</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326126.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3529"/>
    <dbReference type="EnsemblBacteria" id="ACA87793">
        <property type="protein sequence ID" value="ACA87793"/>
        <property type="gene ID" value="Swoo_3529"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3529"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_28_3_6"/>
    <dbReference type="OMA" id="EIKQESM"/>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="221"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="413" mass="45464" checksum="55E57AB334C3D80A" modified="2008-04-29" version="1">MSFSSMALSAELLNVLSELNYSEPTQVQAEAIPAILAGSDLMAGAQTGTGKTAAFALPILERLSQLKSSQTSYELTPVRALILTPTRELALQVHQSFVRYGDGLTLKSAIVYGGVSIDAQADILKAGVDILIATPGRLLDHLRRGSLTLTQLAFLVFDEADRMLDMGFKDEIDAILKQLPKERQTLLFSATFDDGVFNLSKRLLKDPKLIEVGKRNAAAGKVEQRVYAVDADRKSELLCHLILSKKWRQVLIFSRKKQGADKLAAKLVNEGVKALAFHGDLSQSVREKVLQEFKSGELQVLVATDVAARGLDVESLEVVVNYELPFVAEDYVHRIGRTGRAGNSGLAITLYCEDDALLLEEVEAVLDTRLPQQWLEGFEPDLTKSVSVTRKNSKSAQKQRARRRATGSKRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRN3</accession>
    <name>B1KRN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3534</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326131.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3534"/>
    <dbReference type="EnsemblBacteria" id="ACA87798">
        <property type="protein sequence ID" value="ACA87798"/>
        <property type="gene ID" value="Swoo_3534"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3534"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_6"/>
    <dbReference type="OMA" id="EMGSDDY"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="145"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="243" mass="27980" checksum="626BA90FEA7F6D68" modified="2008-04-29" version="1">MAYNVLVVDDESVIRARLKGYFEKEGYRVQQAQNGEQMWHEFNRQHIDLVILDINLQGSNGLNSGADGLSLTRELRSRSDVGIILVTGRDEAIDKIIGLEMGADDYVTKPFELRELLVRVKNLLWRISLVRQAEQKVIEQLEQKDDVIVFDGYALELNSRKLLHGEDLIKLTKAEFELLAAFALHPQQVLSRERLMQQTSHRNQDVNDRTIDVILRRLRNKLNPDLFVTVHGEGYLFSAKVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRP1</accession>
    <name>B1KRP1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326139.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3542"/>
    <dbReference type="ESTHER" id="shewm-b1krp1">
        <property type="family name" value="A85-IroE-IroD-Fes-Yiel"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87806">
        <property type="protein sequence ID" value="ACA87806"/>
        <property type="gene ID" value="Swoo_3542"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3542"/>
    <dbReference type="eggNOG" id="COG2819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039834_0_1_6"/>
    <dbReference type="OMA" id="DFQFQHV"/>
    <dbReference type="OrthoDB" id="1828423at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766995" evidence="1">
        <location>
            <begin position="23"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="412" mass="47022" checksum="585CC1DE90F8CDD6" modified="2008-04-29" version="1" precursor="true">MKSILITIAVTLVLLTSLNLNATSLDKTPIVSAYQYQHHSQILAQKRRYMVSLPERYQINQRDFPTLYIIDADFQFQHVSSIVKHLTRMGKLPPMIVVGIANQGDDDYLKTTTWPDGKDDAFGGAAQFHTYLKQELLPTIDAQFRTDDRKALAGYSLGGLFTLYSMMQMQTPFNAFLAMSPSAWHDGNSLPGKIESLLKQGKITSPVFISLANEEGMGVEKLIQVFEQAAPAKLNWQYKHYPNENHFTTALPALYDGLQFLAPDYAIDGTDMLAIGDYKQVLTHFSQQQENWAGFQFEWLTAYQFAKYLFWSKQLDEVDNVLKAVKTQFPESFANVSIQLAKGFNKKQDFKRVAQLLNGVKAEGETLPGWHKQMSIYYKSTDKPELAKQHQEQALMLAKKYDLESWEVWELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRS6</accession>
    <name>B1KRS6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="13">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">carB</name>
        <name evidence="17" type="ordered locus">Swoo_3577</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326174.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3577"/>
    <dbReference type="EnsemblBacteria" id="ACA87841">
        <property type="protein sequence ID" value="ACA87841"/>
        <property type="gene ID" value="Swoo_3577"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3577"/>
    <dbReference type="eggNOG" id="COG0458">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000513_1_0_6"/>
    <dbReference type="OMA" id="IEPAGIH"/>
    <dbReference type="OrthoDB" id="48855at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_A">
        <property type="entry name" value="CPSase_L_chain_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="133"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="678"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="16">
        <location>
            <begin position="936"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="13">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Oligomerization domain" evidence="13">
        <location>
            <begin position="404"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="13">
        <location>
            <begin position="936"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="828"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="840"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="842"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA87841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1072" mass="117900" checksum="522DCC9DACF2C557" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCY3</accession>
    <name>B1KCY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0011"/>
    <dbReference type="EnsemblBacteria" id="ACA84312">
        <property type="protein sequence ID" value="ACA84312"/>
        <property type="gene ID" value="Swoo_0011"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0011"/>
    <dbReference type="eggNOG" id="COG1639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060732_0_0_6"/>
    <dbReference type="OMA" id="WRANVIS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="2">
        <location>
            <begin position="86"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="334" mass="37322" checksum="A489353FC826E3FE" modified="2008-04-29" version="1">MPKALSTDLGFQTLSSTPKKEPLKSKAPSSEPLKLERRVDVSALFYGMLFPSQSGAETGIANNLEKSVISEVENALTSPADIAEKVLKLPSQLAVLDQKLKDDSVDIETLLEVFKTKPVLSIEVLKLCNSPAFKRSDKEVTNLQQAFVQLGREQIRRLVTTSLMGEIVEIKPIYYRRFGLQIWRHSQQVSYLSAEFGKCDPDTAFMLGLLHDVGKIAIFKMLLDAFQLAEPGEQPSSSLFKQVMTTKSLSLSALLAKHWQLPAIFETSLSQLASSHSKPSDELALAVWRANLISECSMLLQANQLDEDDLSRLLMDAGLTREQFDTYHERLKMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD12</accession>
    <name>B1KD12_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable GTP-binding protein EngB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">engB</name>
        <name evidence="10" type="ordered locus">Swoo_0058</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for normal cell division and for the maintenance of normal septation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0058"/>
    <dbReference type="EnsemblBacteria" id="ACA84359">
        <property type="protein sequence ID" value="ACA84359"/>
        <property type="gene ID" value="Swoo_0058"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0058"/>
    <dbReference type="eggNOG" id="COG0218">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033732_1_0_6"/>
    <dbReference type="OMA" id="LMMDIRH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="9">
        <location>
            <begin position="26"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="24711" checksum="BCEF7FDAD422929D" modified="2008-04-29" version="1">MDFRKAKFLISAPDIAHLNQYLPGDAGVEIAFAGRSNAGKSSALNMLTDQKGLARTSKTPGRTQLINVFELDEHRRLVDLPGYGFAQVPLALKKKWQYALGEYLQERQCLTGVVVLMDIRHPLKDLDMQMIEWAVESEIPVLALLTKADKMKQSERMKMINEVRKHLGDYDDRVKVEAFSSLKGLGKPKVLSILNEWCHPEWLMEAIAEAEAADESEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD34</accession>
    <name>B1KD34_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_3605</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326202.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3605"/>
    <dbReference type="EnsemblBacteria" id="ACA87869">
        <property type="protein sequence ID" value="ACA87869"/>
        <property type="gene ID" value="Swoo_3605"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3605"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_19_6"/>
    <dbReference type="OMA" id="YHARGSN"/>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="335"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="394"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA87869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="666" mass="73560" checksum="CBE3BE09BABAD23F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD61</accession>
    <name>LUXD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acyl transferase</fullName>
            <shortName evidence="1">ACT</shortName>
            <ecNumber evidence="1">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">C14ACP-TE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Myristoyl-ACP-specific thioesterase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">luxD</name>
        <name type="ordered locus">Swoo_3634</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid reduction for biolumincescence.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LuxD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326229.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KD61"/>
    <dbReference type="SMR" id="B1KD61"/>
    <dbReference type="STRING" id="392500.Swoo_3634"/>
    <dbReference type="ESTHER" id="shewm-luxd">
        <property type="family name" value="Thioesterase_acyl-transferase"/>
    </dbReference>
    <dbReference type="PRIDE" id="B1KD61"/>
    <dbReference type="EnsemblBacteria" id="ACA87896">
        <property type="protein sequence ID" value="ACA87896"/>
        <property type="gene ID" value="Swoo_3634"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3634"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_882365_0_0_6"/>
    <dbReference type="OMA" id="FARRMDH"/>
    <dbReference type="OrthoDB" id="631878at2"/>
    <dbReference type="UniPathway" id="UPA00569"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008218">
        <property type="term" value="P:bioluminescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00774">
        <property type="entry name" value="LuxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003157">
        <property type="entry name" value="LuxD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02273">
        <property type="entry name" value="Acyl_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009416">
        <property type="entry name" value="LuxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0455">Luminescence</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000200689" description="Acyl transferase">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00774"/>
        </source>
    </evidence>
    <sequence length="305" mass="34556" checksum="204C5016AFB58F7F" modified="2008-04-29" version="1">MTNEDTFSTIDHAINLETGKTIRVWETFPKDNSLVKNNTILIASGFARRMDHFAGLAEYLSSNGFHVIRYDSLHHVGLSSGNINEFSMTIGKKSLLTVIEWLKRRNINKFGLIAASLSARIAYDVANEIDLSFLVTAVGVVNLRDTLERALKYDYLQLPIEELPEDLDFEGHNLGSEIFVTDCFKHQWDTFNSTKNKMKDLNIPFIAFTANDDSWVKQNEVLELIESLNPEKCQLYSLIGSSHDLGENLVVLRNFYQSVTKAAIALDKGSLNLDINIIEPKFEDITSVTVKERRLKHNIESLELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD5</accession>
    <name>B1KDD5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323283.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0640"/>
    <dbReference type="EnsemblBacteria" id="ACA84936">
        <property type="protein sequence ID" value="ACA84936"/>
        <property type="gene ID" value="Swoo_0640"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0640"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_0_1_6"/>
    <dbReference type="OMA" id="GQMQERT"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="111"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Important for interaction with partner proteins" evidence="2">
        <location>
            <begin position="220"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="111"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="24892" checksum="F6F5D29545F31799" modified="2008-04-29" version="1">MASRGVNKVILVGNLGKDPEVRYMPNGNAVANFTVATSESWKDQQGQPQERTEWHNIVMYRRLAEVAGEYLKKGSKVYIEGKLQTSKWQDQATGQDRYKTEINANEMQMLDSRGQGGGQQQGGYGQQQGQQNQYNAPQQQAPQQGGYAPKPQAAPQQQAPQQGGYQSQQQGGQQQQAPAYAPKPQAAPQQQAPQQRPAPQPQQQAAPQQNFTPDLDDGWDDDIPF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDR7</accession>
    <name>KDSB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.90</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kdsB</name>
        <name type="ordered locus">Swoo_2182</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + CTP = CMP-8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49284"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:87091"/>
            <dbReference type="ChEBI" id="CHEBI:91089"/>
            <dbReference type="EC" id="2.7.7.90"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KdsB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.90" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324808.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDR7"/>
    <dbReference type="SMR" id="B1KDR7"/>
    <dbReference type="STRING" id="392500.Swoo_2182"/>
    <dbReference type="EnsemblBacteria" id="ACA86464">
        <property type="protein sequence ID" value="ACA86464"/>
        <property type="gene ID" value="Swoo_2182"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2182"/>
    <dbReference type="eggNOG" id="COG1212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065038_0_1_6"/>
    <dbReference type="OMA" id="MSIKEHE"/>
    <dbReference type="OrthoDB" id="1345588at2"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000370161" description="8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <sequence length="245" mass="27314" checksum="33A4EE4DDE8CA993" modified="2008-04-29" version="1">MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTAIYVATDDDRIKEAVEAFGGKVVMTDPQAASGTDRIEDAITQLGLKDDDLIVNLQGDQPLIDPISIEQVITLFERHPGEFSMATLGVEITEKAELDDPKHVKMVFDNNFNALYFSRARIPFGRDTNDYPVYKHLGIYAYTRSFISTFAKLPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSPEVDTPEDIRICEARLAVD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU5</accession>
    <name>LOLB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Outer-membrane lipoprotein LolB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lolB</name>
        <name type="ordered locus">Swoo_3687</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LolB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326279.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDU5"/>
    <dbReference type="SMR" id="B1KDU5"/>
    <dbReference type="STRING" id="392500.Swoo_3687"/>
    <dbReference type="EnsemblBacteria" id="ACA87947">
        <property type="protein sequence ID" value="ACA87947"/>
        <property type="gene ID" value="Swoo_3687"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3687"/>
    <dbReference type="eggNOG" id="COG3017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092816_1_0_6"/>
    <dbReference type="OMA" id="YQTRGSF"/>
    <dbReference type="OrthoDB" id="1797257at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044874">
        <property type="term" value="P:lipoprotein localization to outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16326">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00233">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004565">
        <property type="entry name" value="OM_lipoprot_LolB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03550">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00548">
        <property type="entry name" value="lolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0998">Cell outer membrane</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0449">Lipoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0564">Palmitate</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_1000100510" description="Outer-membrane lipoprotein LolB">
        <location>
            <begin position="25"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="N-palmitoyl cysteine" evidence="1">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="S-diacylglycerol cysteine" evidence="1">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00233"/>
        </source>
    </evidence>
    <sequence length="213" mass="24039" checksum="CFCED0F481487288" modified="2008-04-29" version="1" precursor="true">MNNLSYFTKTKLVWVILSLSLLSACATKTPDNLIPVQVNHVSQAQAWEMQGKLAVRTADDKFSTNLYWLHTADINELKLTTMLGTTLLSLTTEEGVAKLEVDGKVYQHDDAQELLTEITGWSIPVNALPLWITGQAAQDDKIINQDLQLRPTVLLSEKDSPPWRVEFNSWQKQSGAEIPRLLELTREQLRLKIQISQWQALSATTLATNNQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE14</accession>
    <name>B1KE14_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3757</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326348.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3757"/>
    <dbReference type="EnsemblBacteria" id="ACA88016">
        <property type="protein sequence ID" value="ACA88016"/>
        <property type="gene ID" value="Swoo_3757"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3757"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_381677_0_0_6"/>
    <dbReference type="OMA" id="QMTVLPY"/>
    <dbReference type="OrthoDB" id="172665at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="8">
        <location>
            <begin position="479"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="722" mass="79533" checksum="533D9A75BD5E4F80" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE31</accession>
    <name>B1KE31_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage shock protein A, PspA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323364.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0722"/>
    <dbReference type="EnsemblBacteria" id="ACA85017">
        <property type="protein sequence ID" value="ACA85017"/>
        <property type="gene ID" value="Swoo_0722"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0722"/>
    <dbReference type="eggNOG" id="COG1842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102201_0_0_6"/>
    <dbReference type="OMA" id="QQMLRTI"/>
    <dbReference type="OrthoDB" id="1886134at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="89"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="228" mass="25431" checksum="0A6718BB4C76B3D4" modified="2008-04-29" version="1">MGILNKIITAFRGGATEVGQSIVDANSTRIFEQEIRDAENHLTKAKRELTDVMAKEMQASREVDRLKRSISEHEGYATQALEKENEALAMEVAEKISQLDQELAEQQSANANFTAHATRLKELVRKTERQLTDYQRQLSMVKTTESVQKATASITDSFAGSSSKLLNAKDSLERIKARQQQFDDRLVAAEQLADENSDKSLHDKLAQAGIGEQKSNANAVLDRLKARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEF2</accession>
    <name>B1KEF2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PqqA peptide cyclase</fullName>
            <ecNumber evidence="7">1.21.98.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Coenzyme PQQ synthesis protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pqqE</name>
        <name evidence="9" type="ordered locus">Swoo_2249</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[PQQ precursor protein] + S-adenosyl-L-methionine = 5'-deoxyadenosine + E-Y cross-linked-[PQQ precursor protein] + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:56836"/>
            <dbReference type="Rhea" id="RHEA-COMP:14800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:141026"/>
            <dbReference type="ChEBI" id="CHEBI:141027"/>
            <dbReference type="EC" id="1.21.98.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with PqqD. The interaction is necessary for activity of PqqE.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the radical SAM superfamily. PqqE family.</text>
    </comment>
    <dbReference type="EC" id="1.21.98.4" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324873.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2249"/>
    <dbReference type="EnsemblBacteria" id="ACA86530">
        <property type="protein sequence ID" value="ACA86530"/>
        <property type="gene ID" value="Swoo_2249"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2249"/>
    <dbReference type="eggNOG" id="COG0535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009273_4_7_6"/>
    <dbReference type="OMA" id="GWGRQFF"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009975">
        <property type="term" value="F:cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00660">
        <property type="entry name" value="PqqE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011843">
        <property type="entry name" value="PQQ_synth_PqqE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017200">
        <property type="entry name" value="PqqE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13186">
        <property type="entry name" value="SPASM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037420">
        <property type="entry name" value="PQQ_syn_pqqE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00280">
        <property type="entry name" value="coenzyme_PQQ_synthesis_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02109">
        <property type="entry name" value="PQQ_syn_pqqE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04085">
        <property type="entry name" value="rSAM_more_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 7" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="7"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="371" mass="41601" checksum="0514B16A1B9219CA" modified="2008-04-29" version="1">MSENTSVGPPLWLLAELTYECPLHCAYCSNPTDLGKREDELTTEAWLDVLSQARELGSVQLGFSGGEPLLRKDLEILVEHGRKLGFYTNLITSGIGLTEKRIKQLKLAGLDHIQISFQAADPQLNDAIAGRGKAFEQKLKMAEVVKSEGYPMVLNFVISKQNIAQIPQILALSCQLDADYVELATAQYYGWAYDNRDHLLPSQAQLRQAEETVNQFRAQQDNKGPQFIFVTPDYYEDRPKACMNGWGSTFLTITPDGSALPCHSAKILPLTFPNVMDKTVTEIWQNDFSFNHFRGESWMPKPCKDCDEKEKDFGGCRCQAFMLTGDMNRTDPVCSKSEDHHLIAQAIEQASAPKNAIKHRKRVADIALVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEJ4</accession>
    <name>B1KEJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324914.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2293"/>
    <dbReference type="EnsemblBacteria" id="ACA86572">
        <property type="protein sequence ID" value="ACA86572"/>
        <property type="gene ID" value="Swoo_2293"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2293"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028527_0_0_6"/>
    <dbReference type="OMA" id="VHEAMPG"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="591" mass="67945" checksum="2DB41FDD2CF72639" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEL3</accession>
    <name>B1KEL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9B dipeptidylpeptidase IV domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3769</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326360.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3769"/>
    <dbReference type="ESTHER" id="shewm-b1kel3">
        <property type="family name" value="DPP4N_Peptidase_S9"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88028">
        <property type="protein sequence ID" value="ACA88028"/>
        <property type="gene ID" value="Swoo_3769"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3769"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006105_2_1_6"/>
    <dbReference type="OMA" id="VTHMTPQ"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766502" evidence="1">
        <location>
            <begin position="24"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="3">
        <location>
            <begin position="158"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="572"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="768" mass="87304" checksum="B46CFE99077FAD32" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEP2</accession>
    <name>B1KEP2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase-binding transcription factor DksA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dksA</name>
        <name evidence="8" type="ordered locus">Swoo_3798</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts directly with the RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DksA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326388.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3798"/>
    <dbReference type="EnsemblBacteria" id="ACA88057">
        <property type="protein sequence ID" value="ACA88057"/>
        <property type="gene ID" value="Swoo_3798"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3798"/>
    <dbReference type="eggNOG" id="COG1734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043144_2_0_6"/>
    <dbReference type="OMA" id="KKGEEYM"/>
    <dbReference type="OrthoDB" id="1932026at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00926">
        <property type="entry name" value="DksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012784">
        <property type="entry name" value="DksA_RNA_pol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020458">
        <property type="entry name" value="Znf_DskA_TraR_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02420">
        <property type="entry name" value="dksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01102">
        <property type="entry name" value="ZF_DKSA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="7">
        <location>
            <begin position="67"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="6">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="44"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="16894" checksum="27F4B37844893853" modified="2008-04-29" version="1">MPEGTKKLGVLAIAGVEPYQEKPGEEYMNADQLGHFRTILDAWRNQLREEVDRTLNHMQDEAANFPDPVDRAAQEEEFSLELRARDRERKLIKKIEKTLQKIEEDDFGFCDSCGIEIGIRRLEARPTADQCIDCKTLAEIKEKQMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER4</accession>
    <name>B1KER4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase</fullName>
            <ecNumber evidence="6">6.3.2.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Murein peptide ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mpl</name>
        <name evidence="10" type="ordered locus">Swoo_3820</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:29563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61401"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. Mpl subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.45" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326410.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3820"/>
    <dbReference type="EnsemblBacteria" id="ACA88079">
        <property type="protein sequence ID" value="ACA88079"/>
        <property type="gene ID" value="Swoo_3820"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3820"/>
    <dbReference type="eggNOG" id="COG0773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028104_0_1_6"/>
    <dbReference type="OMA" id="SGIAWDH"/>
    <dbReference type="OrthoDB" id="307881at2"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106418">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02020">
        <property type="entry name" value="Mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005757">
        <property type="entry name" value="Mpl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01081">
        <property type="entry name" value="mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="7">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="9">
        <location>
            <begin position="112"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="8">
        <location>
            <begin position="321"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="114"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="461" mass="50374" checksum="81432FD4EFCAD85F" modified="2008-04-29" version="1" precursor="true">MHVHILGICGTFMGGLALLARAEGHKVTGSDTNVYPPMSTQLEEQGIELIQGFDPSQLGESEDDAPDLVVIGNAMSRGNTCVEAVLNRGISYTSGPQFLAEHILKNRWVLAVSGTHGKTSTSSMLAWILEYCGYEPGFLIGGVPQNFGVSARTGNSPFFVVEADEYDSAFFDKRSKFVHYQPRTLVINNLEFDHADIFDDLKAIQRQFNHVIRTVPGEGKIIWPKESQAVTEVIKMGCWSEQEFYSSSADTGQAGWSTKLIADDGHQFELFFDGVSQGTLDWQLIGQHNVENATMAVAAARHVGVKPQAAIEALVKFQPPKRRMELIGTVNGIEVYDDFAHHPTAIATTLQGTRAKVGEGKITIILEPRSNTMKSGVHKDTLAGSMALANEAYLYQADNIDWDLASAMNKAELPVKVLYEIDEIVETVAEKAESGDTIVVMSNGGFGGLHQKLLKKLNAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF38</accession>
    <name>B1KF38_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xerD</name>
        <name evidence="15" type="ordered locus">Swoo_0895</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0895"/>
    <dbReference type="EnsemblBacteria" id="ACA85189">
        <property type="protein sequence ID" value="ACA85189"/>
        <property type="gene ID" value="Swoo_0895"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0895"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_9_0_6"/>
    <dbReference type="OMA" id="QAFWYLI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01807">
        <property type="entry name" value="Recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011932">
        <property type="entry name" value="Recomb_XerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02225">
        <property type="entry name" value="recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="13"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="119"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA85189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="308" mass="34624" checksum="1E0F6861699ADEC2" modified="2008-04-29" version="1">MSQSDNNIVPVQHKSDPLIELFLDDLWSSRGLSSNTLSAYRTDLCHFEHYLIKSGIALCDATQGTIRDYLDVRFEKGFARTSSARLISSLRRFYGFLVIQNRIEVDPTAQIKSPQLARKLPDSLSEADVDSLLSEPNLDDPIECRDKAMLELLYATGLRVTELVSLTMEQISLRQGVVRVVGKGGKERLVPLGEMAISEVESYLVAARGELLKQKMSDVLFPSKRGSMMTRQTFWHRIKHYALRAGISTDLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVAKARLSQLHSEHHPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF77</accession>
    <name>B1KF77_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAD-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324960.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2339"/>
    <dbReference type="EnsemblBacteria" id="ACA86618">
        <property type="protein sequence ID" value="ACA86618"/>
        <property type="gene ID" value="Swoo_2339"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2339"/>
    <dbReference type="eggNOG" id="COG5620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082934_2_1_6"/>
    <dbReference type="OMA" id="CFGYTPL"/>
    <dbReference type="OrthoDB" id="1681112at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015002">
        <property type="entry name" value="DUF1851"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014983">
        <property type="entry name" value="GAD-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08906">
        <property type="entry name" value="DUF1851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08887">
        <property type="entry name" value="GAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAD-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1851" evidence="2">
        <location>
            <begin position="130"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="221" mass="25066" checksum="EF263C031E6D4A07" modified="2008-04-29" version="1">MNKFFDNFYNFAGFGPAVKSKQPTAEELEFFEDKLPNRLLEYWQEYGFCGWGEGLIWVVNPADYADILMTWLSDTPFENADNYYVIARSAFGELIVWGEKTGQSIDINVNFGMIFPTDNTEKLKKRGEERSIELFFASMSKDSLDKKDLDENPLFERAMAKLGPLEADEMYGFVPALAIGGAPKLENLQKVKVLEHLTFLADLGEKTVMADIVAMSNALHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFB4</accession>
    <name>B1KFB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2376</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2376"/>
    <dbReference type="EnsemblBacteria" id="ACA86655">
        <property type="protein sequence ID" value="ACA86655"/>
        <property type="gene ID" value="Swoo_2376"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2376"/>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1118603_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767306" evidence="5">
        <location>
            <begin position="24"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="24"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="134"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="24908" checksum="B1F06D9D354AF606" modified="2008-04-29" version="1" precursor="true">MKISNVFILIAYLLLTSSMTIEAKNLDSGAEIYSDRCVLCHGNKGMGDGYIPMRLKGYPQTSLFESPKATDKTALVKVISKGVLIDTVNEYMPPWESELTEEQISDLADFVSYLRSDTENALIMLEKHTRKLDKTVRDGRVIFETRCALCHGKLGLGDGRMARIIKNPPPADLTKSILTPHQMGLIIKLGGQEVGRSPKMPPWGDFMTDNEVNAVVDFIDTLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN5</accession>
    <name>B1KFN5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0907</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323548.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0907"/>
    <dbReference type="EnsemblBacteria" id="ACA85201">
        <property type="protein sequence ID" value="ACA85201"/>
        <property type="gene ID" value="Swoo_0907"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0907"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_6_4_6"/>
    <dbReference type="OMA" id="WATRFEQ"/>
    <dbReference type="OrthoDB" id="1383885at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="86"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="23272" checksum="C5216E1F3638F686" modified="2008-04-29" version="1">MIKLYGVPRSRSLRVSWTLEELGLDWQYHFINFAKGDSRSESFLAVNPCGKVPALVDNDLVVTESAAIVLHLAEKYGDRKLLPTLGSDASALHHQWVSFIICELEQPLWTIGKHKFALPEEIRQQSMFAVAKWEFDKAAAIAENWLPDSDFLLGDKLSAADILLGHTLLWATRFEQDIPPKLAAYRDRVTARPTMVKALEKEVAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFP4</accession>
    <name>B1KFP4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0917</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323557.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0917"/>
    <dbReference type="EnsemblBacteria" id="ACA85210">
        <property type="protein sequence ID" value="ACA85210"/>
        <property type="gene ID" value="Swoo_0917"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0917"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_11_1_6"/>
    <dbReference type="OMA" id="HVSQSRM"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="25586" checksum="0BEA062A705FBEA4" modified="2008-04-29" version="1">MSDFIYSPPTTPWLEIIYQDKDILVVNKPSGLLSVPGRDPAHRDSIYARVLAEYPNAQVVHRLDMATSGIIVLALRRNAEKELKRQFRERETKKTYYARVAGHIRSDSGKVELPLICDWPNRPKQKVDHKVGKPSLTHYEVISRAKRSTLVKLTPITGRSHQLRVHMLAIGHPILGDNFYADPLAKSLASRLLLHAQELTIKQPYSGETLTFTCEVPFLEPETEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT7</accession>
    <name>B1KFT7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323600.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0960"/>
    <dbReference type="EnsemblBacteria" id="ACA85253">
        <property type="protein sequence ID" value="ACA85253"/>
        <property type="gene ID" value="Swoo_0960"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0960"/>
    <dbReference type="eggNOG" id="COG2236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080904_1_2_6"/>
    <dbReference type="OMA" id="QEYFDFK"/>
    <dbReference type="OrthoDB" id="1819460at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="12"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="21291" checksum="764AE20095AE15CA" modified="2008-04-29" version="1">MSDKRFITAQELLEDSFRLAAQVYESGFRPQFIVGIWRGGAPIGIAVQEYFDFKEVETDHIAVRTSSYYGIGTDKQSKQIKVHGLHYIVENANADDGLLIVDDVFDSGRSIHALMENLSDLMRLNLPKDVRIACPYYKPKNTAVPLKPDYFIHESDEWLVFPHEVSGLTPQELAEGKGDLKNIKELFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV5</accession>
    <name>B1KFV5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323618.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0978"/>
    <dbReference type="EnsemblBacteria" id="ACA85271">
        <property type="protein sequence ID" value="ACA85271"/>
        <property type="gene ID" value="Swoo_0978"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0978"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066901_0_1_6"/>
    <dbReference type="OMA" id="LIVTEHY"/>
    <dbReference type="OrthoDB" id="1860541at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="180" mass="20241" checksum="65217B005258358D" modified="2008-04-29" version="1">MLNPQECVLVVVDVQGKLAQVMDSSAELHQTLLNLIKGTALFDIPTLWLEQLPDKLGQTSPLLYQELIKQSSPIAKQHFSGWQAEQFKDQLTALNRTQILLVGIESHVCVYQTCSDLLENDFDVHLIVDAISSRTAANKQLGIEMMQHKGAQISNMESLLFELQHEAVGERFKALLKFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG69</accession>
    <name>B1KG69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Multiple resistance and pH regulation protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3949</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326536.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3949"/>
    <dbReference type="EnsemblBacteria" id="ACA88206">
        <property type="protein sequence ID" value="ACA88206"/>
        <property type="gene ID" value="Swoo_3949"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3949"/>
    <dbReference type="eggNOG" id="COG2212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125825_2_1_6"/>
    <dbReference type="OMA" id="GPTMQDR"/>
    <dbReference type="OrthoDB" id="2083248at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007208">
        <property type="entry name" value="MrpF/PhaF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34702">
        <property type="entry name" value="PTHR34702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04066">
        <property type="entry name" value="MrpF_PhaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="98" mass="10802" checksum="31749ED0DE2C9172" modified="2008-04-29" version="1" precursor="true">MLAAATIAILVVMLLAIARCIIGPTLYDRILAFNMFGTKTVLLISVLGFLMGRPEFLDIALVYALINFISVVGVLRFSDSAEFKVTPYERQSTKEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG95</accession>
    <name>B1KG95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MltA-interacting MipA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MipA/OmpV family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326562.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3975"/>
    <dbReference type="EnsemblBacteria" id="ACA88232">
        <property type="protein sequence ID" value="ACA88232"/>
        <property type="gene ID" value="Swoo_3975"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3975"/>
    <dbReference type="eggNOG" id="COG3713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063465_1_1_6"/>
    <dbReference type="OMA" id="EGNTYIR"/>
    <dbReference type="OrthoDB" id="1497770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010583">
        <property type="entry name" value="MipA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38776">
        <property type="entry name" value="PTHR38776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06629">
        <property type="entry name" value="MipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767036" evidence="5">
        <location>
            <begin position="20"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="257" mass="27973" checksum="9F573052B55802CB" modified="2008-04-29" version="1" precursor="true">MKKLCFAISAVLLSSHAFAADNTYIRNGNIYSHQGKFFAGAGVATGSELYKGQDNTTGVYFNGGYHGEDFNADLAGINYRFLGDNNSKINFSVFAVGNPGFDAKDADVLAGMKDRKVSGDLGLNVDIRLGNGTLSTKFQHDVTDVYGGYQADITYYLPMNIGFADIVPYAGVHYFSQDYVDYYTGVSKADATTKRPEFKGKDAFTYQAGYVMVVPITDHLDITQAAGYSHLTSEIADSPLVDSKNQWITTLGVSYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE3</accession>
    <name>B1KGE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ion transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4024</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326609.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88280">
        <property type="protein sequence ID" value="ACA88280"/>
        <property type="gene ID" value="Swoo_4024"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4024"/>
    <dbReference type="eggNOG" id="ENOG502Z7ZD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055047_0_1_6"/>
    <dbReference type="OMA" id="YTLFQVM"/>
    <dbReference type="OrthoDB" id="1280139at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043227">
        <property type="term" value="C:membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005261">
        <property type="term" value="F:cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003915">
        <property type="entry name" value="PKD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="PTHR10037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01433">
        <property type="entry name" value="POLYCYSTIN2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="6">
        <location>
            <begin position="19"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="282" mass="31276" checksum="30ECC12E1DB8C18C" modified="2008-04-29" version="1">MLANVSGLQSKLKLIDNSKAFQGFVIFVIIVSALSIGAHTYHLPTWMEQSLVVLDVGITVFFAIEIVIRFLASDGPKKFFSNGWNIFDTLIVIGSLIPAGGAGILIARLLRIFRVLRLVSMIPELRMLVNALLKAIPRMGYIALLMFVIFYIYGAIGSMLFAHINDFLWGDVSVAMLTLFRVSTFESWTSVMYETMAVYPLSWLYYLSFIFLTAFVFLNMMVGAVLDVMTQETQAMREEEADELALESGKSAEVDKPASAADVAELKAQIAELKGMLIQKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE8</accession>
    <name>B1KGE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326614.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4029"/>
    <dbReference type="EnsemblBacteria" id="ACA88285">
        <property type="protein sequence ID" value="ACA88285"/>
        <property type="gene ID" value="Swoo_4029"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4029"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120803_0_0_6"/>
    <dbReference type="OMA" id="LLTINAW"/>
    <dbReference type="OrthoDB" id="1923458at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="18453" checksum="90A3EA764E9ADE9F" modified="2008-04-29" version="1">MMPFLQRALVNSLRKVSADLFFEVLNNELAKGYSIRLFTLTEIDHLGGQAKRIYSSAPKQYPIGGYKQIEINDWSKQVLEQGEAFIANTEKALSEVFFDHQLISSMGLGAVINWPVIVEGKVIGTVNILSSENSYLDCDLEQFEALYPWFVIAFSLPVLQESSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGN8</accession>
    <name>B1KGN8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P460</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323712.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1073"/>
    <dbReference type="EnsemblBacteria" id="ACA85366">
        <property type="protein sequence ID" value="ACA85366"/>
        <property type="gene ID" value="Swoo_1073"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1073"/>
    <dbReference type="eggNOG" id="ENOG50300UA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106310_0_0_6"/>
    <dbReference type="OMA" id="PGNWAYF"/>
    <dbReference type="OrthoDB" id="1212262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032033">
        <property type="entry name" value="Cytochrome_P460"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038142">
        <property type="entry name" value="Cytochrome_P460_sp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16694">
        <property type="entry name" value="Cytochrome_P460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766587" evidence="1">
        <location>
            <begin position="26"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_P460" evidence="2">
        <location>
            <begin position="39"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="22697" checksum="F1B919ACF5A3722A" modified="2008-04-29" version="1" precursor="true">MNTIKMLLLSTITCAPLLFTGSVEAKQAYEFKNGELTRPTGYREWVYVGTPVTPNDMNNGKAAFPEHHNVYIDPKSWAHWKKTGKFRDGTILIKELVSVGSKAAVSGQGYFQGEFIGLEATIKSKADFPNEPGNWAYFSFSGEGHKTLTKTAKAFPSAACNGCHLVSAADDFVFTQYYPVLSAGKGTGKNATGGHLNDLKNSYVEPGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGY3</accession>
    <name>B1KGY3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4039</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326624.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4039"/>
    <dbReference type="EnsemblBacteria" id="ACA88295">
        <property type="protein sequence ID" value="ACA88295"/>
        <property type="gene ID" value="Swoo_4039"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4039"/>
    <dbReference type="eggNOG" id="COG4774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_15_0_6"/>
    <dbReference type="OMA" id="WQVGAFY"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="43"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="290"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="758" mass="84304" checksum="17FBF48C819EA63A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGZ5</accession>
    <name>B1KGZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326636.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4051"/>
    <dbReference type="EnsemblBacteria" id="ACA88307">
        <property type="protein sequence ID" value="ACA88307"/>
        <property type="gene ID" value="Swoo_4051"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4051"/>
    <dbReference type="HOGENOM" id="CLU_2131839_0_0_6"/>
    <dbReference type="OrthoDB" id="2074994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="113" mass="12890" checksum="351DFE96D5E2BF49" modified="2008-04-29" version="1">MSKFTLLKPLEWYMYGQGFILVGWLYVQIVLSPMAILSIASLIFIDIQGEDTSFTILYFASGIGFIAGLVWAERIRRTIGILTFHSFLLSTPEIEGWRDRDGKVISRQKPNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH02</accession>
    <name>B1KH02_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326643.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4058"/>
    <dbReference type="EnsemblBacteria" id="ACA88314">
        <property type="protein sequence ID" value="ACA88314"/>
        <property type="gene ID" value="Swoo_4058"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4058"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_6"/>
    <dbReference type="OMA" id="GKYHACI"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="278" mass="30986" checksum="DA873CAC8DAC11F0" modified="2008-04-29" version="1">MKLRSIHYFQSVYEQGSITAASRQCFVSQPSITAAISQLEQQLNVELFVRHTGGVRPTSAADKLYPLAREMSENEQAILHLFKDSPAPVPLRLGLMRSLGAQRMSDLLTELTQRIDNLELTLVEPDEPSDARVVLSQSASSSEDFIPIWEDKYQLAIPCNWSLASKPIIKIEDLDGLPFINRTPCDVQDRLKHAMTKCGAQFQSRANIRTIEYTWPMVCAGVGAALLPDWQEIKHNKALVLRPIEGEKLIKQIGLAYSASRLSEPAITAVISVCRDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH12</accession>
    <name>B1KH12_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4068</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326653.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4068"/>
    <dbReference type="EnsemblBacteria" id="ACA88324">
        <property type="protein sequence ID" value="ACA88324"/>
        <property type="gene ID" value="Swoo_4068"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4068"/>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_4_6"/>
    <dbReference type="OMA" id="FNQMGRQ"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="69"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="248"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="463" mass="51948" checksum="1925D131383DB8C6" modified="2008-04-29" version="1">MALFSFLSLRTKLILGAVFASQVGTGLSLFVMFKMTQPQTFIAASMFSFVMIFMLAALCAWVISYYATRTLATSLNALEVGLLNFKDNDFSVTIPASGEPQLQSLIELFNESAETLRQERQYIYQRELLLDKVIQSSPNVMLLLDDDQRIIYANDAARHLLNQGNHINGFLLQEVMDKVSDELSSALSKPKGGLFTLSVEGQDEDETWHLSRGQFLLNGQYHHLVLLRQMTHELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRMLTKDLNDPKLKMIFDTIEDRTSHLSQFIFNYARFAKLPLPKKERVDWRKLVDQLGQHYQFTLLGELPSDSGEFDLIQMEQVLLNLLKNAHESGSKIAGVSLSIEASSPLNANNRALDSEGRVMSGTVIEVKDEGSGMPAEVLKQALLPFYSTKQSGTGLGLPLCREIIEAHDGRISLHNRDDMGLCVRVWLPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH75</accession>
    <name>B1KH75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1090"/>
    <dbReference type="EnsemblBacteria" id="ACA85383">
        <property type="protein sequence ID" value="ACA85383"/>
        <property type="gene ID" value="Swoo_1090"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1090"/>
    <dbReference type="eggNOG" id="ENOG5031I6Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2358149_0_0_6"/>
    <dbReference type="OMA" id="PWGTELG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12845" checksum="5FA0B17C2D602A62" modified="2008-04-29" version="1" precursor="true">MILKINQERVTLQARSMAIMNKLIILAFVLLGVFFTLLAGYEGVYIGLFATDEILSEYPWGTELGWPYINKTNYMLYGLFIALLSWLPLLAYVLTKHLPSKDNTTRKDARLL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHE2</accession>
    <name>TSAD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="1">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tsaD</name>
        <name type="synonym">gcp</name>
        <name type="ordered locus">Swoo_1157</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="1">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323796.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHE2"/>
    <dbReference type="SMR" id="B1KHE2"/>
    <dbReference type="STRING" id="392500.Swoo_1157"/>
    <dbReference type="EnsemblBacteria" id="ACA85450">
        <property type="protein sequence ID" value="ACA85450"/>
        <property type="gene ID" value="Swoo_1157"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1157"/>
    <dbReference type="eggNOG" id="COG0533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023208_0_0_6"/>
    <dbReference type="OMA" id="HLEGHIY"/>
    <dbReference type="OrthoDB" id="1257362at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000146023" description="tRNA N6-adenosine threonylcarbamoyltransferase">
        <location>
            <begin position="1"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="134"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <sequence length="337" mass="35869" checksum="D54F9E0380C297B3" modified="2008-04-29" version="1">MRVLGIETSCDETGVAVYDDEQGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLVKQALADANCTLDDIDGVAYTKGPGLVGALLVGACMGRALAYSWDKPAIGVHHMEGHLLAPMLEDDVPAFPFLALLVSGGHSMLVAVEGIGKYEVLGESVDDAAGEAFDKTAKLMGLDYPGGPRLAKLAAKGESGHYRFPRPMTDKPGLNFSFSGLKTFAANTIAAESDDEQTRANIALAFEEAVVDTLSIKCRRALKQTGYKNLVIAGGVSANTRLRSSLAEMMTSLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQTDDLGVKGIPRWPLDTLPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH3</accession>
    <name>B1KHH3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-L-glutamate ligase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325198.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2581"/>
    <dbReference type="EnsemblBacteria" id="ACA86858">
        <property type="protein sequence ID" value="ACA86858"/>
        <property type="gene ID" value="Swoo_2581"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2581"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_865360_0_0_6"/>
    <dbReference type="OMA" id="KRNHSYI"/>
    <dbReference type="OrthoDB" id="937913at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011758">
        <property type="entry name" value="RimK-rel_E_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039523">
        <property type="entry name" value="RimK-rel_E_lig_ATP-grasp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14397">
        <property type="entry name" value="ATPgrasp_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02291">
        <property type="entry name" value="rimK_rel_E_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="46"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="320" mass="35064" checksum="D21054A5CB1DDE81" modified="2008-04-29" version="1" precursor="true">MRFEFAMPSSLHKSGVLGMNKRNIDYIGRYNPRKFYKRVDDKLTTKQLAIANDIAVPALIGVVREQHEIEEIPAMVEGESGFVIKPSKGSGGKGILVITKVEGDRYFKPNGQEVTHSEIYRHVSNILSGLFSLGGAPDVGIVEGLIQFDPVFDGYSYEGVPDIRLIVYKGFPVMGMLRLSTAASDGKANLHQGAVGVGVDIGTGKGLHAVQFDTPVDLHPDTNKKLTDIQVPQWDFLLNTASKAYEMCEMGYLGTDMVLDKVKGPLLLELNARPGLAIQIANGRGILPYLNHVDSLGNHNMTVSKRVEYAKKHFSHNAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHR9</accession>
    <name>B1KHR9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326726.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4141"/>
    <dbReference type="EnsemblBacteria" id="ACA88397">
        <property type="protein sequence ID" value="ACA88397"/>
        <property type="gene ID" value="Swoo_4141"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4141"/>
    <dbReference type="eggNOG" id="COG1315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026157_0_0_6"/>
    <dbReference type="OMA" id="TGHVKFK"/>
    <dbReference type="OrthoDB" id="379544at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005646">
        <property type="entry name" value="FapA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38032">
        <property type="entry name" value="PTHR38032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03961">
        <property type="entry name" value="FapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="556" mass="61300" checksum="2A1EEBB290CA4557" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI07</accession>
    <name>B1KI07_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323831.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1192"/>
    <dbReference type="EnsemblBacteria" id="ACA85485">
        <property type="protein sequence ID" value="ACA85485"/>
        <property type="gene ID" value="Swoo_1192"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1192"/>
    <dbReference type="eggNOG" id="COG3541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084690_0_0_6"/>
    <dbReference type="OMA" id="YHYLNMA"/>
    <dbReference type="OrthoDB" id="974296at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018775">
        <property type="entry name" value="RlaP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34817">
        <property type="entry name" value="PTHR34817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10127">
        <property type="entry name" value="RlaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="259" mass="30669" checksum="0DDCBCC5D78B624B" modified="2008-04-29" version="1">MRTEILENLKTLEIKENIKILYACESGSRAWGFPSADSDYDVRFVYIRNKDWYLRVDYEYCRDVVEKPINDLLDISGWDLKKALKLLRKSNPALIEWFNSPIVYLQNDKFTEAFKELIPILYSPRSCFYHYSHMASGNFREYLQGETVRIKKYFYVLRPILAMQWIEQDRGVVPMEFEVLVDELVHDETLKSAIQKLLEDKRKGFESAYLPRIDVISDFISSELERFKDKAQEQQKSETDFSKLNPFFIDVLNGEYGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI91</accession>
    <name>B1KI91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2666</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325282.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2666"/>
    <dbReference type="EnsemblBacteria" id="ACA86942">
        <property type="protein sequence ID" value="ACA86942"/>
        <property type="gene ID" value="Swoo_2666"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2666"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_378936_0_0_6"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764906" evidence="6">
        <location>
            <begin position="24"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="8">
        <location>
            <begin position="175"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="259"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="731" mass="77235" checksum="90FFB615662B644E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC2</accession>
    <name>B1KIC2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate/glutamate leucyltransferase</fullName>
            <ecNumber evidence="4">2.3.2.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bpt</name>
        <name evidence="7" type="ordered locus">Swoo_2697</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50420"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12669"/>
            <dbReference type="Rhea" id="RHEA-COMP:12674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64720"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133042"/>
            <dbReference type="EC" id="2.3.2.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50412"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12664"/>
            <dbReference type="Rhea" id="RHEA-COMP:12668"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64721"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133041"/>
            <dbReference type="EC" id="2.3.2.29"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the R-transferase family. Bpt subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.29" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2697"/>
    <dbReference type="EnsemblBacteria" id="ACA86973">
        <property type="protein sequence ID" value="ACA86973"/>
        <property type="gene ID" value="Swoo_2697"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2697"/>
    <dbReference type="eggNOG" id="COG2935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077607_0_0_6"/>
    <dbReference type="OMA" id="MVEDSHV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00689">
        <property type="entry name" value="Bpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017138">
        <property type="entry name" value="Asp_Glu_LeuTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="PTHR21367"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037208">
        <property type="entry name" value="ATE_pro_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATE_N" evidence="5">
        <location>
            <begin position="17"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="ATE_C" evidence="6">
        <location>
            <begin position="105"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="27748" checksum="B825CC101B21F101" modified="2008-04-29" version="1">MSFKSHPIAVGVTQAFTCSYLEDELEQLLVLQEETINLELFEQLLALGFRRSGGTIYKPQCPSCNACMPIRIPAKEFMPSRRQKRTLKNNKDIVWKVIDKQQEYHYTLYERYINERHQDGPMYPASREQYEHFINSGWIEPSFIELWHEQRLIGVAVTDVMPNSLSAIYSFFCPNEHKRSLGSLLILIQCRLAKLMDKDFAYLGYQIDESRKMNYKRSYLPYQILTPSGWKQIADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE7</accession>
    <name>B1KIE7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2722</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325335.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2722"/>
    <dbReference type="EnsemblBacteria" id="ACA86998">
        <property type="protein sequence ID" value="ACA86998"/>
        <property type="gene ID" value="Swoo_2722"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2722"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_3_0_6"/>
    <dbReference type="OMA" id="NLCIGEA"/>
    <dbReference type="OrthoDB" id="1087129at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DAO" evidence="4">
        <location>
            <begin position="30"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="429" mass="47461" checksum="E890BC3F23C1103F" modified="2008-04-29" version="1">MPEPRCNSYYNATINDETQYPRLEGEHRVDVVIVGGGFTGVASAVELAERGYKVAIVEANKIGWGATGRNGGQVTGSLSGDQAMTKQLSNRLGCEAEKFVWDLRWRGHEIIKSRVEKYNIECDLKFGHLHTAYKPAHMAEMQATYDEAVKRGMGDEVSLLSKKDIPQYLETPLYHGGLLNKRNMHLHSVNLCIGEARAAEYHGALIFENSPVIDITDGTLPVVTTAHGSITANSVLLAGNAYHKLARKRLAGMLFPASLGNCATVNLTPEIAQAINPHDIAVYDSRFVLDYFRMTADHRLMFGGGTNYSGRDSKDLAKELRPGIERTFPRLKGVEIEFEWTGMAGIVVNRIPQLGKVSKNVFYCQGYSGHGVATSHIMGEIMANAIIGELTEFDLFAGMKHIRLPVGEWLGNQGMALGMLYYRMMENFR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII7</accession>
    <name>MURA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="1">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">murA</name>
        <name type="ordered locus">Swoo_4227</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326810.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KII7"/>
    <dbReference type="SMR" id="B1KII7"/>
    <dbReference type="STRING" id="392500.Swoo_4227"/>
    <dbReference type="EnsemblBacteria" id="ACA88483">
        <property type="protein sequence ID" value="ACA88483"/>
        <property type="gene ID" value="Swoo_4227"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4227"/>
    <dbReference type="eggNOG" id="COG0766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027387_0_0_6"/>
    <dbReference type="OMA" id="CDPHRAT"/>
    <dbReference type="OrthoDB" id="537477at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-0670">Pyruvate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000094724" description="UDP-N-acetylglucosamine 1-carboxyvinyltransferase">
        <location>
            <begin position="1"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="2-(S-cysteinyl)pyruvic acid O-phosphothioketal" evidence="1">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <sequence length="419" mass="44805" checksum="6C62FBAA8EDF85B9" modified="2008-04-29" version="1">MDKLKIEASEALAGNVVISGAKNAALPILMAGVLAETDFVVTNVPNLRDVNTSCELLRCLGAEVTRSDNSEVRISTSSLDHFCAPYDLVKTMRASILILGPLLARFGTADVSLPGGCAIGARPVNLHLHGLEQMGAKIEVEEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAATLADGETIIENAAREPEVIDLANCLIAMGAKIEGAGTDSIRIQGVESLNGCHYRVMPDRIETGSFLIAAAVTRGKIRCVDADPSTLEAVLAKLEDAGATITTGSDWIELDMQGKRPKAVNIKTVPYPGFPTDMQAQFCLLNVLAEGTSTITETIFENRFMHVPELIRMGANMELEGNTCIIQGIERLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRGYEHIEDKFKGLGGQVVRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIJ2</accession>
    <name>B1KIJ2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Intermembrane phospholipid transport system permease protein MlaE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4232</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the MlaE permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326815.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4232"/>
    <dbReference type="EnsemblBacteria" id="ACA88488">
        <property type="protein sequence ID" value="ACA88488"/>
        <property type="gene ID" value="Swoo_4232"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4232"/>
    <dbReference type="eggNOG" id="COG0767">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045686_1_1_6"/>
    <dbReference type="OMA" id="NYLVFPK"/>
    <dbReference type="OrthoDB" id="1253502at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="260" mass="27912" checksum="771E6B911EE143BE" modified="2008-04-29" version="1">MNLLDRVANLGRAAIELVIGFGSAGLMLWGAIARKPRAKGFPLFVKQLYVVGVQSMVLIFVSGLFIGMVLALQGYNILVGFGTEESLGPMVALSLLRELGPVVTALLFAGRAGSALTAEIGLMKSTEQLSSLEMMAIDPLRQIIAPRFWAGVVSLPLLALIFTAVGIYGGHIVGVEWKGIDSGSFWSILQASVEWRQDIVNCLIKSLVFAVVVTWIALYRGYQVIPNPEGISKATTQTVVQSSLAVLALDFLLTALMFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP1</accession>
    <name>B1KIP1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326864.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4281"/>
    <dbReference type="EnsemblBacteria" id="ACA88537">
        <property type="protein sequence ID" value="ACA88537"/>
        <property type="gene ID" value="Swoo_4281"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4281"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068019_0_0_6"/>
    <dbReference type="OMA" id="YFPSAVW"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="39"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="310" mass="35051" checksum="27DBE4F604E1DB3E" modified="2008-04-29" version="1" precursor="true">MRFFAQSKLITKYLLMIFLIGSSGQLLARDLDEIKAEGVLRHIGVPYANFVAKYTEGNKVTHSGLDIELMQNFAKYLGVDYQFIPATWTTVFGKLTGVNGQFVDNKVVYSSPQLIEGDVMAHGVTILDWRKEIIDFSDDYFPSAVWLIARTSSDLIPIKPSGSLTEDIIAVKSLIKGRDVLAMKQSCLDPDLYDLYLTQANVILPTKQLQLNEMVPAMLNDEAETTLLDVADSLIALEKWPSEIKVIGPISEEQRMAMGFRKDSPKLRKAFNQYLKQIRADGSFNELVKKYYPSAFHYYNNYFSQAITSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIT7</accession>
    <name>B1KIT7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323931.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1293"/>
    <dbReference type="EnsemblBacteria" id="ACA85585">
        <property type="protein sequence ID" value="ACA85585"/>
        <property type="gene ID" value="Swoo_1293"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1293"/>
    <dbReference type="eggNOG" id="COG1047">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098197_3_0_6"/>
    <dbReference type="OMA" id="FGQTEDH"/>
    <dbReference type="OrthoDB" id="2044224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="14747" checksum="FE6F6C1D81A743FB" modified="2008-04-29" version="1">MSDTRSIVCHMNIVLEDGSTADSTKASGKPARLNIGDDSLSPAFEAEITNLAQGDKHSFTLQAVDAFGESNPDAIHHMDRSKFPADMSLEPGVIVSFGGPGGSEIPGMIREVAGDSITVDLNHPLAGQVVTFELEVVQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV6</accession>
    <name>B1KIV6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase BadF/BadG/BcrA/BcrD type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323950.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1312"/>
    <dbReference type="EnsemblBacteria" id="ACA85604">
        <property type="protein sequence ID" value="ACA85604"/>
        <property type="gene ID" value="Swoo_1312"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1312"/>
    <dbReference type="eggNOG" id="COG2971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016274_2_0_6"/>
    <dbReference type="OMA" id="PANIMRD"/>
    <dbReference type="OrthoDB" id="1589192at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BcrAD_BadFG" evidence="1">
        <location>
            <begin position="13"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="300" mass="31457" checksum="5870DB91340D29E4" modified="2008-04-29" version="1">MIVNQTKENPLFIGIDGGGSKCRATIYSAEDGVIGTGVAGRANPLHGLSQTFESIQLSTELALKDAGMAIGDSKGLVAGLGLAGVNVPRLYQDIVNWEHPFADMYVTSDLHTACIGAHKGGEGAVIITGTGSCGYANVDGKFISLGGHGFALGDKGSGAWLGLKAAEQSLLHLDGFAEKTILTEKLLNHFKVNDALGIVENLAGKSSSVYAKLARIVLECANQQDEVAQAIVKEGAAYISELARKLFEINPPRFSMIGGLAEPLAPWLDKDVVTKLSPTLAPPELGATYFARQQFGCKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIW7</accession>
    <name>B1KIW7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323961.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1323"/>
    <dbReference type="EnsemblBacteria" id="ACA85615">
        <property type="protein sequence ID" value="ACA85615"/>
        <property type="gene ID" value="Swoo_1323"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1323"/>
    <dbReference type="eggNOG" id="ENOG502Z7W2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087938_0_0_6"/>
    <dbReference type="OMA" id="AYQNGDK"/>
    <dbReference type="OrthoDB" id="1570370at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021307">
        <property type="entry name" value="DUF2884"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11101">
        <property type="entry name" value="DUF2884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766675" evidence="1">
        <location>
            <begin position="25"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="276" mass="30590" checksum="04D31AF689AD0B16" modified="2008-04-29" version="1" precursor="true">MRKLATLLGITAAIFATTMTSVQAHEDHKSNSYSDHNSECEVTLNYDVAVEPKKLTVTEGSAEVYRIEMDQLFVEGKPVSLNRSQKKLLTQYSDEVSTQVPEVIGLVHDAVGIASSAASMALTPLLGDAAGAKLDEMMDGLEERIEKVAYQNGDKFYLGATHSSLEDTFGEEFEQELEQLVKNSIGSMMVNIGSQMLAGDGESFEQSMEAFATKMENVGQDIELQMESQAQSLEDRADKMCERFRYLVELEQKLRAEVPELAKYPLIDAPQKELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ26</accession>
    <name>B1KJ26_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chalcone_isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2770"/>
    <dbReference type="EnsemblBacteria" id="ACA87046">
        <property type="protein sequence ID" value="ACA87046"/>
        <property type="gene ID" value="Swoo_2770"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2770"/>
    <dbReference type="eggNOG" id="COG3572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102167_1_1_6"/>
    <dbReference type="OMA" id="ATRDQWQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16036">
        <property type="entry name" value="Chalcone_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="SSF54626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767118" description="Chalcone_isomerase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone_isomerase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="19470" checksum="DFBA4170C359C609" modified="2008-04-29" version="1" precursor="true">MKILYLVLSIFSLSVSASPFPQLIKSGEGEMDYLFWTIYRAELYVESLPYQEESFPKALKIEYYRDIDSDDLIDATKDQWLHLGINQALINQWTAELPTIWPDISKGDELIIYVSKDGESTFYSGQEGQTVKRLGQVDDNQFGRAFLDIWLSEKTTKPKLRAKLMGNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ82</accession>
    <name>B1KJ82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325438.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87102">
        <property type="protein sequence ID" value="ACA87102"/>
        <property type="gene ID" value="Swoo_2827"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2827"/>
    <dbReference type="eggNOG" id="ENOG50301FE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056090_1_0_6"/>
    <dbReference type="OMA" id="CYHGNYF"/>
    <dbReference type="OrthoDB" id="1754907at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006672">
        <property type="term" value="P:ceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="270" mass="31186" checksum="866BDA69E63A0B24" modified="2008-04-29" version="1">MNRLNQNNLVVMGCFNWRHALLLAIVFVPLLWIFSLEPIPQPSVYHEFADQRDLIYLPNFMNVLSNIPFLIIGVLGLYQTMSIYQWRVLNGWTLLFIGILLVFAGSSYYHWSPSNNSLVWDRLPMTFGFMGLFVALIGEYVSSKLSEMILLPALFIGILSVSYWHWTDDLRFYYWVQLVPLLTLPIILLLFPRIYSHHKLLFLAFACYVLAKIAEVYDLNIFLATGELISGHTVKHLLAASGCYFILCMLRNRVVIARASRGKSQRKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJC5</accession>
    <name>B1KJC5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326923.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4344"/>
    <dbReference type="EnsemblBacteria" id="ACA88597">
        <property type="protein sequence ID" value="ACA88597"/>
        <property type="gene ID" value="Swoo_4344"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4344"/>
    <dbReference type="eggNOG" id="ENOG5032Y6W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161186_0_0_6"/>
    <dbReference type="OMA" id="HTRVIEQ"/>
    <dbReference type="OrthoDB" id="1871546at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="103" mass="11792" checksum="172AFFFB1D61F539" modified="2008-04-29" version="1">MPHTRVLEQLKENLQTAYRKSIDADGKLDELKKAGHAKFNTIFTQDEGFSTRSNRFKPYVEELASELEKMPTDPELLPAALEQFVRKLGVLLQTLQAFKDQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJF1</accession>
    <name>B1KJF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326949.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4370"/>
    <dbReference type="EnsemblBacteria" id="ACA88623">
        <property type="protein sequence ID" value="ACA88623"/>
        <property type="gene ID" value="Swoo_4370"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4370"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_330061_0_0_6"/>
    <dbReference type="OMA" id="TATHFAY"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766707" evidence="1">
        <location>
            <begin position="30"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="869" mass="97635" checksum="43775A4C4A2008CB" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG5</accession>
    <name>B1KJG5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4385</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326963.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4385"/>
    <dbReference type="EnsemblBacteria" id="ACA88637">
        <property type="protein sequence ID" value="ACA88637"/>
        <property type="gene ID" value="Swoo_4385"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4385"/>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030140_0_2_6"/>
    <dbReference type="OMA" id="ATGVHRK"/>
    <dbReference type="OrthoDB" id="944149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="210"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="336" mass="36664" checksum="E045AD83461A5CA9" modified="2008-04-29" version="1">MSIKIGINGFGRMGRLALRAAWDWDDVEFVQINDPAGDAKTLAHLLTFDSVHGRWQHEAVNDGSDIVIGDKRIATTANKAIADTDWSGCDLVIEASGVMKTKALLQAYLEQGVKRVVVTAPVKEKGVLNIVMGVNHQYYDKALHPIVTAASCTTNCLAPVVKVLHEKIGIKHGSMTTIHDITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRIPLANASITDCVFELEKVTTEAEVNALLKEAAEGELKDILGYEERPLVSVDYKTDPRSSIIDAPSTMVVNGTQVKLYVWYDNEWGYANRTAELARMVGRLDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ9</accession>
    <name>B1KJQ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324078.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1440"/>
    <dbReference type="EnsemblBacteria" id="ACA85732">
        <property type="protein sequence ID" value="ACA85732"/>
        <property type="gene ID" value="Swoo_1440"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1440"/>
    <dbReference type="eggNOG" id="ENOG5033ANC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148741_0_0_6"/>
    <dbReference type="OMA" id="YQMIELC"/>
    <dbReference type="OrthoDB" id="1947521at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045441">
        <property type="entry name" value="DUF6506"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20116">
        <property type="entry name" value="DUF6506"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="10894" checksum="F58098235CB48C38" modified="2008-04-29" version="1">MTLTNYGFIVLAKEYQPTQNRSVIENEYFKTQVVGVSTVEQAITVCRELIEEGVQVIELCGGFGEESANKVINSLDSQTPIGFVGFSVSETQKLTKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR9</accession>
    <name>B1KJR9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Universal stress protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85742">
        <property type="protein sequence ID" value="ACA85742"/>
        <property type="gene ID" value="Swoo_1452"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1452"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_18_0_6"/>
    <dbReference type="OMA" id="CGNHNQS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006276">
        <property type="entry name" value="UspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="3">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16804" checksum="E57637B41E1C510A" modified="2008-04-29" version="1">MNYKHILLSVALNKDSEKILRKAAQIAKQNNAQLSLIHVDLDIPHTYEGMLGIEFQERDQALRQESIAAMNQLANSQEYEIKEHIFHSGYVDDEIIDSVEKYHIDLLIMGHHKSSFIRQMLLSPSEPVLRNMPCDLMFIKLDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJU2</accession>
    <name>B1KJU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2854"/>
    <dbReference type="EnsemblBacteria" id="ACA87129">
        <property type="protein sequence ID" value="ACA87129"/>
        <property type="gene ID" value="Swoo_2854"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2854"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029191_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767134" evidence="2">
        <location>
            <begin position="24"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="572"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="654" mass="74206" checksum="2306A46DC5CF5CEF" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJV2</accession>
    <name>B1KJV2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NADH-quinone oxidoreductase subunit F</fullName>
            <ecNumber evidence="13">7.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_2864</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2864"/>
    <dbReference type="EnsemblBacteria" id="ACA87139">
        <property type="protein sequence ID" value="ACA87139"/>
        <property type="gene ID" value="Swoo_2864"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2864"/>
    <dbReference type="eggNOG" id="COG1894">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014881_0_1_6"/>
    <dbReference type="OMA" id="CDDVIMD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 13" id="KW-0288">FMN</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 13" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-0874">Quinone</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="NADH_4Fe-4S" evidence="14">
        <location>
            <begin position="333"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA87139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="50311" checksum="EF6E7DF619413134" modified="2008-04-29" version="1">MNQTLPHNPLTRFITDNENCWSIEQYQNHGGYQGFRKSLTQSQEQLLDTLKESNLRGRGGAGFPTGLKWSFVPRGDDAPSPRYLIVNADEMEPGTFKDRMLMEKTPHQIIEGLLIGAQTLGASIGYVFLRGDYYLAEERMTKALQECRDANLLGKNILGSGLDFDIHLHTSAGRYICGEETALINSMEGKRANPRAKPPFPQVAGLWGKPTIVNNVETFCNLPHIINFGPIWFKELGLNDDAGTKIFGVSGRVKRPGLWELPMGTPIREIIEQHAGGMCDGYTLKGFLPGGGSTDFLVTEHLDIPMDYDTIGKQGSRMGTGTIIILDDRYCPVAMVLNLIKFFAQESCGWCTPCRDGLPWAQVLLEKIERGEGEPEDITQLEELCRFAAPGNTFCALAPGAVEPLQSALKYFREDFEAHISQACCPFHDKKRQGIDEIGTPCIKGSGGDKYEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ5</accession>
    <name>B1KJZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome segregation and condensation protein ScpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325518.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2909"/>
    <dbReference type="EnsemblBacteria" id="ACA87182">
        <property type="protein sequence ID" value="ACA87182"/>
        <property type="gene ID" value="Swoo_2909"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2909"/>
    <dbReference type="eggNOG" id="COG1354">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038686_0_1_6"/>
    <dbReference type="OMA" id="YLVMAAM"/>
    <dbReference type="OrthoDB" id="959677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01805">
        <property type="entry name" value="ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="29621" checksum="310E85C868095510" modified="2008-04-29" version="1">MQGTQKSLPLAIVRGEPVKNFPADLFIPPEALEVFLESFEGPLDLLLYLIRKQKLDVVELPIWPVTEQYLEYIELLQGARVELAADYLVMAATLAEIKSRLLLPRPKSEVEDEEDPRAQLIRQLKAYEVIKLAQQELDSLPRLERDIFQAKAAPAPDIKPVLLPPSVSLADMARAFASVLQRVEATEDHHVKREVLSTRERMTQILALLDGEDYLPFEALFDVKEGRSGVVVSFLALMELVKELLVELIQAEPFSTIHVKAY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK51</accession>
    <name>HSLU_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent protease ATPase subunit HslU</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Unfoldase HslU</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hslU</name>
        <name type="ordered locus">Swoo_4430</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327008.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KK51"/>
    <dbReference type="SMR" id="B1KK51"/>
    <dbReference type="STRING" id="392500.Swoo_4430"/>
    <dbReference type="EnsemblBacteria" id="ACA88682">
        <property type="protein sequence ID" value="ACA88682"/>
        <property type="gene ID" value="Swoo_4430"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4430"/>
    <dbReference type="eggNOG" id="COG1220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033123_0_0_6"/>
    <dbReference type="OMA" id="KYGMIKT"/>
    <dbReference type="OrthoDB" id="718259at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00249">
        <property type="entry name" value="HslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="PTHR48102:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_1000100976" description="ATP-dependent protease ATPase subunit HslU">
        <location>
            <begin position="1"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00249"/>
        </source>
    </evidence>
    <sequence length="441" mass="49840" checksum="203ED9CCFB427FDC" modified="2008-04-29" version="1">MSEMTPREIVHELDSHIIGQHNAKRSVAIALRNRWRRMQLDADFRQEVTPKNILMIGPTGVGKTEIARRLAKLARAPFIKVEATKFTEVGYVGKEVEQIIRDLTDSAIKLTREEQMKKCKFRAEEAAEERILDALLPKAKEDWDNEKPDDSATRQVFRKKLREGQLDDKEIEIDVSAPQVGIEIMSPPGMEEMTNQLQSMFQNMGLGASKRRKMPIKEAYKLMVEEEAAKLVNQDDLKEQAIELVEQHGIVFLDEIDKICKRGEASGPDVSREGVQRDLLPLVEGCTVNTKHGMVKTDHILFIASGAFQMSKPSDLIPELQGRLPIRVELDALSADDFKRILTEPHASLTEQQIALMGTEGVKIEFTEDGIESIAQAAWQVNERTENIGARRLHTVMEKLTEELSYEASDKSGSTIVIDAKYVSDHLDNLVQDEDLSRFIL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK65</accession>
    <name>UBID_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-octaprenyl-4-hydroxybenzoate carboxy-lyase</fullName>
            <ecNumber evidence="1">4.1.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Polyprenyl p-hydroxybenzoate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiD</name>
        <name type="ordered locus">Swoo_4444</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-hydroxy-3-all-trans-polyprenylbenzoate + H(+) = a 2-all-trans-polyprenylphenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:41680"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9516"/>
            <dbReference type="ChEBI" id="CHEBI:1269"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="4.1.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </cofactor>
        <text evidence="1">Binds 1 prenylated FMN (prenyl-FMN) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiD family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.98" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327022.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KK65"/>
    <dbReference type="SMR" id="B1KK65"/>
    <dbReference type="STRING" id="392500.Swoo_4444"/>
    <dbReference type="EnsemblBacteria" id="ACA88696">
        <property type="protein sequence ID" value="ACA88696"/>
        <property type="gene ID" value="Swoo_4444"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4444"/>
    <dbReference type="eggNOG" id="COG0043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023348_4_1_6"/>
    <dbReference type="OMA" id="SYQQFWG"/>
    <dbReference type="OrthoDB" id="1012819at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008694">
        <property type="term" value="F:3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01636">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023677">
        <property type="entry name" value="UbiD_bacteria"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00148">
        <property type="entry name" value="TIGR00148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0210">Decarboxylase</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0288">FMN</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="chain" id="PRO_1000186724" description="3-octaprenyl-4-hydroxybenzoate carboxy-lyase">
        <location>
            <begin position="1"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="175"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="189"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="194"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01636"/>
        </source>
    </evidence>
    <sequence length="493" mass="55514" checksum="5E9CDC38A571EB2B" modified="2008-04-29" version="1">MSFKDLRSFIDHLESQGELKRISHPVDPNLEMTEIADRVLRAKGPALLFENPVGNDMPVLANLFGTPKRVAMALGKEDPLALREVGELLAFLKEPEPPRGFKDAIAKIPMFKQALNMPPKTVRNPPCQQVVKTGEEVDLTKLPIQHCWPGDVAPLVTWGLTITKGPRQKRQNLGIYRQQLLGRDKLIMRWLDHRGGALDFKDFKEKHPGERYPVVVALGSDPVTILGAVTPVPDSMSEYAFAGLLRGERTDVCKAISCDLEVPATSEIILEGYIDPDEMAEEGPYGDHTGYYNETDSFPVFTVTHITHRKDAIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIIDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIVVVDEDVNCRDWNDVIWAITTRMDPKRDTVMIENTPIDYLDFASPVAGLGSKMGMDATNKWEGETDREWGTPIVMDQAVKDKVDQIWADLGIDDAPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG5</accession>
    <name>B1KKG5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1517</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1517"/>
    <dbReference type="EnsemblBacteria" id="ACA85805">
        <property type="protein sequence ID" value="ACA85805"/>
        <property type="gene ID" value="Swoo_1517"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1517"/>
    <dbReference type="eggNOG" id="COG2259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058421_8_1_6"/>
    <dbReference type="OMA" id="HEMQNFI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="138" mass="15184" checksum="C19AC5463C189C11" modified="2008-04-29" version="1">MRVDDMKDKIALNAALLTSGRVLLALYFLLPGIMKFVSWEMHITLMAKHNMVMIPQLLAIAGVFQISAAIALILNRYTFIVSLMLAGLVLVINVSLHDFWNYGGVEAAHEMQNFIKNLGIFAGLLVLAGHSRCAAQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV0</accession>
    <name>B1KKV0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327082.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4505"/>
    <dbReference type="EnsemblBacteria" id="ACA88756">
        <property type="protein sequence ID" value="ACA88756"/>
        <property type="gene ID" value="Swoo_4505"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4505"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_2_2_6"/>
    <dbReference type="OMA" id="TQIRAEM"/>
    <dbReference type="OrthoDB" id="1213601at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="28"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="310" mass="34452" checksum="09D0E7F2B30AFDD5" modified="2008-04-29" version="1">MIAGIDTDLIVLGIWGLIFAIFVIKLFQSIRLVPTKSAYIVERLGKYHSTLDAGFHALIPFVDKVAYIHDLKEETIDVPPQECFSSDEVNVEVDGVIYISVMDPVKASYGVVDYRYAAIQLAQTTTRSVIGTLDLDRTFEERDVISAKVVEVLDQAGAMWGIRVHRYEIKNITPPETVKNAMEMQVNAERERRALLAKSEGDKQSKINRSEGIKAEMINISEGEMQKRINEAEGKGEEIITIARATADSIERMAAVIAAPGGKNVVRMQLGAEYLKQFDGLSSNGSKVVLPGNLMDFEHWMDSIGLEETK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKX2</accession>
    <name>LPXC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <shortName evidence="1">UDP-3-O-acyl-GlcNAc deacetylase</shortName>
            <ecNumber evidence="1">3.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lpxC</name>
        <name type="ordered locus">Swoo_4528</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LpxC family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327104.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKX2"/>
    <dbReference type="SMR" id="B1KKX2"/>
    <dbReference type="STRING" id="392500.Swoo_4528"/>
    <dbReference type="EnsemblBacteria" id="ACA88778">
        <property type="protein sequence ID" value="ACA88778"/>
        <property type="gene ID" value="Swoo_4528"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4528"/>
    <dbReference type="eggNOG" id="COG0774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046528_1_0_6"/>
    <dbReference type="OMA" id="IVFYRSD"/>
    <dbReference type="OrthoDB" id="428602at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000122822" description="UDP-3-O-acyl-N-acetylglucosamine deacetylase">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00388"/>
        </source>
    </evidence>
    <sequence length="305" mass="33648" checksum="BBADE7206D0B1C69" modified="2008-04-29" version="1">MIFQRTVKEMVKTTGVGLHSGNKVTLSIKPAPVNYGIVLVRTDLEPAVSIPAKADQVRETTMCTALVNDDGVRISTIEHLFAALAGLGIDNALIEVDAPEIPIMDGSASPWVFLLQSVGIQEQSAAKKYLRIKDTIRVEDGDKWAELKPFNGFRVDFAIDFNHPEIARSQQHMVMDFSTSAFVRDISRARTFGFMRDIEYLRANNLALGGSMENAVVLDEYKVLNPDGLRYEDEFVKHKILDAFGDLYVAGHAIVGEFCAFKTGHALNNQLVRALLAQQDAWELVSFEKDEAPVSFSVPAGAVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLL9</accession>
    <name>B1KLL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325652.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87316">
        <property type="protein sequence ID" value="ACA87316"/>
        <property type="gene ID" value="Swoo_3045"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3045"/>
    <dbReference type="eggNOG" id="ENOG5032U2W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080163_0_0_6"/>
    <dbReference type="OMA" id="HYAFANY"/>
    <dbReference type="OrthoDB" id="914252at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767465" evidence="1">
        <location>
            <begin position="23"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="272" mass="30776" checksum="954E0890735405F1" modified="2008-04-29" version="1" precursor="true">MVLNKSLFICLSLLFLSSSIQAEEDFTHYAFANYLGSGLYRTSGQNTTVVNMPMSFELWQDDTDSLTLRTPVSLGFFNFKWDDLPEGELPSSVGTFTFTPGVEYRTRTAENHEFQAYFDLGYGKNLNSGDHVAIISGGVSSLLELEYKQSAPVWVNRLYFAGYQSFDGSQAETYSAIQSGFDIGTDIHWRWDWLGVDVEPRVFAVGYWYFDKLRFATPFGDDVLVSHSLEVGATLAFSKPILWEWMGIDRLGLSVRAGDGVQVWRLIFEFPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLN2</accession>
    <name>B1KLN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3058</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325665.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3058"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87329">
        <property type="protein sequence ID" value="ACA87329"/>
        <property type="gene ID" value="Swoo_3058"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3058"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_1_6"/>
    <dbReference type="OMA" id="YFVAPYD"/>
    <dbReference type="OrthoDB" id="949956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765027" evidence="3">
        <location>
            <begin position="27"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="Fn3_like" evidence="4">
        <location>
            <begin position="774"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="857" mass="95086" checksum="C72FA09332B22765" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM16</accession>
    <name>B1KM16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium:dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4646</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327220.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4646"/>
    <dbReference type="EnsemblBacteria" id="ACA88896">
        <property type="protein sequence ID" value="ACA88896"/>
        <property type="gene ID" value="Swoo_4646"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4646"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_2_6"/>
    <dbReference type="OMA" id="YFAYQVG"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="405" mass="42842" checksum="56829E1E49764ADC" modified="2008-04-29" version="1" precursor="true">MWHSIRAYQTSIILLLALMLGGALGLTLPEVALKLKPIGQIFLNLLFMIIVPLVAISVTSSIARMTDLKRLGVILVAVMLVSITMAIVPAVGILGLAMAFDPAQGVTLDLTQEIQTGQGSMDFVSLLTTNDFVGLLSKSNILALIIMSVISGIAIGQSGEDGKRISSMLDSLNTVIMKIVSILMYGAPIGLGAYFASTMASQDPEIITTFAHTIGLFFIASFIYLTLGSSLYAWLGGGAKGVHQFWRNAIEPAATALGTSSSLASLPVNIRAANKMGIKEEIADICLPLLVNLNKGGASMITALKIIFIYSLLGLEFTHEVFAITVLISVLSAFVIGGVPGGAFLGEIFIVTTLGLPLETIPILVIIGAVTDAPSTVINVVHDLNATQIIERFTQRESKDQEVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM92</accession>
    <name>B1KM92_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoH</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase sigma-32 factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoH</name>
        <name evidence="9" type="ordered locus">Swoo_0204</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the RNA polymerase core enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322854.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0204"/>
    <dbReference type="EnsemblBacteria" id="ACA84505">
        <property type="protein sequence ID" value="ACA84505"/>
        <property type="gene ID" value="Swoo_0204"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0204"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_5_6"/>
    <dbReference type="OMA" id="YQRWLAE"/>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00961">
        <property type="entry name" value="Sigma70_RpoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012759">
        <property type="entry name" value="RNA_pol_sigma_RpoH_proteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02392">
        <property type="entry name" value="rpoH_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2 6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="54"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="78"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="283" mass="32010" checksum="134D9D0B78B8EC30" modified="2008-04-29" version="1">MTNQSMALTVPHGSGSLEAYVHSAHNISMLEPEQEYELAKRLQETGDLQAAKQLIMSHLRFVVHVAKGYSGYGLPQADLIQEGNIGLMKAVKRFDPDVGVRLVSFAVHWIKAEIHEYVLKNWRIVKVATTKAQRKLFFNLRKSKKRLGWFSDEEVGMVADNLGVSKADVTEMESRMAAQDPAFDLASDNDDDQDFSPVHYLEDHSSDLASQVENDNLESNNQARLLSAIKTLDERSQHILQARWLNEDKTTLQELAATYQVSAERIRQLEKNAMNKLKGRMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG0</accession>
    <name>B1KMG0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable alginate O-acetylase</fullName>
            <ecNumber evidence="11">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_1673</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; alginate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1673"/>
    <dbReference type="EnsemblBacteria" id="ACA85958">
        <property type="protein sequence ID" value="ACA85958"/>
        <property type="gene ID" value="Swoo_1673"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1673"/>
    <dbReference type="eggNOG" id="COG1696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025255_0_1_6"/>
    <dbReference type="OMA" id="FLTGFWH"/>
    <dbReference type="UniPathway" id="UPA00286"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024194">
        <property type="entry name" value="Ac/AlaTfrase_AlgI/DltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028362">
        <property type="entry name" value="AlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500217">
        <property type="entry name" value="AlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016636">
        <property type="entry name" value="AlgI_DltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0016">Alginate biosynthesis</keyword>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="410" mass="48081" checksum="33D3F27EA6D55B73" modified="2008-04-29" version="1">MGEKESKSARKPYLWLSLMVNLGILFVFKYWNFFGYSLSSLLSVNLELHNLLLPLGLSFYTLQTLSYIFDVYLGKIKPERHLGLFCLYVSFFPQLVAGPIERSRTLLPQLKSLELPTLYQFRYGLLLIVWGFFIKLVIADNLSASINSVYFGKEYFPFWVYWFIGALVTLKIYCDFMAYSEIARGVGMLFGVKLTLNFRRPLFATNLRSFWQRWHISLTRWIGDYIQIPLLRRYPTQPHRSVVTIMTLVIIGFWHSASWNFILFGLFHGMVMVIWSPIAKNISILFEGSFAFSSIFGRFFLAIVLMSSAPMFYIQDTSILFNILKNMLLFDLFEPTQISSIHGKVMLIKALFGFILLFLYSFFNEFKQQDFIVNLARSSSNRRWCEMLFIVFSTLFLGSFVHEPFIYFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH5</accession>
    <name>B1KMH5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TrkA-C domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1688</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324319.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1688"/>
    <dbReference type="EnsemblBacteria" id="ACA85973">
        <property type="protein sequence ID" value="ACA85973"/>
        <property type="gene ID" value="Swoo_1688"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1688"/>
    <dbReference type="eggNOG" id="COG0471">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005170_6_2_6"/>
    <dbReference type="OMA" id="RCIDADE"/>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="195"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="282"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="575" mass="62341" checksum="83DF37C0619B19A2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI6</accession>
    <name>B1KMI6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324330.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1699"/>
    <dbReference type="EnsemblBacteria" id="ACA85984">
        <property type="protein sequence ID" value="ACA85984"/>
        <property type="gene ID" value="Swoo_1699"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1699"/>
    <dbReference type="eggNOG" id="COG1596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054170_0_0_6"/>
    <dbReference type="OMA" id="DGIACYD"/>
    <dbReference type="OrthoDB" id="687725at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766846" evidence="2">
        <location>
            <begin position="25"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="420" mass="45420" checksum="43840BA31692A8EA" modified="2008-04-29" version="1" precursor="true">MKTTRLLFLKALLVVGVISLSACITPNMSHRDNVCQSDKKKQKLNQMSSKQKEKTCHYYGNKTPYMRGYIAEVASKDTPATKTITSASDYASFTKLFNTPLLSVGDRVSIKILNGDEFSAKVEVNADGFIYLPYLPALKAHGVSIPSLKKNIKQLLVDENLMLEGAIRLSITPLRWAPIQVSVSGAVFEPGLHSINRKSDTEIKDDDGGHSGDQAAGRSIYMALKASGGISPNADISRIVITRGRHIIEVDLTGVINGDPVPRLTLMAEDHIHVPQNTHFDDSLARPSQITAPGIRVFISNLTQPASSNAQSAVDTEATRFPYGTRLLTGVIGGNCVGGAQSTNASRHVVLVTKNPITQEVDVVERSVDVLMSQSWKSHINPVLLPGDGIACYDSGVTNIREIARTITEIIVPATLLGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMK9</accession>
    <name>B1KMK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Two component, sigma54 specific, transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1722</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324353.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1722"/>
    <dbReference type="EnsemblBacteria" id="ACA86007">
        <property type="protein sequence ID" value="ACA86007"/>
        <property type="gene ID" value="Swoo_1722"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1722"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_5_6"/>
    <dbReference type="OMA" id="CATHQNL"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="150"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="51076" checksum="E1786652167935B9" modified="2008-04-29" version="1">MSPESLEQYRVIIVDDEPLIGSALVQLFELEGISAFATSEPKSIIERIDINWPGVLISDVNMPELNGISLMQSLIKQDNDLPIILLTGFGDIAMAVNALKQGAYDFLEKPFNNEYMLDVVKRALEKRALTLENRKLKQELESISFPGPRILGHSPGIKQMKHILHQVLDMPADVLIEGETGTGKELVARYLHDHSVRNQANFVAINCGAIPETIIESELFGAEAGAFTGADKTRIGKFEYANGGTLFLDEIESTPLSLQVKLLRVLEDRCVERLGSNKTVPLDIRIIAATKVDLDSLCKTGEFRQDLLYRLNLVTVSIPALRERREDIGLLFLHFARIASSRYHKALIPLTSEQGAQLTSHDWPGNVRELRNLAERYVLLGAEAAFATSINNPVNLNGAMSLQQRVEFFERLLIEEALSHNKGSIKLTMEQLELPRKTLYDKMQKYDLDRKLFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ2</accession>
    <name>B1KMQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325766.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3159"/>
    <dbReference type="EnsemblBacteria" id="ACA87430">
        <property type="protein sequence ID" value="ACA87430"/>
        <property type="gene ID" value="Swoo_3159"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3159"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_4_2_6"/>
    <dbReference type="OMA" id="VITHQTS"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiolase_N" evidence="1">
        <location>
            <begin position="67"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="2">
        <location>
            <begin position="260"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="349" mass="38044" checksum="E87297B04224CE3A" modified="2008-04-29" version="1">MKYSQVFINSLAYELAPEVVSTSDLESRLAPLYKKFRIPMGQLAALTGIQERRWWPKGHRLSDGALSAAHKAIDETGIQVSDLGAVVYTGVCRDQHEPATACRIAAELGVSKDTAIYDISNACLGVLSGILDIANRIELGQIKAGLVVSCESARHIVDITIDNMLAEPTMQNYAKSLATLTGGSGAVAVLLTDGSLPLKSDRQHQLLGASHLSAPEHHNLCQWGLQEAGVHLYREFMRTDGVALLKEGVELARHTWSHFLEQRDWVVEQVDKVICHQVGASNRRQVLNALNIPQEKEFPTYQLLGNMGTVSLPVTAALAHDQGFLQKGDQVSFLGIGSGLNCMMLGIKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMR6</accession>
    <name>B1KMR6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tail Collar domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325780.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3173"/>
    <dbReference type="EnsemblBacteria" id="ACA87444">
        <property type="protein sequence ID" value="ACA87444"/>
        <property type="gene ID" value="Swoo_3173"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3173"/>
    <dbReference type="eggNOG" id="COG4675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087872_0_0_6"/>
    <dbReference type="OMA" id="MFAGNFP"/>
    <dbReference type="OrthoDB" id="1837650at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="2">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="18916" checksum="2668AE97A150A704" modified="2008-04-29" version="1">MSEPFIGEIKMVGFNFAPRSYAKCDGALLPISQNTAMFSLLGTEFGGDGRTTFGLPDLRGRTPMHQGNGPGLSPKTMGQSSGSESNTLQLNQMPKHTHSAQLDAVSTEGTSAVPDNNMYLAKSSSGLTSVNSYSNGTPDTVISPHETNTAGGNSAINNMQPYQVVNFIIAIQGLFPSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN13</accession>
    <name>B1KN13_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327288.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4720"/>
    <dbReference type="EnsemblBacteria" id="ACA88970">
        <property type="protein sequence ID" value="ACA88970"/>
        <property type="gene ID" value="Swoo_4720"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4720"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060318_1_0_6"/>
    <dbReference type="OMA" id="SKWEGAQ"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="327" mass="36852" checksum="591658140879AF63" modified="2008-04-29" version="1">MILAEKIIRLRKQLGWSQEELAEKMAISRQSVSKWESANSIPDLNKIIKLADIFEVSTDFLLKDEYEANSYNDEPKPSNLNQVSLEQATQYVNSKIQEAALITKGVILSVCSAIPLFFFLAMAETQRMGITDDAATTIGLVCVLMLVATAVSFFIKTNQFKNETAAIENQDFELAYGVHSIFSERLAAYQPRYNRSLFIAISLFIFSFVPLIVVNQFFDTSGMVLMMIAVLLLMVSAGLFFIIPASTKLDAYNHILQDKGADTEQTKRNKRAEKLAAFYWPLLIAIFLGWSLWTMDWGTTWIIWPVGAILFAALVGLMELLEKPQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN54</accession>
    <name>B1KN54_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322900.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0250"/>
    <dbReference type="EnsemblBacteria" id="ACA84551">
        <property type="protein sequence ID" value="ACA84551"/>
        <property type="gene ID" value="Swoo_0250"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0250"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053994_0_0_6"/>
    <dbReference type="OMA" id="PGHHTEH"/>
    <dbReference type="OrthoDB" id="654185at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="419" mass="48217" checksum="7BA68DD95CD0655B" modified="2008-04-29" version="1">MVVMAEKEGIVNRTPDNQQLDDIAKDYVKLVLAVGLHDASYVDAYYGPESWREKCQLQPLRSLKRDVAALLGRLGALKLTGGDRRLLERQEFLGKQLASVEYYINHLLGSESCFATESTGLYDTQAEIFSPESFQPALDDIDCLLPGSGELTGRFDAYRAQFIVPEHQIPKVFSAAVEKSRELTSTYIDLPENESFRIEFVNDKVWSAYNWYQGDYQSLIQLNQDQPLYLERCMQLASHEGYPGHHLFNLLQERELVREAQWFEYAIYPLYSPISFLSEGSANYGLSLIMSDCELIEFEHEHLMPLAGMTGDIEHYHKVLRCYKQLAHLDNSVCQQLIDGKVSPNEAESLLVRFGLYSESRAKQRVKFYQANRAYVINYNHGEDSVARWVERGEADKNERWKRFESLLKRPLMASQFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN99</accession>
    <name>B1KN99_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2 7">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purD</name>
        <name evidence="10" type="ordered locus">Swoo_0295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322945.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0295"/>
    <dbReference type="EnsemblBacteria" id="ACA84596">
        <property type="protein sequence ID" value="ACA84596"/>
        <property type="gene ID" value="Swoo_0295"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0295"/>
    <dbReference type="eggNOG" id="COG0151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027420_3_1_6"/>
    <dbReference type="OMA" id="KATVCKY"/>
    <dbReference type="OrthoDB" id="932854at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="109"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="430" mass="45462" checksum="7186DCDC639EAD7B" modified="2008-04-29" version="1">MNVLVIGGGGREHALAWKAAQSAQVETVFVAPGNAGTSMEPKLENVAIQVEDIPALVAFAQDKAIEITIVGPEVPLALGVVDAFNDAQLPIFGPTQGAAQLESSKAFTKDFLARHNIPTAAYSNFTEIEPAKAYVTQVTANTGFPIVIKADGLAAGKGVIIAEDQIQADAAIEDMLAGNKFGEAGSRVVIEEFLKGEEASFIVMVDGKNILAMATSQDHKARDNGDYGPNTGGMGAYSPAPVVTQAVHDWTINNVIRPTVDGMAAEGNVYTGFLYAGLMIAPDGSAKVLEYNCRFGDPETQPIMMRLQSDLVALCLAATRGELDKVTAEFDSRAAVGVVLAAGGYPEAYRKHDVIDGLDLGNNNAKVFHAGTSMKDGHVVTNGGRVLCATALGNSVTEAQQAAYALVEKIHWDDIYFRTDIAYRAISRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB0</accession>
    <name>B1KNB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322956.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0306"/>
    <dbReference type="EnsemblBacteria" id="ACA84607">
        <property type="protein sequence ID" value="ACA84607"/>
        <property type="gene ID" value="Swoo_0306"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0306"/>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007524_0_4_6"/>
    <dbReference type="OMA" id="HYIMHNT"/>
    <dbReference type="OrthoDB" id="961809at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029493">
        <property type="entry name" value="RecD-like_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14490">
        <property type="entry name" value="HHH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HHH_4" evidence="2">
        <location>
            <begin position="166"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD_C_2" evidence="1">
        <location>
            <begin position="637"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="710" mass="78794" checksum="DB358BDB589C3472" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNB4</accession>
    <name>B1KNB4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322960.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0310"/>
    <dbReference type="EnsemblBacteria" id="ACA84611">
        <property type="protein sequence ID" value="ACA84611"/>
        <property type="gene ID" value="Swoo_0310"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0310"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038043_0_0_6"/>
    <dbReference type="OMA" id="EPAVACY"/>
    <dbReference type="OrthoDB" id="215800at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="167"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="579" mass="65866" checksum="60EBC938638E80D4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KND1</accession>
    <name>B1KND1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Phosphoenolpyruvate carboxylase</fullName>
            <shortName evidence="10">PEPC</shortName>
            <shortName evidence="10">PEPCase</shortName>
            <ecNumber evidence="5 10">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ppc</name>
        <name evidence="13" type="ordered locus">Swoo_0327</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322977.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0327"/>
    <dbReference type="EnsemblBacteria" id="ACA84628">
        <property type="protein sequence ID" value="ACA84628"/>
        <property type="gene ID" value="Swoo_0327"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0327"/>
    <dbReference type="eggNOG" id="COG2352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006557_2_0_6"/>
    <dbReference type="OMA" id="PWVFGWT"/>
    <dbReference type="OrthoDB" id="398146at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="8 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12">
        <location>
            <position position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA84628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="878" mass="98843" checksum="E65F827C57BC9501" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF8</accession>
    <name>B1KNF8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324381.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86035">
        <property type="protein sequence ID" value="ACA86035"/>
        <property type="gene ID" value="Swoo_1750"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1750"/>
    <dbReference type="eggNOG" id="ENOG502ZDFE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153913_0_0_6"/>
    <dbReference type="OMA" id="YYLETWY"/>
    <dbReference type="OrthoDB" id="1410845at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="133" mass="15130" checksum="AE330D15A07425DC" modified="2008-04-29" version="1">MTSVTTVIQDQTFKVDSSELLKVIKMSVVEKRQRLGWQAKEAEKRDIVGRWVDERDSVGDKITLYREDGKIYLETWYNDGCHSLDEMEATPTPEGLKLEDVGGNIFGEYFLLSDGKTLQFCNSSSCFYTAKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNJ5</accession>
    <name>B1KNJ5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0276 protein Swoo_1788</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0276 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324418.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1788"/>
    <dbReference type="EnsemblBacteria" id="ACA86072">
        <property type="protein sequence ID" value="ACA86072"/>
        <property type="gene ID" value="Swoo_1788"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1788"/>
    <dbReference type="eggNOG" id="COG3220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064263_0_0_6"/>
    <dbReference type="OMA" id="YYAAPYQ"/>
    <dbReference type="OrthoDB" id="1602134at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00697">
        <property type="entry name" value="UPF0276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007801">
        <property type="entry name" value="UPF0276"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42194">
        <property type="entry name" value="PTHR42194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05114">
        <property type="entry name" value="DUF692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="278" mass="31881" checksum="596700B8F13A586F" modified="2008-04-29" version="1">MDERAKVGLGLRREMLDEFCQSSPQEINFFEVAPENWMTLGGKYGRQFKQLTEQHEFFCHGLSLSIGGPAALDVQFVKNIKSFMDEHKISVYSEHLSYCSGIGHMYDLMPIPFTEEAVHYVAKRVKQVEDILERALILENVSFYTAPGAQMSELEFVTAVLDEADCKMLLDVNNIYVNSINHQYDAKVFLRAMPTERIEYLHIAGHYEEDKDLIVDTHGADVISPVWELLAECYQTHGVFPTLLERDFNIPETPVLLEEINQIAQYQQLEIANLARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL8</accession>
    <name>B1KNL8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mfd</name>
        <name evidence="11" type="ordered locus">Swoo_1811</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324441.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1811"/>
    <dbReference type="EnsemblBacteria" id="ACA86095">
        <property type="protein sequence ID" value="ACA86095"/>
        <property type="gene ID" value="Swoo_1811"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1811"/>
    <dbReference type="eggNOG" id="COG1197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005122_0_3_6"/>
    <dbReference type="OMA" id="WAPPCRE"/>
    <dbReference type="OrthoDB" id="234717at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="623"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="805"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1157" mass="129750" checksum="903B2DE08F7ADD37" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-06-10" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNM7</accession>
    <name>LPXK_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tetraacyldisaccharide 4'-kinase</fullName>
            <ecNumber evidence="1">2.7.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Lipid A 4'-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lpxK</name>
        <name type="ordered locus">Swoo_1820</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + {2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-beta-D-glucosaminyl}-(1-&gt;6)-{2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl phosphate} = ADP + {2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-4-O-phospho-beta-D-glucosaminyl}-(1-&gt;6)-{2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl phosphate}.</text>
            <dbReference type="EC" id="2.7.1.130"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LpxK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.130" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324450.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNM7"/>
    <dbReference type="SMR" id="B1KNM7"/>
    <dbReference type="STRING" id="392500.Swoo_1820"/>
    <dbReference type="EnsemblBacteria" id="ACA86104">
        <property type="protein sequence ID" value="ACA86104"/>
        <property type="gene ID" value="Swoo_1820"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1820"/>
    <dbReference type="eggNOG" id="COG1663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038816_2_0_6"/>
    <dbReference type="OMA" id="MDDGFQN"/>
    <dbReference type="OrthoDB" id="1382484at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009029">
        <property type="term" value="F:tetraacyldisaccharide 4'-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00409">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003758">
        <property type="entry name" value="LpxK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42724">
        <property type="entry name" value="PTHR42724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02606">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00682">
        <property type="entry name" value="lpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000340864" description="Tetraacyldisaccharide 4'-kinase">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00409"/>
        </source>
    </evidence>
    <sequence length="341" mass="37902" checksum="052F17BEFA242B7A" modified="2008-04-29" version="1">MQDFVNRLWYPKADDCIGYRGIKWLLTPLSLLFWCVSSLRRLLFKLGIKAAVSLPVPVIVVGNITVGGSGKTPTVIYLIELLRAQGLNPGVVSRGYGVKIDGVKIVEPHLGADSVGDEPAMIVARTQVPMVIGSDRVSAAKCLIERFDVDIIISDDGLQHYKMARDVELLILDGERRFGNELLLPAGPLRELTGRQKTVDFTIVNGEAKEGEFQMILEPTRFIPVSPRSELVFEPVEHVVAIAGIGNPERFFTTLAQSGVEVIKTKAFEDHQKFSLTQITQVTGNSPVLMTEKDAVKCRDFAKENWWYLAVDAKLAENFDQRLMDKVRQVIAVKQGNRDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNR4</accession>
    <name>B1KNR4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acyl-D-amino-acid deacylase</fullName>
            <ecNumber evidence="3">3.5.1.81</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.81" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325858.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3252"/>
    <dbReference type="EnsemblBacteria" id="ACA87522">
        <property type="protein sequence ID" value="ACA87522"/>
        <property type="gene ID" value="Swoo_3252"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3252"/>
    <dbReference type="eggNOG" id="COG3653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016107_2_1_6"/>
    <dbReference type="OMA" id="CLDCHPY"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047420">
        <property type="term" value="F:N-acyl-D-amino-acid deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767521" evidence="1">
        <location>
            <begin position="21"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="2">
        <location>
            <begin position="82"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="2">
        <location>
            <begin position="412"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="527" mass="57768" checksum="744CE82F0593C2A0" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNV1</accession>
    <name>B1KNV1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3289"/>
    <dbReference type="EnsemblBacteria" id="ACA87559">
        <property type="protein sequence ID" value="ACA87559"/>
        <property type="gene ID" value="Swoo_3289"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3289"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_11_4_6"/>
    <dbReference type="OMA" id="DRHETQF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="45"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="285" mass="32593" checksum="75FD0B6E8500178F" modified="2008-04-29" version="1">MNNDNQFDEKSVDSSANKEIEAGVNEAELHDETAPEIEILFEDDDIVVIHKPAGLLVHRSYLARRERFFAMQMTRDKVGCHVFPVHRLDRPTSGILLFAKSSEMANNLCEQFSAKTVEKQYLAIVRGNMHEADTLDYALKVELDDHGDKDVDPNKAAQEAVTSYQPLLNTEIPFPSGRYATSRYAMVKLIPHTGRKHQLRRHMAHLRHPIVGDTTHGDGKQNKFFREHFAINRLWLIAKSLAFDHPRSGERITIETELEKEWLTLFEAFGWDDEVLASETSTLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY6</accession>
    <name>B1KNY6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4768</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327334.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4768"/>
    <dbReference type="EnsemblBacteria" id="ACA89017">
        <property type="protein sequence ID" value="ACA89017"/>
        <property type="gene ID" value="Swoo_4768"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4768"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_4_6"/>
    <dbReference type="OMA" id="ACAPKPE"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767527" evidence="3">
        <location>
            <begin position="22"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="44"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="85"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="362" mass="40155" checksum="EBBFEE791E6FA2A7" modified="2008-04-29" version="1" precursor="true">MKTLIPTLLCFTLLSPYTVMAEEEKQETPPRLVSVVQVENRALSPKIMVIGSVHSRNSAELTSGIDGKLDWVQEAGTLVKAGEVVARLEQTRLILQKEQQQAQIEYEQVSLKRLEREYSRLKKLIKSKNASETELDKAQSDRDLAAANLKLEQIKLKMILDNLDRTEVKATFDGIITERQHQAGEDISRSESIIAMTDPDNLEIRLHAPLKHSKRVKKGDELNIYHSQGEFHGNIRSLIPVSDVRSQTFEARIDLPIEMHDAFSVGELVSLALPIAPKQLTTLVPRDAIILRSTGAFVFKIDLENKAVKIPVELGDGEGEWIAVNGQLTDSDSVVIRGAETLQDGQVVQFQAIPGSKVATAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP08</accession>
    <name>B1KP08_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MoaD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327356.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4790"/>
    <dbReference type="EnsemblBacteria" id="ACA89039">
        <property type="protein sequence ID" value="ACA89039"/>
        <property type="gene ID" value="Swoo_4790"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4790"/>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_4_0_6"/>
    <dbReference type="OMA" id="DRVHAKP"/>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="PTHR33359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="8935" checksum="447B9B4258835AD5" modified="2008-04-29" version="1">MINVLFFAQVRELLGESAIQVEATAEINSAETLRAVLASKDEKWGKVLASDKLLVAVNQTISGWDTQVQDGDEVAFFPPVTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP15</accession>
    <name>B1KP15_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327363.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4797"/>
    <dbReference type="EnsemblBacteria" id="ACA89046">
        <property type="protein sequence ID" value="ACA89046"/>
        <property type="gene ID" value="Swoo_4797"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4797"/>
    <dbReference type="eggNOG" id="COG2258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082566_1_1_6"/>
    <dbReference type="OMA" id="CWKLNDR"/>
    <dbReference type="OrthoDB" id="1643056at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005163">
        <property type="entry name" value="YiiM-like_3-alpha_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03475">
        <property type="entry name" value="3-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="32"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="232" mass="26110" checksum="7E09F96BE821ECD5" modified="2008-04-29" version="1">MSEQLLVKRLSGLYLGEEFSESTGIISGIANKKSSIKLEVNIDRVSGDAQADPKHHGGLDRVLHHFPREHYGQYRRWDMMNGFKDGPAMGENISTVGLDEAQVNIGDIIAIGEVQLQVTQPRSPCFKLNQQFGHKEFALAMQTSGLCGWFYRVLKPGVIQQDDSVTLLERRTQMSVRDAMAIYFAPEFDASAYDRLISSEGLATSWVNSLQRRLDSQKIENWQMRLFGPQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP23</accession>
    <name>B1KP23_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327371.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89054">
        <property type="protein sequence ID" value="ACA89054"/>
        <property type="gene ID" value="Swoo_4805"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4805"/>
    <dbReference type="eggNOG" id="ENOG5032YSM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164560_2_0_6"/>
    <dbReference type="OrthoDB" id="2020936at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12458" checksum="C66468DE60ED5364" modified="2008-04-29" version="1">METVSWTAKTGVEAEQMIDAVEKMVPDLQKVPGFRYQSLCLKELMPESDATDSKSQWLQLYYWDTVEAAHKSNAIMAPTDSLNHLISLIEPDSIAIDIFTPLQQSSPLTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP54</accession>
    <name>B1KP54_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4836"/>
    <dbReference type="EnsemblBacteria" id="ACA89085">
        <property type="protein sequence ID" value="ACA89085"/>
        <property type="gene ID" value="Swoo_4836"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4836"/>
    <dbReference type="eggNOG" id="ENOG5032T0Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115421_0_0_6"/>
    <dbReference type="OMA" id="TWEYVIL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021501">
        <property type="entry name" value="DUF3157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11355">
        <property type="entry name" value="DUF3157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765097" evidence="1">
        <location>
            <begin position="43"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="24796" checksum="C53C2C582C4670AD" modified="2008-04-29" version="1" precursor="true">MKYLSIQFMLEPTYLFGFKPMRKTLNTLIGFALLTLAIPAMAAEVTTVTLDNGTKVRLNDDFTWEYVILETTTPAVDTVTTTSAPTSQASTQAAVISAPTLTARAMSQAELLKSTAKGGVKVSFLNSQWDEDGRLGLTFDLASSSSEHYVLINLDVTLFDDTGKLLETKTIKVWKAIFRMPDTYLRKGQQRESKIFWFEGIDPNLWTKELVSLKIGEMDSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPB1</accession>
    <name>B1KPB1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UPF0313 protein Swoo_0382</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0382</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0313 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323030.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0382"/>
    <dbReference type="EnsemblBacteria" id="ACA84681">
        <property type="protein sequence ID" value="ACA84681"/>
        <property type="gene ID" value="Swoo_0382"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0382"/>
    <dbReference type="eggNOG" id="COG1032">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018288_2_0_6"/>
    <dbReference type="OMA" id="TCMYYTG"/>
    <dbReference type="OrthoDB" id="229299at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01251">
        <property type="entry name" value="UPF0313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022946">
        <property type="entry name" value="UPF0313"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024560">
        <property type="entry name" value="UPF0313_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013704">
        <property type="entry name" value="UPF0313_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32331">
        <property type="entry name" value="PTHR32331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11842">
        <property type="entry name" value="DUF3362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08497">
        <property type="entry name" value="Radical_SAM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01069">
        <property type="entry name" value="UPF0313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03904">
        <property type="entry name" value="SAM_YgiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="371"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="677"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="694"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="730"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="763" mass="85369" checksum="23E7ED990FAED237" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPF0</accession>
    <name>B1KPF0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BAX protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0422"/>
    <dbReference type="CAZy" id="GH73">
        <property type="family name" value="Glycoside Hydrolase Family 73"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84720">
        <property type="protein sequence ID" value="ACA84720"/>
        <property type="gene ID" value="Swoo_0422"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0422"/>
    <dbReference type="eggNOG" id="COG2992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1539020_0_0_6"/>
    <dbReference type="OMA" id="SRYKVKW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="1">
        <location>
            <begin position="28"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19246" checksum="6ED043DFAE58B9EF" modified="2008-04-29" version="1">MANDYGLKERDVKSGKSKAVDIKLLLQNIDVIPTGMVLAQGIDESGWGTGHFAIQGNALYGEHLPQSGGKYLTTPGGHVKVAAFDSLYQGTAAYIYNLNSSRAYHGLWQLRQQLRVQGKSVTGYELVGALVDYSVRGQAYVDNLRSLIEHHHLDSYDNAKFNSAEGRHLIRFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPW7</accession>
    <name>B1KPW7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3381"/>
    <dbReference type="EnsemblBacteria" id="ACA87650">
        <property type="protein sequence ID" value="ACA87650"/>
        <property type="gene ID" value="Swoo_3381"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3381"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_42_2_6"/>
    <dbReference type="OMA" id="LIWTIRP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="271"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="466" mass="51779" checksum="A1B8D00C62739CA8" modified="2008-04-29" version="1" precursor="true">MKSLPAMTPGKPSPLNSLKARLIVSALLLILILMPLIGFTLNDAFKQQVKTAAKSELSAYIYSVLAVTEVENNQLQMPELLLENQFNVIQSGLYALISTPEGDKTSSNKVTKEWKQVWHSDSFLGIDEPANLPQPAIGQREFAQITLAGKAHIIYSLSVSFEQEGGSFPITLHIIKDQADFQLQIDKFNQTLWSWLLLLMVLLALAQLAWLLWTLKPLAKFKQELQDVENGKTMQLSTDYPNELQAVAYQLNTLLITEQNQRKRYRNALSDLAHSLKTPLAVIQSQKGLDSTSVEQVSNINRIIGHQLKRAQSAAGSSWHLGVKLAPICDKLIRTLGKIYREPELKLNSNVDKDAIFRGDEADLTEVLGNLLDNACKAAKEQVMLDISLSHQELSISIEDDGPGVSEELQSKIFERGTRADSYEQGHGIGLAIVRDLLDSYNGKLVISRSKTLGGARFCITFNQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ57</accession>
    <name>B1KQ57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327486.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89170">
        <property type="protein sequence ID" value="ACA89170"/>
        <property type="gene ID" value="Swoo_4921"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4921"/>
    <dbReference type="eggNOG" id="ENOG5033N61">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153914_0_0_6"/>
    <dbReference type="OMA" id="DKSWHND"/>
    <dbReference type="OrthoDB" id="2047337at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="130" mass="14877" checksum="EB5E4835397FCC03" modified="2008-04-29" version="1">MLQYKQEFGEGFELGFELGHFPFLQDKSWHNDVCPSFMFKALIDLNNPDLNQSKQKEQYLVLWVDYENGGDRENTTTSRYSIVTATNLGSLHEPEIYHNESSITVFEAEDPKALTQYLSALSTLSISETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD3</accession>
    <name>B1KQD3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0490"/>
    <dbReference type="EnsemblBacteria" id="ACA84788">
        <property type="protein sequence ID" value="ACA84788"/>
        <property type="gene ID" value="Swoo_0490"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0490"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_2_6"/>
    <dbReference type="OMA" id="PQETHDT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="239" mass="26825" checksum="5DB37C6B7AFEDE6D" modified="2008-04-29" version="1">MIRCYIKPEEISAISFDLDDTLYDNSPIIEKAEAELAHFLHHKYPRTSQFEREDWFALKRKLQKERPELCHDTGLARVSVLTLGLRQLGYSVKEAEAGGLEGLQCFLQYRSDFTLSQPVLELLHGLKQKYRLVGITNGNVDASRIGLGSLFDFVLSPGNGVRMKPAPDMFNVALDRLNIPAVQLLHVGDSHSSDVVGARLAGCQSLWLNPAFGRSKVEQAKAYLPHIEIDNIKQLKLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQG3</accession>
    <name>B1KQG3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324548.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1918"/>
    <dbReference type="EnsemblBacteria" id="ACA86202">
        <property type="protein sequence ID" value="ACA86202"/>
        <property type="gene ID" value="Swoo_1918"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1918"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071578_1_2_6"/>
    <dbReference type="OMA" id="CGYQSEG"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="161"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="259" mass="29625" checksum="F782AE800F8C5D33" modified="2008-04-29" version="1">MAKLINVHAFKSSQPQALRDVPIYIPSIVVIQAGAKLLSWQSDTLTFERGTWLFAHAEQSLTFINHPANFTFRSIQICFLSPPSSAIMESMVDERGRRLTKSPKVVSNTKLDFALKQLLAMQELDFTEQTQQHYLDAFYQILLEAGLLQLLFPGADLSMRERVCRFLSNEPAKAHSIDELCTHLGQSRSTLTRRLADESTSYRELLSETRMLHALSLMQTRPYKQLELALACGYQSETRFGQRFLKQFGLTPKQYMKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQK4</accession>
    <name>B1KQK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324589.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1959"/>
    <dbReference type="EnsemblBacteria" id="ACA86243">
        <property type="protein sequence ID" value="ACA86243"/>
        <property type="gene ID" value="Swoo_1959"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1959"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059701_1_0_6"/>
    <dbReference type="OMA" id="SEPHIHI"/>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="278" mass="31813" checksum="73536933376D6111" modified="2008-04-29" version="1">MEKLTLLIDFLFTHKLLLTLLIIVLISATKRLIIYKVRGDVSFLSDTQRKWISRTKNGTFTLLVILLFMLWQTEINKFALSVTAIAIAIVVASKEIILCFTGSIQRASSRSFVIGDWIEVGSLCGEVIEHNLMATVIQEIDLHHGQYHYTGKTATFPNSTFFTYPVKNLNFMKRYVYHNFTITVPKFVNLYPLFPSLTVQIEQHCEDFHEVAKRYNSIIEKHAGVDLPGSEPHIHVSSGATGEQHVHIMIFCPTERASHLEQSIREDFMLAYEKEFAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQQ2</accession>
    <name>B1KQQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyridoxal-dependent decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2007</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324637.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2007"/>
    <dbReference type="EnsemblBacteria" id="ACA86291">
        <property type="protein sequence ID" value="ACA86291"/>
        <property type="gene ID" value="Swoo_2007"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2007"/>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028929_2_1_6"/>
    <dbReference type="OrthoDB" id="1478871at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020931">
        <property type="entry name" value="MfnA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03812">
        <property type="entry name" value="tyr_de_CO2_Arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="403" mass="44648" checksum="2E5328F54A1A52B8" modified="2008-04-29" version="1">MRKHGLSKSEVYSNIQKLRQTDVPWDRVLNSICTQPHEVAVKAFTDAIDTNLGDVRIFQGTHQIEQQVIQSISTFLHAKEPAGSLVSGGTEANLLALYVAKKQARSKAKNRHVSEVICAETVHYSMKKIFDLLDLTAVILPVDEKFRMDISQINKHISENTVAIVATAGSSEFGSIDPIEELSDIAVAHQIYLHVDAATGGFIIPFAKALGYQLPNFDFSLPGVSSITMDPHKYGLANIPAGGIFFRDQSLIELISLDSFFINTPSHKTFLGTRPGGAAVATFAVLEHLGWDGYKEITRKNYATMEYLVEQLKWRNYQLASPPELNIVIVDLPNAEEVMTLLEEWDWIISVSKRFRHCLRLVITAHVNIEMIDNFLTVLDGAVNCLSDTASLENTQASHGAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQQ7</accession>
    <name>B1KQQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pyridoxal-5'-phosphate-dependent protein beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2012</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2012"/>
    <dbReference type="EnsemblBacteria" id="ACA86296">
        <property type="protein sequence ID" value="ACA86296"/>
        <property type="gene ID" value="Swoo_2012"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2012"/>
    <dbReference type="eggNOG" id="COG1350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042858_1_0_6"/>
    <dbReference type="OMA" id="RYHAVAP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006316">
        <property type="entry name" value="Trp_synth_b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF6">
        <property type="entry name" value="PTHR48077:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="9">
        <location>
            <begin position="88"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="440" mass="48389" checksum="DDB6314FC8189235" modified="2008-04-29" version="1">MDQLKDKLRSNNVNKLDYQLSLEDMPTQWFNFFPHLPKPLPPVRDNGKRSTLEISQLIRPKILLEQNAPKENWIDIPEEVINKLIMCGRPTPLRRALSLEKHLKTPARIYFKREDTMATGSFKLSTAVAQAYYAKQEGREILISETGAGQWGMSVALVSQMFGLDARIFMARCSLEQKPYRQHYMKMLGCEVYPSPSTKTECGKELLLQTPGHPGSIGSAISEAIENALDTPGSAYLSGSNVNHVHLHQTLLGLEVKQQLSMAGESNVDHLVACVSGGSNLCGFMMPFLPEKNSGAKIDMLGVESTASPRLTQGTYEYCRSDVAGYTPEVLSHSMGESYIPAPVHVGGLRNHNSSPLVSLLCREGILRAEALDEFNAFKAGQIMLKTEGILVAPESSHAVAAAIDLAEKARIENKESVIVFLASGNGFLDLQGYNDVLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR2</accession>
    <name>B1KQR2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 28">Na(+)-translocating NADH-quinone reductase subunit F</fullName>
            <shortName evidence="28">Na(+)-NQR subunit F</shortName>
            <shortName evidence="28">Na(+)-translocating NQR subunit F</shortName>
            <ecNumber evidence="7 28">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="27 28">NQR complex subunit F</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="26 28">NQR-1 subunit F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="28" type="primary">nqrF</name>
        <name evidence="31" type="ordered locus">Swoo_3400</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="31 32" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="32">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 28">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 28">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="28">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="28">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 28">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6 28">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="28">Cell inner membrane</location>
            <topology evidence="28">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 28">Belongs to the NqrF family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="7 28"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326003.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3400"/>
    <dbReference type="EnsemblBacteria" id="ACA87668">
        <property type="protein sequence ID" value="ACA87668"/>
        <property type="gene ID" value="Swoo_3400"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3400"/>
    <dbReference type="eggNOG" id="COG2871">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_7_2_6"/>
    <dbReference type="OMA" id="KKWQCEV"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00430">
        <property type="entry name" value="NqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010205">
        <property type="entry name" value="NqrF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000044">
        <property type="entry name" value="Cis_Diol_DH_RD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01941">
        <property type="entry name" value="nqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 28" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10 28" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9 28" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15 28" id="KW-0274">FAD</keyword>
    <keyword evidence="11 28" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="22 28" id="KW-0406">Ion transport</keyword>
    <keyword evidence="18 28" id="KW-0408">Iron</keyword>
    <keyword evidence="19 28" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="24 28" id="KW-0472">Membrane</keyword>
    <keyword evidence="14 28" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20 28" id="KW-0520">NAD</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="21 28" id="KW-0915">Sodium</keyword>
    <keyword evidence="25 28" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="16 28" id="KW-1278">Translocase</keyword>
    <keyword evidence="12 28" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17 28" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="28" id="KW-0813">Transport</keyword>
    <keyword evidence="23 28 31" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="28">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="29">
        <location>
            <begin position="32"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="30">
        <location>
            <begin position="129"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00019729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00030032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00030787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="ACA87668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="405" mass="45061" checksum="D5580B26780850E5" modified="2008-04-29" version="1">MEMAIGIGMFTFVVSVLVMVILIAKSKLVSTGDVSIRINDDDEKSITTSAGDKLLGALANKDIFIPSACGGGGTCGQCRVVVKSGGGDILPTERDHITKKEAKEGCRLACQVAVKTDMELEVEDEIFGVKKWQCEVISNDNKATFIKELLLKLPEGEDVKFKAGGYIQIEAPAHQVNYSDFDIPEEYRGDWEKYELFNLVSKVDEDVLRAYSMANYPDEKGRIMLNVRIATPPSEGLPPGKMSSYIFNLKAGDKVTISGPFGEFFVKDTDAEMVFIGGGAGMAPMRSHIFNQLKGEKTQRKMSFWYGARSTREVFYQEDFDKLAAENDNFVWHVALSDPLPEDNWDGYTGFIHNVLYENYLKNHKAPEDCEFYMCGPPIMNSSVISMLESLGVEEENILLDDFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR51</accession>
    <name>B1KR51_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323216.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0572"/>
    <dbReference type="EnsemblBacteria" id="ACA84868">
        <property type="protein sequence ID" value="ACA84868"/>
        <property type="gene ID" value="Swoo_0572"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0572"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_0_0_6"/>
    <dbReference type="OMA" id="HYFREVP"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="95"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="34987" checksum="6B8A009F40748A20" modified="2008-04-29" version="1">MSSSVLATQASYVVLPEHITDKPTVLSFLVERFAQIDASVWQSRVVEGKVHWQDGSLIELDTPYRPRARVYYYREVVSETKVPFDEEVIYQDERIIVAFKPHFLALHPSGNVINECLVNRLRIKTGLETIVPAHRLDRATAGLVLLCLHPEHRQRYHDLFKFGQIRKEYQALAKLTPELLLKHQRGELSLPLNWTVKNRMVKGEPTFTMRVAPGEPNTHSEIQLIEINGELGVFNLSPITGRTHQLRVHMQSLGMPILNDRCYPELQPKAPDDYSKPLKLLARRLTFTDPVSGQLIKLECDALSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRB1</accession>
    <name>B1KRB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324664.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2034"/>
    <dbReference type="EnsemblBacteria" id="ACA86318">
        <property type="protein sequence ID" value="ACA86318"/>
        <property type="gene ID" value="Swoo_2034"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2034"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_19_2_6"/>
    <dbReference type="OMA" id="LLIFDWD"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="216" mass="23534" checksum="4D7E2663B1596862" modified="2008-04-29" version="1">MKQYELVIFDWDGTLMDSVGKIVACMQQTAKVLEFPTPSESAVRNIIGLSMQEALNTLYPDGSDSVYRQMIQVYRQQYLELDTTPSPLFDGAELLLQQLNQVGYQLAVATGKARAGLDRVLNETGLGQQFIASRCADEAVSKPHPEMILQLLNELNVEPAKALMIGDSVHDINMANNAGIDAVAVNYGAHGESQLLTSKPKGIISSPLELLGFLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK7</accession>
    <name>B1KRK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Conserved hypothetical amino acid ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326105.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3508"/>
    <dbReference type="EnsemblBacteria" id="ACA87772">
        <property type="protein sequence ID" value="ACA87772"/>
        <property type="gene ID" value="Swoo_3508"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3508"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064076_5_0_6"/>
    <dbReference type="OMA" id="WPPFANQ"/>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766993" evidence="2">
        <location>
            <begin position="22"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="29"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="250" mass="27568" checksum="836733456413029D" modified="2008-04-29" version="1" precursor="true">MLHTRLTLLFITSLLCSFATADESLKTVKLAAEDNWAPFAKASGTGVSHSLINQAFSTVGVEVDSIVVPYSRAVVMAKEGLVDGVFNLVKEQSTESEFIFGKQPLFSATASFYHKVSTPVKAKDKWQLPPNTKVGIIRGYEYGDELKQLPNIRLITLSNHNQLINLLLLDRIDVAIMYDLVAKQYISQMGVSQEIEQIFTNHTGQVYLAFSKLNPHASKLAELLDRGLTTLKDDGSYQEIMASAGSPARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRS2</accession>
    <name>B1KRS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326170.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3573"/>
    <dbReference type="EnsemblBacteria" id="ACA87837">
        <property type="protein sequence ID" value="ACA87837"/>
        <property type="gene ID" value="Swoo_3573"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3573"/>
    <dbReference type="eggNOG" id="ENOG5033NB6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126009_0_0_6"/>
    <dbReference type="OrthoDB" id="1905700at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767332" evidence="1">
        <location>
            <begin position="25"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="18337" checksum="08837C3DE13FA69E" modified="2008-04-29" version="1" precursor="true">MHTFLRLVFIWLFLGVFFTSPAFAHDFQKVEGTQFVHELSISPASTQDLGFTSLLETPLLPQKPSVSNKAVKDDQKDSKFVPLISQRLISFAQHDPLQNEPDYRLAFEFAPPLALSLTIGYRIDFAQSLDWSLHMGKKPSRLSGWKETNLLYRFSQTSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD48</accession>
    <name>B1KD48_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Extracytoplasmic solute receptor protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">TRAP transporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3619</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Part of the tripartite ATP-independent periplasmic (TRAP) transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3619"/>
    <dbReference type="EnsemblBacteria" id="ACA87883">
        <property type="protein sequence ID" value="ACA87883"/>
        <property type="gene ID" value="Swoo_3619"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3619"/>
    <dbReference type="eggNOG" id="COG4663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_0_1_6"/>
    <dbReference type="OMA" id="FWEGGPT"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031317">
        <property type="term" value="C:tripartite ATP-independent periplasmic transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026289">
        <property type="entry name" value="SBP_TakP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039026">
        <property type="entry name" value="SiaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR039026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR039026-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR039026-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="364" mass="40430" checksum="AD077F144A00CB7C" modified="2008-04-29" version="1" precursor="true">MIKRVTVCFISLAVLFISGCQEKEVQVAQTGAVEVETIEWKLVTSWPKNFPGLGMAPERFAKLVDEMSAGRLKIKVFGAGELMPAFEVFDAVSQGTVQMGHSAAYYWKGKTPAAQFFTSIPFGLNAQEMNGWLHYGGGLELWEEVYEPFGILPLAGGNTGVQMGGWFNKEINSMEDLKGLKMRLPGLGGEVLKRVGGVPVTLPGRELYTALQTGAIDATEWVGPFNDLAFGLHKAAKFYYYPGWHEPGTTLEFLMNKEAFAALPADLQSIVTIAARAINQDMLDEYTSKHIIALDSLIDEHGVILKQYPDEVMKKLAEVSKVVIKEQSAKDDTMTKVYKAYMEYEAGVRKYHKISEDAYSRLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD71</accession>
    <name>B1KD71_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3644</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326239.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3644"/>
    <dbReference type="EnsemblBacteria" id="ACA87906">
        <property type="protein sequence ID" value="ACA87906"/>
        <property type="gene ID" value="Swoo_3644"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3644"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029352_1_1_6"/>
    <dbReference type="OMA" id="ANPFYVD"/>
    <dbReference type="OrthoDB" id="1165704at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="PTHR12778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="23"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="472" mass="51875" checksum="5A81A2B13660B609" modified="2008-04-29" version="1">MPPVASSPLSQIKEALSIYSHKRVLVLLLLGFSAGLPLMLVFSTLSFWLREAGIDRTAIGYFSWIALAYGFKWAWSPLVDRLSLPIFTRLLGRRRGWMLFAQILLVTAILGMSFSDPVKDLERLALFALMVAFASATQDIVIDAFRIESAPEKMQAALAAAYQVGYRSAMIVATAGALTIAAWVEPSSDAYSLLSWQTAYLIMAGLMSVGILTTLMSKEPQVETKLADEKELAIKSEFNQRYPKAIAGTLSWFYTASVLPFIDFFKRYGHNAILILLLISCYRISDIVMGIMANVFYVDMGFAKDEIAAISKVYGLIMTLVGAGFGGVLLARYGTMKVLFLGALLVAVTNLLFAYQAMIGYNVPFLTLAISVDNFSAGIATAAFIAYLSSLTSTGYSATQYALLSSIMLLFPKFIAGFSGAYVDTFGYINFFIAASIIGLPVLWLVHIVDKRTKHDSGMVEQTDKQVYEQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDC3</accession>
    <name>B1KDC3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84924">
        <property type="protein sequence ID" value="ACA84924"/>
        <property type="gene ID" value="Swoo_0628"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0628"/>
    <dbReference type="HOGENOM" id="CLU_1874024_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15420" checksum="977AF8B18DFD54C0" modified="2008-04-29" version="1">MIYFNNLQGRDYKSVYNETVKSRDQGDDPIIFDLHDTQIANAMNHDWQYVTKGQMAMVVQGDKKLNSTVYKITKIERIEDAITQSSGYLVRGAVISKLAVKGSRYDISFMLQGVSHKRLTDGCFQRGVNLISAADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ1</accession>
    <name>B1KDJ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating GFA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0697</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0697"/>
    <dbReference type="EnsemblBacteria" id="ACA84992">
        <property type="protein sequence ID" value="ACA84992"/>
        <property type="gene ID" value="Swoo_0697"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0697"/>
    <dbReference type="eggNOG" id="COG3791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_4_0_6"/>
    <dbReference type="OMA" id="RYICVGS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="33"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="18021" checksum="D87667B55AAADC8E" modified="2008-04-29" version="1">MTGIVGAARLVLIQVITEKNGIGIMEQDSEVIIEGGCLCRSLRYSITAMPFDADHCHCSLCQKSTGAVVASWMDFRIEQVNWLSSSTPKEYASSETTRRGFCPNCGTSISFRDIGHPQYYTLSIASLDDPNLVAPQYHIHTSNQLRWLNIKDNAPRYTSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDK0</accession>
    <name>B1KDK0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF262 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323348.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0706"/>
    <dbReference type="EnsemblBacteria" id="ACA85001">
        <property type="protein sequence ID" value="ACA85001"/>
        <property type="gene ID" value="Swoo_0706"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0706"/>
    <dbReference type="eggNOG" id="COG1479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038557_1_0_6"/>
    <dbReference type="OMA" id="NIALFEC"/>
    <dbReference type="OrthoDB" id="1779628at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="42"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="370" mass="42678" checksum="9D6ACF67993DB4F1" modified="2008-04-29" version="1">MTEQIDDPIEIEAQEELELAVHPHPMGTETQIRIAKEQSSVYELLRKESKGLLVLAPAFQRIDVWDKKHKSELIESILMGIPIPLIYLFEDEYGIRQIVDGKQRITALKEFINNSFSLSELSMLPQLKGLKFEQIPSLLQAKLEDYQLQTYVIQPPTPESVKFNLFERVNRGGVNLNKQEMRHALYQGRATVLLEELAMSQEFQLATGFGVKSNRMRDRYLILRFIAFYLYFTNQLPNIQYRLGIDGFLASVMRFVNQAPKELIEHVRHVSLLGMRNSAIILGENGVRFAPKKPGGNKRPVNMGLFEMLIFTFCYVDLSIVNHQEIKRVIERQKFEIDQMDLLAGSIDTTANVTERFNLAQQLIQRAKYA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU4</accession>
    <name>HEM1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="1">GluTR</shortName>
            <ecNumber evidence="1">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hemA</name>
        <name type="ordered locus">Swoo_3686</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326278.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDU4"/>
    <dbReference type="SMR" id="B1KDU4"/>
    <dbReference type="STRING" id="392500.Swoo_3686"/>
    <dbReference type="EnsemblBacteria" id="ACA87946">
        <property type="protein sequence ID" value="ACA87946"/>
        <property type="gene ID" value="Swoo_3686"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3686"/>
    <dbReference type="eggNOG" id="COG0373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035113_2_2_6"/>
    <dbReference type="OMA" id="FAFKCAA"/>
    <dbReference type="OrthoDB" id="1358620at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000093169" description="Glutamyl-tRNA reductase">
        <location>
            <begin position="1"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="49"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="110"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="185"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <sequence length="416" mass="45574" checksum="9F4ED1426B16FDD3" modified="2008-04-29" version="1">MSLVAIGINHKTATVDLREKVAFSPDKIHDAMKSLAKCTKTGEAVIISTCNRTELYTNTGDEAEVIRWFEEYHQLSHEEVEPCLYKFEGQGVVKHLMRVSSGLDSLILGEPQILGQVKQSFAKAREAGSVAITMDRLFQNTFSVAKKVRTETEIGAAAVSVAFAAVSMAKHIFSSISSTKVLLIGAGETIELVARHLKDNGVDSMVVANRTLSRAEGMCDEFGATAITLEQIPDFLPKADIVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEAEVADLDDAFLYTVDDLQSIIEQNMASRREAAEQAEVIAENESHLFMEWVRSLESVDSIREYRTQSMAIKDELVERAINKLAQGGDSEQLLLELANKLTNKLIHAPTQALTAASRQGDLNSIGQLRSALGLDKN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDV6</accession>
    <name>YBEY_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ybeY</name>
        <name type="ordered locus">Swoo_3698</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326290.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDV6"/>
    <dbReference type="SMR" id="B1KDV6"/>
    <dbReference type="STRING" id="392500.Swoo_3698"/>
    <dbReference type="EnsemblBacteria" id="ACA87958">
        <property type="protein sequence ID" value="ACA87958"/>
        <property type="gene ID" value="Swoo_3698"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3698"/>
    <dbReference type="eggNOG" id="COG0319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106710_0_1_6"/>
    <dbReference type="OMA" id="RMRIHPL"/>
    <dbReference type="OrthoDB" id="1830156at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="PTHR46986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000089209" description="Endoribonuclease YbeY">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <sequence length="158" mass="17864" checksum="A770E2CBD481C1CA" modified="2008-04-29" version="1">MSTSHTKLELALDLQIATDNKQLPTQQDFELWVRTALRNTMTEAELTVRVVDAEESQALNSTYRGKDKPTNVLSFPFEAPAEIELPLLGDLIICASVVEHEAIQQNKPLQAHWAHMVVHGCLHLLGYDHINDIEAEEMESIETQLIESLGFNNPYKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE08</accession>
    <name>B1KE08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tripartite ATP-independent periplasmic transporter DctQ component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3751</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326342.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3751"/>
    <dbReference type="EnsemblBacteria" id="ACA88010">
        <property type="protein sequence ID" value="ACA88010"/>
        <property type="gene ID" value="Swoo_3751"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3751"/>
    <dbReference type="eggNOG" id="COG4665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_2_2_6"/>
    <dbReference type="OMA" id="WNVVGRY"/>
    <dbReference type="OrthoDB" id="2073326at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="19269" checksum="DB73F97A0393723D" modified="2008-04-29" version="1">MKKTHTLLGKLLDSLGYLCAILMILMLFNVFYDVVMRYLFNNISIAMQELEWHLFSAMFMFGIGYTLKEDGHVRVDIFYDNLSRKTQAMINILGVLITVFPFSLLIIYFGAAFVEDAYQLGEKSPDPGGLSYFWIIKSVIPLSFVFVIIAGIYRLIGEVSVLLGSPVEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE65</accession>
    <name>B1KE65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323398.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0756"/>
    <dbReference type="EnsemblBacteria" id="ACA85051">
        <property type="protein sequence ID" value="ACA85051"/>
        <property type="gene ID" value="Swoo_0756"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0756"/>
    <dbReference type="eggNOG" id="ENOG50331VM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168123_0_0_6"/>
    <dbReference type="OMA" id="KQRGQGM"/>
    <dbReference type="OrthoDB" id="2085435at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="87" mass="9120" checksum="4F5FF1F07EE81DE2" modified="2008-04-29" version="1">MLKNKQRGQGMTEYIIIVALIAVSAIGVYSFFGQTIRNQVAGLSSEMSGQNANAQITAAQGSAADATTNADEDYNLGNYNEGADQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEA1</accession>
    <name>B1KEA1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0792</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0792"/>
    <dbReference type="EnsemblBacteria" id="ACA85087">
        <property type="protein sequence ID" value="ACA85087"/>
        <property type="gene ID" value="Swoo_0792"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0792"/>
    <dbReference type="eggNOG" id="COG3488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033900_1_0_6"/>
    <dbReference type="OMA" id="SFQLIWP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010538">
        <property type="entry name" value="DHOR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06537">
        <property type="entry name" value="DHOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028099">
        <property type="entry name" value="DUF1111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="411"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="549" mass="58729" checksum="2519E440850EC50C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE5</accession>
    <name>B1KEE5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 inner membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2242</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2242"/>
    <dbReference type="EnsemblBacteria" id="ACA86523">
        <property type="protein sequence ID" value="ACA86523"/>
        <property type="gene ID" value="Swoo_2242"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2242"/>
    <dbReference type="eggNOG" id="COG2095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079909_2_1_6"/>
    <dbReference type="OMA" id="LFVIMDP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="212" mass="22560" checksum="FF80732CA2823222" modified="2008-04-29" version="1">MELDLTLYVKFFLGLVAIINPVGLLPVFVSLTSHQTEVERNQTGKVANFAVVVILLVTIFAGQHILNMFSISLSAFRIAGGSLIAIIAMSMLQGKLGEVKRNQEEDREASGMESVAVVPLALPLMAGPGAISSVIVSAAENNTLMNHIGMSVTVILFGLTSFILFRMAPVIFKLLGKTGINVITRLMGLLMLSIGIEVIAAGFKGLFPSLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU5</accession>
    <name>B1KEU5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0801"/>
    <dbReference type="EnsemblBacteria" id="ACA85096">
        <property type="protein sequence ID" value="ACA85096"/>
        <property type="gene ID" value="Swoo_0801"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0801"/>
    <dbReference type="eggNOG" id="COG2374">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056923_1_0_6"/>
    <dbReference type="OMA" id="CYVVHFK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="355" mass="40268" checksum="27BEE45B8340E818" modified="2008-04-29" version="1">MHNHLKQESDTVELIKVATFNLFNFIEPPSAYYDFENIYTQEQWQKKLAWITSYLNEHQPDVIGFQEVFSPDALATLTQACGLDYFAVLDEPDVFDDFIYSKPVVAIASRYPIIDVHSVEADSQLAEMVGMPANFSFSRKPLRATVSIPKLGPCDCYVVHFKSKRPLFDAQTEYLSGKSQVKLKTGQLLAVEALAQWGASIVRGSEAALLRHAMVERRVQTQYPMMLMGDFNDGLEGGVLASLTSVDTRIKPDNVFGDVTEELQEYQLQDSYELYQKSQYSLSSQQRPATYYYLAAGSVLDYILLSCEFDAKHSRSLAEVGRYETYDRHLINPSFDRDSQSTDHAPVMITLSIRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW0</accession>
    <name>B1KEW0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0816"/>
    <dbReference type="EnsemblBacteria" id="ACA85111">
        <property type="protein sequence ID" value="ACA85111"/>
        <property type="gene ID" value="Swoo_0816"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0816"/>
    <dbReference type="eggNOG" id="COG4367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_493377_0_0_6"/>
    <dbReference type="OMA" id="APYLINH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="572" mass="66039" checksum="5B973F848802BD28" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW2</accession>
    <name>B1KEW2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Porin Gram-negative type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323460.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0818"/>
    <dbReference type="EnsemblBacteria" id="ACA85113">
        <property type="protein sequence ID" value="ACA85113"/>
        <property type="gene ID" value="Swoo_0818"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0818"/>
    <dbReference type="HOGENOM" id="CLU_778210_0_0_6"/>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766511" evidence="3">
        <location>
            <begin position="24"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="4">
        <location>
            <begin position="14"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="356" mass="39371" checksum="11A4C2B2FD69CCA1" modified="2008-04-29" version="1" precursor="true">MKYNNTISLIAISIVLFTSNSSAGELFDWYGTIRAQVQDTNNGELEYKDNYSRLGAAGGAEILDGIKATYNVEFRLFTSDGSFAGSDSRARLANIGLESEYGSLLIGKQYSPQWNYTNNAIDIFADVDQSAGCTNEASGVICHTSRYGLFGYDQAGNGHYVEVLRPDRAVTYTTPDLNGFQASAMAILNDGDVKASADGSDSETLVGYNIAAKYKWQDFTLSAARFEVSSFVEEASIDSVQLVYNHDKLSIAAHYQMSEDLRFYEGLPAAGEMVEEQVYEIYAGYKFSEVQIQAAYSIVDMTSPSNVNVDTDHLLIDVIYPHKYGRFYAEYSIWGDEAEEFFIAADTVILGVQFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF10</accession>
    <name>B1KF10_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">META domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323508.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0867"/>
    <dbReference type="EnsemblBacteria" id="ACA85161">
        <property type="protein sequence ID" value="ACA85161"/>
        <property type="gene ID" value="Swoo_0867"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0867"/>
    <dbReference type="eggNOG" id="COG3187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075808_6_1_6"/>
    <dbReference type="OMA" id="CNHWFAP"/>
    <dbReference type="OrthoDB" id="2029962at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764778" description="META domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="META" evidence="2">
        <location>
            <begin position="33"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="14583" checksum="007A43E35B5018CB" modified="2008-04-29" version="1" precursor="true">MSIKSLIISAALISLTACQSTSAPQTQDIELLGTWNIEVVADKPVIDYSPAQLIFADGGELSGNNSCNNFFGSYSIDGDNVRLMPAGNTMKACVDALMAQEQRVMSSMPTITNAVLAKGKLLLKDEAGKTQIVLSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF35</accession>
    <name>B1KF35_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase SrmB</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">srmB</name>
        <name evidence="12" type="ordered locus">Swoo_0892</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family. SrmB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323533.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0892"/>
    <dbReference type="EnsemblBacteria" id="ACA85186">
        <property type="protein sequence ID" value="ACA85186"/>
        <property type="gene ID" value="Swoo_0892"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0892"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_28_3_6"/>
    <dbReference type="OMA" id="YDIELYQ"/>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00967">
        <property type="entry name" value="DEAD_helicase_SrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028621">
        <property type="entry name" value="DEAD_helicase_SrmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="32"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="232"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="372"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="45775" checksum="2A88380D47727C7B" modified="2008-04-29" version="1">MLFEDLLLDPILLESLKAMGHHKPTTIQQQTIPLAMDQRDILARAPTGTGKTASFLLPALQHIIDFPRRFSGQARVVILTPTRELASQIHRYASHLAYELDLNTVIITGGVPYAPQEEALKGNVDILVATPGRLMEYLDKGLFNAEEVEILVIDEADRMLDMGFSAVVETIAIESVGRKQTMLFSATLEGSDVGRFSHQLLTDPVKVEAEAPRSEKAKIHQWIHIADDKEHKFKLLCSILQQEETQRAIVFVKTREAVASLEGMLQRVGIPCSYMRGDMEQKQRFQALGRFTKGEVNVLLATDVAARGIDVEDITHVINFDMPRSADTYVHRIGRTGRAGAKGTAISLVEAHDIRVVGKIERYMDQPLKRRFIKDLRPKNKEAKPPGKNKVKPSEKSFSKKNKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF60</accession>
    <name>B1KF60_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2322</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324943.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2322"/>
    <dbReference type="EnsemblBacteria" id="ACA86601">
        <property type="protein sequence ID" value="ACA86601"/>
        <property type="gene ID" value="Swoo_2322"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2322"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_9_6"/>
    <dbReference type="OMA" id="QEWPRAY"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="19"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="440"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="523" mass="57626" checksum="DEE7CB7C8845A8AF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF65</accession>
    <name>B1KF65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="3">2.7.8.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2327"/>
    <dbReference type="EnsemblBacteria" id="ACA86606">
        <property type="protein sequence ID" value="ACA86606"/>
        <property type="gene ID" value="Swoo_2327"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2327"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051350_1_0_6"/>
    <dbReference type="OMA" id="YLSTLYI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="PTHR12586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="437" mass="50254" checksum="22482E6C16235255" modified="2008-04-29" version="1">MLDKLGGIPLQPESIRWLLTPKCLKAELLTSIAKAKQAIYISALYLEDDEAGREILSALMKAKAENPALDVKVLVDFHRARRGLIGHKGDSGNYLMYRKVIAEAEHPIEILGVPVKSREFMGVLHLKGFVIDDTVIYSGASLNNIYLHQNEKYRFDRYHVIESAELARSMRQMVQTYLVEDVAVCSLTQKKDCEQLPDKIDIRSLKTRLSKAHYEFEQTRIGNRITPVVGLGRKKNKLNKLVVDLVAQSKESLFICTPYFNPPYILARALAKHLRDGKRIDIVVGDKTANDFYIPPEEDFSTIGALPYMYEQSLRKFAKRQQWAIENGQLNIHLWKDGINSYHLKGMSADSRRHLLTGSNLNPRAWSLDLENGLLLHDETGCWQEQFETEQSHILQHTDRLYHYSQIDTLNSYPAPVRKIMTRIRRLKADFLLRRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF67</accession>
    <name>B1KF67_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324950.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2329"/>
    <dbReference type="EnsemblBacteria" id="ACA86608">
        <property type="protein sequence ID" value="ACA86608"/>
        <property type="gene ID" value="Swoo_2329"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2329"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_47_1_6"/>
    <dbReference type="OMA" id="YYVIVTM"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="408" mass="43293" checksum="E585CBF92B2C5554" modified="2008-04-29" version="1">MSDLQKKSNLSAQHQGFSSLIFLIVIIVACGQMAQTIFVPALPDIANSFSIDAGQLQAIMACYLLSYGLLQFIYGPASDRLGRKPVLIFGITLFVIGAFIASIANSYQLLIAATLLQGAGTASAGALCRSIPRDHYFGEPLVKFNSFVSMAVVFSPLIAPFAGSLMTHYFGWQSVYSFLALFGLFVLLLIITRFKESLPADQRKPEPVTHSYRFVLANRKFKNYLVCLVATFAGIAAFEAVAGVLYGQVLQLSPFWVSCYFVAPIPGYLAGAYYAGKLSDNSKGMYHSVALLGAGALFLLIPGLSNLVIGWSLLVGSVLFFTGAGILFPVLTSAALEPFPRHAGVAGALLGGLQNFGAGIAALMMSLVPMHGQFSVGALCAVMVVLVVLALNAAKSGTDLDKTDVAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF89</accession>
    <name>B1KF89_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324972.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2351"/>
    <dbReference type="EnsemblBacteria" id="ACA86630">
        <property type="protein sequence ID" value="ACA86630"/>
        <property type="gene ID" value="Swoo_2351"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2351"/>
    <dbReference type="HOGENOM" id="CLU_2104451_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764369" evidence="1">
        <location>
            <begin position="24"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12719" checksum="883F69A95716D135" modified="2008-04-29" version="1" precursor="true">MKKSIYLSALLPIMLSITPESLANSCDINIQQGGTPITANQYNTWKNRILNSSNADLRQAYIDNQCTIRQGPHGGGFMPANANNPHITVRIWDGDICHVFTKVGQQPTFPTTCMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFF2</accession>
    <name>B1KFF2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88127">
        <property type="protein sequence ID" value="ACA88127"/>
        <property type="gene ID" value="Swoo_3869"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3869"/>
    <dbReference type="HOGENOM" id="CLU_3296454_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="40" mass="4600" checksum="1C7D14DF7A6B6F61" modified="2008-04-29" version="1">MTLTMSKVEKDISELEEMITEHKLTVSPDAFKPEMLEGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFG7</accession>
    <name>B1KFG7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Purine nucleoside phosphorylase DeoD-type</fullName>
            <shortName evidence="4">PNP</shortName>
            <ecNumber evidence="4">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">deoD</name>
        <name evidence="6" type="ordered locus">Swoo_3884</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase</text>
            <dbReference type="Rhea" id="RHEA:36431"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:142361"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexamer; trimer of homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326472.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3884"/>
    <dbReference type="EnsemblBacteria" id="ACA88142">
        <property type="protein sequence ID" value="ACA88142"/>
        <property type="gene ID" value="Swoo_3884"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3884"/>
    <dbReference type="eggNOG" id="COG0813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068457_2_0_6"/>
    <dbReference type="OMA" id="FAMIADF"/>
    <dbReference type="OrthoDB" id="1028277at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042278">
        <property type="term" value="P:purine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09006">
        <property type="entry name" value="PNP_EcPNPI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01627">
        <property type="entry name" value="Pur_nucleosid_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004402">
        <property type="entry name" value="DeoD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018016">
        <property type="entry name" value="Nucleoside_phosphorylase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF2">
        <property type="entry name" value="PTHR43691:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00107">
        <property type="entry name" value="deoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01232">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="5">
        <location>
            <begin position="16"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="4">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="4">
        <location>
            <begin position="179"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="4">
        <location>
            <begin position="203"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="4">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="25799" checksum="C1800E4826A20254" modified="2008-04-29" version="1">MTPHINAEAGAFATTVLMPGDPLRAKYIAENFLENAVLVTDVRNMLGYTGEYQGKKISVMGSGMGIPSISIYAKELITEYGVKNIIRIGSCGAVSDKIKLMDVVMAMGASTDSAINRTRFEHTDFAMIADFNLLRKAADAADKLKVNYHVGNLYSSDLFYSSDEARYDLMEKYGILGVEMEAAGLYGVAAEYGANALAMMTVTDHIRQGLHLTAEERQQTLNEMIKLTLEAVSQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI2</accession>
    <name>B1KFI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3899</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326487.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3899"/>
    <dbReference type="EnsemblBacteria" id="ACA88157">
        <property type="protein sequence ID" value="ACA88157"/>
        <property type="gene ID" value="Swoo_3899"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3899"/>
    <dbReference type="eggNOG" id="COG3770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111096_0_0_6"/>
    <dbReference type="OMA" id="RHDEHYH"/>
    <dbReference type="OrthoDB" id="1681877at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005073">
        <property type="entry name" value="Peptidase_M74"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03411">
        <property type="entry name" value="Peptidase_M74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764805" evidence="2">
        <location>
            <begin position="20"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="25700" checksum="24798675D1DC9607" modified="2008-04-29" version="1" precursor="true">MNMKYFLLILLWFPLMVMAETSTCFGTTSKGRLVNGVELPSQGVNYVGYSAIARLAGRTYVHSEVKSIIVSAYKDLEKEQPTKVYKYAETGFEEGGQFKPHKTHRNGLSVDFMTPVIDPSGKSVHLPTSPLNKFGYNIEFDEKDTYDGMSIDYEAIAAHVVSLHKQAKKHGHDLWRVIFAPELQPNLYKTKYADYLRNNIQFSKKRSWVRHDEHYHVDFAIPCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN9</accession>
    <name>B1KFN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Endothelin-converting enzyme 1</fullName>
            <ecNumber evidence="10">3.4.24.71</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0911</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.71" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323552.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0911"/>
    <dbReference type="EnsemblBacteria" id="ACA85205">
        <property type="protein sequence ID" value="ACA85205"/>
        <property type="gene ID" value="Swoo_0911"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0911"/>
    <dbReference type="eggNOG" id="COG3590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006187_7_2_6"/>
    <dbReference type="OMA" id="FGWAQVW"/>
    <dbReference type="OrthoDB" id="305005at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M13_N" evidence="9">
        <location>
            <begin position="60"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="8">
        <location>
            <begin position="490"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="694" mass="77824" checksum="455C51C9C08D7008" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFX6</accession>
    <name>B1KFX6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Molydopterin dinucleotide-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2405</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325025.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2405"/>
    <dbReference type="EnsemblBacteria" id="ACA86683">
        <property type="protein sequence ID" value="ACA86683"/>
        <property type="gene ID" value="Swoo_2405"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2405"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006353_0_0_6"/>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00932">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="9">
        <location>
            <begin position="578"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="585"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="588"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="592"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="620"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1299" mass="143266" checksum="2363EFC4C9EF9B63" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB1</accession>
    <name>B1KGB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3991</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326577.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88248">
        <property type="protein sequence ID" value="ACA88248"/>
        <property type="gene ID" value="Swoo_3991"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3991"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_0_1_6"/>
    <dbReference type="OMA" id="DGLWYTF"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="204" mass="21411" checksum="312A543D5B470818" modified="2008-04-29" version="1" precursor="true">MSFTAWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGIYALVTLLGLAVVLKQAPMVFNGIAIIGALYLAWMGVQALRSKGGMSDKLAAGENTSALEAARDGIAISLFNPKIMLFFLALFSQFVMVADNLVGQSLIVLTPLVVDGLWYTIIALVLSHKSVLPKLRSKAALIDKLSGVVLILLAVRVLVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB6</accession>
    <name>B1KGB6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3996"/>
    <dbReference type="EnsemblBacteria" id="ACA88253">
        <property type="protein sequence ID" value="ACA88253"/>
        <property type="gene ID" value="Swoo_3996"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3996"/>
    <dbReference type="eggNOG" id="ENOG50332U8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174030_1_0_6"/>
    <dbReference type="OMA" id="FDTQWYE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="89" mass="10279" checksum="FDC900A2997D2A3A" modified="2008-04-29" version="1">MDNQQDNYMTEETLIETVENQIADGEPKKVKATLMRLVMTGTPREEAIKWIACALAVEIFDIMENEASFNAKRYDQHLDALPNMDWLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL9</accession>
    <name>B1KGL9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M60 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323693.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1054"/>
    <dbReference type="EnsemblBacteria" id="ACA85347">
        <property type="protein sequence ID" value="ACA85347"/>
        <property type="gene ID" value="Swoo_1054"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1054"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004117_0_0_6"/>
    <dbReference type="OMA" id="NPYDAYW"/>
    <dbReference type="OrthoDB" id="14523at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041549">
        <property type="entry name" value="IMPa_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040711">
        <property type="entry name" value="IMPa_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035423">
        <property type="entry name" value="M60-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042279">
        <property type="entry name" value="Pep_M60_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031161">
        <property type="entry name" value="Peptidase_M60_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18642">
        <property type="entry name" value="IMPa_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18650">
        <property type="entry name" value="IMPa_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17291">
        <property type="entry name" value="M60-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01276">
        <property type="entry name" value="M60-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51723">
        <property type="entry name" value="PEPTIDASE_M60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M60" evidence="2">
        <location>
            <begin position="538"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="991" mass="109801" checksum="937007E46BAA280F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGQ2</accession>
    <name>B1KGQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325112.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2494"/>
    <dbReference type="EnsemblBacteria" id="ACA86771">
        <property type="protein sequence ID" value="ACA86771"/>
        <property type="gene ID" value="Swoo_2494"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2494"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_6_0_6"/>
    <dbReference type="OMA" id="TGNQKVG"/>
    <dbReference type="OrthoDB" id="1415498at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="458" mass="49618" checksum="563C09ADAC7BF0AE" modified="2008-04-29" version="1">MNHYGFQAKRLVQLALPVLIAQVTQTMMGFIDTVMAGRVSAVDMAAVAIGTSLWLPALLFVQGLLLAFTPVFAHHHGANNQKAIQPLAFQAGYIAIIGSLGVILFLSFAENIFTMMELEPELARLSIGYLEGFAWGVPAFVLYQVLRGCSEGISYTLPTMIIGFVGLAVNIPANYIFIYGHFGMPAMGGAGCGLATALVFWAMFVAMIVYMQLHKKFAELAPFKSFHKPHLSTIWDMTKHGFPIAMALFFEVSLFAVIALLLAPLGANVVAGHQIALNFSSIVFMLPLSIGIAVSIRVGYYLGQDKTEISALIAKLGLGISFTLAMVTAVITVLFRTEIAYLYNDNPEVVTLAGSLMFLAALYQLSDSVQVVAAGALRGYKDTRSAFYITLFSYWAVGMLLGYILARTDLIVPAMGAHGFWIGLIAGLTTAAVLFALRLRYIQKRGFFKEAIVDASDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS1</accession>
    <name>B1KGS1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type VI secretion system Vgr family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325131.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2513"/>
    <dbReference type="EnsemblBacteria" id="ACA86790">
        <property type="protein sequence ID" value="ACA86790"/>
        <property type="gene ID" value="Swoo_2513"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2513"/>
    <dbReference type="eggNOG" id="COG3501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004121_8_0_6"/>
    <dbReference type="OMA" id="VWTHRYE"/>
    <dbReference type="OrthoDB" id="1880900at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="3">
        <location>
            <begin position="389"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="647"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="682" mass="76420" checksum="2750D584797D3B02" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH69</accession>
    <name>B1KH69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326710.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4125"/>
    <dbReference type="EnsemblBacteria" id="ACA88381">
        <property type="protein sequence ID" value="ACA88381"/>
        <property type="gene ID" value="Swoo_4125"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4125"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041778_1_0_6"/>
    <dbReference type="OMA" id="SLKFPYY"/>
    <dbReference type="OrthoDB" id="1970761at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025737">
        <property type="entry name" value="Phenol_MetA_deg_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13557">
        <property type="entry name" value="Phenol_MetA_deg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764874" evidence="3">
        <location>
            <begin position="27"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="436" mass="48216" checksum="E8E4AC52B92CBD1F" modified="2008-04-29" version="1" precursor="true">MKLTRINAGILVTFSPLCLLTNLSFAQGVEVQKTVTEEQEIAQLKRQLIMLNKQLKQQQQAINHIARQVLTKEANLKSGDANQKPVGSRDASIQRQPVAKAQVSTGAETVSSQSSTKKKAPDRGRSTEDVLQEAHNVFDRPLTVETSFTYSYYSRKDLVLRGFLALDAIFLGNLNLDRIRSNTIQMDLVTRYSATDRWQFEMNIPVMYRWNQYDSVGEGNSSQRYETAETDGGEIGDMSVAAYYRLVKEGSGWPDLVWNVRVKAPTGKHPFGIPLASSPTANLTYPTEIATGSGVWGISTGFSIAKTYDPAIVFFNLNYGWSLPGEFGDLSGLEGNSPGEIDLGDYIDYSVGLAFAVSEKMSLGMSFNQRFYSKTKQRTQGFAWEDIPRSDTNTATLGIGATLALSDSLSMVTNIGAGLTEDSPDYQVSLRFPYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHB5</accession>
    <name>B1KHB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamate--putrescine ligase</fullName>
            <ecNumber evidence="3">6.3.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323769.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1130"/>
    <dbReference type="EnsemblBacteria" id="ACA85423">
        <property type="protein sequence ID" value="ACA85423"/>
        <property type="gene ID" value="Swoo_1130"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1130"/>
    <dbReference type="eggNOG" id="COG0174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_0_0_6"/>
    <dbReference type="OMA" id="LGWGNYA"/>
    <dbReference type="OrthoDB" id="416474at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034024">
        <property type="term" value="F:glutamate-putrescine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="2">
        <location>
            <begin position="110"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="449" mass="50151" checksum="D9DF3484E76A4F8A" modified="2008-04-29" version="1">MKKLTAYLKEHKITEVECVISDMTGIARGKIAPVDKFIDEKGMRMPESVLLQTVTGDYVEDEPYDELLDKADIDFICVPDEDAVFKLPWTIEATAQVIHDTYDKMGNPIELSPRNVLKKVLKLYEDKGWKPVVAPEMEFYLTRRNEDPDQALIPPVGRSGRQESGRQSFSIDAANEYDPLFEDMYDWCEEQGLDIDTLIHEEGTAQMEINFSHGDALSLADQVFVFKRTLREAALKHNVCATFMAKPVADEPGSAMHLHQSVVNIKSGKNIFSLDDGTKGPLFFSYIGGLQKYAPEFLPLLAPNVNSFRRFLPGTSAPINLEWGEENRTCGLRIPESSPQNLRIENRIAGADSNSYLAIAASLLAGYIGMVDDVKPSTPVQGRANESRQSISLPLTLEEALAVMSESTACREYLGEAFTTGYIAVKQADLASYKRVISSWEREYLLLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHD9</accession>
    <name>B1KHD9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="16" type="ordered locus">Swoo_1154</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323793.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1154"/>
    <dbReference type="EnsemblBacteria" id="ACA85447">
        <property type="protein sequence ID" value="ACA85447"/>
        <property type="gene ID" value="Swoo_1154"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1154"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013501_5_1_6"/>
    <dbReference type="OMA" id="LMWPIRD"/>
    <dbReference type="OrthoDB" id="1071997at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013173">
        <property type="entry name" value="DNA_primase_DnaG_DnaB-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08278">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00766">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="257"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA85447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="575" mass="65177" checksum="E8640C60CC51A556" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHF9</accession>
    <name>B1KHF9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323813.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1174"/>
    <dbReference type="EnsemblBacteria" id="ACA85467">
        <property type="protein sequence ID" value="ACA85467"/>
        <property type="gene ID" value="Swoo_1174"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1174"/>
    <dbReference type="eggNOG" id="ENOG5032WB7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135693_0_0_6"/>
    <dbReference type="OMA" id="MSRERWL"/>
    <dbReference type="OrthoDB" id="1939800at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767353" evidence="1">
        <location>
            <begin position="22"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="14433" checksum="6975B69B5AEA6116" modified="2008-04-29" version="1" precursor="true">MKKHLYTVALLLASSAFGAAATEQYPIDKATGLIMAPGWEMVKNQCNACHTSLIIPQNVGSREVWRDTIQWMIDTQGLWDLNETWDPVLDYLETYYNESGIDMKIFRRKPLEAAQMPPLPQKMEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHI6</accession>
    <name>B1KHI6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Channel protein, hemolysin III family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0073 (Hly-III) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325211.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2594"/>
    <dbReference type="EnsemblBacteria" id="ACA86871">
        <property type="protein sequence ID" value="ACA86871"/>
        <property type="gene ID" value="Swoo_2594"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2594"/>
    <dbReference type="eggNOG" id="COG1272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051078_1_2_6"/>
    <dbReference type="OMA" id="HEVFHSL"/>
    <dbReference type="OrthoDB" id="1659567at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005744">
        <property type="entry name" value="Hy-lIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01065">
        <property type="entry name" value="hlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="24819" checksum="33AF80E65FBAAD14" modified="2008-04-29" version="1">MSSQEICHQAPAEQVLNSSGYTLHEELANSVSHALGIIAGIIGLIFSVIKGQDTLTSVQMLGVVIYCSSIILLFSCSTAYHSVSNPKWKHRLKIADHCAIYFLIAGTYTPLMLIALKGEQATVILIAIWSLAVAGVLFKTLFIHRFKKFSVMLYLAMGWLCVTVMSDMIAAMSPLGFQLLLAGGLFYSLGVVFYVGKRIPYNHAIWHLFVLAGAISHFLCVYLTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ9</accession>
    <name>B1KHJ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">DNA polymerase III subunit epsilon</fullName>
            <ecNumber evidence="3 8">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnaQ</name>
        <name evidence="10" type="ordered locus">Swoo_2607</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325224.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2607"/>
    <dbReference type="EnsemblBacteria" id="ACA86884">
        <property type="protein sequence ID" value="ACA86884"/>
        <property type="gene ID" value="Swoo_2607"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2607"/>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047806_2_0_6"/>
    <dbReference type="OMA" id="FHVYLNP"/>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06131">
        <property type="entry name" value="DNA_pol_III_epsilon_Ecoli_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006309">
        <property type="entry name" value="DnaQ_proteo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01406">
        <property type="entry name" value="dnaQ_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Exonuclease" evidence="9">
        <location>
            <begin position="9"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="242" mass="26942" checksum="AAA081F7FCF4393C" modified="2008-04-29" version="1">MNIVSSSKRQIILDTETTGMNQGAGAIFLGHRIIEIGCVEVINRRLTGRHYHEYINPQQIIDEEAIEVHGITNEFVAHKPKFAEVAQSFIEFIDGAEIVAHNANFDVSFMDHEFSLLQPVGPKTADICPILDTLEIAKFLHPGQKNNLDALCKRYGIDNSRRDLHGALLDAEILADVYLMMTGGQTKFNLSSEKEGSESGGIRRLSQSRNKLKVITATADELAMHEERLNLVAKSGQCIWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHK1</accession>
    <name>B1KHK1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325226.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2609"/>
    <dbReference type="EnsemblBacteria" id="ACA86886">
        <property type="protein sequence ID" value="ACA86886"/>
        <property type="gene ID" value="Swoo_2609"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2609"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_6"/>
    <dbReference type="OMA" id="IEGPCHH"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="33291" checksum="ADCF73C9D4053EF4" modified="2008-04-29" version="1">MRITLKQLTIFEAVARSGQVARAAEMVNLSAPATSMALAELEKQLDARLFERVGNRLSLNSQGSLLLPLATEALQKFDQIEHLFSSPEAEYSGTLNVSASSTIGNFMLAKSAVAFCQQYTQAQVDLDIDNTQAVIKSVLEFRSEIGFIEGQCLDSRIKVEAWHKDRLLVFCHPAHPLAGQHVTPQALRGQPWVMREEGSGTRDYFINAANALDMQPVEKFVFRTPDAIKQAVKQGAGLAVLSELTLEKEVSRKELAIIEVEGLFLERQFYRIHHKSRKSTPLCDRFVGFCTTLLNVEPV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHT1</accession>
    <name>TPMT_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiopurine S-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Thiopurine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tpm</name>
        <name type="ordered locus">Swoo_4153</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.</text>
            <dbReference type="EC" id="2.1.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.67" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326738.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHT1"/>
    <dbReference type="SMR" id="B1KHT1"/>
    <dbReference type="STRING" id="392500.Swoo_4153"/>
    <dbReference type="EnsemblBacteria" id="ACA88409">
        <property type="protein sequence ID" value="ACA88409"/>
        <property type="gene ID" value="Swoo_4153"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4153"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085515_1_0_6"/>
    <dbReference type="OMA" id="LWCGDFF"/>
    <dbReference type="OrthoDB" id="2049098at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008119">
        <property type="term" value="F:thiopurine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00812">
        <property type="entry name" value="Thiopur_methtran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022474">
        <property type="entry name" value="Thiopur_S-MeTfrase_Se/Te_detox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025835">
        <property type="entry name" value="Thiopurine_S-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023956">
        <property type="entry name" value="Thiopurine_S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03840">
        <property type="entry name" value="TMPT_Se_Te"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000134081" description="Thiopurine S-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00812"/>
        </source>
    </evidence>
    <sequence length="223" mass="25370" checksum="5038EA48933B2C8F" modified="2008-04-29" version="1">MEPDFWHSKWNAEQIGFHLNEVNPLLIKYWPALDLAPNSQVFVPLCGKSLDLCYLAELGHKVVGCELNQTAVEQFFAENSLPHLMTPAKESISELNRFDASDITLYQGDLFSLTPEELSGVDAFYDRAALIAWPESMRLAYVEKLIELLPPKSMGLLVTLDYPQEALKGPPFAVSNDWVMANMADYFELELLSSEDVLNENPRFVNKQVPWLTESVYQLKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB2</accession>
    <name>B1KIB2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translocation and assembly module subunit TamA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autotransporter assembly factor TamA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_2687</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TamA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2687"/>
    <dbReference type="EnsemblBacteria" id="ACA86963">
        <property type="protein sequence ID" value="ACA86963"/>
        <property type="gene ID" value="Swoo_2687"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2687"/>
    <dbReference type="eggNOG" id="COG0729">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018618_1_0_6"/>
    <dbReference type="OMA" id="NTTMLLY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035243">
        <property type="entry name" value="TamA_POTRA_Dom_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17243">
        <property type="entry name" value="POTRA_TamA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764520" description="Translocation and assembly module subunit TamA" evidence="8">
        <location>
            <begin position="28"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_TamA_1" evidence="11">
        <location>
            <begin position="33"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="10">
        <location>
            <begin position="133"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="10">
        <location>
            <begin position="195"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="9">
        <location>
            <begin position="412"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="617" mass="69458" checksum="19D167FA27269BB5" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIG7</accession>
    <name>B1KIG7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na+/H+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2742</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325354.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87018">
        <property type="protein sequence ID" value="ACA87018"/>
        <property type="gene ID" value="Swoo_2742"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2742"/>
    <dbReference type="eggNOG" id="COG2056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037927_0_0_6"/>
    <dbReference type="OMA" id="MMAFIAF"/>
    <dbReference type="OrthoDB" id="1000841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032813">
        <property type="entry name" value="Na_H_antiport_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13726">
        <property type="entry name" value="Na_H_antiport_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiport_2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="150"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="439" mass="46190" checksum="4CE92597BA8DF7ED" modified="2008-04-29" version="1" precursor="true">MNAVVIAVCLMLGLSLARVNVVVALTISALVAGLIGGLDLHQTVEAFNTGLGGGAQIALSYALLGAFAVALSHSGLTTLISSKVISLLGKEQNSTNNKRVRWVLLLAILSMAIASQNILPIHIAFIPILIPPLLHVMSKLKMDRRLVACVLTFGLVTTYMVLPVGFGGIFLYDILLTNLNSNNLLAIREQVAPAMMIPALGMFAGLLVAIFISYRKPREYKEQLILATEPEEGVKPRNIAIALIAVIATLMVQLYTGSMIFGALVGFIVFSFSGALKHVADQDIFNQGVRMMANIGFIMISAAGFAAVIKETGDVASLVEVMNTAIGDNKALAAFLMLLVGLLITMGIGSSFSTIPIIAAIYVPLAMSFGFSVEATIALVGTAAALGDAGSPASESTLGPTAGLNADGQHDHMKDSVIPTFIHYNIPLLVFGWIAAMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK2</accession>
    <name>B1KIK2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PTS IIA-like nitrogen-regulatory protein PtsN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326825.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4242"/>
    <dbReference type="EnsemblBacteria" id="ACA88498">
        <property type="protein sequence ID" value="ACA88498"/>
        <property type="gene ID" value="Swoo_4242"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4242"/>
    <dbReference type="eggNOG" id="COG1762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072531_5_2_6"/>
    <dbReference type="OMA" id="FDAPDEQ"/>
    <dbReference type="OrthoDB" id="1810962at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006320">
        <property type="entry name" value="PTS_Nitro_regul"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01419">
        <property type="entry name" value="nitro_reg_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="16111" checksum="2CE9AD3EE192F8BC" modified="2008-04-29" version="1">MELSTILQPECTTCATPGSKKKVLELISDLAAVQYPSLSSQEIFESLLAREKMGSTGIGNGIAIPHGRLTNISQPVAVLIKCEEPISFDSIDKQPVDILFALLVPADQCEQHLSTLSAMAEKLNDKLILKQLRKTQDESELYQVITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK4</accession>
    <name>B1KIK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase system, phosphocarrier protein HPr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326827.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4244"/>
    <dbReference type="EnsemblBacteria" id="ACA88500">
        <property type="protein sequence ID" value="ACA88500"/>
        <property type="gene ID" value="Swoo_4244"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4244"/>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136230_1_3_6"/>
    <dbReference type="OMA" id="SIMAMMM"/>
    <dbReference type="OrthoDB" id="404807at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="3"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="91" mass="9416" checksum="0CA79EA52833C19E" modified="2008-04-29" version="1">MTKLERQVTICNKLGLHARAATKLAVLASEFDAKVTIVQGEKQASAASVLGLLMLETGIGKTITLLGEGQDASAALDAICALVDAKFDEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIK6</accession>
    <name>B1KIK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326829.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4246"/>
    <dbReference type="EnsemblBacteria" id="ACA88502">
        <property type="protein sequence ID" value="ACA88502"/>
        <property type="gene ID" value="Swoo_4246"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4246"/>
    <dbReference type="eggNOG" id="ENOG5032CT6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2345106_0_0_6"/>
    <dbReference type="OMA" id="MWLATSE"/>
    <dbReference type="OrthoDB" id="2171461at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="97" mass="10987" checksum="660BA9DF28B3F1E8" modified="2008-04-29" version="1">MAPFFSAKYYTNQYKDLIAQREFSGSEARSLIVPALMTFTTSMWLATSEEHSYSTVKLVNAGSAPLKLACKECFWLSTSSLNELTREQPFHHPFALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIL6</accession>
    <name>B1KIL6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_30 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326839.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4256"/>
    <dbReference type="EnsemblBacteria" id="ACA88512">
        <property type="protein sequence ID" value="ACA88512"/>
        <property type="gene ID" value="Swoo_4256"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4256"/>
    <dbReference type="eggNOG" id="COG4121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061971_1_0_6"/>
    <dbReference type="OMA" id="LIYFDAF"/>
    <dbReference type="OrthoDB" id="864499at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016645">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008471">
        <property type="entry name" value="MnmC-like_methylTransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05430">
        <property type="entry name" value="Methyltransf_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_30" evidence="1">
        <location>
            <begin position="150"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="227" mass="25667" checksum="6BC5C1F3DF43111D" modified="2008-04-29" version="1">MINKIEVKMTKDGSHTLMSSLFDDSYHAHNGAMSESEYVYIQAGFEQLSATFSEVNILELGFGTGMNAILTLRSALAQTGRVERPIRFTSIEAYPIPMELVEQLNYKAGFTPEIAALFDKLHQAPWDCDVEIVPGFMLHKVHGKLQSFTSAENSINLVYYDAFAPSKQPELWQQDNFDRLFPMMQQQAMLVSYCANGQFKRNLKASGFTVKAYPGALGRREMTRAWK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIS8</accession>
    <name>Y1284_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0246 protein Swoo_1284</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1284</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0246 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323922.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIS8"/>
    <dbReference type="SMR" id="B1KIS8"/>
    <dbReference type="STRING" id="392500.Swoo_1284"/>
    <dbReference type="EnsemblBacteria" id="ACA85576">
        <property type="protein sequence ID" value="ACA85576"/>
        <property type="gene ID" value="Swoo_1284"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1284"/>
    <dbReference type="eggNOG" id="COG3022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061989_0_0_6"/>
    <dbReference type="OMA" id="WKNGQYK"/>
    <dbReference type="OrthoDB" id="1361974at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00652">
        <property type="entry name" value="UPF0246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005583">
        <property type="entry name" value="YaaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30283">
        <property type="entry name" value="PTHR30283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03883">
        <property type="entry name" value="H2O2_YaaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000131145" description="UPF0246 protein Swoo_1284">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00652"/>
        </source>
    </evidence>
    <sequence length="256" mass="28727" checksum="21BF53F05652177B" modified="2008-04-29" version="1">MLVLVSPAKTLDYDNPAATTEYTLPKLTQYSEQLIEECRKLTPADIASLMKVSDKIAGLNAARFESWSPRFTTGNAKQAVYAFRGDVYTGLDADSLSEDSLSRAQSQLRILSGLYGLLKPLDLMQPYRLEMGTRLANAKGTNLYQFWGDVITDEVNASLKEQGDELLVNLASNEYFKAVKPKLVNGTIITPVFKDRKNGQYKVISFFAKKARGMMVRYILDNKVSNLEELNKFDMAGYYYCEAESTAASPVFKREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIX4</accession>
    <name>B1KIX4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323968.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1330"/>
    <dbReference type="EnsemblBacteria" id="ACA85622">
        <property type="protein sequence ID" value="ACA85622"/>
        <property type="gene ID" value="Swoo_1330"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1330"/>
    <dbReference type="eggNOG" id="COG0762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089905_1_0_6"/>
    <dbReference type="OMA" id="MIDFSPM"/>
    <dbReference type="OrthoDB" id="1692876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="PTHR33219"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="182" mass="20170" checksum="AC2F2DA3070D985A" modified="2008-04-29" version="1">MNALSFLVSTIFDLYLMVVILRIWLQLAKADFYNPFSQFIVKATHPIVAPMRRVLPSIGAFDTASVVLALLVVTAKFVVLSLIAGAAINIPTILLIAVVSVFKQAGVLLFWMLIIRAILSWVSQGHNPIEMVMGQLTEPLLSPIRRILPPMGGLDLSLLIMMILLNFINILLAQYVPFWANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIZ8</accession>
    <name>B1KIZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323992.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85646">
        <property type="protein sequence ID" value="ACA85646"/>
        <property type="gene ID" value="Swoo_1354"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1354"/>
    <dbReference type="eggNOG" id="ENOG5033HG5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_194519_0_0_6"/>
    <dbReference type="OMA" id="GCADIKE"/>
    <dbReference type="OrthoDB" id="2057836at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766682" evidence="1">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="71" mass="7571" checksum="FD59B495267303CA" modified="2008-04-29" version="1" precursor="true">MKKLLNLTIAFAFIINLSACAELKETGRAIGQGTKEVTTDIGHATRDATKAIGHASRDAVKSVNDDLSKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ24</accession>
    <name>B1KJ24_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2768</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325380.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2768"/>
    <dbReference type="EnsemblBacteria" id="ACA87044">
        <property type="protein sequence ID" value="ACA87044"/>
        <property type="gene ID" value="Swoo_2768"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2768"/>
    <dbReference type="eggNOG" id="COG3102">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122770_0_0_6"/>
    <dbReference type="OMA" id="SFAQADH"/>
    <dbReference type="OrthoDB" id="1257033at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010393">
        <property type="entry name" value="DUF991"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37519">
        <property type="entry name" value="PTHR37519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06185">
        <property type="entry name" value="YecM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21018" checksum="B4B5F28D0B9F5F5A" modified="2008-04-29" version="1">MNNSLTLADLHSSWPDFTHNINLFLEELGLDQLSLECDHAALRVNSTSVADELSNALCNDGVVISNNMINGRPILIIELNTPLQLTNLTIDCIELPYPGSKQYPIEGWEHIELVLPCQANNCEQLTQALVERVPHLADVIDNKTETKVKLSSPSGEYERLANPTIAFKKGNICIKVHPHGIKEVIASEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA3</accession>
    <name>B1KJA3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_4322</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4322"/>
    <dbReference type="EnsemblBacteria" id="ACA88575">
        <property type="protein sequence ID" value="ACA88575"/>
        <property type="gene ID" value="Swoo_4322"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4322"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_146_0_6"/>
    <dbReference type="OMA" id="QPKRMVG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="468"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="537"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="593"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="669"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="740"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="980"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1123"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="1029"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="1172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA88575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1245" mass="141858" checksum="96C2EDAC55F39044" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI2</accession>
    <name>B1KJI2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ordered locus">Swoo_4402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326980.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4402"/>
    <dbReference type="EnsemblBacteria" id="ACA88654">
        <property type="protein sequence ID" value="ACA88654"/>
        <property type="gene ID" value="Swoo_4402"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4402"/>
    <dbReference type="eggNOG" id="COG1077">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052037_0_0_6"/>
    <dbReference type="OMA" id="MVICIPS"/>
    <dbReference type="OrthoDB" id="410781at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="217"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="297"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="349" mass="37166" checksum="9D1465EB0DC8CE77" modified="2008-04-29" version="1">MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLDEPSVVAIRGERGSGGQKSVAAVGTEAKQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSVFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGRNLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALIRDLDRLLMQETGIPVMVADDPLTCVARGGGKALEMIDMHGGDLFSEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJI8</accession>
    <name>B1KJI8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324007.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1369"/>
    <dbReference type="EnsemblBacteria" id="ACA85661">
        <property type="protein sequence ID" value="ACA85661"/>
        <property type="gene ID" value="Swoo_1369"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1369"/>
    <dbReference type="eggNOG" id="COG2315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105851_1_1_6"/>
    <dbReference type="OMA" id="NKRHWNT"/>
    <dbReference type="OrthoDB" id="1817663at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35145">
        <property type="entry name" value="PTHR35145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="128" mass="14496" checksum="31C2B3BA0C02B580" modified="2008-04-29" version="1">MDVETAKQYLLSKPETILDFPFGKEVSVFKVKGKMFATLAIGKMGKGDEDGHRDWWMNLKCDPDEAAILRDIFPAVIPGYHMNKALWNTVILDGSIPQGEIERMIDNSFSLVVAKMTKKDQRSILLHL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJK0</accession>
    <name>NRDR_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nrdR</name>
        <name type="ordered locus">Swoo_1381</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324019.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJK0"/>
    <dbReference type="SMR" id="B1KJK0"/>
    <dbReference type="STRING" id="392500.Swoo_1381"/>
    <dbReference type="EnsemblBacteria" id="ACA85673">
        <property type="protein sequence ID" value="ACA85673"/>
        <property type="gene ID" value="Swoo_1381"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1381"/>
    <dbReference type="eggNOG" id="COG1327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108412_0_0_6"/>
    <dbReference type="OMA" id="YRFTTYE"/>
    <dbReference type="OrthoDB" id="1551627at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_1000124549" description="Transcriptional repressor NrdR">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-cone" evidence="1">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <sequence length="149" mass="17041" checksum="ED9500E9E65B7487" modified="2008-04-29" version="1">MHCPFCSATDTKVIDSRLVADGHQVRRRRECAECHERFTTFEGAELVMPRVVKQDGSRQPFDEEKLRGGMLRAVEKRPVSMDQIEQALTKIKSTLRGTGEREIKSEMIGNLMMEQLVNLDKVAYIRFASVYRAFEDVSEFGDAIAKLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJR0</accession>
    <name>B1KJR0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Potassium efflux system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1441</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324079.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1441"/>
    <dbReference type="EnsemblBacteria" id="ACA85733">
        <property type="protein sequence ID" value="ACA85733"/>
        <property type="gene ID" value="Swoo_1441"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1441"/>
    <dbReference type="eggNOG" id="COG0475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005126_9_3_6"/>
    <dbReference type="OMA" id="PYLWFAK"/>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004771">
        <property type="entry name" value="K/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00932">
        <property type="entry name" value="2a37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="9">
        <location>
            <begin position="421"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="613"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA85733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="644" mass="70543" checksum="AC2E35E7F2C1BA63" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJU1</accession>
    <name>B1KJU1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325464.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2853"/>
    <dbReference type="EnsemblBacteria" id="ACA87128">
        <property type="protein sequence ID" value="ACA87128"/>
        <property type="gene ID" value="Swoo_2853"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2853"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056342_2_0_6"/>
    <dbReference type="OMA" id="KYVVYSH"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766726" evidence="1">
        <location>
            <begin position="27"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="46"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="35205" checksum="0E75769609FD1934" modified="2008-04-29" version="1" precursor="true">MANKTSLFLVLTAMMLQFTFSYQVTAQEQVSKVVDDVYRYGDPNLGYFSMFIITNDGVIVIDPMNTTHSQGLLKAIQKITKQPIRYLLHSHNHWDHAKGGQIFREQGAKIAAHKEAAQWMQKNPHGDLVMPDEIWSGKRKEIELGDKKIELHYLGINHGLGMTAFLLPKEKVAYIADIVTPKRMPFSIADFNIKELMRTLDELEQLDFTKAVFSHSYAKEAVGGKSDLADTKTFFIDLQQAIFAEFKKGTTFYQMPNTLKLPQYQQWAFYNEWLPINTWNMMFQVEMGSFPWRVESNSIEEKSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJU3</accession>
    <name>B1KJU3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325466.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2855"/>
    <dbReference type="EnsemblBacteria" id="ACA87130">
        <property type="protein sequence ID" value="ACA87130"/>
        <property type="gene ID" value="Swoo_2855"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2855"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_28_6"/>
    <dbReference type="OMA" id="QCRIANN"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="123"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="283"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="415" mass="47351" checksum="15BA30379F2A167D" modified="2008-04-29" version="1">MRILVVEDSRVVSRILQHLIAQELGCDVDFAEDMATARLLLTQYKYFVAITDLNLPDAQEGEIVKLVQGHQTPCIVLTGSLDGQQRKRLLQLGIVDYILKENRFSYEYVVRLVTRLKRNEKVKVLVADDSMVSRKFVRSLLEQQLFQVIEADDGLSALEILKSQPDITLLITDYNMPGLDGFGLILKVRESFTREELAIIGLSSDDDESLSARFIKNGANDFLQKPFVHEEFHCRVLNTLDSLDMIRKLWEQANLDYLTGVYNRRYFFNLFEEQLQQIEQKKTSLTLALLDIDFFKKVNDTYGHDIGDEVLVEFAARLKHFFGQHFTVARFGGEEFTVAFRGLNEDKVFSLMDKFRAQLEVEAIQTSQGPINVTVSTGIAGLSDESLDNLLQRADKALYDAKELGRNLVCIEGNE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-26" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJU9</accession>
    <name>NUOB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit B</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoB</name>
        <name type="ordered locus">Swoo_2861</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325472.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJU9"/>
    <dbReference type="SMR" id="B1KJU9"/>
    <dbReference type="STRING" id="392500.Swoo_2861"/>
    <dbReference type="EnsemblBacteria" id="ACA87136">
        <property type="protein sequence ID" value="ACA87136"/>
        <property type="gene ID" value="Swoo_2861"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2861"/>
    <dbReference type="eggNOG" id="COG0377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055737_7_3_6"/>
    <dbReference type="OMA" id="RENTANV"/>
    <dbReference type="OrthoDB" id="1904620at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000376374" description="NADH-quinone oxidoreductase subunit B">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01356"/>
        </source>
    </evidence>
    <sequence length="213" mass="24134" checksum="A20A9288EB3B7A93" modified="2008-04-29" version="1">MRWQLSKPEIIPTSTQTMQEVVEKNLLVTRLEDLVAWGRSNSLWPFNFGLSCCYVEMATSFTSRHDIARFGSEVIRATPREADLIVISGTVFLKMAPVIKHLYDQMLEPKWVICMGSCANSGGMYDVYSVVQGADRFLPIDLYVPGCPPRPEALMYGLTLLQEAIKDGAPRQARPLNRTITPEEIQAFACRNMRDEKHEQRIKADKLTPPDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW1</accession>
    <name>B1KJW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-methyltransferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2873</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325484.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2873"/>
    <dbReference type="EnsemblBacteria" id="ACA87148">
        <property type="protein sequence ID" value="ACA87148"/>
        <property type="gene ID" value="Swoo_2873"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2873"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_3_0_6"/>
    <dbReference type="OMA" id="WPTIYEG"/>
    <dbReference type="OrthoDB" id="1213908at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="O_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_2" evidence="3">
        <location>
            <begin position="183"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="360" mass="40630" checksum="D19C6E9887E82D70" modified="2008-04-29" version="1">MAFYQSPMKISAFDAKFEAQKIAFAPISFQVARCLLKFGILEQIDTSAEQGCSLDDIEKKTELSQYAISVLIDMGLSMGLLWQKEDRYLLDKIGHFLVEDDMAKVNLNFVHDVCYQGMFELEASLVEGKPKGLKVFGDWNTIYPTLSELPDQVKKSWFEFDHYYSDHAFGQLLPLIFQAKPAHIVDVGGNTGKWALACTAYDSNVKVTIMDLPGQLKVALKNAEEKGVADRVSGFQCDLLKESQEFCPNGDLYWMSQFLDCFSKEQILSILTRTAQSMSANSELCILETYWDRQPFEAGAYCVNATSIYFTAMANGDSRMYHSKEMLTLISQAGLYVDEDIDEIGLGHTLLRCKRKPTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW4</accession>
    <name>B1KJW4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C4-dicarboxylate anaerobic carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2876</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2876"/>
    <dbReference type="EnsemblBacteria" id="ACA87151">
        <property type="protein sequence ID" value="ACA87151"/>
        <property type="gene ID" value="Swoo_2876"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2876"/>
    <dbReference type="eggNOG" id="COG1288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035307_0_0_6"/>
    <dbReference type="OMA" id="GTRELKW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="513" mass="54932" checksum="003B5574F2597DEE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ2</accession>
    <name>B1KJZ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325515.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2906"/>
    <dbReference type="EnsemblBacteria" id="ACA87179">
        <property type="protein sequence ID" value="ACA87179"/>
        <property type="gene ID" value="Swoo_2906"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2906"/>
    <dbReference type="eggNOG" id="COG1621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_794309_0_0_6"/>
    <dbReference type="OMA" id="VKRIWEQ"/>
    <dbReference type="OrthoDB" id="1293876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="303" mass="34737" checksum="F5670E64AD4C0EB7" modified="2008-04-29" version="1">MKLISVDKIWDRADHNAFTDMVRFGDHLYCVFREATAHVSDDGALRVIRSADEGKSWESVVLMQMSHADLRDGKLISYKGELLLLGLGSFISRVKQERQSYLWRSQEGLTWSDPIEVAKPNDWLWRLVEHKGVLWGISYFPKPKGYASLYRSPDGHSFTRVFKKFNKQGYVNESGLFFDENNCAHCLLRRDPVWGPEETALLGFSKPPYQYWRWKELDKRIGGPVSFYYQGHHYGVVRLYDNKIRTSIAEINSVTGEVNELLSLPSGGDNSYAGVVLDRGSLKVSYYSSHEGKTAIYFAEVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ4</accession>
    <name>B1KJZ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Segregation and condensation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2908</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325517.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2908"/>
    <dbReference type="EnsemblBacteria" id="ACA87181">
        <property type="protein sequence ID" value="ACA87181"/>
        <property type="gene ID" value="Swoo_2908"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2908"/>
    <dbReference type="eggNOG" id="COG1386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045647_5_2_6"/>
    <dbReference type="OMA" id="HHTASGY"/>
    <dbReference type="OrthoDB" id="1771906at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019345">
        <property type="entry name" value="ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25079" checksum="3C954F35D851F729" modified="2008-04-29" version="1">MSKSKLLQINPDQLKQLIEAALFVMGKTVTIKGLRETVLVNFNVSRAKVKLAIEELQEDYQGRGVELVAVAGGYRFQTVEALSPYLQCMWQEKAPKYSRATLETLAVIAYRQPVTRGDIEFVRGVAVSSHTIKTLSDRHWIRAVGHKEVPGRPALYGTTAEFLAYFGLDTLADLPPLSDPESLAALFSNAESSNVPVSEDETVNIEHLADETEPTETQNREESTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK20</accession>
    <name>B1KK20_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Catalytic domain of components of various dehydrogenase complexes</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325543.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2934"/>
    <dbReference type="EnsemblBacteria" id="ACA87207">
        <property type="protein sequence ID" value="ACA87207"/>
        <property type="gene ID" value="Swoo_2934"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2934"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_2_1_6"/>
    <dbReference type="OMA" id="CIAKAIR"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-oxoacid_dh" evidence="1">
        <location>
            <begin position="9"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="228" mass="25083" checksum="4B26CB4844F37FA8" modified="2008-04-29" version="1">MENTLSNLVHLKGVRGAIAKKMIHSLHNSAQLSFHAEANISPLLNCKRQLSEQGNNVSLQDMLHLVIIATLGRHMHLNGKLENNTITYDPDIHLSFAVSLEDNLLVTPTIFSAQHLTITELQQLRHEATKKAQQNELKPKDYTGGSITITNLGLSRVKYFTPILNTPQIAILGLGATTESYKLNAKGELEATKLMGLSLTVDHRAIDGVPAANFLSDLCTNIEEIECE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD3</accession>
    <name>B1KKD3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324119.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1485"/>
    <dbReference type="EnsemblBacteria" id="ACA85773">
        <property type="protein sequence ID" value="ACA85773"/>
        <property type="gene ID" value="Swoo_1485"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1485"/>
    <dbReference type="HOGENOM" id="CLU_2107362_0_0_6"/>
    <dbReference type="OMA" id="NANYFRI"/>
    <dbReference type="OrthoDB" id="2169295at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766758" evidence="1">
        <location>
            <begin position="28"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12483" checksum="95901D8161CB882D" modified="2008-04-29" version="1" precursor="true">MKLSMLSSKVMVLSLLMLSLFSQQVFAENQAGKVGRINLYGGDWGNGWRGGMLYKLDTMPAGISYFTVRASDIAFDQFYALLLAAKHAKSTVTVTYNAGAQDANGYVTTLAITDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKU6</accession>
    <name>B1KKU6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327078.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88752">
        <property type="protein sequence ID" value="ACA88752"/>
        <property type="gene ID" value="Swoo_4501"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4501"/>
    <dbReference type="eggNOG" id="ENOG5031GNN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1383147_0_0_6"/>
    <dbReference type="OMA" id="NITYNFH"/>
    <dbReference type="OrthoDB" id="1594933at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="196" mass="21366" checksum="CE203D722492042E" modified="2008-04-29" version="1">MFSDLMRDKVTVLKLNGEKYEDIQASVQSKKTFIQRSDILIETGDLIQRKMSNDGIETYEVIDPGFHEGGSIIPAGYQIKHKNLGLPEAEKAVQSITYNLNGPNSRVNNHSTDNSTNVVNENSAVAEHIELLRSEINRLVQSTQEKQDALEVVDAIEGQFSSDKPSKAVVNTLISSLPHAGSIASIGSFLVSVLAG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL05</accession>
    <name>Y4561_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName>UPF0758 protein Swoo_4561</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_4561</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0758 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327136.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL05"/>
    <dbReference type="SMR" id="B1KL05"/>
    <dbReference type="STRING" id="392500.Swoo_4561"/>
    <dbReference type="EnsemblBacteria" id="ACA88811">
        <property type="protein sequence ID" value="ACA88811"/>
        <property type="gene ID" value="Swoo_4561"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4561"/>
    <dbReference type="eggNOG" id="COG2003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073529_0_1_6"/>
    <dbReference type="OMA" id="AMPDYEL"/>
    <dbReference type="OrthoDB" id="1833204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000089846" description="UPF0758 protein Swoo_4561">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="MPN" evidence="1">
        <location>
            <begin position="102"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="JAMM motif" evidence="1">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="225" mass="24916" checksum="5A304D982B433C22" modified="2008-04-29" version="1">MGIKDWPDGEGPRDRLIKFGVSQLSDAEVLAVLLRNGSQGLNAVELARNLINEFGGLREVLAASQSQVCRLSGMGPVKFAQLRAAVELSSRVSAQNLKRGKILSDPDLTRDYLMRQLRDRAYEVFAILLLDSQHRVIQFVELFRGTIDSASVYPRDVVSLVLEKKAAAVIVCHNHPSGVAEPSHADRRITERLKCALSTIDVSLLDHMVVGDREIVSFAERGWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL10</accession>
    <name>B1KL10_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="6">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GTP cyclohydrolase I</fullName>
            <shortName evidence="6">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">folE</name>
        <name evidence="8" type="ordered locus">Swoo_4566</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327141.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4566"/>
    <dbReference type="EnsemblBacteria" id="ACA88816">
        <property type="protein sequence ID" value="ACA88816"/>
        <property type="gene ID" value="Swoo_4566"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4566"/>
    <dbReference type="eggNOG" id="COG0302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_3_2_6"/>
    <dbReference type="OMA" id="CEHMCMS"/>
    <dbReference type="OrthoDB" id="1632367at2"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="7">
        <location>
            <begin position="42"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="24467" checksum="B4EC81441377B1EE" modified="2008-04-29" version="1">MTSKEAILSESAQLVQAALLERGLETPMLPSEFSAEDRKVKIEQHMREILTLMSLDLTDDSLADTPKRIAKMYVDEIFSGLDYANFPKITVIENKMGFDEMVKVNDISLTSTCEHHLVTIDGLARVAYLPRKNIIGLSKINRIVRFFAQRPQVQERLTQQVLVALQTLLETKDVAVKMDAVHYCVKSRGVMDSTSSTTTTALGGIFKSNPATRAEFLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ1</accession>
    <name>B1KLQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MotA/TolQ/ExbB proton channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3077</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3077"/>
    <dbReference type="EnsemblBacteria" id="ACA87348">
        <property type="protein sequence ID" value="ACA87348"/>
        <property type="gene ID" value="Swoo_3077"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3077"/>
    <dbReference type="eggNOG" id="COG0811">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053325_7_0_6"/>
    <dbReference type="OMA" id="REAWVSQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="63"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="175" mass="19616" checksum="1F6C67BD9EFAAD80" modified="2008-04-29" version="1">MMLYLMDIWDSVRGFMATGGDVLWLVAAVLFLMWVLMLERFWYLNLIAPKAHKSIITAWNDREDSTSWYAHRIREAWVSQAKQDMNARMLIIKTLVAACPMIGLLGTVTGMIQVFDVMAVHGTSNARMMAAGISMATMPTMAGMVAALSGVFFSTRLDAKMKISLEKLKDSLPHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM42</accession>
    <name>B1KM42_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0154</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322804.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0154"/>
    <dbReference type="EnsemblBacteria" id="ACA84455">
        <property type="protein sequence ID" value="ACA84455"/>
        <property type="gene ID" value="Swoo_0154"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0154"/>
    <dbReference type="eggNOG" id="COG1368">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014653_3_1_6"/>
    <dbReference type="OMA" id="TQAMMKG"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012160">
        <property type="entry name" value="LtaS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005091">
        <property type="entry name" value="Mmb_sulf_HI1246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="7">
        <location>
            <begin position="285"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="505"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="656" mass="73693" checksum="F59B52365B6879EB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM53</accession>
    <name>B1KM53_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CheW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322815.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0165"/>
    <dbReference type="EnsemblBacteria" id="ACA84466">
        <property type="protein sequence ID" value="ACA84466"/>
        <property type="gene ID" value="Swoo_0165"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0165"/>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048995_1_1_6"/>
    <dbReference type="OMA" id="CVNIMSV"/>
    <dbReference type="OrthoDB" id="1711729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20009" checksum="0E1884159CF76550" modified="2008-04-29" version="1">MTQITQQEQAIADDISQQYLTFIMASEEYGVDILSVQEIRGWEATTIIPNSPSHVKGVINLRGTIVPIIDLRQRFGIETLEYGATTVVIVVKVAIASDHKVIGIVVDAVSDVFSVNHGDVRNAPDFGDETDLGFIKGLTNTEDKMVILLDINKLLGSEILPEASQLSNLIHNIDAQQPQAVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM75</accession>
    <name>B1KM75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0187</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the globin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322837.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0187"/>
    <dbReference type="EnsemblBacteria" id="ACA84488">
        <property type="protein sequence ID" value="ACA84488"/>
        <property type="gene ID" value="Swoo_0187"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0187"/>
    <dbReference type="eggNOG" id="COG1017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_13_3_6"/>
    <dbReference type="OMA" id="MQRGWET"/>
    <dbReference type="OrthoDB" id="2026549at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="3">
        <location>
            <begin position="29"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15400" checksum="7119FDEA0E0BCE85" modified="2008-04-29" version="1">MALTQRQIQLVQHSFSLVEPISEQAADLFYDSLFKIDPSLKPLFRNNIKVQGRKLVAMLKAAVDGLDDLNTLVPVLQQLAQRHNAYGVKKSHFTPVGNALLYTLKTGLGSEYTDEVRQAWIIVIHIVADTMKPEIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM83</accession>
    <name>B1KM83_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c-type protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_0195</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="9">Binds 4 heme groups per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Binds 4 heme groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NapC/NirT/NrfH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322845.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0195"/>
    <dbReference type="EnsemblBacteria" id="ACA84496">
        <property type="protein sequence ID" value="ACA84496"/>
        <property type="gene ID" value="Swoo_0195"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0195"/>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096753_1_0_6"/>
    <dbReference type="OMA" id="TSTDEFC"/>
    <dbReference type="OrthoDB" id="1683334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019333">
        <property type="term" value="P:denitrification pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024717">
        <property type="entry name" value="NapC/NirT/NrfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000013">
        <property type="entry name" value="4_hem_cytochrm_NapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_NNT" evidence="12">
        <location>
            <begin position="9"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>a menaquinol</name>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>a menaquinol</name>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000013-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000013-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA84496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="21135" checksum="C8798FC0D3493B5F" modified="2008-04-29" version="1" precursor="true">MNLRALFKPSAKYSIFALLVVGIVVGVVGYFATQQTLHATSTDEFCMSCHSNHSLKDEVLASAHGGGSAGVTVQCQDCHLPHNPVKYLVKKIIVSKDLYGYLTIDGFNTQEWLDENRKEQADLALKYFKDTDSANCQHCHTRIYENQPETMKKMAKRMHERNFQKEPDKRKTCVDCHKGVAHVYPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG1</accession>
    <name>B1KMG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324305.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85959">
        <property type="protein sequence ID" value="ACA85959"/>
        <property type="gene ID" value="Swoo_1674"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1674"/>
    <dbReference type="HOGENOM" id="CLU_803848_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="345" mass="38577" checksum="1950916F39CA237C" modified="2008-04-29" version="1">MFTLKAILATVLISVVINGMLYFFQDERKVTNKLQLFHEGKDEFTALAVGTSHSIGFHFPSLGQKGINFYDGGGDIEEVVFKSGIIMDQAVNIGSIFVSVSPGTLHMSQNYGNNINRQLVVIKNLPLSYDVLLSTPSIVLPSLLEFLFPILEVKNEIKEKIDLSLASSKNLNGFSTDINRACLKPILTEVDKDALILGGYKLVTLLPNCLDSYAANTVTSHSSHIESTILSDVNMPSINVSRLSGMADEFKLRKVETRLILVVPPLTVEYYEDERIQKWISEHNKLLAELSKHPNIDVYDFHDFFHDEMADGSNDFFYDDDHLALPGAIKFSKALKQAMDEREGR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMY8</accession>
    <name>RS12_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpsL</name>
        <name type="ordered locus">Swoo_4695</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327264.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMY8"/>
    <dbReference type="SMR" id="B1KMY8"/>
    <dbReference type="STRING" id="392500.Swoo_4695"/>
    <dbReference type="EnsemblBacteria" id="ACA88945">
        <property type="protein sequence ID" value="ACA88945"/>
        <property type="gene ID" value="Swoo_4695"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4695"/>
    <dbReference type="eggNOG" id="COG0048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104295_1_2_6"/>
    <dbReference type="OMA" id="SPALEKC"/>
    <dbReference type="OrthoDB" id="1707228at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000123518" description="30S ribosomal protein S12">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-methylthioaspartic acid" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <sequence length="124" mass="13648" checksum="D77301D038E9EFE7" modified="2008-04-29" version="1">MATVNQLVRKPRAPKVDKTNVPALNACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCAGVSERRQGRSKYGAKRPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNC5</accession>
    <name>B1KNC5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_0321</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322971.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0321"/>
    <dbReference type="EnsemblBacteria" id="ACA84622">
        <property type="protein sequence ID" value="ACA84622"/>
        <property type="gene ID" value="Swoo_0321"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0321"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_0_1_6"/>
    <dbReference type="OMA" id="HMVGDRM"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="8"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="347"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="182"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="319"/>
            <end position="322"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="45"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA84622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="476" mass="50762" checksum="4A900A85F38C8E36" modified="2008-04-29" version="1">MSNEIKTQVVVLGAGPAGYSAAFRAADLGLDTVIIERFSTLGGVCLNVGCIPSKALLHVSKVIEEAKTISSHGVVFGEPQIDLDKLREYKKSVIGQLTGGLGGMSKMRKVDVVNGLGKFTGPNTIEVAGEDGVKVVHFENAIIAAGSRPIQLPFIPHEDPRVWDSTDALELKEVPGKLLVMGGGIIGLEMGTVYSSLGSEIDVVEMFDQVIPAADKDVVRVFTKKIKKKFNLMLETKVTAVEAKDDGIYVTMEGKKAPTEAVRYDAVLVAIGRVPNGKGLDAEKAGVNVDERGFINVDKQMRTNVPHIYAIGDIVGQPMLAHKGVHEGHVAAEVISGLKHFFDPKVIPSIAYTDPEVAWVGLTEKEAKEQGIAYETATFPWAASGRAIASDCADGMTKLIFDKETHRVIGGAIVGVNGGELLGEIGLAIEMDCDAEDLALTIHAHPTLHESVGLAAEIYEGSITDLPNPKAKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNJ4</accession>
    <name>B1KNJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324417.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1787"/>
    <dbReference type="EnsemblBacteria" id="ACA86071">
        <property type="protein sequence ID" value="ACA86071"/>
        <property type="gene ID" value="Swoo_1787"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1787"/>
    <dbReference type="eggNOG" id="COG3767">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128743_0_0_6"/>
    <dbReference type="OMA" id="KKEGKCG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765077" evidence="2">
        <location>
            <begin position="24"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="14333" checksum="AAE2EF3EA1406F09" modified="2008-04-29" version="1" precursor="true">MNLVKKTVVAAALGTVVVGSAFAAEAQANPFGYSQMESGYQLVDGEGKCGEGKCGGDKKKAKEGKCGEGKCGGDMKKAKEGKCGEGKCGGDMKKAKEGKCGEGKCGGDMKKAKEGKCGEGKCGGDKKKGKEGKCGEGKCGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNK6</accession>
    <name>B1KNK6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Guanosine-inosine kinase</fullName>
            <ecNumber evidence="2">2.7.1.73</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gsk</name>
        <name evidence="5" type="ordered locus">Swoo_1799</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + guanosine = ADP + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27710"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16750"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.73"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + inosine = ADP + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:21140"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.73"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; GMP biosynthesis via salvage pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from inosine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.73" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324429.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1799"/>
    <dbReference type="EnsemblBacteria" id="ACA86083">
        <property type="protein sequence ID" value="ACA86083"/>
        <property type="gene ID" value="Swoo_1799"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1799"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060237_0_0_6"/>
    <dbReference type="OMA" id="LLGVMCN"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00647"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00909"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106366">
        <property type="term" value="F:guanosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008906">
        <property type="term" value="F:inosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02246">
        <property type="entry name" value="Gua_Ino_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046405">
        <property type="entry name" value="IngK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="4">
        <location>
            <begin position="134"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="418"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="40"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="93"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="284"/>
            <end position="289"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="434" mass="48137" checksum="362C147A3111B0AD" modified="2008-04-29" version="1">MKFPGQRKSKHYFPVQNRDPLLAQLTQQPERFPTYITGIDQTLVDIEAKVADELLQRYELPKGNSTLIDDETAHALYTELKSQALISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKNIEVGSYAYRYLCNTSSKVDLNYLQPVEGPIGRCFTLISECGERTFAISKGSMDKLSPEFINKEVIQGASALVLTAYLMRASDGDQITQAALKAIEYAKEADVPVVLTLGTRFLIESDPQWWKTFIEENVTILAMNEDEGEALTGFKDPLQASEAALELCDLVLTTAGPLGLYMAGYTDDSEKRETSHTLLPGIIPEFNRYEFSRPKLKSDCNTPIKVYAHISPYMGGPEKIRNTNGAGDGALAALLHDLASNTFHKANVPGSSKHKRDGLCYSSFSQVCKYANRVAYEVLAQHSPRLSSGLPEREDSLEEAYWER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNT4</accession>
    <name>B1KNT4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane chaperone Skp (OmpH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3272</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the skp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3272"/>
    <dbReference type="EnsemblBacteria" id="ACA87542">
        <property type="protein sequence ID" value="ACA87542"/>
        <property type="gene ID" value="Swoo_3272"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3272"/>
    <dbReference type="eggNOG" id="COG2825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101388_2_1_6"/>
    <dbReference type="OMA" id="EKEQYDM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002094">
        <property type="entry name" value="OMP26_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766905" evidence="3">
        <location>
            <begin position="23"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR002094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="166" mass="18802" checksum="0783ABC179061AE1" modified="2008-04-29" version="1" precursor="true">MKMFNRAMTVLVLLAAPLAAQAEKIAVVDMQAVFEQLPQREQVSKTLKTEFGDRVASVQKMQEDLRGMLEKQQRDGALMSETQKTEMVRKMESMKSELQLKGKALDEDMRRRQGEEQNKLLVKVQQAINKIAEKESYDMVLQRGAVIYVKPTADISNKVVDALSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU6</accession>
    <name>B1KNU6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.117</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tetrahydrodipicolinate N-succinyltransferase</fullName>
            <shortName evidence="9">THDP succinyltransferase</shortName>
            <shortName evidence="9">THP succinyltransferase</shortName>
            <shortName evidence="9">Tetrahydropicolinate succinylase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapD</name>
        <name evidence="11" type="ordered locus">Swoo_3284</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA</text>
            <dbReference type="Rhea" id="RHEA:17325"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15685"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="EC" id="2.3.1.117"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.117" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325890.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3284"/>
    <dbReference type="EnsemblBacteria" id="ACA87554">
        <property type="protein sequence ID" value="ACA87554"/>
        <property type="gene ID" value="Swoo_3284"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3284"/>
    <dbReference type="eggNOG" id="COG2171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050859_0_1_6"/>
    <dbReference type="OMA" id="YFPIQKM"/>
    <dbReference type="OrthoDB" id="752123at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008666">
        <property type="term" value="F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.166.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00811">
        <property type="entry name" value="DapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005664">
        <property type="entry name" value="DapD_Trfase_Hexpep_rpt_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023180">
        <property type="entry name" value="THP_succinylTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037133">
        <property type="entry name" value="THP_succinylTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14805">
        <property type="entry name" value="THDPS_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00965">
        <property type="entry name" value="dapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THDPS_N_2" evidence="10">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="274" mass="29760" checksum="C4D9D89C10B2F337" modified="2008-04-29" version="1">MEALRQRIEAAFEVRAEISPSTVEPSVRADVEKAINMLDTGEARVAEKIDGQWHVHQWLKKAVLLSFRIFDNAVIDGAETKYFDKVPMKFADYDEARFREEAIRVVPPAAVRKGSFIGKNTVLMPSYVNLGAYVDEGSMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTRIFDRETGEIHYGRVPAGSVVVSGTLPSKCGTYNLYAAIIVKKVDAKTRAKVGINELLRIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNY5</accession>
    <name>B1KNY5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4767</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327333.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4767"/>
    <dbReference type="EnsemblBacteria" id="ACA89016">
        <property type="protein sequence ID" value="ACA89016"/>
        <property type="gene ID" value="Swoo_4767"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4767"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="ARPVYMS"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="389"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="854"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="880"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="910"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="959"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="986"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA89016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1037" mass="112539" checksum="CECC138D600FB658" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP77</accession>
    <name>B1KP77_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ordered locus">Swoo_0346</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322996.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0346"/>
    <dbReference type="EnsemblBacteria" id="ACA84647">
        <property type="protein sequence ID" value="ACA84647"/>
        <property type="gene ID" value="Swoo_0346"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0346"/>
    <dbReference type="eggNOG" id="COG0036">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054856_2_1_6"/>
    <dbReference type="OMA" id="WLQVDGG"/>
    <dbReference type="OrthoDB" id="1697639at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="144"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="177"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="199"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA84647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="24320" checksum="2B6EB29D600A3DE1" modified="2008-04-29" version="1">MRPFLIAPSILSADFARLGEDVDAVLNAGADVVHFDVMDNHYVPNLTIGPMVCQALRDYGVTADIDVHLMVKPVDRIIPDFAKAGASIITFHPEASEHLDRSLQLIKESGCKAGLVFNPATPLHYLDHVMDKLDVILLMSVNPGFGGQSFIPSTLDKLRQVRKLIDDSGYDIRLEVDGGVKVDNIAEIAAAGADMFVAGSAIFNKPDYKAVIDEMRSELASIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPB8</accession>
    <name>B1KPB8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323037.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84688">
        <property type="protein sequence ID" value="ACA84688"/>
        <property type="gene ID" value="Swoo_0389"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0389"/>
    <dbReference type="HOGENOM" id="CLU_134282_0_0_6"/>
    <dbReference type="OrthoDB" id="1846838at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="139" mass="15856" checksum="124024729210F352" modified="2008-04-29" version="1">MNIELYGYSLEVDVKKTKRTYESIQSSGCEECGCLYCQNFQKSIPECFPKELLDFFEKSCIDLIKDAEVYHYTDVSDDILNYGGEFYLWGKVLKHPSGEPELANNFTFSFTEPSPLAQEAFKGSGAICFSFSGDIKWLM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD1</accession>
    <name>ZAPB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division protein ZapB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">zapB</name>
        <name type="ordered locus">Swoo_0402</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the septum at mid-cell, in a FtsZ-like pattern.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323050.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KPD1"/>
    <dbReference type="SMR" id="B1KPD1"/>
    <dbReference type="STRING" id="392500.Swoo_0402"/>
    <dbReference type="EnsemblBacteria" id="ACA84701">
        <property type="protein sequence ID" value="ACA84701"/>
        <property type="gene ID" value="Swoo_0402"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0402"/>
    <dbReference type="eggNOG" id="COG3074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171174_1_0_6"/>
    <dbReference type="OMA" id="VQSAQHG"/>
    <dbReference type="OrthoDB" id="2065751at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01196">
        <property type="entry name" value="ZapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009252">
        <property type="entry name" value="Cell_div_ZapB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06005">
        <property type="entry name" value="ZapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0175">Coiled coil</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0717">Septation</keyword>
    <feature type="chain" id="PRO_1000138452" description="Cell division protein ZapB">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01196"/>
        </source>
    </evidence>
    <sequence length="67" mass="7614" checksum="BE8E1B4CCF90BD33" modified="2008-04-29" version="1">MSLELLSKLETKIQTALETIELLKMELEEEKQKSIGLAEQNQQLSQDLNSWNEKVTGLVGLLNEEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPJ9</accession>
    <name>B1KPJ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324498.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1868"/>
    <dbReference type="EnsemblBacteria" id="ACA86152">
        <property type="protein sequence ID" value="ACA86152"/>
        <property type="gene ID" value="Swoo_1868"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1868"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046586_2_3_6"/>
    <dbReference type="OMA" id="QLFDVQL"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="55"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="29094" checksum="E1FECD1D89FC9C09" modified="2008-04-29" version="1">MKPEVVIDGVNKISDTNIVAERFSAAAKTYSRHNCLQKRSAQGLLKEMSPCGVLLDIGCGPGTDFSHFKRVVEVISLDIAPGMLEQLSINFPSYTTICADAKAIPLPENSVDTVYSNLALQWCDDLQQSFKSTGAALKSGGDYYLSVVAEGSLPELVELGFRVNSFRSMTDIVSQFDPEFWLVKSAKLEPITVYFDDLKSLLYSIKGVGASIVSDEKSSEQNLSHGIRGREDWKERLARAECIRQAKGLPLTYHIAQLHVERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPL7</accession>
    <name>B1KPL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor plug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1886</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324516.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1886"/>
    <dbReference type="EnsemblBacteria" id="ACA86170">
        <property type="protein sequence ID" value="ACA86170"/>
        <property type="gene ID" value="Swoo_1886"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1886"/>
    <dbReference type="eggNOG" id="COG4773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_15_2_6"/>
    <dbReference type="OMA" id="YRFSDGH"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767278" evidence="6">
        <location>
            <begin position="31"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="58"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="262"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="729" mass="81709" checksum="CB351737074314BE" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT4</accession>
    <name>B1KPT4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">MEP cytidylyltransferase</fullName>
            <shortName evidence="3">MCT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ispD</name>
        <name evidence="4" type="ordered locus">Swoo_3348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325952.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3348"/>
    <dbReference type="EnsemblBacteria" id="ACA87617">
        <property type="protein sequence ID" value="ACA87617"/>
        <property type="gene ID" value="Swoo_3348"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3348"/>
    <dbReference type="eggNOG" id="COG1211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061281_3_1_6"/>
    <dbReference type="OMA" id="ERQHSVY"/>
    <dbReference type="OrthoDB" id="1836139at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00108">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 3 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="3">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="3">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="24713" checksum="5293E0257CF9108B" modified="2008-04-29" version="1">MNDPQDKVVALVPAAGIGSRMGSEIPKQYLEINGVPILNITLTVLLTHPKIDVVIVALHPEDTLFHTLSQSSNPKLRTVVGGGERADSVLACLGEVEDNVWALVHDAARPCLSHEDIDKLLASRLEFPQGAILAAPVRDTMKRSNTGGTIVQTVCREQLWHALTPQLFLGSALRDNLASALRQGVTVTDEASAMEWAGNAPGLVSGNVKNIKITHPDDLKLAKLFLADEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPU8</accession>
    <name>B1KPU8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325966.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3362"/>
    <dbReference type="EnsemblBacteria" id="ACA87631">
        <property type="protein sequence ID" value="ACA87631"/>
        <property type="gene ID" value="Swoo_3362"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3362"/>
    <dbReference type="eggNOG" id="ENOG50332XE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190006_0_0_6"/>
    <dbReference type="OMA" id="SERGCVM"/>
    <dbReference type="OrthoDB" id="2015921at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="9096" checksum="C5257AAFB1F9D79C" modified="2008-04-29" version="1">MSSSDNRNGVGRVILVLMAGSLLSLSGCSNYDPVPVEKCSEVVKHAQKVLGSMAPDGKTMMADCKAASDSERGCVMAATKKGALAQCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC7</accession>
    <name>B1KQC7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenylate cyclase</fullName>
            <ecNumber evidence="4">4.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP pyrophosphate-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Adenylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_0484</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the adenylyl cyclase class-1 family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323131.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0484"/>
    <dbReference type="EnsemblBacteria" id="ACA84782">
        <property type="protein sequence ID" value="ACA84782"/>
        <property type="gene ID" value="Swoo_0484"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0484"/>
    <dbReference type="eggNOG" id="COG3072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013280_0_0_6"/>
    <dbReference type="OMA" id="YDDYVMS"/>
    <dbReference type="OrthoDB" id="1153472at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000274">
        <property type="entry name" value="Adenylate_cyclase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024686">
        <property type="entry name" value="Adenylate_cyclase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024685">
        <property type="entry name" value="Adenylate_cyclase_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38760">
        <property type="entry name" value="PTHR38760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12633">
        <property type="entry name" value="Adenyl_cycl_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01295">
        <property type="entry name" value="Adenylate_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001444">
        <property type="entry name" value="Adenylate_cycl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01092">
        <property type="entry name" value="ADENYLATE_CYCLASE_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenyl_cycl_N" evidence="14">
        <location>
            <begin position="8"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA84782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="807" mass="93025" checksum="26D138DD2F9D524E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD0</accession>
    <name>DAPF_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Diaminopimelate epimerase</fullName>
            <shortName evidence="1">DAP epimerase</shortName>
            <ecNumber evidence="1">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dapF</name>
        <name type="ordered locus">Swoo_0487</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323134.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQD0"/>
    <dbReference type="SMR" id="B1KQD0"/>
    <dbReference type="STRING" id="392500.Swoo_0487"/>
    <dbReference type="EnsemblBacteria" id="ACA84785">
        <property type="protein sequence ID" value="ACA84785"/>
        <property type="gene ID" value="Swoo_0487"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0487"/>
    <dbReference type="eggNOG" id="COG0253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053306_1_1_6"/>
    <dbReference type="OMA" id="HVAMRVH"/>
    <dbReference type="OrthoDB" id="1921631at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0457">Lysine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000099267" description="Diaminopimelate epimerase">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="1">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="1">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="site" description="Important for dimerization" evidence="1">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <sequence length="279" mass="30626" checksum="2D865DEF34E6E969" modified="2008-04-29" version="1">MIHFAKMHGLGNDFMVVDGVTQNVFFSPEQIKRLADRNFGVGFDQLLLVEPPYDPDLDFHYRIFNADGGEVEQCGNGARCFARFVRNKGLTNKHKIKVSTSNGKITLRLERDGNVTVNMGVPVLDPSKIPFNAKRVEKTYLLQTSSSHAMETFLCGAISMGNPHCVLEVEDIEHAEVERIGALLTQNERFPKGVNVGFMQVIDAGHIKLRVYERGAAETLACGTGACAAAAVGQLQGKLNKMVRVDLPGGTLTINWEGEGNPLWMTGPAEHVYDGQIPQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE8</accession>
    <name>PRMA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="1">L11 Mtase</shortName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prmA</name>
        <name type="ordered locus">Swoo_0506</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323151.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQE8"/>
    <dbReference type="SMR" id="B1KQE8"/>
    <dbReference type="STRING" id="392500.Swoo_0506"/>
    <dbReference type="EnsemblBacteria" id="ACA84803">
        <property type="protein sequence ID" value="ACA84803"/>
        <property type="gene ID" value="Swoo_0506"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0506"/>
    <dbReference type="eggNOG" id="COG2264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049382_4_1_6"/>
    <dbReference type="OMA" id="EFFFIFP"/>
    <dbReference type="OrthoDB" id="1712450at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00406">
        <property type="entry name" value="prmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000132827" description="Ribosomal protein L11 methyltransferase">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <sequence length="293" mass="32784" checksum="2CC793DC2607B081" modified="2008-04-29" version="1">MPWIQLKIDTDNQHADTLSDLLMEEGSLSITLEDGKDTPIFEPTLGETPLWNHTVLTALFEADRDLSIVVDNLKLQPFLGADFSYKIEQVEDKDWEREWMDNFHPIKFGERLWICPSWREIPDPEAVNIILDPGLAFGTGTHPTTALCLEWLDSLNFDNKEVIDFGCGSGILAVAALKLGATKVTGIDIDYQAIDASKANAERNGVEDQLTLYLPEDQPENLKADILVANILAGPLRELAPLIAEKVKPGGQLALSGLLQEQALEVAEFYTQWFDMDEPAHKEEWSRLTGIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQL7</accession>
    <name>B1KQL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase, N-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1972"/>
    <dbReference type="EnsemblBacteria" id="ACA86256">
        <property type="protein sequence ID" value="ACA86256"/>
        <property type="gene ID" value="Swoo_1972"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1972"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090620_0_0_6"/>
    <dbReference type="OMA" id="HLDRFKY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="28"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="112"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="244" mass="28501" checksum="54060E5DCC850A8D" modified="2008-04-29" version="1">MFPTSRLFFNIKSHNIGSNDPIHKEIMTLATLYSFRRCPYAMRARLGIYLSGNQVMLREIILKDKPQAMLDVSPKGTVPVLITSTQQVIDESLDIMQWALSQNDPHNMLLQGNLEQQKVAMALIKTNDENFKPWLDRYKYADRYPEFSDTYYREKGEQFISQLEKLLTQGDNLLGHNESIADHAIYPFVRQFAHVDKVWFEQAPYPNLHRWLANHLNSDAFTAIMKKYPLWLDNEQEYLFGAGH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQY9</accession>
    <name>GRPE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">grpE</name>
        <name type="ordered locus">Swoo_3479</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326079.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQY9"/>
    <dbReference type="SMR" id="B1KQY9"/>
    <dbReference type="STRING" id="392500.Swoo_3479"/>
    <dbReference type="EnsemblBacteria" id="ACA87745">
        <property type="protein sequence ID" value="ACA87745"/>
        <property type="gene ID" value="Swoo_3479"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3479"/>
    <dbReference type="eggNOG" id="COG0576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057217_6_0_6"/>
    <dbReference type="OMA" id="YAYEKIA"/>
    <dbReference type="OrthoDB" id="1906715at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_1000137628" description="Protein GrpE">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="209" mass="22982" checksum="E523BCF33863D944" modified="2008-04-29" version="1">MSNDSSKAKQNQVDEAVEGEILTESEVETGNDEASLMDELTQANFRVEELEQALAEANAKIEEQKDSVTRAAASEANIRRRAAQDVEKAHKFALEKFANELLPVIDNMERALQGTNAEAEETKAIYEGVELTLKSFVSTVDKFGLKEVNPHGESFNPEHHQAIGMQPSPEFPANTVMMVMQKGYILNDRLLRPAMVMVSQGGSGVDTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ8</accession>
    <name>B1KQZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326088.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3488"/>
    <dbReference type="EnsemblBacteria" id="ACA87754">
        <property type="protein sequence ID" value="ACA87754"/>
        <property type="gene ID" value="Swoo_3488"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3488"/>
    <dbReference type="eggNOG" id="ENOG503206C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_175662_0_0_6"/>
    <dbReference type="OMA" id="INIVIFC"/>
    <dbReference type="OrthoDB" id="2062876at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="107" mass="12043" checksum="B333A44D703DF999" modified="2008-04-29" version="1">MILIGATLVLVAFFFHLNRGEFIEKQAYFAIAFMALYIVVYLFVPSQLNGTSVRTGQLYEYIPLISLGAILFPHLNSKSPEGITQILGWLGLISVSIILCIFKIFVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ9</accession>
    <name>B1KQZ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326089.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87755">
        <property type="protein sequence ID" value="ACA87755"/>
        <property type="gene ID" value="Swoo_3489"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3489"/>
    <dbReference type="HOGENOM" id="CLU_172304_0_0_6"/>
    <dbReference type="OrthoDB" id="2170187at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9574" checksum="BE3294ADF34D8D5A" modified="2008-04-29" version="1">MAYKQPKPLFEWKIDESDKELYLASILDDETILSAYGRYAHSSGSKLVSWQEFLAGEMNELVEKTMGEEVLMELLTQLKNLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR16</accession>
    <name>B1KR16_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0537</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323181.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0537"/>
    <dbReference type="EnsemblBacteria" id="ACA84833">
        <property type="protein sequence ID" value="ACA84833"/>
        <property type="gene ID" value="Swoo_0537"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0537"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010403_0_0_6"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="562"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="836"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1056" mass="119284" checksum="170E716AD1BC1B46" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR32</accession>
    <name>B1KR32_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323197.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0553"/>
    <dbReference type="EnsemblBacteria" id="ACA84849">
        <property type="protein sequence ID" value="ACA84849"/>
        <property type="gene ID" value="Swoo_0553"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0553"/>
    <dbReference type="eggNOG" id="ENOG50321R5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120017_0_0_6"/>
    <dbReference type="OMA" id="TEIQDFD"/>
    <dbReference type="OrthoDB" id="1833932at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="157" mass="17138" checksum="82FA38CAF823774E" modified="2008-04-29" version="1" precursor="true">MKHSFRQFTHKIAIMMVAVVLLQFAGANLGAHQLHLGDHKEESVNHPHLEFTAQITSLAQCIDCTCNVETDVPLSPSSDANISQSLDLPGAKHNHLISKTETQTFDLCLDCQCHGGHVTAMSITTMVPSIPKGDELVASVEQYLPPEATLNYRPPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR39</accession>
    <name>B1KR39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase U6 penicillin-insensitive murein endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0560</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323204.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0560"/>
    <dbReference type="EnsemblBacteria" id="ACA84856">
        <property type="protein sequence ID" value="ACA84856"/>
        <property type="gene ID" value="Swoo_0560"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0560"/>
    <dbReference type="eggNOG" id="COG3770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052496_0_0_6"/>
    <dbReference type="OMA" id="VRPWWGH"/>
    <dbReference type="OrthoDB" id="1681877at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005073">
        <property type="entry name" value="Peptidase_M74"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03411">
        <property type="entry name" value="Peptidase_M74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018455">
        <property type="entry name" value="MepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767313" evidence="3">
        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="278" mass="30916" checksum="5BA41DB0F8AD3BA7" modified="2008-04-29" version="1" precursor="true">MAKYLLLLCVLYLILGFAASANPWARVEQPFTGSSDAIGSYSNGCLSGGVGLASEGEGFQVIRTSRKRYYGHADLVNFINEYAATLKQAGLDDLLIGDMSMPRGGHFTSGHRSHQIGLDVDIWLRQANRKLTAQEIENPKKLDVVNRKAFKVNANWSGAHGVMIRLAALDKRVARIFVHPVIKQQLCSQAEQGSSWLQKVRPWWGHSSHMHIRLKCPDNSQLCEGQDLPPEGDGCDELSWWQEQMSAPKKVNNSEKKPKPKPKKRKPMQCTPLLGSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR60</accession>
    <name>B1KR60_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323225.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0581"/>
    <dbReference type="EnsemblBacteria" id="ACA84877">
        <property type="protein sequence ID" value="ACA84877"/>
        <property type="gene ID" value="Swoo_0581"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0581"/>
    <dbReference type="HOGENOM" id="CLU_2289762_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="101" mass="11643" checksum="605FA7733D8E80C4" modified="2008-04-29" version="1">MTSSLCDKNYNLNNNMKKSKLPVGVDYIDGRYYVRLSESSQTYENCSFESPMLAFTYRRQKLNKVALESKKLKGHSTNSLNKLKKISLLSDEQIELILQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR77</accession>
    <name>B1KR77_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323242.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0598"/>
    <dbReference type="EnsemblBacteria" id="ACA84894">
        <property type="protein sequence ID" value="ACA84894"/>
        <property type="gene ID" value="Swoo_0598"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0598"/>
    <dbReference type="eggNOG" id="COG0659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032158_1_0_6"/>
    <dbReference type="OMA" id="AGMLCHW"/>
    <dbReference type="OrthoDB" id="1000375at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031563">
        <property type="entry name" value="MOT1/MOT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970">
        <property type="entry name" value="PTHR31970"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16983">
        <property type="entry name" value="MFS_MOT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="385" mass="40992" checksum="63CEAA3F6B50BE4F" modified="2008-04-29" version="1">MTCKSTFFSRCDQLSGELSGAFADLGTFLPLVLGLIALNHFSPQGIFLGFGLFALFTAFYYRRPIPVQPMKVIAALVIAQGLTPGMLQASGMMMGAILLLLAYSGAITWMAKQLSPAVSIGIQLAIGLQLIWMGGQMMSETWLIGISAFIALFASKFMPLRYLAMPLVLALGIIWQMNSGIAPSFDLTGHTSWQPSWPSLDEWTSAAGLLVLPQLALTLTNAVIAISAMAKDKFPADKVNGKENFTPKRLATSSGLANLLLAPFGATAMCHGAGGLAVQHHFGARTWIAPTIFGTACLLIAFSWGDGIATMLSLIPLAILGSMLAIAGTQLAWSKRLIDGKPFCIFVILSTAAICLVVNTAAGLAVGVILEMGRRQWKQVSSLRH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRS8</accession>
    <name>DAPB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="1">HTPA reductase</shortName>
            <ecNumber evidence="1">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dapB</name>
        <name type="ordered locus">Swoo_3579</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRS8"/>
    <dbReference type="SMR" id="B1KRS8"/>
    <dbReference type="STRING" id="392500.Swoo_3579"/>
    <dbReference type="EnsemblBacteria" id="ACA87843">
        <property type="protein sequence ID" value="ACA87843"/>
        <property type="gene ID" value="Swoo_3579"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3579"/>
    <dbReference type="eggNOG" id="COG0289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047479_2_1_6"/>
    <dbReference type="OMA" id="HHPNKAD"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword id="KW-0457">Lysine biosynthesis</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000202819" description="4-hydroxy-tetrahydrodipicolinate reductase">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="102"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="169"/>
            <end position="170"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="271" mass="29154" checksum="A448654783C21E06" modified="2008-04-29" version="1">MMSEKVRVAITGGSGRMGRTLIEAARQQPMIYLGAVIERAGSTLIGVDAGELAGVGSMNVPITDSLDLAVDDFDVLIDFTSPEASLVHTDWCAKHGKAIVIGTTGFNHSQKEQISAYAEKTPVVMAPNMAVGVNLLWKLLEVAAEVMGDYTDIEIIEGHHRYKKDAPSGTALKMGEVIAETLGRDLDKCAVYGREGITGERDRQTIGFSTIRAGDIVGEHTALFADIGERIEITHKASSRMTFANGAMRAASWLVEQDAGLYDMQQVLGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCW0</accession>
    <name>B1KCW0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Trk system potassium uptake protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_0034</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TrkH potassium transport family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322684.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0034"/>
    <dbReference type="EnsemblBacteria" id="ACA84335">
        <property type="protein sequence ID" value="ACA84335"/>
        <property type="gene ID" value="Swoo_0034"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0034"/>
    <dbReference type="eggNOG" id="COG0168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030708_0_1_6"/>
    <dbReference type="OMA" id="GSMNHFS"/>
    <dbReference type="OrthoDB" id="756220at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004772">
        <property type="entry name" value="TrkH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006247">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00933">
        <property type="entry name" value="2a38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4 9" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006247-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA84335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="480" mass="52903" checksum="466E52D2CC40EE9E" modified="2008-04-29" version="1" precursor="true">MLNLRPLLFILGIFLSTLTVFMFIPLIFALFYGEETVGAFMISSLFTGTCASACIHQGRSRNLHLNIRDMFLLTSLTWLIVSFFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLDSMDHSILIWRSLLQWMGGIGFIVMAVAVLPFLNVGGMRLFRTESSDWSDKAIPRTQDMAKHLFYIYILLTVLCGIAYHLSGMNWFQAINHAMTTLSTGGYSTSDSSMAAFSNQAHWVGVVFMAAGGLPLLMFVNSIQQRSLWVWNDAQVKGFILFISLVSMSLAFWLWLGHEMSPLDALRLASFNVVSVVTTTGYGLTDYTAWGALANIAFLFLMFAGSCSGSTSGGIKIFRFQIAGAIMREQLKQQFHPSGVFKERYNNRIISDDIVRSLVTFILLFAFVIVLLSIILVLTGLDPMTSFTGAITAVTNVGPGLGDVIGPAGNFSTLPDVAKWALAIGMLLGRLEILTVAVLFHPSFWKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCZ5</accession>
    <name>B1KCZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322673.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0023"/>
    <dbReference type="EnsemblBacteria" id="ACA84324">
        <property type="protein sequence ID" value="ACA84324"/>
        <property type="gene ID" value="Swoo_0023"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0023"/>
    <dbReference type="eggNOG" id="COG1739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083552_0_0_6"/>
    <dbReference type="OMA" id="VTVDHQR"/>
    <dbReference type="OrthoDB" id="1777855at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015796">
        <property type="entry name" value="Impact_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00257">
        <property type="entry name" value="IMPACT_YIGZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="19"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1949" evidence="3">
        <location>
            <begin position="142"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="211" mass="23337" checksum="0357CB4B1AC0D766" modified="2008-04-29" version="1">MTDSYRIPSAELIIEEEIKHSRFISFLFHCQSYEELKCALTNIKADYPGANHYCYAFVAAEPGNTLAMGSSDDGEPSGSAGRPMLATLQGADVGEIGAVVVRYFGGTKLGVGGLVRAYSSGIKQGLTQLETQLKQIRYPGLLVCDYNQLKDVEYLLAQYDGVIEERDFMEKVTLNFAIPKRFQTELNRDLATMSQGLLAAKFDFHKSDSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD60</accession>
    <name>B1KD60_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acyl-CoA reductase</fullName>
            <ecNumber evidence="7">1.2.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3633</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a long-chain fatty aldehyde + CoA + NADP(+) = a long-chain fatty acyl-CoA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="EC" id="1.2.1.50"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Lipid metabolism; fatty acid reduction for biolumincescence.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the LuxC family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.50" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326228.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3633"/>
    <dbReference type="EnsemblBacteria" id="ACA87895">
        <property type="protein sequence ID" value="ACA87895"/>
        <property type="gene ID" value="Swoo_3633"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3633"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_567216_0_0_6"/>
    <dbReference type="OMA" id="LRTMAEI"/>
    <dbReference type="OrthoDB" id="1776958at2"/>
    <dbReference type="UniPathway" id="UPA00569"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050062">
        <property type="term" value="F:long-chain-fatty-acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008218">
        <property type="term" value="P:bioluminescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07080">
        <property type="entry name" value="ALDH_Acyl-CoA-Red_LuxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008670">
        <property type="entry name" value="CoA_reduct_LuxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05893">
        <property type="entry name" value="LuxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009414">
        <property type="entry name" value="LuxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0455">Luminescence</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR009414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="479" mass="53924" checksum="096525B904189D8E" modified="2008-04-29" version="1">MKKYIPMIIGGVIQEEKLENNRELTLSSDNKVSLPILDKVLAEKVVAHTIDNKLTLNKIVNFLYTVGQRWKSEEYARRRTYIRDLQNFLGYSSEMAKLEANWIAMLLCSKSALYDIVSNDLSSQHIIDEWLPQGDCYVKALPKGRSVHLLAGNVPLSGITSILRAILTKNECVIKTSSTDPFTATALVSSFIDVDSEHTITRSMSVMYWSHNEEISLPLKIMNSADVVIAWGGDDAIKWAIKHTPPHANILKFGPKKSLTVIDNPKDLTAAAIGVAHDICFYDQQACFSTQSVYYIGEQLASFIHELEKQLTIYSKILPKGTQTFDEKAAFSLTDKECLFSGFQVNKGENQSWLIINSSLNNVGNQPLSRSVYIHQASDIKEVLPFVNKGATQTVSIFPWKSSFKYRDQLAEHGAERIVESGMNNIFRVGGSHDGMRPLQHLVNYISQERPSSYTTKDVAVEIEQTRYLEEDKFLVFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDQ7</accession>
    <name>B1KDQ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324798.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2171"/>
    <dbReference type="EnsemblBacteria" id="ACA86454">
        <property type="protein sequence ID" value="ACA86454"/>
        <property type="gene ID" value="Swoo_2171"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2171"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031275_8_0_6"/>
    <dbReference type="OMA" id="WRTLTAY"/>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="366" mass="40353" checksum="AD61F3A19C1C0B42" modified="2008-04-29" version="1">MLALLTNWYKERFSDPQAVTLVFILLGIALAIYFAGGLLAPLIVALILAFLLEWPVAQMLKIGINRTTAASLVLVVFIGVMLLITLGLVPSIWKQGVALITDLPTMLDKGLLTAQTYVNQYPQFVSPEQLDSMVAELKKMLDTQHLLDIGKQILGYSASLLVLMVYAILVPLLVFFFLKDKDQLIKGSKRFIPTNRELARKVWFEMDQQIFNYIRGKVIEIVIIGVVSYLFFAIMDMRYAALLGVLTGFSVLIPYVGATLVTLPIALVAFFQWGFSPEFGYLMLGYGIIQALDGNLLVPLLFSDAVDLHPVFIIAAVLIFGGLWGVWGVFFAIPLASLVKAVINAWPTPNSLSDGASVDEQSAEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDS0</accession>
    <name>B1KDS0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324811.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2185"/>
    <dbReference type="EnsemblBacteria" id="ACA86467">
        <property type="protein sequence ID" value="ACA86467"/>
        <property type="gene ID" value="Swoo_2185"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2185"/>
    <dbReference type="eggNOG" id="COG0288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053879_3_1_6"/>
    <dbReference type="OMA" id="PANEIIG"/>
    <dbReference type="OrthoDB" id="1841447at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="23216" checksum="5CFA402331F9B0B2" modified="2008-04-29" version="1">MKILKPLFDNNRRWAERIVQEKPHFFEQLATQQNPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSVLQYAVEVLKVKHIMVVGHYGCGGVKASMGTERLGLIDNWLGHIRDIHRLHSDELDKLEGEEKFDRLCELNVIEQVGNVSSTNIVQDAWARGQNVSVHGWIYGIDNGLLSDLDVTVDNEQFKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDS1</accession>
    <name>B1KDS1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324812.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2186"/>
    <dbReference type="ESTHER" id="shewm-b1kds1">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86468">
        <property type="protein sequence ID" value="ACA86468"/>
        <property type="gene ID" value="Swoo_2186"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2186"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_6"/>
    <dbReference type="OMA" id="ESYLMHD"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="29"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="276" mass="31053" checksum="D21A79F56EC59EFE" modified="2008-04-29" version="1">MKFTSYKNRLTIEDKTLSYIDIGTGPVLLLGHSYLWDAQMWAPQIEALSQQYRCIVPDLWGHGDSDPLPDNCRSLQHIADHMLKLMDQLDIQEFSIIGLSVGGMWGAELALKVPKRVKSLAMLGCFVGFEPEVARAKYYTMLDAIKEAQAVPEALVEQIAPLFFAHNTEANNPELFNGFKESLRQVKPEQIDTICRLGKIIFGRRDTLEEIESLNAPCLIMTGVEDTVRPVLEGYLMHDAIKGSEFIHIPQAGHISTLEQAEFVNQHLCAFLSQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE68</accession>
    <name>B1KE68_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0759</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323401.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0759"/>
    <dbReference type="EnsemblBacteria" id="ACA85054">
        <property type="protein sequence ID" value="ACA85054"/>
        <property type="gene ID" value="Swoo_0759"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0759"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_1_1_6"/>
    <dbReference type="OMA" id="PGDSYAQ"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="63"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="4">
        <location>
            <begin position="211"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="483" mass="54235" checksum="A09DA05092EF89DE" modified="2008-04-29" version="1" precursor="true">MNNLWRWSLPLNKYLLFGLTALLSNQSHGHELAQMAAPLYSLEQTISYRELDNGLQLRLLPIPSSRSVSIATQFSIGSRDEIVGQTGYAHLFEHMLFKGSENAPGDSYAQTMSALSGQFNASTFFDFTNYYLTLPSEALELALWLEADRFIRPNLTPETVKNQQATVLEEMATTIDNQAYVRDAMEFLLTQAKGTPYGHSVIGSKEDVSKATVKQLTLFHQHHYRPDAAQISIVGGYTQETNSWIDSAFGQWQPLSQPPEKTAADSQAAIKLENRYVHGEIIDDRGPWPALLLAWHTVGQQDKDAEAVTLLEAYLFQNRASLIKQSGLTDPEQLLTYSIPLSMELMGVSNLVVVPRARASLDQLTKNVQQMISNIAKQGIDSASLEQLKANWLNQSLRRLDQPSRLARHLSATQARDKLVPLTGPWERINAVTNEQIQAVANTYFNQGYVRLDLLPPWYIRWTKALLEFLPESVSNSLEESVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEE0</accession>
    <name>B1KEE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase IS200-family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0470</name>
        <name evidence="3" type="ordered locus">Swoo_1034</name>
        <name evidence="4" type="ordered locus">Swoo_2237</name>
        <name evidence="5" type="ordered locus">Swoo_2564</name>
        <name evidence="6" type="ordered locus">Swoo_2692</name>
        <name evidence="7" type="ordered locus">Swoo_2737</name>
        <name evidence="8" type="ordered locus">Swoo_3775</name>
        <name evidence="9" type="ordered locus">Swoo_3987</name>
    </gene>
    <organism evidence="4 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908</strain>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323117.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84768">
        <property type="protein sequence ID" value="ACA84768"/>
        <property type="gene ID" value="Swoo_0470"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85327">
        <property type="protein sequence ID" value="ACA85327"/>
        <property type="gene ID" value="Swoo_1034"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86518">
        <property type="protein sequence ID" value="ACA86518"/>
        <property type="gene ID" value="Swoo_2237"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86841">
        <property type="protein sequence ID" value="ACA86841"/>
        <property type="gene ID" value="Swoo_2564"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86968">
        <property type="protein sequence ID" value="ACA86968"/>
        <property type="gene ID" value="Swoo_2692"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87013">
        <property type="protein sequence ID" value="ACA87013"/>
        <property type="gene ID" value="Swoo_2737"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88034">
        <property type="protein sequence ID" value="ACA88034"/>
        <property type="gene ID" value="Swoo_3775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88244">
        <property type="protein sequence ID" value="ACA88244"/>
        <property type="gene ID" value="Swoo_3987"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0470"/>
    <dbReference type="KEGG" id="swd:Swoo_1034"/>
    <dbReference type="KEGG" id="swd:Swoo_2237"/>
    <dbReference type="KEGG" id="swd:Swoo_2564"/>
    <dbReference type="KEGG" id="swd:Swoo_2692"/>
    <dbReference type="KEGG" id="swd:Swoo_2737"/>
    <dbReference type="KEGG" id="swd:Swoo_3775"/>
    <dbReference type="KEGG" id="swd:Swoo_3987"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101320_0_1_6"/>
    <dbReference type="OMA" id="DKAFWQP"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="11"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="144" mass="17374" checksum="2122F8DDD96B72A6" modified="2008-04-29" version="1">MSRYEKASHVYWRCQYHIVWTPKYRFRILKNKLGKDVYRCIHVYSEQLGCVVVELNVQIDHVHLVIKVPPKLSISKLMGALKGKIALKMFSKYPYLRKNKLWGNHFWQRGYFVDTVGINEEVIRRYVRHQEKVEKQEQPQLDLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEH1</accession>
    <name>EFP_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor P</fullName>
            <shortName evidence="1">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">efp</name>
        <name type="ordered locus">Swoo_2268</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the elongation factor P family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324892.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KEH1"/>
    <dbReference type="SMR" id="B1KEH1"/>
    <dbReference type="STRING" id="392500.Swoo_2268"/>
    <dbReference type="PRIDE" id="B1KEH1"/>
    <dbReference type="EnsemblBacteria" id="ACA86549">
        <property type="protein sequence ID" value="ACA86549"/>
        <property type="gene ID" value="Swoo_2268"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2268"/>
    <dbReference type="eggNOG" id="COG0231">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074944_2_1_6"/>
    <dbReference type="OMA" id="WSVVEFQ"/>
    <dbReference type="OrthoDB" id="1260763at2"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000096205" description="Elongation factor P">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <sequence length="186" mass="20569" checksum="B6F8E87D83F4230B" modified="2008-04-29" version="1">MKTAHEIRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKMKLKNVLLDSSTETTFKGEDKMDDIILERLDCTYSYFADPMYVFMDAEYNQYDVEAGNLGDASAYIVDGMEEVCQVTFYEGKAISVELPTTIVREVTYTEPSARGDTSGKVMKPATVSGGATLSVADFVKTGDMIEIDTRTGEFKKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEM2</accession>
    <name>B1KEM2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Two component, sigma54 specific, transcriptional regulator, Fis family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3778</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326368.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3778"/>
    <dbReference type="EnsemblBacteria" id="ACA88037">
        <property type="protein sequence ID" value="ACA88037"/>
        <property type="gene ID" value="Swoo_3778"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3778"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_6_6"/>
    <dbReference type="OMA" id="AIRMVEM"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="152"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="460" mass="51557" checksum="D49E6D580B592DFC" modified="2008-04-29" version="1">MKLARNILLVDDEASWLRTLALTLNRLVPEAQVDTCIDSRQVIDRLSVEEYALVLLDLTMPFHSGETLLEMIRTSFPKTRVIIVTGVNEVDTAVRCIKNGAYDYFIKTDKVEDLARTVRRALEVVGLERNYLRIKERFLSRTLAQPEAFNNILTCEPVLLDQFRYLEAVAQSPEPILIQGESGTGKDEFAQSCHQLCCSKAPFININLAGLSTQAFELQLFGQIHTQEDGQISAQAGVLHQVGEGMLYLNEIAELPLEAQAKLVDVIEHKQYYPIGSDRSYPVKCKIITSTQNDLIALNKLGKFRSDLLYRLCSHKIKLPPLRERKLDHSMLINHFIDRAAKEMGLESPLQPTNLARQLADYDFPGNLHELKGMVFDSVSRSDGVQLNITPFMEAINEQRGGVGTSESKIVFPKTLPTLAEISNTLIQEAMSRTANNQTAAAQMLGISQSALSRRLTKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ8</accession>
    <name>B1KEQ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3814"/>
    <dbReference type="EnsemblBacteria" id="ACA88073">
        <property type="protein sequence ID" value="ACA88073"/>
        <property type="gene ID" value="Swoo_3814"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3814"/>
    <dbReference type="HOGENOM" id="CLU_3257795_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="42" mass="4769" checksum="E68516162F6D0A94" modified="2008-04-29" version="1">MNTNNKIELIEEALLENVSGGREEAFCIELCLEFCLSICFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF64</accession>
    <name>B1KF64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324947.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2326"/>
    <dbReference type="EnsemblBacteria" id="ACA86605">
        <property type="protein sequence ID" value="ACA86605"/>
        <property type="gene ID" value="Swoo_2326"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2326"/>
    <dbReference type="eggNOG" id="COG1942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168247_0_0_6"/>
    <dbReference type="OMA" id="WFDRGQE"/>
    <dbReference type="OrthoDB" id="1899588at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015017">
        <property type="entry name" value="DUF1904"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08921">
        <property type="entry name" value="DUF1904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="12655" checksum="E664911F58388624" modified="2008-04-29" version="1">MPHIRLRGLPEAAVIDLSRTLLHDLAKICNVNQQAFTLDWVSSVSYRDGMRELSTTQVEVLWFPKDPNTHQMVESAIREAIKIVYPELQNLSVIFIALDPSTYFRNGEHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF75</accession>
    <name>B1KF75_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324958.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2337"/>
    <dbReference type="EnsemblBacteria" id="ACA86616">
        <property type="protein sequence ID" value="ACA86616"/>
        <property type="gene ID" value="Swoo_2337"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2337"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_8_0_6"/>
    <dbReference type="OMA" id="EWRVMAV"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="18373" checksum="4F70D7EDE7911A64" modified="2008-04-29" version="1">MSQAKLAQTSISLNQFLPYRLVNLAQKVSVNFAEVYQSEFNLTTPEWRILVHLAEQTLCDKSDGSVRQQSTGISAKELTELASMDKSTVSRAVKLMLDKGYITKQVHIADKRAFTLTLTTAGFALYQTIAPKALAWEESLLKALDKQEYQALMQILDKLDSKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFA5</accession>
    <name>B1KFA5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative RNA polymerase, sigma 70 family subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2367"/>
    <dbReference type="EnsemblBacteria" id="ACA86646">
        <property type="protein sequence ID" value="ACA86646"/>
        <property type="gene ID" value="Swoo_2367"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2367"/>
    <dbReference type="eggNOG" id="COG4941">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035311_1_2_6"/>
    <dbReference type="OMA" id="RQSYGKL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="44822" checksum="DF9850EDBC6F4AE8" modified="2008-04-29" version="1">MRHIEMIEDAVQFALTTALDNWIREQIPKNPSAWLFRVASNKLVSELRSETRHNELLQDNLEQLSRRAAEPSQFHLPNELEDEMLRMLFICCDHKVPIESQLIFALKSLCGFSISEIAIRLFSSEANIYKRLSRARNTLKKISPPSFELSNSDYIKRLPSVTRILYLMFTEGHLSSNVDFAIRKDLCEEAIRLTLILVNHSVGDNPECHALLSLMFLNLSRMSAREDMSGALLLLEEQNRELWDRGCIEHGLYWLAKSADGQHFSRYHAEAGVAAEHCLASSYKKTNWERIVDCYLLLEQSAPSALHQLNRAIAIAEWKGPQAGLEVLQANTPPSWLASNYLWSAVLADLHLRAREYQLGEYYSIEAIHSAPSQQICDLLKRRFAKSRGEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFH7</accession>
    <name>B1KFH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326482.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88152">
        <property type="protein sequence ID" value="ACA88152"/>
        <property type="gene ID" value="Swoo_3894"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3894"/>
    <dbReference type="HOGENOM" id="CLU_1123906_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="247" mass="27988" checksum="0C63DC1C56E0DF11" modified="2008-04-29" version="1">MFLSELGVAVAIGTVIAIIFAAIDSLLLNRQVKWLNDKAATWYIFFDNLNIPDLATPFFKHSSRYANIFLYISVFLFSYFATTLIVNGVVLELLQMRTFESIDFFDTLLILLVGISSLIYYLAIKALQFIFLKGFFYIGITMLSITSYLFIGFAPEIALYFVETEGDYVSMALLIGILSLFLIPLFCYLAFIIALFSLLFSFRVFKKTTSHLFELSSERKTIFAHLGVFIGLLVALGKFIIELSNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFJ4</accession>
    <name>B1KFJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3911"/>
    <dbReference type="EnsemblBacteria" id="ACA88169">
        <property type="protein sequence ID" value="ACA88169"/>
        <property type="gene ID" value="Swoo_3911"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3911"/>
    <dbReference type="eggNOG" id="COG3746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043009_1_1_6"/>
    <dbReference type="OMA" id="QIFAANI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764808" evidence="1">
        <location>
            <begin position="42"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="396" mass="43964" checksum="E2028124470BE866" modified="2008-04-29" version="1" precursor="true">MDMIRAPNPMSGYEHENKKVKKLKLSILISALLGASTAVMADEFEPSVDLGGAVKVKYFVDDGNEASKSNGGTFAFDALELDIDSHISENWTASAKYVFKNSSSNHFIKYAFAAYNGVEDWQFQGGVISKPFGNKSFISHNWWESINYYMGFEDDYDLGAKAIYSSGNWTSEVAFFKNSEYSSSDTRGYAADAFTGSIGDNTYDNEETNTFNIRQSYVFDYDKLTVQVGASLEYGQLYNAAHDDHGTSTAYAVHLDAQYSGYQLQLQMVDYDYDQYDSENSNGLYAMKMGGGAYEVAAKGQIFAANIAKSIGYDWGTVTLYNDYSHLTPDTDINANLNDSVINTTGVSIGVSDFFIFVDHIYGKNAVWLGGQQGLGIENQDDNFYSLFNISVAYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN2</accession>
    <name>B1KFN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323545.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0904"/>
    <dbReference type="EnsemblBacteria" id="ACA85198">
        <property type="protein sequence ID" value="ACA85198"/>
        <property type="gene ID" value="Swoo_0904"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0904"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_0_5_6"/>
    <dbReference type="OMA" id="MTLHYPE"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="62"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="374" mass="41930" checksum="894A43745119A093" modified="2008-04-29" version="1" precursor="true">MNTIKLTVLSMILTFCINHHVFAHVENADKRKKLNPTVTQKVDYQSLIESMITDSPQPFSGTVLLMQKGKKLVSLSKGDGITQDSSFVLASLSKQITATLIMQAVESGRLTLDSHLNQYLSNDDEPKHSLDNKLPLSQGYHEGITIAQLLTHTSGINTQGKPNLFEPGTRFQYSNLGYTLLGQVLEKVNKLSFSEQISQFNKKYKLSGLDAKTGSIDNIRQHLPTLSLGLTETAKGLSQSDLTINTSLIPAGGIISTTRAFSDFQQKLHSGQLISPKSYQLMTTPHTEITFLWPNMHYGYGLRLNFDDNLTEYSHTGYLSGYMSMTLYYPQYNLSLVMLENLSLNLNYLDRVFELHNQIRAAIRQSLINRNSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN4</accession>
    <name>B1KFN4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0906</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323547.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0906"/>
    <dbReference type="EnsemblBacteria" id="ACA85200">
        <property type="protein sequence ID" value="ACA85200"/>
        <property type="gene ID" value="Swoo_0906"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0906"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_1_6"/>
    <dbReference type="OMA" id="IEIGRYR"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767320" evidence="6">
        <location>
            <begin position="26"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="45"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="393"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="875" mass="96218" checksum="3F60BEF43CD0F784" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS9</accession>
    <name>B1KFS9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PpiC-type peptidyl-prolyl cis-trans isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323592.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0952"/>
    <dbReference type="EnsemblBacteria" id="ACA85245">
        <property type="protein sequence ID" value="ACA85245"/>
        <property type="gene ID" value="Swoo_0952"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0952"/>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090028_6_1_6"/>
    <dbReference type="OMA" id="GPVRTQF"/>
    <dbReference type="OrthoDB" id="1838755at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="92" mass="10246" checksum="ABEE6CF39DE4F0FA" modified="2008-04-29" version="1">MARTASALHILVKHKELAEEIIQKLNKGAKFDQLAKKHSTCPSGKKGGSLGEFKKGQMVPAFDKVCFTGELITPHLVKTKFGWHVIKVLYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGD4</accession>
    <name>B1KGD4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326600.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4015"/>
    <dbReference type="EnsemblBacteria" id="ACA88271">
        <property type="protein sequence ID" value="ACA88271"/>
        <property type="gene ID" value="Swoo_4015"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4015"/>
    <dbReference type="eggNOG" id="ENOG5032Y7H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153072_1_0_6"/>
    <dbReference type="OMA" id="VSWLGFI"/>
    <dbReference type="OrthoDB" id="2012213at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021339">
        <property type="entry name" value="DUF2956"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11169">
        <property type="entry name" value="DUF2956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="112" mass="12477" checksum="9923DD276A253EEB" modified="2008-04-29" version="1">MVKKVAQKPSQKTVDEATQIARATQKPGQDKEQTKLIAKGIQNGIELYKKQQKAKARAASKAKKQSIKQKNNEENALPLEDIVNGNRAASNSLPWILLVISWLFFGAYIVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM1</accession>
    <name>B1KGM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMMECR1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323695.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1056"/>
    <dbReference type="EnsemblBacteria" id="ACA85349">
        <property type="protein sequence ID" value="ACA85349"/>
        <property type="gene ID" value="Swoo_1056"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1056"/>
    <dbReference type="eggNOG" id="COG2078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095686_0_0_6"/>
    <dbReference type="OMA" id="RGCIGFP"/>
    <dbReference type="OrthoDB" id="1812209at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027623">
        <property type="entry name" value="AmmeMemoSam_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="PTHR13016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="SSF143447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04335">
        <property type="entry name" value="AmmeMemoSam_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00296">
        <property type="entry name" value="TIGR00296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="12"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="203" mass="23045" checksum="8E75D13319DEBB0D" modified="2008-04-29" version="1">MPVSPSIELTFEEKSQLLRLSRDTLQQHFAPQTNPAASTDLVHELDLRASSILNKTLGCFVTLTLQGELRGCIGHIETPQRLHQTIPTLTLRSALHDPRFSPLTTELLELITIELSILSPLRSLTVNCREDLHHYLAQNRVGIVLTEDNKRGVFLPQVWQKMPTPKHFIDALLIKGHWPKNYWSEKIKIAQFSVCHFGGNSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGR5</accession>
    <name>B1KGR5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325125.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2507"/>
    <dbReference type="EnsemblBacteria" id="ACA86784">
        <property type="protein sequence ID" value="ACA86784"/>
        <property type="gene ID" value="Swoo_2507"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2507"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1057251_0_0_6"/>
    <dbReference type="OMA" id="IWIKANK"/>
    <dbReference type="OrthoDB" id="2177030at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="30388" checksum="6F0892DD85073115" modified="2008-04-29" version="1">MDIQMFRTYIKSRQTTLEAINEDPHSIKWVNSAPTIEKIKDIEKLFYEQVLSEKDYSSLIMLLRDKYFTEGAFNISLEQENSVQDLLKKRSEHLLKDSLIIDDDKSVEFDFILLGEKPAKLEILRCRKLERLSINRLLEGLVVMNSPKLTELYVPTENNLKYVDLYKCNKLLDFSFLRRLDSVLYLSVGGNSNLKNLDSLNDSSNVVILNLSESKLIKDSSTVNKLKKLKKLKYLTTAATQKELALLRTELPNCFVNGKKLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS3</accession>
    <name>B1KGS3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ImpA_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325133.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2515"/>
    <dbReference type="EnsemblBacteria" id="ACA86792">
        <property type="protein sequence ID" value="ACA86792"/>
        <property type="gene ID" value="Swoo_2515"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2515"/>
    <dbReference type="eggNOG" id="COG3515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_652036_0_0_6"/>
    <dbReference type="OrthoDB" id="994994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010657">
        <property type="entry name" value="ImpA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06812">
        <property type="entry name" value="ImpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="ImpA_N" evidence="4">
        <location>
            <begin position="19"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="401" mass="44688" checksum="1CE56BD5864C3F5C" modified="2008-04-29" version="1">MDNTSRKLDCFNLASELTELRNSAAYQQMRVEINRRNNPLSGGTDWEKVYQLALQISSGLGADLLTSAYFVTAASKTRGVSGLASGLDLMLSVVSFSTELAQLPSEKVSEIINWAVTKVTPEIKKMAVTSSNVRDWYRCEHACQKLFELITQKQPQQVPNLDVLGYLIFEKIDLLETNKVSVLPSSASNTVPVKVKARRWPLWALSSLIVICSLLSGYLAVLYHQEVSGKLPLWLYQAPEEKVAPESSIAQRIDRAFSLPQGEPLVSIYPEQVSLLVELDKNYQRFANARTIMANLSQLSQALPESSNKMKQETLSIAQYASSLSPILGRTYYIGDLLEDKEYARAEVELNQLNSQLKALLIKRTLLAQQLHNQQSDESGTLQLELSSQPSSDVISQDGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT8</accession>
    <name>B1KGT8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325148.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2530"/>
    <dbReference type="EnsemblBacteria" id="ACA86807">
        <property type="protein sequence ID" value="ACA86807"/>
        <property type="gene ID" value="Swoo_2530"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2530"/>
    <dbReference type="eggNOG" id="COG0045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007415_0_2_6"/>
    <dbReference type="OMA" id="SFMSQSG"/>
    <dbReference type="OrthoDB" id="445933at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="501"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="740"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="896" mass="97673" checksum="0723F28FD17DEADB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH38</accession>
    <name>B1KH38_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMI1_KNR4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326679.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4094"/>
    <dbReference type="EnsemblBacteria" id="ACA88350">
        <property type="protein sequence ID" value="ACA88350"/>
        <property type="gene ID" value="Swoo_4094"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4094"/>
    <dbReference type="HOGENOM" id="CLU_1474232_0_0_6"/>
    <dbReference type="OrthoDB" id="1820807at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="31"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="21554" checksum="21CE5EF029055671" modified="2008-04-29" version="1">MSKDISELCAKIKWKPIDTDYGATKESYLSSNEELIAIERFLQAKLPDDYLWFMKNVGRRLIDDRRINIKLNGVSLSFLDWFRDAIDVLTFTQMASEKEDKMQTSFNLVVISSSISHDEVLLDVSAGHYGNIWFKHHNPKWRQKFSENPEGLVLIANSFTDLFSKIVNNHSPGEIDFNFDDDDEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHA7</accession>
    <name>B1KHA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323761.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1122"/>
    <dbReference type="EnsemblBacteria" id="ACA85415">
        <property type="protein sequence ID" value="ACA85415"/>
        <property type="gene ID" value="Swoo_1122"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1122"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_4_2_6"/>
    <dbReference type="OMA" id="VNAQPWR"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="200" mass="22714" checksum="D469012D2C57EBD8" modified="2008-04-29" version="1">MEVFQAIKQRRAVKHYHADAEMPAEDFDKIMSAVILSPTSYNIQHWRFVRVTDKEQRNKVKSAAWGQAQVADASELVILCADINAWNDRPERYVINSPQETQDMLLPMMDAFYNGKEQIQRDEAMRSCGIAAQTMMLAAKELGYDTCPMVGFDREELARLIRLPQGYVIAMMIAIGTAEKSAHPRGGQLPLNEVLAENYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHG2</accession>
    <name>B1KHG2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323816.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85470">
        <property type="protein sequence ID" value="ACA85470"/>
        <property type="gene ID" value="Swoo_1177"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1177"/>
    <dbReference type="eggNOG" id="ENOG50331S8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_184537_0_0_6"/>
    <dbReference type="OMA" id="GDIFHEA"/>
    <dbReference type="OrthoDB" id="1934960at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="71" mass="8139" checksum="54E25C76B8F81F3E" modified="2008-04-29" version="1">MLKFDVFGKTMLVQRKEGAWLLFIDSGLGLRSRVFDVVIPTELTEQDLAGYLDDIFHEHSSEKHPHVIALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHK8</accession>
    <name>B1KHK8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325233.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2616"/>
    <dbReference type="EnsemblBacteria" id="ACA86893">
        <property type="protein sequence ID" value="ACA86893"/>
        <property type="gene ID" value="Swoo_2616"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2616"/>
    <dbReference type="eggNOG" id="ENOG502ZMUV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174679_0_0_6"/>
    <dbReference type="OMA" id="KAQMLKY"/>
    <dbReference type="OrthoDB" id="1893041at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="107" mass="12643" checksum="B59693CDCF5DADCD" modified="2008-04-29" version="1">MNNNFDLQSAIAALDEYGYDKKQSSDLTQARNKQQMSKYIESLDYNLRRLLILQETVNELVAKKKHLIAQQENIQTYKTKVINLSRQFNISYDEVLQIMQEQTNQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHS2</accession>
    <name>B1KHS2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4144</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326729.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4144"/>
    <dbReference type="EnsemblBacteria" id="ACA88400">
        <property type="protein sequence ID" value="ACA88400"/>
        <property type="gene ID" value="Swoo_4144"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4144"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_0_6"/>
    <dbReference type="OMA" id="IWVPLAC"/>
    <dbReference type="OrthoDB" id="1200399at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764891" evidence="2">
        <location>
            <begin position="21"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="365" mass="39979" checksum="AA0D725CF68293E3" modified="2008-04-29" version="1">MKHSQYLTLKLLFATLLLSACNNQPKLNTIADPVVTMMTINEVAPSPRMQFPAVAAAADRSELAFRVSGEITQINVKPGDMVKKDQVLASLDTTDYQLSLDDAKTRYKLAQSQFSRAAKLVKTGSLAKSQYDELKAQRDIAKADHDLAALKLSYTKLLAPFDGVVSRVPALAFEVVGVGQSIMNIHNISDVDIKIQAADIIYVNHSNRESEETLAEVDPRVVLDDGKEYRLTMKEFTVEPDPVSGAFMVTLTMPMPKDRIILDGMSVDVNASGEGLLAYNAGAMEIPIEAVFNADGDSLDASEQYVWLLDDENRVHKQKIEVEKLTPTGIRVTNGIAKGERLVTSGVNKLVDGQLVIIKGEENRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIH8</accession>
    <name>B1KIH8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sel1 domain protein repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326802.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4218"/>
    <dbReference type="EnsemblBacteria" id="ACA88474">
        <property type="protein sequence ID" value="ACA88474"/>
        <property type="gene ID" value="Swoo_4218"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4218"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079818_1_0_6"/>
    <dbReference type="OMA" id="GICVKAN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767088" evidence="1">
        <location>
            <begin position="33"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="25006" checksum="053DEE446D0583E8" modified="2008-04-29" version="1" precursor="true">MFLKASIGFIASLPRSASIMILMLLAPLSSQAEETQAVDIYSQEQLIELIRSKQYLTRVEGDDCQLVQDIEARAEVLKQPLYQYLWGEMLNYGICVKANPPRGMALLRDSVAQGSAEAMVRIAEYYYHGTFVFQDKERAVHYVLPAAASGDLPARMLLVRLFGEGYGSYRDFELGYHWLYNDVFSDEATKKEAYELLKVLEEKIPPSIVAKIKLQHLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIM9</accession>
    <name>B1KIM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326852.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4269"/>
    <dbReference type="EnsemblBacteria" id="ACA88525">
        <property type="protein sequence ID" value="ACA88525"/>
        <property type="gene ID" value="Swoo_4269"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4269"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_22_1_6"/>
    <dbReference type="OMA" id="NPARELY"/>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="145" mass="16925" checksum="D5FC7ACC0872816C" modified="2008-04-29" version="1">MDFEIVRAEQVDHDFLLQLRLSTMVEHLEQAGIFLTQDEHLTRLNDDFDCYHLVIHQNERVGALKYREMSDKFEIMQIQISPAHQGYGLGKMVLNQVIAWSVNRGKPIFLTVLKANPARELYLRLGFTIVGEDQDEFHMLRQLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIN2</accession>
    <name>B1KIN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized membrane-anchored protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326855.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4272"/>
    <dbReference type="EnsemblBacteria" id="ACA88528">
        <property type="protein sequence ID" value="ACA88528"/>
        <property type="gene ID" value="Swoo_4272"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4272"/>
    <dbReference type="eggNOG" id="COG4714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060300_0_0_6"/>
    <dbReference type="OMA" id="KLHWAKE"/>
    <dbReference type="OrthoDB" id="898513at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018682">
        <property type="entry name" value="DUF2167_membr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09935">
        <property type="entry name" value="DUF2167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764530" evidence="2">
        <location>
            <begin position="21"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="33143" checksum="8CF76649774D6A93" modified="2008-04-29" version="1" precursor="true">MKIKMILAICCLLLPWLSFAETSPELTEQEQYELWANTLWNSLDRQTGEIALKGNVAKLQVPDDFYYLNPADTEKVLVEIWGNPPGNPSLGMLFPADTTPFDAESWGVTIDYEQEGYVSDKDANDIDYNELLTQMKSDTRDNSNARVEQGYEPIELVGWAAAPFYNAETHKLYWAKEIKFGNADTNTLNYNIRVLGRKGVLVLNFIASMDQKAIIDSKLDNVLNIADFNEGSQYADFDPEIDEVAAYGLGALVAGKVVAKTGLIAGLIIFLKKFGIFIVLGIGALFKKLFSRKKSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ4</accession>
    <name>B1KIQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326877.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88550">
        <property type="protein sequence ID" value="ACA88550"/>
        <property type="gene ID" value="Swoo_4295"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4295"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098919_0_1_6"/>
    <dbReference type="OMA" id="GIPCESQ"/>
    <dbReference type="OrthoDB" id="1940131at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008613">
        <property type="entry name" value="Excalibur_Ca-bd_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05901">
        <property type="entry name" value="Excalibur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00894">
        <property type="entry name" value="Excalibur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="22872" checksum="34B30B163F6E35AB" modified="2008-04-29" version="1">MERGTLVRWNDEKGFGFIKPETGNGKDVFIHISALKHMARKPVIGDGILFLTEQQTDGKIKAIKANIEGVAVIASTSRHQARTTHNSRSHNSKSHNRHSRQSKSSSVILIPLLAILALGIYGYKRFEALTAQSNTQTHSTNEPSQQPAAKIEWIQPKETFHCEAGKLHCSQMRSCTEAKFYNRNCPGTKMDGDGDGIPCEIQHCGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ17</accession>
    <name>B1KJ17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325373.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2761"/>
    <dbReference type="EnsemblBacteria" id="ACA87037">
        <property type="protein sequence ID" value="ACA87037"/>
        <property type="gene ID" value="Swoo_2761"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2761"/>
    <dbReference type="eggNOG" id="ENOG502Z8W3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026769_0_1_6"/>
    <dbReference type="OMA" id="VVIQTFY"/>
    <dbReference type="OrthoDB" id="1250894at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011435">
        <property type="entry name" value="UmpAB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07556">
        <property type="entry name" value="DUF1538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="28316" checksum="7E49EE62B3E96CCC" modified="2008-04-29" version="1">MEMLKGLLDTLLLTARDVIPIAVILFGFQLGVLKRPIANWHKVVLGFFYVIVGLTLFLVGLELALFPIGETMAEQLTSVEFIHPNLGPDEAIIWQDYLWVYIFAAAIGFSTTIAEPSLIAVAIKANEVSAGAIGVQGLRISVAIGVSFGIALGCFRIVVGDPIHYYIMAGYIIVVIQTFYAPKMIIPLAYDSGGVTTSTVTVPLVAALGLGLATNVEGRNPLIDGFGLIAFASLFPMISVMGYAQIVELLDKRRSVKEQNNTP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJJ9</accession>
    <name>GLYA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="1">SHMT</shortName>
            <shortName evidence="1">Serine methylase</shortName>
            <ecNumber evidence="1">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glyA</name>
        <name type="ordered locus">Swoo_1380</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324018.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJJ9"/>
    <dbReference type="SMR" id="B1KJJ9"/>
    <dbReference type="STRING" id="392500.Swoo_1380"/>
    <dbReference type="EnsemblBacteria" id="ACA85672">
        <property type="protein sequence ID" value="ACA85672"/>
        <property type="gene ID" value="Swoo_1380"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1380"/>
    <dbReference type="eggNOG" id="COG0112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022477_2_1_6"/>
    <dbReference type="OMA" id="VTNRNAI"/>
    <dbReference type="OrthoDB" id="861782at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0554">One-carbon metabolism</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000091578" description="Serine hydroxymethyltransferase">
        <location>
            <begin position="1"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>(6S)-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>(6S)-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="356"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>(6S)-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
        </ligand>
    </feature>
    <feature type="site" description="Plays an important role in substrate specificity" evidence="1">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <sequence length="418" mass="45272" checksum="3F785E752794AA42" modified="2008-04-29" version="1">MLKKDMNIADFDPQLFQAIQDETRRQEEHIELIASENYTSPRVLEAQGSQLTNKYAEGYPGKRYYGGCEHVDIAEELAISRAKELFGATYANVQPHSGSQANAAVFMALLEGGDTVLGMSLAHGGHLTHGSHVSFSGKLYNSVQYGIDETTGKIDYAEVERLAVEHKPKMIIAGFSAYSGIIDWGKFREIADKVGAYLFVDMAHVAGLIAAGIYPNPLPHAHVVTTTTHKTLAGPRGGLILSAIDDEAIYKKLNSAVFPGGQGGPLMHVIAAKAVAFKEALEPEFTAYQEQVVVNAQAMAKTFIERGYDVVSGGTDNHLFLLDLISKDITGKDADAALGLANITVNKNSVPNDPRSPFVTSGLRIGSPAITRRGFKEAQAVELTNWMCDVLDDITNEGTIERVKNQVLELCAKFPVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM8</accession>
    <name>B1KJM8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324047.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1409"/>
    <dbReference type="EnsemblBacteria" id="ACA85701">
        <property type="protein sequence ID" value="ACA85701"/>
        <property type="gene ID" value="Swoo_1409"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1409"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_7_3_6"/>
    <dbReference type="OMA" id="FLVNMND"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15759" checksum="5FD55C5CD9413806" modified="2008-04-29" version="1">MKPNDKTRATLVAGKAKPRGSFPHLKRAGDFIYVSGTSSRLPDNSFAGVEVDEMGATNLDIEVQTRAVIDNIRDLLRSVDADLTDLVEISTFLVNMNDFAGYNRVYSEYFDYSGPTRTTVAVHQLPHPHLLIECKAVAYKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJS7</accession>
    <name>B1KJS7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4212 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2839</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325450.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2839"/>
    <dbReference type="EnsemblBacteria" id="ACA87114">
        <property type="protein sequence ID" value="ACA87114"/>
        <property type="gene ID" value="Swoo_2839"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2839"/>
    <dbReference type="eggNOG" id="COG4327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140854_4_1_6"/>
    <dbReference type="OMA" id="FYAWRMN"/>
    <dbReference type="OrthoDB" id="2029157at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019886">
        <property type="entry name" value="Na_symporter_ssu_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13937">
        <property type="entry name" value="DUF4212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03647">
        <property type="entry name" value="Na_symport_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4212" evidence="2">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="10059" checksum="26040F5221DC4830" modified="2008-04-29" version="1">MSFESNDKAEGYWRENLRLVLGLLAIWAAVSFGCGILLVDVLNEFHFMGFKLGFWFAQQGAMYVFVALIFVYVAKANALDKKYNVHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT2</accession>
    <name>B1KJT2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325455.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2844"/>
    <dbReference type="EnsemblBacteria" id="ACA87119">
        <property type="protein sequence ID" value="ACA87119"/>
        <property type="gene ID" value="Swoo_2844"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2844"/>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_1_6"/>
    <dbReference type="OMA" id="HHHEFID"/>
    <dbReference type="OrthoDB" id="1094814at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021812">
        <property type="entry name" value="DUF3391"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11871">
        <property type="entry name" value="DUF3391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="137"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="45046" checksum="FF2E192C571219C2" modified="2008-04-29" version="1">MARAEQVHLPLAKLQIGLTIKLPLSWKNHPFLFNRVQIKEEVQIELIKSLGVPYVILLSGHELLPEEEESSNDSEEVEVEQQTSEVDINMEVRKSLRLSQQRFIKSVNDTRTAFSKTGSDPEGAYRSSAAIVEEMLEHMSEVELPELALVSAGESDSSITQHGISVAVVALMIAKTMNLNMSDMRDIALGCLYHDIGKLKVPDTIRRKRGALTDHEANFMKMHPNFGYDMMSKSGLFPEAVLNIILHHHEFIDGSGYPDGLKGKKIPLPTQIVSLANDFDRQLWAESVRSPQVALGYLFKKRAGKHDEALISSLVKILGIYPPGTIVQLSDMSVGKVMMTTKEVKQPQVWACEADGSESNLRFLIQEKVTVEKVLKVEELSEGAMKSLQPEMGISFYFNSAPES</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT5</accession>
    <name>DNLJ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase</fullName>
            <ecNumber evidence="1">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ligA</name>
        <name type="ordered locus">Swoo_2847</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide.</text>
            <dbReference type="EC" id="6.5.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325458.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJT5"/>
    <dbReference type="SMR" id="B1KJT5"/>
    <dbReference type="STRING" id="392500.Swoo_2847"/>
    <dbReference type="EnsemblBacteria" id="ACA87122">
        <property type="protein sequence ID" value="ACA87122"/>
        <property type="gene ID" value="Swoo_2847"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2847"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007764_2_1_6"/>
    <dbReference type="OMA" id="HDVEHEI"/>
    <dbReference type="OrthoDB" id="241401at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000380471" description="DNA ligase">
        <location>
            <begin position="1"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="590"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="31"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="80"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <sequence length="670" mass="73316" checksum="9CDEF0734DC8FB05" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJY8</accession>
    <name>B1KJY8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2902</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325511.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2902"/>
    <dbReference type="EnsemblBacteria" id="ACA87175">
        <property type="protein sequence ID" value="ACA87175"/>
        <property type="gene ID" value="Swoo_2902"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2902"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047522_3_4_6"/>
    <dbReference type="OMA" id="VSHFRQS"/>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="239"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="341" mass="39096" checksum="295FEF9458084787" modified="2008-04-29" version="1">MKYVQSYKRNMLVGDQSYPAYQLRNLLNYLKVHYGDEVVDKLCSQIGLGISELEHLQLIYVWQADFAMEFLQQYTQDPEIGAKVGSQYLVKDLDFLLTFFNQCKTIGECLQFVLSHPERVGSFTDTLVTNEDGELRIRWLNTGRINRERYSCQFQHSVCGLVKIGCGLAGQTIRFGRISLAEEERDASFLASVTGADVQFASEFNEWSIEHKYLSLPVTYDFDKNLINTVSNQQPSYIEHLLDQLRSSFPDCPNMEQMAEIQNISSRTLRRKISLAGSSYQKLVDQVRSQAAIGLILSEEHKVEDIAEVMGFGDVSHFRQSFKHWLGHPPGHFLRLNEKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK27</accession>
    <name>B1KK27_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylation site containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326984.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4406"/>
    <dbReference type="EnsemblBacteria" id="ACA88658">
        <property type="protein sequence ID" value="ACA88658"/>
        <property type="gene ID" value="Swoo_4406"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4406"/>
    <dbReference type="eggNOG" id="COG4967">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110706_0_0_6"/>
    <dbReference type="OMA" id="GPSEWKW"/>
    <dbReference type="OrthoDB" id="2063277at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="184" mass="19778" checksum="D545D03B3B78C01A" modified="2008-04-29" version="1" precursor="true">MAANSLNSSNSIKGFTLIELVVGMVVLSIALVMLSSMLFPQADRAADTLHRVRSAELAHSILNEIWGKRYDQNTNANGGVPACGAAARADLGLPAGLDCTDAANLGPDTGEVRNTFNDVDDYHGLSETSNMLNSSDTYLSQYINYQLSVAVTYPNADRNSKLVTIDVTTPRGEVITYNAIRSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK42</accession>
    <name>B1KK42_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Conserved hypothetical biogenesis protein MshI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4421"/>
    <dbReference type="EnsemblBacteria" id="ACA88673">
        <property type="protein sequence ID" value="ACA88673"/>
        <property type="gene ID" value="Swoo_4421"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4421"/>
    <dbReference type="eggNOG" id="COG4972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075009_0_0_6"/>
    <dbReference type="OMA" id="FARLAFW"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="34090" checksum="80773822CE2E2EAA" modified="2008-04-29" version="1">MFSRLAFWRKSSVKRRLGVYVCPEKVVVYHLNDENQQSDVASNNSKEFAFDGVNWNRLFAELGKEFGPAQLQITLSSPYYQLLLVDKPNVDSEEMTQALLWSVKDMISQPVTDIHLDYFESPQQNSAKLSVVIVDRQKLTALILAAKEQEMQLAGITIEEMAISNLFWQEPQAKLVISHQPGQEILLTVIRQGDLYMQRRVRGFNQIDTASAEELGFGMADNLSLELQRSMDYFESQLRQAPVSSIELLINGQTERLAELVSVNFNQEVNAIAAEGVESIMAKLALTEIERDEVELVEAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKD5</accession>
    <name>B1KKD5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324121.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1487"/>
    <dbReference type="EnsemblBacteria" id="ACA85775">
        <property type="protein sequence ID" value="ACA85775"/>
        <property type="gene ID" value="Swoo_1487"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1487"/>
    <dbReference type="HOGENOM" id="CLU_2107992_0_0_6"/>
    <dbReference type="OMA" id="MNCTREN"/>
    <dbReference type="OrthoDB" id="1930741at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764995" evidence="1">
        <location>
            <begin position="26"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="122" mass="13396" checksum="4AA6B293BAB78AD8" modified="2008-04-29" version="1" precursor="true">MMNKTRLVLIFASLFISLVSFNSYAGGWATPAVPTHIEIERGGGFLVVGAFGNAGTCTKGDKFYVKIDHPQYDKIYATVLAAYMAGKKVRPYIHTCAPVTWHSTTAVTYNIMTRSGALYIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV4</accession>
    <name>B1KKV4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Uridine phosphorylase</fullName>
            <ecNumber evidence="5 10">2.4.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4509</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>phosphate + uridine = alpha-D-ribose 1-phosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:24388"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.3" evidence="5 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327086.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4509"/>
    <dbReference type="EnsemblBacteria" id="ACA88760">
        <property type="protein sequence ID" value="ACA88760"/>
        <property type="gene ID" value="Swoo_4509"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4509"/>
    <dbReference type="eggNOG" id="COG2820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068457_0_0_6"/>
    <dbReference type="OMA" id="MSDVFHL"/>
    <dbReference type="OrthoDB" id="1028277at2"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00633"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004850">
        <property type="term" value="F:uridine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018016">
        <property type="entry name" value="Nucleoside_phosphorylase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010058">
        <property type="entry name" value="Uridine_phosphorylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01718">
        <property type="entry name" value="Uridine-psphlse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01232">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="11">
        <location>
            <begin position="19"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="26882" checksum="F7F76BF934F623DF" modified="2008-04-29" version="1">MSDVFHLGLTKKMLDGASLAIVPGDPERVKRIAELMEGASFLASHREYTSYLAYIDGKAVVICSTGIGGPSTSIAVEELAQLGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEFPAVANFECTTAMVAASRDAGLEPHIGITASSDTFYPGQERYDTVSGRVTRQFKGSMQEWQDLGVLNYEMESSTLFTMCASQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAVSIVVAAAKKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW7</accession>
    <name>B1KKW7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327099.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4522"/>
    <dbReference type="EnsemblBacteria" id="ACA88773">
        <property type="protein sequence ID" value="ACA88773"/>
        <property type="gene ID" value="Swoo_4522"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4522"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_0_6"/>
    <dbReference type="OMA" id="GNKKGWL"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="28"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="526" mass="57618" checksum="D92A8EB108D3AD50" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL44</accession>
    <name>MOBA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Molybdenum cofactor guanylyltransferase</fullName>
            <shortName evidence="1">MoCo guanylyltransferase</shortName>
            <ecNumber evidence="1">2.7.7.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GTP:molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Mo-MPT guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Molybdopterin-guanine dinucleotide synthase</fullName>
            <shortName evidence="1">MGD synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mobA</name>
        <name type="ordered locus">Swoo_0084</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide</text>
            <dbReference type="Rhea" id="RHEA:34243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:71310"/>
            <dbReference type="EC" id="2.7.7.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MobA family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.77" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322734.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL44"/>
    <dbReference type="SMR" id="B1KL44"/>
    <dbReference type="STRING" id="392500.Swoo_0084"/>
    <dbReference type="PRIDE" id="B1KL44"/>
    <dbReference type="EnsemblBacteria" id="ACA84385">
        <property type="protein sequence ID" value="ACA84385"/>
        <property type="gene ID" value="Swoo_0084"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0084"/>
    <dbReference type="eggNOG" id="COG0746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055597_5_1_6"/>
    <dbReference type="OMA" id="IDFWYAK"/>
    <dbReference type="OrthoDB" id="2019898at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061603">
        <property type="term" value="F:molybdenum cofactor guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02503">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00316">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013482">
        <property type="entry name" value="Molybde_CF_guanTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02665">
        <property type="entry name" value="molyb_mobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000115809" description="Molybdenum cofactor guanylyltransferase">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00316"/>
        </source>
    </evidence>
    <sequence length="196" mass="21701" checksum="3925589202992F98" modified="2008-04-29" version="1">MSLRIDAVILAGGMARRMGGNDKGLVELLDKPMIEHSIDRIKPQVKEIMINANRNQSRYADLGYPVFSDEDSGYLGPLAGMITAMGQTQADYLLVVPCDCPLLPLDLVERMLTKIQSEGAELAVASDGKREQPVVLLLKPSLRDSMKAFLDGGERKIDFWYAKHHCVVTEFSDQPNAFINVNTPEQKQQLAEAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL55</accession>
    <name>B1KL55_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0095</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322745.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0095"/>
    <dbReference type="EnsemblBacteria" id="ACA84396">
        <property type="protein sequence ID" value="ACA84396"/>
        <property type="gene ID" value="Swoo_0095"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0095"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_86_7_6"/>
    <dbReference type="OMA" id="CHCVSGP"/>
    <dbReference type="OrthoDB" id="870493at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="231"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="265"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="451" mass="49729" checksum="379DFD2F439EAD16" modified="2008-04-29" version="1">MSLLELDGVSFRYDCGEPFILEDLNLQIKPGECHCISGPTGSGKSTLLKLIMGVLSRPFDGEMIRTGDLTLGLVMQDPNVQFIRQSVGAEVAFALENLCVPLELMRAKVISALRKVGLFVRLDMPIEQLSLGQKYRVMIAAQLVFEPEILLLDEPWAQLDNSGVEELILVLSQLKRDGVAVLLVDHNPRAFSELVDAFYHMKDGSLVAGCLPPVTVEHLVGAPVLLDTCVVQAEPFEFSFIDQAPLFKSVEPLAIYSGEIIALIGDNGTGKSSFLKTLAGIQADIGKLPLTVLGKQPKLGIFGAEMGLLLQAPNRQLFEETVLGELQFSLKRFGLPLHRAEQLLDELELSHLAEHSPHKLSYGQQHMVALASLVCLRPKVLLLDDPFAGLDAEYLNRVWSLLVNLSHRGSAILLTSHRQMVNLPVTRYWQVEAGFLRCEYDPSVTQTLQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLD0</accession>
    <name>B1KLD0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324201.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1569"/>
    <dbReference type="EnsemblBacteria" id="ACA85855">
        <property type="protein sequence ID" value="ACA85855"/>
        <property type="gene ID" value="Swoo_1569"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1569"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="NAPSFYY"/>
    <dbReference type="OrthoDB" id="38744at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="856"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="881"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="910"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="978"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1026" mass="110845" checksum="C117738D1B871191" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLH6</accession>
    <name>B1KLH6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324247.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1615"/>
    <dbReference type="EnsemblBacteria" id="ACA85901">
        <property type="protein sequence ID" value="ACA85901"/>
        <property type="gene ID" value="Swoo_1615"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1615"/>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_39_6"/>
    <dbReference type="OMA" id="SEHARME"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="28"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="143"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="370" mass="40352" checksum="329E930751C3A2D2" modified="2008-04-29" version="1">MSVSPQIQQDTISQHSPKWLDIAPAANMSNRMEHILQAMPSGIVIINGDGVVTDTNPVAVKLLGLPLEGLKWIQVINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPESGQLIVLTDLTETRILQKNLSHLQRLSALGKMVATLAHQVRTPLTAALLYASNLGSPKLTDVSRKRFQGKLVDRLNELEHQVNDMLLMAKGRQQEQGEAEHISTVMESVLANCEPIAEQNRCELEFIDSSKSPFLANSSALSSAINNLVVNSIEAGSTKVKIQGYETQSNLHIDIIDNGKGLDKAMQQKVLEPFFTTKAQGTGLGLAVVQSVVANHSGKLQLRCEKTKGCTASLVFPKLLGQDSETFDKPLVKEVDEGAKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW0</accession>
    <name>B1KLW0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327165.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4590"/>
    <dbReference type="EnsemblBacteria" id="ACA88840">
        <property type="protein sequence ID" value="ACA88840"/>
        <property type="gene ID" value="Swoo_4590"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4590"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_8_6"/>
    <dbReference type="OMA" id="LWFYTLA"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="178"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="367" mass="41194" checksum="7C815390F38E1C4B" modified="2008-04-29" version="1">MNNTDTASTKTTQTSEDKLSWVYLINLVFYLIPIIVGNMQIWEIGVSLLTLIPFVYCYFWAYRSPRDKAHIPILAMIALGILITPINTGSLSLFTFAGFFIGFYYPLKTATFCFFALVAALGALNLYIGIEHYYFVTYGSLLIAGVGLFGIAERKRVEAKCREQQSQSEISQLAAMLERERIARDLHDIMGHNLSSISLKAELAQKLLDKNQQIQAQEQLKELNQIARESLSQIRQTVSGYKHKGLTSSVMLLCQTLRDKGLSVSLEGDVPQLNSKVETQIILSLTELCNNIIRHSQADLCSICFSESATDITLEVIDNGKLKQLTEGNGLNGIRERLAEFQGRLDYDLTQECRFSIILPKQGNLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW2</accession>
    <name>B1KLW2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="3 6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recG</name>
        <name evidence="9" type="ordered locus">Swoo_4592</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327167.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4592"/>
    <dbReference type="EnsemblBacteria" id="ACA88842">
        <property type="protein sequence ID" value="ACA88842"/>
        <property type="gene ID" value="Swoo_4592"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4592"/>
    <dbReference type="eggNOG" id="COG1200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005122_7_1_6"/>
    <dbReference type="OMA" id="DNGFQAC"/>
    <dbReference type="OrthoDB" id="234717at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004609">
        <property type="entry name" value="ATP-dep_DNA_helicase_RecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00643">
        <property type="entry name" value="recG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="281"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="480"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="691" mass="76367" checksum="CB0296CF77577689" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM13</accession>
    <name>B1KM13_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutamine synthetase</fullName>
            <ecNumber evidence="2 7">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4643</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Oligomer of 12 subunits arranged in the form of two hexagons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="2 7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327217.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4643"/>
    <dbReference type="EnsemblBacteria" id="ACA88893">
        <property type="protein sequence ID" value="ACA88893"/>
        <property type="gene ID" value="Swoo_4643"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4643"/>
    <dbReference type="eggNOG" id="COG0174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_1_2_6"/>
    <dbReference type="OMA" id="PHPHEFE"/>
    <dbReference type="OrthoDB" id="416474at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001637">
        <property type="entry name" value="Gln_synth_I_adenylation_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00182">
        <property type="entry name" value="GLNA_ADENYLATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="8">
        <location>
            <begin position="102"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="4">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="469" mass="51621" checksum="B0469A0A065CEAC5" modified="2008-04-29" version="1">MSAELVLQQIEELEVKFVDLRFTDTIGKEQHVSIPSHQVDADFFEDGKMFDGSSISGWKGINESDMVLMPDPESFVLDPFTAETTANIRCDILNPGTMTGYNRDPRSIAKKAEDYLRSTGIADTVLIGPEPEFFLFDDVKFSSDMSGCFYKVDAEEAAWNSGTSYEDGNKGHRPGVKGGYFPVAPVDSSQDIRSAMCLVLEEMGQVVEAHHHEVATAGQNEIATRFNTLTLKADEVQVLKYVIHNVAHAYNKTATFMPKPIVGDNGSGMHVHQSLAKDGVNIFAGDKYGGLSETALFYIGGIIKHARAINAFANPSTNSYKRLIPHFEAPVMLAYSAANRSASIRIPVVPSAKARRIELRFGDPMANPYLAFSAMLMAGLDGIQNKIHPGEAMDKDLYDLPAEEAAEIPTVATSLENALECLDADREFLTRGDVFSNDFIDSYIALKSADVERINQTTHPVEFELYYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM31</accession>
    <name>B1KM31_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Heme exporter protein C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytochrome c-type biogenesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ccmC</name>
        <name evidence="10" type="ordered locus">Swoo_4661</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CcmC/CycZ/HelC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327235.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4661"/>
    <dbReference type="EnsemblBacteria" id="ACA88911">
        <property type="protein sequence ID" value="ACA88911"/>
        <property type="gene ID" value="Swoo_4661"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4661"/>
    <dbReference type="eggNOG" id="COG0755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066538_2_0_6"/>
    <dbReference type="OMA" id="FHVPMWF"/>
    <dbReference type="OrthoDB" id="955123at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003557">
        <property type="entry name" value="Cyt_c_biogenesis_CcmC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01386">
        <property type="entry name" value="CCMCBIOGNSIS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01191">
        <property type="entry name" value="ccmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="9">
        <location>
            <begin position="30"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="27490" checksum="4601406A7D792127" modified="2008-04-29" version="1">MWKWLHSYADPERAYNLSGKLLPWFSMLAISLIGIGSVWGLAFAPVDYQQGDSYRIIFIHVPAASMSMSAYMAMATSAFIGLVWQIKSADWAAAAIAPIGAVVTFIALITGATWGKPMWGTWWVWDARLTSELVLLFLYLGVIALYASFEDKVLAARAAGILAIVGVINIPIIKYSVEWWNSLHQPATIKITEKSSMAAEMLYPLLINILGFGLMIGAITLVRFRAEILARNSMRPWVRELAMTEGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMA7</accession>
    <name>B1KMA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaI subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322869.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0219"/>
    <dbReference type="EnsemblBacteria" id="ACA84520">
        <property type="protein sequence ID" value="ACA84520"/>
        <property type="gene ID" value="Swoo_0219"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0219"/>
    <dbReference type="eggNOG" id="COG3396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070585_0_0_6"/>
    <dbReference type="OMA" id="NGDFAHT"/>
    <dbReference type="OrthoDB" id="1389523at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011882">
        <property type="entry name" value="PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037834">
        <property type="entry name" value="PA_CoA_Oase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02158">
        <property type="entry name" value="PA_CoA_Oxy3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="28327" checksum="8C821F7283D255CB" modified="2008-04-29" version="1">MNANLLKYVTGLADDSMVLSQRLSQWCSHGPTLEEDIALTNVALDYLGRARMFYQYAAELEGLGRSEDDFAMWRSEREYSNLLINELPNGDFAFTLVRQWLLDEFYQLYLSSLLLSTDKTLTSIAAKAIKETGYHLIRSRQWLDVLANGTDESRQRINDALDEIIGYIPELFTNTDAEKALPDIAVSRAELEPLWQQQIAQFCEQIGLVFPEVQWQVTGGREGVHSEHLGYLLTEMQCLARSHPTAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG6</accession>
    <name>B1KMG6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324310.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1679"/>
    <dbReference type="EnsemblBacteria" id="ACA85964">
        <property type="protein sequence ID" value="ACA85964"/>
        <property type="gene ID" value="Swoo_1679"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1679"/>
    <dbReference type="eggNOG" id="COG1331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_366765_0_0_6"/>
    <dbReference type="OrthoDB" id="854580at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028250">
        <property type="entry name" value="DsbDN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036929">
        <property type="entry name" value="DsbDN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="DUF255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="PTHR42899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11412">
        <property type="entry name" value="DsbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredox_DsbH" evidence="1">
        <location>
            <begin position="64"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC" evidence="2">
        <location>
            <begin position="645"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="760" mass="86658" checksum="43D39098DCE6B3A7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH8</accession>
    <name>B1KMH8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CDP-glycerol:poly(Glycerophosphate) glycerophosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1691</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-glycerol glycerophosphotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324322.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1691"/>
    <dbReference type="EnsemblBacteria" id="ACA85976">
        <property type="protein sequence ID" value="ACA85976"/>
        <property type="gene ID" value="Swoo_1691"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1691"/>
    <dbReference type="eggNOG" id="COG1887">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029598_2_0_6"/>
    <dbReference type="OMA" id="NPRTDYY"/>
    <dbReference type="OrthoDB" id="1162846at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047355">
        <property type="term" value="F:CDP-glycerol glycerophosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019350">
        <property type="term" value="P:teichoic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007554">
        <property type="entry name" value="Glycerophosphate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043149">
        <property type="entry name" value="TagF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04464">
        <property type="entry name" value="Glyphos_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0777">Teichoic acid biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="432" mass="50528" checksum="9A92907C8E219AC7" modified="2008-04-29" version="1">MTFFTAIIRKIIYHTAGLCPRVNKAVLGSYKNQFSDNAKYLYLHWQHTGLIRSIWISGDNAVIKRLRKEGFEAYNRRSILGIFHCLTAKFYFYNSYVGDINQYFAKGAVKVNLWHGSPLKKIEFDITSGPLAHTYQSDTLIGDWKNRLHFHQQHIKPDMMLSPSPVIDSLFSSAFRLAPHQLIRSGNPRTDYFKRYPEQTKSIPELLNTQYKKVILYVPTWRDSGINNKSDGQNGAIENPYDKGFNWAALSKQLKRNKQLFLVRFHPNEAHLGKDLNQYSNIIDISHWEDVYNILQGVDLLITDQSSLFIDLLLHQVPILFYSFEQGGKPEKLREIYDYAEYLPLVGQVTSNEAINNRYRVYQFQALMERLDRDETFHISPSTINEYQLLRNIFWQQQKCDAFENIERCLFSNEKQNKIKGTEKSGLRPARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMP9</accession>
    <name>B1KMP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-beta hydroxysteroid dehydrogenase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325763.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3156"/>
    <dbReference type="EnsemblBacteria" id="ACA87427">
        <property type="protein sequence ID" value="ACA87427"/>
        <property type="gene ID" value="Swoo_3156"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3156"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_1_6"/>
    <dbReference type="OMA" id="WGPGDTQ"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003854">
        <property type="term" value="F:3-beta-hydroxy-delta5-steroid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3Beta_HSD" evidence="1">
        <location>
            <begin position="35"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="361" mass="39197" checksum="E6CE452CBBB01C2F" modified="2008-04-29" version="1">MSEMPDMNGLELHNFAIEEQVALSKLKAKAHHAFVTGAGGFLGKAICKRLLAAGIQVTGFARGDYPELSAMGVKMIKGDIADQTSVIEAMKGCDLVFHVASKAGVWGSKLSYFSPNVAGAAHIIQGCKQLGIANLVYTSTPSVTFAGEDEAGLDETAPYAETFLNYYGESKAVAEKMMIDANSEVLKTVSLRPHLIWGPEDPHLVPRVISRAKAGRLKLVGREDKLVDTIYVDNAAYAHILAAINLSEPDTKVAGKAYYLSNDEPITMADMLNKILACVDMPKVTQRVPASLAYGVGVILEAYYSLMNKQEEPVMTRFVARQLSTSHYFDISAAKTDFGYSAIVSIDQGMVKLREYLTEIE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMX5</accession>
    <name>RL29_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmC</name>
        <name type="ordered locus">Swoo_4682</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012144642.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMX5"/>
    <dbReference type="SMR" id="B1KMX5"/>
    <dbReference type="STRING" id="392500.Swoo_4682"/>
    <dbReference type="EnsemblBacteria" id="ACA88932">
        <property type="protein sequence ID" value="ACA88932"/>
        <property type="gene ID" value="Swoo_4682"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4682"/>
    <dbReference type="eggNOG" id="COG0255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158491_1_2_6"/>
    <dbReference type="OMA" id="RFQMATS"/>
    <dbReference type="OrthoDB" id="2063644at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000121817" description="50S ribosomal protein L29">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <sequence length="63" mass="7115" checksum="5E54E68E30D8E3E0" modified="2008-04-29" version="1">MKASELTEKSVEELNAELLGLLREQFNLRMQHATGQLTQTHQLKIVRRNIARVKTIITSKAGA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ3</accession>
    <name>RL1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplA</name>
        <name type="ordered locus">Swoo_4700</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327269.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMZ3"/>
    <dbReference type="SMR" id="B1KMZ3"/>
    <dbReference type="STRING" id="392500.Swoo_4700"/>
    <dbReference type="EnsemblBacteria" id="ACA88950">
        <property type="protein sequence ID" value="ACA88950"/>
        <property type="gene ID" value="Swoo_4700"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4700"/>
    <dbReference type="eggNOG" id="COG0081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062853_0_0_6"/>
    <dbReference type="OMA" id="GWTDVDV"/>
    <dbReference type="OrthoDB" id="1671455at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0810">Translation regulation</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000141461" description="50S ribosomal protein L1">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <sequence length="233" mass="24451" checksum="760D1A02DA5B1F2C" modified="2008-04-29" version="1">MAKLTKRARLIREKVEVTKNYDINEAVALLKELATAKFVESVDVAVNLGVDPRKSDQNVRGATVLPHGTGREVRVAVFTQGANAEAATAAGAELVGMDELAAQVKAGEMNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKTGTVTPNVAEAVKNAKAGQVRYRTDKNGIIHTTIGKVDFETVQLKENLEALIGALVKAKPASAKGVFLKKVSISTTMGAGVAVDQATLAKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ9</accession>
    <name>B1KMZ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional ligase/repressor BirA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Biotin operon repressor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin--[acetyl-CoA-carboxylase] ligase</fullName>
            <ecNumber evidence="3">6.3.4.15</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin--protein ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin-[acetyl-CoA carboxylase] synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">birA</name>
        <name evidence="5" type="ordered locus">Swoo_4706</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + biotin + L-lysyl-[protein] = AMP + diphosphate + H(+) + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:11756"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.15" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327274.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4706"/>
    <dbReference type="EnsemblBacteria" id="ACA88956">
        <property type="protein sequence ID" value="ACA88956"/>
        <property type="gene ID" value="Swoo_4706"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4706"/>
    <dbReference type="eggNOG" id="COG0340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051096_4_0_6"/>
    <dbReference type="OMA" id="AVWKHIE"/>
    <dbReference type="OrthoDB" id="1842956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00978">
        <property type="entry name" value="Bifunct_BirA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030855">
        <property type="entry name" value="Bifunct_BirA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0092">Biotin</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="4">
        <location>
            <begin position="66"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="3">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Biotin binding" evidence="3">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Biotin binding" evidence="3">
        <location>
            <begin position="116"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="320" mass="35379" checksum="374B14D8C5A79BD3" modified="2008-04-29" version="1">MIDQWQRKREILSVLDSEQFVSGEALAAKLGVSRTAIANHISALEEYGVEVFSVKGKGYKLANSLSLIDETLLKEAVTQRCFYYDEIPSTNAFLLKHCEELSSGDICVAEYQSAGRGRRGRTWVSPYGCHLYCSMYWNLSQGMAQATGLSLVVACSLVKVLNNFGIHGLGVKWPNDIYLDNKKLAGVLVEMNGQADTECHLVIGIGINMSMSRAQGDKIDQPWSDLSQSRVVPSKTELTISLQRQLNEDLTLFEKEGLSAFLIRWKEADIFDGKHVKLLMGEQRIDGVCKGIDKTGSILLKTDKGVESFVGGEISLRSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN44</accession>
    <name>B1KN44_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327318.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89001">
        <property type="protein sequence ID" value="ACA89001"/>
        <property type="gene ID" value="Swoo_4752"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4752"/>
    <dbReference type="eggNOG" id="ENOG5030IYA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031876_0_0_6"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767225" evidence="1">
        <location>
            <begin position="24"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="45516" checksum="48944AE9AE8136C4" modified="2008-04-29" version="1" precursor="true">MNLNTRSLLSLLLFVSLAMPLQAAVKPYSKVGSSPIQASIKPYTAGLIMRGKYDGTKCETPRGNMAAGYCQVYWKDIEPVKGQFNWSVIDRAVTAAKSYNAAQGLTDKDGYKVMIRIRTGVYAPDWVKSDPNVGKISWQFKNSSPKQTFQLPLFWNTPYQNHYENLMQAAANRYDNELSIGGVAASMCMTVHTEIMWNRTGRKEVRAANMSTMRALGDKSYTNEKDYACLQRQIQIHSNTWQKTPTLFGSHLYQVYNYSNGGKSSDYNKTKQLFNECRSSSKLGKRCVLGNNSLRHDEVNNDGSVNQLLFEIAQAGDPVYFQTNVFKSDRKKRFGVDELKGAMDNAANWGAVAVEIPMAWDCSDYFNKSGCSSATVKQRQGEFHSYQNRLKDNVVRISPVKETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN69</accession>
    <name>B1KN69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322915.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0265"/>
    <dbReference type="EnsemblBacteria" id="ACA84566">
        <property type="protein sequence ID" value="ACA84566"/>
        <property type="gene ID" value="Swoo_0265"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0265"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_2_6"/>
    <dbReference type="OMA" id="HIAFSFN"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="312" mass="35243" checksum="3EEFDDF80AA1F40C" modified="2008-04-29" version="1">MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRLNLDDELFYRHGNKLVATQLARRLGPAVHQIINDMNQIMTQEVFNPAVYEGRFSLAMRESTFELLAAKLSAHVLNLAPNIRLDIHFKNTVGFDGLVKGTLDFIILPHDLSQPPIARSELVWETLINDEMVCLMNASHPLAIKSQLSIDDYLNYSHVGISDTDLNIPFFEMQLAQQQRSRAVPISVADFGSAVLMCHHSELLFTCSRRWAENAFQANGLVTKRLPFDYGEVAYSLVWHRQSMNDPALRWLYEQIVGFTTKLGAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNA6</accession>
    <name>B1KNA6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="2">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">coaE</name>
        <name evidence="3" type="ordered locus">Swoo_0302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CoaE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322952.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0302"/>
    <dbReference type="EnsemblBacteria" id="ACA84603">
        <property type="protein sequence ID" value="ACA84603"/>
        <property type="gene ID" value="Swoo_0302"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0302"/>
    <dbReference type="eggNOG" id="COG0237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057180_1_2_6"/>
    <dbReference type="OMA" id="QMDIEQK"/>
    <dbReference type="OrthoDB" id="1515383at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="22270" checksum="A369819EE591A908" modified="2008-04-29" version="1">MTNLVVGLTGGIGSGKTTVANIFAELGIELVDADIVAREVVAIGSLGLTKIAQHFGADILNSDSTLNRAKLREHIFSKPEELEWLNALLHPIIRTEMLKQLDNTRSPYSILIAPLLFENGLDRLVDRTLLVDISPEQQRNRTKIRDSVTAEQVQKIIDSQASREDKLSKADDVIDNHGERSALRNKVVALHNNYLKLSNNT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KND3</accession>
    <name>ARGC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="1">AGPR</shortName>
            <ecNumber evidence="1">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="1">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argC</name>
        <name type="ordered locus">Swoo_0329</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322979.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KND3"/>
    <dbReference type="SMR" id="B1KND3"/>
    <dbReference type="STRING" id="392500.Swoo_0329"/>
    <dbReference type="EnsemblBacteria" id="ACA84630">
        <property type="protein sequence ID" value="ACA84630"/>
        <property type="gene ID" value="Swoo_0329"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0329"/>
    <dbReference type="eggNOG" id="COG0002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006384_0_1_6"/>
    <dbReference type="OMA" id="PHLTPMI"/>
    <dbReference type="OrthoDB" id="951261at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0055">Arginine biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000096738" description="N-acetyl-gamma-glutamyl-phosphate reductase">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <sequence length="326" mass="35311" checksum="85D095DF65E4FD91" modified="2008-04-29" version="1">MKSIAIIGASGYTGAQITSLIDADKNLVIQGLYVSENSVDKGKPLSELYPTYSHISLPLSPLSDEAKALIAEQADGVVLATDHAVSLHLAAWFFEQGLTVFDLSGAYRFSDKSQYPQWYGFEHDYPQVLSHAVYGLAEWNGADIADSKMIAVPGCYPTASLTALKPIHSLMTSSLPVINAVSGVTGAGRKAQLNTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILATITVQLKEGVTQADIEQAYAIYDNAPLVTVKQNQFPKVDDVTNTPNCHLGWKFDPKTGYLVVASAIDNLMKGAASQAHQCIKIHFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KND5</accession>
    <name>B1KND5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ornithine carbamoyltransferase</fullName>
            <ecNumber evidence="3">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0331</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322981.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0331"/>
    <dbReference type="EnsemblBacteria" id="ACA84632">
        <property type="protein sequence ID" value="ACA84632"/>
        <property type="gene ID" value="Swoo_0331"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0331"/>
    <dbReference type="eggNOG" id="COG0078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043846_3_2_6"/>
    <dbReference type="OMA" id="VYVKNWS"/>
    <dbReference type="OrthoDB" id="988597at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="147"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="127"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="5">
        <location>
            <begin position="225"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="260"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="302" mass="32942" checksum="A3B7C8CBE0BC06C7" modified="2008-04-29" version="1">MDHLLSIKDLSQEQLKELLSLAKKIKANPAEYRHALDGKSVVMLFEKPSLRTRVSFDIGINKLGGHCLYLDQQNGALGKREPVSDFAANISCWADAIVARTFLHSTIETLAEHGSVPVINALSDLYHPCQGLADFLTLSEQFDDVSQVKLAYVGDGNNVTHSLMYGAAILGATMTVVCPPGHFPDGQVVVEAQALAAKYGGKLILTSDVEQLAEQDAIYTDTWISMGDDTDLSEIKAKFQPYQVNEAMMKQAGASYFMHCLPAYREVEVTAEVVDGEGSLILQQAENRMHAQNAVLVTLLGQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNI7</accession>
    <name>HSCA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chaperone protein HscA homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hscA</name>
        <name type="ordered locus">Swoo_1780</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324410.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNI7"/>
    <dbReference type="SMR" id="B1KNI7"/>
    <dbReference type="STRING" id="392500.Swoo_1780"/>
    <dbReference type="PRIDE" id="B1KNI7"/>
    <dbReference type="EnsemblBacteria" id="ACA86064">
        <property type="protein sequence ID" value="ACA86064"/>
        <property type="gene ID" value="Swoo_1780"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1780"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_2_1_6"/>
    <dbReference type="OMA" id="PDPHQRR"/>
    <dbReference type="OrthoDB" id="161217at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10236">
        <property type="entry name" value="HscA_like_NBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00679">
        <property type="entry name" value="HscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042039">
        <property type="entry name" value="HscA_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010236">
        <property type="entry name" value="ISC_FeS_clus_asmbl_HscA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01991">
        <property type="entry name" value="HscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000131695" description="Chaperone protein HscA homolog">
        <location>
            <begin position="1"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00679"/>
        </source>
    </evidence>
    <sequence length="620" mass="66245" checksum="50C59E6C7D13B910" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNZ5</accession>
    <name>B1KNZ5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sodium/glutamate symporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gltS</name>
        <name evidence="2" type="ordered locus">Swoo_4777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the sodium-dependent transport of glutamate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327343.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4777"/>
    <dbReference type="EnsemblBacteria" id="ACA89026">
        <property type="protein sequence ID" value="ACA89026"/>
        <property type="gene ID" value="Swoo_4777"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4777"/>
    <dbReference type="eggNOG" id="COG0786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040907_0_0_6"/>
    <dbReference type="OMA" id="PTAMVNM"/>
    <dbReference type="OrthoDB" id="1284248at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015501">
        <property type="term" value="F:glutamate:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015813">
        <property type="term" value="P:L-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02062">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004445">
        <property type="entry name" value="GltS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36178">
        <property type="entry name" value="PTHR36178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03616">
        <property type="entry name" value="Glt_symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00210">
        <property type="entry name" value="gltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0915">Sodium</keyword>
    <keyword evidence="1" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="1" id="KW-0769">Symport</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="407" mass="43868" checksum="FF3E4978D303DE67" modified="2008-04-29" version="1">MSTVYSIGELESFLVAILVLFIGHTINRHVPLFKKYNIPEPIVGGLIVAAVITILHFNQISIRFTLSMQNTLMLMFFSTVGLAASYKLLLKGGTKVFMFLGVTSLFILVQNAVGVSMATALGLEPFMGLIAGSITLSGGHGTGAAWAQTFYEDYGVNTLEFAMAAATFGLVMGGIIGGPVAQRLINKNNLVSSYGVGGNHHKDHPELVTYDQLEEDRVTAKSILEVLFILLLCVAGAKWIGTLISYLDISWLKMPEFVYALFLGVVIANITELSHGYKIKSESVDVLGTVSLSLFLSMALMNLKLWEIFDLALPLLAILLVQTLTLALFAYFITFRFMGSNYDAAVMVGGHCGFGMGATPTAVMNMGALVSRTGPSPQAFMVVPIVGAFFIDIVNAIILKGYLSFIG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP55</accession>
    <name>HUTH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidine ammonia-lyase</fullName>
            <shortName evidence="1">Histidase</shortName>
            <ecNumber evidence="1">4.3.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hutH</name>
        <name type="ordered locus">Swoo_4837</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidine = NH4(+) + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:21232"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="EC" id="4.3.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAL/histidase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327403.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KP55"/>
    <dbReference type="SMR" id="B1KP55"/>
    <dbReference type="STRING" id="392500.Swoo_4837"/>
    <dbReference type="EnsemblBacteria" id="ACA89086">
        <property type="protein sequence ID" value="ACA89086"/>
        <property type="gene ID" value="Swoo_4837"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4837"/>
    <dbReference type="eggNOG" id="COG2986">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014801_4_0_6"/>
    <dbReference type="OMA" id="CAPQVAG"/>
    <dbReference type="OrthoDB" id="715502at2"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004397">
        <property type="term" value="F:histidine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00229">
        <property type="entry name" value="His_ammonia_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005921">
        <property type="entry name" value="HutH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01225">
        <property type="entry name" value="hutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0369">Histidine metabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000100454" description="Histidine ammonia-lyase">
        <location>
            <begin position="1"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="modified residue" description="2,3-didehydroalanine (Ser)" evidence="1">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="cross-link" description="5-imidazolinone (Ala-Gly)" evidence="1">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00229"/>
        </source>
    </evidence>
    <sequence length="510" mass="54116" checksum="13DB16374DBA5181" modified="2008-04-29" version="1">MSHLVLKPGTLTLSQIRDISRNKLTLELADEAIADINISSGIVQKIIDEGRTVYGINTGFGLLANTKIEDKDLQLLQRSIVLSHAAGTGQYMQDATVRLMMVLKINSLSRGFSGIRLEVINFLIQLVNAEVYPCVPEKGSVGASGDLAPLSHMSLTLLGEGEVSYKGQIMSAKEGLEIAGLEPIELAAKEGLALLNGTQASTALALEGLFNAEDLFAASSVIGAMSVEAAMGSRSPFDPRIHAARGQKGQMDAAGLFRHLLGDESEISLSHVDCEKVQDPYSLRCQPQVLGACLTQIRQAAEVLGTEANGVTDNPLVFQDTGDIISGGNFHAEPVAMAADNLAIALAELGAIAERRIALLIDPNLSKLPPFLVENGGVNSGFMIAQVTAAALASENKTYAHPASVDSLPTSANQEDHVSMATFAARRLRDMSENTRGVLAIELLAAAQGLDFRAPLQPSAAVAKAKAELREVVTYYDKDRFFGPDIEASTDLLLTSSFNSYLPAGILASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP93</accession>
    <name>B1KP93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323012.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0363"/>
    <dbReference type="EnsemblBacteria" id="ACA84663">
        <property type="protein sequence ID" value="ACA84663"/>
        <property type="gene ID" value="Swoo_0363"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0363"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061796_0_0_6"/>
    <dbReference type="OMA" id="VDCKEAR"/>
    <dbReference type="OrthoDB" id="1169054at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="29"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="350" mass="39428" checksum="3AEA74173F169912" modified="2008-04-29" version="1">MSQIKGPGIFLAQFCQDDAPFNNLTSICQWVADLGYKAVQIPTWDKRLFDLKLAYQSQTYCDDVKGIIADTGLSISELSTHLQGQLVAVHPAYDKQFDAFAPEEVKNKPQARAQWAVEQVSMAAKVSQTLGLNAHATFSGALLWQTAYPWPQRPAGLVEEGFKELGKRWLPLLNKFEDAGVDLCYELHPGEDLHDGVTFERFLAATGDHARANILYDPSHFVLQQLDYLAFIDIYHERIKAFHVKDAEFRPNGRSGVYGGYQDWQQRPGRFRSLGDGQIDFKQIFSKLTQYGFDGWAVLEWECCLKHPADGAKEGAPFIEQHLIRTPEYAFDDFASSGVDESLNRSILGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPF8</accession>
    <name>B1KPF8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324457.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1827"/>
    <dbReference type="EnsemblBacteria" id="ACA86111">
        <property type="protein sequence ID" value="ACA86111"/>
        <property type="gene ID" value="Swoo_1827"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1827"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056342_3_0_6"/>
    <dbReference type="OMA" id="HMGDLFF"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766923" evidence="1">
        <location>
            <begin position="26"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="51"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="291" mass="32449" checksum="EA351BABE8816BE9" modified="2008-04-29" version="1" precursor="true">MAHMMNTRLLLSVSLSYLLTTSAFANDDRFKDVEITPQQLTETSYMFTGSGGNIGVSAGSDGILIIDNQFAPLADKISAALSKIQTGKPKYVVNTHYHGDHTGGNNLFGIDGVILAHHNVLSRLSGNTSYTPEGLPSITYHEGINIHFNGENLQLLHMGPGHTDGDSIVLWQDKSVLHMGDLFFKDRFPYIDLNAGGSVKGYRNNVAAMIRKIDDETKVIPGHGSLATRNDLIRFKHMLDASINWMESKLQAQQTLDEIQAEGMPEKWQAWEWRFISEKKWIDTLYNGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPL4</accession>
    <name>B1KPL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324513.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1883"/>
    <dbReference type="EnsemblBacteria" id="ACA86167">
        <property type="protein sequence ID" value="ACA86167"/>
        <property type="gene ID" value="Swoo_1883"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1883"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_8_1_6"/>
    <dbReference type="OMA" id="SDCLFCK"/>
    <dbReference type="OrthoDB" id="1934382at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="99"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="13155" checksum="5D64216256025EFD" modified="2008-04-29" version="1">MAEETIFSKIIRREIPADILFQDELVTAFRDINAQAPSHILIIPNHLIPTVNDVKASDEKALGRMMTVAAKLAEEEGIAEDGYRLIMNCNKHGGQEVYHIHMHLVGGRPLGRMLAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPP6</accession>
    <name>B1KPP6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324545.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1915"/>
    <dbReference type="EnsemblBacteria" id="ACA86199">
        <property type="protein sequence ID" value="ACA86199"/>
        <property type="gene ID" value="Swoo_1915"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1915"/>
    <dbReference type="eggNOG" id="COG0676">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048345_4_0_6"/>
    <dbReference type="OMA" id="TQALHSY"/>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016020">
        <property type="entry name" value="PHexose_mutarotase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="282" mass="31845" checksum="2DFB3CB2EB514D1B" modified="2008-04-29" version="1">MGSVTTKKHANGLEYVDVDTPACKARIFLQGAQIDFFQPTGKAPLLWVSSADDYQAGSGIRGGIPVCWPWFGMNDNSDWPQHGFARTRLWALESVQMKDSGVELRFTLKISEEDKLYWPHDTRVEMLFILNGTLTVSLKNTNLSGYPISFTQALHTYFPIGDISQLKAKGFEGSQYIEFGEGPFKQQGDEVSFDKETDRVYTKLSDLQELVTPEGVIEVNRENSRSAVLWNPWIEKSQRLSRFNSDDYLSMVCLEAANVLDDAVTLAPDESHTLTTKIRWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPQ8</accession>
    <name>B1KPQ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ordered locus">Swoo_3322</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325927.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3322"/>
    <dbReference type="EnsemblBacteria" id="ACA87591">
        <property type="protein sequence ID" value="ACA87591"/>
        <property type="gene ID" value="Swoo_3322"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3322"/>
    <dbReference type="eggNOG" id="COG0026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011534_0_0_6"/>
    <dbReference type="OMA" id="ITFDHEH"/>
    <dbReference type="OrthoDB" id="1165275at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="97"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="138"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="178"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="261"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="41671" checksum="13C59A7351202521" modified="2008-04-29" version="1">MNILVLGAGQLARMMSLEGAPLDLNVRAFDVGSQKIIHPLTHQVFEQSLGQAISMVDVITSEFEHIPDDVLALCCQSGKFYPGKAAIKTGGDRSIEKDLLDKTGVPSAPYQLITEKQHLLDAVSQLDLPLVIKTCQAGYDGKGQWRLKSLDQVDAIWAEMAGFIASGTESFPHTIIAEKMIPFDREVSVIGARDKEGNVKIYPVTENQHTNGVLTLSLAIEMDEKIQQQAVDAFNKLSLSMNYVGVLAIEFFEVSGTLMVNEIAPRVHNSGHWTQQGTACSQFENHLRAVAGLPLGCTQAQKPSVMINVLGQGAIPSQVLTIDDVKSHWYGKTQRAGRKMGHINVSAEDNSALGNKLLQLADMLPEQDYPGVRLTAERLLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT8</accession>
    <name>B1KPT8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MazG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325956.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3352"/>
    <dbReference type="EnsemblBacteria" id="ACA87621">
        <property type="protein sequence ID" value="ACA87621"/>
        <property type="gene ID" value="Swoo_3352"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3352"/>
    <dbReference type="eggNOG" id="COG3956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038356_0_1_6"/>
    <dbReference type="OMA" id="HPHIYGD"/>
    <dbReference type="OrthoDB" id="1099129at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011551">
        <property type="entry name" value="NTP_PyrPHydrolase_MazG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30522">
        <property type="entry name" value="PTHR30522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00444">
        <property type="entry name" value="mazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="29"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="170"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="30172" checksum="1BEE6B90680890C9" modified="2008-04-29" version="1">MQNNDIQPLLDIMAKLRDPQTGCPWDKAQRFETIVPFTLEEAYEVADTIERMAIDELPDELGDLLFQVVFYCQLGKEQGLFDFADVVEKICNKLTSRHPHVFGTLKGASSDEVKENWEQIKAKERSERDLHSILDNIPVGLPALSRSVKIQKRVARVGFDWAELGPVVDKIHEEIDEVIHEVEQEKVNPDKVQDEMGDLLFAVVNLARHLGVEPEQALRGANRKFERRFRGVESLANKAEKPMEEHTLDELDQYWDEVKLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPU2</accession>
    <name>B1KPU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325960.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3356"/>
    <dbReference type="EnsemblBacteria" id="ACA87625">
        <property type="protein sequence ID" value="ACA87625"/>
        <property type="gene ID" value="Swoo_3356"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3356"/>
    <dbReference type="eggNOG" id="COG3068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096082_0_0_6"/>
    <dbReference type="OMA" id="FYGVYPA"/>
    <dbReference type="OrthoDB" id="1327644at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1590.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007338">
        <property type="entry name" value="DUF416"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023381">
        <property type="entry name" value="YP001051499.1-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04222">
        <property type="entry name" value="DUF416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="201" mass="22668" checksum="719F278C3F176174" modified="2008-04-29" version="1">MTTKLGFFKRVKALDFQQKKVFAIALCQRMLPNYQLFSEVCEFGDPQVLDTVLNLLWQSSYDSKLKLNIDIYLERLELNTPDPANFDVYGVYPAMDATTALIALLSALQSKIEEDIVNISKLSSSTVANYIEAISDVELDEEAFDDFIFNHEVMLDEKALQENLLTLIEDNPKLNAEFIKSLRKEIVDAGVSNIGVGMQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPZ3</accession>
    <name>B1KPZ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327423.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4857"/>
    <dbReference type="EnsemblBacteria" id="ACA89106">
        <property type="protein sequence ID" value="ACA89106"/>
        <property type="gene ID" value="Swoo_4857"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4857"/>
    <dbReference type="eggNOG" id="COG0824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101141_2_2_6"/>
    <dbReference type="OMA" id="DMDAMGH"/>
    <dbReference type="OrthoDB" id="1989068at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA89106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="16380" checksum="3DCA422FBB29FF6F" modified="2008-04-29" version="1">MDDFIKQYPIYTEIPVAWGEMDALQHVNNVVYFRYFESARIDFFNQINLFSELQTANIGPVLADNHARYKRPVTYPDTLLVGVTISDVQSDRFMMHYTAFSQAQQAVTTLGSSLVVMFDFKTGKKSKLTGKLLDSLKSHEKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPZ8</accession>
    <name>B1KPZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4862</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327428.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4862"/>
    <dbReference type="EnsemblBacteria" id="ACA89111">
        <property type="protein sequence ID" value="ACA89111"/>
        <property type="gene ID" value="Swoo_4862"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4862"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="LMEEVFQ"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA89111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="280" mass="31419" checksum="0AE06DE7C562020D" modified="2008-04-29" version="1">MDIKLEPLLELCDVTKQFVDKTAISKLSIQLYPGMVVGLLGQNGAGKSTLMRCALGIIEPSSGKITTLGEPVQQLSSEAKTQIGYVPQQPFGYEGFSISRALELHRSFYPEWDKELEREWLQRFDLDTKQQVQRLSVGQRQSLALIMAMAYRPKLLILDEPVASLDPIARRAFMSDLFELAIESGSAVLFSSHITSDLERVASHLALMREGELVLFKEMDSVREEVKLLTLADGEVLEADIRVLNRLGNKVLVDNFCAAQYPDIKSESMNLEQLFMALHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ86</accession>
    <name>B1KQ86_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amino acid-binding ACT domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323090.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0443"/>
    <dbReference type="EnsemblBacteria" id="ACA84741">
        <property type="protein sequence ID" value="ACA84741"/>
        <property type="gene ID" value="Swoo_0443"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0443"/>
    <dbReference type="eggNOG" id="COG3978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183627_0_0_6"/>
    <dbReference type="OMA" id="RGFQICS"/>
    <dbReference type="OrthoDB" id="2080824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="1">
        <location>
            <begin position="4"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="84" mass="9726" checksum="8BB84F2C2D1C6ADE" modified="2008-04-29" version="1">MKHTVNLTLEQRPEVLERVLRVVRHRGFKVTKMNMSLESEKVADLDMTVESERAIELLTKQLDKLVDVLSCNASEHRVPERLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD4</accession>
    <name>B1KQD4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Outer membrane adhesin like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323138.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0491"/>
    <dbReference type="EnsemblBacteria" id="ACA84789">
        <property type="protein sequence ID" value="ACA84789"/>
        <property type="gene ID" value="Swoo_0491"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0491"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_223070_0_0_6"/>
    <dbReference type="OMA" id="GNWSIDL"/>
    <dbReference type="OrthoDB" id="413616at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="35"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044016">
        <property type="entry name" value="Big_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041339">
        <property type="entry name" value="Ig-like_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040853">
        <property type="entry name" value="RapA2_cadherin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18200">
        <property type="entry name" value="Big_11"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19077">
        <property type="entry name" value="Big_13"/>
        <property type="match status" value="33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17803">
        <property type="entry name" value="Cadherin_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Cadherin" evidence="6">
        <location>
            <begin position="5775"/>
            <end position="5873"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="6617"/>
            <end position="6742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="7120"/>
            <end position="7149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="7120"/>
            <end position="7139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="7149" mass="732321" checksum="3E36BBBB9CE1CA20" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQF2</accession>
    <name>B1KQF2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Fumarate reductase iron-sulfur subunit</fullName>
            <ecNumber evidence="3 6">1.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>a menaquinone + succinate = a menaquinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:27834"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="6">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.4" evidence="3 6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323155.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0510"/>
    <dbReference type="EnsemblBacteria" id="ACA84807">
        <property type="protein sequence ID" value="ACA84807"/>
        <property type="gene ID" value="Swoo_0510"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0510"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_3_3_6"/>
    <dbReference type="OMA" id="KYDPLVW"/>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102040">
        <property type="term" value="F:fumarate reductase (menaquinone)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="144"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="243" mass="27337" checksum="180DB6D68CDE277E" modified="2008-04-29" version="1">MSQGRTLTFNIFRYDPQVSGDKPKMVKYQIEETPGMSVFIALNLLREQQDSSLQFDFVCRAGICGSCAMVINGFPTLACRTLTSKYPQGEITLMPLPGFELIGDLSVNTGKFMRELAERLKLWLHPDQDDVDVHRLEAPMAPEEAARLYELERCVECGVCVSACATKQMRETFVGAVGMMKLARFELDSRDTRSVEDFYHVIGNQDGVFGCMTLLGCQDNCPKDLPHMQQIAYLRRKMAVALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH3</accession>
    <name>B1KQH3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1928</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324558.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1928"/>
    <dbReference type="EnsemblBacteria" id="ACA86212">
        <property type="protein sequence ID" value="ACA86212"/>
        <property type="gene ID" value="Swoo_1928"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1928"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031786_2_1_6"/>
    <dbReference type="OMA" id="GYAGHIE"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010964">
        <property type="entry name" value="M20A_pepV-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01887">
        <property type="entry name" value="dipeptidaselike"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005661730" evidence="3">
        <location>
            <begin position="23"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="M20_dimer" evidence="4">
        <location>
            <begin position="290"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="508" mass="55655" checksum="854CC0A1F199F10F" modified="2008-04-29" version="1" precursor="true">MKTLIGTLSLLLGVMLAFSVQALSPKSESVADYAVENYEDAMLDSLAKLVTFKTVAKEGMTPENNPEFIGFKQEIKKLTQELGLTYSDHGYVLLIGLGDSEDKLGVITHGDVQPADPALWAQDPFLLDTQSQPGKLIGRGTEDDKGAIVTAMYAMKSIKDKQLTLSKRIELMVYLAEESDWDPLREFLKGYTPAEINITIDAEYPVVTAEKGWSQITFTIPNLDGELIGKSHDKHSANLLSFSGGYFSSQIPQQAKASLSNVSSPLLAKLKTIVTKQEGMAYRFESKGEHLTIFADGKAAHSSSPKDGVNAVTHLAQLLSAHHWPKSQASLTQSFIHELIGLGVEAELFGDIAYNDGFMGPMTLAPTVVKQTQKGTEVTLNLRRPVGKTPELLDIQTAQALELWQVKHDIKLKDVETYWGKPMVMGNAPHLDTLLAVFSHFTGIKDPKPVSIGGSTNSKLFPNALSFGPTMPGKAYTGHTENEFMTQKQFMLNLKMYTAAFIELAVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH7</accession>
    <name>B1KQH7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-hydroxyphenylpyruvate dioxygenase</fullName>
            <ecNumber evidence="7">1.13.11.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1932</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.27" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324562.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1932"/>
    <dbReference type="EnsemblBacteria" id="ACA86216">
        <property type="protein sequence ID" value="ACA86216"/>
        <property type="gene ID" value="Swoo_1932"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1932"/>
    <dbReference type="eggNOG" id="COG3185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034004_1_0_6"/>
    <dbReference type="OMA" id="DAQFAFE"/>
    <dbReference type="OrthoDB" id="402639at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="12"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="155"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="346" mass="39539" checksum="CCB2886A56D5AB88" modified="2008-04-29" version="1">MASEQNPLGLLGIEFTEFATPEHDFMHQVFIDFGFSKLKKSKTKDIAYYKQNDINFLLNNERSGFSSEFAKSHGPAICSMGWRVEDAKFAFEGAVERGAKPADEASKDHPYPAIYGIGDSLIYFIDIFGEENNIYKHDFVDLENPVVTQEKGFIEVDHLTNNVYKGTMEKWANFYKDIFGFTEVRYFDIKGSQTALVSYALRSPDGSFCIPINEGKGNDKNQIDEYLRDYDGPGVQHLAFRSRDIVASLDAMEGSSIQTLDIIPEYYETIFDKLPQVTEDRERIKHHQILVDGDEDGYLLQIFTKNLFGPIFIEIIQRKNNLGFGEGNFTALFQSIERDQQRRGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQK8</accession>
    <name>B1KQK8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CheB methylesterase</fullName>
            <ecNumber evidence="3">3.1.1.61</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.61" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324593.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1963"/>
    <dbReference type="EnsemblBacteria" id="ACA86247">
        <property type="protein sequence ID" value="ACA86247"/>
        <property type="gene ID" value="Swoo_1963"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1963"/>
    <dbReference type="eggNOG" id="COG2201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_51_2_6"/>
    <dbReference type="OMA" id="PGYHLSV"/>
    <dbReference type="OrthoDB" id="1655418at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="199" mass="21720" checksum="CC0BE1904C3702CE" modified="2008-04-29" version="1">MFEALVVGVSAGGLRALTEILPKLPKGYPLAILIVQHRHRDSDNFLTEHLNELSSVCVKEAELREAILPAHVYIAPAGYHLLVERDKTLSLSIDPPVNFSIPSIDVLFQSAATCYKNRLVGLILTGANSDGSQGLKFVKDYGGFAIVQAPNTAEVDVMPRAAIDLVDVDKVVPLEELAAFLTQARFKQNSTVVREKLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQL3</accession>
    <name>B1KQL3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324598.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1968"/>
    <dbReference type="EnsemblBacteria" id="ACA86252">
        <property type="protein sequence ID" value="ACA86252"/>
        <property type="gene ID" value="Swoo_1968"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1968"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_2_2_6"/>
    <dbReference type="OMA" id="TEIDFCG"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="267" mass="29967" checksum="6887A6BEF17D5F64" modified="2008-04-29" version="1">MKIKIDIIDAFTDVRFKGNSAAVIITDTWLPDELMQSIAIENNLSETAFVKRLNTQDYQIRWFSPITEIDFCGHATLAASFVIFKEHKGLEEIRFTAKAVGEVVITKSYDSYIQMSFPNRMPQKLKSVPTALIEGLSIKPVDVLRNEQAYVVVYRDSCDVISVEKDDEILKRLAPFDVVVTAKGNNVEGEYDFISRYFWPANGGGEDPVTGSIHTGLAPYWSARLDKNELKAYQASARGGELLCRVDGERVYISGKAVQYLEGVIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQL4</accession>
    <name>B1KQL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324599.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1969"/>
    <dbReference type="EnsemblBacteria" id="ACA86253">
        <property type="protein sequence ID" value="ACA86253"/>
        <property type="gene ID" value="Swoo_1969"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1969"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060397_0_1_6"/>
    <dbReference type="OMA" id="CGFCLPY"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="47"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="214" mass="24600" checksum="DC802F2952A40C44" modified="2008-04-29" version="1">MDKYKLSVNTFNKFAQKYQDKYMDLSLYDDTFELFCQLINQKVCPEIFEIACGPGNISRFLIERCDEMKLHGIDLAPNMVTLAKENNPNGYFEVMDCRDISQIDHLYDAIMCGFCLPYISREDAETLIKNSAKLLKKEGVIYLSTMEGEYTKSKLDTSSNGDQMYTHYHSAEHLCEHLESNGFTVLDIKRKTISEQSDTSINDLFIIAKWGLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQS6</accession>
    <name>B1KQS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326017.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87682">
        <property type="protein sequence ID" value="ACA87682"/>
        <property type="gene ID" value="Swoo_3414"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3414"/>
    <dbReference type="HOGENOM" id="CLU_2119457_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765132" evidence="1">
        <location>
            <begin position="33"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="12581" checksum="806D238948B4E0D7" modified="2008-04-29" version="1" precursor="true">MSENTMSRRKAIKLMGNVTAAGIVLSSTSVSASSALLSGGADTASLNGEEYLAHLLSRKFANSKQVTQAEIKLFSKRYIEHQGEKFDPRVNLKTPLDELNLMREFVMSVKYRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQV1</accession>
    <name>B1KQV1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326042.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3439"/>
    <dbReference type="EnsemblBacteria" id="ACA87707">
        <property type="protein sequence ID" value="ACA87707"/>
        <property type="gene ID" value="Swoo_3439"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3439"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_5_2_6"/>
    <dbReference type="OMA" id="CPAPSHM"/>
    <dbReference type="OrthoDB" id="1677723at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="136" mass="15198" checksum="07E773EAB3A32A1F" modified="2008-04-29" version="1">MDIAEVAKATGLPASTLRYYEEKGLIRSSGRNGLRRTYHPKVIEQLALISLGRNAGFSLDEIGKMFTAEGPDINRKLLLAKADELDRKIEELATMSKGLRHAAACKVPNQLDCPKFLRILRIAGKNRSRHSNILKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ4</accession>
    <name>B1KQZ4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endo/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326084.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3484"/>
    <dbReference type="EnsemblBacteria" id="ACA87750">
        <property type="protein sequence ID" value="ACA87750"/>
        <property type="gene ID" value="Swoo_3484"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3484"/>
    <dbReference type="eggNOG" id="COG4222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042670_0_0_6"/>
    <dbReference type="OMA" id="VRFATFN"/>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767310" description="Endo/exonuclease/phosphatase domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="42"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="464" mass="51110" checksum="43710601A76F88CA" modified="2008-04-29" version="1" precursor="true">MKLLKTAAAAAISMALLAGCNDETIINNPVEPTPDATNVRFATYNLSFDRATFEDLVSEMQITAPEQEVLMQGWFDKTLTDDELKVAEKVIQIRNVAAVIQTERPAVLMMGEFNNDGIAENQDAIKGFRLNYLAVPQNALGTTADDKKMLEPIQFAYFENFSTNTGLLSEFDLDRNGKVALPGDAWGFGFYHGQYAFGLLSQYPIDTDNIRTFQNFKWKDMPGETNPTITNCDDDKNPIPTGMKCGDEWYTAEAWAEKPLSSKNHVDAPILIPTADGEKVVHLLLSHPTPPVFDTVTENNKLLNRAEIAFWNDYVAGADYIYDDAGNKGGLGLDASFVVMGDLNADPENGDGFLDAIQDLMNHDRVNTLATDGVYAPNSLGSTECVALGDCGDSTYPDRITSTFGLRVDHAIPSNDLNIIDSGVFWPATFEEGRLLMNDERVGKYGNGKDISSDHRLVWIEAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR23</accession>
    <name>B1KR23_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Biotin carboxylase</fullName>
            <ecNumber evidence="5 13">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Swoo_0544</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="5 13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323188.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0544"/>
    <dbReference type="EnsemblBacteria" id="ACA84840">
        <property type="protein sequence ID" value="ACA84840"/>
        <property type="gene ID" value="Swoo_0544"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0544"/>
    <dbReference type="eggNOG" id="COG0439">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_2_6"/>
    <dbReference type="OMA" id="FVEICSH"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0092">Biotin</keyword>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="15">
        <location>
            <begin position="5"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="124"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA84840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="452" mass="49490" checksum="DD32215C456CE1E1" modified="2008-04-29" version="1">MKPEPLKRVLIANRGEIALRVQRACSQLGIETVAVHSTADRDQLHLRHASNTICIGKPAPIDSYLNIPAIISAAAQAKADAIHPGYGFLSENADFAEQVQRSGFTFIGPNADVIRKMGDKVSAISAMKKVGVPTVPGSDGVLTQDNKLNQQIAEKIGYPIIVKATAGGGGKGMRVVHHSDELIQAIELTQAEAKAAFANGDLYMEKYLQHPRHIEIQVLSDGQGNAIHLGERDCSMQRRHQKVLEEAPALEIDSATRSKIGKLCANACIEIGYRGAGTFEFLFEAGEFYFIEMNTRIQVEHPITEMITGIDLIHAQLEIASGRALTIKQQDIQLNGHSIECRINAEDPHTFTPSPGTITGFHAPGGIGVRWDSHLYSGYTVPPYYDSMIGKLITWGTTRDQAIARMQTALDELTIEGISTNQALLQQILKDRGFREGGQSIHYLEKQVLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR54</accession>
    <name>B1KR54_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Oxidoreductase FAD/NAD(P)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0575</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323219.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0575"/>
    <dbReference type="EnsemblBacteria" id="ACA84871">
        <property type="protein sequence ID" value="ACA84871"/>
        <property type="gene ID" value="Swoo_0575"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0575"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_7_0_6"/>
    <dbReference type="OMA" id="PGRWRWY"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="88"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="321" mass="36115" checksum="F2CD0B272271A5EC" modified="2008-04-29" version="1">MKQIHWQEKAITLNQDESVLEALLRQGIDLAYSCKNGNCHTCMLQAKKGDVQDAQPDIRESWKALGYFLPCICFPQGELTVSPITQQALFSQVKVAAITPLSKRILSITLDPDTPLEYHAGQFINLRRSDGLTRSYSLASHPAQGDMLEIHVQRIDNGGMSQWIHEQLSLDDKLELCGPFGHCYYQKEMQTMPMLLVGTGSGLAPLLGIVKDALHHQHQGPIHLYHGSRTADDLYAQQLLTSLARQYDNLHYLGCVSGTQAEEKDRIRADELALKNHQNLSGWQVYLCGHPDMVNKMKKRTYLAGADIKNIFADPFIHKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR55</accession>
    <name>B1KR55_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Group 1 truncated hemoglobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="3">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the truncated hemoglobin family. Group I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323220.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0576"/>
    <dbReference type="EnsemblBacteria" id="ACA84872">
        <property type="protein sequence ID" value="ACA84872"/>
        <property type="gene ID" value="Swoo_0576"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0576"/>
    <dbReference type="eggNOG" id="COG2346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103526_2_1_6"/>
    <dbReference type="OMA" id="HQKAFLT"/>
    <dbReference type="OrthoDB" id="1697277at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016339">
        <property type="entry name" value="Hemoglobin_trunc_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002030">
        <property type="entry name" value="Globin_Protozoa/Cyanobacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="binding site" description="proximal binding residue" evidence="3">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR002030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR002030-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="121" mass="13352" checksum="2C5B641084DA2720" modified="2008-04-29" version="1">MTTLFEQLGGNASVDAAVDIFYRKVLSDDSISHFFDDVDMDRMRAMQKSFLTMAFGGPNDYTGNSLREAHAPLLEQGLDTNHFNTVAGHLQATLKELNVSDELIEQVMTIAASTHDDVLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR59</accession>
    <name>B1KR59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323224.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0580"/>
    <dbReference type="EnsemblBacteria" id="ACA84876">
        <property type="protein sequence ID" value="ACA84876"/>
        <property type="gene ID" value="Swoo_0580"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0580"/>
    <dbReference type="eggNOG" id="COG4968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1766765_0_0_6"/>
    <dbReference type="OrthoDB" id="1986406at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="16361" checksum="BD889A0947B03AA9" modified="2008-04-29" version="1">MKNQSGFTLIEMIISIIVIGILAVVALPRFIHISDDAKIAVADGMAASFESSIKPASSKHVIENKKGFIVIDGSIVSFRSDNEIKSYPQAGDSRACAELWNKLTEGERASDFEDEYIHSVFYEKTCEYSIEEQIFTYNNNSGEVVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR68</accession>
    <name>B1KR68_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323233.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0589"/>
    <dbReference type="EnsemblBacteria" id="ACA84885">
        <property type="protein sequence ID" value="ACA84885"/>
        <property type="gene ID" value="Swoo_0589"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0589"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046130_1_1_6"/>
    <dbReference type="OMA" id="LNRWHLM"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="211"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="422" mass="46011" checksum="67D748F9488D70EC" modified="2008-04-29" version="1">MLKGVSPQLFANLSASDQLASLRILGLVLKLVLTFMAAETFGLSLHSPALNYALILEAVYLAVTFGVRKPLQLTDTGLFIALLLDTAFWITWLYFSGGATNAFISLLLLPIAIAAVILPRWAPWTLTLISTLAYSLMLYTVPSEQMQHHGMDMGSHYLGMWLNFVISSLVLTTSVAFIANRMRRQDAELAYMREAQLRQEKLLALGTASAQMAHQLATPLSSLRLLVEEVAEESDANMPAIKEMNSALSRCEKTLADLRLATESIREQKQLKITAGELINQLEQQVTLLMPQVLLELESDAQADVIQVQSDTSLLPAVLSLIENAARASDEQTASQRVKITLDIDSEQACIILRVRDYGCGIPQGVISQLGHKFVESPTGMGVALMLSHASFERLGGRLILGAHLEGGAVAEVSLPIAESVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRA8</accession>
    <name>B1KRA8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324661.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2031"/>
    <dbReference type="EnsemblBacteria" id="ACA86315">
        <property type="protein sequence ID" value="ACA86315"/>
        <property type="gene ID" value="Swoo_2031"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2031"/>
    <dbReference type="eggNOG" id="COG0659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_7_0_6"/>
    <dbReference type="OMA" id="WSNIFRK"/>
    <dbReference type="OrthoDB" id="967266at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015116">
        <property type="term" value="F:sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="420"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="518" mass="55350" checksum="5D579054F87081E9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD7</accession>
    <name>PDXH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="1">1.4.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">PNP/PMP oxidase</fullName>
            <shortName evidence="1">PNPOx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Pyridoxal 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pdxH</name>
        <name type="ordered locus">Swoo_2060</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15817"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15149"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="1">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324689.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRD7"/>
    <dbReference type="SMR" id="B1KRD7"/>
    <dbReference type="STRING" id="392500.Swoo_2060"/>
    <dbReference type="EnsemblBacteria" id="ACA86344">
        <property type="protein sequence ID" value="ACA86344"/>
        <property type="gene ID" value="Swoo_2060"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2060"/>
    <dbReference type="eggNOG" id="COG0259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032263_2_3_6"/>
    <dbReference type="OMA" id="PEPNAMV"/>
    <dbReference type="OrthoDB" id="1542844at2"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0288">FMN</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000186342" description="Pyridoxine/pyridoxamine 5'-phosphate oxidase">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="8"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="62"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="77"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="141"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="192"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01629"/>
        </source>
    </evidence>
    <sequence length="213" mass="24397" checksum="4D1416CDAA587A0F" modified="2008-04-29" version="1">MSKLSDIRREYSLGDLHRDALPDEPMSLFSKWMEEARDSELLSDPTAMSIATVDESGQPFQRIVLLKRFSEEGFVFFTNLESRKSQQIAHNAKVSLLFPWHSLERQVAITGEAEALSTADVMKYFITRPKESQIAAWVSQQSSKISARQVLETKYAEMKAKFSKGEVPLPKFWGGYLVKPSSIEFWQGGERRLHDRFLYDKGQSGWDISRLAP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG9</accession>
    <name>HIS1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="1">ATP-PRT</shortName>
            <shortName evidence="1">ATP-PRTase</shortName>
            <ecNumber evidence="1">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisG</name>
        <name type="ordered locus">Swoo_2092</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324721.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRG9"/>
    <dbReference type="SMR" id="B1KRG9"/>
    <dbReference type="STRING" id="392500.Swoo_2092"/>
    <dbReference type="EnsemblBacteria" id="ACA86376">
        <property type="protein sequence ID" value="ACA86376"/>
        <property type="gene ID" value="Swoo_2092"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2092"/>
    <dbReference type="eggNOG" id="COG0040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038115_1_0_6"/>
    <dbReference type="OMA" id="YVMMDYD"/>
    <dbReference type="OrthoDB" id="1419568at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000092752" description="ATP phosphoribosyltransferase">
        <location>
            <begin position="1"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <sequence length="299" mass="33141" checksum="0A1591CA837F6245" modified="2008-04-29" version="1">MSESNRLRIAIQKSGRLSKESMKLLRSCGVKFNINEQRLIAHSDNLPIDLLRVRDDDIPGLVMDGVVDLGIIGENVLEEEQIERERLDKPASCIKLRELDFGACRLSLAVPNEFNYEDASSLEGLRIATSYPNLLRRYMQRKGITYNDCMLKGSVEVAPRAGLADGICDLVSTGATLEANGLYETEVIYRSNACIIQSSEVQLPAKQALIEKILSRINGVVRAKESKYILLHAPTETLEQIVALLPGAENPTVLPLNDDTNRVAIHAVSTEDLFWDTMEELTKLGASSILVMPIEKMMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK9</accession>
    <name>B1KRK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326107.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3510"/>
    <dbReference type="EnsemblBacteria" id="ACA87774">
        <property type="protein sequence ID" value="ACA87774"/>
        <property type="gene ID" value="Swoo_3510"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3510"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_50_6"/>
    <dbReference type="OMA" id="ACYSEND"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="111"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="248"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="504" mass="57383" checksum="7E5B5AB849B01C13" modified="2008-04-29" version="1">MDIGWYLVLLLIVCIAGIIFWYRHRRGEAKFIHALLQQIELLKSKEGALNLGDIPPEQLTQLDVPKKYLSLYCAWRQFINGLPVPNDKDKLTGLANRLGLKSRFLTLMPITQGTLVLIDIYQFRFVNDLFGFSVGDKLLQILSERLQGEGNNVSFLARMNEDEFLLYFEQAQDEAKLLAIREKLQMPFNIQDIPITVQIQMGYLDLAQHHTYVSQLLRRLDLALIKAKEDKQLFASYSEGDDLSQQRQLGIINRLPKALARGELYMVYQPKLDVLNGGFSQVEALIRWEHEDLGMVSPAEFIPLAEYAGMIGLVSEWALDQVISQQYKWHQSGLLLQVAVNLSSKDIISSTLCDDIQMKFDKYGLETKLLSIEITESKLMDDMEMAVETIEKLKAIGVDVAIDDFGTGHSSLAYLKYFPVDEVKIDKAFIDELMSDKHAKHIMKSSIELAKGLDFKVTVEGVETEEVKSLLVEMGVDKIQGDLFAKPMSALELEVNWQQLQLRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRR2</accession>
    <name>RIMP_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rimP</name>
        <name type="ordered locus">Swoo_3563</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RimP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326160.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRR2"/>
    <dbReference type="SMR" id="B1KRR2"/>
    <dbReference type="STRING" id="392500.Swoo_3563"/>
    <dbReference type="EnsemblBacteria" id="ACA87827">
        <property type="protein sequence ID" value="ACA87827"/>
        <property type="gene ID" value="Swoo_3563"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3563"/>
    <dbReference type="eggNOG" id="COG0779">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070525_1_1_6"/>
    <dbReference type="OMA" id="YIHVSLY"/>
    <dbReference type="OrthoDB" id="1595498at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01734">
        <property type="entry name" value="YlxS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036847">
        <property type="entry name" value="RimP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17384">
        <property type="entry name" value="DUF150_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74942">
        <property type="entry name" value="SSF74942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="chain" id="PRO_1000136794" description="Ribosome maturation factor RimP">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <sequence length="151" mass="16656" checksum="5E5D53B6A747C81B" modified="2008-04-29" version="1">MATIENRLEEMLKSPVEALGHTLWGLEYIQAGKHSVVRVYIDNEKGVFIEDCAEVSRQVSAVLDVEDPISTEYTLEVSSPGVDRPLFNAEQYTAYIDETVKIQLTMPVAGSRNLKGTVTGVEGQMLTLTVDGNELIIALDNIRKGNLIAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRS0</accession>
    <name>B1KRS0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ordered locus">Swoo_3571</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3571"/>
    <dbReference type="EnsemblBacteria" id="ACA87835">
        <property type="protein sequence ID" value="ACA87835"/>
        <property type="gene ID" value="Swoo_3571"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3571"/>
    <dbReference type="eggNOG" id="COG0341">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050012_1_0_6"/>
    <dbReference type="OMA" id="FMAIVVY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="314" mass="34208" checksum="5620CBC7E3A25145" modified="2008-04-29" version="1" precursor="true">MNINMMNGKSWNFSNMSRLTKWRYFTSFISLTLMILSVTIISVKGFNWGLDFTGGVVTEIRVDKEISAKQIEVLLAKSSQQEVSVISAGELGRWVLRYSQTPTSGDVSANALDITEVLSPLKSEVQVLNTSIVGPQIGQELAEQGGLALLVAMLCILGYLSFRFEWRLASGALFALFHDVIFVLAFFSLTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLTLKPKMPIADVCTSAVKATFSRTMVTSGTTLMTVSALWVMGGGALESFSIAMFIGILTGTWSSISVGTCLPELFGVNSEHYKLVPVSDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD10</accession>
    <name>B1KD10_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322706.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0056"/>
    <dbReference type="EnsemblBacteria" id="ACA84357">
        <property type="protein sequence ID" value="ACA84357"/>
        <property type="gene ID" value="Swoo_0056"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0056"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063353_0_0_6"/>
    <dbReference type="OMA" id="MRRCPLC"/>
    <dbReference type="OrthoDB" id="1730305at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="25402" checksum="F3B77497A722443E" modified="2008-04-29" version="1">MHRCPLCHNTDTSLFHRNKKRDMYTCSHCQLIFSDATSHLPPQVEKNRYLESNRKKQAALTQFLISLIAQCEQGSSAPLSGLNFGRVLDSSSLSSTGLHQHHIEQYDPFFAPDHHLLKQHYDYICCYKVFEHFRFPFKEWSLLGTMLKPGGWLAISTKLLTDIHSFDKWHHKNNLTHVSFYQRSTFEYLAEQAGFKLLFAANDLILVQKPSGSDITRGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD29</accession>
    <name>B1KD29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xanthine/uracil/vitamin C permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326197.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3600"/>
    <dbReference type="EnsemblBacteria" id="ACA87864">
        <property type="protein sequence ID" value="ACA87864"/>
        <property type="gene ID" value="Swoo_3600"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3600"/>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024508_0_1_6"/>
    <dbReference type="OMA" id="RKGSYFF"/>
    <dbReference type="OrthoDB" id="558559at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026033">
        <property type="entry name" value="Azg-like_bact_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005353">
        <property type="entry name" value="PbuG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="429" mass="45245" checksum="5871920796390D12" modified="2008-04-29" version="1">MLERLFKLKENQTNIKQEMVAGLTTFLTMAYIIFINPKMLADAGMDHGAVFVATCLAAAIGCLIMGFVANYPIALAPGMGLNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVKIREWVVNSIPMSLRLGIAAGIGLFLALIGLKSAGIVVASPATLVTMGDITAFPAVMAMLGFFLIIAMVHRGMKSAVIVSILAVTLLGVVFGDVQYQGVVSLPPSVMPTFMKMDLSNVLEISMLSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSTATITGAMLGTSTTTSYIESTAGVSAGGRTGLTAVVVGILFLLALFISPLAGMVPAYATAGTLFYVAILMMSGLMHVAWEDLTEAAPVVVVCILMPLTFSIATGIALGFISYAVIKLMSGRYKDLSVGVVILAVLFIGKFMYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD81</accession>
    <name>B1KD81_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326249.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3654"/>
    <dbReference type="EnsemblBacteria" id="ACA87916">
        <property type="protein sequence ID" value="ACA87916"/>
        <property type="gene ID" value="Swoo_3654"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3654"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_9_3_6"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764299" evidence="4">
        <location>
            <begin position="25"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="55"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="6">
        <location>
            <begin position="391"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="489" mass="54338" checksum="52523CA717D0038B" modified="2008-04-29" version="1" precursor="true">MTMNTRKTALCSVLVPIIIGLLQACSPTNESVTSQVVAIATEPGPESVEKAQKQPNILLLFADDLGWTDLGYRTARWDTPNIDSLKNQSLEFTRAYVASPTCSPSRASVITGQHPARLKMPRHIPDGKTELGFDKFHRATKEFHLLPTDPAQEPSRNYLPLEVTSIAEAVKPLGYYTAFSGKWHLGSEDYFPIKQGFDEQFGVSTAGHPKSYHAPFWEAYRNPYPDAPKGKNLTERLTDDVVNFINGYDKDQPFMLTNFYYSVHTPHQGPKAATQKYLDRGLDKRYANFGSMVESLDTSVGRILQALEDSGQADNTVVIFYSDQGGYFTNAPLRGGKIGGRALYEGGARVPLIVRWPGVTPNSQISEQLVLSTDILPTFVDIAGGDPSSFKELDGESIVPMLKGEVSSREHVILYRNYEDAYAAVIGKRWKLVAFVSGKTELYDLLTDPAETTDISKQQPERVAQLKQTLLEWQMDVGVNPILKRPDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD2</accession>
    <name>B1KDD2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323280.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0637"/>
    <dbReference type="EnsemblBacteria" id="ACA84933">
        <property type="protein sequence ID" value="ACA84933"/>
        <property type="gene ID" value="Swoo_0637"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0637"/>
    <dbReference type="eggNOG" id="COG2234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019932_0_1_6"/>
    <dbReference type="OMA" id="FNGTHED"/>
    <dbReference type="OrthoDB" id="1465483at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M28" evidence="1">
        <location>
            <begin position="129"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="352" mass="39084" checksum="1F2034C803405337" modified="2008-04-29" version="1" precursor="true">MSPTQIKLISLRFSFTLSILLLFSLTLSGCSTFSTSCKTQLKANWVDQQALKADLAQLTSAKFEGRKTGTQGAALTRDYLNERFTQIGLTPWQSAQADTKTTTQQSKNTDKFNLPFTYSQGFSERKGSNVVGVLKASNPSTSWRLVIAHYDHLGVKGRKIYPGADDNASGIAAMLQLANYAATHPELFTKTNLMFVATDAEEPGLYGGYALAELLSQQNITPNNKQIELAINLDMIGRPERSMVVYLEGRRGFSQFPLIKQKLINETGLCIKAKHPRKRGQLTGNIDWLRASDHYPLHKVGVPWLYFGVPPHQDYHAPSDTQEKIDFEFLAAVTSSAHQLLIIDSLQLGNIQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDN5</accession>
    <name>FABA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Beta-hydroxydecanoyl thioester dehydrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Trans-2-decenoyl-[acyl-carrier-protein] isomerase</fullName>
            <ecNumber evidence="1">5.3.3.14</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabA</name>
        <name type="ordered locus">Swoo_2148</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(3R)-hydroxydecanoyl-[ACP] = (2E)-decenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41860"/>
            <dbReference type="Rhea" id="RHEA-COMP:9638"/>
            <dbReference type="Rhea" id="RHEA-COMP:9639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78466"/>
            <dbReference type="ChEBI" id="CHEBI:78467"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2E)-decenoyl-[ACP] = (3Z)-decenoyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:23568"/>
            <dbReference type="Rhea" id="RHEA-COMP:9639"/>
            <dbReference type="Rhea" id="RHEA-COMP:9927"/>
            <dbReference type="ChEBI" id="CHEBI:78467"/>
            <dbReference type="ChEBI" id="CHEBI:78798"/>
            <dbReference type="EC" id="5.3.3.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioester dehydratase family. FabA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="1"/>
    <dbReference type="EC" id="5.3.3.14" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324777.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDN5"/>
    <dbReference type="SMR" id="B1KDN5"/>
    <dbReference type="STRING" id="392500.Swoo_2148"/>
    <dbReference type="EnsemblBacteria" id="ACA86432">
        <property type="protein sequence ID" value="ACA86432"/>
        <property type="gene ID" value="Swoo_2148"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2148"/>
    <dbReference type="eggNOG" id="COG0764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097925_0_0_6"/>
    <dbReference type="OMA" id="FDCHFKG"/>
    <dbReference type="OrthoDB" id="1379832at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034017">
        <property type="term" value="F:trans-2-decenoyl-acyl-carrier-protein isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01287">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00405">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010083">
        <property type="entry name" value="FabA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272:SF8">
        <property type="entry name" value="PTHR30272:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01749">
        <property type="entry name" value="fabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword id="KW-0276">Fatty acid metabolism</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000201220" description="3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00405"/>
        </source>
    </evidence>
    <sequence length="171" mass="18848" checksum="79296C2F05638424" modified="2008-04-29" version="1">MSKANSFNKEDLIACGHGELFGEHSPRLPIDNMLMIDRITKINADGGEFGKGEIVAELDINPELWFFKCHFDGDPVMPGCLGLDALWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPDAKKVTYKLTVKRKVYRKLVMGIADAVMEVDGREIYSATDLKVGIFKDTSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDT8</accession>
    <name>B1KDT8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324829.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86485">
        <property type="protein sequence ID" value="ACA86485"/>
        <property type="gene ID" value="Swoo_2203"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2203"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_6_1_6"/>
    <dbReference type="OMA" id="ETNQRMS"/>
    <dbReference type="OrthoDB" id="1633707at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06150">
        <property type="entry name" value="YjgF_YER057c_UK114_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035709">
        <property type="entry name" value="YoaB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47328">
        <property type="entry name" value="PTHR47328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="13342" checksum="E1F4673EA0DF0542" modified="2008-04-29" version="1">MDIQRLNPTPRWSDATVFNHMAHFVEIANDTSADVREQVKQIFAQAESTLSQVNSNKSRILSATIYVTDFSHMQQLNEEWEAWLPQGCAPSRACVKVELADPSYLVEISFVAAVITAQS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDU6</accession>
    <name>ISPE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="1">CMK</shortName>
            <ecNumber evidence="1">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ispE</name>
        <name type="ordered locus">Swoo_3688</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326280.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDU6"/>
    <dbReference type="SMR" id="B1KDU6"/>
    <dbReference type="STRING" id="392500.Swoo_3688"/>
    <dbReference type="EnsemblBacteria" id="ACA87948">
        <property type="protein sequence ID" value="ACA87948"/>
        <property type="gene ID" value="Swoo_3688"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3688"/>
    <dbReference type="eggNOG" id="COG1947">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053057_3_0_6"/>
    <dbReference type="OMA" id="RWPSPAK"/>
    <dbReference type="OrthoDB" id="1938933at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000092115" description="4-diphosphocytidyl-2-C-methyl-D-erythritol kinase">
        <location>
            <begin position="1"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <sequence length="284" mass="31233" checksum="26C36286FFCAC485" modified="2008-04-29" version="1">MSNQLSLGWPAPAKLNLFLHVNHRREDGYHELQTLFQFISHGDLLDFKVTDDGSLKLHSNIGNVVADSDNLILRAAKLLQERTATEKGAEIWLDKRLPMGGGIGGGSSDAATCLIALNALWQTHLSRDELAELGLALGADVPVFINGLSAFAEGVGEKLIQVSPKEYWYLVLVPDVHVSTAEIFQDPDLPRNTPKLDLDSLMSSPWRNDCQELVVKRYPQVAKTLDWLIEYAPSRMTGTGACVFGEFEQQQQAQDALAQLPSNMTGFVAKGTNISPLELRLAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE61</accession>
    <name>B1KE61_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323394.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0752"/>
    <dbReference type="EnsemblBacteria" id="ACA85047">
        <property type="protein sequence ID" value="ACA85047"/>
        <property type="gene ID" value="Swoo_0752"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0752"/>
    <dbReference type="eggNOG" id="ENOG503374U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105436_0_0_6"/>
    <dbReference type="OMA" id="GYPMKTW"/>
    <dbReference type="OrthoDB" id="1735190at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764331" evidence="1">
        <location>
            <begin position="19"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="25843" checksum="CAC4FF3BD3F08D04" modified="2008-04-29" version="1" precursor="true">MKKYLALVLLLTSPYLFADDWPEVEFPDTAEVQVVADSMLYHGYPMKTWVMEDEQSQMMIASFFKKQWEEKSERFDAQMFNGDYVINSMQPPFLLTARIHQEYDRVITYVGVTKNVTDRQLEKNNQVQFPKPNGSTLISDIKSNDIFKQGRTLILSTPNSLASSYHFYRRHFQQRGWVENSAILDTQSGKAALQMSQGSNLVDISFNTKKSVIYIVANQVKEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE77</accession>
    <name>B1KE77_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipid A biosynthesis lauroyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.241</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Kdo(2)-lipid IV(A) lauroyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lpxL</name>
        <name evidence="9" type="ordered locus">Swoo_0768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid IVA + dodecanoyl-[ACP] = dodecanoyl-(Kdo)2-lipid IVA + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:28442"/>
            <dbReference type="Rhea" id="RHEA-COMP:9644"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:60365"/>
            <dbReference type="ChEBI" id="CHEBI:61524"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:65264"/>
            <dbReference type="EC" id="2.3.1.241"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis; KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the LpxL/LpxM/LpxP family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.241" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0768"/>
    <dbReference type="EnsemblBacteria" id="ACA85063">
        <property type="protein sequence ID" value="ACA85063"/>
        <property type="gene ID" value="Swoo_0768"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0768"/>
    <dbReference type="eggNOG" id="COG1560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049421_1_1_6"/>
    <dbReference type="OMA" id="IEIMPPL"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00360">
        <property type="reaction ID" value="UER00485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008913">
        <property type="term" value="F:lauroyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01942">
        <property type="entry name" value="Lipid_A_LpxL_LpxP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011920">
        <property type="entry name" value="Lipid_A_LpxL_LpxP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02207">
        <property type="entry name" value="lipid_A_htrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="8">
        <location>
            <begin position="132"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="307" mass="35082" checksum="65AFCE4DFAF55C65" modified="2008-04-29" version="1">MVEKAQFSNHLFHPKFWLLWLGVGLMRLTQLLPLSAQMKIGAGLGRLAKKLLGSRVHTAKRNLELCFPDMPQAEQEVLLNKNFEETGKAIFDTINAWWWSDDKIQRHMTIKGQEHVEQTLKDGNGVILFAVHCLPLEMGARIFGQFQPGVGVYRPHNNPVMEYLQVKGRLRSNKALVPKRDIRQMVRCLRSPDVIWYTADQDFGRSSATFIPFFAMPDAATITGATTLARLGKAKVLPFSVERNTDDKGYTIEIMAPLDSFPTKDEVEDAKRGNGIIEQIINKNRAQYMWLHRRFKTRPNESDPSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE95</accession>
    <name>B1KE95_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 16">Phospholipase A1</fullName>
            <ecNumber evidence="6 16">3.1.1.32</ecNumber>
            <ecNumber evidence="7 16">3.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphatidylcholine 1-acylhydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Swoo_0786</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18689"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:57875"/>
            <dbReference type="EC" id="3.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="16">Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer; dimerization is reversible, and the dimeric form is the active one.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell outer membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="16">One of the very few enzymes located there.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the phospholipase A1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.32" evidence="6 16"/>
    <dbReference type="EC" id="3.1.1.4" evidence="7 16"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323428.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0786"/>
    <dbReference type="EnsemblBacteria" id="ACA85081">
        <property type="protein sequence ID" value="ACA85081"/>
        <property type="gene ID" value="Swoo_0786"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0786"/>
    <dbReference type="eggNOG" id="COG2829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045813_2_1_6"/>
    <dbReference type="OMA" id="WGGCRSV"/>
    <dbReference type="OrthoDB" id="1546598at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052740">
        <property type="term" value="F:1-acyl-2-lysophosphatidylserine acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052739">
        <property type="term" value="F:phosphatidylserine 1-acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00541">
        <property type="entry name" value="OMPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003187">
        <property type="entry name" value="PLipase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036541">
        <property type="entry name" value="PLipase_A1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40457">
        <property type="entry name" value="PTHR40457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02253">
        <property type="entry name" value="PLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01486">
        <property type="entry name" value="PHPHLIPASEA1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56931">
        <property type="entry name" value="SSF56931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0106">Calcium</keyword>
    <keyword evidence="15 16" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="13 16 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 16" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019616458" description="Phospholipase A1" evidence="16">
        <location>
            <begin position="29"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU366027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA85081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="331" mass="38060" checksum="E20D836E37B68648" modified="2008-04-29" version="1" precursor="true">MKSQSTIHLSLSLLALLPTFFISSSVYAHDLKNHETHHEEKTVATAKEDNTKTIEREHNNSLVDERVHDELATSELPFVMTPHNVNYILPATYNTSPNMAPFEEEAKEHPFDLDNMEAKFQISFKFPLMYNVFGDNGHLFVAYTNQSYWQVYNKDISSPFRETNHEPEIFMMFNNDWQVGPLRNSFWGVGAVHKSNGKSGSFSRSWNRIYGTMVFDSGPFALGAKVWWRIPEDEKETPTSPEGDDNPDITDYMGNFELTGIYGIDEHRFTMMIRNNFSNPNYGAIEATWSYPIIGQLRIYTQYFNGYGESLIDYNSHTQRIGIGVSINDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEJ2</accession>
    <name>B1KEJ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324912.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2291"/>
    <dbReference type="EnsemblBacteria" id="ACA86570">
        <property type="protein sequence ID" value="ACA86570"/>
        <property type="gene ID" value="Swoo_2291"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2291"/>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083563_0_0_6"/>
    <dbReference type="OMA" id="HAINFSF"/>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="68"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="285" mass="31808" checksum="DE807EBA944F79E1" modified="2008-04-29" version="1" precursor="true">MKLSVKTILALVMGLSFSAVTYVYVVNEANGESQIMNSASLPLFLSQCVEKSVSTPLDLEGRLNVAVWNLYKQQKSGWDSVLTELVSSNELVLLQEAKLSKNLAQFIINNSQQVLMAKAFKVFKTPIGVMNLANVQAESACAYHATEPWIRFAKSALVSQYLLSNGENLMVVNLHGINFDWRLKAYRSQFALLAEQISVHTGPVIMAGDFNTWRQGRLDVVGEFATKLGLQEASYETDNRNRVFGKALDHLYYRGLKLQKAHSNTTEASDHNPIQASFTLIEKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEJ5</accession>
    <name>B1KEJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2294</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324915.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2294"/>
    <dbReference type="EnsemblBacteria" id="ACA86573">
        <property type="protein sequence ID" value="ACA86573"/>
        <property type="gene ID" value="Swoo_2294"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2294"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_3_6"/>
    <dbReference type="OMA" id="YIQTHIG"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="126"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="126"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25790" checksum="A3027B71C09A4B4E" modified="2008-04-29" version="1">MSKVLLVDDDLVFRELLEQALAEEGYRVICAEDGVAALSILEIESPDIILLDIMMPKLDGFGLLAARKEQIPVIIISAIDCESDRIKGYELGADDFLSKPFSVKELLVRMAALQRRVDLVRSERICSIEQIKDEVEFDDLQYCVSIASKRVLLTQTEFKLFKYLFERKGEVITKQELQRSVLQKELGKFDRNLDMHISNTRRKLANTELPKTLINTVRGQGYSFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN9</accession>
    <name>B1KEN9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326385.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3795"/>
    <dbReference type="EnsemblBacteria" id="ACA88054">
        <property type="protein sequence ID" value="ACA88054"/>
        <property type="gene ID" value="Swoo_3795"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3795"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902823_0_0_6"/>
    <dbReference type="OMA" id="LWVDDHP"/>
    <dbReference type="OrthoDB" id="1590996at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="202"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="36537" checksum="CE90145E6674AA73" modified="2008-04-29" version="1">MYTHFEEFSINTETFELVIAKELVQLDERVFQLFKLLIEDYPAHCSKQRCLDRIWPNTVVSDMSLAKLVSDTRKLFKKAGCQAPIIETVHGRGYRLSKELGQQLSSVDTLVGSESQLLPSGFEQVGREPSAKIPAQEESLSFTEKTLAQKGNLIVGFLLLIFMAFTLNHYLIPSVLTSAQTPVLKNNPQEVVYSQSPDAIGRILWVDDHPDNNVEEREVFRQQNIGVYSTTSTDEALLLLSIYGYEMVISDVGRREEPLAGLKLLRVLRESGTEIPYIIYTLNDTPQLHEAVSKSGGQGVAVDAESLFNLVMPHFKTLESEIKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KET4</accession>
    <name>B1KET4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SSS sodium solute transporter superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3840</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326429.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3840"/>
    <dbReference type="EnsemblBacteria" id="ACA88099">
        <property type="protein sequence ID" value="ACA88099"/>
        <property type="gene ID" value="Swoo_3840"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3840"/>
    <dbReference type="eggNOG" id="COG4146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_9_3_6"/>
    <dbReference type="OMA" id="FGMVLRI"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="523" mass="57404" checksum="94E0F88EBBF166B3" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEV3</accession>
    <name>B1KEV3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PBPb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323451.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0809"/>
    <dbReference type="EnsemblBacteria" id="ACA85104">
        <property type="protein sequence ID" value="ACA85104"/>
        <property type="gene ID" value="Swoo_0809"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0809"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080965_2_0_6"/>
    <dbReference type="OMA" id="HTNNITQ"/>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764357" description="PBPb domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="93"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="237" mass="26908" checksum="965664BE8BE8847F" modified="2008-04-29" version="1" precursor="true">MKGRLILSILLILSTWDSLAKEYHFVSIENLIEQEVGRKVLPHFYKKLGHSITITPLPGKRASTTVSVGEKDGEIMRIFTYGMEHPNTLRIPTPYYSLQTMAFYKKSSGVVINRKEDLQHYKLVKVRGVKHTNNITQGMPFVHDVDSTVAMMDLLELGRVQVALTNTIDGLLAIKARGYTDIISLSEPLDELSLYHYVHQEHSQLVDEVDSVIKQMKLNGELEKIIKQAEKEVFSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF08</accession>
    <name>B1KF08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323506.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0865"/>
    <dbReference type="EnsemblBacteria" id="ACA85159">
        <property type="protein sequence ID" value="ACA85159"/>
        <property type="gene ID" value="Swoo_0865"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0865"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119435_0_0_6"/>
    <dbReference type="OMA" id="MITYEWS"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="147" mass="16937" checksum="43902123E858537C" modified="2008-04-29" version="1">MHIRKGQKSDLNALIQFNLAMAKETEDLALDESVLTQGVNTLLSNPEKGFYLVAEVDGEIAGSLMVTFEWSDWRAKDYYWIQSVYIRPQNRRQGIYAKLYHEVKQIAEQNGGAASFRLYVEQDNAKAQSTYSALGMEKSYYQMYEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF46</accession>
    <name>B1KF46_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2308</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324929.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2308"/>
    <dbReference type="EnsemblBacteria" id="ACA86587">
        <property type="protein sequence ID" value="ACA86587"/>
        <property type="gene ID" value="Swoo_2308"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2308"/>
    <dbReference type="eggNOG" id="COG1448">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032440_0_1_6"/>
    <dbReference type="OMA" id="PTWPIHE"/>
    <dbReference type="OrthoDB" id="417859at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="PTHR11879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="27"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="401" mass="43891" checksum="CBBD0E1F97DC75FD" modified="2008-04-29" version="1">MFDTLTAMPADPILGLMNKYREDPRANKVDLGVGVYKDELGHTPILTCVKKAEQYRIDTEETKVYIGPTGSADFNTLLSQLAFGNDNPALLANRVRTVSTPGGTGSLRVAADFIKRASSSTKSGEAVIWVSDPTWANHTGLFEAAGVTVKTYPYYDYDTKSLKFDEMKAALSNVGPDDVVLLHACCHNPSGMDLTKEQWDQIIDLTKEQGFTPLIDMAYQGFGDGVDEDAYGVRKMAATVNNMILCSSCSKNFGLYRERIGACSIIGKDTASVNIAFSVLLYVVRCIYSMPPAHGAAIVETILGSQELKQEWLDELTVMRDRINGNRAMLVNKLKEKGVTDNFDFIAQQKGMFSFLGVNPQQVAQLQQDYGIYMVDSSRISIAGIGTGNVDHLAESIAKIL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF47</accession>
    <name>AROA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="1">EPSP synthase</shortName>
            <shortName evidence="1">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroA</name>
        <name type="ordered locus">Swoo_2309</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EPSP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324930.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KF47"/>
    <dbReference type="SMR" id="B1KF47"/>
    <dbReference type="STRING" id="392500.Swoo_2309"/>
    <dbReference type="EnsemblBacteria" id="ACA86588">
        <property type="protein sequence ID" value="ACA86588"/>
        <property type="gene ID" value="Swoo_2309"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2309"/>
    <dbReference type="eggNOG" id="COG0128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024321_0_0_6"/>
    <dbReference type="OMA" id="CPDIIPV"/>
    <dbReference type="OrthoDB" id="533829at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000099752" description="3-phosphoshikimate 1-carboxyvinyltransferase">
        <location>
            <begin position="1"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="1">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <sequence length="426" mass="45925" checksum="327D9813C0ED555E" modified="2008-04-29" version="1">MKQLRLETINKVQGTVNIPGSKSISNRALLLATLAKGTTTLTNLLDSDDIRYMLASLKQLGVNYRLSEDKTVCELDGLGAPINSNVAQTLFLGNAGTAMRPLCAALTLGEGEFILTGEPRMEERPIGDLVDALRQLGAEVTYLKSEGFPPLTINATGLNAGDVEIAGDLSSQFLTALLMVSPLAKGDVNIKIKGELVSKPYIDITLALMAQFGVKVINHDYERFEIKSGQSYVSPGKVLVEGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGAEIEWGDDYIISRVAKLNAVDLDMNHIPDAAMTIATAALFATGTTHIRNIYNWRIKETDRLAAMATELRKVGAIVDEGHDYISVTPPTKPHTANIDTYNDHRMAMCFSMLAFADCGITINDPDCTSKTFPDYFEQFAALAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF92</accession>
    <name>B1KF92_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2354"/>
    <dbReference type="EnsemblBacteria" id="ACA86633">
        <property type="protein sequence ID" value="ACA86633"/>
        <property type="gene ID" value="Swoo_2354"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2354"/>
    <dbReference type="eggNOG" id="ENOG5033Y1V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1577435_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="17601" checksum="FC69A7EBFD185EA0" modified="2008-04-29" version="1">MSSQIVMASSYSVKDEDSFKSALINALGSENSLQSGIQKQLNEIAKNAEKSKLKDSVISIESSIKPQSGDSETAISLTVADDLSTLTVPQAVAMELEVTVVDTVSADNSETGVAMSVSTTKSYPLDSNATTGIAQVVTALGLFNEGKLFDAKLTSATTKESASKEKPAS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-11-25" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI8</accession>
    <name>KATG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Catalase-peroxidase</fullName>
            <shortName evidence="1">CP</shortName>
            <ecNumber evidence="1">1.11.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Peroxidase/catalase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">katG</name>
        <name type="ordered locus">Swoo_3905</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + H2O2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="1">Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer or homotetramer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326493.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KFI8"/>
    <dbReference type="SMR" id="B1KFI8"/>
    <dbReference type="STRING" id="392500.Swoo_3905"/>
    <dbReference type="EnsemblBacteria" id="ACA88163">
        <property type="protein sequence ID" value="ACA88163"/>
        <property type="gene ID" value="Swoo_3905"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3905"/>
    <dbReference type="eggNOG" id="COG0376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025424_2_0_6"/>
    <dbReference type="OMA" id="EEIFWGP"/>
    <dbReference type="OrthoDB" id="49441at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01961">
        <property type="entry name" value="Catal_peroxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="PTHR30555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="SSF48113"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00198">
        <property type="entry name" value="cat_per_HPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0376">Hydrogen peroxide</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0575">Peroxidase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5000316507" description="Catalase-peroxidase">
        <location>
            <begin position="22"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-250)" evidence="1">
        <location>
            <begin position="102"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-102)" evidence="1">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01961"/>
        </source>
    </evidence>
    <sequence length="736" mass="81474" checksum="1E411341E32F9B0A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM2</accession>
    <name>B1KFM2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SMP-30/Gluconolaconase/LRE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326527.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3940"/>
    <dbReference type="EnsemblBacteria" id="ACA88197">
        <property type="protein sequence ID" value="ACA88197"/>
        <property type="gene ID" value="Swoo_3940"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3940"/>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_0_1_6"/>
    <dbReference type="OMA" id="PTNLAFG"/>
    <dbReference type="OrthoDB" id="966287at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766551" evidence="1">
        <location>
            <begin position="24"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="SGL" evidence="2">
        <location>
            <begin position="42"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="295" mass="32441" checksum="23E383F9C88A02C6" modified="2008-04-29" version="1" precursor="true">MKGVSFLSCIALLLLSPMGTLLADQRHSEDWVKDQVFTSGVEGPAVNSKGELFAVNFAKEGTIGKVTAQHKASHFMTLPEGSVGNGIRFDKQDNMYIADYAGHNILRVDAGTEVAYVFSHQPKMNQPNDIAMMDSGILFASDPNWSNSSGQLWRIDTDGVTQLLESDMGTTNGVEVSPDNKRLYVNESVQRKVWVYDLNMQGEISNKRLLIEFADHGLDGMRTDIHGNLYIARYGAGVVAVVSASGELLEEIRLKGQHPTNVAFGGEDGHSLFITMQKRGAIEHVRVKYAGRTFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS7</accession>
    <name>B1KFS7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">bPH_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323590.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85243">
        <property type="protein sequence ID" value="ACA85243"/>
        <property type="gene ID" value="Swoo_0950"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0950"/>
    <dbReference type="eggNOG" id="ENOG503172B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137895_0_0_6"/>
    <dbReference type="OMA" id="SITHFAV"/>
    <dbReference type="OrthoDB" id="1682253at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012544">
        <property type="entry name" value="PHb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037063">
        <property type="entry name" value="PHb_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08000">
        <property type="entry name" value="bPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bPH_1" evidence="1">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="14044" checksum="DD6BEDAF3488154A" modified="2008-04-29" version="1">MGLLDSLMGNASEVNLEELTEELNPIMGDNEQLHLAYKVIRDMFVFTNKRLILIDKQGMTGKKVSYHSIPYKAITHFEVETAGRFDMDSELKLWISGQKEPLVKELKKGTDVVGIQKTIANFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG35</accession>
    <name>B1KG35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S24 and S26 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325084.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2465"/>
    <dbReference type="MEROPS" id="S24.003"/>
    <dbReference type="EnsemblBacteria" id="ACA86742">
        <property type="protein sequence ID" value="ACA86742"/>
        <property type="gene ID" value="Swoo_2465"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2465"/>
    <dbReference type="eggNOG" id="COG1974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_0_4_6"/>
    <dbReference type="OMA" id="IHEYDQF"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S24" evidence="1">
        <location>
            <begin position="7"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15501" checksum="D8C430BA386C0C49" modified="2008-04-29" version="1">MKLITISASAGITGFESPAADYKQLELSLDELLVEHPSATFLARANGSSMQGVGIFDGDILIVDRHVTVTNQDIIVANYNGSFVCKIIDTKRKLLLSANEEHQVVTIHEYDQFSVEGVVIRSIRCHRASPLFTGGGSNRCHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG79</accession>
    <name>B1KG79_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326546.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88216">
        <property type="protein sequence ID" value="ACA88216"/>
        <property type="gene ID" value="Swoo_3959"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3959"/>
    <dbReference type="eggNOG" id="ENOG50331HE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135628_0_1_6"/>
    <dbReference type="OMA" id="GFRTHRR"/>
    <dbReference type="OrthoDB" id="1899465at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015097">
        <property type="term" value="F:mercury ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004891">
        <property type="entry name" value="Mercury-R_MerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03203">
        <property type="entry name" value="MerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="130" mass="14207" checksum="54B2B77001745B61" modified="2008-04-29" version="1">MNKPAQILLDRLAITGSALCALHCIAGPMLLVLFPSLLALPVDDHFYHILMVWFVIPTSSIAVLLGCTRHKDPMVLVLAFFGIIGLGITAIYGHDLLGETGEKLATLAASFLLVFAHWRNYSLCRNDSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG94</accession>
    <name>B1KG94_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell division protein ZapA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Z ring-associated protein ZapA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3974</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Interacts with FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZapA family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326561.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3974"/>
    <dbReference type="EnsemblBacteria" id="ACA88231">
        <property type="protein sequence ID" value="ACA88231"/>
        <property type="gene ID" value="Swoo_3974"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3974"/>
    <dbReference type="eggNOG" id="COG3027">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116623_2_0_6"/>
    <dbReference type="OMA" id="NICYELH"/>
    <dbReference type="OrthoDB" id="1802106at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007838">
        <property type="entry name" value="Cell_div_ZapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036192">
        <property type="entry name" value="Cell_div_ZapA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042233">
        <property type="entry name" value="Cell_div_ZapA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34981">
        <property type="entry name" value="PTHR34981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05164">
        <property type="entry name" value="ZapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102829">
        <property type="entry name" value="SSF102829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0717">Septation</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="102" mass="11502" checksum="26A9868FDDA0B157" modified="2008-04-29" version="1">MSSHAIEISLLGRTYSIACPPGQETALQHVAQKLEKQLTSLKARTNNLSREEIAIMAALNIGYELLEEQQKNQDYNRQMDEKIGLLQSTLEDALVERSTKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGG4</accession>
    <name>B1KGG4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione hydrolase proenzyme</fullName>
            <ecNumber evidence="4">2.3.2.2</ecNumber>
            <ecNumber evidence="4">3.4.19.13</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase large chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase small chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0999</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Cleaved by autocatalysis into a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="4"/>
    <dbReference type="EC" id="3.4.19.13" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0999"/>
    <dbReference type="MEROPS" id="T03.025"/>
    <dbReference type="EnsemblBacteria" id="ACA85292">
        <property type="protein sequence ID" value="ACA85292"/>
        <property type="gene ID" value="Swoo_0999"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0999"/>
    <dbReference type="eggNOG" id="COG0405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014813_3_2_6"/>
    <dbReference type="OMA" id="MFCLFYD"/>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764853" description="Glutathione hydrolase proenzyme" evidence="5">
        <location>
            <begin position="20"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="564" mass="61095" checksum="2B8D61CE13344ECB" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM4</accession>
    <name>B1KGM4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="13" type="ordered locus">Swoo_1059</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323698.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1059"/>
    <dbReference type="EnsemblBacteria" id="ACA85352">
        <property type="protein sequence ID" value="ACA85352"/>
        <property type="gene ID" value="Swoo_1059"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1059"/>
    <dbReference type="eggNOG" id="COG0525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_0_2_6"/>
    <dbReference type="OMA" id="FATKLWN"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="14"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="687"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="897"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="937"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="554"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA85352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="966" mass="109764" checksum="346CC9D4BDF7BA48" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGR0</accession>
    <name>B1KGR0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2502"/>
    <dbReference type="EnsemblBacteria" id="ACA86779">
        <property type="protein sequence ID" value="ACA86779"/>
        <property type="gene ID" value="Swoo_2502"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2502"/>
    <dbReference type="eggNOG" id="ENOG5031AJH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2345105_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="97" mass="10830" checksum="17A8F12A40503451" modified="2008-04-29" version="1">MELFLKIACGIATLFGCITWFGLMLASLPGAEVSKSIYARTIRGLFYTHPVLVIIILCLIRYYVDSIPLALLLTILPLLPLAGVYLIFTLWERNGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGS9</accession>
    <name>B1KGS9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DotU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325139.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2521"/>
    <dbReference type="EnsemblBacteria" id="ACA86798">
        <property type="protein sequence ID" value="ACA86798"/>
        <property type="gene ID" value="Swoo_2521"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2521"/>
    <dbReference type="eggNOG" id="COG3455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071818_0_1_6"/>
    <dbReference type="OMA" id="CAPLLTI"/>
    <dbReference type="OrthoDB" id="1650600at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017732">
        <property type="entry name" value="T4/T6SS_DotU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038522">
        <property type="entry name" value="T4/T6SS_DotU_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09850">
        <property type="entry name" value="DotU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03349">
        <property type="entry name" value="IV_VI_DotU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="DotU" evidence="2">
        <location>
            <begin position="42"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="261" mass="30260" checksum="C95D7CB81B7B8E5C" modified="2008-04-29" version="1">MKPQKQPLTEQQLDDVLFDEVRNIDADKEYWFQLRGDNINQLIDAATPLMGMVFRVRKLAVLDDVQKLYHNTVDDIMAIEAELTESGFGRAIILAYRYVLCSFIDEAVMNTPWGADSVWAEHSLLTRFHNETWGGEKVFSILQRLETEPASYRELLEFIYLCLCLGFEGRYKVVVNGREEFDKIVNRLYETLRHLRDEEPELLSNATDHVVNTKFQIGRQMPIWTIFAGFFVMLAVIFIFYSVSLANKSAGVLDQLFQILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGV9</accession>
    <name>B1KGV9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queE</name>
        <name evidence="7" type="ordered locus">Swoo_2551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325169.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2551"/>
    <dbReference type="EnsemblBacteria" id="ACA86828">
        <property type="protein sequence ID" value="ACA86828"/>
        <property type="gene ID" value="Swoo_2551"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2551"/>
    <dbReference type="eggNOG" id="COG0602">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066739_3_0_6"/>
    <dbReference type="OMA" id="CDVKESW"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027609">
        <property type="entry name" value="rSAM_QueE_Proteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04322">
        <property type="entry name" value="rSAM_QueE_Ecoli"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="18"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="37"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="136"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="24868" checksum="4F1E7E1AE70474AE" modified="2008-04-29" version="1">MKYPVNEVFETIQGEGFYTGVPAIFVRLQGCPVGCSWCDTKHTWELLDVNKVQPEMVIQVDGTIGRWSELTTSELISFLKQKEFTASHVVITGGEPCLHDLTAMTEEFNDAGYSTQIETSGTFEVHCSEKTWVTVSPKLKMKAGLAVLPQALKRANEIKHPVATASHIDDLDELLNGVDLKGKTICLQPISQKTRATELAMRVCIERNWRLSIQTHKYLDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGW1</accession>
    <name>B1KGW1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2553</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325171.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2553"/>
    <dbReference type="EnsemblBacteria" id="ACA86830">
        <property type="protein sequence ID" value="ACA86830"/>
        <property type="gene ID" value="Swoo_2553"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2553"/>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108530_1_0_6"/>
    <dbReference type="OMA" id="NHWHLLM"/>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023826">
        <property type="entry name" value="Rhom-like_SP_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03902">
        <property type="entry name" value="rhom_GG_sort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="42"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="202" mass="22647" checksum="42A931B8900651F4" modified="2008-04-29" version="1" precursor="true">MSKLTSLFGKSFPVLVLFTLCAIGFYYAGFDNELAYRRSEITAGEYWRLFSGNLLHTNGWHLMMNLAGLWVIILLHQQYYRSLGFALIFILLCWLQGIGLYLFYPGLLGYVGLSGMLHGLFAYGALKDISVGMRSGYLLLIGVIVKVAYEQWFGASEQVTEMIGARVATEAHLIGVVTGILLFAVVAIYQKYFTNKPKEKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGZ4</accession>
    <name>B1KGZ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4050"/>
    <dbReference type="EnsemblBacteria" id="ACA88306">
        <property type="protein sequence ID" value="ACA88306"/>
        <property type="gene ID" value="Swoo_4050"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4050"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_8_3_6"/>
    <dbReference type="OMA" id="YKIATYG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="122" mass="14198" checksum="30454D2263A07F88" modified="2008-04-29" version="1">MANVMNMKKFSERAGLSAHTLRYYEKIGLLNNVQRNISGHRDYTSRDLDWINFVIRLKDTGMPLSNILEYAKLRALGSDTVKERQKLLEQHRECLKSHIELQQNHLAALEDKIGLYELNKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGZ8</accession>
    <name>B1KGZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4054"/>
    <dbReference type="EnsemblBacteria" id="ACA88310">
        <property type="protein sequence ID" value="ACA88310"/>
        <property type="gene ID" value="Swoo_4054"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4054"/>
    <dbReference type="eggNOG" id="ENOG5031G5B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1721106_0_0_6"/>
    <dbReference type="OMA" id="TTLMEQK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="88"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="152" mass="16445" checksum="F02E0219918C52BF" modified="2008-04-29" version="1">MTAIGGVVNINGFSTSLKPETRSVSEGYITPKLDRGSLDKTSAQVSTADTASISQAGKTAEKLDVGSAMVQLKDRGAEAAEKSEAESSSIIDKQIERIKERIEQLKQDLKGLQGDKSEVAQKKREMINAEILQLSGMLIKLYEEKAKQEGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH53</accession>
    <name>B1KH53_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chaperone NapD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">NapA signal peptide-binding chaperone NapD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">napD</name>
        <name evidence="5" type="ordered locus">Swoo_4109</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with the cytoplasmic NapA precursor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NapD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326694.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4109"/>
    <dbReference type="EnsemblBacteria" id="ACA88365">
        <property type="protein sequence ID" value="ACA88365"/>
        <property type="gene ID" value="Swoo_4109"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4109"/>
    <dbReference type="eggNOG" id="COG3062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155794_5_3_6"/>
    <dbReference type="OMA" id="YQHNEDA"/>
    <dbReference type="OrthoDB" id="1976760at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005048">
        <property type="term" value="F:signal sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051224">
        <property type="term" value="P:negative regulation of protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02200">
        <property type="entry name" value="NapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005623">
        <property type="entry name" value="Chaperone_NapD_NO3_reduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38603">
        <property type="entry name" value="PTHR38603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03927">
        <property type="entry name" value="NapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="83" mass="9037" checksum="621C5AE6CBE52CBE" modified="2008-04-29" version="1">MSQEYHVTSLVVHAAPAEVSQVEAKIRSLDGADIHAVTYEGKFVITLEGKTQKSILDNVEAINAFEGVLNSSLVYHQVEPIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH93</accession>
    <name>B1KH93_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323747.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1108"/>
    <dbReference type="EnsemblBacteria" id="ACA85401">
        <property type="protein sequence ID" value="ACA85401"/>
        <property type="gene ID" value="Swoo_1108"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1108"/>
    <dbReference type="HOGENOM" id="CLU_2737814_0_0_6"/>
    <dbReference type="OMA" id="CATNIDF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766604" evidence="1">
        <location>
            <begin position="20"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="71" mass="8064" checksum="767DC750C6E2D73F" modified="2008-04-29" version="1" precursor="true">MNLKNVLLLTTLLGISACATSVYDTVDINVEQEPQQDVLDSKADPMIEHNERLIKEGREDEWRKDVKGLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL7</accession>
    <name>B1KHL7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325242.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2625"/>
    <dbReference type="EnsemblBacteria" id="ACA86902">
        <property type="protein sequence ID" value="ACA86902"/>
        <property type="gene ID" value="Swoo_2625"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2625"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012397_0_0_6"/>
    <dbReference type="OMA" id="VTEDMAH"/>
    <dbReference type="OrthoDB" id="670657at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021878">
        <property type="entry name" value="TgpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11992">
        <property type="entry name" value="TgpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="405"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="667" mass="76044" checksum="F286BFAA0B833499" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY6</accession>
    <name>B1KHY6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S46 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326793.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4208"/>
    <dbReference type="MEROPS" id="S46.003"/>
    <dbReference type="EnsemblBacteria" id="ACA88464">
        <property type="protein sequence ID" value="ACA88464"/>
        <property type="gene ID" value="Swoo_4208"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4208"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4990">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013776_0_0_6"/>
    <dbReference type="OMA" id="KDWFFNP"/>
    <dbReference type="OrthoDB" id="99817at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070009">
        <property type="term" value="F:serine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044248">
        <property type="term" value="P:cellular catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901565">
        <property type="term" value="P:organonitrogen compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019500">
        <property type="entry name" value="Pep_S46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000126">
        <property type="entry name" value="V8_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38469">
        <property type="entry name" value="PTHR38469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10459">
        <property type="entry name" value="Peptidase_S46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00673">
        <property type="entry name" value="V8_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767364" evidence="2">
        <location>
            <begin position="19"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="739" mass="82874" checksum="27A778E50E18A1B9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI29</accession>
    <name>B1KI29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1214</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323853.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1214"/>
    <dbReference type="EnsemblBacteria" id="ACA85507">
        <property type="protein sequence ID" value="ACA85507"/>
        <property type="gene ID" value="Swoo_1214"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1214"/>
    <dbReference type="eggNOG" id="COG2860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064906_2_1_6"/>
    <dbReference type="OMA" id="RAPRAWN"/>
    <dbReference type="OrthoDB" id="1665397at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="7"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="94"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="211" mass="22602" checksum="EB844974E4F603AA" modified="2008-04-29" version="1" precursor="true">MTSWFYFFDLCGTAVFALSGALAAGRHRMDPFGVIVLASVTAVGGGSIRDALLGTTPVFWIRDPNYIIVILLTVLLTMLIVRKPKRVPQHTLPVADALGLALFTVIGAEKALSLELGGMIAVVMGLITGVGGGMIRDLLCRQVPMILRTEIYATASILGGISYSLSLHLGAQDKQALIFAMVVALGIRLAAIKWHLSLPAFDLKTNKQNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIB3</accession>
    <name>B1KIB3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2688</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325304.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2688"/>
    <dbReference type="EnsemblBacteria" id="ACA86964">
        <property type="protein sequence ID" value="ACA86964"/>
        <property type="gene ID" value="Swoo_2688"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2688"/>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002338_0_1_6"/>
    <dbReference type="OMA" id="NTAKQWP"/>
    <dbReference type="OrthoDB" id="754526at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1290" mass="140731" checksum="5D84C2E353FA7D77" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIH7</accession>
    <name>B1KIH7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribonuclease R</fullName>
            <shortName evidence="7">RNase R</shortName>
            <ecNumber evidence="7">3.1.13.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rnr</name>
        <name evidence="10" type="ordered locus">Swoo_4217</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RNR ribonuclease family. RNase R subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326801.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4217"/>
    <dbReference type="EnsemblBacteria" id="ACA88473">
        <property type="protein sequence ID" value="ACA88473"/>
        <property type="gene ID" value="Swoo_4217"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4217"/>
    <dbReference type="eggNOG" id="COG0557">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002333_7_0_6"/>
    <dbReference type="OMA" id="DWYEYRS"/>
    <dbReference type="OrthoDB" id="1602988at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01895">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004476">
        <property type="entry name" value="RNase_II/RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011805">
        <property type="entry name" value="RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013668">
        <property type="entry name" value="RNase_R_HTH_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08461">
        <property type="entry name" value="HTH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00358">
        <property type="entry name" value="3_prime_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02063">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="9">
        <location>
            <begin position="644"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="724"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="724"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="799"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="826" mass="93144" checksum="2725178C21867C56" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIR0</accession>
    <name>B1KIR0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326883.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4302"/>
    <dbReference type="EnsemblBacteria" id="ACA88556">
        <property type="protein sequence ID" value="ACA88556"/>
        <property type="gene ID" value="Swoo_4302"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4302"/>
    <dbReference type="eggNOG" id="ENOG5032SMP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1795174_0_0_6"/>
    <dbReference type="OMA" id="NFLWINA"/>
    <dbReference type="OrthoDB" id="1945935at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="144" mass="16702" checksum="363A9F47C341F69E" modified="2008-04-29" version="1">MNKELLVKDFIIITVIVSLWVNASEVFRYFLFVRPEMHSYLSVVPNVADMNWGIFTIWGLWDTLLTALYVFLFWLCAQVFGNNTKSIVISGVMSWCFFFVLFWVGMANMNLSSWSYLVIVLPMALVETLVASYIASRLYLRKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ03</accession>
    <name>B1KJ03_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-containing alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323997.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1359"/>
    <dbReference type="EnsemblBacteria" id="ACA85651">
        <property type="protein sequence ID" value="ACA85651"/>
        <property type="gene ID" value="Swoo_1359"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1359"/>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007207_0_0_6"/>
    <dbReference type="OMA" id="HAMSHQV"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="9"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="39715" checksum="FE5C952FE074BBBF" modified="2008-04-29" version="1">MAAKFFIPSVNVLGQNAVDEAIGDIKTLGFKHALIVTDKPLVEIGLVGQVAEKLGAAGILSTVFDGVQPNPTVGNVEAGLALLNANECDFVVSLGGGSPHDCAKGIALVATNGGSIKDYEGLDVSTKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKHTTPILSVNDPELMLAKPAGLTAATGMDALTHAVEAYVSIAANPITDACAIKAIELIKGNLVEAVDNGQNIDARDQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAQVSAARLKDVAKAMGVEVASMSDEQGAAAAIEAIKSLSVAVKIPENLTKLGVKAEDIPTLAENALKDACGLTNPKQASHEEICQIFTNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ04</accession>
    <name>B1KJ04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Porin, gram-negative type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323998.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85652">
        <property type="protein sequence ID" value="ACA85652"/>
        <property type="gene ID" value="Swoo_1360"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1360"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062223_0_0_6"/>
    <dbReference type="OMA" id="GEDEVWA"/>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="81"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="383" mass="43466" checksum="B996CB0E54FC5848" modified="2008-04-29" version="1" precursor="true">MQISPIAQFITLTLLATSFDLAAEQKVTLASLKLQIEALQKQVMLLEQAQKQEAQKREKAISQADKPPEQVQPKSETGNNTLKVYATMRPTYGYFDEGGETFYDVRDALSHIGLKATNEFMPGWRAELHGEWGVDLSNNGDFGKARRAYVALGGPYGRIGIGKQRPPQYLLIAEYVDIFNHANSPFAYDPESVFFVNNMLTYRLSVENFSWLAAAQFDGGSGSNSADLVNLGLSYDNDGFHGAVTYLEQSSIDGNLTTGEDEVWAVSLAKEFGNGFYLAGAYQDKNYQRDGISQDRNGHTLDIASAYRISQQFRVKLGYFDFDDGRETFLSQRYHGFNTTLEWLPDDNLRFHLEYLTKDYDYLNDFDSWTVGFRYDFAKDWRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ36</accession>
    <name>B1KJ36_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2780</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2780"/>
    <dbReference type="EnsemblBacteria" id="ACA87056">
        <property type="protein sequence ID" value="ACA87056"/>
        <property type="gene ID" value="Swoo_2780"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2780"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_3_6"/>
    <dbReference type="OMA" id="AWRHPEV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="61"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="162"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="216" mass="24789" checksum="BA6D75A1022D0308" modified="2008-04-29" version="1">MLENEYTNMQKVEGIRHIVEVNNIISKQTQEQVPTELSAWIVLVATKRDKRAFTAIFTFFAPKIKRFGIKQLNTDAMAAELVQETLSRVWNKASLFDPNKGAATTWVYSIMRNAAFDMLRKIKVKNELLLGDDIWPIEAEEYSTSEEFSDHLMDRQIADYVDQLPEAQKLVVKGVYFQELSQEQLAKQLNIPIGTVKSRLRLALAKLKEQVGESHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ71</accession>
    <name>B1KJ71_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2816"/>
    <dbReference type="EnsemblBacteria" id="ACA87091">
        <property type="protein sequence ID" value="ACA87091"/>
        <property type="gene ID" value="Swoo_2816"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2816"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_1_0_6"/>
    <dbReference type="OMA" id="GWADTEL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="3">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="441" mass="49187" checksum="4C6A0D885D6175A0" modified="2008-04-29" version="1">MISTMYQNRRTRLFNALPNKSFVIISGYQQKVRSKNIKYHFRQDNDFLYLTGFNEPDAVALLYCDESKDTGYSYTLLCRPKDEAQEVSFGARAGVLGALSQYGADDAFDIAELEQVLLSKLTDHANLFISDELGRFSSQVIGWLNHQRLNCSFDTIKQHRTLTPLAKVLHPMRVIKSSHEIDKIKAAVHASTAGHIAVMRACKPGVNEGLLSASFNFAISQYGCSEVAYPNIVASGNNACCLHYEENCCNLADGQMLLIDAGGELEHYASDITRTYPVNGKFNEAQRDIYQLVLNALDAAIDKVKPGANWNSLYETCMEVMAKGLLELGLLSGNIDDIMKDESYKRFTVHKTGHWLGMDVHDVGPYHDENGQWRKLESGMVFTIEPGIYIPLSATDIPEKYRGMGIRIEDDILVTQNGFENLSAGVPRTIGEIESIMSPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ96</accession>
    <name>B1KJ96_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326895.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4315"/>
    <dbReference type="EnsemblBacteria" id="ACA88568">
        <property type="protein sequence ID" value="ACA88568"/>
        <property type="gene ID" value="Swoo_4315"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4315"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="WGGEYET"/>
    <dbReference type="OrthoDB" id="38744at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="865"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="891"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="966"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="993"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1028" mass="113327" checksum="2D0919E653FD79F2" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJA4</accession>
    <name>B1KJA4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PhoH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4323</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326902.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4323"/>
    <dbReference type="EnsemblBacteria" id="ACA88576">
        <property type="protein sequence ID" value="ACA88576"/>
        <property type="gene ID" value="Swoo_4323"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4323"/>
    <dbReference type="eggNOG" id="COG1875">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022283_0_0_6"/>
    <dbReference type="OMA" id="KMSPWAQ"/>
    <dbReference type="OrthoDB" id="445854at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="5">
        <location>
            <begin position="7"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="272"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="464" mass="52133" checksum="F6F27C817945BE29" modified="2008-04-29" version="1">MEQDDRKLFVLDTNVLLHEPLAIYSFKEHDVVVPMTVLEELDQIKDRKRDVSRDARVAIRALEDILGGTTTPEEIVQGVKLPRREDHGDASGSLAIFPDHQLEMTQASLPGDNNDNRIINTALHLQKIHEPRTVVLVTKDINMRLKAKGAGILLVEDYRTDQLIDDIRFLTKGFHQFDGDFWERKEHVTTETQGRHTVHTVPVAEVGDENFYINQYLMDKDSNFCGRVIEKNDTDLHLLDLGKDRLLNLDAWGIRPKNIYQGMAMQALLDPDIDLVILTGPAGCGKTLLAIAAALEMVVERGLYDKVIVTRNTPEIAESIGFLPGTEEEKMAPWLAAITDTLEVLHKNDVNPSGSMNYIMDKANIQFKSINFMRGRSIQNSVVILDECQNLTASQIKTMITRMGEGTKLICSGNLAQIDTNYLTAVTSGLTYIVERFKNFEGSANIYLNGVVRSRLAEFAEENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD1</accession>
    <name>B1KJD1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4240 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326929.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4350"/>
    <dbReference type="EnsemblBacteria" id="ACA88603">
        <property type="protein sequence ID" value="ACA88603"/>
        <property type="gene ID" value="Swoo_4350"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4350"/>
    <dbReference type="eggNOG" id="COG3831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085061_2_2_6"/>
    <dbReference type="OMA" id="MDETEFW"/>
    <dbReference type="OrthoDB" id="2016600at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025334">
        <property type="entry name" value="DUF4240"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14024">
        <property type="entry name" value="DUF4240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="19599" checksum="39BD513FE5F2541D" modified="2008-04-29" version="1">MTEAEFWQLVTRSSPEQDQSSLADNLKAKLEPLTDGELVEFDKFFGQQMRRSYFWSMWGAAYIITGCDSEYAFAEFRCFLISLGKEWYDKVIESPDLLGTLDQWPEKDGYAYPFLDEYDLIAGQIFEDRTGEELPFVPSGMATPQGKKFSTKKKLLKSNYPQLSERFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJD3</accession>
    <name>B1KJD3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326931.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4352"/>
    <dbReference type="EnsemblBacteria" id="ACA88605">
        <property type="protein sequence ID" value="ACA88605"/>
        <property type="gene ID" value="Swoo_4352"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4352"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1041351_0_0_6"/>
    <dbReference type="OMA" id="LYVEDSC"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="146"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="265" mass="29598" checksum="1F9F6E146D45F45B" modified="2008-04-29" version="1">MSTLLPSELSILLLEASDTQRKIISSKLSEEGFSNIQTATTITDALTIISRYQPDLITSAMHFEDGTALDLLKQVRENSQYEDIQFMLVSSECRREHLEVYRQAGVVAILPKPFASEHLLKALNSTLDLLSDDELELSHFDVHDLKVLVVDDSKMARNIIKRTISNLGLRLITEAVDGAQAIEIMQDNLFDLVITDYNMPSVDGLALTQFIRNDSQQCHVPILMVSSEANDAHLTNVAQAGVNALCDKPFEPKLVKQLLYQLLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJP2</accession>
    <name>B1KJP2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polyketide-type polyunsaturated fatty acid synthase PfaA</fullName>
            <ecNumber evidence="8">2.3.1.94</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1423</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.94" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1423"/>
    <dbReference type="EnsemblBacteria" id="ACA85715">
        <property type="protein sequence ID" value="ACA85715"/>
        <property type="gene ID" value="Swoo_1423"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1423"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_30_2_6"/>
    <dbReference type="OMA" id="GEIVAYM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047879">
        <property type="term" value="F:erythronolide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004432">
        <property type="entry name" value="Omega_3_polyunsat_FA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02813">
        <property type="entry name" value="omega_3_PfaA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1265"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1378"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1484"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1588"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1696"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1805"/>
            <end position="1885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1459"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1307"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1416"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1522"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1626"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1734"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="2750" mass="291700" checksum="D6705D176281BA21" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK17</accession>
    <name>B1KK17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate dehydrogenase (Acetyl-transferring)</fullName>
            <ecNumber evidence="4">1.2.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2931</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325540.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2931"/>
    <dbReference type="EnsemblBacteria" id="ACA87204">
        <property type="protein sequence ID" value="ACA87204"/>
        <property type="gene ID" value="Swoo_2931"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2931"/>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_5_0_6"/>
    <dbReference type="OMA" id="FGMPGVT"/>
    <dbReference type="OrthoDB" id="1248201at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="3">
        <location>
            <begin position="44"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="329" mass="35998" checksum="ACC8377C35909A15" modified="2008-04-29" version="1">MLPTNEQRRWMYRNMLISRYMEERIETIYMEGKKPIFNMANGPIPGEMHLSNGQEPCAVGVCCHLGTEDIVTATHRPHHIAIAKGVDLKKMMAEIFGKKTGLSGGRGGHMHLFDKDVNFACSGIIAQGMGPAVGAALSRKLQRKSGIAIAYIGEGAANQGAFHETLNLASVWKLPVIFIIEDNDWGISVAKSTSTSVSKNSDRAAAYGMPGIFIKDNCPDQIFSATAAAVEQARCGDGPTLIEIKTSRLAGHFMGDAEDYRPKGEKENLLKNDPIPTYRQALLDEDVITIEEDSALVQETQQLIEDAITFARESDEPAPEEALEHVFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK21</accession>
    <name>B1KK21_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325544.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2935"/>
    <dbReference type="EnsemblBacteria" id="ACA87208">
        <property type="protein sequence ID" value="ACA87208"/>
        <property type="gene ID" value="Swoo_2935"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2935"/>
    <dbReference type="eggNOG" id="COG0095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084176_0_0_6"/>
    <dbReference type="OrthoDB" id="871298at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="19"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="25762" checksum="0AF536EBAE64498A" modified="2008-04-29" version="1">MDPVTALSWEKNALERIKVDGQYRLLVWEPETSVMVLPTGPRWKMPPESTKQMNKFGWQVQYRQTGGSPVPQTSGVINLSMVYPWPKDNPLSMSGSYQLLIDILTQWLGHYCIQGETGEVEGAYCNGAYNFVVKEQKLIGTAQRISSNTNQQYFVLAHAFILFDAGIPQLIKAVNHCYQSLNLTEVFDTSAMTSLTLLDPQLKGKKAALIENLESTTHAILKAHSQQQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK61</accession>
    <name>B1KK61_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327018.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4440"/>
    <dbReference type="EnsemblBacteria" id="ACA88692">
        <property type="protein sequence ID" value="ACA88692"/>
        <property type="gene ID" value="Swoo_4440"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4440"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_6_6"/>
    <dbReference type="OMA" id="FIDYLAH"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="197" mass="22648" checksum="694A8325782E6EF8" modified="2008-04-29" version="1">MRHIEKTMVASFPRIETPRLILNETTLADTGSVFSLFSDPQVLIYYDIEQFNEPEQAMELINSDAKKYKDGQMLRWAVREKLSSKYIGGCGINRFELSRHTAVIGYEFIQDSWGKGFATESIQAVVDFCFSNHSPHFVNRIEAYVMQGNLASEAILTKLGFDKEGILKQHSYWKGQYHDLALFSKLKCNHHNKQTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH6</accession>
    <name>B1KKH6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Malate synthase</fullName>
            <ecNumber evidence="1">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.3.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324162.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1528"/>
    <dbReference type="EnsemblBacteria" id="ACA85816">
        <property type="protein sequence ID" value="ACA85816"/>
        <property type="gene ID" value="Swoo_1528"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1528"/>
    <dbReference type="eggNOG" id="COG2225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018928_0_0_6"/>
    <dbReference type="OMA" id="CHKRGAP"/>
    <dbReference type="OrthoDB" id="322024at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="PTHR42902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="Malate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="SSF51645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="468" mass="52054" checksum="67A10487F667F3FD" modified="2008-04-29" version="1">MAQEVIHNAQQGAMDVAQLGLDANCDVAAHLQAGYISAPVETNKTQERLKVNGEVVDGQDKVLNEGALSLLSSLCRQFAAEVSELLENRKSQQAKYDAGGTLDFLPQTKAVREGNWQVRGIPADLINRRVEIAGSVDPLMLINGLNSNANVFVADLEESPASSWNELIEKQVNLRGAVRGEIEFTSPETGKYYLLNDAPAVLFCRVRGLHMVEHHLEFDEAAIPAALFDFALYFYNNYRQLLAKGSGPYFYLPKMESHLEAKWWAKVFAFVEERFCLQPGTIKCTCLIETLPAVFEMDEILFELRSNIVALNCGRWDSDFSYINTGRNHSDELSTDKQMFTVGESFLSVYSRLLVKTCHKRGALAIGGVATYFQAKTNEISAERLEKIRIDKELEARNGHDGTCVEHLELVDAVTEIFNQYIGAEQANQLHITRDVDGPISARELLQGVGITTNVRLDIRADSESNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKJ9</accession>
    <name>B1KKJ9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325552.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2943"/>
    <dbReference type="EnsemblBacteria" id="ACA87216">
        <property type="protein sequence ID" value="ACA87216"/>
        <property type="gene ID" value="Swoo_2943"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2943"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_1_1_6"/>
    <dbReference type="OMA" id="QFLAAHT"/>
    <dbReference type="OrthoDB" id="1308229at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="8"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="378"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="672" mass="72733" checksum="D1EFA567D25D0733" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKM3</accession>
    <name>B1KKM3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2969"/>
    <dbReference type="EnsemblBacteria" id="ACA87240">
        <property type="protein sequence ID" value="ACA87240"/>
        <property type="gene ID" value="Swoo_2969"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2969"/>
    <dbReference type="HOGENOM" id="CLU_1730149_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="151" mass="16916" checksum="AA2A6ECE8A22613C" modified="2008-04-29" version="1" precursor="true">MIASALLSIKNFMAERIKSISFHLLFIFAVIIAVFSMSFINAGTNAHDGYTFGKYSGIILMVTVSPLAFLMFYIASLVGCKSSILTMRSAYLIISLSVFTISITRMMYYLVFSSYVHQNFGVPPAPWQNLVAISISLLFYILFYRSKIIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKQ1</accession>
    <name>B1KKQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325604.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2997"/>
    <dbReference type="EnsemblBacteria" id="ACA87268">
        <property type="protein sequence ID" value="ACA87268"/>
        <property type="gene ID" value="Swoo_2997"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2997"/>
    <dbReference type="eggNOG" id="COG2771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072786_0_0_6"/>
    <dbReference type="OMA" id="MICSITE"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005143">
        <property type="entry name" value="TF_LuxR_autoind-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036693">
        <property type="entry name" value="TF_LuxR_autoind-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03472">
        <property type="entry name" value="Autoind_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75516">
        <property type="entry name" value="SSF75516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="183"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="250" mass="28159" checksum="AF8E569A331720CA" modified="2008-04-29" version="1">MRLQEDSEHFLNIKQVSDVYHMFSSSSSSDEMMLCVKALQNLLEVDGVALINLILRPDHTITIERVVSSGFGFESKSVEWDNIYQKKKFQYIDPVVSCSASFRRSFNWASVPSMITLSEVQFNFLERAQEMGLKEGASIGSFSTRQIYKELTITSVCGCSLNPEQLASLELINAVSAQAMKRLILPAEKLTGRESEILAWSSEGKSSWEIGMICSITERTVKFHLKNIYKKLNVQNRAQAIVCAIRLGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY3</accession>
    <name>B1KKY3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidoglycan D,D-transpeptidase FtsI</fullName>
            <ecNumber evidence="7">3.4.16.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Penicillin-binding protein 3</fullName>
            <shortName evidence="7">PBP-3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ftsI</name>
        <name evidence="10" type="ordered locus">Swoo_4539</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transpeptidase family. FtsI subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327115.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4539"/>
    <dbReference type="EnsemblBacteria" id="ACA88789">
        <property type="protein sequence ID" value="ACA88789"/>
        <property type="gene ID" value="Swoo_4539"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4539"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009289_6_2_6"/>
    <dbReference type="OMA" id="HGKEEYY"/>
    <dbReference type="OrthoDB" id="213680at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02080">
        <property type="entry name" value="FtsI_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037532">
        <property type="entry name" value="FtsI_transpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0717">Septation</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PBP_dimer" evidence="9">
        <location>
            <begin position="62"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="8">
        <location>
            <begin position="256"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="578" mass="63964" checksum="9FDD3487BD43CFC9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL38</accession>
    <name>FPG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Formamidopyrimidine-DNA glycosylase</fullName>
            <shortName evidence="2">Fapy-DNA glycosylase</shortName>
            <ecNumber evidence="2">3.2.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase MutM</fullName>
            <shortName evidence="2">AP lyase MutM</shortName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mutM</name>
        <name evidence="2" type="synonym">fpg</name>
        <name type="ordered locus">Swoo_0078</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="2"/>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322728.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KL38"/>
    <dbReference type="SMR" id="B1KL38"/>
    <dbReference type="STRING" id="392500.Swoo_0078"/>
    <dbReference type="EnsemblBacteria" id="ACA84379">
        <property type="protein sequence ID" value="ACA84379"/>
        <property type="gene ID" value="Swoo_0078"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0078"/>
    <dbReference type="eggNOG" id="COG0266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038423_1_1_6"/>
    <dbReference type="OMA" id="GVHLRMT"/>
    <dbReference type="OrthoDB" id="1162346at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00103">
        <property type="entry name" value="Fapy_DNA_glycosyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015887">
        <property type="entry name" value="DNA_glyclase_Znf_dom_DNA_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01242">
        <property type="entry name" value="ZF_FPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0326">Glycosidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="initiator methionine" description="Removed" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_1000094078" description="Formamidopyrimidine-DNA glycosylase">
        <location>
            <begin position="2"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="FPG-type" evidence="2">
        <location>
            <begin position="236"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA" evidence="2">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for beta-elimination activity" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for delta-elimination activity" evidence="2">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00103"/>
        </source>
    </evidence>
    <sequence length="271" mass="29881" checksum="DC1056B16EF94AFD" modified="2008-04-29" version="1">MPELPEVEVTRQGVSPYLIDQEVTGLTVRNASLRWPVPDLAQQIVGQTIRSVHRRAKYLLIDTDAGTTIVHLGMSGSLRVVTELTPVEKHDHIDLSLASGKILRFNDPRRFGAWLWYELPIDAHPLLSKLGPEPLTDAFNPSYLFESLKGKKKAIKLCLMDNHIVVGVGNIYANEALFAAGIHPQMEAGKVDQERLIILVSEVKQILANAIKQGGTTLKDFTNAEGKPGYFAQKLHVYGRGGESCTQCGNLLSEIKLGQRATVFCGLCQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL65</accession>
    <name>B1KL65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diaminopropionate ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0105"/>
    <dbReference type="EnsemblBacteria" id="ACA84406">
        <property type="protein sequence ID" value="ACA84406"/>
        <property type="gene ID" value="Swoo_0105"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0105"/>
    <dbReference type="eggNOG" id="COG1171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_8_0_6"/>
    <dbReference type="OMA" id="WISQGYM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008838">
        <property type="term" value="F:diaminopropionate ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010081">
        <property type="entry name" value="DiNH2opropionate_NH3_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019871">
        <property type="entry name" value="DiNH2propionate_NH3-lyase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03528">
        <property type="entry name" value="2_3_DAP_am_ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01747">
        <property type="entry name" value="diampropi_NH3ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="36"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="393" mass="42534" checksum="B7B07B0FF6A96878" modified="2008-04-29" version="1">MMLKLTQNDFFNGETSELFTAQVAEQTRQFHQQIEAYQPTPLISLEQLAARLGVKAILVKDESYRFGLNAFKVLGGSYALGKQLAEHLNVDISEIDMKTVAAKLSEPLVFATATAGNHGTGVAWAAREMGQKAVVYMPKGSSQASVTRIQNLGAECIVTDCNYDDTVRIANQTATENGWMLVQDTAWEGYDKIPTWISQGYMTMAVEAQEQVDAMGLKPTHLMLQAGVGAMAGGILGYFADKVGATNFKTIIAEPAKADCIYNSGIKGEMVAVTGELNSIMAGLACGEPNPVTWPILKQCSSFFASVEDEVTATGMRILGNPLAGDTKIVSGESGALNLGLLYMLASREEYTEYRTQLGLDQDAIIMLFSTEGDTNPDRYRQIVWEGALSTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC2</accession>
    <name>B1KLC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1561</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1561"/>
    <dbReference type="EnsemblBacteria" id="ACA85847">
        <property type="protein sequence ID" value="ACA85847"/>
        <property type="gene ID" value="Swoo_1561"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1561"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_10_2_6"/>
    <dbReference type="OMA" id="QYRFFEL"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043968">
        <property type="entry name" value="SGNH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19040">
        <property type="entry name" value="SGNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="5"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH" evidence="3">
        <location>
            <begin position="430"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="643" mass="74188" checksum="59B0DF962C75CE2B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI2</accession>
    <name>B1KLI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flagellar protein export ATPase FliI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1621</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324253.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1621"/>
    <dbReference type="EnsemblBacteria" id="ACA85907">
        <property type="protein sequence ID" value="ACA85907"/>
        <property type="gene ID" value="Swoo_1621"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1621"/>
    <dbReference type="eggNOG" id="COG1157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022398_5_1_6"/>
    <dbReference type="OMA" id="MLMMDSV"/>
    <dbReference type="OrthoDB" id="875807at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020005">
        <property type="entry name" value="FliI_clade1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03496">
        <property type="entry name" value="FliI_clade1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="238"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="47972" checksum="6D99ECD1324D84DB" modified="2008-04-29" version="1">MHSRQNQLLNRIKQQSGKVHPFIAEASGQLVRVVGLTLEATGCRAPIGSLCSIETLAGELVAEVIGFDDELLYLMPIEELRGVLPGAKVTPLGEQSGLNVGLSLLGRVLDGNGLPLDGLGRLQTDQKAPRHAQSINPLSRRAITEPLDVGVRAINAMLTVGKGQRMGLFAGSGVGKSVLLGMMTRGTTADVIVVGLVGERGREVKEFIEEILGDEGRARSVVVAAPADTSPLMRLRACETSTRIAEYFRDLGYNVLLLMDSLTRYAQAQREIALAVGEPPATKGYPPSVFAKLPKLVERAGNGGSGQGSITAFYTVLTEGDDLQDPIADAARAILDGHIVLSRQLADSGHYPAIDIEASISRVAPMVISPEHLEAMRRVKQVYSLYQQNRDLISIGAYTQGSDPRIDNSIRLQPAMNAFLRQTMKEAIRFDSSELMLSQLGAQCKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLK4</accession>
    <name>B1KLK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CheW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324275.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1643"/>
    <dbReference type="EnsemblBacteria" id="ACA85929">
        <property type="protein sequence ID" value="ACA85929"/>
        <property type="gene ID" value="Swoo_1643"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1643"/>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048995_3_1_6"/>
    <dbReference type="OMA" id="FIQGVCH"/>
    <dbReference type="OrthoDB" id="1711729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="17919" checksum="4AF9B55929E86505" modified="2008-04-29" version="1">MTDANQVAVSKDDEVLQWVTFRLDNETYGINVMQVQEVLRYTEIAPVPGAPHYVLGIINLRGNVVTVIDTRSRFGLASSELDDSTRIVIIEAEKQVIGILVDSVAEVVYLRGSEIDNAPNVGTEESAKFIQGVSNRDNELLILVDLDKLLSDEEWMELTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLZ6</accession>
    <name>B1KLZ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4626</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0719 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327201.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4626"/>
    <dbReference type="EnsemblBacteria" id="ACA88876">
        <property type="protein sequence ID" value="ACA88876"/>
        <property type="gene ID" value="Swoo_4626"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4626"/>
    <dbReference type="eggNOG" id="ENOG5031PRF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_199156_0_0_6"/>
    <dbReference type="OMA" id="WDFLLAT"/>
    <dbReference type="OrthoDB" id="2012196at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007140">
        <property type="entry name" value="DUF350"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03994">
        <property type="entry name" value="DUF350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="75" mass="8295" checksum="D31D937DAB7BC7F2" modified="2008-04-29" version="1">MEITSLEQNVIFMLINLGYAVLSLFISVIALVVIDRFIFKDVDFIQEIKNGNIAVAIFQSVILLFIGVVVSSAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM64</accession>
    <name>B1KM64_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein CtaG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0176</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
            <orientation evidence="2">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX11/CtaG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322826.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0176"/>
    <dbReference type="EnsemblBacteria" id="ACA84477">
        <property type="protein sequence ID" value="ACA84477"/>
        <property type="gene ID" value="Swoo_0176"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0176"/>
    <dbReference type="eggNOG" id="COG3175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045000_5_2_6"/>
    <dbReference type="OMA" id="NKLECFC"/>
    <dbReference type="OrthoDB" id="1821272at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005413">
        <property type="entry name" value="COX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="SSF110111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20675" checksum="AD02A5B6E1868317" modified="2008-04-29" version="1" precursor="true">MEKAESNKKLISMLIAGAIGMFGFGFALVPLYDVLCEQLGINGKTSNTASSYQAMTIDKSRTVTVEFMAQIQSDMPWEFTPEMKRMQVHPGELIRTNFKAINLSMEETLGQAIPSVSPGQGAAYFNKTECFCFNQQRLTAKASAELPLIFFVDPDLPESISTLTLSYTLYNITDRGYVDAIEQGAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM73</accession>
    <name>B1KM73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322835.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0185"/>
    <dbReference type="EnsemblBacteria" id="ACA84486">
        <property type="protein sequence ID" value="ACA84486"/>
        <property type="gene ID" value="Swoo_0185"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0185"/>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_15_3_6"/>
    <dbReference type="OMA" id="VQSPHIQ"/>
    <dbReference type="OrthoDB" id="757027at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="70"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="406" mass="45102" checksum="36022F76DF6E0340" modified="2008-04-29" version="1">MLEGLAVWALFIYLLRLVGMPWNKFSKAFAYIGGGGWLLFVWVGLLNFTPMDLSGGSLVQSPHIQLRPASSQIKGSVKHIYVEPNQRIEQGQLVYELDDEPYQIALNKAKVDLNAAEVALKLANEDVKLAMKQHQSVLADTKISQSQVVAAQKDLSWKEKTLTRYVEQNRVVPDTITKSQLDEQQTAVALAQSQLASYVASVEKATFAEHKAGLEIEKAHLAVASRQSDLAGQAETLAKAQWDLDSTKVYAPADGYLTNFIMREGQFVGLVPRIAMYTDEKYVLMRVNHQAIRNVKVGQSAEFASAVYPGKVFRAQVEGIVEATGEAQGSLLARDDNVRQTTGQNLNNKHHFVRLKLEEGEYDLPVGAVGLAWISAEKPTALLSFLDVIRGIIIRMKSQIYYFYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMF0</accession>
    <name>B1KMF0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.14" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324294.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1662"/>
    <dbReference type="EnsemblBacteria" id="ACA85948">
        <property type="protein sequence ID" value="ACA85948"/>
        <property type="gene ID" value="Swoo_1662"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1662"/>
    <dbReference type="eggNOG" id="COG0381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041674_0_0_6"/>
    <dbReference type="OMA" id="RYNTERP"/>
    <dbReference type="OrthoDB" id="1117971at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="29"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="376" mass="42580" checksum="3224C19A4D5466AF" modified="2008-04-29" version="1">MKRLKVVTVVGTRPEIIRLSCTIAKLDEFCEHVLVHTGQNYDYELNQIFFEDLGIRAPDIFLECAGATAAETMAQVISKADAMFADVQPDAILILGDTNSAMAAIPAKRRKIPIFHMEAGNRCFDMRVPEEINRKIVDHTADVNMPYTDIAREYLLAEGLKPDLIVKTGSPMDEVLHRYSDKIANAEILTTLGLTSGEYFVVSVHREENVDSEKNIHSYVDALNVIAEKYQYPIIVSTHPRTRKKIDLLKLEFHPLVKLLKPLGFSDYVKLQMDAKVVLSDSGTITEESSILNFPAINIRDAQERPEGFEEGAVMFTGMNVERILQAIEILNKQPRGEERLIKKVQNYIAPNVSDKVLRTIISYTDYVDRVVWRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG3</accession>
    <name>B1KMG3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324307.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85961">
        <property type="protein sequence ID" value="ACA85961"/>
        <property type="gene ID" value="Swoo_1676"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1676"/>
    <dbReference type="eggNOG" id="ENOG5031V4K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1650972_0_0_6"/>
    <dbReference type="OMA" id="RFETATI"/>
    <dbReference type="OrthoDB" id="2170724at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767487" evidence="1">
        <location>
            <begin position="26"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="160" mass="17516" checksum="F2CE768B2DFFDCB1" modified="2008-04-29" version="1" precursor="true">MKKPSATPLFLAVLLSIALPNTSVAKTIVASSSELDISTLSSEKRFETATITITGPNGFEKQFILSGNDTELDLGQLGITQDGNYSYQIEYAQPGKVETINDPRTGRSGSKRNLGKVETKSGYFNVKDSEFVHEEYSEGLEKAEEIDTNNFEIVDENLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG4</accession>
    <name>B1KMG4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Conserved repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1677</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324308.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1677"/>
    <dbReference type="EnsemblBacteria" id="ACA85962">
        <property type="protein sequence ID" value="ACA85962"/>
        <property type="gene ID" value="Swoo_1677"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1677"/>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4257">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_230860_0_0_6"/>
    <dbReference type="OrthoDB" id="410764at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044048">
        <property type="entry name" value="Big_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19078">
        <property type="entry name" value="Big_12"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766844" evidence="2">
        <location>
            <begin position="33"/>
            <end position="2233"/>
        </location>
    </feature>
    <feature type="domain" description="CADG" evidence="3">
        <location>
            <begin position="1221"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="domain" description="CADG" evidence="3">
        <location>
            <begin position="1316"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="domain" description="CADG" evidence="3">
        <location>
            <begin position="1408"/>
            <end position="1500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="2233" mass="227521" checksum="CE4D86AB04DCE750" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ3</accession>
    <name>Y1706_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable phosphatase Swoo_1706</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1706</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 3 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHP family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324337.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMJ3"/>
    <dbReference type="SMR" id="B1KMJ3"/>
    <dbReference type="STRING" id="392500.Swoo_1706"/>
    <dbReference type="PRIDE" id="B1KMJ3"/>
    <dbReference type="EnsemblBacteria" id="ACA85991">
        <property type="protein sequence ID" value="ACA85991"/>
        <property type="gene ID" value="Swoo_1706"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1706"/>
    <dbReference type="eggNOG" id="COG1387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061999_0_1_6"/>
    <dbReference type="OMA" id="SEPNCRA"/>
    <dbReference type="OrthoDB" id="1615112at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01561">
        <property type="entry name" value="YcdX_phosphat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023710">
        <property type="entry name" value="Phosphatase_YcdX_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000147148" description="Probable phosphatase Swoo_1706">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01561"/>
        </source>
    </evidence>
    <sequence length="249" mass="27364" checksum="DDB995882AB5DE0E" modified="2008-04-29" version="1">MQYLVDVHAHTIASTHAYSTIHDYISVAKEKGLKLFAVTDHGPDMADAPHFWHFVNMRVLPRLVDGIGILRGIEANIKNRDGEIDFFGDYLKELDIVLAGFHEPVFPPSDRQTHTQAMISTIESGNVDIITHPGNPAYPIDIDKVAEAAAKHNVALEINNSSFLASRKGSEGNCIAIARAVHDAGGLLVMGSDSHISFSLGGFEQAILVIREAEFPEERLLNRSPQALLSFLSERGHDSLDEYSVLLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMS9</accession>
    <name>B1KMS9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease H</fullName>
            <ecNumber evidence="5">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3186</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase H family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325793.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3186"/>
    <dbReference type="EnsemblBacteria" id="ACA87457">
        <property type="protein sequence ID" value="ACA87457"/>
        <property type="gene ID" value="Swoo_3186"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3186"/>
    <dbReference type="eggNOG" id="COG0328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3341">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030894_0_4_6"/>
    <dbReference type="OMA" id="ELWYGLY"/>
    <dbReference type="OrthoDB" id="1953872at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09278">
        <property type="entry name" value="RNase_HI_prokaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017067">
        <property type="entry name" value="RNase_H1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022892">
        <property type="entry name" value="RNaseHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036852">
        <property type="entry name" value="Ribonuclease_H1_euk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="7">
        <location>
            <begin position="78"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="251" mass="27868" checksum="5DC7A0E9C6512A6E" modified="2008-04-29" version="1">MASKYYVVWVGRTPGIYTSWDEAKKQVDKYPKAKYKSYKSKTEAETAYAKGSTQVSYSKKSTSSAQTPASLSNPADDTQYNVEIFTDGGCEPNPGKAGSGVAVYREGVLAELWYGLYNSFGTNNSAELNALHQALLMAKQALIENKTVHIRSDSQYSINCITNWAYGWKQKGWKRKVAGDIKNLDIIQAAHALYDEIKDQLKISHVAAHIGIEGNELADRMSIYAIDQQDSKFCRYPEPIELSAILSLRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMU2</accession>
    <name>B1KMU2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325806.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3200"/>
    <dbReference type="EnsemblBacteria" id="ACA87470">
        <property type="protein sequence ID" value="ACA87470"/>
        <property type="gene ID" value="Swoo_3200"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3200"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_6"/>
    <dbReference type="OMA" id="NMATWML"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="121"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="227"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="385" mass="41931" checksum="ACF0629580F89707" modified="2008-04-29" version="1">MDFNLNDDQRQFADLAQQFSSEELAPFAAKWDEEHHFPKDVIQRAGELGFCSLYSPESEGGMGLSRLDSSIIFEQLSMGCTATTAMLTIHNMATWMLTSFGSETLRAQWSESLTTGEKLASYCLTEAGAGSDAASLKTKAVREGDEYVISGAKMFISGAGATELLVVMCRTGEAGPKGISAIAVPADADGITYGKAEDKMGWNAQPTREITFTEVRVPVANLLGEEGQGFTFAMKGLDGGRINIATCSIGTAQAALERATQYMTERKQFGKPIAAFQALQFKLADMATELVAARQLVRLAAFKLDQQDPEATAYCAMAKRFATDIGFQVCDAALQLHGGYGYIREYPLERHVRDVRVHQILEGTNEIMRLIIARRLLNEEAGAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN64</accession>
    <name>B1KN64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322910.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0260"/>
    <dbReference type="EnsemblBacteria" id="ACA84561">
        <property type="protein sequence ID" value="ACA84561"/>
        <property type="gene ID" value="Swoo_0260"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0260"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_1_1_6"/>
    <dbReference type="OMA" id="FFEHLLF"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767516" evidence="3">
        <location>
            <begin position="24"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="43"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="194"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="443" mass="49211" checksum="6179A01DAB84ACD4" modified="2008-04-29" version="1" precursor="true">MIGRLTGLVMAAGVLFTSAAVQATEAKDISSFTLDNGMKIMVLEDASIPNANMYLFWKVGSRNEVPGITGISHFFEHMMFNGSEKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPSNAIETIFDLEADRIGKLDIDAKMVESERGVVASERLTGLENSNWRTLQEELKGAAFRAHPYSWSVIGHESDIAAWSLDDLVQYHKTYYAPNNAVVVIAGDVKLAEVKALADKYFAPIPAQAPPKEVKTVEPLQKGERRVFVQKASVSTPNVMLGYHVPATSHQDYYALNLLSNILSTGNSSRLYQSLVEKQLALEVMAYLPMTIDPNLFYVMAVANPGVTAKELELNLIAEINRVARDGVTEQELEKVKNIKLMEFYRSMETINGKANTIGTYELYFGSFDKLFNAPEAYNKVTTADIQRVAQIYLRRANRTVAVLAATEEADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN73</accession>
    <name>B1KN73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322919.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0269"/>
    <dbReference type="EnsemblBacteria" id="ACA84570">
        <property type="protein sequence ID" value="ACA84570"/>
        <property type="gene ID" value="Swoo_0269"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0269"/>
    <dbReference type="HOGENOM" id="CLU_2169369_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="12612" checksum="0407A579758CA2C2" modified="2008-04-29" version="1">MELDFYKGFECVDSVSVGKELWGDILKIECLDEVSSDESIIPDGFDGEGEKIERISLLEIRKSMLESLSRLLLKNSRLERDENTIVALSKIIEIMRFINSDDISHFKLDV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KND6</accession>
    <name>ASSY_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Argininosuccinate synthase</fullName>
            <ecNumber evidence="1">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argG</name>
        <name type="ordered locus">Swoo_0332</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322982.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KND6"/>
    <dbReference type="SMR" id="B1KND6"/>
    <dbReference type="STRING" id="392500.Swoo_0332"/>
    <dbReference type="EnsemblBacteria" id="ACA84633">
        <property type="protein sequence ID" value="ACA84633"/>
        <property type="gene ID" value="Swoo_0332"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0332"/>
    <dbReference type="eggNOG" id="COG0137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032784_4_2_6"/>
    <dbReference type="OMA" id="QCEVVTF"/>
    <dbReference type="OrthoDB" id="357142at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="Argininosuccinate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0055">Arginine biosynthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000089053" description="Argininosuccinate synthase">
        <location>
            <begin position="1"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="16"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00005"/>
        </source>
    </evidence>
    <sequence length="408" mass="44705" checksum="2186E3E2042711C2" modified="2008-04-29" version="1">MSAEIKKTGVKKVVLAYSGGLDTSAIIPWLKETYDDCEIVAFCADVGQGEAELEGLHEKAIASGASECYIVDLKEELVADYIYPTIATGAIYEGTYLLGTSMARPIIAKAQVEVARKVGADAVCHGCTGKGNDQVRFEGCFAALAPDLKVIAPWREWEMVSREDLLDYLAERNIETTASATKIYSRDANAWHISHEGGELEDPWNEPTKGVWTMTVAPEDAPDKPEYVTIDIEQGKITKVNGELLSPYAALMVLNEIAGAHGVGRIDITENRLVGMKSRGCYETPGGTVMFAALRAIEELVLDKSSREWREQVGAQMAHLVYDGRWFTPLCESLLGASQPLANLVNGEVVIKLYKGQAQAVQKRSPNSLYSEEFATFGEDDVYNQKDAEGFIRLYSLASRIRALNSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNN4</accession>
    <name>B1KNN4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325828.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3222"/>
    <dbReference type="EnsemblBacteria" id="ACA87492">
        <property type="protein sequence ID" value="ACA87492"/>
        <property type="gene ID" value="Swoo_3222"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3222"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_3_1_6"/>
    <dbReference type="OMA" id="HTMLELV"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="132" mass="15463" checksum="8C90C600A66C323A" modified="2008-04-29" version="1">MSDKQITQTTYSISDLSKEFDITTRSIRFYEDQGLLKPKRRGQTRIYNLKDRVRLKLILRGKRLGFSLAETRRLFELYDADKNSVSQLHTMLELVEEKKTSLQQQMDDIKVVLMELNSAEQQCRAALENSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP39</accession>
    <name>B1KP39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327387.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA89070">
        <property type="protein sequence ID" value="ACA89070"/>
        <property type="gene ID" value="Swoo_4821"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4821"/>
    <dbReference type="eggNOG" id="ENOG5032CG9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166182_0_0_6"/>
    <dbReference type="OMA" id="IAFRNAP"/>
    <dbReference type="OrthoDB" id="1792211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="114" mass="13441" checksum="006BE6653A516289" modified="2008-04-29" version="1">MVFERVQKQSHKVADSELTVSYDRFTTRFTIKAAEEVLHSSLLMFIPIRNKELSINNQLFTLKIRWLILWQSKLENSQGVVIKELLYLRRRKSINLFIYLILITSIKAGIILFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPA3</accession>
    <name>B1KPA3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TraR/DksA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0374</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323022.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0374"/>
    <dbReference type="EnsemblBacteria" id="ACA84673">
        <property type="protein sequence ID" value="ACA84673"/>
        <property type="gene ID" value="Swoo_0374"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0374"/>
    <dbReference type="eggNOG" id="COG1734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158637_0_1_6"/>
    <dbReference type="OMA" id="MAGGWAR"/>
    <dbReference type="OrthoDB" id="1932026at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="5">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA84673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="88" mass="9718" checksum="08C81234EA807EE3" modified="2008-04-29" version="1">MAGGWSRDGAVQDQIDNSVDDGVAQARSRLPVGQSLLYCEECDSPIPQARREAVIGVRLCVSCQQEADKQFKSFSNFNRRAGKDSQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPC7</accession>
    <name>B1KPC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323046.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0398"/>
    <dbReference type="EnsemblBacteria" id="ACA84697">
        <property type="protein sequence ID" value="ACA84697"/>
        <property type="gene ID" value="Swoo_0398"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0398"/>
    <dbReference type="eggNOG" id="ENOG5033HU2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177056_0_0_6"/>
    <dbReference type="OMA" id="ICWLSVE"/>
    <dbReference type="OrthoDB" id="1848692at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022080">
        <property type="entry name" value="DUF3630"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12305">
        <property type="entry name" value="DUF3630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="97" mass="11415" checksum="3EA5A605D282FD74" modified="2008-04-29" version="1">MKLQSISLDPTSKSLSIVADIDFEAFELFAEPLSRAIDARVIERQWGADRHQWLLDFEGTQIQLNYEFYGDICWLSVERDDEFEVLEFLASLLERQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD6</accession>
    <name>B1KPD6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0407"/>
    <dbReference type="EnsemblBacteria" id="ACA84706">
        <property type="protein sequence ID" value="ACA84706"/>
        <property type="gene ID" value="Swoo_0407"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0407"/>
    <dbReference type="eggNOG" id="ENOG5031H73">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1863806_0_0_6"/>
    <dbReference type="OMA" id="CGCANLV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="146" mass="16221" checksum="EC51B5B9D8169AA7" modified="2008-04-29" version="1" precursor="true">MLLVFSLLKNIKIIIMIKSSFKGRSIRKAITISGLSLVLCGCANLVHTQKDTQSNIDVTELGLYWVVKDGVLDWSVFSDDEVQHSFTAQFTINPEGKIEALKLSENQAGFNPSESQIAEFPKQEFNATTANYEKQAVTVSMFIGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPD9</accession>
    <name>B1KPD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mg chelatase, subunit ChlI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323058.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0410"/>
    <dbReference type="EnsemblBacteria" id="ACA84709">
        <property type="protein sequence ID" value="ACA84709"/>
        <property type="gene ID" value="Swoo_0410"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0410"/>
    <dbReference type="eggNOG" id="COG0606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026145_1_1_6"/>
    <dbReference type="OMA" id="STNPCPC"/>
    <dbReference type="OrthoDB" id="581802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="213"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="507" mass="55677" checksum="EC03916D7E9669CE" modified="2008-04-29" version="1">MAIACVATRASKGVDAPSVTVEVHLSNGLPAFNLVGLPETSVKEAKERVRSAIINAGFEFPMRRITVNLAPADLPKQGGRYDLPIAIGILVASKQIPEKAIKDHEFVGELALSGHIRQSQGLLPVIVEARQQGINLVLPLENRADAELVGYNRVYFASHLQGLSEYLHGQSRLPGIESGLEWIEHEKEESQSCFSEVIGQYHAKHGLEIAAAGNHNILLLGPPGTGKSMLASRMMQLLPPLGYDEALEVATLHSVAGHQIHPNAFYTRPFRNPHHTSSAISLVGGGSVPRPGEISLAHRGVLFLDEVVEFPRKVLDCLREPMETGEVVISRAAAKLTFSSRFQLIAAMNPSPCGDLDNARATPDQIQRYLSRLSGPFLDRFDLTIEVPRLPAGALTQENKNAETSSTIAQRVKLARERQLNRAGVLNSELSGKQLKDLGRFKQADLLFLEQSVNKLNLSIRSFHRLQRVSRTIADLQQSENVERNHIAQALGYRAMDRLLNSLKTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPF7</accession>
    <name>B1KPF7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324456.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1826"/>
    <dbReference type="EnsemblBacteria" id="ACA86110">
        <property type="protein sequence ID" value="ACA86110"/>
        <property type="gene ID" value="Swoo_1826"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1826"/>
    <dbReference type="eggNOG" id="ENOG502Z91X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_926328_0_0_6"/>
    <dbReference type="OMA" id="ALMAQFY"/>
    <dbReference type="OrthoDB" id="721251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="33699" checksum="9CDC8200B5C6DC4B" modified="2008-04-29" version="1">MQIVLRDNDQGPFLSKVLAYGQAESLLDEAQLAQIKAKAVLMSLKLADKFYNKYKMHLLEHAAFDVIGVVSLGLMEQSERDLNRGLSLLMTADGIVKSFQKGWSMLTTVSKYKLSGKSIYGDIDKVLLEKVSCPSDAQEWSGWQAYQEALSDFNRQESVVSLLRQFYSQASYDPLDCLSLESVFAEVVLYRLFFGPVKIKQDLKQRLAHIELEEHWFTLDHIELEMNNTLGELPPALAETISVDLGKYFAPGLLRTLTFAKGYREQLLKGVSPERLERLEYKEGLTGLLGWPIYIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH4</accession>
    <name>B1KPH4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent protein deacylase</fullName>
            <ecNumber evidence="3">2.3.1.286</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Regulatory protein SIR2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobB</name>
        <name evidence="5" type="ordered locus">Swoo_1843</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:47668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:11877"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:87830"/>
            <dbReference type="ChEBI" id="CHEBI:87832"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sirtuin family. Class III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324473.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1843"/>
    <dbReference type="EnsemblBacteria" id="ACA86127">
        <property type="protein sequence ID" value="ACA86127"/>
        <property type="gene ID" value="Swoo_1843"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1843"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_1_6"/>
    <dbReference type="OMA" id="SMQVYPA"/>
    <dbReference type="OrthoDB" id="1264438at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034979">
        <property type="term" value="F:NAD-dependent protein deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036054">
        <property type="term" value="F:protein-malonyllysine demalonylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036055">
        <property type="term" value="F:protein-succinyllysine desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006476">
        <property type="term" value="P:protein deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01412">
        <property type="entry name" value="SIRT5_Af1_CobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01121">
        <property type="entry name" value="Sirtuin_ClassIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027546">
        <property type="entry name" value="Sirtuin_class_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="176"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="202"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="28260" checksum="4952F4C084E2F10C" modified="2008-04-29" version="1">MYRQIVILTGAGISAESGLRTFRDQDGLWEEHKIEDVATPEGYARDPELVEAFYNTRWSQLHNGDVEPNEGHLALAKLEKEFDGELLVVTQNIDDLHERAGSRRLLHMHGELSKGRCPRSRQTFILKDPFGPAHTCTCCIPAQRLRPHVVWFGEMPIGLDRIQHALDSCDLFIAIGTSGTVYPAAGFVDTANHHGAQTIEVNLVEADRHSQFQYHLQGKASQVLPELVDKILKGQVISNSSCDVTDSLVLKSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPH8</accession>
    <name>B1KPH8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycine betaine/L-proline ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1847</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324477.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1847"/>
    <dbReference type="EnsemblBacteria" id="ACA86131">
        <property type="protein sequence ID" value="ACA86131"/>
        <property type="gene ID" value="Swoo_1847"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1847"/>
    <dbReference type="eggNOG" id="COG4175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_2_2_6"/>
    <dbReference type="OMA" id="RRDMQEE"/>
    <dbReference type="OrthoDB" id="1713578at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031460">
        <property type="term" value="P:glycine betaine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005892">
        <property type="entry name" value="Gly-betaine_transp_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01186">
        <property type="entry name" value="proV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="35"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="342"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="67"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="413" mass="45948" checksum="A061F94B9ACBD930" modified="2008-04-29" version="1">MSNKVKIEPLIEIKDLYKVFGKKPASVMPMVREGLSKDDILAQTGHTVGLKAINLDVYKGEIFVIMGLSGSGKSTLIRHFNRLIDPTEGQILVEGTDVMKLNTKELETFRRKKMAMVFQRFGLMPHRNVQDNVAYGLSVQGVDKATRVDKANKWLETVGLAGYEKQYPSQLSGGQQQRVGLARALCTDAEILLMDEAFSALDPLIRSEMQDQLVELQKELSKTIIFITHDLDEALRIGDRIAILKDGDLIQLGEPVDILLNPADDYVEAFVKDVNRARALTVDTVMKPPAYRLTAETIGEALKEMRQNSANYAYYMTEEGFQGVVCEKALESAAEDNAAAPMDEFKVEEMSVLSPDAPLESIIPATMKSDFPMPVVDDDGDLQGLLSREDLAEVLSDFYKDEKDEVVTESKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPP9</accession>
    <name>B1KPP9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3313</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3313"/>
    <dbReference type="EnsemblBacteria" id="ACA87582">
        <property type="protein sequence ID" value="ACA87582"/>
        <property type="gene ID" value="Swoo_3313"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3313"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_10_6"/>
    <dbReference type="OMA" id="MKTHTTR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="146"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="38149" checksum="48F2108C37BD4595" modified="2008-04-29" version="1">MDKSMVEKATVLVVDDTPENIDVLAGVLRDLYKVKVARNGEIALKITRSPSPPDLILLDVMMDGIDGYEVCRQLKEDHSTRHIPIIFVTAKIAQEDEVKGFELGAVDYISKPISPAIVLSRVKTHLALYNQNRELDRKVLEKTQEISDNQLKVVQRLGRAAEYKDNETGMHVIRMSHYTYVLALATGMSEKDAETLRVAAPMHDVGKIGIPDSILQKQGKLDEDEWQVMLTHAEIGAEILGDDSSEMLSIARTVALSHHEKWDGSGYPYGLKGEAIPMVGRIVAIADVFDALTSIRPYKQAWSVDEALGLLKEESGRHFDPSLVTLFIACIDDILEIKSKFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPT2</accession>
    <name>B1KPT2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase D</fullName>
            <ecNumber evidence="4">5.4.99.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(13) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truD</name>
        <name evidence="6" type="ordered locus">Swoo_3346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>uridine(13) in tRNA = pseudouridine(13) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10105"/>
            <dbReference type="Rhea" id="RHEA-COMP:10106"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.27" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325950.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3346"/>
    <dbReference type="EnsemblBacteria" id="ACA87615">
        <property type="protein sequence ID" value="ACA87615"/>
        <property type="gene ID" value="Swoo_3346"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3346"/>
    <dbReference type="eggNOG" id="COG0585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005281_4_0_6"/>
    <dbReference type="OMA" id="LWLWVEK"/>
    <dbReference type="OrthoDB" id="1490777at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01082">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043165">
        <property type="entry name" value="TruD_insert_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="5">
        <location>
            <begin position="152"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="355" mass="40079" checksum="17300A73B406FBC5" modified="2008-04-29" version="1">MIELHYLHGKPTSKADLRTHNSDFQVQEILPFAPTGEGEHHLLHIRKEGLNTNDVATLLSGFAHVHPKEVTYAGQKDKNAITEQWFGVRIPGKETPDWASLNSEQLTVLSSSRHSKKLRIGALAGNRFSLTLRNVTKMNEVIERLELIKQTGVPNYFGEQRFGHDGKNLVFGRQMLTGRKVKDRKKRSIYLSAVRSYLFNISVSARLAEHGLNKLDGDCVMLAGTKSYFTAEQWDDATIKRLDEKDIQLSAPLWGRGAALSQADAAEFEAKALAEFESDRDGLEHAGLIQERRTLLSEPQHLSYEQEGDDTLLIKFALPAGCYATSVLRELFDYEDVKEREFRERQQARQASAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPY0</accession>
    <name>B1KPY0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325998.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3395"/>
    <dbReference type="EnsemblBacteria" id="ACA87663">
        <property type="protein sequence ID" value="ACA87663"/>
        <property type="gene ID" value="Swoo_3395"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3395"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_34_0_6"/>
    <dbReference type="OMA" id="GAIFKGH"/>
    <dbReference type="OrthoDB" id="1360387at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20574" checksum="BE04B5E5DAA87F61" modified="2008-04-29" version="1" precursor="true">MSSSLSLKSIFILLSVNLGVSVLVSLLYVSYSLASPLELDKKHNLAQNHLSSQKDENRDAQLLMDYFFAAARTGDVEVLTHFIEAGFPIDQRNNQSYTALMVSAYNGQELATQALLDHGANACLQDKRGNTAIMGAVIKAEFSIIKQLYSQECNAELTNKSGMTLDDFAQYWGQSDKLRDASLAAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ95</accession>
    <name>B1KQ95_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent copper receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0452</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323099.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84750">
        <property type="protein sequence ID" value="ACA84750"/>
        <property type="gene ID" value="Swoo_0452"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0452"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014873_2_1_6"/>
    <dbReference type="OMA" id="GWFGDGN"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010100">
        <property type="entry name" value="TonB-dep_Cu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01778">
        <property type="entry name" value="TonB-copper"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767555" evidence="5">
        <location>
            <begin position="27"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="70"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="207"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="662" mass="72599" checksum="B79458E38CECA877" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD8</accession>
    <name>B1KQD8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0495</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323142.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0495"/>
    <dbReference type="EnsemblBacteria" id="ACA84793">
        <property type="protein sequence ID" value="ACA84793"/>
        <property type="gene ID" value="Swoo_0495"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0495"/>
    <dbReference type="eggNOG" id="COG3550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041102_1_0_6"/>
    <dbReference type="OMA" id="HPFNEHA"/>
    <dbReference type="OrthoDB" id="1293681at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="18"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="162"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="411" mass="46058" checksum="B39719BE532483F1" modified="2008-04-29" version="1">MLETPLRVNRTFSDGSKAHIGTLAENRAGTYFQFDENYLAQHPTSIAPFNIKADLTLQKAPKQPHYGIHGVFGDSLPDGWGLHLMDRVFRQNGYNPQLITALERLAYIGDQCLGALSYEPEMHLLEADSRDVELVTLGQEAVKEFEGTESKLIEQLMNAAGSGGARPKLNVTKTSDGQFSTHANATGEKLIVKLTSEKFDLKHSESLVEYAYMQMASNLGIETPKFELIEASAGRMWLQQTRFDCTPQGKRHMISACGLLDAPFREPSLDYVDLVKATRMLCGVGEARKLVKRALFNFITVNQDDHAKNFAFLADDNDQWRLSPFYDIVYSPSPYKQHMTSFNGNGSSPKQALNILAGQAGYSSDKPLREMLEEIYQQSRSFTQEAKNLGIPNQLLTSIDNQMTEKWNSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE5</accession>
    <name>B1KQE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EcoEI R domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323149.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0503"/>
    <dbReference type="REBASE" id="17472">
        <property type="entry name" value="SwoAIP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84800">
        <property type="protein sequence ID" value="ACA84800"/>
        <property type="gene ID" value="Swoo_0503"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0503"/>
    <dbReference type="eggNOG" id="COG4096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018958_0_0_6"/>
    <dbReference type="OMA" id="DGFIFHD"/>
    <dbReference type="OrthoDB" id="16977at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006304">
        <property type="term" value="P:DNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013670">
        <property type="entry name" value="EcoEI_R_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08463">
        <property type="entry name" value="EcoEI_R_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="190"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="824" mass="93511" checksum="70661814AD9F4D7C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE7</accession>
    <name>B1KQE7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase B</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dusB</name>
        <name evidence="14" type="ordered locus">Swoo_0505</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10 11">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10 11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Dus family. DusB subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323150.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0505"/>
    <dbReference type="EnsemblBacteria" id="ACA84802">
        <property type="protein sequence ID" value="ACA84802"/>
        <property type="gene ID" value="Swoo_0505"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0505"/>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_0_1_6"/>
    <dbReference type="OMA" id="RPWLFAD"/>
    <dbReference type="OrthoDB" id="1710586at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02042">
        <property type="entry name" value="DusB_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032887">
        <property type="entry name" value="DusB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="9 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="13">
        <location>
            <begin position="13"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="16"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="200"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA84802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="322" mass="35812" checksum="36937AC1594FF1B0" modified="2008-04-29" version="1">MQIGPYQLKNQLIVAPMAGVTDQAFRNLCLRYGAAMAVSEMLSSNPDVWDTDKSRQRMLHAGEDGIRSVQIAGADPELMANAAVVNVQQGAQIIDINMGCPAKKVNRKLAGSALLQDPVQVKAILQAVVAAVDVPVTLKIRTGWAPEHRNGVQIAQIAEDCGIAALAVHGRTRQCMYKGNAEYDTIKAIKKNVSIPVVANGDITTPQKAQFVLEHTGVDALMIGRGAQGRPWIFREIQHYLETGNMLAPVEVDEKRQVMLEHLKNLYSLYGEYKGIRFARKHVGWYLDQDEQRPFRAEFNRLETVEEQGSMVERYFDEIAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM3</accession>
    <name>B1KQM3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1978</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324608.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1978"/>
    <dbReference type="EnsemblBacteria" id="ACA86262">
        <property type="protein sequence ID" value="ACA86262"/>
        <property type="gene ID" value="Swoo_1978"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1978"/>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_0_0_6"/>
    <dbReference type="OMA" id="NMAYFTP"/>
    <dbReference type="OrthoDB" id="1413173at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="6">
        <location>
            <begin position="18"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="116"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="371" mass="39200" checksum="56E8A7DCCD57E60D" modified="2008-04-29" version="1">MSSASQDYRLSDELLGPVLAILDAYQDPYLAQGLVSAGCVSKLSIDGKRLQLGLCYPYPCMTQYRDTVMAITKKLAVLDAIDEVECEIDFQPASISAISTVEPIPNVKQVIAVASGKGGVGKSTTSVNLALALAAEGAKVGILDADIYGPSIPLMLGVSDFRPVSADGKMMSAATAHGISAQSIGFMLADDEAAVWRGPMAAGALAQLLNETLWPELDYLVIDMPPGTGDIQLTLSQKVPVTGAVVVTTPQDIALADAKKGISMFQKVNIPVLGIVENMSFHMCSECGHKEHPFGSHGGSKMAQRYQVPLLGELPLKLNIREDVDNGKPTVVADPDSEVAALYREIARKVGAQLALTKVQSTVSISISDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQP2</accession>
    <name>B1KQP2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1997"/>
    <dbReference type="EnsemblBacteria" id="ACA86281">
        <property type="protein sequence ID" value="ACA86281"/>
        <property type="gene ID" value="Swoo_1997"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1997"/>
    <dbReference type="eggNOG" id="COG3347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066010_0_0_6"/>
    <dbReference type="OMA" id="MWIKASG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="5"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="337" mass="37549" checksum="E4F2203A09A6D5FF" modified="2008-04-29" version="1">MSVQELAQISAKYGRNLSLVQGAGGNTSYKCYQSDCMWIKASGKWLGNALNENIFIPLKLSELKRSFLLEPTSSLDHHVMEHTVESGLRPSIETSMHALLPHKFVVHLHSTSVLAWLVQKNIESNIAGRLTGLHWCLIDYVKPGAALTESILNTIKQDTNIILLKNHGVVILGKSVTEIEQLVREVESRLYCPKRSTTPYANIANLLALSAGSDYRLPSYPDIHSLALNKNSYRTAKKGPLFPDQVVFLGESIKTITKSIVKDKNPVNSPQMLLMEGKGVLINKHVCKTGEQLAYGLSSVLLKLPEKHVIRYLSDSEIMELTNWDAETYRHSMTSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR12</accession>
    <name>B1KR12_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323177.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0532"/>
    <dbReference type="EnsemblBacteria" id="ACA84829">
        <property type="protein sequence ID" value="ACA84829"/>
        <property type="gene ID" value="Swoo_0532"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0532"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_10_2_6"/>
    <dbReference type="OMA" id="VFWYVLM"/>
    <dbReference type="OrthoDB" id="1930882at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="57"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20729" checksum="22408152115747D8" modified="2008-04-29" version="1">MFTKLVKLDRRLFNYLFAQSEARKLGVLARRLSRTGDGPLYLFLVFIVMISHAKGEMLFYLALAGFTVELPLYLILKNTIKRTRPCHLELSSCDSGYSPLTDKHLMALKRFEPSDKFSLPSGHTAGAFVMATSVAFIYPQWGYLVYLWALLVGGSRIALGVHYPLDILAGAALGTGSVFAILSIGFD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRB5</accession>
    <name>RL32_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmF</name>
        <name type="ordered locus">Swoo_2038</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324668.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRB5"/>
    <dbReference type="SMR" id="B1KRB5"/>
    <dbReference type="STRING" id="392500.Swoo_2038"/>
    <dbReference type="EnsemblBacteria" id="ACA86322">
        <property type="protein sequence ID" value="ACA86322"/>
        <property type="gene ID" value="Swoo_2038"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2038"/>
    <dbReference type="eggNOG" id="COG0333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129084_2_1_6"/>
    <dbReference type="OMA" id="GMHRAHD"/>
    <dbReference type="OrthoDB" id="2092354at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000120172" description="50S ribosomal protein L32">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="56" mass="6311" checksum="9222ED85B1C82FFE" modified="2008-04-29" version="1">MAVQQNKKSRSKRGMRRSHDSLSTAQLSVDATSGELHRRHNVTADGFYRGVKVINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRC8</accession>
    <name>B1KRC8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">rRNA (Guanine-N(1)-)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2051</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2051"/>
    <dbReference type="EnsemblBacteria" id="ACA86335">
        <property type="protein sequence ID" value="ACA86335"/>
        <property type="gene ID" value="Swoo_2051"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2051"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050931_0_0_6"/>
    <dbReference type="OMA" id="MTPHGWR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016718">
        <property type="entry name" value="rRNA_m1G-MeTrfase_A_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018249">
        <property type="entry name" value="MyrA_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="3">
        <location>
            <begin position="89"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="99"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR018249-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR018249-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="274" mass="31391" checksum="3686750D0D44546B" modified="2008-04-29" version="1">MEEKMNYLCPICKQPLLLQEKTWSCLSNHRFDCAKEGYVNLLPVQNKGSKDPGDNKEMMFARREFLNKGHYQGLSDRINTLAKTYAKAAKNGLDIGCGEGYYSHRLQECLSTSNEFKLKGLDISKSALKYASKRYKAIDFCVASAFEMPFADNCFDLMLRVYAPSLDEELRRVVKTDGILITASAGEQHHFALKQLIYAEPKPHMSESSQIQGFELLHRENLESLMVLEDESDITHFLNMTPYSWKLTDEQKSQLVQEGLKCELDFKIEVFKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRI0</accession>
    <name>B1KRI0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-containing alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324732.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2103"/>
    <dbReference type="EnsemblBacteria" id="ACA86387">
        <property type="protein sequence ID" value="ACA86387"/>
        <property type="gene ID" value="Swoo_2103"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2103"/>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007207_0_0_6"/>
    <dbReference type="OMA" id="AKAMWIK"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="10"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="388" mass="41146" checksum="9C68B0D0392ECEA8" modified="2008-04-29" version="1">MDLHANWNFPTNITVGEGCLSQLGEQCKALKMTKVLLITDPGLADLPMVKEAMGYCTQAGLMVELFSDIQGNPTGDNVRAGAICLKSGGFNGVVAFGGGSSLDAAKAIAMIAKQSLSLWSTEDVGDNWTRIDERLMVPVVAVPTTAGTGSEVGRASVITDTDGAHHVKRIIFHPKMLPATVLLDPKLTLGLPPPITAATGLDALSHSLEAYCAPSYHPMAEGIAIEGIRLVKDYLPRAVANGEDIEARTQMLVASSMGATSFQRGLGAMHAIAHSLGALYDKHHGLLNAILMPYVLKRNRAQIEKKIIRLSQYLELDNPNSDGFMDWILALRAELNIPHTLADIGITLADVVLVGKMAAKDAAAGGNPITLTDAEYSLLFSDAVKGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRL1</accession>
    <name>B1KRL1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase U32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326109.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3512"/>
    <dbReference type="MEROPS" id="U32.002"/>
    <dbReference type="EnsemblBacteria" id="ACA87776">
        <property type="protein sequence ID" value="ACA87776"/>
        <property type="gene ID" value="Swoo_3512"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3512"/>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011540_0_2_6"/>
    <dbReference type="OMA" id="YGGVSHF"/>
    <dbReference type="OrthoDB" id="1264653at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032525">
        <property type="entry name" value="Peptidase_U32_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16325">
        <property type="entry name" value="Peptidase_U32_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01276">
        <property type="entry name" value="PEPTIDASE_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_U32_C" evidence="1">
        <location>
            <begin position="357"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="50925" checksum="8824B1E2D0E8D83B" modified="2008-04-29" version="1">MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNDFKMENLATGIQEAHDLGKKLYVVSNIAPHNTKLKTYIKDMAPVVDMNPDAIIMSDPGLIMMAREAFPDQVIHLSVQANAINWASVKFWQQQGIKRVILSRELSLDEIEEIRQRCPDIELEVFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWKYDAHEATETDSGDIIAVQPDVQIQTPTLGAGQPSSDIVLLQEAGRPGEYMPAFEDEHGTYIMNSKDLRAIQHVERLSKMGIDSLKIEGRTKSFYYVARTAQLYRQAIEDAVSGKDFDRTLMHNLEGLAHRGYTEGFLRRHVHDEYQNYDYGYSISDTQQFVGEFTGKRNTIGMAEIDVKNKFSVGDSVEVMTPQGNLTIKVEELFNRKGESVEAGLGSGHFVFLSLPEGVETDKAVLLRNLPQGQDTRNPHAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRR5</accession>
    <name>B1KRR5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="6 8">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glmM</name>
        <name evidence="13" type="ordered locus">Swoo_3566</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="6 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326163.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3566"/>
    <dbReference type="EnsemblBacteria" id="ACA87830">
        <property type="protein sequence ID" value="ACA87830"/>
        <property type="gene ID" value="Swoo_3566"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3566"/>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_7_0_6"/>
    <dbReference type="OMA" id="VDCGNGM"/>
    <dbReference type="OrthoDB" id="1265792at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01554_B">
        <property type="entry name" value="GlmM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="157"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="258"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="373"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="6">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="6">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="445" mass="48015" checksum="75AE2FED38C9EC7F" modified="2008-04-29" version="1">MSMRKFFGTDGIRGKVGAGKMTPELALKLGWAAGRVLSRSGTQKVIIGKDTRISGYLFESAMEAGLSAAGLNVMLMGPMPTPAVAYLTRTFRAEAGVVISASHNPYYDNGIKFFSTDGSKLDDEVELEIERELEKPLTCVESHLLGKVSRIDDAPGRYIEYCKGNFPAEHTLRGLKIVVDCAHGATYHIAPNVFRELGADVIAIGDKPDGLNINHEVGATSMAKICETVVAEKADLGIALDGDGDRIMMVNREGRVIDGDEILYILACDAQLRGVLCGGVVGTLMSNLGLDLALQELDIPFARSNVGDRYVMTMLKEKGWRIGGENSGHILNLDHGTTGDGIVAGILVLAAMCRQNATLDELTANIKMLPQVLVNVRFEGDHDPLASKEVLNAQKEVESQLGERGRVLLRKSGTEPLIRVMVEGDVEADVIKHANYIADAVRNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCY9</accession>
    <name>B1KCY9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-3-methyladenine glycosylase I</fullName>
            <ecNumber evidence="1">3.2.2.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.20" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322664.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0014"/>
    <dbReference type="EnsemblBacteria" id="ACA84315">
        <property type="protein sequence ID" value="ACA84315"/>
        <property type="gene ID" value="Swoo_0014"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0014"/>
    <dbReference type="eggNOG" id="COG2818">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083758_1_0_6"/>
    <dbReference type="OMA" id="YVAYHDT"/>
    <dbReference type="OrthoDB" id="1835478at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004597">
        <property type="entry name" value="Tag"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00624">
        <property type="entry name" value="tag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="194" mass="22131" checksum="EE47B03AEA187DBA" modified="2008-04-29" version="1">MEKQRCSWVGADDLYQAYHDEVWGRPVFDSQELFAKLCLDGQQAGLSWITILKKQHNYEAAFANFDPAIIAKFDDDKVEELLLNKGIVRNRLKVNSIIKNARAYMTHFSDTQGDDFSRFIWSFVGGKPIVNKFNSMSEVPAQTPESEAMSKALKKLGFNFVGPTICYAFMQAVGLVNDHTTDCFYYDLSEKRKS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD01</accession>
    <name>AROE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="1">SDH</shortName>
            <ecNumber evidence="1">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroE</name>
        <name type="ordered locus">Swoo_0047</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322697.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KD01"/>
    <dbReference type="SMR" id="B1KD01"/>
    <dbReference type="STRING" id="392500.Swoo_0047"/>
    <dbReference type="EnsemblBacteria" id="ACA84348">
        <property type="protein sequence ID" value="ACA84348"/>
        <property type="gene ID" value="Swoo_0047"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0047"/>
    <dbReference type="eggNOG" id="COG0169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044063_2_1_6"/>
    <dbReference type="OMA" id="FGNPIKH"/>
    <dbReference type="OrthoDB" id="1054867at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000100140" description="Shikimate dehydrogenase (NADP(+))">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="127"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="150"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <sequence length="273" mass="29381" checksum="A745853E4499AD28" modified="2008-04-29" version="1">MTDRYAVFGNPISHSKSPLIHGIFANETQQVLDYEAILAPKDGFESCLKLFWSQNGKGANVTAPFKEQAFNLCDELSEEAKLAGAVNTLTLLTNGKVRGDNTDGLGLVADLIRNISSLEGKRVLLLGAGGAARGSVLPLLKAGLKVYIHNRTQEKAEKLVEIFTPFGDVKALSIAELIAPFDIIINSTSSSLSGDVPAIPSCVIGVESLCYDMMYSKEMTSFNSWALELGAVKAIDGLGMLVGQAAKSFELWRGVTPEVDTTIKLLREKIKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDA6</accession>
    <name>B1KDA6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326274.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87941">
        <property type="protein sequence ID" value="ACA87941"/>
        <property type="gene ID" value="Swoo_3679"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3679"/>
    <dbReference type="eggNOG" id="ENOG5032XV0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_733401_0_0_6"/>
    <dbReference type="OrthoDB" id="1857505at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="377" mass="42196" checksum="8DF9B5E7CAC1150C" modified="2008-04-29" version="1">MLSLVTVGLIGAGISVETEAKERPSGFYTRGDVSKAPGTRSGYDNPNVADSQKPTNWGKNVDGIVVQLEWASLQPNAPLRAGERAALDTTWIERAIDDIETWNSVPGNNKLGIKLRVFAGIYTPQWVKNEAGSSTLDFKGSSFDGDFPHFWKTAFQTRFKELHHELAAKYDSEPLIKEVSISGCMIKNADMHRARGEYQNMNILIDAGLTWQKDRTCQNWQINAVAGKWDNTWVSVARPHFRQFKKMSSKPSRSDWPLNTSVMQETVETCRKAGSCISGNNSLEQEDKDADAFNNDQHAIYYAASKYRGSSSKAPLYFQTDVKIIQGSGLIHNIIGWGIKNSHVEMIELPTLKAFKKYDDSYLGSSAMQKKRTKLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDG1</accession>
    <name>B1KDG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Biotin/lipoyl attachment domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323309.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0666"/>
    <dbReference type="EnsemblBacteria" id="ACA84962">
        <property type="protein sequence ID" value="ACA84962"/>
        <property type="gene ID" value="Swoo_0666"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0666"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_13_0_6"/>
    <dbReference type="OMA" id="DMEIYEP"/>
    <dbReference type="OrthoDB" id="1174564at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="224"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="441" mass="48621" checksum="660600EF554E2F53" modified="2008-04-29" version="1" precursor="true">MDLNVKKLSSVLMATVFTFTAISFTALQPTNLAWASGDHGHGHEEEEEHVPEGPHGGRLLHNGEFEIEVTMVESGIPPEMRVYAYYKEQAVKPEDIKLELLLNRLGGKTDTVNFTAEGDYLVSTTSIAEPHSFEVEVHAGFKGQSYDWHYDNYTGRTEINDRLLKLSGVKTAQASEQELLFTDTLFGIVAPITDKQFSVTAPYTGVIEQLHVSIGERVEKGQVIATVRNSGTLQSYQVKSPAAGQVTEQLLSLGDSTYNRALVRISDLSSVWIDLSAFPKSIDKLSLGQKVSILDDHSDEVSSSERSNDQYSNQHNSAVASSTISYIAPNMTGGHIARVRAVIENDHGHWRPGMHIQAAIETSSKRVPLAVRVDALQTFMDKPAVFVKHGNTFEVRLLTLGESDGIYTEVLAGLEHNSEYVVENSYLLKADIMKNAAKHVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDI5</accession>
    <name>B1KDI5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinylglutamate desuccinylase/aspartoacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323333.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0691"/>
    <dbReference type="EnsemblBacteria" id="ACA84986">
        <property type="protein sequence ID" value="ACA84986"/>
        <property type="gene ID" value="Swoo_0691"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0691"/>
    <dbReference type="eggNOG" id="COG2988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057850_0_0_6"/>
    <dbReference type="OrthoDB" id="632656at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="302" mass="34011" checksum="ECF9E10FD2B3AAA6" modified="2008-04-29" version="1">MAYINTVKKLPYIYQDITAKNANSLLVVTAAVHGNELVGLKAIDALSNIASKIPLKGRIVVIHGNPEATVQEVRYVDQDFNRAFTATNLISEPTNHELVSAQHLSQLMLNLLDEQASNVAKHLLDIHSMSSTGTPFMSFVADKPPQLIIEQTPIPVIEGIIDSLEGCLAKWFAPYFNSSHIVECGQHQEQSTFDFGFHTLIYHLYLFDMLEDCKQVQQAFDYLSCHTHPYSYLKTNICYRQAVNKDQIFEMQPGFVNLQQVNAGQLLAKISGKKVLAPFDGRVILPCYQRQCEEGYFISQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDT7</accession>
    <name>B1KDT7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_2202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324828.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2202"/>
    <dbReference type="EnsemblBacteria" id="ACA86484">
        <property type="protein sequence ID" value="ACA86484"/>
        <property type="gene ID" value="Swoo_2202"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2202"/>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030246_1_0_6"/>
    <dbReference type="OMA" id="INVSMEP"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="42"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="551" mass="61172" checksum="3D23A58F8F78DBED" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDY2</accession>
    <name>B1KDY2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326316.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3724"/>
    <dbReference type="EnsemblBacteria" id="ACA87984">
        <property type="protein sequence ID" value="ACA87984"/>
        <property type="gene ID" value="Swoo_3724"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3724"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036190_0_0_6"/>
    <dbReference type="OMA" id="YDYAVWD"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007892">
        <property type="entry name" value="CHASE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05228">
        <property type="entry name" value="CHASE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="376"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="526" mass="59304" checksum="664C8D376C9D1535" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEG4</accession>
    <name>B1KEG4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324885.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2261"/>
    <dbReference type="EnsemblBacteria" id="ACA86542">
        <property type="protein sequence ID" value="ACA86542"/>
        <property type="gene ID" value="Swoo_2261"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2261"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_3_6"/>
    <dbReference type="OMA" id="LHQRERF"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022403">
        <property type="entry name" value="Alc_ABC_transptr_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03861">
        <property type="entry name" value="phenyl_ABC_PedC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="11"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="260" mass="29782" checksum="985779513C68A854" modified="2008-04-29" version="1">MMPYYYCLVGIIKREFLRFVQQRTRLLSALIRPLLWLVVFAAGFRAALGVSIMEPYGTYITYQQYITPGLCCMIVLFNGMQSSLSMVYDREMGSMKLLLISPLPRPFLLLCKLIATAILSLIQVCIFLLIAQFVDVDTPVWGYVTAIPAIFLIAFFLGALGLLLSNLIKQLENFAGVMNFVIFPMFFLSSALYPLWKMKEASLWLYWICNYNPFSYCVELLRFALYQELNISAFLVVFLATILVSVLAMFNFAPKRTFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI3</accession>
    <name>B1KEI3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324904.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2280"/>
    <dbReference type="EnsemblBacteria" id="ACA86561">
        <property type="protein sequence ID" value="ACA86561"/>
        <property type="gene ID" value="Swoo_2280"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2280"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_0_6"/>
    <dbReference type="OMA" id="HPCIMAP"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="119"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="5">
        <location>
            <begin position="228"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="526" mass="57163" checksum="4A3583A74CD554AE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN2</accession>
    <name>B1KEN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate-selective porin O and P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326378.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3788"/>
    <dbReference type="EnsemblBacteria" id="ACA88047">
        <property type="protein sequence ID" value="ACA88047"/>
        <property type="gene ID" value="Swoo_3788"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3788"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041653_0_0_6"/>
    <dbReference type="OMA" id="YGELHYN"/>
    <dbReference type="OrthoDB" id="801081at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764348" evidence="2">
        <location>
            <begin position="24"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="395" mass="43377" checksum="38DCD4B7A2C2039B" modified="2008-04-29" version="1" precursor="true">MMMKKTLLATALVGLFASQSAVASDETKELRKIIEQQQKVLQDLERRLEATENRVEKTADVVEEVAESKSATTIGGYGELHYNNITNNDSGEDNKAIDFHRFVLFFGHEFTESTRFFSELEVEHALSGDGKPGEVELEQAYIEHDFNEMFTGKAGLFLVPVGIINETHEPPTFYGVERNPVEKNILPATWWEAGAALNVKAAPGLAFDGAVTSGLEVATEGSKAYNIRSGRQKVAKANASDLAYTARVKYTAVPGLELAATAQYQSDITQGAAGVDTASATMLTAHAIYSIKGFTVKALYAQWDIDGVEAEALGRDDQSGWYIEPSYRFNDSFGLFARYNRYDNEAGSAEDTEITQTNLGVNYWLHENVVFKADYEKVGGAKDADGFNLGVGYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN7</accession>
    <name>B1KEN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent helicase HrpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326383.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3793"/>
    <dbReference type="EnsemblBacteria" id="ACA88052">
        <property type="protein sequence ID" value="ACA88052"/>
        <property type="gene ID" value="Swoo_3793"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3793"/>
    <dbReference type="eggNOG" id="COG1643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_5_6_6"/>
    <dbReference type="OMA" id="DLRILVM"/>
    <dbReference type="OrthoDB" id="604268at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010225">
        <property type="entry name" value="HrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013689">
        <property type="entry name" value="RNA_helicase_ATP-dep_HrpB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08482">
        <property type="entry name" value="HrpB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005496">
        <property type="entry name" value="ATP_hel_hrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01970">
        <property type="entry name" value="DEAH_box_HrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="209"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="842" mass="93240" checksum="0228475B34D56C94" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX0</accession>
    <name>B1KEX0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="3">1.8.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0826</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323468.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0826"/>
    <dbReference type="EnsemblBacteria" id="ACA85121">
        <property type="protein sequence ID" value="ACA85121"/>
        <property type="gene ID" value="Swoo_0826"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0826"/>
    <dbReference type="eggNOG" id="COG0225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_0_6"/>
    <dbReference type="OMA" id="EIHLHTH"/>
    <dbReference type="OrthoDB" id="1554384at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="8"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="170" mass="19636" checksum="F2DB529CA8F0E852" modified="2008-04-29" version="1">MGSEKLGLSGTCYWCTEAIFQSLIGVEAVEQGWISSIGEDDWFSEGVIVTFNPELISLKNLIDIHLHTHSSTRNHSMRDRYRSGVYAIEPQQLTEIADALMVLQSEFTERLITQAYQFNLFKPSADEMQNYYYKDTERPFCQNIITPKLNKLLHTHGDYINKEKLNHSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF09</accession>
    <name>B1KF09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323507.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85160">
        <property type="protein sequence ID" value="ACA85160"/>
        <property type="gene ID" value="Swoo_0866"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0866"/>
    <dbReference type="eggNOG" id="ENOG5031ATI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180091_0_0_6"/>
    <dbReference type="OMA" id="YRSHEAR"/>
    <dbReference type="OrthoDB" id="2033815at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="98" mass="11558" checksum="EA28355CD3449CBD" modified="2008-04-29" version="1">MAMTHHKFRVRRLSASKAVSQEPAEQHKLIHFLLTLVTFGLWGLVWWWLILKSEGKADQLFRGFDDAYWSYLIEREQPPAALHKMKVDAELKRGYFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF49</accession>
    <name>B1KF49_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2311</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324932.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2311"/>
    <dbReference type="EnsemblBacteria" id="ACA86590">
        <property type="protein sequence ID" value="ACA86590"/>
        <property type="gene ID" value="Swoo_2311"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2311"/>
    <dbReference type="eggNOG" id="COG0539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015805_2_1_6"/>
    <dbReference type="OMA" id="SLNEFRY"/>
    <dbReference type="OrthoDB" id="1235756at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000110">
        <property type="entry name" value="Ribosomal_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002111">
        <property type="entry name" value="RpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00717">
        <property type="entry name" value="rpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="105"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="192"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="277"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="364"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="451"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="555" mass="61116" checksum="DDE8FAFA77201384" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFA9</accession>
    <name>B1KFA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324992.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2371"/>
    <dbReference type="EnsemblBacteria" id="ACA86650">
        <property type="protein sequence ID" value="ACA86650"/>
        <property type="gene ID" value="Swoo_2371"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2371"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_495111_0_0_6"/>
    <dbReference type="OMA" id="YHAIYPA"/>
    <dbReference type="OrthoDB" id="1786311at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="550" mass="61148" checksum="1E39DE4B863C7DAB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFB2</accession>
    <name>B1KFB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324995.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2374"/>
    <dbReference type="EnsemblBacteria" id="ACA86653">
        <property type="protein sequence ID" value="ACA86653"/>
        <property type="gene ID" value="Swoo_2374"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2374"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_1_6"/>
    <dbReference type="OMA" id="GWWVLAP"/>
    <dbReference type="OrthoDB" id="1497607at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="44"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="22108" checksum="4628971C922BD6A1" modified="2008-04-29" version="1">MNISDSARLTYDFMTANDAQLLFELDQDSEVMRHINGGELTSMQEIREIFIPRLESYADISKGWGMWKVSIKPNSNSAEQLSASEQFLGWILVRPLEFFSESPQWNNLELGWRFKQLAWGKGIATEAAQAVMEVVTNSEHVQYISAIALEENISSIKIMEKLGMKFLKKAMHHDPLGDCELVYYQKEIKPQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE9</accession>
    <name>B1KFE9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326454.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3866"/>
    <dbReference type="EnsemblBacteria" id="ACA88124">
        <property type="protein sequence ID" value="ACA88124"/>
        <property type="gene ID" value="Swoo_3866"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3866"/>
    <dbReference type="eggNOG" id="COG5373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_288188_0_0_6"/>
    <dbReference type="OMA" id="IMLHFEL"/>
    <dbReference type="OrthoDB" id="109796at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019286">
        <property type="entry name" value="DUF2339_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38434">
        <property type="entry name" value="PTHR38434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10101">
        <property type="entry name" value="DUF2339"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="590"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="646"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="678"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="705"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="753"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="783"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="809"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="841"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="871"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="902"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="931"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="962"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1013" mass="112458" checksum="18D00C5EA36422A6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFU8</accession>
    <name>B1KFU8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sensor protein</fullName>
            <ecNumber evidence="14">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">Swoo_0971</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323611.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0971"/>
    <dbReference type="EnsemblBacteria" id="ACA85264">
        <property type="protein sequence ID" value="ACA85264"/>
        <property type="gene ID" value="Swoo_0971"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0971"/>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_10_6"/>
    <dbReference type="OMA" id="FRAESEW"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029095">
        <property type="entry name" value="NarX-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042295">
        <property type="entry name" value="NarX-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016380">
        <property type="entry name" value="Sig_transdc_His_kin_NarX/NarQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13675">
        <property type="entry name" value="PilJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003167">
        <property type="entry name" value="STHK_NarX/NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 14 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12 14" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="18">
        <location>
            <begin position="173"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="17">
        <location>
            <begin position="366"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR003167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACA85264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="567" mass="63653" checksum="10BA8E6D1C31FA4E" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFX3</accession>
    <name>B1KFX3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325022.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2402"/>
    <dbReference type="EnsemblBacteria" id="ACA86680">
        <property type="protein sequence ID" value="ACA86680"/>
        <property type="gene ID" value="Swoo_2402"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2402"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_6"/>
    <dbReference type="OMA" id="VYLCCKA"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="278" mass="29567" checksum="BDF09EC6DB08A1C5" modified="2008-04-29" version="1" precursor="true">MKLSNAKGKLAVITGGSSGLGYAIAKELASKGFDLLLVARNEAQLKEASSKLIADSGVKVHTTSVDVSKEEDVLSLKETVRSLAPCADIIVNSAGIVSGGFLVDTPLAEWDRLYNVNVRGLVSVLKSLLPDMIEQGGSDGQERHIVNIASAAAYTATGGMSAYGSTKAGVLALSESLAHEVAPSHVGVTTVCPEFVKTPIGSKVMLFGRMDNARSKRIIEKMFDRSTITTDELAVKVLKAITSGKLVVPAGKQATIAYHFKRVMPVRFFKMIDKALRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY5</accession>
    <name>B1KFY5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325034.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2414"/>
    <dbReference type="EnsemblBacteria" id="ACA86692">
        <property type="protein sequence ID" value="ACA86692"/>
        <property type="gene ID" value="Swoo_2414"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2414"/>
    <dbReference type="eggNOG" id="ENOG502Z8T7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106580_0_0_6"/>
    <dbReference type="OMA" id="EYMFTYS"/>
    <dbReference type="OrthoDB" id="1484915at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021370">
        <property type="entry name" value="DUF2987"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11205">
        <property type="entry name" value="DUF2987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767032" evidence="1">
        <location>
            <begin position="20"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="207" mass="23212" checksum="CFF1C60D2E6D8251" modified="2008-04-29" version="1" precursor="true">MKKSLLFSCLIVACSSVQAAPISLEYQGFYQRLKQVNKGHYPLVELAFFVPGKDKCHIESGTISTEKESFPLTITKDQRLFLPFDDKLKSDRALINLNIKGQAENCNISMQVRAKQTKLNYAQSELLEIQAQMDALLDEMQGFPMRHFSSDIAGINFVFEPDSKVSVKIDGVEQLVTGSLQLSREQISQLKALELASKPKVISPRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGB7</accession>
    <name>B1KGB7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326583.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3997"/>
    <dbReference type="EnsemblBacteria" id="ACA88254">
        <property type="protein sequence ID" value="ACA88254"/>
        <property type="gene ID" value="Swoo_3997"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3997"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_87_4_6"/>
    <dbReference type="OMA" id="QQAAWIP"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="160"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="261" mass="29451" checksum="03CC7E62ACD4F5DF" modified="2008-04-29" version="1">MPKMIELTPSNESMKPLSRPIVVVNRELFIHSTVKKHRHTWGQFVYASRGVLAVATTVSRYIVPPEQGVWVTPNTCHEVTAISDVELTSFYFDNTVLSGFPECCCVLNVEFFLKVLIVESKSIDGDYEWSGVDGRLLRLIRDKLIVAIKIPLQLPYPKDSRLLAILTQLQLEPSNRNNLVQWGNIVGASARTLSRLFKNETGLTYSEWRQRFNVQVAITKLSSGETVSNISLNLGYESPSSFIYMFRKLTGVTPGFYSQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGI8</accession>
    <name>B1KGI8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323663.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1023"/>
    <dbReference type="EnsemblBacteria" id="ACA85316">
        <property type="protein sequence ID" value="ACA85316"/>
        <property type="gene ID" value="Swoo_1023"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1023"/>
    <dbReference type="eggNOG" id="ENOG5032S89">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143375_0_0_6"/>
    <dbReference type="OMA" id="LHVAGWV"/>
    <dbReference type="OrthoDB" id="2002615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011223">
        <property type="entry name" value="UCP028770"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11742">
        <property type="entry name" value="DUF3302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028770">
        <property type="entry name" value="UCP028770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="132" mass="15305" checksum="C1BA5834C164055B" modified="2008-04-29" version="1">MFLDYFALGVIFFVAIFLFYGVIVIHDIPYEIAKKRNHPQQDALHVAGWVSLFTLHAIWPFLWIWATLYREDRGWGFNAVVERELALEDEVKQLNETVAKLELRLQSVELNGQPTQSEPVISDVQSSNKEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGJ8</accession>
    <name>B1KGJ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1033</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323673.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1033"/>
    <dbReference type="EnsemblBacteria" id="ACA85326">
        <property type="protein sequence ID" value="ACA85326"/>
        <property type="gene ID" value="Swoo_1033"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1033"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_8_0_6"/>
    <dbReference type="OMA" id="AAMDCYD"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="135"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="238"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="391" mass="43417" checksum="11FC7E0ADD4FC3D1" modified="2008-04-29" version="1">MARVHFDWTDPLQLNALLSDEERMIRDSVYDYAQDKLMSRVLMANREEHFDREIMNELGEMGLLGATLPEKYGCSNVNYVSYGLVAREIERVDSGYRSAMSVQSSLVMYPIYAYGSEEQRVKYLPKLATGEWVGCFGLTEPDVGSDPGGMKTRAERIDGGYRLNGAKMWITNSPIADVFIVWAKLEGKIRGFILEKGMKGLSAPKIEGKFSLRASVTGEIVMDNVEVPESALMPNAEGLQGPFGCLNKARYGIAWGALGAAEFCWHGARQYTLDRVQFNRPLAANQLIQKKLADMQTEITTGLFACLQAGRLMDQEALPVEAISLIKRNSCGKALDIARMSRDMHGGNGISDEFHIIRHVMNLEAVNTYEGTHDIHALILGRAQTGIQAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM2</accession>
    <name>B1KGM2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MEMO1 family protein Swoo_1057</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the MEMO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323696.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1057"/>
    <dbReference type="EnsemblBacteria" id="ACA85350">
        <property type="protein sequence ID" value="ACA85350"/>
        <property type="gene ID" value="Swoo_1057"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1057"/>
    <dbReference type="eggNOG" id="COG1355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038085_2_0_6"/>
    <dbReference type="OMA" id="EQEAQYG"/>
    <dbReference type="OrthoDB" id="1070303at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PTHR11060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="268" mass="29465" checksum="C2226EEC25277EC1" modified="2008-04-29" version="1">MTSLTRQAAVAGRFYPAEPTALKQMINTYLGRCASLTNDPKLKSSPTKVIIVPHAGYIYSGQVAASAFALLAPRRKQIKRVVLLGPAHRVHLKGCALPSSESFETPLGQQVIDKVALRQLSEHSKILISDLPHNEEHSLEVELPFLQLCLDKFELIPILVGDISPHAMASILEQVWGGDETLIVVSSDLSHYHSYQEAAELDRETCRQIINHNSALTPEQACGSRALNAIAIQAEYHKLQTHQLSYQNSGDTSGNRSRVVGYASFALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGY4</accession>
    <name>B1KGY4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326625.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4040"/>
    <dbReference type="EnsemblBacteria" id="ACA88296">
        <property type="protein sequence ID" value="ACA88296"/>
        <property type="gene ID" value="Swoo_4040"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4040"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_1_6"/>
    <dbReference type="OMA" id="PYIYTPV"/>
    <dbReference type="OrthoDB" id="538961at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="1">
        <location>
            <begin position="9"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="357" mass="39666" checksum="4C79DA62508AFC4C" modified="2008-04-29" version="1">MHKKIDNQTVNIGVLLPFSGPIGLWGNSCEACSILAAAELNSYRGILDCKVELEFIDASLKPSNVVKEVSAKVNSGQLSALVGTHTSDVRKEVANAIKGKVPYIYTPMYEGGDQGTGMYLTGLTTEQSVLPTLDWLCSNVTSQRWFFVGSDYIWPAKTHSSAIDFLYSRHREVVANELLPLKCKDFSSTLERIEQSKPDVVFINLLGEGAIDFNRQFAQRGLDSQIIRYCGAIEENMLYAVGSENSRNLFSSMGYFEGLKTNEAQNFNKLYYNNFGDLAPGLNQISVSSYEGIMLLADLAQRSQSLQTHDIEKTSMSAVNFHSPRGEITLLNKNVQADVFIVQAKDNRFVPLHRIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH01</accession>
    <name>B1KH01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326642.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4057"/>
    <dbReference type="EnsemblBacteria" id="ACA88313">
        <property type="protein sequence ID" value="ACA88313"/>
        <property type="gene ID" value="Swoo_4057"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4057"/>
    <dbReference type="eggNOG" id="COG0727">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151365_0_0_6"/>
    <dbReference type="OMA" id="DGWCAAL"/>
    <dbReference type="OrthoDB" id="1677662at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="11119" checksum="5F573D241C217C34" modified="2008-04-29" version="1">MTIDVTNLNEPEITCATCQACCCRLQVLIISDTGVPDEHIEEAEWGGEVMRRLDDGWCSALDRETKMCTIYEQRPWICREFEMGSYECKTERTDNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH09</accession>
    <name>B1KH09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326650.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88321">
        <property type="protein sequence ID" value="ACA88321"/>
        <property type="gene ID" value="Swoo_4065"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4065"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_9_6"/>
    <dbReference type="OMA" id="FVSQGFY"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="21655" checksum="E15A582953C9D082" modified="2008-04-29" version="1">MSKPDKKQAILDTALTLFVSQGFYATSTASIAKKAGVATGTLFHHFPSKDELMNHLFISIKQEFADAILTSVTDSGNLKQDAQHLWYAAIQWAIENPLKQEFFQQYSMSPSIPLEIREQAMNSILSFMGALMQKGHALGLLADYPLSLMQDNCHGQFLAATRYFLDNPGKWQEPTHKEASFAMFWNAMRTDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHK3</accession>
    <name>B1KHK3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="7">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glyoxalase II</fullName>
            <shortName evidence="7">Glx II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gloB</name>
        <name evidence="9" type="ordered locus">Swoo_2611</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a beta-lactam + H2O = a substituted beta-amino acid</text>
            <dbReference type="Rhea" id="RHEA:20401"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35627"/>
            <dbReference type="ChEBI" id="CHEBI:140347"/>
            <dbReference type="EC" id="3.5.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325228.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2611"/>
    <dbReference type="EnsemblBacteria" id="ACA86888">
        <property type="protein sequence ID" value="ACA86888"/>
        <property type="gene ID" value="Swoo_2611"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2611"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_4_1_6"/>
    <dbReference type="OMA" id="NYIWLLQ"/>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017001">
        <property type="term" value="P:antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001018">
        <property type="entry name" value="Beta-lactamase_class-B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00743">
        <property type="entry name" value="BETA_LACTAMASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="8">
        <location>
            <begin position="17"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="263" mass="29563" checksum="5DEFAA50940260E3" modified="2008-04-29" version="1">MPSETDLTITPIQAFNDNYIWVISKSSSPLVYVVDPGDANVVIHYLETNQLTLAGILITHHHSDHTGGIKSLIEYSATDLEIYGPSSENIADINNPISTQPHIKLQALELTARVYQLPGHTLGHIAYHIQDELFCGDTLFSGGCGRLFEGTASQLHHSLELLASLEQHTRVYCAHEYTLSNLKFAIRVEPNNSQLAHYYQDCQTLRANKKITLPSTIKTEKEINPFLRCHIHEIVNAVNQHFNQKPVDTVTTFGLLRQWKDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHL1</accession>
    <name>B1KHL1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
            <ecNumber evidence="5">1.8.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">msrP</name>
        <name evidence="7" type="ordered locus">Swoo_2619</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51296"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51292"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="5">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Periplasm</location>
        </subcellularLocation>
        <text evidence="5">Is attached to the inner membrane when interacting with the MsrQ subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MsrP family.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325236.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2619"/>
    <dbReference type="EnsemblBacteria" id="ACA86896">
        <property type="protein sequence ID" value="ACA86896"/>
        <property type="gene ID" value="Swoo_2619"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2619"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045520_0_0_6"/>
    <dbReference type="OMA" id="WPYTEGL"/>
    <dbReference type="OrthoDB" id="1729032at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016672">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01206">
        <property type="entry name" value="MsrP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022867">
        <property type="entry name" value="MsrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="6">
        <location>
            <begin position="113"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="95"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="253"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="338" mass="37871" checksum="3A9B9DB5630ED4CD" modified="2008-04-29" version="1" precursor="true">MHFIKRPSWDTVKSSDITPESVFNDRRNIIKALGLGAIGASIPGQVQAGIFDLFGKSQPSTPFITSPLAFTVNKGFESSEAKTPFSKVSTHNNFYEFGTSKSDPVENAQGFKVDPWSLVIDGEVDNPITLGFEDLTKMMALEERTYRLRCVEAWSMVVPWVGFPLAALLKKAGVNSRAKYVAFETLFDPDQMPGQKSRLMGGGIHYPYVEGLTLAEAMNDLSFLAVGLYGKSLPPQNGAPIRLVVPWKYGFKSIKSLVRIRVMDKRPPTSWNQLAPQEYGFYANVNPDVDHPRWSQATERRIGEGGLFSATRIKTRPFNGYQEQVADLYRDLDLRRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHY5</accession>
    <name>B1KHY5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Replicative DNA helicase</fullName>
            <ecNumber evidence="4 13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_4207</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 13"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326792.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4207"/>
    <dbReference type="EnsemblBacteria" id="ACA88463">
        <property type="protein sequence ID" value="ACA88463"/>
        <property type="gene ID" value="Swoo_4207"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4207"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005373_0_0_6"/>
    <dbReference type="OMA" id="IEFHARI"/>
    <dbReference type="OrthoDB" id="1709134at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="12 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="14">
        <location>
            <begin position="197"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA88463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="468" mass="51558" checksum="DA5D6812D865C693" modified="2008-04-29" version="1">MSQQGAFKAKKKPRDIQMDALKMPPHSLEAEQSVLGGLMLDSDAWDRVAEAVVAEDFYSRSHRMIFNAMEALIAAGQPLDLITVSEQLEVEDQLEEAGGFAYLGEIAKNTPSAGNILSYGDIVRERAVVRDMIKVANEIADAGFNPEGRNSSELLDLAETKVFKIAESRANANEGPEGIKVILEKTVDKIEALYNNPTGGVTGVSSGFGDLDKMTAGFQSGDLIIVAARPSMGKTTFAMNLCEAAALNEDKPVLIFSLEMPSEQIMMRMLASLGRVDQTKIRTGQLDDDDWARVSSTMGIMLEQGKMYIDDGSGLTPTEVRSRARRIAREHGGLSMIMIDYLQLMQVPALKDNRTLEISEISRSLKALAKELEIPVIALSQLNRSLEQRADKRPVNSDLRESGAIEQDADLIMFIYRDEVYNDDSEHKGVAEIIIGKQRNGPIGRVPLTFQGQFSRFDNYAGPQFEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI20</accession>
    <name>B1KI20_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323844.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1205"/>
    <dbReference type="EnsemblBacteria" id="ACA85498">
        <property type="protein sequence ID" value="ACA85498"/>
        <property type="gene ID" value="Swoo_1205"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1205"/>
    <dbReference type="eggNOG" id="ENOG5031V4J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126055_1_0_6"/>
    <dbReference type="OMA" id="DCVPVWP"/>
    <dbReference type="OrthoDB" id="1952072at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021284">
        <property type="entry name" value="DUF2750"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11042">
        <property type="entry name" value="DUF2750"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="125" mass="14454" checksum="4E17B099F55C4362" modified="2008-04-29" version="1">MSKSAKDASQMTPEARYDYFVEQAKEHKTLWTLQDNDGCVMLTTDDEDCIPMWPSEEAANSWAVDDWKDCTALSIPLDEWLERWVPGMQDDDLFVAVYPVQDDLGVVIEPYDVEQRLAPKKQQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI49</accession>
    <name>B1KI49_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323873.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1235"/>
    <dbReference type="EnsemblBacteria" id="ACA85527">
        <property type="protein sequence ID" value="ACA85527"/>
        <property type="gene ID" value="Swoo_1235"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1235"/>
    <dbReference type="eggNOG" id="ENOG50318V5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1804886_0_0_6"/>
    <dbReference type="OMA" id="PLWADMF"/>
    <dbReference type="OrthoDB" id="1871421at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="16030" checksum="C6C3B3AC4A63BA8D" modified="2008-04-29" version="1">MEETQHSFNLTSSFDQRFSLVVFASLCLTSFLAWPLLDSLLYHLIKALFFSIMLLFFIHQFLQLKSWRFQFVLNGAGEGRLQGEERFKLTQKAFVSPFVCLFYIEADEKQTLMIVWSDMCDDTSYRNLCRLLLASKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI96</accession>
    <name>B1KI96_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325287.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2671"/>
    <dbReference type="EnsemblBacteria" id="ACA86947">
        <property type="protein sequence ID" value="ACA86947"/>
        <property type="gene ID" value="Swoo_2671"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2671"/>
    <dbReference type="eggNOG" id="ENOG502ZUB0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129314_0_0_6"/>
    <dbReference type="OMA" id="APLANDM"/>
    <dbReference type="OrthoDB" id="2099956at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15165" checksum="1B5E6A4380494163" modified="2008-04-29" version="1" precursor="true">MHSNMTLVILLVVFLCQVLTLGEAFSVQYPHSYHPIGPAVSHHHLHGSSATQGHHHGPSLSEYTESVILFDGEVESAVGDHEHANHSHMPSHPPVESQLTCCFFLYGTLSHDDLTYLNIGYAPPLPPPFYSSFYSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE0</accession>
    <name>B1KIE0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Phosphoenolpyruvate synthase</fullName>
            <shortName evidence="10">PEP synthase</shortName>
            <ecNumber evidence="6 10">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2715</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="6 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325328.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2715"/>
    <dbReference type="EnsemblBacteria" id="ACA86991">
        <property type="protein sequence ID" value="ACA86991"/>
        <property type="gene ID" value="Swoo_2715"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2715"/>
    <dbReference type="eggNOG" id="COG0574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_6_2_6"/>
    <dbReference type="OMA" id="RRFVQMY"/>
    <dbReference type="OrthoDB" id="997616at2"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000854">
        <property type="entry name" value="PEP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01418">
        <property type="entry name" value="PEP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="17"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="383"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="481"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA86991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="789" mass="87029" checksum="CE22C39DD1815FD4" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE3</accession>
    <name>B1KIE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitin-binding domain 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2718</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325331.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2718"/>
    <dbReference type="CAZy" id="AA10">
        <property type="family name" value="Auxiliary Activities 10"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86994">
        <property type="protein sequence ID" value="ACA86994"/>
        <property type="gene ID" value="Swoo_2718"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2718"/>
    <dbReference type="eggNOG" id="COG3397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039396_2_1_6"/>
    <dbReference type="OMA" id="HYIVYRE"/>
    <dbReference type="OrthoDB" id="1005693at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041029">
        <property type="entry name" value="GbpA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18416">
        <property type="entry name" value="GbpA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-3" evidence="3">
        <location>
            <begin position="356"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="405" mass="45097" checksum="940CFA295E5D8732" modified="2008-04-29" version="1" precursor="true">MSFSNFINIEKFMKQITCLSSLLGVLLISSVLTQELHAHGYMDSPKARQQFCVDDGGYWWPDDGSAIPNLACRAAFLETGTKQLVQNNEFSENVVDYHNLAAVKQAIPNGQLCAGGDSEKSGMDTPSMHWQRTDVTPDNNGQVSIIFDAHTPHNPSFWEFYLSDETFDVANEVLSWEKLELITQVGNVGVSEVNGKKVYQIMISLPLGRVGPATLYTRWQREDAAGEGFYNCSDINIINDSQPQEWVVLEQYIANGLTANKGDEVWFRLFSAQGDELVFDKLQVTAANLQTELWARQLAESVMSQHGELVQVGVKGAGGELVYSDDLALNKVWSKQLGITFRLDVKTISEPPSCQLMPWDVATVYNTGGEVVYDSIRYQAQWWTKGDVPSSSGEWGVWKNLGPCL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIH9</accession>
    <name>PURA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenylosuccinate synthetase</fullName>
            <shortName evidence="1">AMPSase</shortName>
            <shortName evidence="1">AdSS</shortName>
            <ecNumber evidence="1">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">purA</name>
        <name type="ordered locus">Swoo_4219</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326803.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIH9"/>
    <dbReference type="SMR" id="B1KIH9"/>
    <dbReference type="STRING" id="392500.Swoo_4219"/>
    <dbReference type="PRIDE" id="B1KIH9"/>
    <dbReference type="EnsemblBacteria" id="ACA88475">
        <property type="protein sequence ID" value="ACA88475"/>
        <property type="gene ID" value="Swoo_4219"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4219"/>
    <dbReference type="eggNOG" id="COG0104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029848_0_0_6"/>
    <dbReference type="OMA" id="FHHAKPI"/>
    <dbReference type="OrthoDB" id="232152at2"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000089340" description="Adenylosuccinate synthetase">
        <location>
            <begin position="1"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="13"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="39"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="41"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="300"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="332"/>
            <end position="334"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="415"/>
            <end position="417"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <sequence length="431" mass="46882" checksum="B8FEFA2E4AA27D7D" modified="2008-04-29" version="1">MGKNVVVLGTQWGDEGKGKIVDLLTEQSKYVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRDNVKCIIGNGVVLAPDALMTEIKMLKERGVPVEERLLISEACPLILPFHCALDIAREKARGNNAIGTTGRGIGPAYEDKVSRRGLRVGDLFDAELFAEKLKEVMAYHNFMLTEYYKCEAVDYEETLKDALAIADYLKSMCVDVTELLDQARKAGEPILFEGAQGTLLDIDHGTYPFVTSSNTTAGGVATGSGFGPRHLDYVLGIMKAYTTRVGAGPFPTELQCEIGDHLGTKGHEFGATTGRKRRPGWLDVVAMKRAVQINSISGFCLTKLDVLDGLEEVKICVGYQYPDGSVATVTPLAAEGYEQVTPVLETMPGWSENTFGATSVEQLPQAALNYIKRLEELLDTPIDIISTGPDRNETMILVNPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ8</accession>
    <name>B1KIQ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326881.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88554">
        <property type="protein sequence ID" value="ACA88554"/>
        <property type="gene ID" value="Swoo_4299"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4299"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053827_0_0_6"/>
    <dbReference type="OMA" id="SINICAY"/>
    <dbReference type="OrthoDB" id="1547701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="37571" checksum="438E3ED838BEEB10" modified="2008-04-29" version="1">MPRPRRTQMSIEDTSWYHCCSRVARRAFLFGNDELTGKNYDYRRAWVESLLLKLGDIFAIDVAAYAVMSNHLHLVLQIDIELANRWTDREVVEQWHQLFNGTELTQRFAKGEVIEEYQVAKLKHLVAIYRSRLCDISWFMRCLNEPIARMANKEDKCTGRFWEGRFKSQALLDEAAVLACMAYVELNPIRAQMADTLESSDHTSIQLRVNAALKGEQSTQLLPFIGDERLNQPKGINFALKDYLELVDETGRIIRNDKRGSISANSTKILTQLNISSDNWIKLTSEFGELFHGPVGNTQELTSFCEHLQKRRRHFAKCCKYLEDG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIR6</accession>
    <name>CH60_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chaperonin GroEL</fullName>
            <ecNumber evidence="1">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Chaperonin-60</fullName>
            <shortName evidence="1">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">groEL</name>
        <name evidence="1" type="synonym">groL</name>
        <name type="ordered locus">Swoo_4308</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + a folded polypeptide = ADP + phosphate + an unfolded polypeptide.</text>
            <dbReference type="EC" id="5.6.1.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326889.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIR6"/>
    <dbReference type="SMR" id="B1KIR6"/>
    <dbReference type="STRING" id="392500.Swoo_4308"/>
    <dbReference type="PRIDE" id="B1KIR6"/>
    <dbReference type="EnsemblBacteria" id="ACA88562">
        <property type="protein sequence ID" value="ACA88562"/>
        <property type="gene ID" value="Swoo_4308"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4308"/>
    <dbReference type="eggNOG" id="COG0459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016503_3_0_6"/>
    <dbReference type="OMA" id="TDTDKME"/>
    <dbReference type="OrthoDB" id="265347at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000130059" description="Chaperonin GroEL">
        <location>
            <begin position="1"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="87"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <sequence length="550" mass="57392" checksum="38F6F975046B7E8A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV0</accession>
    <name>B1KIV0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323944.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1306"/>
    <dbReference type="EnsemblBacteria" id="ACA85598">
        <property type="protein sequence ID" value="ACA85598"/>
        <property type="gene ID" value="Swoo_1306"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1306"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022247_0_0_6"/>
    <dbReference type="OMA" id="HHLFDYP"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033856">
        <property type="entry name" value="Trp_halogen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011396">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR011396-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="507" mass="56974" checksum="ED33AE65A67EF17F" modified="2008-04-29" version="1" precursor="true">MKIKRIAIVGAGTAGWLAANHLGSELSADQDVEITVIESKDVPTIGVGEGTVPYIMNSLKRFGISEAELLYSCDTTFKQGIKFVNWLDSGSRGDNFYYHPFDVPYPSGFDVSPYWVAHGGKRPFDDVGIQARICELGLAPKRKSSGEYEGALTYAYHFNALKFAQLLAKNAQKRFNVTHQFATVVGAKKAENGDITHLITKDDTELVFDFYVDCSGFSSILIDKELKVPFVSKADELLTDSVLVQQVPLKDEDELPPYTTATAHSAGWIWDIPLTTRRGTGFVYSSRHMSDEQALSEYADYLGVEQGTISPRKLPMEIGYREAFWSQNCVALGLAQGFVEPLEATSILVTDFSAELLARNFPRNTSDIEALIPHYNKVVTYVWERVVDFIKLHYCISDREDSQFWLDNRKEDTFSDELKQRLTKFKVSTPKQSDFFSKFDLFNDKNFLYVLYGMEFKTKAISISAKEIEHCSMLLQSNDNLVKTAADELLSHKSWLLGLKAAMSPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIY5</accession>
    <name>B1KIY5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323979.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1341"/>
    <dbReference type="EnsemblBacteria" id="ACA85633">
        <property type="protein sequence ID" value="ACA85633"/>
        <property type="gene ID" value="Swoo_1341"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1341"/>
    <dbReference type="eggNOG" id="COG3803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1748387_0_0_6"/>
    <dbReference type="OMA" id="QRRCFYD"/>
    <dbReference type="OrthoDB" id="1756289at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="150" mass="17152" checksum="97D45284F5CF3DEB" modified="2008-04-29" version="1">MEQFITQWFSEYNKGEGVIRSSLSNQTQSHWEALLTDAKQGKLNDWQKTPPGRMSLILLLGPVAHLLADSDVTELNRRARDLCIQGVDLGFDTQLDLVQRRCFYDPLFYSSVAKDRELLLRLLEGMQSQAELPEKTVWSNWYAQASSLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIZ2</accession>
    <name>B1KIZ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323986.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1348"/>
    <dbReference type="EnsemblBacteria" id="ACA85640">
        <property type="protein sequence ID" value="ACA85640"/>
        <property type="gene ID" value="Swoo_1348"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1348"/>
    <dbReference type="eggNOG" id="ENOG5032QYJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087606_0_0_6"/>
    <dbReference type="OMA" id="AKMITQG"/>
    <dbReference type="OrthoDB" id="1997756at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767106" evidence="1">
        <location>
            <begin position="21"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="258" mass="29409" checksum="3A4E1D5EAC612EC8" modified="2008-04-29" version="1" precursor="true">MKYSLLSTALLFTVSLNCFAHSEGIEEAVSKKKVSRFQCDQLAPTNIKLEYDVIESDRFGTPQASYLMRLIKNQHQVIYQTSPQTFEAWDKNGEYIRYFPEERRSITYRPSDLRSLNISYDLLQQFHLVSPELKSQLQRGENTQASCFRLEQYSGLQGEQNIKLKWIESLALPYQFSITHARGSVHYQLRDASPMTSEKVNTITQGYNDLDFADVGDSESDPFIAKMITQGFIQHGSSGFYDTDGNSLSGGDHHGHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ83</accession>
    <name>B1KJ83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2828</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325439.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2828"/>
    <dbReference type="EnsemblBacteria" id="ACA87103">
        <property type="protein sequence ID" value="ACA87103"/>
        <property type="gene ID" value="Swoo_2828"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2828"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_688662_0_0_6"/>
    <dbReference type="OMA" id="EPANSTI"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="277"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="400" mass="45456" checksum="D9F139F8BBC5F526" modified="2008-04-29" version="1">MRLALLNFVDSYSLLAKGYGKVTYINLLSLRYPKDPERELNYLERVHRFFSYSISNMLGLIFGASLISVILYYYGAMIGQIQLLFACTAVVATCVYLISRYVDKHKLEGELLANLLISRVTLGCVIGVLYGVAVFLLPKPIEEASVLFLLCIYLASIAVAIFQYSVIPTYYILFNFSMLIPVMFYFVIFPSTFGYLMILVLISGSLMFISKGFKISKNEIHSITVNLRLQAEVAEHVLTRQKLQEMALYDNLTKVANRHLFEESAENSLERAKEQKQSMALLYIDLNNFKTINDRFGHEVGDKVLIEAANRVKTKIRHTDLVARFGGDEFVVVLENYNLDVVRVDLIDVIRGVLNEDILIEGQLLELRASIGVSIFPNDGSSLRDLLHNADTHMYNQKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJE6</accession>
    <name>B1KJE6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326944.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4365"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88618">
        <property type="protein sequence ID" value="ACA88618"/>
        <property type="gene ID" value="Swoo_4365"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4365"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_9_3_6"/>
    <dbReference type="OMA" id="PTIGNHK"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="22"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_3_C" evidence="4">
        <location>
            <begin position="377"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="608" mass="66522" checksum="A998BF6D3C708FBA" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJY9</accession>
    <name>B1KJY9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase S49 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2903</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S49 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325512.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2903"/>
    <dbReference type="EnsemblBacteria" id="ACA87176">
        <property type="protein sequence ID" value="ACA87176"/>
        <property type="gene ID" value="Swoo_2903"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2903"/>
    <dbReference type="eggNOG" id="COG0616">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070316_0_0_6"/>
    <dbReference type="OMA" id="FLYEYGL"/>
    <dbReference type="OrthoDB" id="1318587at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013703">
        <property type="entry name" value="Peptidase_S49_N_proteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08496">
        <property type="entry name" value="Peptidase_S49_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="8">
        <location>
            <begin position="156"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="44"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA87176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="38091" checksum="A5DE4A2888473C1A" modified="2008-04-29" version="1">MEFLYEYGMFFAKAITVVLSIIAVVIVILASAVKQKGGKGELRLTNISEELKELQHDLKEELYTKQQFKAYEKQLKADEKAKEKALKEQKEPVSEPRVFVVDFKGSIDANEVSSLREEISAIIAIAEPGDEAIVNVESGGGMVHGYGLASSQLDRLRQANIHLTICVDKVAASGGYMMACVANKVYAAPFAIVGSIGVVAQVPNFNKLLKKHDIDYEQHTAGDFKRTLTVFGENTDEGREKFQQELEETHELFKGFISQYRPELELAKVATGEHWYGQQAIELGLIDAIATSDDVVMNLAKERTVIRVKYQLKKKFADKLAHAASLSVSSVFNKMAEKNQPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ3</accession>
    <name>B1KJZ3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2907</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325516.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2907"/>
    <dbReference type="EnsemblBacteria" id="ACA87180">
        <property type="protein sequence ID" value="ACA87180"/>
        <property type="gene ID" value="Swoo_2907"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2907"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_1_1_6"/>
    <dbReference type="OMA" id="SMEFAPF"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="3"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="287" mass="32390" checksum="FCFD3E3DA03652EF" modified="2008-04-29" version="1">MSEKLQKVLARAGHGSRREMEAWIAAGRISIDGEIANLGDRVEADVKIRIDGRAVSIKSEEDLVCRVIAYHKPEGEICSRKDPEGRPTVFDRLPKTRDSRWVAVGRLDINTSGLLLFTSDGELANRLMHPSNEVEREYAVRTFGEVTDACIQRLRTGVTLEDGPAHFDKVKAAGGEGMNKWWHVSLAEGRNREVRRLWESQEVQVSRLIRIRYGMIELPKSLPRGGWVELELEQVNYLRQTAGLAIENRTLLGTDKHSVARAKVKSAKIKRAVNKHKVNAAKNTRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK09</accession>
    <name>B1KK09_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2923</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325532.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2923"/>
    <dbReference type="EnsemblBacteria" id="ACA87196">
        <property type="protein sequence ID" value="ACA87196"/>
        <property type="gene ID" value="Swoo_2923"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2923"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023103_0_0_6"/>
    <dbReference type="OrthoDB" id="1123871at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="711" mass="81255" checksum="B0BEF578A117B6A5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK69</accession>
    <name>B1KK69_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4448</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4448"/>
    <dbReference type="EnsemblBacteria" id="ACA88700">
        <property type="protein sequence ID" value="ACA88700"/>
        <property type="gene ID" value="Swoo_4448"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4448"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_6"/>
    <dbReference type="OMA" id="NVFQQCV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="327" mass="36032" checksum="65E83FAE412A7B95" modified="2008-04-29" version="1" precursor="true">MGNSAVSVNEVSHHFGDFSALRQVSFSVEQGQTMALLGHNGAGKSTLIKIILGLITPESGEVSLMGAGQCLSSRESRVRLGYLPENVSFYDKLTGEEILTYFAALKGVTKAKVATLIEEFGLGYAKNRQLKTYSKGMKQRLGFAQAILSEPDILMLDEPTVGLDPQASQFLYGKIAELKKTGCAVIVCTHELSLIEPHIDMAMIMAKGERLALGDLNQLRLQSGLKIELKCDGLAQVVKQEPSLLSLYQDDALHFDVEQQEQVVRCLTSQYGKFDFSLSKPGLTQIYRHFIGHDMDSHIGSELTTRITPKESILTRLSSQFLKMRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKA7</accession>
    <name>B1KKA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327064.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4487"/>
    <dbReference type="EnsemblBacteria" id="ACA88738">
        <property type="protein sequence ID" value="ACA88738"/>
        <property type="gene ID" value="Swoo_4487"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4487"/>
    <dbReference type="eggNOG" id="ENOG50312QX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1758068_0_0_6"/>
    <dbReference type="OMA" id="QINGQDY"/>
    <dbReference type="OrthoDB" id="1699767at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764989" evidence="1">
        <location>
            <begin position="22"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="152" mass="16196" checksum="902A023C2BE67955" modified="2008-04-29" version="1" precursor="true">MKLSIFLPAAAVTLFSSLTMANNLPELAAPVEIEASESVVVNGQTFNKVIEPSATADFADTVKLFAGDLVTKGSFNLTSKATGLVFVTLIEGQDAKAVATDLDLKLVFANGNSAVYKAAENVDLLNLNDELFNDSRIKAVKIELANNKYNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKA9</accession>
    <name>B1KKA9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327066.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4489"/>
    <dbReference type="EnsemblBacteria" id="ACA88740">
        <property type="protein sequence ID" value="ACA88740"/>
        <property type="gene ID" value="Swoo_4489"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4489"/>
    <dbReference type="eggNOG" id="ENOG5033RTU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097934_0_0_6"/>
    <dbReference type="OMA" id="IPCWDEV"/>
    <dbReference type="OrthoDB" id="1654302at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd11530">
        <property type="entry name" value="NTP-PPase_DR2231_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033653">
        <property type="entry name" value="NTP-PPase_DR2231-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023292">
        <property type="entry name" value="NTP_PyroPHydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="192" mass="21685" checksum="7D6E9A0F461A8674" modified="2008-04-29" version="1">MKFTALTQPLYDHLYRDIHQFRSTFDLPSEDEATLDDKADTLHTSLAIEELTELAEADTRIEQADAIVDSVYVLMGRLVHLGASQVNDRIEISYIIDLLLNVAKNREIEFITCWDEVHSSNMSKVCRNEKELAETVEFYAKQGVEIVGSQKGDFIIAKCAKDVDMAGKVVRQGKVLKSVYYRPADLAKLVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC2</accession>
    <name>B1KKC2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324108.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1474"/>
    <dbReference type="EnsemblBacteria" id="ACA85762">
        <property type="protein sequence ID" value="ACA85762"/>
        <property type="gene ID" value="Swoo_1474"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1474"/>
    <dbReference type="HOGENOM" id="CLU_2221438_0_0_6"/>
    <dbReference type="OrthoDB" id="2182381at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767431" evidence="1">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="106" mass="11474" checksum="D03887DDFE905621" modified="2008-04-29" version="1" precursor="true">MNRWIVIALFTAISFVASAQPGHWTPYQTIQSIIIENGIALIVVKGGVPTEYIPTACNQAFNQANLSTEHGKAIYSLALAARMSDTPISMALECSGTRPSIKLIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF5</accession>
    <name>B1KKF5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PepSY-associated TM helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324141.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1507"/>
    <dbReference type="EnsemblBacteria" id="ACA85795">
        <property type="protein sequence ID" value="ACA85795"/>
        <property type="gene ID" value="Swoo_1507"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1507"/>
    <dbReference type="eggNOG" id="COG3182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025664_1_0_6"/>
    <dbReference type="OMA" id="WELAVFF"/>
    <dbReference type="OrthoDB" id="1656356at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="481"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="525" mass="58332" checksum="B727B2A408B66D10" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKH2</accession>
    <name>B1KKH2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1524"/>
    <dbReference type="EnsemblBacteria" id="ACA85812">
        <property type="protein sequence ID" value="ACA85812"/>
        <property type="gene ID" value="Swoo_1524"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1524"/>
    <dbReference type="eggNOG" id="COG3956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094174_0_0_6"/>
    <dbReference type="OMA" id="WYPLEHE"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="285" mass="31377" checksum="D75FF6FCEAD1F69F" modified="2008-04-29" version="1">MGMVAGKITIEDSCLSSGVREVNGSLVCVGTGLNLAGQISVLSKSYIENADVVFSLVPDGFAQRWLETLNNDVRSLQPFYAQGDEIKNRRDTYDQMVEAILEQVRAGKRVVCALYGHPGVFACVSHFAIAQALDEGYSAKMEPGISAEACLWADLGIDPGQSGHQSFEASQFMFYKHTPDPTTHLLLWQIGIAGEHTLTEFHTSSDRLQILVEQLNEWYPLEHEITIYEAPTLPIHQARVDKLLLRDLPFARLTSISTLLIPPSSKLEVNHAILGKLGITEVDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKK9</accession>
    <name>B1KKK9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2953"/>
    <dbReference type="EnsemblBacteria" id="ACA87226">
        <property type="protein sequence ID" value="ACA87226"/>
        <property type="gene ID" value="Swoo_2953"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2953"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_378929_0_0_6"/>
    <dbReference type="OMA" id="SIPGYAC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020008">
        <property type="entry name" value="GlyGly_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03501">
        <property type="entry name" value="GlyGly_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00133">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="658"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="773" mass="83902" checksum="004AD6039C606F3F" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKS5</accession>
    <name>B1KKS5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protease 3</fullName>
            <ecNumber evidence="4">3.4.24.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Pitrilysin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Protease III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Protease pi</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Swoo_3021</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.55" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325628.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3021"/>
    <dbReference type="EnsemblBacteria" id="ACA87292">
        <property type="protein sequence ID" value="ACA87292"/>
        <property type="gene ID" value="Swoo_3021"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3021"/>
    <dbReference type="eggNOG" id="COG1025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004639_1_1_6"/>
    <dbReference type="OMA" id="INQVMEH"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="14">
        <location>
            <begin position="28"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="15">
        <location>
            <begin position="186"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_M" evidence="16">
        <location>
            <begin position="371"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="15">
        <location>
            <begin position="652"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACA87292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="929" mass="107819" checksum="062355FD87ADBCAE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKS6</accession>
    <name>B1KKS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3022</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3022"/>
    <dbReference type="EnsemblBacteria" id="ACA87293">
        <property type="protein sequence ID" value="ACA87293"/>
        <property type="gene ID" value="Swoo_3022"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3022"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003758_3_0_6"/>
    <dbReference type="OMA" id="NQHAIKQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011123">
        <property type="entry name" value="Y_Y_Y"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07495">
        <property type="entry name" value="Y_Y_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764620" evidence="1">
        <location>
            <begin position="26"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="952"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="1032"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="1174"/>
            <end position="1428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1441" mass="162202" checksum="E8221F2F004AEEE9" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKY8</accession>
    <name>GLPK_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycerol kinase</fullName>
            <ecNumber evidence="1">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glycerokinase</fullName>
            <shortName evidence="1">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glpK</name>
        <name type="ordered locus">Swoo_4544</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327120.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKY8"/>
    <dbReference type="SMR" id="B1KKY8"/>
    <dbReference type="STRING" id="392500.Swoo_4544"/>
    <dbReference type="PRIDE" id="B1KKY8"/>
    <dbReference type="EnsemblBacteria" id="ACA88794">
        <property type="protein sequence ID" value="ACA88794"/>
        <property type="gene ID" value="Swoo_4544"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4544"/>
    <dbReference type="eggNOG" id="COG0554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_2_3_6"/>
    <dbReference type="OMA" id="FMLMNIG"/>
    <dbReference type="OrthoDB" id="233605at2"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0319">Glycerol metabolism</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000098762" description="Glycerol kinase">
        <location>
            <begin position="1"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="410"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <sequence length="495" mass="54095" checksum="D44BAFEED2822485" modified="2008-04-29" version="1">MTKKYVVALDQGTTSSRAIIFDHDANIVSVSQREFTQIYPQAGWVEHDPMEIWASQSSTLIEVIARSGIHASEIASIGITNQRETTVIWDKQTGKPVYNAIVWQCRRSSEICEELKSQGLEAYIRDTTGLLLDPYFSGTKIKWILDNVSGVRERAERGELLFGTIDTWLVWKLTEGKVHVTDPTNASRTLLFNIHTQSWDKRILEALTIPESLLPQVKPSSAVYGKTRIAGEGGEISIAGIAGDQQSALFGQLCTEPGMAKNTYGTGCFLLMNTGEKAVKSNHGLLTTIAIGAKGEVNYALEGSVFMGGATIQWLRDELGLIRDAQDTEYFASRVESTNGVYLVPAFVGLGAPYWDPSARGALVGLTRGSNRNHIIRAALEAIAYQSRDLLDAMAKDSGVELKKLKVDGGAVANDFLMQFQADITSVEVQRPAVTETTAMGAAFLAGLAVGFWDSTSELKHRADIDKSFMPSISEEQKDELYAGWQKAVSQTING</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ1</accession>
    <name>LEUD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="1">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alpha-IPM isomerase</fullName>
            <shortName evidence="1">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuD</name>
        <name type="ordered locus">Swoo_4547</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327123.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKZ1"/>
    <dbReference type="SMR" id="B1KKZ1"/>
    <dbReference type="STRING" id="392500.Swoo_4547"/>
    <dbReference type="EnsemblBacteria" id="ACA88797">
        <property type="protein sequence ID" value="ACA88797"/>
        <property type="gene ID" value="Swoo_4547"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4547"/>
    <dbReference type="eggNOG" id="COG0066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081378_0_3_6"/>
    <dbReference type="OMA" id="AFTTHTG"/>
    <dbReference type="OrthoDB" id="1384217at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword id="KW-0432">Leucine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000135834" description="3-isopropylmalate dehydratase small subunit">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <sequence length="201" mass="21926" checksum="005BB0A38F1ACFDC" modified="2008-04-29" version="1">MEAFTKHTGLAVMIDSANVDTDQIIPKQFLSKVTRDGFGVHLFHDWRYLDDAGDEPNPEFTLNQSRYKGASILISKENFGCGSSREHAPWALADFGLRAIIAPSFADIFYGNSINNGLLPVRLSDVEVQQLMDEVQANEGAEITVDLEGLTVTSPSGAVFSFEIAGSARHNMLNGLDAIGLTLAYDVQIASYESQLPAWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ6</accession>
    <name>B1KKZ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_4552</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327128.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4552"/>
    <dbReference type="EnsemblBacteria" id="ACA88802">
        <property type="protein sequence ID" value="ACA88802"/>
        <property type="gene ID" value="Swoo_4552"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4552"/>
    <dbReference type="eggNOG" id="COG0514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_14_3_6"/>
    <dbReference type="OMA" id="HHDIPKS"/>
    <dbReference type="OrthoDB" id="54580at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006293">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01389">
        <property type="entry name" value="recQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="34"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="225"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="9">
        <location>
            <begin position="531"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="608" mass="68338" checksum="114B827C30F699C6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA4</accession>
    <name>RSMJ_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase J</fullName>
            <ecNumber evidence="1">2.1.1.242</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA m2G1516 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (guanine-N(2)-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmJ</name>
        <name type="ordered locus">Swoo_0144</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the guanosine in position 1516 of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43220"/>
            <dbReference type="Rhea" id="RHEA-COMP:10412"/>
            <dbReference type="Rhea" id="RHEA-COMP:10413"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.242"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmJ family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.242" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322794.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLA4"/>
    <dbReference type="SMR" id="B1KLA4"/>
    <dbReference type="STRING" id="392500.Swoo_0144"/>
    <dbReference type="EnsemblBacteria" id="ACA84445">
        <property type="protein sequence ID" value="ACA84445"/>
        <property type="gene ID" value="Swoo_0144"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0144"/>
    <dbReference type="eggNOG" id="COG0742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076324_0_0_6"/>
    <dbReference type="OMA" id="SRYDIYP"/>
    <dbReference type="OrthoDB" id="1696461at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008990">
        <property type="term" value="F:rRNA (guanine-N2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01523">
        <property type="entry name" value="16SrRNA_methyltr_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007536">
        <property type="entry name" value="16SrRNA_methylTrfase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36112">
        <property type="entry name" value="PTHR36112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04445">
        <property type="entry name" value="SAM_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000185127" description="Ribosomal RNA small subunit methyltransferase J">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="107"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="123"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="159"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01523"/>
        </source>
    </evidence>
    <sequence length="262" mass="28796" checksum="8E537C5EB847ACA0" modified="2008-04-29" version="1">MTQVNQTKTSYGIFFNRHYPTIESACERWGLVYDANAEFELVFEDNILTLIKRDEPKLKGISVDFVSGAVAHRRKFGGGRGQSIAKAVGLKQGVNPSVVDGTAGLGRDAFVLASLGCNVTMVERHPVVAALLEDGLRRAYEDAEIGDWMRERMKLFHGSSIDSLADAAHSSNTEVDVVYLDPMYPHREKSALVKKEMRVFQSLVGADLDADGLLAPAMALASKRVVVKRPDYAEDLDGVKPSMVIATKKNRFDVYVRAAMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLF5</accession>
    <name>B1KLF5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Flagella basal body P-ring formation protein FlgA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1594</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FlgA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324226.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1594"/>
    <dbReference type="EnsemblBacteria" id="ACA85880">
        <property type="protein sequence ID" value="ACA85880"/>
        <property type="gene ID" value="Swoo_1594"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1594"/>
    <dbReference type="eggNOG" id="COG1261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070510_4_1_6"/>
    <dbReference type="OMA" id="DWKVYVP"/>
    <dbReference type="OrthoDB" id="1521961at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017585">
        <property type="entry name" value="Flag_basal_body_FlgA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039246">
        <property type="entry name" value="Flagellar_FlgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041231">
        <property type="entry name" value="FlgA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36307">
        <property type="entry name" value="PTHR36307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13144">
        <property type="entry name" value="ChapFlgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17656">
        <property type="entry name" value="ChapFlgA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03170">
        <property type="entry name" value="flgA_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5 7" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005122594" description="Flagella basal body P-ring formation protein FlgA" evidence="7">
        <location>
            <begin position="21"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="SAF" evidence="8">
        <location>
            <begin position="113"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="235" mass="25870" checksum="4DBC35E1779DE96E" modified="2008-04-29" version="1" precursor="true">MKVKNVLILFTLLFSTHALSATQASVPSLSTISNLAIETIEKKIDVSGDAKVKITPQSLDTRITPPACFPPVKAELATNRAIKRTNTVKISCDSPQLDYPWQIFLSVRVDILYPVVVARETLGPGDLLSNDDVIIEYVDRTNLRGQQFDDIKQVVGTRVKRRIPPNQPIFSSNLCFVCKGDTVSIYARSANVVIKTVGEALRDGNLGDRIRIKNTHSNKSLHATVTGVGEVEVRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI5</accession>
    <name>B1KLI5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flagellar protein FliL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1624</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Controls the rotational direction of flagella during chemotaxis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324256.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1624"/>
    <dbReference type="EnsemblBacteria" id="ACA85910">
        <property type="protein sequence ID" value="ACA85910"/>
        <property type="gene ID" value="Swoo_1624"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1624"/>
    <dbReference type="eggNOG" id="COG1580">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099018_4_0_6"/>
    <dbReference type="OMA" id="HMPLIRN"/>
    <dbReference type="OrthoDB" id="1873899at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005503">
        <property type="entry name" value="FliL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35091">
        <property type="entry name" value="PTHR35091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03748">
        <property type="entry name" value="FliL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="172" mass="18705" checksum="455AFEFED91D21D3" modified="2008-04-29" version="1">MADEESLELEENGEPKSKKKLIFGVIGLVLLLAIGGGVWFFLGSSEPSDEAAVEGEAAEVVEEVNTGEAFYVGMPRPFLFNLPGASRSRLVEIKVQLMVRGGDDDVLIKKHIPLIEDALLTTFSSADVQKMSSLAGKDELRQLALLNVQNTLQPVTGRKVVEKVLFTGFVMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLN8</accession>
    <name>B1KLN8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325671.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87335">
        <property type="protein sequence ID" value="ACA87335"/>
        <property type="gene ID" value="Swoo_3064"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3064"/>
    <dbReference type="eggNOG" id="ENOG5032959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_854990_0_0_6"/>
    <dbReference type="OMA" id="QHAGMAS"/>
    <dbReference type="OrthoDB" id="1846931at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="36831" checksum="35D09BCA60D316CC" modified="2008-04-29" version="1">MNSYLVSDKPIIYADMNVFRYLACGDISILEPERFKWVYSYVHLDEIHRNGNQDALEGMTLLKAVEICDVLNQDFQSEGNIVIRDYIDPYLRYEEHLEAISGYEGAADHMVEHLIRSFGADNFKELSETPEQMRNEIERITSIIPDERREDLIEKVSKVSKEMEATIEKHLKNKMPVDKTRSALGVTSENRKAIEKSEFAIDEVWDLISPSIPNVTKNQFFGFEPIPGIEGVQHTQHGAISGAYIVLNMIGISPDKGLAKRDKIKNIMSDGQHAGMASYCNALVSADRGIINKSSCIFLYLKNITNALHFEYQKGYQLSLGVSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLS3</accession>
    <name>B1KLS3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage shock protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3099"/>
    <dbReference type="EnsemblBacteria" id="ACA87370">
        <property type="protein sequence ID" value="ACA87370"/>
        <property type="gene ID" value="Swoo_3099"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3099"/>
    <dbReference type="eggNOG" id="ENOG5032YI2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178570_0_0_6"/>
    <dbReference type="OMA" id="LWLHYSQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009271">
        <property type="term" value="P:phage shock"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009554">
        <property type="entry name" value="Phageshock_PspB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06667">
        <property type="entry name" value="PspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02976">
        <property type="entry name" value="phageshock_pspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="75" mass="8871" checksum="2C1445CE63C91141" modified="2008-04-29" version="1">MDILMAPIIIFLIFVAPIWLILHYRSKRQVSQGLTEEEFTQLNELITRADKMAQRIETLEAILDTEAPQWRTRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV5</accession>
    <name>B1KLV5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA (guanosine(18)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA [Gm18] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmH</name>
        <name evidence="7" type="ordered locus">Swoo_4585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:20077"/>
            <dbReference type="Rhea" id="RHEA-COMP:10190"/>
            <dbReference type="Rhea" id="RHEA-COMP:10192"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="EC" id="2.1.1.34"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.34" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327160.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4585"/>
    <dbReference type="EnsemblBacteria" id="ACA88835">
        <property type="protein sequence ID" value="ACA88835"/>
        <property type="gene ID" value="Swoo_4585"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4585"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_4_2_6"/>
    <dbReference type="OMA" id="TDRYQHV"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009020">
        <property type="term" value="F:tRNA (guanosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052665">
        <property type="term" value="F:tRNA (uracil-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002938">
        <property type="term" value="P:tRNA guanine ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18092">
        <property type="entry name" value="SpoU-like_TrmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02060">
        <property type="entry name" value="tRNA_methyltr_TrmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022724">
        <property type="entry name" value="rRNA_MeTrfase_SpoU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033671">
        <property type="entry name" value="TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43453">
        <property type="entry name" value="PTHR43453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12105">
        <property type="entry name" value="SpoU_methylas_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="SpoU_methylas_C" evidence="6">
        <location>
            <begin position="163"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="231" mass="25952" checksum="4A045BDF77DF522C" modified="2008-04-29" version="1">MSPERFARINKMLDNRQPDLTLCLDKVHKTNNIAAVIRTADAVGVHQIHAVWPDIEMRVSGNTASGSQQWVKTIKHYHMDDAQQAFRAQNMQVLATTFSETAVDFREIDYTRPTAIILGNERDGVSQEGIAAAGQHIIIPMIGMVQSLNVSVASALVMYEAQRQRTAAGMYGTRKLDEAYCQKMLFEQGHPIYAKACRRKSIPYPAVDMEGQIVASDEWWERMRAPEVESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLY2</accession>
    <name>B1KLY2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327187.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4612"/>
    <dbReference type="EnsemblBacteria" id="ACA88862">
        <property type="protein sequence ID" value="ACA88862"/>
        <property type="gene ID" value="Swoo_4612"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4612"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_6"/>
    <dbReference type="OMA" id="MNNNFAF"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="4">
        <location>
            <begin position="5"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="409" mass="43684" checksum="7F20AAA0B46E6A83" modified="2008-04-29" version="1">MSRRVVITGFGGISCLGDNWESMASSLKAQKNFVVTMDEWDKFDGLNTRLAAPVTDFEKPAHYSRKKIRSMGRVSLMATRASELALIDANLLDSPVVTSGAMGVAYGSSTGSTDPLIAFGDMLKEGDMSGVTATSYIRMMAHTTAVNVGVFFGLKGRVHTTSSACTSGSQGIGYAYEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNETPELTPRPFDKNRDGLVIGEGACTLVLEELEHATARGAKIYAEIVGFGTNSDGLHVTQPNSATMEIAIRHALKDAGLPPESIGYVNAHGTATDRGDIAETQATNAVFGPTMPISSLKSYTGHTLGACGALEAWCSVEMMNAGWFAPSLNLTDIDPECGELDYIKGEIRHIETNYVMSNNFAFGGINTSLIFKRWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM06</accession>
    <name>B1KM06_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327210.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4636"/>
    <dbReference type="EnsemblBacteria" id="ACA88886">
        <property type="protein sequence ID" value="ACA88886"/>
        <property type="gene ID" value="Swoo_4636"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4636"/>
    <dbReference type="HOGENOM" id="CLU_2571963_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="81" mass="9201" checksum="D531C7639988221C" modified="2008-04-29" version="1">MFSINFTFQHYFFFTSLIAIPLTLLTILGRFILVKMGYIGVDITFTWQRLIAEFAIILVGSYVLVCALAMLTLIVGLFLSE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM34</accession>
    <name>RL17_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplQ</name>
        <name type="ordered locus">Swoo_4664</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327238.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KM34"/>
    <dbReference type="SMR" id="B1KM34"/>
    <dbReference type="STRING" id="392500.Swoo_4664"/>
    <dbReference type="EnsemblBacteria" id="ACA88914">
        <property type="protein sequence ID" value="ACA88914"/>
        <property type="gene ID" value="Swoo_4664"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4664"/>
    <dbReference type="eggNOG" id="COG0203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074407_2_2_6"/>
    <dbReference type="OMA" id="YAVTELF"/>
    <dbReference type="OrthoDB" id="1838961at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000144484" description="50S ribosomal protein L17">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <sequence length="132" mass="14891" checksum="792E7BDE7DD9922C" modified="2008-04-29" version="1">MRHRKSGRQLNRNSSHRQAMFRNMASSLVRHEVIKTTVAKAKELRRVVEPLITLAKSDSVANRRLAFARTRDAEVVGKLFNELGPRYQERPGGYTRILKCGLRTGDKAPMAYIELVGRPEDAEAVEADDSAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM44</accession>
    <name>BIOH_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pimeloyl-[acyl-carrier protein] methyl ester esterase</fullName>
            <ecNumber evidence="2">3.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Biotin synthesis protein BioH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Carboxylesterase BioH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bioH</name>
        <name type="ordered locus">Swoo_0156</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-carboxyhexanoyl-[ACP] methyl ester + H2O = 6-carboxyhexanoyl-[ACP] + H(+) + methanol</text>
            <dbReference type="Rhea" id="RHEA:42700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="Rhea" id="RHEA-COMP:10186"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:82735"/>
            <dbReference type="EC" id="3.1.1.85"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.85" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322806.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KM44"/>
    <dbReference type="SMR" id="B1KM44"/>
    <dbReference type="STRING" id="392500.Swoo_0156"/>
    <dbReference type="ESTHER" id="shewm-bioh">
        <property type="family name" value="BioH"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84457">
        <property type="protein sequence ID" value="ACA84457"/>
        <property type="gene ID" value="Swoo_0156"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0156"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_12_2_6"/>
    <dbReference type="OMA" id="LHGWGMN"/>
    <dbReference type="OrthoDB" id="1282004at2"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01260">
        <property type="entry name" value="Carboxylester"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010076">
        <property type="entry name" value="BioH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01738">
        <property type="entry name" value="bioH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0093">Biotin biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0719">Serine esterase</keyword>
    <feature type="chain" id="PRO_1000140004" description="Pimeloyl-[acyl-carrier protein] methyl ester esterase">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="16"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="80"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="143"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01260"/>
        </source>
    </evidence>
    <sequence length="256" mass="28558" checksum="F493E3EB3974EBB5" modified="2008-04-29" version="1">MSSSLHIESIGQGQELVILHGWGVNSSVFTPLHASLSEYRVHYVDLPGFGHSDPIDGDLDDWVDAIINQLPNTAIWIGWSLGGLVATKAALRYPEQVRGLVTIASSPCFMAREDESWPGIPPQVLSQFSTQLQQNIGKTIERFLAIQVMGSATAKEDIKQLKELVLSRPLPKNSALAQGLKMLENIDLRAQLPQIEQPWLRVWGRLDGLVPRRVPPLMPNHQAHFTDLLLPKASHAPFLSHRDEFLTGLTDWLNKF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-07-01" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM97</accession>
    <name>MEND_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase</fullName>
            <shortName evidence="1">SEPHCHC synthase</shortName>
            <ecNumber evidence="1">2.2.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Menaquinone biosynthesis protein MenD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">menD</name>
        <name type="ordered locus">Swoo_0209</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="2.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="1">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family. MenD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322859.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KM97"/>
    <dbReference type="SMR" id="B1KM97"/>
    <dbReference type="STRING" id="392500.Swoo_0209"/>
    <dbReference type="EnsemblBacteria" id="ACA84510">
        <property type="protein sequence ID" value="ACA84510"/>
        <property type="gene ID" value="Swoo_0209"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0209"/>
    <dbReference type="eggNOG" id="COG1165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006051_3_0_6"/>
    <dbReference type="OMA" id="FCNRGTS"/>
    <dbReference type="OrthoDB" id="897995at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070204">
        <property type="term" value="F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01659">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004433">
        <property type="entry name" value="MenaQ_synth_MenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032264">
        <property type="entry name" value="MenD_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916">
        <property type="entry name" value="PTHR42916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16582">
        <property type="entry name" value="TPP_enzyme_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004983">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00173">
        <property type="entry name" value="menD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000341842" description="2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase">
        <location>
            <begin position="1"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01659"/>
        </source>
    </evidence>
    <sequence length="569" mass="62682" checksum="1A4353D9465A0A12" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI4</accession>
    <name>B1KMI4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324328.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1697"/>
    <dbReference type="EnsemblBacteria" id="ACA85982">
        <property type="protein sequence ID" value="ACA85982"/>
        <property type="gene ID" value="Swoo_1697"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1697"/>
    <dbReference type="eggNOG" id="COG3307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054947_0_0_6"/>
    <dbReference type="OMA" id="MPIGSHH"/>
    <dbReference type="OrthoDB" id="819740at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="418" mass="46850" checksum="25F04B7C9944FC02" modified="2008-04-29" version="1">MGSKRFNPDPTAMNTDEKIIWYSITYTYLFWVLGAMYIVAPVIGWILLLRMAKRYIFEREDFVLTPAQLCWIFGMCTMLIALVIAHFDFELGTPKLIKSSIGWAKGWALLAVFPLLGSLKIRPELIYRACCIVCKHTLIILPFCILAWLVGLPSTLYVSPLSIIGGPGPEFFSVSLYEIDPGSGTPRWRLFTPWAPALGMMGNLFLNFAIQEKERRYKVYGVLGSLVMILVSQSRLAIVCYFLLLGYFAFIRWHRSPWLYFLASPSVLLLGLVGIQVIEKIELSIAAIKSARAGSTRVREHLGQIALQRWSNEALVWGHGIVERGPHLVEYMPIGSHHTWFGLLFVKGLVGAIALALPLICSLLSLISEISKSPVAASAIAVLLQIFLYTFGENLEILAYLFWPGLIIVGIAHKRKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KML9</accession>
    <name>B1KML9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325733.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3126"/>
    <dbReference type="EnsemblBacteria" id="ACA87397">
        <property type="protein sequence ID" value="ACA87397"/>
        <property type="gene ID" value="Swoo_3126"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3126"/>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045390_0_0_6"/>
    <dbReference type="OMA" id="GHHDNAD"/>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020015">
        <property type="entry name" value="Decahaem_cyt-c_DmsE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010177">
        <property type="entry name" value="Paired_CXXCH_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09699">
        <property type="entry name" value="Paired_CXXCH_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03508">
        <property type="entry name" value="decahem_SO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01905">
        <property type="entry name" value="paired_CXXCH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764676" evidence="1">
        <location>
            <begin position="35"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="2">
        <location>
            <begin position="94"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="2">
        <location>
            <begin position="153"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="2">
        <location>
            <begin position="201"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Paired_CXXCH_1" evidence="2">
        <location>
            <begin position="248"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="333" mass="36029" checksum="C0D730F1DA3FB630" modified="2008-04-29" version="1" precursor="true">MKIIKTMKKFSTGMLPALMVSAILSLGFATSATASKWDAKMTPDEVEATLDKKFAEGKYSPKGADSCLMCHRRSEKVMDIFKGVHGAIDSSKSPMAGLQCESCHGPQGNHNKGGNEPMIAFGPQSTLSAEKQNSVCMSCHQDDKRMAWNGGHHDNADVACASCHSVHTEKDPVLSKNTEMEVCTSCHTKQKADMNKRSSHPMKWNQMVCSDCHNPHGTMSDSDLVKPSVNETCYSCHAEKRGPKLWEHAPVTEDCVTCHNPHGSVNDAMLKTRAPQLCQQCHASDGHASNAYLGNTSQGASVGGNAFTGGRSCLNCHNQIHGSNHPSGKLFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMM7</accession>
    <name>B1KMM7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycerate kinase</fullName>
            <ecNumber evidence="5">2.7.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycerate kinase type-1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.31" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325741.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3134"/>
    <dbReference type="EnsemblBacteria" id="ACA87405">
        <property type="protein sequence ID" value="ACA87405"/>
        <property type="gene ID" value="Swoo_3134"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3134"/>
    <dbReference type="eggNOG" id="COG1929">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028255_0_0_6"/>
    <dbReference type="OMA" id="YTAVHEK"/>
    <dbReference type="OrthoDB" id="1292731at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031388">
        <property type="term" value="P:organic acid phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018193">
        <property type="entry name" value="Glyc_kinase_flavodox-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004381">
        <property type="entry name" value="Glycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018197">
        <property type="entry name" value="Glycerate_kinase_RE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036129">
        <property type="entry name" value="Glycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21599">
        <property type="entry name" value="PTHR21599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02595">
        <property type="entry name" value="Gly_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006078">
        <property type="entry name" value="GlxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110738">
        <property type="entry name" value="SSF110738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00045">
        <property type="entry name" value="TIGR00045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR006078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="392" mass="41106" checksum="65B78BD5332D4622" modified="2008-04-29" version="1">MKIVIAPDSFKESLSAMEVADEIERGFKMVLPDAEFIKLPVADGGEGTVQSMVDATQGSIINLEVTGPLGNRVHAHYGILGDNDDNAVKTAVIEMASASGLHHVPIHLRDPLITTSYGTGELICNALNRGIKRILIGLGGSATNDGGAGMAQALGVHLLDKKGNPLPVGGASLQQLERIDLKDIHPLIAECEFEVACDVDNPLCGEKGASAIFGPQKGASPEVVSILDAALTRYADIIAQHPLPDRRNMAGSGAAGGMGLGVMAFLGASLRPGIDIVMETVKLDEKIKGAQLVITGEGRLDSQTLHGKTPMGVTRIANALQIPVIAIAGCVSDDANILLKHGISAIFSITPRALPIEEVLASAKHNLFTTSHNIAALYAQTTSRCRIQHVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMR1</accession>
    <name>B1KMR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3168</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325775.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3168"/>
    <dbReference type="EnsemblBacteria" id="ACA87439">
        <property type="protein sequence ID" value="ACA87439"/>
        <property type="gene ID" value="Swoo_3168"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3168"/>
    <dbReference type="eggNOG" id="COG4590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013803_0_0_6"/>
    <dbReference type="OMA" id="WGKVWYE"/>
    <dbReference type="OrthoDB" id="1325025at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="521"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="717"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="450"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="752" mass="83115" checksum="3A02F46D616985A1" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN19</accession>
    <name>B1KN19_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Type II secretion system protein L</fullName>
            <shortName evidence="11">T2SS protein L</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_4726</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GSP L family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4726"/>
    <dbReference type="EnsemblBacteria" id="ACA88976">
        <property type="protein sequence ID" value="ACA88976"/>
        <property type="gene ID" value="Swoo_4726"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4726"/>
    <dbReference type="eggNOG" id="COG3297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041016_2_1_6"/>
    <dbReference type="OMA" id="PLELPMQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024230">
        <property type="entry name" value="GspL_cyto_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025691">
        <property type="entry name" value="GspL_pp_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007812">
        <property type="entry name" value="T2SS_protein-GspL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12693">
        <property type="entry name" value="GspL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05134">
        <property type="entry name" value="T2SSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015761">
        <property type="entry name" value="Protein_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01709">
        <property type="entry name" value="typeII_sec_gspL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSL" evidence="13">
        <location>
            <begin position="7"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="GspL_C" evidence="14">
        <location>
            <begin position="244"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA88976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="399" mass="43737" checksum="77248212445F26F4" modified="2008-04-29" version="1">MNVSERLFIRLGTSSDQACSWLVWSEQEQEIIASGELKDASALSSLTERAGNRPVDVLVPSSAITLTSVELPEKGQRQAIQALPFMLEESLAENVDELHFVPGPRTDGELSVAVVAHQQMQDWLSWLHEAGLKVKNVVPDCLALPLDECQWAAIKFNQEYLVRTGEGSGVSLTQDWLDTLLPRLLPEGQETPVTVAGHSELAFAGADIKPQALELPMLVLAKGILSAPLNLLSGVYTPKREYGKNLLLWRNVAIVIGVALVLGLVNKGLNIHQMNTEQARLKAESEAIYKRAVPGSSRIVNLRSQMEKQLRSMQGGSGGSEFFTMLQGLEPAFTQVPELKPTTLRFDSVRNELRMQVIAKSYAQVEQFKTIVSASYQLDSGAMNSGEDSVTSTLTLRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN40</accession>
    <name>B1KN40_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327314.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88997">
        <property type="protein sequence ID" value="ACA88997"/>
        <property type="gene ID" value="Swoo_4748"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4748"/>
    <dbReference type="HOGENOM" id="CLU_1546563_0_0_6"/>
    <dbReference type="OMA" id="ICAMESF"/>
    <dbReference type="OrthoDB" id="2038197at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="173" mass="19758" checksum="1B4E445C64A17F2E" modified="2008-04-29" version="1">MNKDDLNWSAIPNLASQIRVCDESGLITPSLAMCFISIDSLASLSRPIDKARVTRIDFITWVDRYLRCHPEQTYKYNGKDVYAARCSFLHTYGATSELHEKDTTTIKFVYHDGGRHAYKPEINSALVVIGVRSFTNDVICAMESFMAECEKDKELRARVESRLNELFNIIPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KND2</accession>
    <name>B1KND2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetylornithine deacetylase (ArgE)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0328</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family. ArgE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322978.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0328"/>
    <dbReference type="EnsemblBacteria" id="ACA84629">
        <property type="protein sequence ID" value="ACA84629"/>
        <property type="gene ID" value="Swoo_0328"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0328"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_2_4_6"/>
    <dbReference type="OMA" id="CAHQPGE"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008777">
        <property type="term" value="F:acetylornithine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01108">
        <property type="entry name" value="ArgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010169">
        <property type="entry name" value="AcOrn-deacetyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF1">
        <property type="entry name" value="PTHR43808:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01892">
        <property type="entry name" value="AcOrn-deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="4">
        <location>
            <begin position="177"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="383" mass="42074" checksum="52F8A9F7CB741CBE" modified="2008-04-29" version="1">MASLADLKSNFSQLIASPSISALEVEQDMSNQGVIDLLQTWFSELGFECKAQAVKDSRSKHNLVASLGSGKGGLLLAGHTDTVPFDEGRWSQDPFTLTEKDNRWYGLGTCDMKGFFALVLEALKDMPLAQFKRPLHILASADEETTMNGAKAFAQQKSIAPDYAIIGEPTSLKPVYMHKGHLTQGIRVIGKSGHSSDPAKGVNAIEIMHLVMGQLLKLKQHLADNYREEAFSVPYPTMNFGHVHGGDAANRICGCCDLHIDIRPLPGLELEILEQMVMNYLKPINDQYPGCINVAPLYPGSEPFADSRENSWSKLVAELSANAPEVVNYATEAPYISKLGCQTLVLGPGSIEQAHQPDEYLDTQYLNKTVELLKQLIYHACIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNQ4</accession>
    <name>B1KNQ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transferase hexapeptide repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325848.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3242"/>
    <dbReference type="EnsemblBacteria" id="ACA87512">
        <property type="protein sequence ID" value="ACA87512"/>
        <property type="gene ID" value="Swoo_3242"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3242"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_7_1_6"/>
    <dbReference type="OMA" id="NHGCSLD"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="204" mass="22099" checksum="945093242A782D9C" modified="2008-04-29" version="1">MTVPDYQAQHKKRLSYMPWLYFSLKPKLLSWAQPWQKQVQAEFMALETVTFGDNCFIAPEVKLFAEPGRDIAIGSHCMIAADSFLHGPISLGDEVAINHGCSLDGGRNGIKIGKQTRIANNVTIYAFNHGMAPDTPIYQQASNSKGVTIGKDVWIGAQAGIVDGVSIGDHAVIGMGCIVTKDVADFAIVAGNPAKVIGDRRDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS0</accession>
    <name>B1KNS0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dipeptide epimerase</fullName>
            <ecNumber evidence="5">5.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3258</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4 5">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the mandelate racemase/muconate lactonizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325864.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3258"/>
    <dbReference type="EnsemblBacteria" id="ACA87528">
        <property type="protein sequence ID" value="ACA87528"/>
        <property type="gene ID" value="Swoo_3258"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3258"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_4_3_6"/>
    <dbReference type="OMA" id="DIVDHRH"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016855">
        <property type="term" value="F:racemase and epimerase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03319">
        <property type="entry name" value="L-Ala-DL-Glu_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034603">
        <property type="entry name" value="Dipeptide_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00010">
        <property type="entry name" value="dipeptide_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="6">
        <location>
            <begin position="143"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (R)-substrate epimerization" evidence="3">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (S)-substrate epimerization" evidence="3">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="355" mass="38467" checksum="7EDCD69D0AD1896B" modified="2008-04-29" version="1">MIDSTKRLHFYGEDFELIAIQQSIPLKQVFRIARGAKNAAQVIVVIIKYQGVIGWGESVPYARYGETIEGIISSIKTVCTHAKRFTDFANAISAHSQGAAQNALDCAYLDLQAKLTGIATQARFNLPKTRAVITAQTLSIDTPEAMAEAAKPLAKAPLIKVKLDNIDIVEKMTAIYAMAPHSQFIVDANEAWSIEDLKLCADKLAALNVVLIEQPLPAEKDEALASLTINIALCADESCHTVKDLSALSGKYDVVNIKLDKTGGLNQAVALAAQAKEMGFDIMLGCMVGSSLAMAPAFLLTPFAKYIDLDGPLLVKEDRLVSFDIDNGLMQPFNEQLWGGVDLESNIEADQLIKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNT7</accession>
    <name>DXR_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="1">DXP reductoisomerase</shortName>
            <ecNumber evidence="1">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dxr</name>
        <name type="ordered locus">Swoo_3275</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DXR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325881.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNT7"/>
    <dbReference type="SMR" id="B1KNT7"/>
    <dbReference type="STRING" id="392500.Swoo_3275"/>
    <dbReference type="EnsemblBacteria" id="ACA87545">
        <property type="protein sequence ID" value="ACA87545"/>
        <property type="gene ID" value="Swoo_3275"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3275"/>
    <dbReference type="eggNOG" id="COG0743">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035714_4_0_6"/>
    <dbReference type="OMA" id="PIDSEHF"/>
    <dbReference type="OrthoDB" id="1200722at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000098515" description="1-deoxy-D-xylulose 5-phosphate reductoisomerase">
        <location>
            <begin position="1"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <sequence length="395" mass="42650" checksum="BB92327CD221FCF4" modified="2008-04-29" version="1">MQSMVILGATGSIGASTLSVIASNPETYSVYALVANTNVDKMMALCEQYRPKVAHMVDEQAAKSLQERLSPSLKIEVTTGESQLESIVTSSCVDTVMAAIVGAAGLVPTLAAVKAGKRVLLANKESLVMSGRLFIEEMKKSGAQVLPVDSEHNAIFQALPEPVQQEIGFCDLDEAGISHILLTGSGGPFLTSPLSSLPQMTPAQACKHPNWSMGRKISVDSASMMNKGLEYIEARWLFNASAEQLKVVIHPQSVIHSMVQYRDGSVIAQLGNPDMRTPIAHCMSYPQRINSGVEPLDFFKVGQLSFLEPDFTRFPCLALAIDACNQGQEATTILNAANEISVAAFLDNKIKFTDIAKVNETCLSQVAKQALNSIDDILALDVQTRTYASEWVNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP10</accession>
    <name>B1KP10_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Molybdenum cofactor biosynthesis protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_4792</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May be involved in the biosynthesis of molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MoaB/Mog family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327358.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4792"/>
    <dbReference type="EnsemblBacteria" id="ACA89041">
        <property type="protein sequence ID" value="ACA89041"/>
        <property type="gene ID" value="Swoo_4792"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4792"/>
    <dbReference type="eggNOG" id="COG0521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077358_2_2_6"/>
    <dbReference type="OMA" id="TGWDGIL"/>
    <dbReference type="OrthoDB" id="1528139at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012245">
        <property type="entry name" value="MoaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013484">
        <property type="entry name" value="MoaB_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43232">
        <property type="entry name" value="PTHR43232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006443">
        <property type="entry name" value="MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02667">
        <property type="entry name" value="moaB_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="6">
        <location>
            <begin position="15"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA89041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="174" mass="19312" checksum="79BFC17850A355C1" modified="2008-04-29" version="1">MGHCTTSQFIPLNIAVLTLSDSRDLTQDTSGQFLEDNLIEAGHKLVDRKLIKDDKYAIRSQLSQWIASNEVQVVITTGGTGFTERDNTPEAVKPLFDREIEGFGELFRHITFTELGTSTVQSRALGGFANQTAIFCLPGSTGACRTGWTKILKEQLDARHRPCNFVMHVKKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP28</accession>
    <name>B1KP28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formate dehydrogenase region TAT target</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327376.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4810"/>
    <dbReference type="EnsemblBacteria" id="ACA89059">
        <property type="protein sequence ID" value="ACA89059"/>
        <property type="gene ID" value="Swoo_4810"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4810"/>
    <dbReference type="eggNOG" id="ENOG5033B11">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180794_1_0_6"/>
    <dbReference type="OMA" id="DGYHETA"/>
    <dbReference type="OrthoDB" id="2071796at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014177">
        <property type="entry name" value="Formate_DH_TAT-contain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036704">
        <property type="entry name" value="UCP036704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02811">
        <property type="entry name" value="formate_TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767258" evidence="1">
        <location>
            <begin position="29"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="65" mass="6966" checksum="E6758D00AF9225F9" modified="2008-04-29" version="1" precursor="true">MKKQQPDLNRRSLLKALTIGGTATVALAATGISAAQATESNVSAKSTDGYHETNHIRSYYNSLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP35</accession>
    <name>B1KP35_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327383.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4817"/>
    <dbReference type="EnsemblBacteria" id="ACA89066">
        <property type="protein sequence ID" value="ACA89066"/>
        <property type="gene ID" value="Swoo_4817"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4817"/>
    <dbReference type="eggNOG" id="ENOG5032ZGA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1389384_0_0_6"/>
    <dbReference type="OMA" id="DYDHDYK"/>
    <dbReference type="OrthoDB" id="1400096at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021735">
        <property type="entry name" value="DUF3306"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11748">
        <property type="entry name" value="DUF3306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="197" mass="21862" checksum="690056C1F2B7750E" modified="2008-04-29" version="1">MSGSGGFLSRWNLRRQKVEDEKLAEESEAVSQQAEPIEKSLDTESVDEQQLETELEAQSQPITAEELPDPEKIEIGGSFASFMGANVDPTAKAAALRALWKQPQYNEIDGLLEYALDYSNQPKLTPEHSAEIAKKIFRHVTKSDDEEVEATETELAQETAEETNLLSETTEDILDGDHVQVSQNEPEPCDEVKPSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPG8</accession>
    <name>B1KPG8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxoglutarate dehydrogenase (succinyl-transferring)</fullName>
            <ecNumber evidence="4">1.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1837</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324467.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1837"/>
    <dbReference type="EnsemblBacteria" id="ACA86121">
        <property type="protein sequence ID" value="ACA86121"/>
        <property type="gene ID" value="Swoo_1837"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1837"/>
    <dbReference type="eggNOG" id="COG0567">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004709_1_0_6"/>
    <dbReference type="OMA" id="RDSYCRT"/>
    <dbReference type="OrthoDB" id="29166at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="7">
        <location>
            <begin position="599"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="940" mass="105252" checksum="D0900158E65BF827" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPL8</accession>
    <name>B1KPL8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ykof domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324517.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1887"/>
    <dbReference type="EnsemblBacteria" id="ACA86171">
        <property type="protein sequence ID" value="ACA86171"/>
        <property type="gene ID" value="Swoo_1887"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1887"/>
    <dbReference type="eggNOG" id="ENOG50330AE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_191614_0_0_6"/>
    <dbReference type="OMA" id="TQVCGEY"/>
    <dbReference type="OrthoDB" id="1800854at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011522">
        <property type="entry name" value="Thiamin/HMP-bd_put_YkoF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07615">
        <property type="entry name" value="Ykof"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="SSF89957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ykof" evidence="1">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="86" mass="9922" checksum="47B6231150CED677" modified="2008-04-29" version="1">MKLTAEISCYPLQDNYLDPIRWFIGRVDSYKNIERKTNAMATQVCGEYREVMDMLATEMEAAHKKWGKAVFVCKFIGGELNLSHSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ42</accession>
    <name>B1KQ42_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable chromosome-partitioning protein ParB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_4906</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327471.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4906"/>
    <dbReference type="EnsemblBacteria" id="ACA89155">
        <property type="protein sequence ID" value="ACA89155"/>
        <property type="gene ID" value="Swoo_4906"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4906"/>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023853_0_0_6"/>
    <dbReference type="OMA" id="IALSYQR"/>
    <dbReference type="OrthoDB" id="653368at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="5">
        <location>
            <begin position="44"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA89155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="32623" checksum="7E1EA01B3E28B89B" modified="2008-04-29" version="1" precursor="true">MTVKKRGLGKGLDALLSTSSAASAKLNQGQSDSTDQDIKNDDLIMLDVDMMQSGKYQPRKDMSPEALDELSESIKAQGVIQPILVRKVSPTMYEIIAGERRWRAAQLAKLSKVPCIVKQVPDESAVVIALIENIQREDLNAMEEAIALERLMQEFNLTHQLIADAVGKSRATVSNLLRLNGLNEPVKRMLEYGDIDMGHARALLAIDGEEQTVIARMVAAKELTVRETERLVNKTLNPPEIADKPAKDHDVARLESQLIERLGAKVSITHNKKGKGKLVINYQDLAELDGIISKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ98</accession>
    <name>B1KQ98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323102.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84753">
        <property type="protein sequence ID" value="ACA84753"/>
        <property type="gene ID" value="Swoo_0455"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0455"/>
    <dbReference type="eggNOG" id="ENOG502ZB8R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_911825_0_0_6"/>
    <dbReference type="OMA" id="YNDPYEL"/>
    <dbReference type="OrthoDB" id="1322447at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021352">
        <property type="entry name" value="DUF2971"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11185">
        <property type="entry name" value="DUF2971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="34874" checksum="86718DFC5C1027E7" modified="2008-04-29" version="1">MSKIYKYFGSSVFELVFDKEGFCGVKCSLPKDYNDPYELFLAMDLNVPTEYLAFYNDVIQEMPQFPTSCFSKSPIVSPMWAHYANNHTGFAIEFDLEKLQQHFDGNPFWGVDYREEPHKSLGDIVQRAAELKKPRYTYDLQRFAFSEAYFSKYAQWSYEEELRFVDTTGVTEKAAGNDILYIPMDCLVSVIVGPKSDEQLITSSQKAVEECGLNWYQLVIGKSHPQPYFRSIDGTICTFKDGDVLAHDELCDRCEEPINSGSEMCPLCSITEAHAIEAAAGNPFRLISEAGQLEGYMRSMDAIHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB9</accession>
    <name>B1KQB9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Type I secretion system ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0476</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323123.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0476"/>
    <dbReference type="EnsemblBacteria" id="ACA84774">
        <property type="protein sequence ID" value="ACA84774"/>
        <property type="gene ID" value="Swoo_0476"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0476"/>
    <dbReference type="eggNOG" id="COG2274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_95_6_6"/>
    <dbReference type="OMA" id="HWFWSTL"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017750">
        <property type="entry name" value="ATPase_T1SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03375">
        <property type="entry name" value="type_I_sec_LssB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="10">
        <location>
            <begin position="18"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="176"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="488"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="522"/>
            <end position="529"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="726" mass="79243" checksum="7AC6F1877E10184C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC5</accession>
    <name>B1KQC5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="1">4.2.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydroxymethylbilane = H2O + uroporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323129.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0482"/>
    <dbReference type="EnsemblBacteria" id="ACA84780">
        <property type="protein sequence ID" value="ACA84780"/>
        <property type="gene ID" value="Swoo_0482"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0482"/>
    <dbReference type="eggNOG" id="COG1587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_9_4_6"/>
    <dbReference type="OMA" id="HPRIAQA"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042">
        <property type="entry name" value="PTHR38042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEM4" evidence="2">
        <location>
            <begin position="14"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="243" mass="26754" checksum="3EAEE62B7A07A406" modified="2008-04-29" version="1">MKLLLTRPKGRNQSMSEALTQLGVPYIITPLLEVQASKTHQDQDAIAHFNAADIIIFISTNAVEFSSQVIELKKHKTAQFYAVGDATFQALKALGIDAFAAPSDCQQTEGLLTLADLQELTGQNIMIVRGVGGRETLAEKLTQRGAKVNYWETYQRACPAINERTPYLWHDEKVDTIIITSGEILHSLIKLVPKELFAWLRACHIIVPSSRVKEQALAYGLEHVTNAKAANSKAMLSALGLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH8</accession>
    <name>B1KQH8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324563.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1933"/>
    <dbReference type="EnsemblBacteria" id="ACA86217">
        <property type="protein sequence ID" value="ACA86217"/>
        <property type="gene ID" value="Swoo_1933"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1933"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_35_2_6"/>
    <dbReference type="OMA" id="KNALEMG"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="34077" checksum="75C45897106D3E0B" modified="2008-04-29" version="1">MRIDVDTFKVLEILVEEGSFAKAAERLHKAQSAVSYQVKKLEHHLGVKLFCRDQYRAELTPEGRVILAEGQKLLQYLANIEHLASKFSDGWEPKLELIVDGSLPMEPIMKALKRMTLENIPTKIQLNVEFLAGVQARFERDQADLMLVKDYRTGPHYRPQSLPDITTILVVSSSHPLANTHDVSLLELQSHVELTIEDSSSDIHYHDELQFGGDKVFYLSGFIMKKNALEMGLGFGWMPDFLIHQELASGEMVEVDFTGGSRYTFTPKLVSTMERPLGKAGQLFTEFILDEFAKAELSYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQJ9</accession>
    <name>B1KQJ9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetolactate synthase small subunit</fullName>
            <shortName evidence="8">AHAS</shortName>
            <shortName evidence="8">ALS</shortName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1954</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324584.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1954"/>
    <dbReference type="EnsemblBacteria" id="ACA86238">
        <property type="protein sequence ID" value="ACA86238"/>
        <property type="gene ID" value="Swoo_1954"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1954"/>
    <dbReference type="eggNOG" id="COG0440">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055003_1_3_6"/>
    <dbReference type="OMA" id="EPYGIKE"/>
    <dbReference type="OrthoDB" id="1500398at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="18098" checksum="2E545893961D0C05" modified="2008-04-29" version="1">MRRIISVLLENQPGALSRVVGLFSQRGYNIETLTVAPTDDATLSRLNITLFADENVLEQIEKQLHKLIDILKVSNITESEHIERELALVKVKAKGSIREEVKRTADIFRAQIVDITAELYTVQLTGPTAKLDAFISAIGEVTKVVEVSRSGVVGLSRGEKAMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQM0</accession>
    <name>B1KQM0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CreA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324605.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1975"/>
    <dbReference type="EnsemblBacteria" id="ACA86259">
        <property type="protein sequence ID" value="ACA86259"/>
        <property type="gene ID" value="Swoo_1975"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1975"/>
    <dbReference type="eggNOG" id="COG3045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109726_2_0_6"/>
    <dbReference type="OMA" id="QGVTCYV"/>
    <dbReference type="OrthoDB" id="1618795at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010292">
        <property type="entry name" value="Uncharacterised_CreA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37952">
        <property type="entry name" value="PTHR37952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05981">
        <property type="entry name" value="CreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003174">
        <property type="entry name" value="CreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765130" evidence="1">
        <location>
            <begin position="25"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="165" mass="17885" checksum="B72C9E5B4618600F" modified="2008-04-29" version="1" precursor="true">MKNLKLLRTASLVVVMCSGLSACGDDVAKVSLGMFTTKDVLIDAKHDPKIPGVTCHISRVEANLSMADPSDMSISCRQTGPITPAEIASIDKSKNGEIVFKQSLSILFKSLKVRRIYDAENQTLLYLSYSTKETKGSDKHALSTVPLYGTQAWVKPAVPVAEQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQY5</accession>
    <name>B1KQY5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MotA/TolQ/ExbB proton channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3475</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MotA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326075.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3475"/>
    <dbReference type="EnsemblBacteria" id="ACA87741">
        <property type="protein sequence ID" value="ACA87741"/>
        <property type="gene ID" value="Swoo_3475"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3475"/>
    <dbReference type="eggNOG" id="COG1291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079895_1_0_6"/>
    <dbReference type="OMA" id="YAPAWGM"/>
    <dbReference type="OrthoDB" id="897037at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000540">
        <property type="entry name" value="Flag_MotA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01307">
        <property type="entry name" value="MOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="10">
        <location>
            <begin position="98"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="255" mass="27385" checksum="EDF82EA16D1EA977" modified="2008-04-29" version="1" precursor="true">MDLATLIGLIGAFGFILGAMASSGGIGIFIDVASILIVLCGSFFVVMMKYNLKQFFGSIKIAAKAFIFKIDKPDELIEQSVTMADAARKGGFLALEEAEITNSFMQKAVDMLVDGHDGDVVRDALEKDIALTEQRHKLGISIFSTVGDVAPAMGMIGTLVGLVGMLSNMDDPKSIGPAMAIALLTTLYGAMVANMVAIPIAGKLELRMNEEMLNRNLIMDAVLAIQDGQNPRVIEGFLKNYISEKQRQIDTTDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR65</accession>
    <name>B1KR65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-lysine 6-monooxygenase (NADPH)</fullName>
            <ecNumber evidence="4">1.14.13.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0586</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.59" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0586"/>
    <dbReference type="EnsemblBacteria" id="ACA84882">
        <property type="protein sequence ID" value="ACA84882"/>
        <property type="gene ID" value="Swoo_0586"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0586"/>
    <dbReference type="eggNOG" id="COG3486">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020931_0_0_6"/>
    <dbReference type="OMA" id="YHGNTNY"/>
    <dbReference type="UniPathway" id="UPA00246"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047091">
        <property type="term" value="F:L-lysine 6-monooxygenase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802">
        <property type="entry name" value="PTHR42802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="K_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="444" mass="49880" checksum="3125F50B541F2E1C" modified="2008-04-29" version="1">MNKDMKHFDLFGIGIGPFNLSIAALSQGINGLNTAFADAHKSMTWHPGLLLNEARMQTSPLKDMVTAVEPTNPLSFLSYLVNKRKIYAYMAAQMDTISRIEFADYLAWVASRVDNLIFDNPVDAVEFSGDKFLIHSKQGIFTSQHICLGTGKVAHLPACVKPYMGPKCLHASRLALKDRSYQGKTVAVVGGGQTGADVFLNLLQRQWGEPTRVIWISRRPNFQALDEGVFTDQYFTPGYGEIFYGLSEQVKSQEVKHQKLSSDGITSASLNEIYQHLYQERFIKGDKAGDKWNLRPHRTLTKMREQGDKFELTLRNGITNCDESLEVDELILCTGFESQIPSYLAPIKQKLDIDRYGQFNLNREFSVAWDGPQTNKVYAVNAGIHSHGILEPQLSLAAWRSAVIINDMLGHNHFDLSLEESIIDWGQEAPVLNKESIIKHQGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRA7</accession>
    <name>B1KRA7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2OG-Fe(II) oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324660.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2030"/>
    <dbReference type="EnsemblBacteria" id="ACA86314">
        <property type="protein sequence ID" value="ACA86314"/>
        <property type="gene ID" value="Swoo_2030"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2030"/>
    <dbReference type="eggNOG" id="COG3491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_6_3_6"/>
    <dbReference type="OMA" id="DGNSVMR"/>
    <dbReference type="OrthoDB" id="400496at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="147"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="279" mass="31521" checksum="BFC6DED13F41460E" modified="2008-04-29" version="1">MKLETIDYLAPNSAEEFVKSLRETGFGVLSNHPIDKALVEAIYIEWQAFFNTEEKREYLFKPETQDGFFPAEISETAKGHSVKDIKEYYHVYPWGRIPNSLRENILAYYNKANELAQELLGWIESYAPAEVKAKFSISLPQMIENSQKTLLRVLYYPPMSGDEEMGAIRAAAHEDINLITVLPAANEPGLQVQVKDGSWLDVPSDFGNIIINIGDMLQEASGGYYPSTSHRVINPEGADKSKSRISLPLFLHPNPEVVLSDKYTADSYLMERLRELGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD8</accession>
    <name>B1KRD8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324690.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2061"/>
    <dbReference type="EnsemblBacteria" id="ACA86345">
        <property type="protein sequence ID" value="ACA86345"/>
        <property type="gene ID" value="Swoo_2061"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2061"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102556_0_0_6"/>
    <dbReference type="OMA" id="TEVHKFD"/>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027016">
        <property type="entry name" value="UCP029811"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029811">
        <property type="entry name" value="UCP029811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764783" evidence="1">
        <location>
            <begin position="20"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="21"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="191" mass="21036" checksum="3B451AC72FEFCF01" modified="2008-04-29" version="1" precursor="true">MKRTLIALALGTVSFMTSAAPWTIDNQSSEINFITTKKVNVSEVHEFKQFSGSLNEKGEFSLSVELASVWTNIEIRDARMREILFEVEAFPKLELQAKVSPGVLAKMAVGSRSEMQLNAELSFHGKEQTVPMRVSVVKLSEKEVLVLSSQPVIINAEQFGLSSGVEKLREIAGLTSIGHSVPVSFILNLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRJ7</accession>
    <name>B1KRJ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3498</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326095.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3498"/>
    <dbReference type="EnsemblBacteria" id="ACA87762">
        <property type="protein sequence ID" value="ACA87762"/>
        <property type="gene ID" value="Swoo_3498"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3498"/>
    <dbReference type="HOGENOM" id="CLU_2939271_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="60" mass="7289" checksum="0200BE4B1EB81E66" modified="2008-04-29" version="1">MEKLQEKLASQARVFEREKFSSRVRTRHDLEQELEKLKILPFNDGRQSLIKQLEKRLKHV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRQ7</accession>
    <name>RS15_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsO</name>
        <name type="ordered locus">Swoo_3558</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326155.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRQ7"/>
    <dbReference type="SMR" id="B1KRQ7"/>
    <dbReference type="STRING" id="392500.Swoo_3558"/>
    <dbReference type="EnsemblBacteria" id="ACA87822">
        <property type="protein sequence ID" value="ACA87822"/>
        <property type="gene ID" value="Swoo_3558"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3558"/>
    <dbReference type="eggNOG" id="COG0184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148518_0_0_6"/>
    <dbReference type="OMA" id="FKTHVKD"/>
    <dbReference type="OrthoDB" id="1990141at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000143171" description="30S ribosomal protein S15">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <sequence length="89" mass="10377" checksum="7113234C8A748399" modified="2008-04-29" version="1">MSLNAEQTASILAEFGRCENDTGSTEVQVALLTAQINHLQGHFKEHKHDHHSRRGLLRMVNTRRKLLAYLKRTENVRYQELIKKLGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCW9</accession>
    <name>B1KCW9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA topoisomerase type IA zn finger domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322693.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0043"/>
    <dbReference type="EnsemblBacteria" id="ACA84344">
        <property type="protein sequence ID" value="ACA84344"/>
        <property type="gene ID" value="Swoo_0043"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0043"/>
    <dbReference type="eggNOG" id="COG0551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104661_0_0_6"/>
    <dbReference type="OMA" id="HYPECDY"/>
    <dbReference type="OrthoDB" id="1276290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-C4_Topoisom" evidence="1">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="zf-C4_Topoisom" evidence="1">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="zf-C4_Topoisom" evidence="1">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="zf-C4_Topoisom" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20988" checksum="FF05B80AE8611AE9" modified="2008-04-29" version="1">MSKIDQQLFSSHEHALEKEYELCPKCGSELSVKNSKHGGFIGCNNYPNCDYTRPLVQHESIETQVIEGSSCPECGNELAVKSGRFGIFIGCTHYPECRHIEKHDQEEAGNEIPCPLCKKGHVEHRTSRFGKTFYACSGYPKCKFLVNYHPVNEACPECGFGILVERKGAAGGRLECPQKQCKYKRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD77</accession>
    <name>B1KD77_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326245.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3650"/>
    <dbReference type="EnsemblBacteria" id="ACA87912">
        <property type="protein sequence ID" value="ACA87912"/>
        <property type="gene ID" value="Swoo_3650"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3650"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_10_4_6"/>
    <dbReference type="OMA" id="CDPAATG"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766959" evidence="4">
        <location>
            <begin position="20"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="36"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="482" mass="53889" checksum="8E67AF611BE5F407" modified="2008-04-29" version="1" precursor="true">MKKHYPLLLVSLVSFCAFADSKPELQLEKSSNGADQNVLVLLIDDLGWTDLGAYGSQYYESPNIDALASQSRLYTQAYSSSPVCSPSRAALMTGKHPSKLKITTHFPGYKAKSPKLKEPWKADHLALTELTLAEAFKSQGYETFFAGKWHMGGEGYLPTDQGFDINIGGMHRGSPPGGYYDPYKNPNLPNRNKGEHLTKRLTDETIDFLSQKHEKPFFALLSYYGVHTPLQAGPDKLAYFKEKTNTVAGEKAFLIDKGHQSRTQINQVDANYASMIWAVDKSVGRILESLEKQGLDKNTLVVLTSDNGGFSTRHQGDERVTSTANLPLRSGKGWVYEGGVRIPLLIHQPGQQIQSQHDTLTTSADLYPTLANVAGAKIPEGIDGSDIFLLDEEPELAKQRVIVWHHPHYHGSGNKPSAAIRVGDWKLLHFYEQDRVELYNLSNDIAEQVNLEQLEPKRRAHLLALLDEWYRDNDIEQVSLLE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDK4</accession>
    <name>Y2117_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0260 protein Swoo_2117</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_2117</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0260 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324746.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDK4"/>
    <dbReference type="STRING" id="392500.Swoo_2117"/>
    <dbReference type="EnsemblBacteria" id="ACA86401">
        <property type="protein sequence ID" value="ACA86401"/>
        <property type="gene ID" value="Swoo_2117"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2117"/>
    <dbReference type="eggNOG" id="COG2983">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109769_0_1_6"/>
    <dbReference type="OMA" id="GRCCLHK"/>
    <dbReference type="OrthoDB" id="1653862at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00676">
        <property type="entry name" value="UPF0260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008228">
        <property type="entry name" value="UCP006173"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37421">
        <property type="entry name" value="PTHR37421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006173">
        <property type="entry name" value="UCP006173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000131639" description="UPF0260 protein Swoo_2117">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00676"/>
        </source>
    </evidence>
    <sequence length="146" mass="16936" checksum="E4383FCF0F713075" modified="2008-04-29" version="1">MSFWKEKSLAQLDTQEWESLCDGCGKCCLNKLIDDETEELYYTNAACKLLDHQDGHCVHYQERFTFVPSCTQVTVDNVAQLTWLPDSCAYRRLYLGRELPSWHPLITGSKAAMHEAGMSTQNKVKCETKVRYIEDHIVLWPMRDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDK6</accession>
    <name>B1KDK6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S51 dipeptidase E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S51 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324748.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2119"/>
    <dbReference type="EnsemblBacteria" id="ACA86403">
        <property type="protein sequence ID" value="ACA86403"/>
        <property type="gene ID" value="Swoo_2119"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2119"/>
    <dbReference type="eggNOG" id="COG3340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103651_0_0_6"/>
    <dbReference type="OMA" id="GAMIMTP"/>
    <dbReference type="OrthoDB" id="1485646at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="24466" checksum="1DF1BC400F293D6E" modified="2008-04-29" version="1">MKLALLSSPTSSNGIDAIKQILAVQKKKVCKLAYIASGPEPDRRYFSQTQTLYEELGAQMPLFVELESEFDDDILPELFGCDVIHLAGGDTFRFLKGLKRRGLLPKLRQYVEAGGALVGVSAGAMIMTPSIESAFLCGDSNDVELKDLSALELVPFHFMPHLPSELSTPVDFIAELQRKDVEFDEALFESLYLCQDNSALVLIDGELEELGSPLLWTSCVEC</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX1</accession>
    <name>Y3713_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0250 protein Swoo_3713</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_3713</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0250 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326305.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDX1"/>
    <dbReference type="SMR" id="B1KDX1"/>
    <dbReference type="STRING" id="392500.Swoo_3713"/>
    <dbReference type="EnsemblBacteria" id="ACA87973">
        <property type="protein sequence ID" value="ACA87973"/>
        <property type="gene ID" value="Swoo_3713"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3713"/>
    <dbReference type="eggNOG" id="COG2921">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161438_2_1_6"/>
    <dbReference type="OMA" id="MNTKFDE"/>
    <dbReference type="OrthoDB" id="2028648at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00659">
        <property type="entry name" value="UPF0250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007454">
        <property type="entry name" value="UPF0250"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027471">
        <property type="entry name" value="YbeD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38036">
        <property type="entry name" value="PTHR38036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04359">
        <property type="entry name" value="DUF493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117991">
        <property type="entry name" value="SSF117991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000131262" description="UPF0250 protein Swoo_3713">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00659"/>
        </source>
    </evidence>
    <sequence length="88" mass="9725" checksum="CE76D2DDF5BA1BC7" modified="2008-04-29" version="1">MLDTKFDELMEFPCSFPYKVVGDASETLADRVVAVVQKHVPGDYVPSSKVSSKGTYNSITIRVTVQSKEQVESLYIDLAAIEGVKRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE38</accession>
    <name>B1KE38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323371.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0729"/>
    <dbReference type="EnsemblBacteria" id="ACA85024">
        <property type="protein sequence ID" value="ACA85024"/>
        <property type="gene ID" value="Swoo_0729"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0729"/>
    <dbReference type="eggNOG" id="ENOG5033HSH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162057_0_0_6"/>
    <dbReference type="OrthoDB" id="2081007at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="126" mass="13234" checksum="CB5C782939F8746F" modified="2008-04-29" version="1">MAIGNIAASTSINDLSHQTQPQHQTKDLVSSNMAEVPLAKVKLSPAALSLSEREQKLANNTQNSTQVSTQVEAKEDEASGGVKSFAYGALGMDHPDKVDQAEDDSYTAGQFLKAAATVGSVIALFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEJ0</accession>
    <name>B1KEJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS111A/IS1328/IS1533</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0388</name>
        <name evidence="3" type="ordered locus">Swoo_2289</name>
        <name evidence="4" type="ordered locus">Swoo_3496</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908</strain>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323036.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84687">
        <property type="protein sequence ID" value="ACA84687"/>
        <property type="gene ID" value="Swoo_0388"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86568">
        <property type="protein sequence ID" value="ACA86568"/>
        <property type="gene ID" value="Swoo_2289"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87760">
        <property type="protein sequence ID" value="ACA87760"/>
        <property type="gene ID" value="Swoo_3496"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0388"/>
    <dbReference type="KEGG" id="swd:Swoo_2289"/>
    <dbReference type="KEGG" id="swd:Swoo_3496"/>
    <dbReference type="eggNOG" id="COG3547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036902_5_1_6"/>
    <dbReference type="OMA" id="ADMNSHI"/>
    <dbReference type="OrthoDB" id="655500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="11"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="318" mass="35395" checksum="A996CFB1FEE57CA6" modified="2008-04-29" version="1">MNSKTNQNISVGVDTGKFQLDIYIRPLDIFFTVKNDEKGIKDAVNSIKQYTPKRIVIEATGRLEMPFIMACAEANLPFVIANPIHIKRFAGAIGQRAKTDKLDAKLIAHYGEAIKPKLSTLKPSIMQAMSDLVSRRNQILAMQTMEKNRLQILPKDLAMTIKPILTAFKNQIEKIEAKIIKLIESCPDYQAKNIILQSMKGIGKIAAASIISNLPELGYINNKEASSLVGVAPMNKESGRFKGQRKIQGGRHQVRTVLYMAMMSAIQSNPVFKQTYQRLVAAGKPKKVAIIACIRKMVVTLNSMLRDGVMWEAPKAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEQ6</accession>
    <name>B1KEQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3812"/>
    <dbReference type="EnsemblBacteria" id="ACA88071">
        <property type="protein sequence ID" value="ACA88071"/>
        <property type="gene ID" value="Swoo_3812"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3812"/>
    <dbReference type="HOGENOM" id="CLU_3257795_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="42" mass="4774" checksum="E685047D57568237" modified="2008-04-29" version="1">MNTNNKVELIEEALLENVSGGREQAFCVELCFEFCLSICFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER0</accession>
    <name>B1KER0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3816</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326406.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3816"/>
    <dbReference type="EnsemblBacteria" id="ACA88075">
        <property type="protein sequence ID" value="ACA88075"/>
        <property type="gene ID" value="Swoo_3816"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3816"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_3_0_6"/>
    <dbReference type="OMA" id="HSLPPFW"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="10"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="258" mass="28096" checksum="18F6B6040216C45F" modified="2008-04-29" version="1">MNMKALYATAFKSILTKEINRFTRIWVQTLVPPAISMTLYFLIFGNLVGKRIGEMGGVSYMEFIAPGLIMMSVITASYSNVASSFFSAKFQRNLEELIVAPVPHYVIIAGYVGGGVARGLCVGTIVTLVALCFVDISIQHVGLVAITVLLTAILFALGGLINAIFAKSYDDISIVPTFVLTPLTYLGGVFYSLSLLPDFWQGVSQLNPVVYMINVFRYGFLGYADMSIPLSIAVMVGFCVSLWAVAYYLISRGIGLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER9</accession>
    <name>B1KER9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_3825</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326415.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3825"/>
    <dbReference type="EnsemblBacteria" id="ACA88084">
        <property type="protein sequence ID" value="ACA88084"/>
        <property type="gene ID" value="Swoo_3825"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3825"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_8_0_6"/>
    <dbReference type="OMA" id="SICPQKL"/>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="PTHR10110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="9">
        <location>
            <begin position="9"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="680" mass="75624" checksum="DE0C7C1C1A82B4C7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEY1</accession>
    <name>B1KEY1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323479.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0837"/>
    <dbReference type="EnsemblBacteria" id="ACA85132">
        <property type="protein sequence ID" value="ACA85132"/>
        <property type="gene ID" value="Swoo_0837"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0837"/>
    <dbReference type="eggNOG" id="COG3258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043274_0_0_6"/>
    <dbReference type="OMA" id="NCFGCHN"/>
    <dbReference type="OrthoDB" id="1025062at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764363" evidence="1">
        <location>
            <begin position="27"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="488" mass="52570" checksum="ABA554E53BE6C917" modified="2008-04-29" version="1" precursor="true">MSNLYRHLSLASLLVFSSCFSLIASADTWNCPVEKSWLTAPSLPTEVDKSNKDNTSNFCDFYRFSTQAYLYLMSPSLDKPGKRNFQVNANYPVLEYNGDNSPGNSCDKEITGHTLLTSLEQSSISTGQAGGDATIYAQDGNVAYYDVRFNKALCDLTGSATEMQQQGIYNFPGGTTELKFAWKVLSAAEVRSGQFVTQEQLISGKMKTLGLLGMHIAIATEDHPEFVWATYEHKTNSPDCDASAAQKKQAWMFADNTCTQDLPGSAAKGDKCNFNHPKSGLTSPTGTPTNICRVHPYGTAKGDRDAAENLGDILSQNQSLLNQLADSSTPSAMKVLTNYFNLGAIWVSDIAQSSGGVGVPNERGSLRLANSVAETDYQDVNLNSQFASNCFGCHNYQGTAETQKNNITTQALSHTFKDIKIGQGQHIDVTASSYIASNEQAAGICGVTGKSDKEQGTCKGTASFLKWDGNWTNVNRSAGSVCGCGPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF05</accession>
    <name>B1KF05_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inosine/xanthosine triphosphatase</fullName>
            <shortName evidence="4">ITPase/XTPase</shortName>
            <ecNumber evidence="4">3.6.1.73</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Non-canonical purine NTP phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Non-standard purine NTP phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Nucleoside-triphosphate phosphatase</fullName>
            <shortName evidence="4">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_0862</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + ITP = H(+) + IDP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28330"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58280"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.73"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + XTP = H(+) + phosphate + XDP</text>
            <dbReference type="Rhea" id="RHEA:28406"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59884"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.73"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the YjjX NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.73" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323503.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0862"/>
    <dbReference type="EnsemblBacteria" id="ACA85156">
        <property type="protein sequence ID" value="ACA85156"/>
        <property type="gene ID" value="Swoo_0862"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0862"/>
    <dbReference type="eggNOG" id="COG1986">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087417_1_0_6"/>
    <dbReference type="OMA" id="ADYWVGI"/>
    <dbReference type="OrthoDB" id="1597994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103023">
        <property type="term" value="F:ITPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00648">
        <property type="entry name" value="Non_canon_purine_NTPase_YjjX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002786">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026533">
        <property type="entry name" value="NTPase/PRRC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01931">
        <property type="entry name" value="NTPase_I-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00258">
        <property type="entry name" value="TIGR00258"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTPase_I-T" evidence="5">
        <location>
            <begin position="15"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="187" mass="20190" checksum="F875348792C4467B" modified="2008-04-29" version="1">MSKISQLAKIRVIIGSKNPVKVQAAQHALNQLLPNTEIECLGCHAPSGVAEQPMTADETLKGAINRVEHCQSAPDTSEADLFIAIEGGVDNFSYGPATFAYIVISDKQQRLVGRSAILPLPPVVYKALSDGEELGDVMDRLFNTDNIKQKGGAIGLLTQGVATRESIYTQALILTMAPLLNEELYQR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF21</accession>
    <name>PGK_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="1">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pgk</name>
        <name type="ordered locus">Swoo_0878</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323519.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KF21"/>
    <dbReference type="SMR" id="B1KF21"/>
    <dbReference type="STRING" id="392500.Swoo_0878"/>
    <dbReference type="EnsemblBacteria" id="ACA85172">
        <property type="protein sequence ID" value="ACA85172"/>
        <property type="gene ID" value="Swoo_0878"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0878"/>
    <dbReference type="eggNOG" id="COG0126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025427_0_2_6"/>
    <dbReference type="OMA" id="DMIFDIG"/>
    <dbReference type="OrthoDB" id="462069at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000096377" description="Phosphoglycerate kinase">
        <location>
            <begin position="1"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="345"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <sequence length="391" mass="40624" checksum="92FED43FA39A555A" modified="2008-04-29" version="1">MAIINMSELDLQGKRVLIREDLNVPVSEGVVTSDARLRAALPSIKLALEKGAAVMVMSHLGRPTEGEFNSEFSLQPVVDYLTKALSCPVRLAKDYLDGVEANVGEVVVFENVRFNVGEKKNDEALAKKLAALCDVYVMDAFGTAHRAQASTHGVGLHAPIACAGPLLAGELEALGKAMDNPARPLVAIVGGSKVSTKLTVLESLSKIVDQLVVGGGIANTFIAAAGHEVGKSLYEADLIDEAKRLAANAQSRGGDIPVPTDVVVAGEFSPTAAATLKGVSQVSADEMIFDIGPDSSEALAEILKNAGTIVWNGPVGVFEFDQFGEGTKRIAAAIADSSAFSIAGGGDTLAAVDKYGIADKVSYISTGGGAFLEFLEGKELPAVAMLESRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF24</accession>
    <name>B1KF24_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323522.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0881"/>
    <dbReference type="EnsemblBacteria" id="ACA85175">
        <property type="protein sequence ID" value="ACA85175"/>
        <property type="gene ID" value="Swoo_0881"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0881"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090658_0_0_6"/>
    <dbReference type="OMA" id="FPWQSIA"/>
    <dbReference type="OrthoDB" id="1862657at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="27832" checksum="D5C776CA0E55DC41" modified="2008-04-29" version="1">MQIGSCWFDINSKTLSNLTNDTSWKMPATEFSVLEALVLQRGQVLSREELLSSMPEDKQEQAQLILAIERVKFYLGVEYAELLETVDKQGYLLHCAVKSKARSTSSVPFGSISAKDYFIFIVLLLGLLCLINSLFAPSMKINSVTEQVITSHSSKLSLYPVFSSEKLKREYQPQTEFLTQSLKDCTKVPWQDLFLSVSTENNLISMVLKRQLDAGVEMKNLKVAPLDEGWQFITQEWLIKVGVCSE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF50</accession>
    <name>IHFB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integration host factor subunit beta</fullName>
            <shortName evidence="1">IHF-beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ihfB</name>
        <name evidence="1" type="synonym">himD</name>
        <name type="ordered locus">Swoo_2312</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324933.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KF50"/>
    <dbReference type="SMR" id="B1KF50"/>
    <dbReference type="STRING" id="392500.Swoo_2312"/>
    <dbReference type="EnsemblBacteria" id="ACA86591">
        <property type="protein sequence ID" value="ACA86591"/>
        <property type="gene ID" value="Swoo_2312"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2312"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_2_0_6"/>
    <dbReference type="OMA" id="RDRVNIY"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00381">
        <property type="entry name" value="IHF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005685">
        <property type="entry name" value="IHF_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00988">
        <property type="entry name" value="hip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0810">Translation regulation</keyword>
    <feature type="chain" id="PRO_1000122243" description="Integration host factor subunit beta">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="95" mass="10703" checksum="DDA45A28113CAC0F" modified="2008-04-29" version="1">MTKSELIEKLAMRQSQLSAKEVESAIKEMLEQMAQTLEGGDRIEIRGFGSFSLHFRAPRTGRNPKTGTSVELDGKYVPHFKPGKELRERVDAINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF80</accession>
    <name>B1KF80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324963.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2342"/>
    <dbReference type="EnsemblBacteria" id="ACA86621">
        <property type="protein sequence ID" value="ACA86621"/>
        <property type="gene ID" value="Swoo_2342"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2342"/>
    <dbReference type="eggNOG" id="COG5528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127159_0_0_6"/>
    <dbReference type="OMA" id="LPVVWMQ"/>
    <dbReference type="OrthoDB" id="1724614at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018729">
        <property type="entry name" value="DUF2269_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10027">
        <property type="entry name" value="DUF2269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="157" mass="17972" checksum="5DA5B95CAA0577B7" modified="2008-04-29" version="1">MEYYLVVKYIHIIAAVVVTGTGTGIAFFMFMANRSNNPQAIYITTKHVILGDWFFTTPAVITQIVTGILLMNMLGYSYSSAWFYWVFGLFSFIGLCWLPVLKIQYQLRELAKISVELNQVTSEFKSLMKIWTLLGIPAFIAILGIFWLMVFKPFPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFC8</accession>
    <name>B1KFC8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermidine/putrescine-binding periplasmic protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325011.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2390"/>
    <dbReference type="EnsemblBacteria" id="ACA86669">
        <property type="protein sequence ID" value="ACA86669"/>
        <property type="gene ID" value="Swoo_2390"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2390"/>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_775889_0_0_6"/>
    <dbReference type="OMA" id="YDWVTGF"/>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766531" evidence="1">
        <location>
            <begin position="25"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="373" mass="42666" checksum="D385B098E9CE9142" modified="2008-04-29" version="1" precursor="true">MKKYIGFSLIIAISSLLVSPFSISDQSSEAQVLRVLTWEGYVTDSDLSHVNQLLLEQGYDYRVEVISPYAEGAEQMYNLIRGKECDITFLTLFFIKMKKEQTAKLLQPVNIDSPRLTNYQHLYPNLARLKMGIDRDGLPLYIPWGGGIYGFYIDNDRVPVSLRPYSVKALWQPEWRHKFSLNGAQEWYNIGLTLMSQGESPFYLYEEFQKENRSGVMVKSAPDGAFQTQLTALYDAAGSFWTDAPTFNDELLIVSSWGPEIHAENMRGGNWELIDFEEGHMAWLDTINFVKGLSGRKLEAAEIFANYFIGKEVQNRISNELSMVPASKTVPVNTILGDPDKILNENMFVPPYDQRSYGLMKKMLERAKEQRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFD3</accession>
    <name>B1KFD3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2395</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325016.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2395"/>
    <dbReference type="EnsemblBacteria" id="ACA86674">
        <property type="protein sequence ID" value="ACA86674"/>
        <property type="gene ID" value="Swoo_2395"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2395"/>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030140_1_2_6"/>
    <dbReference type="OMA" id="SDLWYDK"/>
    <dbReference type="OrthoDB" id="944149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="5">
        <location>
            <begin position="127"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="478" mass="52767" checksum="517BE616243B7892" modified="2008-04-29" version="1">MSADKHLQSWQERFEMAEAMQPLLGKLYRNQGVEVVLYGKPLLNASTIEIIKSHRLVRKHVGYKLRLRESFPFVEALSKLAVKQCKVDIGKLAIKYWRENDDASGIEAYMSQELATAIDHDDQEKPRDVVLYGFGRIGRLLARLLIERTGVSNKLRLRAIVLRGGRKGDLEKRASLLRRDSVHGPFNGSVEVDEENNAIIANGTYIQVIYANSPDAIDYTSFDINDALVVDNTGIWKDEDGLGLHLKSKGATKVLLTAPAKGSIKNIVYGVNESDILAEDTIVSAASCTTNAITPVLKAINDKYGIENGHVETIHSYTNDQNLIDNYHSADRRGRSAPLNMVITETGAAKAVSKALPVLEGKLTGNAIRVPTPNVSMAIISLNLNGETNKEEINDYLRNIALNSDLQNQVDFTESTEIVSSDLVGSRYAGVVDSQATIADGKRTILYVWYDNEFGYSCQVVGVMQKMLGLNYQSLPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFJ6</accession>
    <name>B1KFJ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenylalanine/histidine ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326501.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3913"/>
    <dbReference type="EnsemblBacteria" id="ACA88171">
        <property type="protein sequence ID" value="ACA88171"/>
        <property type="gene ID" value="Swoo_3913"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3913"/>
    <dbReference type="eggNOG" id="COG2986">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014801_4_2_6"/>
    <dbReference type="OMA" id="FEANIFG"/>
    <dbReference type="OrthoDB" id="715502at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016841">
        <property type="term" value="F:ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764386" evidence="1">
        <location>
            <begin position="25"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="552" mass="60263" checksum="F24E1867FB66B604" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFV2</accession>
    <name>B1KFV2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LprI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323615.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0975"/>
    <dbReference type="EnsemblBacteria" id="ACA85268">
        <property type="protein sequence ID" value="ACA85268"/>
        <property type="gene ID" value="Swoo_0975"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0975"/>
    <dbReference type="HOGENOM" id="CLU_1863808_0_0_6"/>
    <dbReference type="OrthoDB" id="1517357at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009739">
        <property type="entry name" value="LprI_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07007">
        <property type="entry name" value="LprI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764416" description="LprI domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="LprI" evidence="2">
        <location>
            <begin position="31"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15950" checksum="C13982A099FCB815" modified="2008-04-29" version="1" precursor="true">MKKYLAPLIFLMFVNMAYGQQTFIGCDELWQTMSEMVQCQMKANQAKEQEISALINTIQSSFKVKKRSLSVLKSQEHWVNYVESECRSRMISGALSGTSNAARYHICRNEKLSSRLDELQKYHYCDDNGCPERYKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY0</accession>
    <name>B1KFY0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2409</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325029.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2409"/>
    <dbReference type="EnsemblBacteria" id="ACA86687">
        <property type="protein sequence ID" value="ACA86687"/>
        <property type="gene ID" value="Swoo_2409"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2409"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_9_6"/>
    <dbReference type="OMA" id="ATILIAH"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="29"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="469"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="554" mass="61899" checksum="28FD6090B2E892FC" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG61</accession>
    <name>SYT_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="1">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thrS</name>
        <name type="ordered locus">Swoo_2491</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325109.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KG61"/>
    <dbReference type="SMR" id="B1KG61"/>
    <dbReference type="STRING" id="392500.Swoo_2491"/>
    <dbReference type="EnsemblBacteria" id="ACA86768">
        <property type="protein sequence ID" value="ACA86768"/>
        <property type="gene ID" value="Swoo_2491"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2491"/>
    <dbReference type="eggNOG" id="COG0441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_0_1_6"/>
    <dbReference type="OMA" id="FYYDFAY"/>
    <dbReference type="OrthoDB" id="900765at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000098613" description="Threonine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Catalytic" evidence="1">
        <location>
            <begin position="243"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="511"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01228"/>
        </source>
    </evidence>
    <sequence length="642" mass="73445" checksum="0A5930DE626B4DE6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG63</accession>
    <name>B1KG63_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2493"/>
    <dbReference type="EnsemblBacteria" id="ACA86770">
        <property type="protein sequence ID" value="ACA86770"/>
        <property type="gene ID" value="Swoo_2493"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2493"/>
    <dbReference type="eggNOG" id="ENOG50331EB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_189936_2_0_6"/>
    <dbReference type="OMA" id="QYIEDCP"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025990">
        <property type="entry name" value="Cys_rich_CPXCG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017143">
        <property type="entry name" value="UCP037225"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14255">
        <property type="entry name" value="Cys_rich_CPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037225">
        <property type="entry name" value="UCP037225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="66" mass="7645" checksum="03C2F7EA305C3D51" modified="2008-04-29" version="1">MKFTTQTISCPHCGHHQHIDVDGTSGDQDYYDDCRICCNPIHLRIHLDEARHTLELYVDAGDEQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG76</accession>
    <name>B1KG76_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH dehydrogenase (Quinone)</fullName>
            <ecNumber evidence="4">1.6.5.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3956</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.5.11" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326543.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3956"/>
    <dbReference type="EnsemblBacteria" id="ACA88213">
        <property type="protein sequence ID" value="ACA88213"/>
        <property type="gene ID" value="Swoo_3956"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3956"/>
    <dbReference type="eggNOG" id="COG0651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030481_0_0_6"/>
    <dbReference type="OMA" id="KIPYFAF"/>
    <dbReference type="OrthoDB" id="1887859at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="3">
        <location>
            <begin position="112"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="566" mass="61886" checksum="FF35A24C76B0955F" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG97</accession>
    <name>B1KG97_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3977</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326564.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3977"/>
    <dbReference type="EnsemblBacteria" id="ACA88234">
        <property type="protein sequence ID" value="ACA88234"/>
        <property type="gene ID" value="Swoo_3977"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3977"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_27_6"/>
    <dbReference type="OMA" id="MHKELSR"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="160"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="220"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="47916" checksum="294666019FA472BF" modified="2008-04-29" version="1" precursor="true">MKKLIASLVLVVLASIASLGWSISEFANLQSSDTQELTTVEHLRALKLIGAALAKSLDNDQADGSFIDSWNLSNSEKLSLIAETEFILPSSLQSQFNTEASLLLESAEGISLHYRLPNTGQVLNISTKLVTSTDDSLSLNKLYTMIFYVGVVAILFLWVSPLIRQLLNLSQTAKAFGMGELGQRIKLNKTSYIGSIETEFNRMADRIQQLVDDNKLLSRAVSHDLKTPIARLRFGIEVLEENQNEQLREKYFQRLNRDLDTMEELVMTLLSYARLDQANIQPEIQPIELNAWLEQKLAKHNSAACSVSFVPLPQSVIVNSDPKYLSMQVSNLLNNAQGFGQSKVQVLLVVEADQVWIHIDDDGPGIDAEEAEQIIKPFVRGKQSRDNSGHGMGLAIVSRIGLWMGSTLAIGHAPTLGGARMSLRFTSFKGSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGA8</accession>
    <name>B1KGA8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 10">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8 10">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ung</name>
        <name evidence="12" type="ordered locus">Swoo_3988</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8 10">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8 10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326574.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3988"/>
    <dbReference type="EnsemblBacteria" id="ACA88245">
        <property type="protein sequence ID" value="ACA88245"/>
        <property type="gene ID" value="Swoo_3988"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3988"/>
    <dbReference type="eggNOG" id="COG0692">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032162_3_0_6"/>
    <dbReference type="OMA" id="PDNGYLM"/>
    <dbReference type="OrthoDB" id="1260295at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="49"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA88245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="24589" checksum="7CBF8ADA0B8E6B8A" modified="2008-04-29" version="1">MTRVKDWDGFLAAEREQDYYRALQAFVLAERANGKAVFPPEAEVFTAFNLTPLDKVRVVIIGQDPYHGPDQAHGLCFSVKHGIKIPPSLVNMYKELATDIPGFTAPEHGHLSSWAEQGVLMLNTVLTVEQGKAHSHAKSGWETFTGHAMELLNQQTSPIVFILWGAHAIKKGKVITGKQHHILSGPHPSPLSAYRGFFGCQHFSKTNQILTSLGTPEINWQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGC7</accession>
    <name>B1KGC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326593.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4008"/>
    <dbReference type="EnsemblBacteria" id="ACA88264">
        <property type="protein sequence ID" value="ACA88264"/>
        <property type="gene ID" value="Swoo_4008"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4008"/>
    <dbReference type="eggNOG" id="COG4558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_6_0_6"/>
    <dbReference type="OMA" id="PNVGYMR"/>
    <dbReference type="OrthoDB" id="1473468at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764437" evidence="1">
        <location>
            <begin position="32"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="42"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="304" mass="32392" checksum="7AE2B98806C5900E" modified="2008-04-29" version="1" precursor="true">MLNKTKLNGFIPPKIVATTLLWAGLSAGVSAHDAEHHNEVTRLISAGAGMTELVIALDAGDELVAVDSTSQLPETFSSVEKLGYHRMLSAEGILALEPDLVLGSDAMGPETTLEVLEGADIKVVKLAGAETAEQLLSNINRLGELLDRQKQAETLKFRVAQSFDSIKQKRVSITGSDKVPSILFMLLQDDRPVRVGGEGTAADTIIKLAGGKNIADFVGYKSLSQEGVLALQPDLILISSRSESEEQSAPDKVLKQMPLLIHTPAGEHKMIHSLKAQALLGGLGLSSLEAADKLASSLIEIQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGL4</accession>
    <name>B1KGL4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323688.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1049"/>
    <dbReference type="EnsemblBacteria" id="ACA85342">
        <property type="protein sequence ID" value="ACA85342"/>
        <property type="gene ID" value="Swoo_1049"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1049"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_1_2_6"/>
    <dbReference type="OMA" id="KRMFGHF"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="6"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="27005" checksum="E45D96C8C4B8D60B" modified="2008-04-29" version="1">MESKRARLDRFISQHLKINRKNVRLMLAKGQVRVDGELARDIDLIVDEFSHICVNDEVIQAKQASYIMLHKPVGVVSATVDDKHKTVIELLKCDDRNSLHIVGRLDLNTSGLLLLTNDGRWSKQLMDPEYKVGKLYRVELQNPLTVEYISAFAKGMYFEFEDITTLPAELEIVDSHTALVTLYEGRYHQIKRMFGRFRNPVVGLHRISVGQIVLDKTLASGQSRPLTPEEIKHKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGM8</accession>
    <name>B1KGM8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KAP P-loop domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323702.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1063"/>
    <dbReference type="EnsemblBacteria" id="ACA85356">
        <property type="protein sequence ID" value="ACA85356"/>
        <property type="gene ID" value="Swoo_1063"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1063"/>
    <dbReference type="eggNOG" id="COG4928">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039725_3_1_6"/>
    <dbReference type="OMA" id="IYFNAWE"/>
    <dbReference type="OrthoDB" id="1668340at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011646">
        <property type="entry name" value="KAP_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07693">
        <property type="entry name" value="KAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KAP NTPase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="467" mass="53487" checksum="0FC67D1067DE3FB0" modified="2008-04-29" version="1">MEFKSHKVIVDSENPFKNDRLNRQPHVDNFSTLLENISSPIVLSVNAPWGQGKTTFLEMLHAQLAIKEHNSIYFSAWETDFASDPLQAFLGEINESIETLINGDEEKNKAWETTKKAGSHILRKGLPALIKVGTAGILDAEKIIEDESSKVMEGLTKDFLSEYTKNKEAISQFKSGVSKVLSNEGSPSTRLFIFIDELDRCRPTYAIELLERIKHLLDIEGLVFVLAMDKVQLSHSVKGIYGDKFEAIGYLRRFIDIEYTLPESDLDAFIDQLYINFGFNDFFQKRMQYQEFQYDKDHLKDTFKLLANAKKLSLREVEQLFAKINLVIQSTAENIYLYPSLLAFLIIAKEYHYDNYNDYINKGDTPEKLISDLYAMIPLSELLGSHSCALVESYLIGAKYDDYNNTVGDSLKRHEDIENDESSSKEQKRYSDKIVQISTSFSGFRNSISLDSLKQRIEMVESFQFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH47</accession>
    <name>B1KH47_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326688.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4103"/>
    <dbReference type="ESTHER" id="9gamm-a0j0x6">
        <property type="family name" value="Est-OsmC"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88359">
        <property type="protein sequence ID" value="ACA88359"/>
        <property type="gene ID" value="Swoo_4103"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4103"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_681299_0_0_6"/>
    <dbReference type="OMA" id="AHCFTCS"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="45"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="402" mass="44045" checksum="0E3A52811430F140" modified="2008-04-29" version="1">MKEKIEFPSNGITLAGLLERPEGEVGAYALFAHCFTCGKDIAAASRISRALVQKGIAVLRFDFTGLGNSDGDFANTNFSSNLDDLKAAADFLREQYDAPQLLIGHSLGGSAVLAIANDIPECKAVVTIAAPANAEHVVHNFSSAIDEINSQGLAAVNLGPRQFTIKKHFLEDLDHHAKQAFSLDKKALLVMHSPVDDAVSIAQAEKIYTQAKHPKSFVSLDTADHLLTSKADADYVASVVASWSGRYLDFSIAAKRAHKVTEGHLRVEEKDHKFTQTIISDSHVWLADEPLKVGGKNLGPDPYEHLLAALGACTSMTMRMYADRKKWPLEDIKIDLSHSRTYIKDCEDCETGNTQLDTLSREIELVGALTEEQRQSLLTISEKCPVHKTLHSKLKVTTELKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH50</accession>
    <name>B1KH50_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_4106</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326691.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4106"/>
    <dbReference type="EnsemblBacteria" id="ACA88362">
        <property type="protein sequence ID" value="ACA88362"/>
        <property type="gene ID" value="Swoo_4106"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4106"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="FNWPGHP"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="243" mass="26868" checksum="760562AD4B7DE2C1" modified="2008-04-29" version="1">MIAPEQLVQLSGITKTFVDGDQRHTVLNRLDLTLSQGETIALTGASGSGKSTLLNLIAGFERDDAHSAVTNSTSLTAYSSDTSSGTLTLLGQDTTRWKDRDWSQFRQTSLGVVFQQFNLLTPLNVKDNIAFPLRLNGQDWNPWCTHLANTLGLNELLNRHVESLSGGQQQRVAIARALAHKPPLILADEPTGNLDQTASMEVMRLLCELAGEHKTSILMVTHSLECANFMLRRWHLDRGKIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHB1</accession>
    <name>B1KHB1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323765.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1126"/>
    <dbReference type="EnsemblBacteria" id="ACA85419">
        <property type="protein sequence ID" value="ACA85419"/>
        <property type="gene ID" value="Swoo_1126"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1126"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068621_1_0_6"/>
    <dbReference type="OMA" id="RMMKRVI"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767057" evidence="1">
        <location>
            <begin position="20"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="140"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="335" mass="38011" checksum="21858A9F6156D634" modified="2008-04-29" version="1" precursor="true">MNRYILVFTLVIASFGAQASNLINDERIKKQTDCFSKIFSDYDSWRGFIEKKYRKRAKSDTKVEQKLAQFDVIFGKEKFNYFKDKLACRNFEYSVDGQAVYGYVIKPKLAKNDLPVLIYNRGGNGGFGGVVLGAMIQNLFPIAEKGFVIIGSQYRGTFTKDDSLDQFGGKDVDDVIALLDYIPSIEGADHNRIGMYGASRGGMQTHLATKRIKNIKAIATLAGPSDLLKGLTYRPKMEKVFKHRIPDYEKNKVSELEKRSVLSWVDELSADVPILLLHGTNDKRVSVNHSIDLADALSKHKIPHKLVLYPEDNHGLMQNKEKANIELVNWFREYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHC6</accession>
    <name>B1KHC6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor jumonji jmjC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323780.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1141"/>
    <dbReference type="EnsemblBacteria" id="ACA85434">
        <property type="protein sequence ID" value="ACA85434"/>
        <property type="gene ID" value="Swoo_1141"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1141"/>
    <dbReference type="eggNOG" id="COG2850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_825764_0_0_6"/>
    <dbReference type="OMA" id="YPALWWH"/>
    <dbReference type="OrthoDB" id="1885303at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="98"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="338" mass="38080" checksum="665ACFA3FC3B6683" modified="2008-04-29" version="1">MNTGNTQVRAITVSNIDELLSQIETADEPLVFKGLCSDWPLVKAGLESNQEAMKYLASFYQGMPVTAYQLAPQHKGRVFYNSEFNGFNYQAGRLDLKQLFSHLVQEANRPTPAGIYMGSTDINQCLPGLGAENSLMLGDISPLTNIWLGNQTHVAAHFDFPHNLACNAVGHRRFTLFPPEQVSNLYIGPMEFSPGGQDISLIDLQQPDLEKFPKFSTALAASQTAELDPGDILFIPSMWWHHVSSLDEFNVLITHWWRDTPAYLGRPNNALLHSMLSLRSLPKAQRLAWKALFDHYIFEHDDQPQDHIPPHAQGCLHKPLDELNARKLRADLTNKLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHD2</accession>
    <name>B1KHD2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Beta-glucosidase</fullName>
            <ecNumber evidence="3 11">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1147</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3 11"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323786.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1147"/>
    <dbReference type="CAZy" id="GH1">
        <property type="family name" value="Glycoside Hydrolase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85440">
        <property type="protein sequence ID" value="ACA85440"/>
        <property type="gene ID" value="Swoo_1147"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1147"/>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001859_1_3_6"/>
    <dbReference type="OMA" id="WHVCEHG"/>
    <dbReference type="OrthoDB" id="654705at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="405"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 10">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="446" mass="50799" checksum="F5A3326D043F34C9" modified="2008-04-29" version="1">MKISLPEASRLNQKEFTYGVATASFQIEGGYDSRLPCIWDTFCSTQGKIRDGSDGKSACEHLKLWKEDIELIDSLNVDAYRLSLSWGRVINQDGSVNSEGIDFYIQLLDALKRKKIKAFVTLYHWDLPQHIEDNGGWLNRETAFLFQDYADKVSQILGDRVYSYATLNEPFCSSYLGYEAGIHAPGLAQVSYGRQAAHHLLLAHGLAMQVLQKNAPHSLNGIVLNFTPCYPVSDSLQDKKAAALADEYFNQWYIKPLFDGRYPDIMGSLEDKDKPVILAGDMDILTQPLDFLGVNFYTRNRYQHCPEQRFKEITMPDVPRTDIGWEIYPQAFTDLLISLDKSYQLPPIYITENGAAMDDKLIAQSVNDLDRVQYYQGHLEALDKAIEAGVNIQGYFAWSLMDNFEWAEGYLKRFGLVYVDYNTQVRTIKASGLAYRDFITARHTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHD3</accession>
    <name>B1KHD3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glucose/galactose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_1148</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Intake of glucose and galactose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323787.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1148"/>
    <dbReference type="EnsemblBacteria" id="ACA85441">
        <property type="protein sequence ID" value="ACA85441"/>
        <property type="gene ID" value="Swoo_1148"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1148"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028452_2_2_6"/>
    <dbReference type="OMA" id="GYRWTFI"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005354">
        <property type="term" value="F:galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005355">
        <property type="term" value="F:glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005964">
        <property type="entry name" value="Glc/Gal_transptr_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01272">
        <property type="entry name" value="gluP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="13">
        <location>
            <begin position="23"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="428" mass="45561" checksum="B2DD08B33AFC624B" modified="2008-04-29" version="1">MASTSVLNEQSQSAHQSGDFRFALVALTSLFFMWGFITCLNDILIPYLKNMFDLNYTQAMLVQFCFFGAYFIVSIPAGSLVGKIGYQKGIVTGLAIACLGCLLFYPSASFASYWMFLVAFFVLASGITILQVAANPYVSVLGPANTASSRLTLTQAFNSLGTTVAPFFGSWLILSTSEHGGTNSEVLNDAAYQASTVQVPYLILAGTLILIAALFLRLKLPLLGMKKSSSLPEKPGVHSISAWHYPHLVLGAVGIFVYVGAEVSIGSFLISFLGQEEIAGLSHAEAANYIAYYFGGAMVGRFLGAAVMQKIKAGKVLAFNAVLACVLIVFAIFSTGSLAMWALLLVGLCNSIMFPTIFSLALQDLGQFTSQGSGILCLAIVGGAIIPLLQGGLADIFGIQLAFALPLLCYGFIAYYGMKGCDAKRPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHV9</accession>
    <name>B1KHV9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326766.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4181"/>
    <dbReference type="EnsemblBacteria" id="ACA88437">
        <property type="protein sequence ID" value="ACA88437"/>
        <property type="gene ID" value="Swoo_4181"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4181"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_15_3_6"/>
    <dbReference type="OMA" id="VFIWGFT"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="11"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="152"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="297" mass="32208" checksum="257A2BB6352D115C" modified="2008-04-29" version="1">MTQAESNRQSGLLELHIAVLLFGGTALFSKLIPLGALDITLLRCLIAATALALLVKASKSRLRLDSSKDYFIAIGLGIVVSLHWVTYFASMQLSSVAIGMIAFFTYPVMTVLVEPFFTGSPIKKVDIISGLVVLTGVILLIPEANLGNDVTLGIAIGILSAIFFTVRNLLHKRYFSAYSGSKAMFYQTAVAVIFLAPWHTIELGQIEQNVWWMILLLGVVFTAAPHALFTAALRHLSAKTVSLVSCLQPFYGAMLALLFLGETLDLKTTIGGFLVVATSIFETQQSRKQPKVAPSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHX3</accession>
    <name>B1KHX3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type I secretion outer membrane protein, TolC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326780.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4195"/>
    <dbReference type="EnsemblBacteria" id="ACA88451">
        <property type="protein sequence ID" value="ACA88451"/>
        <property type="gene ID" value="Swoo_4195"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4195"/>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012817_0_2_6"/>
    <dbReference type="OMA" id="YNAKQQL"/>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010130">
        <property type="entry name" value="T1SS_OMP_TolC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01844">
        <property type="entry name" value="type_I_sec_TolC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766631" evidence="3">
        <location>
            <begin position="24"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="443" mass="48782" checksum="D3123FF2694CE22D" modified="2008-04-29" version="1" precursor="true">MKFKIRTICAALTLAATSSAVQADDLLQIYQQALTSDPVALQAQAQRDSLYEQIEENRAPLLPTISASVGYGKSWRDEQTLPQTDSSGLKAAISLNQVIYDHSAWVGLSLAELAASQADSIYASTLQTLIIRVTTAYFDVLSAKDNFEFKGSEKRAIERQLEQTKQRFAVGLTAITDVHEAQAQYDLARASEILAENQLINSYEALREITGIDHKSINILDTNRFTAVTPTPTLSSDWLKMAETNSVDLMTNRIGKDIAQETITLYKAGHMPSLSLNAGYDTNIEQENQNGSQNDFDNANVALQLSIPIFEGFKVSSKVNQAQYQFVEASEKMEQTYRKVVKDVRNNFNNVGASISSIKAYEQSVVSSESALSATQAGFEVGTRTIVDVLNRTRDLYDSKRQLSDARYSYIKSILALKQAAGTLNEDDVIAINNGLIAQTTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHZ8</accession>
    <name>B1KHZ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323822.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85476">
        <property type="protein sequence ID" value="ACA85476"/>
        <property type="gene ID" value="Swoo_1183"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1183"/>
    <dbReference type="eggNOG" id="ENOG5032BY0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_536253_0_0_6"/>
    <dbReference type="OrthoDB" id="637640at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="508" mass="58431" checksum="97CE8F90EFD48B28" modified="2008-04-29" version="1">MSRVTLRKIFGSEMAQEDPDFLSYAMPRNDYLLPLSDEDNKAIILNAARGSGKSGLLISLSEHLKGTSNTKIISLDYRDMVFPVGKISVNESINYWKNTILSKVVAEIGTSKGWAFIDDDICAVELSENYGVKSKNLLTSILSRLKFKSSPIERCQFDSNITIKQLSRIISASSIKYWIMLDEMDDIYDNGDEINLLIGLLQVVAYLGVRIPNIWVRVTIRPHILTLLRTTNGTIQKLNEYELNLSWSKEQIKEVLARRLDFYQRNNSNEDQLELTLSEPNALSDKSIETSKLISTYFEDFDMGFSVGSTSNYRAFGTLCFYRPRWLIEYCKEVRKITTESKRSNLYHYKRAFLPFGNRRIQFISGEFSKTIHYIHAALNALIALDVSGFGTSKKFRSVIVNQIIKTGIVQAEEHEYHRVALDIAKNLYITEFVRGKVRVDGAGGYHRFYYYNDRPDLLSSWQQDKNIHWEIHPTFQRAFDLEDSQVYKISEDVKIIGNKHQDKEGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI56</accession>
    <name>B1KI56_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Signal peptidase I</fullName>
            <ecNumber evidence="4 8">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1242</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="4 8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323880.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1242"/>
    <dbReference type="MEROPS" id="S26.001"/>
    <dbReference type="EnsemblBacteria" id="ACA85534">
        <property type="protein sequence ID" value="ACA85534"/>
        <property type="gene ID" value="Swoo_1242"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1242"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_1_1_6"/>
    <dbReference type="OMA" id="SDSRFWG"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019766">
        <property type="entry name" value="Sign_pep_all-beta_subdom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S26" evidence="10">
        <location>
            <begin position="60"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="34356" checksum="B767E9582AF8E7D0" modified="2008-04-29" version="1">MAAYFSLILVLVTLCSGLVWMADALLLAPKRREKLAMAQAADANISEEIAEKITREPALVETSRSIFPVIAFVLILRSFIYEPFQIPSGSMMPTLLVGDFILVEKFTYGLKDPVWRSQLVDNGKPERGDVAVFKYPVDPKIDYIKRVIGLPGDRIVYRNKQLYIQPACAEGAETCPELKQVPRVSVNQGEFTHNGTPLLRYTEKLGDVSHDILIDPSRPEPLSYYFREGNLPVGEFIVPEGQYLMMGDNRDNSTDSRFWGFVPEENLVGKAVAIWISFEFERSKADFLPSWIPTGVRFERVGGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI62</accession>
    <name>B1KI62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323886.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1248"/>
    <dbReference type="CAZy" id="GH110">
        <property type="family name" value="Glycoside Hydrolase Family 110"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85540">
        <property type="protein sequence ID" value="ACA85540"/>
        <property type="gene ID" value="Swoo_1248"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1248"/>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017693_0_0_6"/>
    <dbReference type="OrthoDB" id="1217730at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767370" evidence="1">
        <location>
            <begin position="23"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="610" mass="69119" checksum="3625E8737EB08DC3" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI98</accession>
    <name>B1KI98_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamine pyrophosphate protein TPP binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325289.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2673"/>
    <dbReference type="EnsemblBacteria" id="ACA86949">
        <property type="protein sequence ID" value="ACA86949"/>
        <property type="gene ID" value="Swoo_2673"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2673"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_3_0_6"/>
    <dbReference type="OMA" id="AANWYAR"/>
    <dbReference type="OrthoDB" id="351701at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="7"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="649" mass="70709" checksum="E824DF03CD51819B" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE9</accession>
    <name>B1KIE9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_2724</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325337.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2724"/>
    <dbReference type="EnsemblBacteria" id="ACA87000">
        <property type="protein sequence ID" value="ACA87000"/>
        <property type="gene ID" value="Swoo_2724"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2724"/>
    <dbReference type="eggNOG" id="COG0591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_22_0_6"/>
    <dbReference type="OMA" id="LEVWDRG"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="787"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="1022"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="9">
        <location>
            <position position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA87000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1140" mass="124950" checksum="4E0BF8BE9E4172DA" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIS0</accession>
    <name>B1KIS0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323914.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1276"/>
    <dbReference type="EnsemblBacteria" id="ACA85568">
        <property type="protein sequence ID" value="ACA85568"/>
        <property type="gene ID" value="Swoo_1276"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1276"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059002_0_0_6"/>
    <dbReference type="OMA" id="RTICNDK"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="364" mass="41151" checksum="387051CB3395A3D7" modified="2008-04-29" version="1">MAQIRVWVVDDDPDYCELISEVLSDDYQVTLFNDANSYRTALELETPELILMDINLPDVSGIELCQELMNSGKDVAVIFVSGMNTLEERLRAYEVSAVDFIAKPFELKELQAKVQAVASYQAKKQSLVQAESMSRNMAFQSMTESSQYGAVLQFFRQCFLCNDYQSLADAFFELMQQLNLSTCLEIRDMEVHYFAPQNAEISPIEANILELLDKHGRLYDFGSRTICNDKHVSFLIKNMPMDDEVLYGRLRDVIAVIVEGLEARVMDIGRQKTLEHVFKEIQGLLGNISGAIVEHDQKFSAALTGVTTEIRSSFHVLDMTEEQEDYFASLVERNLKEASSAGDAFYRLQGSLKTVRNVVESSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIV4</accession>
    <name>B1KIV4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323948.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1310"/>
    <dbReference type="EnsemblBacteria" id="ACA85602">
        <property type="protein sequence ID" value="ACA85602"/>
        <property type="gene ID" value="Swoo_1310"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1310"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_6"/>
    <dbReference type="OMA" id="QETQRID"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="164"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="223"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="497" mass="53584" checksum="304B80D0471BB566" modified="2008-04-29" version="1" precursor="true">MNSLSIKVQIGLAGALFVVVSVLFSLAYMVEANRLEANFNEYKSNTLASLEVTLAQPVFYYDFEQIDAVLSVMLASEKIYEITIKDHRGKMLGDSKQSTPVDPKAVTSDKLAFTTNDKPTGELTVSFSSAPITEALNQLKLSYFFQALVILLLSQLFIFIILKRLVITPLVHVSAVMEEIASGDGDLSHKLPVESNDEIGQLATAFNGFVAKIHGTISKVNETSELILQDASSLGDLSKSNNHRVQSQLKETEAAVAAVTQLNSSANEVAKNASSTAEATGLADKEVDNSQQQFDLGLEVSNRLADELSRSVVAVQELQQETQRIDEVVVVINAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATGEIQKMIQQVQTGVDETVSVMQASQTLSAEAVSHSEEIKLILSNVTSLVSNISNMNLEVAEAAGEQTYVTDDISKNLNDLATVSGSASLDSEQLAESSERLFHQGERLRALVGSFRLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIZ6</accession>
    <name>B1KIZ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC-type phosphate/phosphonate transport system periplasmic component-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323990.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1352"/>
    <dbReference type="EnsemblBacteria" id="ACA85644">
        <property type="protein sequence ID" value="ACA85644"/>
        <property type="gene ID" value="Swoo_1352"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1352"/>
    <dbReference type="eggNOG" id="COG3221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051472_4_1_6"/>
    <dbReference type="OMA" id="ANARMYS"/>
    <dbReference type="OrthoDB" id="988224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="267" mass="30041" checksum="FF1B808D84C454F5" modified="2008-04-29" version="1">MNKLTLTSCMAGNADPFVKKLTEYLATKLQLPMTSTLDISWQEREQKFDNGEIQICWICGLPYAWKADSTGSEIELLATPVLEASRYQNKAVYYSDIMVPAESDIQTFDDLQGASWAYNEPNSHSGSYLMRSHLAALGLDSRYLGKVIESGAHQESIKMLLNRDIDASAIDSWVFELELANDPSLATRLRVIETLGPSGFPPFIISKQVPEHLRQTLRSAMLAMDKDPLGREILDSVKISHFTQNGDRDYDSIREMAKLAQQVEWSK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ47</accession>
    <name>NADE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NH(3)-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="1">6.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nadE</name>
        <name type="ordered locus">Swoo_2791</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325403.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJ47"/>
    <dbReference type="SMR" id="B1KJ47"/>
    <dbReference type="STRING" id="392500.Swoo_2791"/>
    <dbReference type="EnsemblBacteria" id="ACA87067">
        <property type="protein sequence ID" value="ACA87067"/>
        <property type="gene ID" value="Swoo_2791"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2791"/>
    <dbReference type="eggNOG" id="COG0171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059327_3_0_6"/>
    <dbReference type="OMA" id="MAFLYDY"/>
    <dbReference type="OrthoDB" id="1152435at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00193">
        <property type="entry name" value="NadE_ammonia_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022926">
        <property type="entry name" value="NH(3)-dep_NAD(+)_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000099046" description="NH(3)-dependent NAD(+) synthetase">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="266"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00193"/>
        </source>
    </evidence>
    <sequence length="276" mass="30302" checksum="4F7149CF202801C7" modified="2008-04-29" version="1">MKGQILREMKVQPAIEASYEVERRIAFIKLKLKESHTQTLVLGISGGVDSSLAGKLCQLAVEQLNEETSSELYQFIAVRLPYHVQKDEDEAQLACQFISPSKLVTVNIHDGVSGVHQETLSGLTSAGIEVCDSTKLDFVKGNVKARMRMIAQYEIAGLTGGLVVGTDHSAENITGFYTKWGDGACDLAPLFGLNKRQVRQLAAYLGAPAVLVEKAPTADLEEDKPQLEDEVALGLTYEQIDDFLEGKAVDSYVEDRLIGIYKATQHKREAIPTIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ48</accession>
    <name>B1KJ48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Porin Gram-negative type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_2793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325404.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2793"/>
    <dbReference type="EnsemblBacteria" id="ACA87068">
        <property type="protein sequence ID" value="ACA87068"/>
        <property type="gene ID" value="Swoo_2793"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2793"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038238_3_1_6"/>
    <dbReference type="OMA" id="RNDTANH"/>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001702">
        <property type="entry name" value="Porin_Gram-ve"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00182">
        <property type="entry name" value="ECOLNEIPORIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767395" evidence="4">
        <location>
            <begin position="23"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="11"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="350" mass="37323" checksum="545E11FD694ECAEB" modified="2008-04-29" version="1" precursor="true">MMNRQITLLAACITCLCSPAQAIELNIYGQGHLSVDSVDDGQDSSIYVASNSSRLGFNGDHQINSDLKIIFQYETGVDLTAQGGNDGNGGAESSGQIFTKGRPSFLGIEGKFGTALAGHMPFLDQYANDYNLFADQVGDLGNLWEASGIPGRSDNVVYYKTPDFSGFDAAVTYVPEEGVDDSDYYLLKGNYVRDDLKLGVMYTSIGQGEMVDKDHTAAAVTLGYHFGRFSVGGGYQSEMDIGGSPGNDRDSFSLGGSMEVGDKGKIKAQFAVSSGEGDASDATQIAVGYDYQFDTQTTLYIAYANMDNDDNVNFSVNGKGHGDKVVPLMGNDPHAISLGIVYSFSHAVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJF5</accession>
    <name>B1KJF5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor plug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4375</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326953.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4375"/>
    <dbReference type="EnsemblBacteria" id="ACA88627">
        <property type="protein sequence ID" value="ACA88627"/>
        <property type="gene ID" value="Swoo_4375"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4375"/>
    <dbReference type="eggNOG" id="COG1629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006935_2_0_6"/>
    <dbReference type="OMA" id="SHQERDF"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764568" evidence="5">
        <location>
            <begin position="30"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="61"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="429"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="998" mass="108290" checksum="9C34510C05909B3D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL6</accession>
    <name>B1KJL6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324035.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1397"/>
    <dbReference type="EnsemblBacteria" id="ACA85689">
        <property type="protein sequence ID" value="ACA85689"/>
        <property type="gene ID" value="Swoo_1397"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1397"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123872_0_0_6"/>
    <dbReference type="OMA" id="QGKMCDW"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="18025" checksum="3D635CCCE1E9761E" modified="2008-04-29" version="1">MQVYLFDWGDTLMVDFPHTQGKMCDWEQVETIEGAQETLSYLSKQSQIYIATGADDSSETDIRQAFERVDLAQYISGYFCKANLGISKDSTEFYTRIIRKLGLTPCQAIMVGDTISKDVIPAQQAGLNAIWFNPNRLKNEKSLKQIHSLKELYIQEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL9</accession>
    <name>B1KJL9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324038.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85692">
        <property type="protein sequence ID" value="ACA85692"/>
        <property type="gene ID" value="Swoo_1400"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1400"/>
    <dbReference type="eggNOG" id="ENOG5033755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116660_1_0_6"/>
    <dbReference type="OMA" id="MATYMRY"/>
    <dbReference type="OrthoDB" id="1660610at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766715" evidence="1">
        <location>
            <begin position="20"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="179" mass="20425" checksum="9E8385D45D44E0D5" modified="2008-04-29" version="1" precursor="true">MKKVLLGLFLLAATGCSSNGLTELKQMDSNFDKEIVMTNDSKQTEQVRNIVTGWMLDNGYKVSKETASPTAQLDDDQVMFEFNANWWWDMATYMRYVNLDVTDSKGTKVAHLDFDSVRYGGFDKFGDAEERLNIIMEVFFQKISVQDAERQLEHGKDKKPKAAITCAYDCDKTTNKTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJU6</accession>
    <name>B1KJU6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325469.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2858"/>
    <dbReference type="EnsemblBacteria" id="ACA87133">
        <property type="protein sequence ID" value="ACA87133"/>
        <property type="gene ID" value="Swoo_2858"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2858"/>
    <dbReference type="eggNOG" id="COG3226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_21_1_6"/>
    <dbReference type="OMA" id="RMEYQGL"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="25772" checksum="5EC4BC304014314C" modified="2008-04-29" version="1">MSHPLSYIGRQTSRSDGEARRVTILEATLRLIVKEGIRGVRHRAVAKEAGVPLASTTYYFKDIKVLISDSLTYFAEKTLWMNKALEARSFELINFLGEDGKSRDDEHLVKYLTQFICEHIREQVKHSDDRILEMAFHEEALRNRQLAGAIKTLDDSFLATITLFFQKLESDTCLADAYQVLGLIKLLEYQYVMRGNIDEDKAQFESIVNASVRKIIGHRELSISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK44</accession>
    <name>B1KK44_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))</fullName>
            <ecNumber evidence="9">1.1.1.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4423</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.40" evidence="9"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327001.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4423"/>
    <dbReference type="EnsemblBacteria" id="ACA88675">
        <property type="protein sequence ID" value="ACA88675"/>
        <property type="gene ID" value="Swoo_4423"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4423"/>
    <dbReference type="eggNOG" id="COG0281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034446_2_1_6"/>
    <dbReference type="OMA" id="HKYAAVV"/>
    <dbReference type="OrthoDB" id="654531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004473">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="8">
        <location>
            <begin position="17"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="7">
        <location>
            <begin position="162"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="415" mass="44821" checksum="1ABE1AA4B6A0ECFF" modified="2008-04-29" version="1">MSDFRQQALDYHEFPVPGKTAVCLTKSAETSMDLALAYSPGVAEPVREIAANPDNAYRYTAKGNTVAVISNGTAILGLGNLGPLASKPVMEGKALLFKRFANIDSTDIEVKHRTPEEFINTVEAIADTFGGINLEDIKAPECFEIEKALIERCNVPVFHDDQHGTAIVTAAGMINALEIQGKKIEESIFVCMGAGAAAIACMTMLVKCGVQRENVYMLDRKGVIHTRRDDINEYKALFANNTDKRTLQDVIKGADAFLGLSGPDVLSAEDIALMAENPVVFACSNPDPEIKPEVAHEARKDLIMGTGRSDYPNQVNNVLCFPFIFRGALDVRASQINDEMKIAAVHAIAELAKEEVPASVLAAYPDVSELKFGPQYVIPKPMDPRLLQNVAKAVAQAAIDSGVAAIQSLPENYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK80</accession>
    <name>B1KK80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327037.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4459"/>
    <dbReference type="EnsemblBacteria" id="ACA88711">
        <property type="protein sequence ID" value="ACA88711"/>
        <property type="gene ID" value="Swoo_4459"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4459"/>
    <dbReference type="eggNOG" id="ENOG502Z7IA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_856962_0_0_6"/>
    <dbReference type="OMA" id="RTGNQHP"/>
    <dbReference type="OrthoDB" id="827796at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015004">
        <property type="entry name" value="MesX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08908">
        <property type="entry name" value="DUF1852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034367">
        <property type="entry name" value="DUF1852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="325" mass="37366" checksum="41FBA8D534D78CDF" modified="2008-04-29" version="1">MNNDFTFTIKSICLDENYHPSDSTRITTNFANLARGESRQANLRNALKMIDNSFNALAHWDNPAADRYSVELEIVSVDMDVEGDGEAFPSIEILKTNIIDNKTNERIEGIVGNNFSSYVRDYDFSILLLDHNKDQQQFSIPADFGDLHGKLFKYFVNSNAYKKHFKKLPVICLSVSDNKTYYRTENQHPVLGVEYQPNESSLTEQYFKKMGLQVRYFMPPNSVAPLAFYFFGDLLNDYSNLELISTISTMETFQKVYRPEIYNANAVAGKCYQPNLNNQDHSITQIVYDRAERGQLAIEQGKFAEEHFIKPYQSVLEHWSANCAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKF2</accession>
    <name>B1KKF2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A dehydrogenase</fullName>
            <ecNumber evidence="6">1.3.8.7</ecNumber>
            <ecNumber evidence="7">1.3.8.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Swoo_1504</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:17721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83721"/>
            <dbReference type="ChEBI" id="CHEBI:83727"/>
            <dbReference type="EC" id="1.3.8.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:14477"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83723"/>
            <dbReference type="ChEBI" id="CHEBI:83726"/>
            <dbReference type="EC" id="1.3.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="6"/>
    <dbReference type="EC" id="1.3.8.8" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324138.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1504"/>
    <dbReference type="EnsemblBacteria" id="ACA85792">
        <property type="protein sequence ID" value="ACA85792"/>
        <property type="gene ID" value="Swoo_1504"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1504"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012192_0_0_6"/>
    <dbReference type="OMA" id="DAGDVWL"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004466">
        <property type="term" value="F:long-chain-acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015396">
        <property type="entry name" value="DUF1974"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09317">
        <property type="entry name" value="DUF1974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="13">
        <location>
            <begin position="79"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="12">
        <location>
            <begin position="167"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="11">
        <location>
            <begin position="290"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1974" evidence="14">
        <location>
            <begin position="444"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACA85792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="745" mass="81362" checksum="CE632C61D9665E42" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG6</accession>
    <name>B1KKG6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324152.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1518"/>
    <dbReference type="EnsemblBacteria" id="ACA85806">
        <property type="protein sequence ID" value="ACA85806"/>
        <property type="gene ID" value="Swoo_1518"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1518"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111159_1_0_6"/>
    <dbReference type="OMA" id="IMRQSHV"/>
    <dbReference type="OrthoDB" id="1185302at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="109"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="186" mass="21261" checksum="67418DC2927081BC" modified="2008-04-29" version="1">MRNLELFNTASVDHLLWSTDNDITQLNSPALSIFTDFDHSQPMVIDSQTSAVKTSEIMEKTHAFMRLVVDGKNRFLGVITKHQLLHRKMVKMANKFNSNLDELLVTDMMVPREELQSLDYEQLTSAKVSDVVRSLQENGLHHILVIDHQQHHIRGLISANDVARKLKVPINIEQPPSFMHIFKAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI2</accession>
    <name>B1KKI2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, CopG family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324168.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1534"/>
    <dbReference type="EnsemblBacteria" id="ACA85822">
        <property type="protein sequence ID" value="ACA85822"/>
        <property type="gene ID" value="Swoo_1534"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1534"/>
    <dbReference type="eggNOG" id="ENOG5030PAM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149203_1_0_6"/>
    <dbReference type="OMA" id="YAMGETR"/>
    <dbReference type="OrthoDB" id="1905992at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="15872" checksum="DB8C8B817D8D8F91" modified="2008-04-29" version="1">MGLADLKKSSTQSNRGQTHVSRHQQVNIEDFIDEATHYAAGFKNTDQGMAEVITLASMVNQQPQQPSCKVKAQSAKAVTQIRKGNEPYRKATFTLSESAISHLAELASGCDVAKSKLIRFLIEHHFSLSDDERKTKERSIIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKI8</accession>
    <name>B1KKI8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_1540</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324174.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1540"/>
    <dbReference type="EnsemblBacteria" id="ACA85828">
        <property type="protein sequence ID" value="ACA85828"/>
        <property type="gene ID" value="Swoo_1540"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1540"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_1_6"/>
    <dbReference type="OMA" id="IGATYWK"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="10">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="197"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="261"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA85828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="362" mass="40000" checksum="2A63B159A5F15382" modified="2008-04-29" version="1" precursor="true">MITLIVIVCVAIGVSFLCSVFEAVLLSVTPSYIANLVHTNPSAADRLSKQKDNVESPLVSILTLNTIAHTVGAAVAGAQAAKVFGDEMLGVFSGILTFLILFFSEIIPKTIGANYWRTLAPSVSIALLWMERIMYPLIWMSQQVTQLLGKGDEGQYIRQEMSAMAKIGQESGELDEQESKILTQMLSVKEMPVSAIMTPRTVMFSLPSSMTQEEFAKKHKTSPFSRIPIFNDDPDDVIGYINRNDILLSERKTPQASIGELKRNLVVIPETAKILPLFQLLIKRNTKIAMVVNEYGTGEGIVSLEDIIESLLGLEIVDSNDPVTDMQQLARKQWEKRMTDKGITFSDDGEFDSYVETPKSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKM1</accession>
    <name>B1KKM1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325574.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2967"/>
    <dbReference type="EnsemblBacteria" id="ACA87238">
        <property type="protein sequence ID" value="ACA87238"/>
        <property type="gene ID" value="Swoo_2967"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2967"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_6"/>
    <dbReference type="OMA" id="TSWQALK"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="14"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="313" mass="33724" checksum="AAA5A221A521517C" modified="2008-04-29" version="1">MSPLMKAVQINEFGDHSVLLLNDVVIPTPNENEVLIKVKSAAVNPVDWKIREGYLQPLLNHSLPLTLGWDVSGEVVAIGKNVTNLKVGDAVYSRPDIAKNGSYAEYQTVVAEEAALKPSSFTWQEAAGVPLAALTAWQSLYGLAKLESGDRVLIHAGSGAVGQFAIQLAKLRGAYVYTTTSSKNTELVMGLGADQSIDYHQDDFSQLKDIDVVFDTIGGETQAKSWKTLKKGGRLVSITETPDDAIAAKYDISAFFCFVQPNGEQLKKLAELADAGQLTVTIDSEFSLSQVAEAHKRSETGRAQGKIIINVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKT7</accession>
    <name>B1KKT7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choloylglycine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4492</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327069.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4492"/>
    <dbReference type="EnsemblBacteria" id="ACA88743">
        <property type="protein sequence ID" value="ACA88743"/>
        <property type="gene ID" value="Swoo_4492"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4492"/>
    <dbReference type="eggNOG" id="COG3049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045206_0_1_6"/>
    <dbReference type="OMA" id="VMTNPPS"/>
    <dbReference type="OrthoDB" id="636485at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBAH" evidence="3">
        <location>
            <begin position="2"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="39690" checksum="547A6AA006AF1878" modified="2008-04-29" version="1">MCTRILNSLNPNFPITARNMDWSRPINVYLYQFPKGETKFGLSKQERDELTNEQASLEWTSAYSSVASVMGDDHIGLGSADGMNSEGLVVNALFDSDSSFADEALHHQDSTPRLSVLRWAQFTLDSFANVNCALEYYRNSHILLISGVVPDGAETAREAKLHLSLSDSAGNSAILEIREGKLIIHSDSTYRVVTNQPDYDTQLKLDYYWQYMWGKTEPKIKTPVNLAPGGVTSTQNFERASYYLAMTDSAASEDEALAQTRTMLGTCTTPVGFNSHHSEHGTSTRWSNLANSINKTYYFINQLTLTPVWLTIHKNIKDCKRVELVQVIDNKVKNWRLAGDLEGELVNCHDPLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKV7</accession>
    <name>B1KKV7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4512</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327089.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88763">
        <property type="protein sequence ID" value="ACA88763"/>
        <property type="gene ID" value="Swoo_4512"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4512"/>
    <dbReference type="eggNOG" id="COG3264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037945_1_1_6"/>
    <dbReference type="OMA" id="ITIPNKH"/>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="277" mass="30536" checksum="1F968CBE2742F825" modified="2008-04-29" version="1">MNEDQLEQELQQLQGVYTFLYEFLVQYSFQIIGAILIFLLGLWVANKISNLVASQLKKHNIDITLSNFVTNLLRILIIVMVGIVALGKLGISITPMVAAIGAASLGAGLALQGMLSNYAAGITIIVTRPFVVGNTISIREVTGVVQDIFLGMTVLINEEGEQINIPNKHIVGEILHNSFANKLVETNFNISYKSDPDSVIALATEVISQSPRVFQEQSPLIGINGFNSIGIEISIRYWVPTDTYYQDKYQTNLAIYRALLAANIEIPCPVKEVHIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA1</accession>
    <name>B1KLA1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322791.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0141"/>
    <dbReference type="EnsemblBacteria" id="ACA84442">
        <property type="protein sequence ID" value="ACA84442"/>
        <property type="gene ID" value="Swoo_0141"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0141"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_35_0_6"/>
    <dbReference type="OMA" id="HIANSEW"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="34450" checksum="23D4584B50E64EAD" modified="2008-04-29" version="1">MNWSLYQLEAFVLSVKYGSFSAAARKLGRAQSRISTAIGHLEDDLGFELFDRSARLPVLTPCGEDMFIEAQAVLQQCQRLESRAMTLSTGQEISLTVAMDEAVPINAFESLFEQVSIKFPLLKLTIINGSQDDIGLWVDEGKADMGILFHSRNELPESLEFMSIGQFKQSLIVSVNHPLAQFSAPKIKELNQHRQLVIRDRMGDKQAKALAANHWYIDSYYYMTALVIRGVGWALVPEHIANSEWYSDDIVTLSTEHIPSPLLVEIGVVNRRDQAYGPVMEWIFLEIESMFKNKVNNYSNKSESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC0</accession>
    <name>B1KLC0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="7">IMP dehydrogenase</shortName>
            <shortName evidence="7">IMPD</shortName>
            <shortName evidence="7">IMPDH</shortName>
            <ecNumber evidence="7 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">guaB</name>
        <name evidence="16" type="ordered locus">Swoo_1559</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="7 14"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324191.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1559"/>
    <dbReference type="EnsemblBacteria" id="ACA85845">
        <property type="protein sequence ID" value="ACA85845"/>
        <property type="gene ID" value="Swoo_1559"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1559"/>
    <dbReference type="eggNOG" id="COG0516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022552_2_1_6"/>
    <dbReference type="OMA" id="MGYCGAK"/>
    <dbReference type="OrthoDB" id="532857at2"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 7 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="93"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="153"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="338"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="361"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="385"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="7 8">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="248"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="298"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACA85845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="490" mass="52121" checksum="4EC18A242DC78394" modified="2008-04-29" version="1">MLRLKKEALTFDDVLLVPAHSTVLPNTAVLKTRLTNTIELNTPIVSAAMDTVTEARLAIAIAQEGGLGFIHKNMTIEQQAEEVRKVKIYEAGIVQQPVTVKPTTTLDELKVLTEKNGFAGYPVVNDANELVGIITGRDVRFITDWSRTVDKVMTPKDRLVTVPEGTKLDEVQTLMHSHRVEKVLVVDANFKLKGLITVKDFQKAERKPNACKDELGRLRVGAAVGAGPGNEERVDALVAAGVDILLIDSSHGHSEGVLQRIRDTRTKYPELQIVGGNVATAEGALALVDAGVNAVKVGIGPGSICTTRIVTGVGVPQITAVSDAAEAVKHLNIPVIADGGIRFSGDLAKALAAGASCIMAGSMFAGTDEAPGETELYNGRAYKSYRGMGSLGAMTQTQGSSDRYFQSDNAADKLVPEGIEGRVAYKGKLKEIIHQHMGGLRSCMGLTGCGTIKELNEKAEFVKITSAGMGESHVHDVTISKEAPNYSSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC7</accession>
    <name>B1KLC7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase, subunit II</fullName>
            <ecNumber evidence="8">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1566</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324198.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1566"/>
    <dbReference type="EnsemblBacteria" id="ACA85852">
        <property type="protein sequence ID" value="ACA85852"/>
        <property type="gene ID" value="Swoo_1566"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1566"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_0_0_6"/>
    <dbReference type="OMA" id="FLWGVAF"/>
    <dbReference type="OrthoDB" id="761975at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="379" mass="42055" checksum="D98548ED70D8FFF2" modified="2008-04-29" version="1">MFDYEMLRLIWWALIGVLFIGFAVTDGFDMGVGALLPIIGKDDTERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYGVSFSGFYVAMMLVLFALFLRPVGFDYRSKIEDPRWRKSWDWALFVGGFVPPLIIGVAFGNLLQGVPFNFDEYLRATYHGGFFGLLNPFGLLAGIVCVSMFMMQGATWLQMKTEGELRVRAANASQILSIVLFICFAAAGVWLVNGIDGYVVTSTIDTYGISDPTLKTVAVEAGAWLTNYDKYPITMLFPILGLVMPILVLFSSRLNRSGFAFLFSSLAIAAVILTCGAAMFPFVMPSSLEPNVSLTMWDSTASEVSLTVMTWAAIIFVPIVLSYTVYTYLKMFGRLSRSFIDNNKTSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLG9</accession>
    <name>B1KLG9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_1608</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324240.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1608"/>
    <dbReference type="EnsemblBacteria" id="ACA85894">
        <property type="protein sequence ID" value="ACA85894"/>
        <property type="gene ID" value="Swoo_1608"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1608"/>
    <dbReference type="eggNOG" id="COG1344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011142_2_2_6"/>
    <dbReference type="OMA" id="ENEKRMN"/>
    <dbReference type="OrthoDB" id="636786at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042187">
        <property type="entry name" value="Flagellin_C_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00207">
        <property type="entry name" value="FLAGELLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="6">
        <location>
            <begin position="188"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="273" mass="28686" checksum="03AEEECA819C1E85" modified="2008-04-29" version="1">MAITVNTNVTSLKAQKNLNTSSGNLATSMERLSSGLKINSAKDDAAGLAISNRLNSQVRGLEVGMRNANDAISIAQIAEGAMQEQTNMLQRMRDLTIQSENGANSTEDLAALKAEMDQLATEIDNIGTSTAFGNTKLLQGGFSAGKIFQVGHQEGEDVKVVVKKTDKTSLSVAALNNATSANRASSLAAIDKAIKTIDTQRADLGAVQNRLAHNISNSANTQANVADAKSRIVDVDFAKETATMTKNQVLQQTGSAMLAQANQLPQVALSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLM4</accession>
    <name>B1KLM4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325657.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3050"/>
    <dbReference type="EnsemblBacteria" id="ACA87321">
        <property type="protein sequence ID" value="ACA87321"/>
        <property type="gene ID" value="Swoo_3050"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3050"/>
    <dbReference type="eggNOG" id="ENOG5033DKM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1204119_0_0_6"/>
    <dbReference type="OMA" id="FGQLTDY"/>
    <dbReference type="OrthoDB" id="1557307at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="27718" checksum="8CDB1D4DA4E6F170" modified="2008-04-29" version="1">MHVEVHIFLYAENLTMNPIANAPSTAGQLTNTSLADKYGINSHQAEAGQHSDKVTLSQSNQPPKAASKEQVKDESVSLSPRAMRAQKIESMAKDFFADGQFSISDLPKLVQRLHQDGILSDTQLNRLSEGGIELPRPQGSVEDMKTFIESKRGELEKNASDENTMSNVLIKLLDDAEGVLNKMDNIQSKELSQQASRVSSQLNVYLKSDVQMSGEERQQWQGLRSVMQLASSMGDSQQASGQLSSYLALGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLW9</accession>
    <name>B1KLW9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327174.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4599"/>
    <dbReference type="EnsemblBacteria" id="ACA88849">
        <property type="protein sequence ID" value="ACA88849"/>
        <property type="gene ID" value="Swoo_4599"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4599"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026234_0_1_6"/>
    <dbReference type="OMA" id="WPLCAGR"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="132"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="50572" checksum="1511C653797FD448" modified="2008-04-29" version="1">MTELLKSWLSKGPSSQQLISFNHHDIVTGAVFTGQVAHLHQQLVQSPSKRWLLASESSDLFAVGLCAAMLAGKEIILPANTQTGSLSEITHEFDGVISDQAICEGKCFIMLKKDHALASATWPVSTQFGELILFTSGSSGHPKAIHKTLNQLDAEVTVLEHTFAKHLPQCSVISTVSHQHIYGLLFKILWPLAANRPFLSDLVEYPETLTYYTSLFPNLCLISSPAQLSRLPDALDNEAQLRAPSLVFSSGGPLNYDSAQGIAQCYGKQPIEVFGSTETGGIAFRRQTQENQAWQVFHGIEIKQDKKDSALNLKSPYLEDANWLRCEDQIELVDEGLFHLCGRLDRIIKIEEKRVSLVQMEALLESHPLIEHGALVMLTEPRTQLGAAITLSKLGKKALESEGKLSLNNHFKAHLLTQFERVTLPRRWRYPDTLPLNKQGKRVQAQILELFDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLZ2</accession>
    <name>B1KLZ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327197.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4622"/>
    <dbReference type="EnsemblBacteria" id="ACA88872">
        <property type="protein sequence ID" value="ACA88872"/>
        <property type="gene ID" value="Swoo_4622"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4622"/>
    <dbReference type="eggNOG" id="COG5492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1204125_0_0_6"/>
    <dbReference type="OMA" id="PMINAYL"/>
    <dbReference type="OrthoDB" id="1085290at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011460">
        <property type="entry name" value="DUF1566"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07603">
        <property type="entry name" value="DUF1566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="26200" checksum="F164D96DC1D6DDBC" modified="2008-04-29" version="1" precursor="true">MKFKRGAYRRFTLSLLLLTLLLSGLMLLQTEPANSSIDERLIKLSAQGETLAPWQGPWACIHDTLTGLLWENKTNNESIHDGYWSYSWFNEGKGQTNSGDCYFEAQRCDTQDLIRRTNEEKLCGITGWRLPTKAELSSLLEQQDRPQAPQLRTDFFQQIKAGDYWSAQGSMPLEGHYQHLGQGASAINFYQGRFHNLPYRNAAFAILVTDKWPKSQYTAGVTSRTVSKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM56</accession>
    <name>B1KM56_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322818.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0168"/>
    <dbReference type="EnsemblBacteria" id="ACA84469">
        <property type="protein sequence ID" value="ACA84469"/>
        <property type="gene ID" value="Swoo_0168"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0168"/>
    <dbReference type="eggNOG" id="ENOG5030PG7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2332102_0_0_6"/>
    <dbReference type="OMA" id="CENSSIP"/>
    <dbReference type="OrthoDB" id="1950421at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="6"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="98" mass="10940" checksum="90B36D20691E38BE" modified="2008-04-29" version="1">MSDQTIKLDSEITIRNIQPVFTQLCELFTQAEILHIDASQLSRVDTAGAQLLHLFSKTCDARSLKVDWLGCQDDLLESLGELGISLPHLKVDTLEEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM74</accession>
    <name>B1KM74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322836.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0186"/>
    <dbReference type="EnsemblBacteria" id="ACA84487">
        <property type="protein sequence ID" value="ACA84487"/>
        <property type="gene ID" value="Swoo_0186"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0186"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054734_0_0_6"/>
    <dbReference type="OMA" id="MSAFYHR"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="250"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="318"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="398" mass="45518" checksum="4308455F69F170FD" modified="2008-04-29" version="1" precursor="true">MSAFYHRCRFLFLPLFVTALSLAIFQFSQPRLNAWHETIAQLPFWLLSISILIAIQFNRSRLAYLAALLQAYYLFTSSAQFTIEGLDNYSEQLLLGGVFTITWFAFIKDRGLLSPHSLIRTLGIILSFSAAFGWQWANVTFDNDLKLYLPEFITIEIRTLILLSLCTLLVFLRGLWLSNLVSTAIVITLLLWGVNFLLPNYLPSAVSLSMLAIIYLLTVLADSYFLAYRDELTGLASRRALYNLVLSLGRKYTVAMLDIDHFKKFNDTYGHDVGDQVLKLVASKIAEVTGGGKAFRYGGEEFTIVFSRKDLSSVLPHLEKVRKEIEKYDIVLRDEKRKKQTKAKRNKAQERNSKRVVNVTISIGVADHQHRESFEQTMKEADKALYRAKKKGRNQLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM82</accession>
    <name>B1KM82_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322844.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84495">
        <property type="protein sequence ID" value="ACA84495"/>
        <property type="gene ID" value="Swoo_0194"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0194"/>
    <dbReference type="eggNOG" id="ENOG5030YZV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1814504_0_0_6"/>
    <dbReference type="OMA" id="PKYLHAS"/>
    <dbReference type="OrthoDB" id="1962203at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="161" mass="16973" checksum="58EBEF21D450522E" modified="2008-04-29" version="1" precursor="true">MSKQLAHLVLIISLVGQFLLTPAMAMPSLLHAYSHAQMNDVEHDAAGVSTMIETAVKSQLLPPQSPLLTGQSDTLDSRQNCDAIAGILVNDNSDVSIDCDALCEMMGVGECVSHCANATGILIQANFALQVPESSASIQAGFWSTQTADPAPFNPPPIRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB6</accession>
    <name>B1KMB6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322878.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0228"/>
    <dbReference type="EnsemblBacteria" id="ACA84529">
        <property type="protein sequence ID" value="ACA84529"/>
        <property type="gene ID" value="Swoo_0228"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0228"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1122746_0_0_6"/>
    <dbReference type="OMA" id="HLAFRLY"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="174"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="238" mass="27963" checksum="9218ED790ABCB0E0" modified="2008-04-29" version="1">MYLSQKELCTMMDLVSFTLQHNTTLGSRQLLLDKLMEMFRADYGASCCWNPNEKYYQEGVFSNMSLDNISKYNDYYQFHDPITNKLRQFRRAVAVSEVISRDQLIQTEFYNDFLQRDGLSFGVNLHIYCGQEHVFDVRLWRSQQQGDFDVKHLNQLDLLLPYLRAMGEREPLKESLSFNLFTQRELEVISQIKSGMNDKNMARTMNVSVTTLRSHIRSIYKKADVHSRTELISKLAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG7</accession>
    <name>B1KMG7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide biosynthesis protein CapD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324311.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1680"/>
    <dbReference type="EnsemblBacteria" id="ACA85965">
        <property type="protein sequence ID" value="ACA85965"/>
        <property type="gene ID" value="Swoo_1680"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1680"/>
    <dbReference type="eggNOG" id="COG1086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013560_5_0_6"/>
    <dbReference type="OMA" id="IIIAMPS"/>
    <dbReference type="OrthoDB" id="662797at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_2" evidence="3">
        <location>
            <begin position="283"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="642" mass="70328" checksum="F6360618C34CB588" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI0</accession>
    <name>B1KMI0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324324.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1693"/>
    <dbReference type="EnsemblBacteria" id="ACA85978">
        <property type="protein sequence ID" value="ACA85978"/>
        <property type="gene ID" value="Swoo_1693"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1693"/>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_574768_0_0_6"/>
    <dbReference type="OMA" id="TWIDESV"/>
    <dbReference type="OrthoDB" id="399610at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="NTP_transferase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="481" mass="53409" checksum="272AAFBFEF68D51F" modified="2008-04-29" version="1">MQAIIFANRIGDELAPLDQHYCPALLPVGNKPVIEYTLEDIATSGISEVKLIISSQAQEVEQQLGDGERWGIRIEYFLSKPQEKTKSVLNRLSLPSNESILIIRGDIFRSPCIASFINFSRQFPNEFVQAKMANENAGMSMLPAAQPYLDGIDWPLINHGENNSVVTLVLHGLCNMLDSFQAYLQVNLSLARNDIPALTPMERSFTSANPEQDFYVGAKADTQGLDKQHAWGIIGENSKVDPSVEMKNTVIIGNDTLIDKGSVLESCLILPHTYVGEGLEVNNSILCKNLLINLNTDGHILVDDQALIGPSQLEANIIPSQTHFMTRLFILAILLISLPFWPLLATYSLIRVLLLKLKAKPIIQEMINDNLGQSLVVYSFNTPTRIISLLPQLCLVLTGQLDLFGAPAQIRYASGQNKHRLGVFGPVQLLLDEDAPEEERSLLMLEFDNNSSNTKYLSLLKQSLFMPKALHSQESVNKAIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMI5</accession>
    <name>B1KMI5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324329.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1698"/>
    <dbReference type="EnsemblBacteria" id="ACA85983">
        <property type="protein sequence ID" value="ACA85983"/>
        <property type="gene ID" value="Swoo_1698"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1698"/>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044332_0_0_6"/>
    <dbReference type="OMA" id="DGRAQLM"/>
    <dbReference type="OrthoDB" id="744535at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="337"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="468" mass="51763" checksum="5A0DC46D8518B5E3" modified="2008-04-29" version="1">MKKHHPSQLLWLRRAAVKGSSLPVNARRWVYIKTAIGALAIIWTLVTLVLVISPTRFESKWTLILPGAGAGALVNLDSIGQATSTNSSPYASSAIDPRENYKALSMSSVLINAAAKTIKIPNYKMGKPKLKLPNQTGLMQFTISGPSAEGAQEKAWAHYHSLQALLSRLRDDETQQRENGVKVGLDGFASKVSQSQDKILSFQSQIGLVSLDQFKELALTIERLRHNRVNMVSKLQGVIASQKMLEMHLSLNAKQAADLLKLKNDQLYQQLLVIYTQATTTLAEYSGRYGKKHPQVMTQKHQQNALFQALKKRCKILLGYQDDVLMLKLSADDIDGRAQLMRQLISLNTEAEGLNQEIKSLTTQIAAWDTRLEDSNDDAAKLEDLHREHQLATAVFTSAIAKLDIGKADIYSAYPLIQLLAPPSLPEKPNKLSTVLALLGGIISSIFCLAGLSILWVRKPILQKILMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN04</accession>
    <name>B1KN04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4711"/>
    <dbReference type="EnsemblBacteria" id="ACA88961">
        <property type="protein sequence ID" value="ACA88961"/>
        <property type="gene ID" value="Swoo_4711"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4711"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081861_0_0_6"/>
    <dbReference type="OMA" id="REHWRFI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="204" mass="22899" checksum="17FC0CFB1CEA1FE7" modified="2008-04-29" version="1">MMGIRAQQKEKTRRALVDAAFNQLNAERSFSSLSLREVAREAKIAPTSFYRHFKDMNELGLTMVDEGGLTLRQMMRKGRQRAEAGGSVIRISVDTFMEVLESNPNVFRILLHERSGTSAPFRAAVAREIEHFISELAHYTEATAKRSPELARAQAEALVTLVFNAGAAALDMKRVDRKILADRLVIQLRMVAKGSEALQHKMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN28</accession>
    <name>B1KN28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General secretion pathway protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_4735</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327302.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4735"/>
    <dbReference type="EnsemblBacteria" id="ACA88985">
        <property type="protein sequence ID" value="ACA88985"/>
        <property type="gene ID" value="Swoo_4735"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4735"/>
    <dbReference type="eggNOG" id="COG3031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068012_0_0_6"/>
    <dbReference type="OMA" id="WRIIPEP"/>
    <dbReference type="OrthoDB" id="1597080at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024961">
        <property type="entry name" value="T2SS_GspC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001639">
        <property type="entry name" value="T2SS_protein-GspC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11356">
        <property type="entry name" value="T2SSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01713">
        <property type="entry name" value="typeII_sec_gspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSC" evidence="9">
        <location>
            <begin position="25"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA88985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="32915" checksum="1CA306E625F0AF3F" modified="2008-04-29" version="1">MDLLDKVISKAADIPHKPLSTSVFWVGLIIVLYLFAQITWKLVPTSEPTTNWRPTPASVSAGKSVSVAQLQALSLFGKADEASSQPKVAPVEEQITDAPKTSLSIQLTGVVASTAQQKGLAVIASSGSQNTYSLGDKIKGTSASLKEVYADRIIITNSGRYETLMLDGLKYETNGQANKQLQQAKSVRKVDQRQNRQVAQDILESRDELLADPSKLTDYLAISPVQREGQLQGYRLNAGKDRDLFKQAGFRANDLAKSINGYDLTEMTQALEVMAQLPELTEISLMVERDGQLVEIMFSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN39</accession>
    <name>B1KN39_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methionine sulfoxide reductase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327313.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4747"/>
    <dbReference type="EnsemblBacteria" id="ACA88996">
        <property type="protein sequence ID" value="ACA88996"/>
        <property type="gene ID" value="Swoo_4747"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4747"/>
    <dbReference type="eggNOG" id="COG0322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052782_2_0_6"/>
    <dbReference type="OMA" id="AEIMNWT"/>
    <dbReference type="OrthoDB" id="880308at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025579">
        <property type="entry name" value="DUF4357"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14267">
        <property type="entry name" value="DUF4357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="49"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="301" mass="33027" checksum="8137794FD6B3C7DF" modified="2008-04-29" version="1">MSIGRTIRIYLDDGSISGIRHAEIVNWTGQAISAPRTQVKSLSDWEESKKPGVYFLFGVDETSGNSAVYIGEAENVLDRLQSHVATKDFWNEVVLFTNKDENLTKSHVKYLESRLVQFAKSAERYVVLNGNEPQQPVLPRGDRDAMEEFLSNIRVLLGVIGHKALESLAQHEVPKSLENQAHEESALASNNSNFSLKVKGISAKAVLTDEGIVVLSGSMVADKIRDSLSTGYQKLRAELIDSGAVVKGSDGILRFTRDRLFTSPSQAAAIIAGYAINGRHHWQTESGKTLKAVEESEATSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE4</accession>
    <name>B1KNE4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LamB/YcsF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324367.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1736"/>
    <dbReference type="EnsemblBacteria" id="ACA86021">
        <property type="protein sequence ID" value="ACA86021"/>
        <property type="gene ID" value="Swoo_1736"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1736"/>
    <dbReference type="eggNOG" id="COG1540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069535_0_0_6"/>
    <dbReference type="OMA" id="PHGRLGN"/>
    <dbReference type="OrthoDB" id="918580at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="PTHR30292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="242" mass="26861" checksum="FDF038E55FDB4FFE" modified="2008-04-29" version="1">MKINCDLGESFGSWCKGQDELVMPLIDQANIACGFHAGDPQIMENTVKLAIENNVEIGAHPGYPDLIGFGRRPYSCDLLELRSILLYQIGALHAMCSSSGTKVSYVKPHGALYHSMMKNEDVMKCILQTLSSLPFELSLMVQASTEYCKHIDMASSLGVKLIFEAFADRSYVDHNNLAGRDIPNAVKHDSDEIFLNIKNMKENRQVVSISGEIIDMKMDTICLHGDNESSFLALDKFHRAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNS6</accession>
    <name>B1KNS6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325870.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3264"/>
    <dbReference type="EnsemblBacteria" id="ACA87534">
        <property type="protein sequence ID" value="ACA87534"/>
        <property type="gene ID" value="Swoo_3264"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3264"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_5_6"/>
    <dbReference type="OMA" id="ASGRNCY"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="165"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="293" mass="33164" checksum="9D6742EF6A3CA434" modified="2008-04-29" version="1">MDFGLAAEFSPEEYRYQPEIYQVNDPEPDLVKIIQHLHESLDPRTVFACFGKIMGQYLPIDGVQMTFKRHQFNWGRTQGIKVTQQLAFSGEAANLTYSLKSPLTPSQSQRLQTMQTLVLLPLFNAIQFQDISQKAMYDSLTKLGNRHYYAESLKKAIATSSRHDNPLSIVILDLDNFKKLNDSYGHLLGDEVLSEFGQLLTSAIRDTDQAFRVGGDEFVVIVRGDVKAASVLCERVLTSISSHSLFEKYQAMTSLGVSQWKQDETATDVYERADKALYRAKAAGRRCFKVDEI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU3</accession>
    <name>RS2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsB</name>
        <name type="ordered locus">Swoo_3281</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325887.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNU3"/>
    <dbReference type="SMR" id="B1KNU3"/>
    <dbReference type="STRING" id="392500.Swoo_3281"/>
    <dbReference type="EnsemblBacteria" id="ACA87551">
        <property type="protein sequence ID" value="ACA87551"/>
        <property type="gene ID" value="Swoo_3281"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3281"/>
    <dbReference type="eggNOG" id="COG0052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040318_1_2_6"/>
    <dbReference type="OMA" id="SYIDRAY"/>
    <dbReference type="OrthoDB" id="1623045at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000115058" description="30S ribosomal protein S2">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <sequence length="242" mass="26690" checksum="D07D45B3F6A858A8" modified="2008-04-29" version="1">MTTVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNGVHIINLEHTVPMFNEALAFISNVASKKGKVLFVGTKRAASEAIKESAISCDQYYVDHRWLGGMLTNWKTVRQSIKRLKDLESQSVDGTFDKLTKKEALMRTRELEKLEKSLGGIKNMGGLPDVIFVIGADHEHIAIKEANNLGIPVVAVVDTNSSPDGINYIVPGNDDAMRSIRLYTESVAAAAKAGRGQDLAVQAEQDGFVEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNW5</accession>
    <name>B1KNW5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325909.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3304"/>
    <dbReference type="EnsemblBacteria" id="ACA87573">
        <property type="protein sequence ID" value="ACA87573"/>
        <property type="gene ID" value="Swoo_3304"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3304"/>
    <dbReference type="eggNOG" id="COG2091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057011_4_1_6"/>
    <dbReference type="OMA" id="NTADSYC"/>
    <dbReference type="OrthoDB" id="1542506at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="137"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="290" mass="32612" checksum="91CA8C908AE726DB" modified="2008-04-29" version="1">MSPIPTLSPSPEVTLYFCPLATEAIGPDEAELIRSWLPEDELTKVSRYVQADARDKALVVRGYLRGILSLTRSGDVTLSPSEWQFEYGEKGKPDLITEQALLSGLKFNISHSGDWLVVAVYQGQLGLSGGERASIELGVDIERNRDSTNIYPILNHYFTQSETDELLSLPESSQRQRFFDLWALKESYIKAKGLGLALSLKSFYFDFARATKQKIEVSKLNNPAVECVLFDGIELYLVREEGDKCAADTWCLFLGRLSEEYRFAVSASHIGTFNLKAYQLTLTEMLSRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPC0</accession>
    <name>B1KPC0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323039.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0391"/>
    <dbReference type="EnsemblBacteria" id="ACA84690">
        <property type="protein sequence ID" value="ACA84690"/>
        <property type="gene ID" value="Swoo_0391"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0391"/>
    <dbReference type="eggNOG" id="ENOG502ZBR1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2107361_0_0_6"/>
    <dbReference type="OMA" id="PCTFSQR"/>
    <dbReference type="OrthoDB" id="1484829at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765104" evidence="1">
        <location>
            <begin position="25"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="115" mass="12917" checksum="6220580FED5DF460" modified="2008-04-29" version="1" precursor="true">MKLSHTYLSGLAVLLSIIATPSQADTMQSRCDIYDKPQGELLTSTPCTFSQRQGYISINRDDGISYNLAPVDEAYIGTFEDQNGNWVYRKSGLSPDGVIFKMPTEYLYLYWGKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPE0</accession>
    <name>B1KPE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323059.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0411"/>
    <dbReference type="EnsemblBacteria" id="ACA84710">
        <property type="protein sequence ID" value="ACA84710"/>
        <property type="gene ID" value="Swoo_0411"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0411"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_929919_0_0_6"/>
    <dbReference type="OMA" id="NIANTVW"/>
    <dbReference type="OrthoDB" id="2072309at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="306" mass="35289" checksum="226AF60838FAA7FB" modified="2008-04-29" version="1">MEFIKTISDTFQSLAQNFNDRIKSPIGGAFFFSWIIFNWKLVYYILMQTESPSKKIAYVETHFLDIWPLLISPALASIAYVIFYPVIYNGSNLIWTFIDKNLKTKVAVAIEKKVLLTTEDSQQLYNLIREQKTRHEEEVKKLRGQIEALSKITPSPQQIEPSFIETVDTHLKPTDNAVGRHNKQTELPINQHDYDAEIKAKLTTEKGKKGLTALIMEMIDTNANSSANSANLSMYHLIIRTIFKSEPNGLSTQEIVQRVKNIDYVDVETLISDLENYKMVVMDTNTREYTLTNRTINKIYSMLDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPK7</accession>
    <name>B1KPK7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitrite reductase (NAD(P)H), small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1876</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324506.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1876"/>
    <dbReference type="EnsemblBacteria" id="ACA86160">
        <property type="protein sequence ID" value="ACA86160"/>
        <property type="gene ID" value="Swoo_1876"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1876"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_3_0_6"/>
    <dbReference type="OMA" id="AAPLYKQ"/>
    <dbReference type="OrthoDB" id="1681886at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03529">
        <property type="entry name" value="Rieske_NirD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017881">
        <property type="entry name" value="NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012748">
        <property type="entry name" value="Rieske-like_NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40562">
        <property type="entry name" value="PTHR40562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13806">
        <property type="entry name" value="Rieske_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02378">
        <property type="entry name" value="nirD_assim_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="4"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA86160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="13242" checksum="1D8420AB6C66E189" modified="2008-04-29" version="1" precursor="true">MRWVDICDESALPRFGGIAAWCENRAVAIFNLGEQGLYAMSNTDPATGVSLLSRGLICELEGDIWVASPLHKQHYSLTSGECIEDESLRVQLYPISCEGGRVWLQTASEKSEPRVLRSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPU3</accession>
    <name>B1KPU3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325961.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3357"/>
    <dbReference type="EnsemblBacteria" id="ACA87626">
        <property type="protein sequence ID" value="ACA87626"/>
        <property type="gene ID" value="Swoo_3357"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3357"/>
    <dbReference type="eggNOG" id="ENOG5031IFR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2620096_0_0_6"/>
    <dbReference type="OMA" id="LRRQINF"/>
    <dbReference type="OrthoDB" id="1929429at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021753">
        <property type="entry name" value="DUF3319"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11782">
        <property type="entry name" value="DUF3319"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="78" mass="8958" checksum="FBA51BAB4A1105F2" modified="2008-04-29" version="1">MRKLIYQGFILTNNRGLTDSWSLSIGGQTRTGSLFELRRQINFYCELGVLPPNRNTIQTKVNATPLKQRTSSRRNTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ08</accession>
    <name>B1KQ08_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327438.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4872"/>
    <dbReference type="MEROPS" id="C40.004"/>
    <dbReference type="EnsemblBacteria" id="ACA89121">
        <property type="protein sequence ID" value="ACA89121"/>
        <property type="gene ID" value="Swoo_4872"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4872"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016043_9_3_6"/>
    <dbReference type="OMA" id="QFIHASK"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="55"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="183" mass="20514" checksum="B63424B6346D7CD6" modified="2008-04-29" version="1" precursor="true">MVVSLNFPFTIWINFLLKPLLSLLFILLITACSSAPPSPSTGSGGAKTNAQISQSALEKQLLTFYKGWKGVPYRLGGMSKRGVDCSGFVYLAYQQLLTKQVISAFPRTTADQVELGRKVSKSQLKTGDLVFFKTGWSTRHVGIYLSDNRFLHASTSQGVMISRLDNSYWKQKYWQSRRLSFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ81</accession>
    <name>B1KQ81_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_0438</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323085.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0438"/>
    <dbReference type="EnsemblBacteria" id="ACA84736">
        <property type="protein sequence ID" value="ACA84736"/>
        <property type="gene ID" value="Swoo_0438"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0438"/>
    <dbReference type="eggNOG" id="COG1045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_0_1_6"/>
    <dbReference type="OMA" id="HPKIRHG"/>
    <dbReference type="OrthoDB" id="1639008at2"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00971">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SATase_N" evidence="9">
        <location>
            <begin position="5"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA84736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="266" mass="28658" checksum="8B66F44F6943EC9D" modified="2008-04-29" version="1">MRYEVWEQLRVEAETLVQKEPLLASHVYSSVLNHECLGSALSFIVANKLSDGVVSPFTFRELFDKAFIHCEQMLTNVATDIKAVKERDPAVESYLTVLLNLKGFQAIQVHRLASCLWHQGRTELAQFIQSRNSEVFGVDIHPACKMGTGIMFDHATGIVIGETAVIENNVSLLQGVTLGGTGNQQGDRHPKIRAGVLIGAGAKVLGNIEVGEGAKVGAGSVVLADVDAHTTVVGVPAKVVGKPVSACPAETMDQTFYESDDCQRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ97</accession>
    <name>B1KQ97_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323101.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0454"/>
    <dbReference type="EnsemblBacteria" id="ACA84752">
        <property type="protein sequence ID" value="ACA84752"/>
        <property type="gene ID" value="Swoo_0454"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0454"/>
    <dbReference type="eggNOG" id="COG3950">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_450465_0_0_6"/>
    <dbReference type="OMA" id="APWDFVN"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="118"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="606" mass="68134" checksum="8313D84CF9F8A3D0" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQC4</accession>
    <name>B1KQC4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323128.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0481"/>
    <dbReference type="EnsemblBacteria" id="ACA84779">
        <property type="protein sequence ID" value="ACA84779"/>
        <property type="gene ID" value="Swoo_0481"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0481"/>
    <dbReference type="eggNOG" id="COG2959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036381_1_2_6"/>
    <dbReference type="OMA" id="QAIPRHQ"/>
    <dbReference type="OrthoDB" id="2025570at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007470">
        <property type="entry name" value="HemX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38043">
        <property type="entry name" value="PTHR38043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04375">
        <property type="entry name" value="HemX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="383" mass="43524" checksum="1C531704EB341A44" modified="2008-04-29" version="1">MDNKELDENLQEPKREIVSEEKAQALNISKSTDETSSPTPQSDSRSSGVSWGFLFNLVLILLLTFVTLGGGYYLHQELTKQTDRAQNLAQELRLALKEPSNQISRLDQEQRQAQAQLSQELENLNATQLKLNDRVAKLAQRNPNHWMAEEAKYLVRMAGSKLWLEKDPSTAVSLLKAADQRIESMKDPSLTPLRKALAQDIAQVSVIKSTDIAGTVLMLDSMIENLDKLPLNRADLINAANMVDNSKMTESIDDWQSNLAKSWQALMDDFVVVRKRTTDVTPLLKPDEQWYLVENIRNKLLQSQLALYRQDEVNYRQSLTLARKWIYQYFDLKNTQTEEALAALDALSTLEIQTPKIQQFSSTPLLQQLVIHGNLMISEEPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQH1</accession>
    <name>B1KQH1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">5'-Nucleotidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1926</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a nucleoside 2',3'-cyclic phosphate + H2O = a nucleoside 3'-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19621"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:66949"/>
            <dbReference type="ChEBI" id="CHEBI:66954"/>
            <dbReference type="EC" id="3.1.4.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 3'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10144"/>
            <dbReference type="ChEBI" id="CHEBI:13197"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.1.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1926"/>
    <dbReference type="EnsemblBacteria" id="ACA86210">
        <property type="protein sequence ID" value="ACA86210"/>
        <property type="gene ID" value="Swoo_1926"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1926"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_4_1_6"/>
    <dbReference type="OMA" id="EKAQYPM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008663">
        <property type="term" value="F:2',3'-cyclic-nucleotide 2'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008254">
        <property type="term" value="F:3'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07410">
        <property type="entry name" value="MPP_CpdB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041827">
        <property type="entry name" value="CpdB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="8">
        <location>
            <begin position="38"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="9">
        <location>
            <begin position="382"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="687" mass="74899" checksum="34374C52EBA2778D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQN0</accession>
    <name>B1KQN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase, TatD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324615.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1985"/>
    <dbReference type="EnsemblBacteria" id="ACA86269">
        <property type="protein sequence ID" value="ACA86269"/>
        <property type="gene ID" value="Swoo_1985"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1985"/>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_4_0_6"/>
    <dbReference type="OMA" id="PNEAPRI"/>
    <dbReference type="OrthoDB" id="915852at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="29461" checksum="FA4C26B01E293B01" modified="2008-04-29" version="1">MLIDSHCHLDRLKAAPDQQSLRDILAQAKSRGVDYFLCVNVRQQGFASMRDKMAEFDQVFLSAGVHPLDVQEGLNRVELNEFVKDPKVVAIGETGLDYFYANETKALQQSCFEEQIALAVEVNKPLIIHTRDAREDTINFLKNGHADKVGGVLHCFTESWEMAKAAIDLGFYISVSGIATFKNAGELRTVMRKVPKDRLLVETDSPYLAPVPHRGKENQPAYVRDVAEFIAELRGESYEELAEYTTNNFFNLFSDAAKLVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQQ5</accession>
    <name>B1KQQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coenzyme F390 synthetase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324640.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2010"/>
    <dbReference type="EnsemblBacteria" id="ACA86294">
        <property type="protein sequence ID" value="ACA86294"/>
        <property type="gene ID" value="Swoo_2010"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2010"/>
    <dbReference type="eggNOG" id="COG1541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035301_1_2_6"/>
    <dbReference type="OrthoDB" id="839891at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="186"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="50381" checksum="6521491FDE1A2D80" modified="2008-04-29" version="1">MALVNNSKTSCNTLGNHSHSNAAYGQYTQHLQLLNSYQSNFSISDDSIITQLNDAIRYATSYSPFYIDNASWHEVDTIEAFQHLPFTSKADVKSCYPFNLLAVDFSNIIRYGESTGTSGQYSSGFVTKNDWLSNNLEVCLSWGKILSNQDILAVAVPYELTYVGADIDRVAEILNVTVVSIGTNNILCPWTRLVNLIKTYSITTLFCSPTRAIRLAQLATEAGLDPKSSTVNKIICVGEPSSSAKQKFIAESWNAKVYNHYGMTEALAVATPCEKQKLHLCSNRLFSETLSPKTGSPVPLGEMGELVFTTLNTEAMPLIRYKTGDLIRLDHEPCSCGNPHPTFTHLGREDDIFEAPDGLHHFSELDTVLFSIQGLEPYFSYTVTNNQTLSISAFHTQTNTEDKSLTAERIRTEIRKTFDIEANVSVSNNNEMLEIIDNCSKPGTAIPSSPLMSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQS5</accession>
    <name>B1KQS5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3413</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326016.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3413"/>
    <dbReference type="EnsemblBacteria" id="ACA87681">
        <property type="protein sequence ID" value="ACA87681"/>
        <property type="gene ID" value="Swoo_3413"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3413"/>
    <dbReference type="eggNOG" id="COG1146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_0_0_6"/>
    <dbReference type="OMA" id="DRMLYIH"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000813">
        <property type="entry name" value="7Fe_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022569">
        <property type="entry name" value="Fd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11953">
        <property type="entry name" value="DUF3470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00354">
        <property type="entry name" value="7FE8SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="107" mass="11899" checksum="1FA3A1D7EC4D7751" modified="2008-04-29" version="1">MAFVVTDNCIRCKYTDCVAVCPVDAFHEGPNFLAINPDVCIDCELCVPECAAAAIFQEDALPEGMEQYLELNAELAQIWPVITEVIDAPLDAEQWDGVEDKREHLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQZ5</accession>
    <name>B1KQZ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326085.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3485"/>
    <dbReference type="EnsemblBacteria" id="ACA87751">
        <property type="protein sequence ID" value="ACA87751"/>
        <property type="gene ID" value="Swoo_3485"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3485"/>
    <dbReference type="eggNOG" id="COG5642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123925_1_0_6"/>
    <dbReference type="OMA" id="MRVRRYL"/>
    <dbReference type="OrthoDB" id="1850771at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="137" mass="15625" checksum="C823589477F1DF9C" modified="2008-04-29" version="1">MSNANVQHQHIDIHSAHASKVGFDAAVTILQHWGCKTEAITNILRVNRSSYFAYKSGKKAFILDKDQLTRISYILNIHAALRQFFTNPENIYGYMSMINHNPYFEGRKPLEIIEAGDFGALHEVYNRVDQLRSGGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR64</accession>
    <name>B1KR64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IucA/IucC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IucA/IucC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323229.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0585"/>
    <dbReference type="EnsemblBacteria" id="ACA84881">
        <property type="protein sequence ID" value="ACA84881"/>
        <property type="gene ID" value="Swoo_0585"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0585"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_315653_0_0_6"/>
    <dbReference type="OMA" id="MLHEWFH"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019432">
        <property type="entry name" value="Acyltransferase_MbtK/IucB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007310">
        <property type="entry name" value="Aerobactin_biosyn_IucA/IucC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022770">
        <property type="entry name" value="FhuF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037455">
        <property type="entry name" value="LucA/IucC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34384">
        <property type="entry name" value="PTHR34384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06276">
        <property type="entry name" value="FhuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04183">
        <property type="entry name" value="IucA_IucC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01006">
        <property type="entry name" value="AlcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlcB" evidence="3">
        <location>
            <begin position="750"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="925" mass="105493" checksum="7B3CA2E00FA2C483" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRG8</accession>
    <name>B1KRG8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidinol dehydrogenase</fullName>
            <shortName evidence="5">HDH</shortName>
            <ecNumber evidence="5">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisD</name>
        <name evidence="12" type="ordered locus">Swoo_2091</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6 11">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324720.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2091"/>
    <dbReference type="EnsemblBacteria" id="ACA86375">
        <property type="protein sequence ID" value="ACA86375"/>
        <property type="gene ID" value="Swoo_2091"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2091"/>
    <dbReference type="eggNOG" id="COG0141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006732_3_0_6"/>
    <dbReference type="OMA" id="MVTGPGN"/>
    <dbReference type="OrthoDB" id="935289at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="2 5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5 7">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 7">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA86375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="46207" checksum="93EB77D26953E644" modified="2008-04-29" version="1">MEIFNWSQLTQSEQQAALARSPLVGDADMEQNVLDIINRVQADKDAALADFNLKFDGIKTQSLKLCVDEIEAASSRVSSEIKQAITQAITNINAFHKAQAFTPVEVETQAGVRCELRSEAIEKVGLYIPGGSAPLISTVLMLALPAQIAGCQQRVLVSPPPIDDAIIYAAQECGITDIFQVGGAQAIAAMAFGTETIPAVDKIFGPGNRYVTEAKRLVSQDSRCVVSIDMPAGPSEVLVIADSDANPDFIAADLLSQAEHGPDSQVMLVTDSLLLSEQVNASLKQQLAQLSRWEIAVTALSASRILLVSNMDEAVQVSNRYGPEHLIIQTQAPRELLNKVRAAGSVFLGAYTPESVGDYASGTNHVLPTYGYSRAVSSLSLADFSRRFTVQELSADGLQGLGQTVMTLAAAEQLDAHKNAIAIRLASLAGENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRK3</accession>
    <name>B1KRK3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_3504</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326101.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3504"/>
    <dbReference type="EnsemblBacteria" id="ACA87768">
        <property type="protein sequence ID" value="ACA87768"/>
        <property type="gene ID" value="Swoo_3504"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3504"/>
    <dbReference type="eggNOG" id="COG1032">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018720_0_0_6"/>
    <dbReference type="OMA" id="SDGRWNK"/>
    <dbReference type="OrthoDB" id="973846at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="2">
        <location>
            <begin position="156"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="3">
        <location>
            <begin position="359"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="646" mass="72998" checksum="F0ACB838FA8FDD9A" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRL8</accession>
    <name>B1KRL8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326116.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3519"/>
    <dbReference type="EnsemblBacteria" id="ACA87783">
        <property type="protein sequence ID" value="ACA87783"/>
        <property type="gene ID" value="Swoo_3519"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3519"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_26_6"/>
    <dbReference type="OMA" id="ITYVNAR"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="243"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="321"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="514" mass="56070" checksum="BD124B6FD2ABDBA5" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRM3</accession>
    <name>B1KRM3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trimethylamine N-oxide reductase system, TorE protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3524"/>
    <dbReference type="EnsemblBacteria" id="ACA87788">
        <property type="protein sequence ID" value="ACA87788"/>
        <property type="gene ID" value="Swoo_3524"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3524"/>
    <dbReference type="eggNOG" id="COG4459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_200276_1_0_6"/>
    <dbReference type="OMA" id="YGLIIWI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010649">
        <property type="entry name" value="NapE_TorE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06796">
        <property type="entry name" value="NapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="73" mass="7968" checksum="AE26CB25E1CAE1CC" modified="2008-04-29" version="1">MLYISVIEDKITLRESVMADHLPTETPAEVKSKELKALGFIIVLLFPILTISGIGAYGLIIWIIQAFAGVASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRM9</accession>
    <name>B1KRM9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326127.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3530"/>
    <dbReference type="EnsemblBacteria" id="ACA87794">
        <property type="protein sequence ID" value="ACA87794"/>
        <property type="gene ID" value="Swoo_3530"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3530"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_7_6"/>
    <dbReference type="OMA" id="DCANMSL"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767329" evidence="7">
        <location>
            <begin position="25"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="162"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="394" mass="39405" checksum="7DDB6A46AB860942" modified="2008-04-29" version="1" precursor="true">MYPSPIASAITLALAGTAHLTVMAETAPTNSSSSLNNIHNQCIVQMQSNLHADEVTGLAKNMLKRANMTLSNPAKLTHIYKHSIKGFTITMPCSAAQKAFGDDNTVSSFTPDSIVSISKGKPTNPGNGGGGGDTDNGVPQSTPWGINRVGGPVDGTGRTAWVLDTGIDLNNADLNVDTSKGFSAFTKGKNAGMNDGHGHGTHVAGTIAAIDNSIDVVGVAAGATVVPVKVLDSRGSGSTSGVIAGIDHVAANATAGDCANMSLGGGVSSSLDEAVRAAASNGIFFVLAAGNSGAHASNHSPARANGANIFTISATDSSDNMPSWSNWGNPPVDYAAPGVGISSLKRGGGVTTMSGTSMASPAACGVIMMTGGQPNSDGSAGNDPDNNPDPIIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCW8</accession>
    <name>B1KCW8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microbial collagenase</fullName>
            <ecNumber evidence="2">3.4.24.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.24.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322692.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0042"/>
    <dbReference type="MEROPS" id="M09.001"/>
    <dbReference type="EnsemblBacteria" id="ACA84343">
        <property type="protein sequence ID" value="ACA84343"/>
        <property type="gene ID" value="Swoo_0042"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0042"/>
    <dbReference type="eggNOG" id="COG1512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_462227_0_0_6"/>
    <dbReference type="OMA" id="NHEYVHY"/>
    <dbReference type="OrthoDB" id="43759at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002169">
        <property type="entry name" value="Peptidase_M9A/M9B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01752">
        <property type="entry name" value="Peptidase_M9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00931">
        <property type="entry name" value="MICOLLPTASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764692" evidence="1">
        <location>
            <begin position="22"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="587" mass="67169" checksum="CDF4643E2184583A" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD00</accession>
    <name>B1KD00_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0028"/>
    <dbReference type="EnsemblBacteria" id="ACA84329">
        <property type="protein sequence ID" value="ACA84329"/>
        <property type="gene ID" value="Swoo_0028"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0028"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100967_0_0_6"/>
    <dbReference type="OMA" id="VMARRAH"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="39"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="25727" checksum="6D36C2EF5472BCBD" modified="2008-04-29" version="1">MKLVLLPGMDGTGELFSSLLFSLSEYECEVIALPQTGPQDYASITEYVKEKLPQNDFILVAESFSGPVAARLAKEGAEHLQGVIFVATFLSKPHWLLLSIARALPLKLLSALPFAKLFVKALFLGSAASNELVEQFQSIVDSLPPRVIKARLSSMLSLSFSAELIELPVGYIQATSDYLVSSNKVTEFSACFRELQVRSVEGPHFILQANPAKSAEVISELVTLFGKQTGKGRVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD04</accession>
    <name>B1KD04_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_0050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322700.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0050"/>
    <dbReference type="EnsemblBacteria" id="ACA84351">
        <property type="protein sequence ID" value="ACA84351"/>
        <property type="gene ID" value="Swoo_0050"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0050"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_20_6"/>
    <dbReference type="OMA" id="WTAKKEY"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="240"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="399"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="547"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA84351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="810" mass="92034" checksum="7857D00ABC2E11F7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD57</accession>
    <name>B1KD57_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326225.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3628"/>
    <dbReference type="EnsemblBacteria" id="ACA87892">
        <property type="protein sequence ID" value="ACA87892"/>
        <property type="gene ID" value="Swoo_3628"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3628"/>
    <dbReference type="eggNOG" id="ENOG502ZB8J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_815584_0_0_6"/>
    <dbReference type="OMA" id="YAIWLET"/>
    <dbReference type="OrthoDB" id="1171951at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="375" mass="42714" checksum="889339A7099BDB16" modified="2008-04-29" version="1" precursor="true">MLNRWLNPRALVSLSILLCLIVMLVTSVLMFAKNHYMPVAMLHTVLGFSLLLFAILHLKNNFSPLKSYLSLKFWGKKSRYKASFPLVLFLGASLIGLSWYGYGPIKRFYQWGMELRVADTFGEAPSYQYIVVDKTDKSLSGQELTIELRTGDSFLWPQYAIWLETMEGELVQPLYVTSKLAKNNFENRVTKLDESTVFKDNPFSTADFKMEDAFNLVVEPESKSERVRPESLPVFLHQLGIRDEEGQFVTHGENLIPDAYTGATMSDNFVYRTKLESELSGRYRLKLEMNQSFDFNQYYSSDRFPSDPIYSGSGFSAQPSVVYETTLNFDNPERLYLMGLAGRGHHSGQDGDIHSDLSGMDSALSIVDRVIVEVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD64</accession>
    <name>B1KD64_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain-fatty-acid--luciferin-component ligase</fullName>
            <ecNumber evidence="2">6.2.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.19" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326232.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3637"/>
    <dbReference type="EnsemblBacteria" id="ACA87899">
        <property type="protein sequence ID" value="ACA87899"/>
        <property type="gene ID" value="Swoo_3637"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3637"/>
    <dbReference type="eggNOG" id="COG1541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051326_1_0_6"/>
    <dbReference type="OMA" id="QVELNTC"/>
    <dbReference type="OrthoDB" id="839891at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047474">
        <property type="term" value="F:long-chain fatty acid luciferin component ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008218">
        <property type="term" value="P:bioluminescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007534">
        <property type="entry name" value="LuxE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016671">
        <property type="entry name" value="LuxE_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04443">
        <property type="entry name" value="LuxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016580">
        <property type="entry name" value="Acyl-protein_synthetase_LuxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LuxE" evidence="1">
        <location>
            <begin position="6"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="382" mass="44196" checksum="E1279288B8C81457" modified="2008-04-29" version="1">MAILKPIEKCDIIASSEIDDLIFMSSPQEWTFEEQKEIQDRLVRESFDYHYNRNEDYRQYCITQHINENILSIDDIPVYPTSVFKHLRLHTANESEIENWYTSSGTSGVKSHIARDRLSIERLLGSVNFGMKYVGDWFDHQMELVNLGPDRFNTNNVWFKYVMSLVELLYPTEFTVDDDQIDFKKTVDSLFRIHSTTKDICLIGPPYFIFLLCQYMKENRIELNAGTRLHIITGGGWKSNQSESLNRHDFNQMLMGTFHLANENQIRDTFNQVELNTCFFEDKFQRKHVPPWVYARALDPVTLKPVPEGEQGLLSYMDASSTGYPAFIITDDIGTVQHIKAPDPYPGTTIEIIRRLSTRAQKGCALSMSNSIKGKATLRMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD70</accession>
    <name>B1KD70_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326238.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3643"/>
    <dbReference type="EnsemblBacteria" id="ACA87905">
        <property type="protein sequence ID" value="ACA87905"/>
        <property type="gene ID" value="Swoo_3643"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3643"/>
    <dbReference type="eggNOG" id="ENOG50335AU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2221432_0_0_6"/>
    <dbReference type="OMA" id="ERVFWHL"/>
    <dbReference type="OrthoDB" id="1634299at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="110" mass="13004" checksum="4088C467C8303412" modified="2008-04-29" version="1">MTPNEFIDNKAPQLAQYGKAFLSNQLDFNEVQLYLWDTLEEWQQFNHQGDAQTDMERVFWHLLHAFDKWPDWMIRGNQYLRKQIDECCDFLSIGGQIPKGCIGIRPSLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD87</accession>
    <name>B1KD87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3660</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326255.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3660"/>
    <dbReference type="EnsemblBacteria" id="ACA87922">
        <property type="protein sequence ID" value="ACA87922"/>
        <property type="gene ID" value="Swoo_3660"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3660"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_10_3_6"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032158">
        <property type="entry name" value="DUF4994"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16385">
        <property type="entry name" value="DUF4994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005661814" evidence="4">
        <location>
            <begin position="25"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="44"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4994" evidence="6">
        <location>
            <begin position="417"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA87922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="523" mass="57642" checksum="2EE2AFB50F2C1B65" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD91</accession>
    <name>B1KD91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMP-30/Gluconolaconase/LRE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326259.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3664"/>
    <dbReference type="EnsemblBacteria" id="ACA87926">
        <property type="protein sequence ID" value="ACA87926"/>
        <property type="gene ID" value="Swoo_3664"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3664"/>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_3_1_6"/>
    <dbReference type="OMA" id="WTDIEGA"/>
    <dbReference type="OrthoDB" id="852341at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="1">
        <location>
            <begin position="24"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="304" mass="33945" checksum="9CBA91A3451ADBC6" modified="2008-04-29" version="1">MQLDNESNEVTAKFLYSVPVANQLGEGVIWDTLSQQVWWTDIEGKMLYAFEPQSHKLSQWHMPERLCSFALTETKGLILAAFASGFALYRFEGKGPEIEWLARPELSLQENRMNDGRVDAKGRFWCGSMVEEETAQGDTGSLYCINKGQCQWQGDGYQILNGLAWSLDNRWLYCADSAKNRIYRHSFDAKEASLGPVETFATTAEHIHPDGSTVDSDGSLWSAQWGGGRVVRYSVDGDIQFILKLPVSQPSCVAFGGEQMNLLFVTTAREGLSSQQLNSQALAGDLLVYQLRGVRGLPTPHYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDD4</accession>
    <name>B1KDD4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0639</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323282.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0639"/>
    <dbReference type="EnsemblBacteria" id="ACA84935">
        <property type="protein sequence ID" value="ACA84935"/>
        <property type="gene ID" value="Swoo_0639"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0639"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_10_0_6"/>
    <dbReference type="OMA" id="LYADSFH"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="455" mass="48188" checksum="B0471E861D323F6C" modified="2008-04-29" version="1" precursor="true">MANNGLSKTEKKVAFSLASVFGLRMMGLFMIMPVFALYGQHLQGFSPLWVGIAIGAYGLTQAILQIPMGMLSDKFGRKPIILIGLLMFAFGSLVAANADTIYGVVAGRAIQGMGAIAAAVLALAADLTRDEQRTKVMAIIGMCIGFSFALSLLVGPIVAQYLGLSGLFAMTAGLAVLGMIIVQLLVPNPISQAPKGDTLATPAKLKAMVTDPQLFRLDAGIFILHLVLTAVFVALPLDLVDAGLAKEKHWMLYFPAFMGAFFLMVPLIIIGVKKKNTKATFQVSLLIMMLALASMALFANNLVVLSIAVVLFFTGFNYLEASLPSLIAKFCPVGDKGSAMGVYSTSQFLGAFCGGILGGGAYQLVGAEGVFAVALGLMTLWLLLTLGMKNPVLLKSYTLEAKVEGKEQAKVMATELSQLAGVAEAIVVLEEKVAYLKVDEHFDLREARAVLGSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDN8</accession>
    <name>B1KDN8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UvrABC system protein C</fullName>
            <shortName evidence="7">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">uvrC</name>
        <name evidence="11" type="ordered locus">Swoo_2151</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the UvrC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2151"/>
    <dbReference type="EnsemblBacteria" id="ACA86435">
        <property type="protein sequence ID" value="ACA86435"/>
        <property type="gene ID" value="Swoo_2151"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2151"/>
    <dbReference type="eggNOG" id="COG0322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014841_3_0_6"/>
    <dbReference type="OMA" id="HIECFDN"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 7" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="9">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="8">
        <location>
            <begin position="202"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="10">
        <location>
            <begin position="252"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA86435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="609" mass="68504" checksum="EB0A50EB1BB24988" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE26</accession>
    <name>B1KE26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0111 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323359.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0717"/>
    <dbReference type="EnsemblBacteria" id="ACA85012">
        <property type="protein sequence ID" value="ACA85012"/>
        <property type="gene ID" value="Swoo_0717"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0717"/>
    <dbReference type="eggNOG" id="COG1392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104916_0_1_6"/>
    <dbReference type="OMA" id="WVGDLAD"/>
    <dbReference type="OrthoDB" id="1837604at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002727">
        <property type="entry name" value="DUF47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36536">
        <property type="entry name" value="PTHR36536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00153">
        <property type="entry name" value="TIGR00153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="226" mass="25506" checksum="5826A5FEDA4B3A5C" modified="2008-04-29" version="1">MPVNSILGVFAKSPIKPLQEHIDKVHQCASILVPFFDATASGDWSGAAEIRQQINVTEREADSLKREIRLTLPGGLFMPVERTDLLELLTQQDKIANKAKDISGRILGRELLIPEAIQEPFKAYLQRCLDAVTQAKQAINELDDLLETGFRGREVDLVAKMIVELDKIEEDTDDLQISIRRQLFAIENDLNPIDVMFLYKIIEWVGDLADLAERVGSRLELMLARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER6</accession>
    <name>B1KER6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative V10 pilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326412.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3822"/>
    <dbReference type="EnsemblBacteria" id="ACA88081">
        <property type="protein sequence ID" value="ACA88081"/>
        <property type="gene ID" value="Swoo_3822"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3822"/>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098637_3_3_6"/>
    <dbReference type="OMA" id="EPYFLIG"/>
    <dbReference type="OrthoDB" id="1582722at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="17324" checksum="A2EB2B03A6384703" modified="2008-04-29" version="1">MLRHDNGFTLIELVVVIIILGVLSVIAAPKFISLNKDAKVAVLEGARGALSTANSFSYSKAALQGQELVDASSANIDMDSDGTADLIGYYGLIKFVISAKEYAGLDEDLTISKHYGGSGPTLPYFLISFTDNPASAVTQCFLSVYYPDTAGGSVTYEFVTEDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KER8</accession>
    <name>B1KER8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3824</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326414.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3824"/>
    <dbReference type="EnsemblBacteria" id="ACA88083">
        <property type="protein sequence ID" value="ACA88083"/>
        <property type="gene ID" value="Swoo_3824"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3824"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_403290_0_0_6"/>
    <dbReference type="OMA" id="NWNNVLQ"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766506" evidence="3">
        <location>
            <begin position="18"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="488"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA88083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="659" mass="75470" checksum="B1BA36A8CFB80E66" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEX2</accession>
    <name>B1KEX2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0828"/>
    <dbReference type="EnsemblBacteria" id="ACA85123">
        <property type="protein sequence ID" value="ACA85123"/>
        <property type="gene ID" value="Swoo_0828"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0828"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_28_6"/>
    <dbReference type="OMA" id="EVANRRC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="27"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="185"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="324" mass="36642" checksum="7D4C9917C703E03A" modified="2008-04-29" version="1">MDEYLNTGLSIKDVNEPQFVIKEDLDKILIIDDARDNRALLSELLMPEYKVLLAKDGVQGLNLACKHSPDLILLDVIMPGINGYQVIKSLKSDESTMDIPVIFISSKISTEDEKIGLDLGAVDYITKPFHPPIVQARVRNHLLGQRHKNLLEQLALVDSLTEVYNRRFYELDIRKVWSACNRNDTELSIAMIDIDFFKSYNDDYGHLSGDNALRLVASHIKKQLKRPHDVIARYGGEEFAIILPNTNAESARNLLSNICRSVENLQVEHDSSSISHYLTISVGGASTIPSRDADHESFLKVVDEHLYQAKAQGRNKVCWKESRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF54</accession>
    <name>B1KF54_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324937.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2316"/>
    <dbReference type="EnsemblBacteria" id="ACA86595">
        <property type="protein sequence ID" value="ACA86595"/>
        <property type="gene ID" value="Swoo_2316"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2316"/>
    <dbReference type="eggNOG" id="COG3122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098678_2_1_6"/>
    <dbReference type="OMA" id="EMNRITV"/>
    <dbReference type="OrthoDB" id="1467864at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018636">
        <property type="entry name" value="DUF2058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09831">
        <property type="entry name" value="DUF2058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="180" mass="20697" checksum="8E54DA1D269473E6" modified="2008-04-29" version="1">MANPFQEQLLKAGLVSKQKVQKAKTQKRRDRKAKVDDGSAELKQQIAEQKQAQAAKDKALNEQRFEAASEKGLVRGLVTEFKRLAIKTPQNAEVKFNYTFENKIFSLYVDDKLQSQLLNGQLGIVRHEQSSYLVPHKLAERVNLLVPEWCGYLWVQDDTSQVVEEDDPYADYVIPDDLMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF87</accession>
    <name>B1KF87_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324970.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2349"/>
    <dbReference type="EnsemblBacteria" id="ACA86628">
        <property type="protein sequence ID" value="ACA86628"/>
        <property type="gene ID" value="Swoo_2349"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2349"/>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_993759_0_0_6"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="225" mass="26405" checksum="06C22521D8CB5DE3" modified="2008-04-29" version="1">MDKNNQFVKMPIMTASGTVFGYEVLLREFNGISLDTFNRYPELYTEFCFEILSVISSLDNYHKIRQKGESLFINLTLDQLLSDGALTFLNQFYRSDSKVDDVIIEITENEMLYQNTAMLQERILLFRALGYQFAIDDFGVEHSNFQRVFDIRPDFIKLDSKMVITYSEQEQLNPAFKHLIDFCHQINTQVIAEGIESEKTYKRLTLDKVDYFQGYLFGQPQRLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFP7</accession>
    <name>B1KFP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323560.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0920"/>
    <dbReference type="EnsemblBacteria" id="ACA85213">
        <property type="protein sequence ID" value="ACA85213"/>
        <property type="gene ID" value="Swoo_0920"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0920"/>
    <dbReference type="eggNOG" id="ENOG502ZEEE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2355560_0_0_6"/>
    <dbReference type="OMA" id="WDARSMG"/>
    <dbReference type="OrthoDB" id="2059548at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="96" mass="10883" checksum="9B20267670FA0F22" modified="2008-04-29" version="1">MFPYPEQYRQAAPPILTAFMVFWSLLSRLILGGSSSIAFYPLFGLFPLVILLHGQLIWQAKGMERLDQGVYAFIHIALSFVVWTFSLMHVNGNGFS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFS0</accession>
    <name>NAGB_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="1">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GlcN6P deaminase</fullName>
            <shortName evidence="1">GNPDA</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nagB</name>
        <name type="ordered locus">Swoo_0943</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323583.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KFS0"/>
    <dbReference type="SMR" id="B1KFS0"/>
    <dbReference type="STRING" id="392500.Swoo_0943"/>
    <dbReference type="EnsemblBacteria" id="ACA85236">
        <property type="protein sequence ID" value="ACA85236"/>
        <property type="gene ID" value="Swoo_0943"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0943"/>
    <dbReference type="eggNOG" id="COG0363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049611_0_1_6"/>
    <dbReference type="OMA" id="FNEPCSS"/>
    <dbReference type="OrthoDB" id="1828393at2"/>
    <dbReference type="UniPathway" id="UPA00629">
        <property type="reaction ID" value="UER00684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="PTHR11280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000139792" description="Glucosamine-6-phosphate deaminase">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for enolization step" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for ring-opening step" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01241"/>
        </source>
    </evidence>
    <sequence length="264" mass="28647" checksum="E9E35229D1110C2B" modified="2008-04-29" version="1">MQIVILKNSAEVAEYGANIFKKQLQSKPDSVLGLATGSTPVSLYQGLIEANKLGDISFKEVTSFNLDEYLGLAGTHPQSYRYFMNEQLFDHIDIDKANTHVPPGDAENPIQACDGYEEQIQAAGGIDIQLLGIGRNGHIGFNEPSSGLMSRTRVKTLTKATIEDNARFFKEDEYQPHLSITMGIGTILDAKKVVLLATGENKADAILATVEGALTASCPASALQLHKNAVLVIDEAAASKLSDRDFYKHIEAENQKLLARLAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFT5</accession>
    <name>B1KFT5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain containing membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323598.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0958"/>
    <dbReference type="EnsemblBacteria" id="ACA85251">
        <property type="protein sequence ID" value="ACA85251"/>
        <property type="gene ID" value="Swoo_0958"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0958"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_9_1_6"/>
    <dbReference type="OMA" id="QWELHYL"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="83"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="140" mass="15626" checksum="639B969F8A030A7D" modified="2008-04-29" version="1">MNVRDIMSTQLVCISDEANLKDAHSLMQNRGVRHLPVISESDGKLVGILTHKKMISTVMSMIYKYGADALDRKERNQGIQPLMESDFQRLAQDEPLAIVVEYFIDNKLGCLPVVDSEGKIEGIVTSSDFVKLCAELLKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFW0</accession>
    <name>B1KFW0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323623.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0983"/>
    <dbReference type="EnsemblBacteria" id="ACA85276">
        <property type="protein sequence ID" value="ACA85276"/>
        <property type="gene ID" value="Swoo_0983"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0983"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056368_0_0_6"/>
    <dbReference type="OMA" id="HEFYFGL"/>
    <dbReference type="OrthoDB" id="1560847at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764833" evidence="1">
        <location>
            <begin position="35"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="402" mass="46546" checksum="1C511B730AE6AC15" modified="2008-04-29" version="1" precursor="true">MKSFSSNFCCVKPSLYKSSLLFICLILISLQACTSTSNTAHVSQIEQYFYDEHFVEVDGLPQPDELFSLPDDAIRELRTELQRAKLTKSNNMLANEWLAEYINAEEGAFQYRDNMTRVASETFSERAGNCLSLVLLTSALAQELGVEVEFQEIEVPPVWDKQGDFYLVNGHINLRLLPLSHGDTVHMLKRAIQVDFLPERAVRGFDKKRINKKTVTAMFYNNVAAESLVMGDYDKAYGFLKLGLQAMPSYMPALNTLAVLYRYKGLNQEAETLYKLALEIDNYDMNALYNYAVMLGAQDRLEEWAAVHKRLELERIDNPYYYYDMAQQAYFDKEYQDALLWYKRAVAKADYRHEFYFGLSRAYWQTGDERRAQANMKKALNLSNDENNKLKYQSKLHAMKSH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFY6</accession>
    <name>TTCA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-cytidine(32) 2-sulfurtransferase</fullName>
            <ecNumber evidence="1">2.8.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Two-thiocytidine biosynthesis protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA 2-thiocytidine biosynthesis protein TtcA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ttcA</name>
        <name type="ordered locus">Swoo_2415</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + ATP + cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] = 2-thiocytidine(32) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[cysteine desulfurase]</text>
            <dbReference type="Rhea" id="RHEA:57048"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:12157"/>
            <dbReference type="Rhea" id="RHEA-COMP:12158"/>
            <dbReference type="Rhea" id="RHEA-COMP:14821"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:141453"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:57049"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TtcA family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325035.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KFY6"/>
    <dbReference type="SMR" id="B1KFY6"/>
    <dbReference type="STRING" id="392500.Swoo_2415"/>
    <dbReference type="EnsemblBacteria" id="ACA86693">
        <property type="protein sequence ID" value="ACA86693"/>
        <property type="gene ID" value="Swoo_2415"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2415"/>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026481_0_0_6"/>
    <dbReference type="OMA" id="MNLDQKQ"/>
    <dbReference type="OrthoDB" id="1051352at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01850">
        <property type="entry name" value="TtcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012089">
        <property type="entry name" value="tRNA_Cyd_32_2_STrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000348847" description="tRNA-cytidine(32) 2-sulfurtransferase">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="PP-loop motif" evidence="1">
        <location>
            <begin position="45"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01850"/>
        </source>
    </evidence>
    <sequence length="319" mass="35621" checksum="00EBB9E33882AAF6" modified="2008-04-29" version="1">MSVDLSAQQVTRMKKLQKKIRSEVGKAISDYNMVEEGDRIMCCLSGGKDSYAMLDILLDLQQRAPIKFEIVAVNLDQKQPGFPEHVLPAYLDSLGVAYHILEKDTYSIVRDKIPEGQKTCSLCSRLRRGTLYGFAQKIGATKIALGHHRDDIIETLFLNMFFAGKQKAMPPKLLSDDGANMVIRPLAYAREKDIAEYAELKGFPIIPCNLCGSQENLKRASVKEMLNQWDVEHPGRIESIFTAMQNTSPSQGVDREQFDFISLTRDANAPLKGEVAESDLPAFDFVDVSNNGHIDLDAASKAKRVNPEHKINIVSTYTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG01</accession>
    <name>B1KG01_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325050.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86708">
        <property type="protein sequence ID" value="ACA86708"/>
        <property type="gene ID" value="Swoo_2430"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2430"/>
    <dbReference type="eggNOG" id="ENOG502ZKFM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073567_0_0_6"/>
    <dbReference type="OMA" id="SRFMNDY"/>
    <dbReference type="OrthoDB" id="689175at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="318" mass="36745" checksum="46F815CE126F2C56" modified="2008-04-29" version="1">MAGERSKSIGEIGESIAENFFSKIGWGSPQKGVYYPCYNKKNHALKASVGGEKHQHGIDFQVSYKSTLESETLNNLLISVKHSKDRQYPKSATKEFKGYISDLVDSMQCFKRSPHYRDISSSHAGCRTINDIPVLFFISSKDNEHYDFTSHLQNSRFMNDYDDVKELYIIDNRKVSFILNVLNYIESHYPDYEWYFFHPSTGMNIGDINIRQHSKQMQIEFLTSPFIPFVLKKKIGDHETCKFFLASIDSFTQDNFSKLVTYCRNNTSDNISDVEISMHDYFLDDNLGDTRKVLSAHDIELDVKVSNYNPSFRSLANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG13</accession>
    <name>B1KG13_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transf_9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325062.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2442"/>
    <dbReference type="EnsemblBacteria" id="ACA86720">
        <property type="protein sequence ID" value="ACA86720"/>
        <property type="gene ID" value="Swoo_2442"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2442"/>
    <dbReference type="eggNOG" id="COG2343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126578_1_1_6"/>
    <dbReference type="OMA" id="YVAFWRG"/>
    <dbReference type="OrthoDB" id="2063459at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_9" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="94" mass="10550" checksum="04906AB82321F2AF" modified="2008-04-29" version="1">MKASWNGAVIARSDKTIVVEGNHYFPPDSINSDYFTPSDFTSHCPWKGHAQYYSVVVDGKINQAAAWCYPETLDAAKEIENYIAFWRGVDVEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG22</accession>
    <name>B1KG22_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325071.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2452"/>
    <dbReference type="EnsemblBacteria" id="ACA86729">
        <property type="protein sequence ID" value="ACA86729"/>
        <property type="gene ID" value="Swoo_2452"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2452"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_6"/>
    <dbReference type="OMA" id="LVYHDIR"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="300" mass="33550" checksum="1082F35BC33E67F3" modified="2008-04-29" version="1">MGQLENMQIFIKVVETGGITKAAEQLNLAKSAVSKRLSEIEKQLSVKLINRTTRKSSLTEAGNAYYQKCKLILEEVDDLNCQISSVQQSLNGALKLAVPLSFGVVHLVKALELFAKQHPSLQMDLDFSDRYIDLVEEGFDLAIRIGTLADSSMHARAIAPISHILCASPEYLALNGSPSTPEQLKSHSLLRYSRMPLAGIELTDKDNKKFTVPMESHCIANNGDFLKAMAVSGHGIAFLPRFIVWQELANGTLESVMQNYQLAQMKAYAVYPQNRYLPKKVRMLIDFLSEHFGETPYWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGF8</accession>
    <name>B1KGF8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ferredoxin--NADP(+) reductase</fullName>
            <ecNumber evidence="5">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0993</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323633.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0993"/>
    <dbReference type="EnsemblBacteria" id="ACA85286">
        <property type="protein sequence ID" value="ACA85286"/>
        <property type="gene ID" value="Swoo_0993"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0993"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_3_0_6"/>
    <dbReference type="OMA" id="MTSEHYW"/>
    <dbReference type="OrthoDB" id="707164at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06195">
        <property type="entry name" value="FNR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033892">
        <property type="entry name" value="FNR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="27611" checksum="1866F2C7476D63F1" modified="2008-04-29" version="1">MWVDGEVIERTDWCDNLFSLKIKASIEPYIAGQFIKLSQIINDKRIGRAYSIVNAPNSEYVEVLAVSVLDGLLSPNLQQLKVGDHIEVSSKAAGFMTLDEVPPQGQDLWLLATGTAVGPFISILETDEPWARFDHIVLVYGVREAKDLAYKEKLLALEKRYPNQFKLLFSVTRESYPNALESRISTALASGEIEQRLGLRLTAEDSQVMLCGNPEMIKDANNILLEKGLSKNLRRAPGQITIEKYW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGH8</accession>
    <name>APAG_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein ApaG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">apaG</name>
        <name type="ordered locus">Swoo_1013</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323653.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KGH8"/>
    <dbReference type="SMR" id="B1KGH8"/>
    <dbReference type="STRING" id="392500.Swoo_1013"/>
    <dbReference type="EnsemblBacteria" id="ACA85306">
        <property type="protein sequence ID" value="ACA85306"/>
        <property type="gene ID" value="Swoo_1013"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1013"/>
    <dbReference type="eggNOG" id="COG2967">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128074_0_0_6"/>
    <dbReference type="OMA" id="YVSGCNL"/>
    <dbReference type="OrthoDB" id="1835593at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00791">
        <property type="entry name" value="ApaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007474">
        <property type="entry name" value="ApaG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036767">
        <property type="entry name" value="ApaG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023065">
        <property type="entry name" value="Uncharacterised_ApaG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04379">
        <property type="entry name" value="DUF525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110069">
        <property type="entry name" value="SSF110069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51087">
        <property type="entry name" value="APAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000133816" description="Protein ApaG">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="ApaG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00791"/>
        </source>
    </evidence>
    <sequence length="126" mass="14152" checksum="1EE0C4827BA75CF1" modified="2008-04-29" version="1">MTELETSIKIDVKTEYIEDQSSPNDERYLFRYTITIINLGKEPVTLKTRYWSITDSNQHLSVVQGAGVVGETPTIEPDTAYQYTSGTVLETPFGVMEGNYGMVTENGEMFKAKIPPFRLSIPGLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGJ4</accession>
    <name>B1KGJ4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_1029</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323669.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1029"/>
    <dbReference type="EnsemblBacteria" id="ACA85322">
        <property type="protein sequence ID" value="ACA85322"/>
        <property type="gene ID" value="Swoo_1029"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1029"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_27_6"/>
    <dbReference type="OMA" id="IDNIAHE"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="147"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="207"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA85322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="420" mass="47624" checksum="5079CCC628B5E48F" modified="2008-04-29" version="1" precursor="true">MKRLFISLYLLISLSILGIGWTLDNIWQNNVEDSGAMDAPLIALAQLLGKLPEQERLDYLKQIDHSPNYPLELVDSSQIALSDHSALTDNSVLITTVSDHFELHFIKVNNQILVAGPIEIDPRARLRKLFTLLFYLSLGLIALIWVWPLSRDLKTLRNATQEFGQAKWDTQIELSPRSQVLPLATTFNEMAKQISSLIESQKHLSNAVSHEIRTPLARLKFALALMPQYCQPDSDEQRRTEFLEEMKLDVKEMENLLQELLTYASLESQQKEVNLEHCDLTALTLQTIKRLSSQSTPPIHFNKGAQPAYIMGDPSLIERAIQNLITNAQRFAQDAIDIKIEQNKQLVTLSVTNDGPGIPKEDQAKIFEPFYRSKSVQNGNKGHGLGLAIIKRIMERHQGEVELISSEEKTSFILTWPNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK4</accession>
    <name>B1KGK4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hpt protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1039</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323678.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1039"/>
    <dbReference type="EnsemblBacteria" id="ACA85332">
        <property type="protein sequence ID" value="ACA85332"/>
        <property type="gene ID" value="Swoo_1039"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1039"/>
    <dbReference type="eggNOG" id="COG2198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2025157_0_0_6"/>
    <dbReference type="OMA" id="IGDEPEM"/>
    <dbReference type="OrthoDB" id="2007322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="3">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="130" mass="14278" checksum="A6639B27CFAB5056" modified="2008-04-29" version="1">MIEPNLKVLNKDIMLDLIGDDPVMIRQFGIDFLKQAKESLQKIILMYNQNSFTAVKEEAHYLKTSAAAVGAEQTSHLLKALEVSGEVGDKQQCKHLILEIKSSLKQVHGAIIDDSSTNSSMPPSQGDNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGR4</accession>
    <name>B1KGR4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4274 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325124.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2506"/>
    <dbReference type="EnsemblBacteria" id="ACA86783">
        <property type="protein sequence ID" value="ACA86783"/>
        <property type="gene ID" value="Swoo_2506"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2506"/>
    <dbReference type="eggNOG" id="ENOG5033BBB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1495602_0_0_6"/>
    <dbReference type="OMA" id="LLYWYGQ"/>
    <dbReference type="OrthoDB" id="1073003at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025369">
        <property type="entry name" value="DUF4274"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14096">
        <property type="entry name" value="DUF4274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4274" evidence="1">
        <location>
            <begin position="66"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="184" mass="21399" checksum="866F9B4E633ADFDD" modified="2008-04-29" version="1">MAKKLTKEQGKRASICFECGCIPSKDVWREAVAEKGKDYDSVMYMAKQFPISECEVITIEELQSIEEIHAVADNYNWDNNCIKSLYAFIDHPLCDAGTALLLFWKGAGYEQLGHHPRFPNEQEKLFFQELVLRFKTKQFNSYKIAFDPYDECYVPTLDDCLQRGYLIPGELFCQYSTMHIDTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGT4</accession>
    <name>B1KGT4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein, VC_A0110 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325144.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2526"/>
    <dbReference type="EnsemblBacteria" id="ACA86803">
        <property type="protein sequence ID" value="ACA86803"/>
        <property type="gene ID" value="Swoo_2526"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2526"/>
    <dbReference type="eggNOG" id="COG3519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028593_2_1_6"/>
    <dbReference type="OMA" id="VPSMTIM"/>
    <dbReference type="OrthoDB" id="140284at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010272">
        <property type="entry name" value="T6SS_TssF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35370">
        <property type="entry name" value="PTHR35370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05947">
        <property type="entry name" value="T6SS_TssF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028304">
        <property type="entry name" value="UCP028304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03359">
        <property type="entry name" value="VI_chp_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="588" mass="67356" checksum="4097590AD3938BCE" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGU3</accession>
    <name>B1KGU3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proteinase inhibitor I11 ecotin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I11 (ecotin) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2535"/>
    <dbReference type="MEROPS" id="I11.001"/>
    <dbReference type="EnsemblBacteria" id="ACA86812">
        <property type="protein sequence ID" value="ACA86812"/>
        <property type="gene ID" value="Swoo_2535"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2535"/>
    <dbReference type="eggNOG" id="COG4574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111565_0_1_6"/>
    <dbReference type="OMA" id="PKAEKGM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036198">
        <property type="entry name" value="Ecotin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005658">
        <property type="entry name" value="Prot_inh_ecotin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35890">
        <property type="entry name" value="PTHR35890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03974">
        <property type="entry name" value="Ecotin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006865">
        <property type="entry name" value="Prot_inh_ecotin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49772">
        <property type="entry name" value="SSF49772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767346" evidence="2">
        <location>
            <begin position="31"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="190" mass="21148" checksum="1CAC351061038A5D" modified="2008-04-29" version="1" precursor="true">MTTPSISFSAKRIITASALALSMLSFNALATSPAHPSGLNQNMITSTAFDSTNYLAEKKTEMFPVPSEGMEQHILTLLPLDNESDYMVEIQIGKTQLVDCNKHGLSGELTENTVKGWGYNYYQVDSINPGPSTMMACFDKAKTEAFLSIPGSLKVNYDSRLPKVFYLPKGSELRYRIWRVESEFNVSKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH17</accession>
    <name>B1KH17_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326658.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4073"/>
    <dbReference type="EnsemblBacteria" id="ACA88329">
        <property type="protein sequence ID" value="ACA88329"/>
        <property type="gene ID" value="Swoo_4073"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4073"/>
    <dbReference type="eggNOG" id="ENOG5032PSD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2345102_0_0_6"/>
    <dbReference type="OrthoDB" id="2217150at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="98" mass="10850" checksum="2638A66041EA57CC" modified="2008-04-29" version="1">MNRLQQKVEMQLPQERALSPQKVITVSALLILLVAVQISTQSVEDWFVFGLNVLEVTAPMNVSVHDVSNVGSSVAGGLEHLREMVWSVVKALVEFIFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHA3</accession>
    <name>B1KHA3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323757.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1118"/>
    <dbReference type="EnsemblBacteria" id="ACA85411">
        <property type="protein sequence ID" value="ACA85411"/>
        <property type="gene ID" value="Swoo_1118"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1118"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_0_6"/>
    <dbReference type="OMA" id="DYWRIPD"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="34298" checksum="C0E50FC5D79BCDBA" modified="2008-04-29" version="1">MGETDYLALDGRLLRLFLTVFDTGSVSGAADKLDLNQSTVSNGLDRLRRIIGEPLFVRSGRGIIPTQEASRLAPLARELLAKFEQFVEAQEYRAEDESRPFVIAANDYERDILLPQLLVKLRLLAPNAPLKVLTAGAKETVLEQLRQGEIDLVLSPSIEANVDDLKQQWLFSDCDAVFYDPEVIKGPIDLAQYVALPHARVVFNYSGRSEIDEVLTGLKLEREIKLEVANFSALSSMMRGSELVTTLPSRVGISLLDKMAQQTPPISLNDINIYQFWHQAYTHSPRHRWLRELVKALAEELPMLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHC1</accession>
    <name>B1KHC1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1136</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1136"/>
    <dbReference type="EnsemblBacteria" id="ACA85429">
        <property type="protein sequence ID" value="ACA85429"/>
        <property type="gene ID" value="Swoo_1136"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1136"/>
    <dbReference type="eggNOG" id="COG0493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_3_4_6"/>
    <dbReference type="OMA" id="ETKMGVR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="493"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="558"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="598" mass="66681" checksum="D4A211D19C0E5A6C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHD0</accession>
    <name>B1KHD0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323784.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1145"/>
    <dbReference type="EnsemblBacteria" id="ACA85438">
        <property type="protein sequence ID" value="ACA85438"/>
        <property type="gene ID" value="Swoo_1145"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1145"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_0_6"/>
    <dbReference type="OMA" id="NPYFTEI"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="333" mass="36843" checksum="49EB15A60B9D7B54" modified="2008-04-29" version="1">MATIYDVSVLAGVSLATVSRVMNKNTNVSEKTKKKVQDAMDQLGYRPSSIAQSLASNRSNSIGVLVSQLDGPFYGPMMTEIETALRDANKHVIIAAGHSNETQEKEAVEFLLDRGCDALILDVEALSDEYIINLCQQSTPIVLINRFISEIEERCIYLNNALGGYLATKHVLSQGHTQLAYIAGPQFKSDARERLEGHKQALAEFEVTFDETLFFEGNFREPSGVSAMEYLLKQDKQFTCVISANDQMASGAIAVSLERDISVPKQLSFIGYDNSPFPKYISPKLSTVSNPIQEMGKMAALWVLKNVYNKPDLSIVNTFTPQLILRDSVKSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHN2</accession>
    <name>B1KHN2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2640</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325257.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2640"/>
    <dbReference type="EnsemblBacteria" id="ACA86917">
        <property type="protein sequence ID" value="ACA86917"/>
        <property type="gene ID" value="Swoo_2640"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2640"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_14_0_6"/>
    <dbReference type="OMA" id="YCQYYSV"/>
    <dbReference type="OrthoDB" id="1217595at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="10"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="424" mass="47569" checksum="17A3A9B18D000F50" modified="2008-04-29" version="1" precursor="true">MDNQQRRAYLALTLATLAFAACFSVWTLYSIIGIELKERLALSATEFGFLLAAPIFTGAIFRVPIGFLAEKFSCRNLFFWQMLLAVPPLFYLPQIETYSGYIWIGFVLGLTGVSFTIGIRYVTDWFETKRQGFALGVFGAGNAGAAITLVLVPIIVDTFGWQQIGYAYGIGMIFMAILFRLFAPEVNRYYRKQRDSHDLAFHLAPLKDLQVWRFGLYYYFVFGSFLALILWLPHYYVSAYGLSLTQSMALTLLFVTSSSMIRAVGGWFADTYGAKAVNWTAFWICMVCLFFLSYPPTTMIIHGVEKNVEVSFEVNVWLFTLLIFVIGIAQGFGRASVYKTIYDHYPHHMGSVGGIVAAIGALGGCTLPILFGFAVDIIGVYSACFMLLYGVLAACMVVMYLALRAERHQKLLRDAIANNFLEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHQ1</accession>
    <name>B1KHQ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrolase (Secreted protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325276.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2660"/>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86936">
        <property type="protein sequence ID" value="ACA86936"/>
        <property type="gene ID" value="Swoo_2660"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2660"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058767_0_0_6"/>
    <dbReference type="OMA" id="FQLEPWT"/>
    <dbReference type="OrthoDB" id="1365312at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764492" evidence="1">
        <location>
            <begin position="39"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="35"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="317" mass="36063" checksum="1987939230BD8E36" modified="2008-04-29" version="1" precursor="true">MSSQLLPQFKAPILAQPFSAIVKASVAVCMLSSSVTYASEQIMFDDFNYINLAQAEENGWMARTETGHPGIKGATWWSEGVSFHPDPLNYSNQVMRISSKTDGTPANTRQTQVCHKRKYHEGTYAARVYFNDKPQYGPDGDGIVETFYAISPLASPLDPAYSEMDFEYLANGGWGEGDHALFATSWETFQLKPWTPVNAYDATRNSLQGWNTLVLQVSDNKLRYFINGELFAEHGSEVYPEVAMSINFNLWFIPEQTVQHPEMRQYFQDIDWVYFSKDTVLNTQQVTKKVAVLRENKVAQRDTVPDWSPKHEDYCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI65</accession>
    <name>B1KI65_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1251</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323889.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1251"/>
    <dbReference type="EnsemblBacteria" id="ACA85543">
        <property type="protein sequence ID" value="ACA85543"/>
        <property type="gene ID" value="Swoo_1251"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1251"/>
    <dbReference type="eggNOG" id="COG4536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_1_6"/>
    <dbReference type="OMA" id="TIGRQHP"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="2"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="273"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="424" mass="47135" checksum="8C4F5B8DD2AB0A0F" modified="2008-04-29" version="1" precursor="true">MDAISTSILLVILFVLLIISAYFSGSETAMMSLNRYRLKHLASSGNKGAQRAAKMLERPDRLIGLILIGNNLVNILASAIATIIGIRLFGDVGVAIATGVLTLVVLVFSEVTPKTIAALHPERVAFPSSFILKWLLVFLSPLVKTVNFITSGVLHLFGIHSVKSSDALSQEELRTVVHEAGALIPTRHQEMLLSIMDLEKVTVDDIMIPRSDLFAININDDFKSITKQVIQSPHTRVLLYRDNIDDAVGFVHLRDALRLQSKNQFSKSSLLRAVKELYFIPEATPLSVQLSNFQRNKERIGLVVDEYGDIQGLVTLEDILEEIVGDFTTSPEPTPSEEINKQQDGSFLVEATINIRELNKEMAWEFPTDGPKTINGLIVEYFEEIPAPNTSMRIAGYPIEIVEVGENRVNVVRVMPQHFQTPHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI78</accession>
    <name>B1KI78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sigma 54 modulation protein/ribosomal protein S30EA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323902.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1264"/>
    <dbReference type="EnsemblBacteria" id="ACA85556">
        <property type="protein sequence ID" value="ACA85556"/>
        <property type="gene ID" value="Swoo_1264"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1264"/>
    <dbReference type="eggNOG" id="COG1544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071472_3_0_6"/>
    <dbReference type="OMA" id="DMYVAIN"/>
    <dbReference type="OrthoDB" id="2088581at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="13936" checksum="38AE792A5FF81DEA" modified="2008-04-29" version="1">MTKITSKNLEVTPLIRERIQARLDKLARHDIQLINPHVIIVQEKQLFKIEAAVGIPSHKLFAQAKHEDLYSAINAMGQKLEKQLNRLTHKPEAQRYETLKRQEETVDLNIEDEIDEEFAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIC5</accession>
    <name>CLPS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name type="ordered locus">Swoo_2700</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325314.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KIC5"/>
    <dbReference type="SMR" id="B1KIC5"/>
    <dbReference type="STRING" id="392500.Swoo_2700"/>
    <dbReference type="EnsemblBacteria" id="ACA86976">
        <property type="protein sequence ID" value="ACA86976"/>
        <property type="gene ID" value="Swoo_2700"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2700"/>
    <dbReference type="eggNOG" id="COG2127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134358_2_1_6"/>
    <dbReference type="OMA" id="NDDYTSM"/>
    <dbReference type="OrthoDB" id="1829294at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000115477" description="ATP-dependent Clp protease adapter protein ClpS">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <sequence length="102" mass="11548" checksum="4AB682E20B594C5A" modified="2008-04-29" version="1">MGKAGNIEHVEERVESEVMPPSMYKVILNNDDYTPMDFVIEVLQLFFKKTEEQATDIMLAIHHQGKGICGIFPFGIAETKVAQVNQFARQNQHPLLCSLEKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KID0</accession>
    <name>MNMA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="1">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mnmA</name>
        <name type="ordered locus">Swoo_2705</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325318.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KID0"/>
    <dbReference type="SMR" id="B1KID0"/>
    <dbReference type="STRING" id="392500.Swoo_2705"/>
    <dbReference type="EnsemblBacteria" id="ACA86981">
        <property type="protein sequence ID" value="ACA86981"/>
        <property type="gene ID" value="Swoo_2705"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2705"/>
    <dbReference type="eggNOG" id="COG0482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035188_1_0_6"/>
    <dbReference type="OMA" id="AVCTGHY"/>
    <dbReference type="OrthoDB" id="1054741at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000349794" description="tRNA-specific 2-thiouridylase MnmA">
        <location>
            <begin position="1"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with target base in tRNA" evidence="1">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="1">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="1">
        <location>
            <begin position="322"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="1">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="22"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="1">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Alternate" evidence="1">
        <location>
            <begin position="113"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <sequence length="377" mass="41990" checksum="3716C42D57F4BCD1" modified="2008-04-29" version="1">MAIIEPTAALIEPTANKKVIVGMSGGVDSSVSAYLLLKQGYQVEGLFMKNWEEDDTDEYCAAADDLKDAQAVCDKLGIKLHTVNFASEYWDNVFEYFLAEYKAGRTPNPDIICNKEIKFKAFLEFADDILDADYIAMGHYVRRSDDSGQSQMLRGIDGNKDQSYFLYTLSHEQVSRSLFPVGELEKSEVREIAKEMGLITHDKKDSTGICFIGERKFTDFLSTFLPAQPGNIETAEGEVIGTHQGLMYHTLGQRKGLGIGGMKNSNDDPWYVVDKEMDRNVLVVGQGGNHPRLMSTGFYADQLHWVDRIGPDNGAKITVKTRYRQRDVACSLHYDGEDRVKVLFDEPVAAVTPGQSAVFYDAEVCLGGGIIDSLIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIJ1</accession>
    <name>B1KIJ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mammalian cell entry related domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326814.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4231"/>
    <dbReference type="EnsemblBacteria" id="ACA88487">
        <property type="protein sequence ID" value="ACA88487"/>
        <property type="gene ID" value="Swoo_4231"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4231"/>
    <dbReference type="eggNOG" id="COG1463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107027_0_0_6"/>
    <dbReference type="OMA" id="QYQFPKD"/>
    <dbReference type="OrthoDB" id="807474at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030970">
        <property type="entry name" value="ABC_MlaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04430">
        <property type="entry name" value="OM_asym_MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="39"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="155" mass="16747" checksum="3E308DCCF637A6C7" modified="2008-04-29" version="1" precursor="true">MLTRKIEILVGLFILSGLAAFLVLVFNVANVEVKANGSNYTLYAKFSNIGGLKVRSPVKVGGVVVGRVSEINLDPTELVPVVKLSMDKRFNQFPETSSLSILTSGLLGEQFLGLTPGFIDDDIAMLVDGDRIDDTHSALVLEELIGQFLYSASKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIQ5</accession>
    <name>B1KIQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326878.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88551">
        <property type="protein sequence ID" value="ACA88551"/>
        <property type="gene ID" value="Swoo_4296"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4296"/>
    <dbReference type="HOGENOM" id="CLU_1593423_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="167" mass="18709" checksum="591630A9FCE1FB50" modified="2008-04-29" version="1" precursor="true">MKLALSQIILVSLLILVGCGGGSSDSSVNACSDGTQIPKHLVGTWAREFNRGGQKIFYEFTSGCQLIYYQIADKGFVERDMDITLAESGYYRIYHEPFMVISSVNETDSVMYLDNWVGQVIVQNESTKEIVFKQDKSMDISHLSYEVDDSGQSLKLGTSDNAFYREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIS5</accession>
    <name>B1KIS5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">OmpA/MotB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_1281</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323919.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1281"/>
    <dbReference type="EnsemblBacteria" id="ACA85573">
        <property type="protein sequence ID" value="ACA85573"/>
        <property type="gene ID" value="Swoo_1281"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1281"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031536_2_0_6"/>
    <dbReference type="OMA" id="YAWDVFG"/>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000498">
        <property type="entry name" value="OmpA-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01389">
        <property type="entry name" value="OmpA_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766668" evidence="12">
        <location>
            <begin position="22"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="13">
        <location>
            <begin position="243"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA85573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="367" mass="40440" checksum="56A42A9378C1686F" modified="2008-04-29" version="1" precursor="true">MMNNTLKAVLLTSMLPFAANAAQELTPWYVGGGVGVNDYEPSCDLKTMKVCGKDDPYAWDVFGGYLFNDYFGVELGYRDLGRGEWTDYANKRNDVGAKGMTLGLVGFMPLSQRWSLSAEAGAMNYLLSNNKQYGTEYYSDSGVAPYFGVGVGYNITENLKLQAKYRRYENLEDDKWNTLDMESNYWGLELSYRFGRTAPAAVVAPVVAAPVDSDNDGVTDDMDQCPNTPSTHQVDGNGCTIYKETTEQRDVGSIQFANNSSVVKNESYQQIEKLANYMNQHPKSTVLISGHASDVGKAEYNMMLSDKRANAVAKILVEKYGIAQDRVEAKGFGITQPIIEGSSPAANKANRRIEAHVTGVKKEALIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIU0</accession>
    <name>B1KIU0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly protein PilW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1296"/>
    <dbReference type="EnsemblBacteria" id="ACA85588">
        <property type="protein sequence ID" value="ACA85588"/>
        <property type="gene ID" value="Swoo_1296"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1296"/>
    <dbReference type="eggNOG" id="COG4966">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052493_0_0_6"/>
    <dbReference type="OMA" id="GDMTGTD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032092">
        <property type="entry name" value="PilW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16074">
        <property type="entry name" value="PilW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="326" mass="35714" checksum="3AE6956926012E4B" modified="2008-04-29" version="1" precursor="true">MRQLMRNKGIQVSGFSLVELMVAMVIGLFLSAGLFSMFNMSATNVTTTSQFNQLQENGRIALALVERDISQLGFMGDMTGTDFVLGANTQIPAGGVPNDCVGAGANNASLPNNTPSHFRRLWGYESGVSGDSLACLNSVNSGTDVLQIKRLIGPATTTPNLNTRYYVAATPNQAIFFVGNPAPPVLANARFWEYQHHVYYIANDGDIPVLRRRTLSVNNGMANEDQLVEGIENIRVLYGFDNDGDNTADSFMPVQNVTNLMWDNELFQRLVALRIFVLVRAVEADNSYTNNTDYVLGDKTVAATGDNFRRKVVSTTVVLENPVLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ28</accession>
    <name>B1KJ28_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
            <ecNumber evidence="3">2.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.79" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325384.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2772"/>
    <dbReference type="EnsemblBacteria" id="ACA87048">
        <property type="protein sequence ID" value="ACA87048"/>
        <property type="gene ID" value="Swoo_2772"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2772"/>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026434_0_2_6"/>
    <dbReference type="OMA" id="LDPTMMY"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008825">
        <property type="term" value="F:cyclopropane-fatty-acyl-phospholipid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR003085-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="420" mass="48178" checksum="7CFD79DCDD842ADE" modified="2008-04-29" version="1">MESTQKQISLVKSSWLIDRYRLLLHKVLSRLQGGYVEIDEAGCTLGFGDIHSELKSKIVVLDSEFYRALIQNGSIGGAESYIAQQWTCSNLTTLIQIMARNQSQLDELDSKTQWLSKLKNQFLRFQNANTEKGSKQNILAHYDIGNDLYKHFLDPEMLYSCAIYSDKAQDLDSAQLNKMDEICQKLELNPSDHLIEIGTGWGGLAIHAATHYGCKVTTTTISDEQYLYAKRRIEVLGLSEQITLLKSDYRKLEGQYSKLVSIEMIEAVGHEYLKGFFSICSGLLKPDGKMLIQAITIADQRYDKYRCSVDFIQKYIFPGGCLPSVNIMAHHIASDTDMVIDAMDDIGVHYARTLNDWRERFEQEWHYLASTGYDEEFKRLWLFYFAYCEGAFLERVISTHHVVARKPEHIGYKNETILAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ41</accession>
    <name>B1KJ41_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoid-associated protein Swoo_2785</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_2785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Cytoplasm</location>
            <location evidence="1 3">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the YejK family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325397.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2785"/>
    <dbReference type="EnsemblBacteria" id="ACA87061">
        <property type="protein sequence ID" value="ACA87061"/>
        <property type="gene ID" value="Swoo_2785"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2785"/>
    <dbReference type="eggNOG" id="COG3081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063050_0_1_6"/>
    <dbReference type="OMA" id="FFMDFLA"/>
    <dbReference type="OrthoDB" id="1368516at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00730">
        <property type="entry name" value="NdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007358">
        <property type="entry name" value="Nucleoid_associated_NdpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38772">
        <property type="entry name" value="PTHR38772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04245">
        <property type="entry name" value="NA37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="343" mass="38368" checksum="CA1BC3640F4FB655" modified="2008-04-29" version="1">MSINVEQAIIHAISQDREGQLSCRLRPQPLLNSEAVEAMLEELHQTYTTKAGKGFGHFGTHGEDGEANPKFEQALSEYRNGELGFVEFSGLAGKLLQEELSKYDFSQGGFLLLSCYTHMTSDYLYVSLLNAKSSMTVLDDMELSQNTHLDLKDVQLAARIDLTEWQADSDSRKYISFIRGRAGRKVADFFLDFMGCVEGVNTKAQNKQLMNAVEDFVSSSELTKDERQQCREKVFDYCTERCEVGADIEIKDLADELADSGMESFYDFARGGEYELEDEFPGDKPTLRQLKKFSGTGGGVTLSFDGAHLGERVMYDPISDTIMIKGVPANLKDQLDRRLKGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJB8</accession>
    <name>B1KJB8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88590">
        <property type="protein sequence ID" value="ACA88590"/>
        <property type="gene ID" value="Swoo_4337"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4337"/>
    <dbReference type="eggNOG" id="ENOG5030PAK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165523_0_0_6"/>
    <dbReference type="OMA" id="QIQCPHC"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="130" mass="14621" checksum="BF574196CA070AAD" modified="2008-04-29" version="1">MNILLNFTLIPQVPKESQAVLCAHCSQFFGVNAVKNQRGKGFGAQLQCPHCDAWLGKSPLLSRFKMLGFYLAVVALGYGYFTPEMRNLTTPIAILAVMVLLVSHMMDHLKVVEAPEKLDIDDSEHRQKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJG1</accession>
    <name>B1KJG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction histidine kinase, LytS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326959.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4381"/>
    <dbReference type="EnsemblBacteria" id="ACA88633">
        <property type="protein sequence ID" value="ACA88633"/>
        <property type="gene ID" value="Swoo_4381"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4381"/>
    <dbReference type="eggNOG" id="COG2972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020473_1_1_6"/>
    <dbReference type="OMA" id="PNLLFYI"/>
    <dbReference type="OrthoDB" id="1031920at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="176"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="377" mass="43139" checksum="595A12D22A13DD2C" modified="2008-04-29" version="1">MMIGKLNTSSLMSNKNAQLWLLVLGYWCFVSVISLFTLTLWYGAISWLHIGHTIIQSALGFILSFPLYFAVMAIWEQSLFMRVLKSILLTIFVALIWTVARLAIFIHMTTFDDQWNDFGGWLFGSIFIYLGLVGFFHGMKYFQLLQNKHDVMLKTEAEIKEEQIKTMRAQTVARDAQIKMLRYQLNPHFLCNTLNAINSLIEIEEPKKAQRMAIQLSKFLRYSLDNNPNTKITLENELNALNLYLEIEKTRFSERLKLDFNIDKQALQASIPSLLLQPIIENSMKHVIAKNENGGTIRLSANITDHQLVLVLSDTGSTNIDSKMLKSSKGRGIGLRNIDERLKILYGNDFLFELNIMASGALKTTIKIPYEPLNNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJH3</accession>
    <name>B1KJH3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secretion protein HlyD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326971.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4393"/>
    <dbReference type="EnsemblBacteria" id="ACA88645">
        <property type="protein sequence ID" value="ACA88645"/>
        <property type="gene ID" value="Swoo_4393"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4393"/>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_6_1_6"/>
    <dbReference type="OMA" id="DAWAVFQ"/>
    <dbReference type="OrthoDB" id="1680841at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="1">
        <location>
            <begin position="39"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="323" mass="35692" checksum="AF830BB95E6D7C91" modified="2008-04-29" version="1" precursor="true">MRANRLLAIIALILLVLLLGYGLKLAYSPKPQILQGQIEAREYNVSSKVPGRVEQVLVRRGDLVEKGDLLFAIHSPELDAKLMQAEGGRDAAKALQQEADSGARKQQVMASKEQWLKAKAAATLGKTTYERVENLFVEGVVARQKRDEAFTQWQAAKYTEQAALAMYQMAEEGARVETKAAAAGNARMAEGAVNEVSAILEDSQMRSPKSGEVSEVLLQAGELAPSGFPVVSLIDMKDAWAVFQVREDQLKQFSKGSKMMLTLPALDRDVEFTVTHVSVMGEFATWRSTESGHDFDMRTFEVELRTDTEIPDLRVGMSVIFTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJJ4</accession>
    <name>B1KJJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324013.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1375"/>
    <dbReference type="EnsemblBacteria" id="ACA85667">
        <property type="protein sequence ID" value="ACA85667"/>
        <property type="gene ID" value="Swoo_1375"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1375"/>
    <dbReference type="eggNOG" id="COG1237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036012_0_0_6"/>
    <dbReference type="OMA" id="CSGWRAK"/>
    <dbReference type="OrthoDB" id="1815576at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07713">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041712">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767404" evidence="1">
        <location>
            <begin position="24"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="51"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="317" mass="34315" checksum="B2277BCD03547562" modified="2008-04-29" version="1" precursor="true">MSKSLYLLLMLVSIVSPISGVNAKEFTQASTLKVTTLSTMLASRGIGEWGYSALIEVDGKKILFDTGNRPETVLQNAQTLGIDLSDVEDVILSHNHGDHTGGLLTLRKTLRVQNPKALSRIHVGKGIFAERANSRNSILTMRDQLIKLGSEFIVYEKPTEIFPGVWLTGQVPRVHPEKNWSGKGQIVTQAGLVEDNIPEDLSLVIDTNQGFVLISGCGHAGIINTMEHITANIHPSKIAAAIGGFHLVSATDEHLAWTAKKLQDFGVDQMIGAHCTGIDALYTLRGHLASDRKHMVVGSIGDQFTLKTGIKAGFIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJJ5</accession>
    <name>B1KJJ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324014.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85668">
        <property type="protein sequence ID" value="ACA85668"/>
        <property type="gene ID" value="Swoo_1376"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1376"/>
    <dbReference type="HOGENOM" id="CLU_1509591_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="20362" checksum="1F3788BE0482DEC5" modified="2008-04-29" version="1">MREIYTVDQLEDWFAEWSFKQGRIYCPIDELLIPMVRHLRNSHLLKGCSSEDGETLDDLFRLMIEPTTPTVNCRLKTEPTTEQVKQFCDVVFKHLGKTQLTVAVTLILVKHVGLPTPSYRLIPDAPVIKKTEVIDLSPVMTICGRLGIFETCPICGKGKARLDWLTGYYNECQECEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJL4</accession>
    <name>B1KJL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324033.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1395"/>
    <dbReference type="EnsemblBacteria" id="ACA85687">
        <property type="protein sequence ID" value="ACA85687"/>
        <property type="gene ID" value="Swoo_1395"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1395"/>
    <dbReference type="eggNOG" id="COG3797">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106303_2_0_6"/>
    <dbReference type="OMA" id="GDGVIYW"/>
    <dbReference type="OrthoDB" id="1382593at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012545">
        <property type="entry name" value="DUF1697"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36439">
        <property type="entry name" value="PTHR36439"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08002">
        <property type="entry name" value="DUF1697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008502">
        <property type="entry name" value="UCP008502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="171" mass="19332" checksum="327158F9127D48FF" modified="2008-04-29" version="1">MNRYTILLRGVNVGGKNLLPMKELKALLENNGFNNVTTYIQSGNLLLTGHEHPEKKICELIQTHFGFTPETLVLTKDEFKLAISNCPFQKGENKFIHFYFCKDSPKADTTKILALASQTERFELLDKIFYLHAPDGIGRSKLVANIESCLGVRATGRNLNTINKLNEMMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJM5</accession>
    <name>B1KJM5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-oxalocrotonate decarboxylase</fullName>
            <ecNumber evidence="2">4.1.1.77</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324044.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1406"/>
    <dbReference type="EnsemblBacteria" id="ACA85698">
        <property type="protein sequence ID" value="ACA85698"/>
        <property type="gene ID" value="Swoo_1406"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1406"/>
    <dbReference type="eggNOG" id="COG3971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060136_4_0_6"/>
    <dbReference type="OMA" id="YVHPRVE"/>
    <dbReference type="OrthoDB" id="1314120at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047437">
        <property type="term" value="F:4-oxalocrotonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="83"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="261" mass="27957" checksum="AC8850A75BF18A0F" modified="2008-04-29" version="1">MLIDLAKKLDQAAADAASIAQLSSTTQLSLDDAYKVQKISIEQRLIRGEKLVGYKMGFTSKAKMIQMGVDDLIWGRLTDAMMIQDGGSIDLSKYVHPRAEPEIAFRLKKPLAGIVTKEEAYDAIDAVAGAIEVIDSRYQNFKFSLSDVIADNCSSTGFVVGPWHSPDTNIDGLSMILKVNDAEVERGSSKDILDHPLNSLIEAARCVAQYGESLQAGQIILAGAATAAVALKPGQTISTEIEGLSPCQFSTSNNSSSQASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJP5</accession>
    <name>B1KJP5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_1426</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324064.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1426"/>
    <dbReference type="EnsemblBacteria" id="ACA85718">
        <property type="protein sequence ID" value="ACA85718"/>
        <property type="gene ID" value="Swoo_1426"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1426"/>
    <dbReference type="eggNOG" id="COG4206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010745_0_0_6"/>
    <dbReference type="OMA" id="QPEFDRT"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764576" evidence="5">
        <location>
            <begin position="30"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="55"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="416"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="969" mass="104804" checksum="4EE95518C894F8A6" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ5</accession>
    <name>B1KJQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-phosphoglucomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1436</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324074.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1436"/>
    <dbReference type="EnsemblBacteria" id="ACA85728">
        <property type="protein sequence ID" value="ACA85728"/>
        <property type="gene ID" value="Swoo_1436"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1436"/>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_13_3_6"/>
    <dbReference type="OMA" id="LMRSISF"/>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008801">
        <property type="term" value="F:beta-phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02598">
        <property type="entry name" value="HAD_BPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010976">
        <property type="entry name" value="B-phosphoglucomutase_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010972">
        <property type="entry name" value="Beta-phosphoglucomutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01990">
        <property type="entry name" value="bPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02009">
        <property type="entry name" value="PGMB-YQAB-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="114"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups" evidence="4">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups" evidence="4">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="233" mass="25006" checksum="AD7B1D11B3A68564" modified="2008-04-29" version="1">MALQAAIFDLDGVLTDTAEFHFIAWQSIAQSLGVDFSLDDNEKLKGVDRHNSLQHILNKGNLTIDEQAFNQLLDRKNKHYLSLIASITPQHLFEGVLACFTSLKARGIKIGLASASKNATLVLNKLGIESLFDFVGDAASVKNSKPAPDIFLSVAAGLGVDAHDCMGIEDAAAGVTAIKSAKMYAVGIGDKNTLCQADQIFTTFNQLNLHLSDCLTAFESSQHSKVESPQVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT4</accession>
    <name>B1KJT4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1842 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325457.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2846"/>
    <dbReference type="EnsemblBacteria" id="ACA87121">
        <property type="protein sequence ID" value="ACA87121"/>
        <property type="gene ID" value="Swoo_2846"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2846"/>
    <dbReference type="eggNOG" id="ENOG503355S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1617902_0_0_6"/>
    <dbReference type="OMA" id="VEHAVMT"/>
    <dbReference type="OrthoDB" id="1344267at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014992">
        <property type="entry name" value="DUF1842"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08896">
        <property type="entry name" value="DUF1842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1842" evidence="1">
        <location>
            <begin position="7"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="164" mass="17992" checksum="27BCF56C156F42AA" modified="2008-04-29" version="1">MSKENQVGLFRVSYVISPSVAGHPLLGATQLRLELVVNTVDKTVNGVGHVFQSTNPPVNVISQFSGEWSYMCTMNSCNILVVADGFDFSSILIGGHPVEHKNATLRMSLGEDWQSGVANFSYLYEGEWYEIEAAQVVVSNDETQQNLDALTTFTTANKPKVSMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKB5</accession>
    <name>B1KKB5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324101.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1467"/>
    <dbReference type="EnsemblBacteria" id="ACA85755">
        <property type="protein sequence ID" value="ACA85755"/>
        <property type="gene ID" value="Swoo_1467"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1467"/>
    <dbReference type="eggNOG" id="ENOG5031MJA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168743_0_0_6"/>
    <dbReference type="OMA" id="YWMIKDE"/>
    <dbReference type="OrthoDB" id="2018584at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767430" evidence="1">
        <location>
            <begin position="22"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12594" checksum="765460EA2708B393" modified="2008-04-29" version="1" precursor="true">MKNIRRILFILMASIAMPVFAGSQTGLVTNINVRDDGLHWFTLSGDRGVMPACTRERFTYWMIKDENSTYGKSQFSMLLAAYMAQKTVTIIGTDSCTRWGDGEDIKVVQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG0</accession>
    <name>B1KKG0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">Swoo_1512</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324146.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1512"/>
    <dbReference type="EnsemblBacteria" id="ACA85800">
        <property type="protein sequence ID" value="ACA85800"/>
        <property type="gene ID" value="Swoo_1512"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1512"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004377_0_0_6"/>
    <dbReference type="OMA" id="FLDMQMA"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032006">
        <property type="term" value="P:regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015019">
        <property type="entry name" value="LAMTOR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01278">
        <property type="entry name" value="MAPKK1_Int"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="17">
        <location>
            <begin position="370"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="15">
        <location>
            <begin position="451"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="16">
        <location>
            <begin position="509"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="704"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="941"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="1101"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="18">
        <location>
            <begin position="1291"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1228"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1228"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="997"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="1153"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="9">
        <location>
            <position position="1330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACA85800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1480" mass="165420" checksum="D001A30D8A589B53" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKG7</accession>
    <name>B1KKG7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85807">
        <property type="protein sequence ID" value="ACA85807"/>
        <property type="gene ID" value="Swoo_1519"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1519"/>
    <dbReference type="HOGENOM" id="CLU_122898_0_0_6"/>
    <dbReference type="OMA" id="YHVEDIY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="194" mass="21588" checksum="40F6ECCB1668F514" modified="2008-04-29" version="1">MMTEIEYELDGKSIETLQMLVGLEVNLITQSASLHLSQGCGSSLSPLYFRGSPGFIEMSNEWHTSPDGHDFHLPKFRLLQKPGEIEYSEHNNSVGPCSEIKMSENNSAVIETIEVLSLSCRFAVGDKASNLTLSDEILTYDWGINIRLSDGSSVSITTEDDSILGEFIISPKAMEPYRKEGISIEQLDIRLRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKM7</accession>
    <name>B1KKM7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325580.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87244">
        <property type="protein sequence ID" value="ACA87244"/>
        <property type="gene ID" value="Swoo_2973"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2973"/>
    <dbReference type="eggNOG" id="ENOG50318TV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2156638_0_0_6"/>
    <dbReference type="OMA" id="MICTTFY"/>
    <dbReference type="OrthoDB" id="1945076at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767160" evidence="1">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="111" mass="12190" checksum="6C8EA17C86AFDE51" modified="2008-04-29" version="1" precursor="true">MKKIFLAGLVSCVFAGSAMAETLETDDAIGMASLMMCSTFYSENEMVVEGTIVNRSMSAHREAGIDEMIMTPETSANLDLYVAQFQAADKEQSMKLCDAALKYARESHFIK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKW9</accession>
    <name>SECA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="1">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">secA</name>
        <name type="ordered locus">Swoo_4525</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + cellular proteinSide 1 = ADP + phosphate + cellular proteinSide 2.</text>
            <dbReference type="EC" id="7.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">May bind 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327101.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KKW9"/>
    <dbReference type="SMR" id="B1KKW9"/>
    <dbReference type="STRING" id="392500.Swoo_4525"/>
    <dbReference type="EnsemblBacteria" id="ACA88775">
        <property type="protein sequence ID" value="ACA88775"/>
        <property type="gene ID" value="Swoo_4525"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4525"/>
    <dbReference type="eggNOG" id="COG0653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005314_3_0_6"/>
    <dbReference type="OMA" id="MVHYDVQ"/>
    <dbReference type="OrthoDB" id="212453at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008564">
        <property type="term" value="F:protein-exporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0811">Translocation</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000145062" description="Protein translocase subunit SecA">
        <location>
            <begin position="1"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="873"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="105"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="891"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="893"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="902"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="903"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="907" mass="102726" checksum="3641C5FF48E01AFA" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKZ0</accession>
    <name>B1KKZ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane protein involved in aromatic hydrocarbon degradation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_4546</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327122.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4546"/>
    <dbReference type="EnsemblBacteria" id="ACA88796">
        <property type="protein sequence ID" value="ACA88796"/>
        <property type="gene ID" value="Swoo_4546"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4546"/>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035981_0_0_6"/>
    <dbReference type="OMA" id="KQENWED"/>
    <dbReference type="OrthoDB" id="620166at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765013" evidence="8">
        <location>
            <begin position="24"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="432" mass="46599" checksum="64D28AA72EBEB07F" modified="2008-04-29" version="1" precursor="true">MNKRILSVAVIAAIMGTTTQVQAAGFQLAEYSATGLGRAYAGEAAMADNAAAQFRNPAMLTYLQGTQMTTGAILVMPNIDVDGEVTYVDGKNPTSAKDIAGDAVVPNFYVSHQLNEQWFLGVALGSNFGMATELDDSFRGNQFGNEASVTTVELNPNIAYRINDQFSIGAGVRFVMGEGSFGAKSSVDVPLSASLIIPKGTTLKYMEGDDTSWGWQLGGAWQINANNRIGFNYRSEVEQNLEGEANGLGFSMLEGSMNASKIYAGAMELTLPATAEIASFHQLTDKLAVHASVNWTDWSSFEKLEAKIPELSNSAILVKEENWKDNYRFALGATYELSAKSSLRAGVAYDQAAVDDIHRTATIPEVNRLWLSAGYGYQYSENLAFDFGATYIFADESPMHEADTDSLPFGGAFEGQVSGNIMLVGVQASYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL11</accession>
    <name>B1KL11_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ordered locus">Swoo_4567</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327142.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4567"/>
    <dbReference type="EnsemblBacteria" id="ACA88817">
        <property type="protein sequence ID" value="ACA88817"/>
        <property type="gene ID" value="Swoo_4567"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4567"/>
    <dbReference type="eggNOG" id="COG0461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074878_0_1_6"/>
    <dbReference type="OMA" id="MKAYQRQ"/>
    <dbReference type="OrthoDB" id="1280396at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="45"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Orotate binding" evidence="4">
        <location>
            <begin position="34"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="124"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA88817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="213" mass="23539" checksum="296045005FA2F163" modified="2008-04-29" version="1">MKAYQREFIEFALERQVLRFGEFTLKSGRTSPYFFNAGLFNTGRDLARLGRFYAAALVDSGIEHDLLFGPAYKGIPIATTTAVALCEHHDIDIPYCFNRKEKKDHGEGGSLVGSELKGRVMLVDDVITAGTAIRESMEIIAAHEAKLAGVLIALDRQEKGKGELSAIQEVERDFGCDIVSIIKLGDLINYLSEKPGMEAQLESVSAYRDQYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL61</accession>
    <name>B1KL61_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paraquat-inducible protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322751.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0101"/>
    <dbReference type="EnsemblBacteria" id="ACA84402">
        <property type="protein sequence ID" value="ACA84402"/>
        <property type="gene ID" value="Swoo_0101"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0101"/>
    <dbReference type="eggNOG" id="COG2995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115847_0_0_6"/>
    <dbReference type="OMA" id="RGMLNMV"/>
    <dbReference type="OrthoDB" id="836803at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007498">
        <property type="entry name" value="PqiA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04403">
        <property type="entry name" value="PqiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="219" mass="23598" checksum="0C379BFF66990E44" modified="2008-04-29" version="1" precursor="true">MSKNRIFTTAILLISLALLIPGVTQPILSISGSIEKSELTKAGIDQLATSLGDNSASGNTRGMLSMFSGMLGLNDLEGEVEVFQKTRSIWGTVDELFRSGNAAVAALVMLFSVIIPVLKLSLMLLQQLPITPSFRQAITGFTTKISKWSMADVFVVALIVTYMAGNASAGMGEMLKTTANFEVGFYYFSAYCLFSIASTYLVNTDVTESDTSLPETERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL83</accession>
    <name>B1KL83_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322773.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84424">
        <property type="protein sequence ID" value="ACA84424"/>
        <property type="gene ID" value="Swoo_0123"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0123"/>
    <dbReference type="eggNOG" id="ENOG5032UCI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094218_0_0_6"/>
    <dbReference type="OMA" id="CQDNELF"/>
    <dbReference type="OrthoDB" id="1318694at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766782" evidence="1">
        <location>
            <begin position="23"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="258" mass="28846" checksum="A40894705DA1E408" modified="2008-04-29" version="1" precursor="true">MKNTLTLTLLTCLISMAAPAAADTNSAIDDSHSTNKFTPNQDNETQYLIDLGWDSDYISEGRNNLDKGGIFWSSAAVQHGNLNVYATMGRADSQHYTEWNLGLEYSIALTENLETTLGYQRIESYGDERCSDNELFGSLSYSGVEWLTPSINYTYATEASGYFVEASLHSSWELLDGFTFTPYVTQAFDFQYATEDHNGPNHFQFGVEAEYQLAQNVIISGHVSHTIAQEDIKLEAKMDEVESSLDQTFAGVHLTWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLA3</accession>
    <name>B1KLA3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase J</fullName>
            <ecNumber evidence="1">2.1.1.266</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (adenine(2030)-N6)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m6A2030 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmJ</name>
        <name evidence="2" type="ordered locus">Swoo_0143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the adenine in position 2030 of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43736"/>
            <dbReference type="Rhea" id="RHEA-COMP:10668"/>
            <dbReference type="Rhea" id="RHEA-COMP:10669"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.266"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RlmJ family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.266" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322793.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0143"/>
    <dbReference type="EnsemblBacteria" id="ACA84444">
        <property type="protein sequence ID" value="ACA84444"/>
        <property type="gene ID" value="Swoo_0143"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0143"/>
    <dbReference type="eggNOG" id="COG2961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061769_0_0_6"/>
    <dbReference type="OMA" id="TYAIWYP"/>
    <dbReference type="OrthoDB" id="1186316at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036307">
        <property type="term" value="F:23S rRNA (adenine(2030)-N(6))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00934">
        <property type="entry name" value="23SrRNA_methyltr_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007473">
        <property type="entry name" value="RlmJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37426">
        <property type="entry name" value="PTHR37426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04378">
        <property type="entry name" value="RsmJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="144"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate rRNA" evidence="1">
        <location>
            <position position="4"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="280" mass="31428" checksum="CD1A22683FDAFE7F" modified="2008-04-29" version="1">MLSYRHGYHAGNYADVLKHSVLLQVLKLMHKKPTPFAYIDTHAGAGGYALTDQFSQKTGEYLEGVAKLWGKEDLPEPLAEYIADVAHFNQGKSELSFYPGSPAFVDMNRHEKERMVLHELHGADHALLEEQFTGDRYIRVVKDDGLKGLIAAVPPRERRGVILVDPSYEIKTDYQDVPNAIIKAHKKFATGVYMLWYPVVNRAQTEGMLKILAQSGIKNQLRIEQAIRADSDEFGMTAAGLWIINPPWQLDTKASEILEYLSPVLNQGGGKITIKQEVPE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-11-25" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLC4</accession>
    <name>MLTF_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Membrane-bound lytic murein transglycosylase F</fullName>
            <ecNumber evidence="1">4.2.2.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Murein lyase F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mltF</name>
        <name type="ordered locus">Swoo_1563</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exolytic cleavage of the (1-&gt;4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.</text>
            <dbReference type="EC" id="4.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Cell outer membrane</location>
            <topology>Peripheral membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Attached to the inner leaflet of the outer membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transglycosylase Slt family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324195.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KLC4"/>
    <dbReference type="SMR" id="B1KLC4"/>
    <dbReference type="STRING" id="392500.Swoo_1563"/>
    <dbReference type="CAZy" id="GH23">
        <property type="family name" value="Glycoside Hydrolase Family 23"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85849">
        <property type="protein sequence ID" value="ACA85849"/>
        <property type="gene ID" value="Swoo_1563"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1563"/>
    <dbReference type="eggNOG" id="COG4623">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027494_0_1_6"/>
    <dbReference type="OMA" id="YYDILTW"/>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016837">
        <property type="term" value="F:carbon-oxygen lyase activity, acting on polysaccharides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02016">
        <property type="entry name" value="MltF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023703">
        <property type="entry name" value="MltF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0998">Cell outer membrane</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5000317081" description="Membrane-bound lytic murein transglycosylase F">
        <location>
            <begin position="16"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Non-LT domain" evidence="1">
        <location>
            <begin position="16"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="LT domain" evidence="1">
        <location>
            <begin position="260"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02016"/>
        </source>
    </evidence>
    <sequence length="480" mass="54833" checksum="D2CBD24F7F47E227" modified="2008-04-29" version="1" precursor="true">MNRILLTLLTLTLLAGCQRVAVEETKLVPPAVEKTVLNVGTIYGSQIYVTTGQGEAGFDYEMASRFADHLELELAMKPYSNIKELYQALNSGEVDLIAAGLADTPTRRENFRLGPPLYRVNQVLVYKQGTPQPKDISQLKDEITVITDSSFVDTLSQLQKIYPELVWDQEQDKDNEELLAMIARGEISYTIADSTTFEISRRYMPELRAGLTLKEKQAIVWLLPAQNSDKLMSELLTFWHGEKLDGTLAHLDEKYFAHVKRFDYVDTRAFLRAIDNKLPKYKERFQYYAGDLDWRKLAATAYQESHWNPNARSPTGVRGLMMLTLPTAKQMGIENRLDAEQSIKGGAKYLRGILNRLPDSIPDNQRMWFALASYNIGYGHVEDARKLAESMGLNPSAWRDLKEVLPLLQKRKYYKQTRYGYARGNEAVHYVDNIRRYYDTLVWIDNQNKLLEENQALIEESQLADQIGIGEKAITGAQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLU7</accession>
    <name>B1KLU7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_4577</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327152.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4577"/>
    <dbReference type="EnsemblBacteria" id="ACA88827">
        <property type="protein sequence ID" value="ACA88827"/>
        <property type="gene ID" value="Swoo_4577"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4577"/>
    <dbReference type="eggNOG" id="COG2135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1178864_0_0_6"/>
    <dbReference type="OMA" id="RTTFNAR"/>
    <dbReference type="OrthoDB" id="1718602at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="230" mass="26390" checksum="B617D2436D1E395B" modified="2008-04-29" version="1">MCGRLNMIDDLFMRALMQDLSVSNPNEMLFDRFKMPTNEISIVREINGIRQLQTATWWLLQDMGYAGFKPSKYTSFNTRYDKLNQFGSAGYAPFRESRCIVIAKGFGETEKRGSTVEYYDFIAQDSAITLGGLFQEWQHPKTGEHKISCSIITNPPHPDMQAFHSKASPLILPQSTSVRDAWLDPNNHQVEMFEHLLTPALRHNFLVQQIEKPSLYKVIGEAQQLHPYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLZ7</accession>
    <name>B1KLZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4627"/>
    <dbReference type="EnsemblBacteria" id="ACA88877">
        <property type="protein sequence ID" value="ACA88877"/>
        <property type="gene ID" value="Swoo_4627"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4627"/>
    <dbReference type="HOGENOM" id="CLU_1991165_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="125" mass="13703" checksum="F8EED59B648B8E89" modified="2008-04-29" version="1">MPKLNIEVPDELIQKGISYLLESPVLFGLTVLCGVSGHLIFFMIFTYFSDQDATKTYLNTMLGKISLGALLYAVVALPIYIVEYGSMSIEYTKLMAIVPSAIIIGLFLQAGFFGVFIYRKGSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM05</accession>
    <name>B1KM05_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327209.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4635"/>
    <dbReference type="EnsemblBacteria" id="ACA88885">
        <property type="protein sequence ID" value="ACA88885"/>
        <property type="gene ID" value="Swoo_4635"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4635"/>
    <dbReference type="eggNOG" id="ENOG5033HZS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152376_1_0_6"/>
    <dbReference type="OMA" id="LPIDGRH"/>
    <dbReference type="OrthoDB" id="2001708at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767197" evidence="1">
        <location>
            <begin position="26"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14245" checksum="36840D907CF0D0CC" modified="2008-04-29" version="1" precursor="true">MKRSNLVKTLLSLTPLLLMGCSLQADDSQQPAPLPALVSAPSPESIAELEAAIASLLKIERVTIADDAFTRSSRLSLERSPHKAPNGQLIMGRNFELPQTVQLWISAEICFVTDADNHRSAPLTHTQCKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KM49</accession>
    <name>B1KM49_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322811.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0161"/>
    <dbReference type="EnsemblBacteria" id="ACA84462">
        <property type="protein sequence ID" value="ACA84462"/>
        <property type="gene ID" value="Swoo_0161"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0161"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030024_0_1_6"/>
    <dbReference type="OMA" id="FVAFGQQ"/>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765050" evidence="1">
        <location>
            <begin position="20"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="76"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="342" mass="38617" checksum="3B2FCF8A7C0BEABC" modified="2008-04-29" version="1" precursor="true">MFKSMLVILSAMICFSAQAAVILQYHHVSASTPAITSVTPEQFREQMQYLAENDFIVKPLSQVVDAIKAEQAIPDKTVVITFDDGYRSIAKTAHPILKEYGFPYTLFVSIEPIKAKYREMMSWEELVLLSKEGAEIANHSWAHEHLIRKLEGETQEKWLARVEENILKTEREIALATGQNHKMLAYPYGEYNQAIESMLARHGFIGLGQQSGAAGHYSSLTALPRFPVAGVYADLTSLKVKLHSLNMPVLSQNMSDPELKNGHWRPELKVTLDISDIYPHQMMCYIQGQGAKAPLWLSGNEFSIRAELDLPVGRSRYNCTVPSKSRTGYYWFSQAWVRSASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMB0</accession>
    <name>B1KMB0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-oxoadipyl-CoA thiolase</fullName>
            <ecNumber evidence="4">2.3.1.174</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_0222</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + succinyl-CoA = 3-oxoadipyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:19481"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57348"/>
            <dbReference type="EC" id="2.3.1.174"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Aromatic compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.174" evidence="4"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322872.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0222"/>
    <dbReference type="EnsemblBacteria" id="ACA84523">
        <property type="protein sequence ID" value="ACA84523"/>
        <property type="gene ID" value="Swoo_0222"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0222"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_2_2_6"/>
    <dbReference type="OMA" id="MSRVPMW"/>
    <dbReference type="OrthoDB" id="550338at2"/>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033812">
        <property type="term" value="F:3-oxoadipyl-CoA thiolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019619">
        <property type="term" value="P:3,4-dihydroxybenzoate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012793">
        <property type="entry name" value="PcaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02430">
        <property type="entry name" value="pcaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="13">
        <location>
            <begin position="275"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="10">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA84523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="400" mass="42361" checksum="0F63BF1F14AA398F" modified="2008-04-29" version="1">MKDVFIYDAVRTPIGRYGGALSGVRADDLGALPIKALMGRNPKVDWQNIEELFYGCANQAGEDNRNVARMSGLLAGLPITVPGVTLNRLCGSGMDAVGTAARAIKSGEMSLAIAGGVESMSRAPLVINKAEKGFDRKMELFDTTMGWRFINVALKAEYGVDSMPETAENVAEAFSVSRADQDKFAYRSQQKTAAAVDEGRFENEIVSVSVKRGKQHLEFDTDEHFRRETSIDGLSELSAPFREGGSVTAGNASGINDGACALLLGDAEAQALYGLTPLAKVTAMATSGVEPRLMGIGPVSASRKALALAGLKIEQMDVIELNEAFAAQALAVLRELGVDDDDARVNPNGGAIALGHPLGMSGARLVTTAAYELQRRKGKYALCTMCIGVGQGIAIVLERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMJ4</accession>
    <name>B1KMJ4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324338.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1707"/>
    <dbReference type="EnsemblBacteria" id="ACA85992">
        <property type="protein sequence ID" value="ACA85992"/>
        <property type="gene ID" value="Swoo_1707"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1707"/>
    <dbReference type="eggNOG" id="ENOG502Z9E6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042404_0_0_6"/>
    <dbReference type="OMA" id="TTNARPM"/>
    <dbReference type="OrthoDB" id="514419at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026950">
        <property type="entry name" value="Caps_assemb_Wzi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038636">
        <property type="entry name" value="Wzi_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14052">
        <property type="entry name" value="Caps_assemb_Wzi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764664" evidence="1">
        <location>
            <begin position="20"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="488" mass="54864" checksum="4FC9623EB137C0BB" modified="2008-04-29" version="1" precursor="true">MKIKLLSGFLLLGCSSVQAAWWVEPNDLSLRADIQLLSDTGVILQPITTYPLMWDGLKQDMDKAEQSQLNASQLSAFERVMAAYNEDHQSFNTKIELATASDPTRFIGFGQDYRDKAETSVSAEVTQDWFSGRLSASYHYDPIDGNSARLDNSFAAVMLGNWIVSAGAQQKYWGPGWDTGLIQTTNARPMPGITFSRNNSQAFETPWLNWVGPWTFTTSFSQMESDRYVPETKHWGARGTLRPISKLEVGFSWTMQWGGEGYGNSLSDWWDGLFNGGMSESEIENGQENMLAGYDFRWSDTAFGIPYGIYYERIHEDYHNGKNKLINASNMGGVDFVLASINTRIFIEYADTKASCGASDKIYNCMYEHGFYKSGYRYYGKSLGSTYDNDSETLVIGGITQLGGGQNITNKLRWLRLNTDGKDTSNPQGGNPVSPGEYERVYQIDTSYHRPFYEGTLKVGGTLGYSQYVHNGGNDWDTTIYAGWERRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ6</accession>
    <name>B1KMQ6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325770.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3163"/>
    <dbReference type="EnsemblBacteria" id="ACA87434">
        <property type="protein sequence ID" value="ACA87434"/>
        <property type="gene ID" value="Swoo_3163"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3163"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136125_0_0_6"/>
    <dbReference type="OMA" id="CHDNEHQ"/>
    <dbReference type="OrthoDB" id="1843957at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="28"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="120" mass="13962" checksum="7940313E6DE626B7" modified="2008-04-29" version="1">MSANQGQSKLDRVLAEAREYKAKRETGYREQALKLYPWVCGRCTREFNNANLRELTVHHRDHNHDNNPSDGSNWELLCLYCHDNEHSKFEELIQYGATKEAVVESATYNPFANLKGMMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV1</accession>
    <name>B1KMV1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325815.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3209"/>
    <dbReference type="EnsemblBacteria" id="ACA87479">
        <property type="protein sequence ID" value="ACA87479"/>
        <property type="gene ID" value="Swoo_3209"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3209"/>
    <dbReference type="eggNOG" id="COG3126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1905323_0_0_6"/>
    <dbReference type="OMA" id="VAMIQYQ"/>
    <dbReference type="OrthoDB" id="1635042at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039366">
        <property type="entry name" value="Pilotin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09619">
        <property type="entry name" value="YscW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767222" evidence="1">
        <location>
            <begin position="23"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="131" mass="14412" checksum="B7DB7500755257C9" modified="2008-04-29" version="1" precursor="true">MIKLMKSAVLICCLFLTACVTVQEEQPVIVNGAAGYLERINLPQGSSITIAIIDLDTPGAIMAQKSFDIARAPVPFKFILPADTVKDDVNYGVVAMIQYQGQVIFQTYDRFPVINNDKFTTEVLMKAVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMV2</accession>
    <name>B1KMV2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA thioesterase II</fullName>
            <ecNumber evidence="3">3.1.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325816.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3210"/>
    <dbReference type="EnsemblBacteria" id="ACA87480">
        <property type="protein sequence ID" value="ACA87480"/>
        <property type="gene ID" value="Swoo_3210"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3210"/>
    <dbReference type="eggNOG" id="COG1946">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032690_0_0_6"/>
    <dbReference type="OMA" id="SQVWFRT"/>
    <dbReference type="OrthoDB" id="990202at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102991">
        <property type="term" value="F:myristoyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016290">
        <property type="term" value="F:palmitoyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="PTHR11066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00189">
        <property type="entry name" value="tesB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="288" mass="32241" checksum="DC78FB62C90FFB7F" modified="2008-04-29" version="1">MSQVLDDLLALLSLEQIEVGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVAPTRQVHSFHSYFLRAGDEKQPIVYDVEIMRDGGSFSARRVKAIQKGRPIFYMTCSFQEHEEGFEHQALMPDVPGPDGLLNQQELAMTLRDKVPTKMLDKFMADSPIEMRLVDPQNPFNPKAREAKRHIWIRANGSVPSDHSVNEYLLAYASDFNFLVTAAQPHGVSFLTPGMRMATIDHAMWFHRPLDLNDWLLYSNESPNAGGGRGFVKGQFFNRQGQLVASATQEGLIRMKSDN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMW7</accession>
    <name>RL18_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplR</name>
        <name type="ordered locus">Swoo_4674</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327247.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMW7"/>
    <dbReference type="SMR" id="B1KMW7"/>
    <dbReference type="STRING" id="392500.Swoo_4674"/>
    <dbReference type="EnsemblBacteria" id="ACA88924">
        <property type="protein sequence ID" value="ACA88924"/>
        <property type="gene ID" value="Swoo_4674"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4674"/>
    <dbReference type="eggNOG" id="COG0256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098841_0_1_6"/>
    <dbReference type="OMA" id="NKQIYAQ"/>
    <dbReference type="OrthoDB" id="1963491at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142720" description="50S ribosomal protein L18">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <sequence length="116" mass="12690" checksum="F12CEAC3FEBFD27A" modified="2008-04-29" version="1">MDKKTSRLRRALRGRKKIQELGVNRLVVHRTPRHTYAQVISPDSQVLASASTAEKAVTEQLKYTGNVDAAKVVGKTVAERAIEKGVTVVAFDRSGFKYHGRVAALADAAREAGLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN45</accession>
    <name>B1KN45_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-propeller repeat TECPR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327319.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4753"/>
    <dbReference type="EnsemblBacteria" id="ACA89002">
        <property type="protein sequence ID" value="ACA89002"/>
        <property type="gene ID" value="Swoo_4753"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4753"/>
    <dbReference type="eggNOG" id="ENOG5030IYA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031876_0_0_6"/>
    <dbReference type="OrthoDB" id="1303819at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006624">
        <property type="entry name" value="Beta-propeller_rpt_TECPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19193">
        <property type="entry name" value="Tectonin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00706">
        <property type="entry name" value="TECPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765070" evidence="1">
        <location>
            <begin position="24"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42" evidence="2">
        <location>
            <begin position="57"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA89002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="601" mass="67100" checksum="1803A1C87EE2DE8C" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNE0</accession>
    <name>B1KNE0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP dicarboxylate transporter-DctP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324363.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1732"/>
    <dbReference type="EnsemblBacteria" id="ACA86017">
        <property type="protein sequence ID" value="ACA86017"/>
        <property type="gene ID" value="Swoo_1732"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1732"/>
    <dbReference type="eggNOG" id="COG1638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056493_0_0_6"/>
    <dbReference type="OMA" id="AQVLFCN"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766891" evidence="2">
        <location>
            <begin position="23"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="39186" checksum="8C4B068A22236EA4" modified="2008-04-29" version="1" precursor="true">MNVLSKIFFTSMLLLNTNAIFASDNNKAPSNVQIDNVNVSVVGTWSMLSQYKQFERPFWDETITENSNGAVIADVKGFNEMGLKGSEVVRLMKSGVIDFGSTVLGYLAADNPKNEAIDLAGLSPNIETAKIVSDAYKTELSELYNKTYDIKLLGLWPYSAQVLFCNVPITGLLDLKGKKIRTSNRTLAEFVGALGGVGVTMSFGEVVQSLQKGVVDCAITGSMSGYNAKWHEVTTHLYTLPLGWANVMHAVSNKAWNKLPKATKDYIEQEINGLESDIWKGAALETEQGIACNTGHGKCQSGEPASLILVEYTEGESMLLDNILSDHVLPLWAERCGKPCTNKWNETIGKAIGKDIDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNF1</accession>
    <name>B1KNF1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1743</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324374.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1743"/>
    <dbReference type="EnsemblBacteria" id="ACA86028">
        <property type="protein sequence ID" value="ACA86028"/>
        <property type="gene ID" value="Swoo_1743"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1743"/>
    <dbReference type="eggNOG" id="COG0122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_72_6_6"/>
    <dbReference type="OMA" id="RWPDAFP"/>
    <dbReference type="OrthoDB" id="1781735at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010316">
        <property type="entry name" value="AlkA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037046">
        <property type="entry name" value="AlkA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06029">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01009">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="9">
        <location>
            <begin position="93"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="501" mass="55939" checksum="6B647DE2CC4C4284" modified="2008-04-29" version="1">MCSEAEGVLTNESCRRARLARDPRFDGVFFIGVLTTGIFCRSICPATPPKEKNVRYFSTAIEAANAGLRPCLRCRPDSAPGSFAWKGTDTTVERALSLIDDGFLFGDSPGSLESLAQKLGITSRYLRKLFADKVGTSPNKYAQFRQLMFAKQLLHQTDLSMTQVGLAAGFTSIRRFNEVFQQTLALTPSALRKSRGSRQSELSHEGSEIRLSMQFSYRPPLNWQKQLDFYRLRMVEGMEWEADLEGYSRSFQLGDVKGFFEAKHDEVKHRFNVIIHLVDPQALPVLSEVVAQIKRVLDLDADMFQIQTSLSSIGIIKNSIVDGLRLPGTWSAFEAGCRAILGQQVSVVQATKLLNRLVEANGERLTISGREILLFPTPLAIANASLDELKMPGARKAALNAFGTFVSQHPDAPVDDWLNIKGIGPWTVAYAKMRGLSDPNILLCSDLIVKKRVLKRYEALQSSETDLKANLDISYKTITQQLEQSISPWGSYLTFQLWNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNK8</accession>
    <name>B1KNK8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ig domain protein, group 1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intimin/invasin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324431.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1801"/>
    <dbReference type="EnsemblBacteria" id="ACA86085">
        <property type="protein sequence ID" value="ACA86085"/>
        <property type="gene ID" value="Swoo_1801"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1801"/>
    <dbReference type="eggNOG" id="COG2831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006970_0_0_6"/>
    <dbReference type="OMA" id="FPDLNGN"/>
    <dbReference type="OrthoDB" id="416508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003344">
        <property type="entry name" value="Big_1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015217">
        <property type="entry name" value="Invasin_dom_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09134">
        <property type="entry name" value="Invasin_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51127">
        <property type="entry name" value="BIG1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767243" evidence="2">
        <location>
            <begin position="22"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Big-1" evidence="3">
        <location>
            <begin position="41"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Big-1" evidence="3">
        <location>
            <begin position="357"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="837" mass="85780" checksum="61C4041FEA937232" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNX4</accession>
    <name>B1KNX4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c-type protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Swoo_4756</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="9">Binds 4 heme groups per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Binds 4 heme groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NapC/NirT/NrfH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327322.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4756"/>
    <dbReference type="EnsemblBacteria" id="ACA89005">
        <property type="protein sequence ID" value="ACA89005"/>
        <property type="gene ID" value="Swoo_4756"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4756"/>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096753_2_0_6"/>
    <dbReference type="OMA" id="HIGMDTI"/>
    <dbReference type="OrthoDB" id="1683334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019333">
        <property type="term" value="P:denitrification pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024717">
        <property type="entry name" value="NapC/NirT/NrfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000013">
        <property type="entry name" value="4_hem_cytochrm_NapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_NNT" evidence="12">
        <location>
            <begin position="25"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>a menaquinol</name>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000013-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000013-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACA89005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="188" mass="21535" checksum="8A72E15B868A1BDE" modified="2008-04-29" version="1" precursor="true">MNNKGEKTRWQRLWSWLKRPLALGIPIGVFLLVLGATSFQGMMVVSNQNAFCFSCHLKMDTIVQEYKASSHFGDGETIPATCSDCHVPHPFIDKMIVKTIALKDVYHMMVGTITKENFEEHRPAMAESVWEDFKKNDSANCRYCHQGENFDLAKQPQRARLNHEKIAARGETCIDCHQGLTHKRIVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPC6</accession>
    <name>B1KPC6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323045.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0397"/>
    <dbReference type="EnsemblBacteria" id="ACA84696">
        <property type="protein sequence ID" value="ACA84696"/>
        <property type="gene ID" value="Swoo_0397"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0397"/>
    <dbReference type="eggNOG" id="ENOG5033C2S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169030_0_0_6"/>
    <dbReference type="OMA" id="MKYVASC"/>
    <dbReference type="OrthoDB" id="2031630at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="10838" checksum="80CFB7D0E139E495" modified="2008-04-29" version="1" precursor="true">MRLVLLGFLLSLLTACTQNPEWTLFYYPDEPQIPADAELGEHISGYYGTSEQCLLKGAGMVKLSDSGIGSYQCGHLCVAKEQNDLSCQTYLDSLIPTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPM0</accession>
    <name>B1KPM0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324519.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1889"/>
    <dbReference type="EnsemblBacteria" id="ACA86173">
        <property type="protein sequence ID" value="ACA86173"/>
        <property type="gene ID" value="Swoo_1889"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1889"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_778206_0_0_6"/>
    <dbReference type="OMA" id="EYACSSH"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="44"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="349" mass="39387" checksum="96403F764D09A008" modified="2008-04-29" version="1">MDQAEALMKRLPVIVIKELEQLGLIFGSNHESDKAGSSTLEALKLTHGLSNQNYLIDNGQHKWVLRCNSSASDQLCNRRAEVRNWRLAAEAGIAPALLYVSTDHSFYLSEYIDEEPTKRWANMLSAETAHPVIHDTAIWPDADKQLLLLLQGFTSLDTPENITDNPEQWRLYFKRLSEIEACIVSEASSGENAQWCTHFKQLSSLESKISQWLHELSDCALGLQYSHRDLNPHNLLCKDGTLYCIDFEYACGSHPLFDLASVLSTHKLSTPQRQRLIDAYLLNHPKLTSDAKAALPAAINIYWVFAASWSLLMASDNSANSDMKNLSNSNPHQAQEYLNCFEQFFSLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPN3</accession>
    <name>B1KPN3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Membrane-fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324532.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1902"/>
    <dbReference type="EnsemblBacteria" id="ACA86186">
        <property type="protein sequence ID" value="ACA86186"/>
        <property type="gene ID" value="Swoo_1902"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1902"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_14_2_6"/>
    <dbReference type="OMA" id="DSPVNYF"/>
    <dbReference type="OrthoDB" id="1532186at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="419" mass="46766" checksum="696DE886DAD9FE6C" modified="2008-04-29" version="1" precursor="true">MSECQFSFTKSVNGAFNLSRNLMKSSVLIAMLALSGCSQQASDGVLTMDVQRADFTFDIPAAGELEASNATAVTVPSGLRGPQSLAWILANFTQVEAGDVVARMDPERENYRLKMEQFDFDKLAFDSQIQTEKDNTISQNLLEGTQITSQEKDLAERYFSDDERVYNKIEIIDQMRNQDYLVAKMHYFDWGLEQHGSQAEAEQELIKLRQKGHSAKISRYESNLNQMEIIAPHDGLFVYQAGWDGSFPVVGDMMWSGTSIGLLPDTSVMQAKLYVQESEAAGLAVGKKATVYLDAYPDKPFTGEVTQLDALAKPKDKDSPVNYFQFTISLDRTEVGIMQPGRQVQAKVHMLSLHSVLTVPNQALFQKEGQYWVYLKTAEGFVKQTVEMGSRSLNRTEITKGLSEGDVIALTTPPKRSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPN7</accession>
    <name>B1KPN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324536.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86190">
        <property type="protein sequence ID" value="ACA86190"/>
        <property type="gene ID" value="Swoo_1906"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1906"/>
    <dbReference type="eggNOG" id="ENOG5030WCS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1234321_0_0_6"/>
    <dbReference type="OMA" id="NRINIAG"/>
    <dbReference type="OrthoDB" id="2125995at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765112" evidence="1">
        <location>
            <begin position="22"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="224" mass="24631" checksum="C4204D7115672E37" modified="2008-04-29" version="1" precursor="true">MNIKRNLALVSLFIVAGTASAHQLAFDKLTPSHKRMQTVVSFELNEEEIINQYHFRAKYFDIEKWMMSKNLVLKADHLTNGEVAHHGVHTKQLEQPELTLSAQGGIHHTVDPFNRLNSVAGSSGGELNSVVNRVNIAGLVAVSICNAYTSVNIKQASYHLTPKFTAPVSLLQGINPSTAELSDYSLSEGVKFSCVHPIDVANPLPRESIKDVKQLKYGTASKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPP1</accession>
    <name>B1KPP1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Anaerobic C4-dicarboxylate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_1910</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 8">Cell inner membrane</location>
            <topology evidence="3 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324540.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1910"/>
    <dbReference type="EnsemblBacteria" id="ACA86194">
        <property type="protein sequence ID" value="ACA86194"/>
        <property type="gene ID" value="Swoo_1910"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1910"/>
    <dbReference type="eggNOG" id="COG2704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036056_1_1_6"/>
    <dbReference type="OMA" id="PKQINYL"/>
    <dbReference type="OrthoDB" id="591678at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015556">
        <property type="term" value="F:C4-dicarboxylate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004668">
        <property type="entry name" value="Anaer_Dcu_memb_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36106">
        <property type="entry name" value="PTHR36106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03605">
        <property type="entry name" value="DcuA_DcuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004539">
        <property type="entry name" value="C4-dicrbxl_trns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00770">
        <property type="entry name" value="Dcu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR004539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="45291" checksum="F70174C03490D56F" modified="2008-04-29" version="1">MVVVELLVVLAFIYLGARIGGIGIGLAGGAGVLVLSLFLGVDTGHIPIDVILIIMSVIAAIAAMQVAGGLELLVDLSERFLRKHPKRITFYAPIVTYFMTLLAGTGHTAFSTLPVIAEVAKEQGIRPSRPLGISVVASQIAITASPISAAVVFFSGILEPLGVGYLTLLAICIPTTFAACMIGAFVSNFLGCELKDDPVFLERQAKGLIKLQGQTQRNLLPTAKTATAIFVTAIVGVIVYATLISDTVNLIQDPALGRNEAIMVFMLAAATAIVTITKIDPSEISNAPTFKSGMCACICVLGVAWLGDTFVSSHITEIKALSADILNQYPWMLAVTLFFASMLLYSQGATTTALMPAALAIGVAPITAIASFAAVSALFVLPTYPTLLAAVEMDDTGSTRIGKMVFNHPFLIPGLVTIFTSVALGFALGSLVL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-06-10" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ25</accession>
    <name>Y4889_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0597 protein Swoo_4889</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_4889</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0597 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327455.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ25"/>
    <dbReference type="SMR" id="B1KQ25"/>
    <dbReference type="STRING" id="392500.Swoo_4889"/>
    <dbReference type="EnsemblBacteria" id="ACA89138">
        <property type="protein sequence ID" value="ACA89138"/>
        <property type="gene ID" value="Swoo_4889"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4889"/>
    <dbReference type="eggNOG" id="COG3681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051840_0_0_6"/>
    <dbReference type="OMA" id="GAMIPVM"/>
    <dbReference type="OrthoDB" id="1326279at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01845">
        <property type="entry name" value="UPF0597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021144">
        <property type="entry name" value="UPF0597"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30501">
        <property type="entry name" value="PTHR30501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006054">
        <property type="entry name" value="UCP006054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000339856" description="UPF0597 protein Swoo_4889">
        <location>
            <begin position="1"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01845"/>
        </source>
    </evidence>
    <sequence length="425" mass="44323" checksum="A454653461B63498" modified="2008-04-29" version="1">MKPVWQKYIEIINQVVKPALGCTEPIAAAYGAAVAVQELGCSVPDSLEVFVSDNLYKNSMGVFVPGTGKIGLAIAAASGAIGGNADAGLEVLAAITPEQVLQAQEMIDAGKVSVKRTVTDEFIYCCVIAKFEGRESLVKICGGHTLIVEKQLNGKINFIADESSATSTGSICEGVDINIASIYEFATQVELEKIAFILQAADLNTKLSDEGMTNSYGLEVGRTMKKSIDEGILSNDLLNKIVMETAAASDARMGGATLPAMSNLGSGNQGIAATIPVVIAAKHYKNSDEQLARALILSHLGAIYIKSHYPPLSAFCGNTVTSAAAAMAMVYLAGGSFEQSCFAIQNVISDSSGMVCDGAKASCAMKVSTSSCAAVRAFLMAMNSRSVSGQGIIAKDVEQTIINIGQMISHGMPSTDTTIINIMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ26</accession>
    <name>B1KQ26_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327456.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4890"/>
    <dbReference type="EnsemblBacteria" id="ACA89139">
        <property type="protein sequence ID" value="ACA89139"/>
        <property type="gene ID" value="Swoo_4890"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4890"/>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052043_3_0_6"/>
    <dbReference type="OMA" id="FPGSWAT"/>
    <dbReference type="OrthoDB" id="369689at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="433" mass="47418" checksum="062FB3E4B806D997" modified="2008-04-29" version="1">MTASIATVEISRDTSTAAEWKEATRFDSTDWGWIVMSIGMAIGAGIVFLPIQVGVMGLWVFLLSSIIGYPAMYLFQKLFINTLAESKKCTDYPGVISGYLGKNWGVALGVLYFLMLVIWVLVYSLAVTNDSASYLHSFGVTEGDLSDNVFYGLGLICVLVFIGSKGEKLLFKLSGFMAVTVLCLVGVMGVLLIARWDINNIPEMGQFGSMMKDAIITLPFTLTSILFIQSLSPMVISYRAHEKSIEVARYKSTRAMTIAFSLLFVIVFFFAVSFTFAISQEQATEAMNKNISALAIIAHYFPGSWATITGVVINIFAIVTSFFGVFLAFKEACKGLAMNLLLRKFKESQVNKAKVDKLVTVFIILLAWSAIALNAPILSFTSICSPIFGLVGCLIPAYLVYKVPQLNKYKGPATNFIIITGVLLCISPFIAFS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ68</accession>
    <name>RL34_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmH</name>
        <name type="ordered locus">Swoo_4932</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ68"/>
    <dbReference type="SMR" id="B1KQ68"/>
    <dbReference type="STRING" id="392500.Swoo_4932"/>
    <dbReference type="PRIDE" id="B1KQ68"/>
    <dbReference type="EnsemblBacteria" id="ACA89181">
        <property type="protein sequence ID" value="ACA89181"/>
        <property type="gene ID" value="Swoo_4932"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4932"/>
    <dbReference type="eggNOG" id="COG0230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129938_2_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000196110" description="50S ribosomal protein L34">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="45" mass="5170" checksum="B4E7ED470B3FD8C8" modified="2008-04-29" version="1">MSKRTFQPSTLKRKRSHGFRARMATVSGRKVLARRRAKGRARLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ78</accession>
    <name>B1KQ78_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase like protein, AhpD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323082.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0435"/>
    <dbReference type="EnsemblBacteria" id="ACA84733">
        <property type="protein sequence ID" value="ACA84733"/>
        <property type="gene ID" value="Swoo_0435"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0435"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_5_0_6"/>
    <dbReference type="OMA" id="DYCLSAH"/>
    <dbReference type="OrthoDB" id="1925754at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="51"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="178" mass="18922" checksum="A3AB9DDBB1B7AC5D" modified="2008-04-29" version="1">MANLHPVEIASASDAQQLLFKKVEGAFGAVPNMFRTIGHSSAALESMWTSFGALGKGSISPALGEQIAVLVADINRCEYCLSAHTVLGKNAGVTKEEMELAQRGVSNDLKVQAALDFAKKLVTQHGQVSRDDIGLVKGAGFSDAELTEILAHVALNIFTNYTNVAFDVEVDFPKVSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQB2</accession>
    <name>B1KQB2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase with GAF sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323116.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0469"/>
    <dbReference type="EnsemblBacteria" id="ACA84767">
        <property type="protein sequence ID" value="ACA84767"/>
        <property type="gene ID" value="Swoo_0469"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0469"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_32_6"/>
    <dbReference type="OMA" id="FVSHHIA"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="481"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="623"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="411"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA84767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="874" mass="99558" checksum="F1F257EACD8360FF" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQD1</accession>
    <name>B1KQD1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323135.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0488"/>
    <dbReference type="EnsemblBacteria" id="ACA84786">
        <property type="protein sequence ID" value="ACA84786"/>
        <property type="gene ID" value="Swoo_0488"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0488"/>
    <dbReference type="eggNOG" id="COG3159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073320_0_0_6"/>
    <dbReference type="OMA" id="FQVPFVS"/>
    <dbReference type="OrthoDB" id="1264777at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007435">
        <property type="entry name" value="DUF484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38765">
        <property type="entry name" value="PTHR38765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04340">
        <property type="entry name" value="DUF484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="212" mass="24542" checksum="611B1AC815B93500" modified="2008-04-29" version="1">MTKASKEKTPAPFDELLIREFLLDNPDFFNRYPELLLAMQIPHAERGAISLIERKQEMFRNRVQQLEEEITSLLGMASRNEMIYMFNTALSLKLLKCEDLGELRQVLSEGLKTQFHFSHVRLITVHDIDSELSQIWSKRLNQGYYFGRLTMSESKRLFGSEVGSVALSRLSEECGQVIFAIASQDAMHFHPEMDNLLLDQLKQLLDHLLPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQE2</accession>
    <name>B1KQE2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323146.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0500"/>
    <dbReference type="EnsemblBacteria" id="ACA84797">
        <property type="protein sequence ID" value="ACA84797"/>
        <property type="gene ID" value="Swoo_0500"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0500"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1401">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388755_0_0_6"/>
    <dbReference type="OMA" id="DNESAHV"/>
    <dbReference type="OrthoDB" id="489714at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="2">
        <location>
            <begin position="323"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="712" mass="81033" checksum="D80B027A1A91C2A0" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQN7</accession>
    <name>B1KQN7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324622.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1992"/>
    <dbReference type="EnsemblBacteria" id="ACA86276">
        <property type="protein sequence ID" value="ACA86276"/>
        <property type="gene ID" value="Swoo_1992"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1992"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_3_6"/>
    <dbReference type="OMA" id="ARIWMIG"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="254" mass="29033" checksum="4804CF98036019E2" modified="2008-04-29" version="1">MTLELRDTSIIKDFPKAVIFDTDNTLYPYHYSHQQASLAVQQKAEKILGIKQSRFSDALKISKREIKERLGETASSHSRLLYFQRTIELLGLKTQIMTTLDLEQTYWRTFLTNSQLFPEMHEFLHDLRAHGIQSAVVTDLTAQIQFRKLVYFGLHEAFDYIVTTEEAGADKPNPLPFQLARSKLGLEKGDNLWMIGDHPVKDIQGAKKTLGAITLQKNHKDVKVLKGKEGPDILFDKYSELRELLGEISSNKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQR8</accession>
    <name>B1KQR8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326009.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3406"/>
    <dbReference type="EnsemblBacteria" id="ACA87674">
        <property type="protein sequence ID" value="ACA87674"/>
        <property type="gene ID" value="Swoo_3406"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3406"/>
    <dbReference type="eggNOG" id="COG1574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_1_0_6"/>
    <dbReference type="OMA" id="VAWVGSE"/>
    <dbReference type="OrthoDB" id="751534at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767567" evidence="1">
        <location>
            <begin position="24"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="2">
        <location>
            <begin position="73"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="550" mass="60334" checksum="55C890F621FE9219" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR02</accession>
    <name>B1KR02_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tatC</name>
        <name evidence="7" type="ordered locus">Swoo_0522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323167.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0522"/>
    <dbReference type="EnsemblBacteria" id="ACA84819">
        <property type="protein sequence ID" value="ACA84819"/>
        <property type="gene ID" value="Swoo_0522"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0522"/>
    <dbReference type="eggNOG" id="COG0805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031942_1_1_6"/>
    <dbReference type="OMA" id="EMSFLDH"/>
    <dbReference type="OrthoDB" id="1848013at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019820">
        <property type="entry name" value="Sec-indep_translocase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01218">
        <property type="entry name" value="TATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="28651" checksum="12EBF09EB914C7D1" modified="2008-04-29" version="1" precursor="true">MSQQQPLISHLLELRTRLLRAIASVILVFACMAYWSNDIYHYVATPLMDVMPEASSMIATDVAAPFFAPFKLTLVLAFFIAIPYVLFQIWSFIAPGLYKHEKRLMMPLLASSTLLFYLGIAFAYYVVFPVVFGFFTSVAPEGVQVATDITSYLSFILKLFFAFGLAFEIPIAVVLLCWAGVTTPDDLKAKRPYIIVGAFVIGMLLTPPDIISQTMLAVPMLILFEGGLIAARFYSKKDEEDEDEQEKQDEPGQEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR46</accession>
    <name>B1KR46_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0567</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323211.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0567"/>
    <dbReference type="EnsemblBacteria" id="ACA84863">
        <property type="protein sequence ID" value="ACA84863"/>
        <property type="gene ID" value="Swoo_0567"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0567"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029002_0_1_6"/>
    <dbReference type="OMA" id="EMGHHAY"/>
    <dbReference type="OrthoDB" id="1530824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="161"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="333" mass="36735" checksum="3781472B517488EB" modified="2008-04-29" version="1">MAPQNSTKHAAELTLGSNGYLILKSEAHQHQCQLEEVTLSDAIGSMPRSITFSTGWVFISSDGNKLNSWLNSHCKTPLLVKLERNLLLIFLASIITLLTAYGLYVYGVPKAAKFIANQLPVELSTELGDQGLTMLNKMGFEESKLELQERQKLRQRFDLLIEKLSNQGVEFKHRPKIEFRYADGGANAFALADGTIILTDAMVKLANEKMELEGVILHELGHVHHNHVMTNMVQTAILSITAAMVIGDSSGISDTLASIAVLGGGLTYSRIHENEADNFAAHQLYSRLQSAAPLADLFEKLQEQQAVDLPSWSSTHPALSERVDTLRSYKPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR73</accession>
    <name>B1KR73_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323238.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0594"/>
    <dbReference type="EnsemblBacteria" id="ACA84890">
        <property type="protein sequence ID" value="ACA84890"/>
        <property type="gene ID" value="Swoo_0594"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0594"/>
    <dbReference type="HOGENOM" id="CLU_2883446_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767583" evidence="1">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="63" mass="6777" checksum="CB93A3C2246A79D9" modified="2008-04-29" version="1" precursor="true">MKKQLTTILLILSISWLAALSGASAAEYDERGGSRGDNHFQLIYSDGSGEHAGVTYESLVPHI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-11-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX0</accession>
    <name>TSAC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="1">TC-AMP synthase</shortName>
            <ecNumber evidence="1">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA threonylcarbamoyladenosine biosynthesis protein TsaC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tsaC</name>
        <name type="synonym">rimN</name>
        <name type="ordered locus">Swoo_0044</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUA5 family. TsaC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322694.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KCX0"/>
    <dbReference type="SMR" id="B1KCX0"/>
    <dbReference type="STRING" id="392500.Swoo_0044"/>
    <dbReference type="EnsemblBacteria" id="ACA84345">
        <property type="protein sequence ID" value="ACA84345"/>
        <property type="gene ID" value="Swoo_0044"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0044"/>
    <dbReference type="eggNOG" id="COG0009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031397_6_0_6"/>
    <dbReference type="OMA" id="LVDAFWP"/>
    <dbReference type="OrthoDB" id="1913202at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01852">
        <property type="entry name" value="TsaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023535">
        <property type="entry name" value="TC-AMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF8">
        <property type="entry name" value="PTHR17490:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000352990" description="Threonylcarbamoyl-AMP synthase">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01852"/>
        </source>
    </evidence>
    <sequence length="185" mass="20101" checksum="C246267C3A30CC37" modified="2008-04-29" version="1">MLEQAPAEVKQVIESGGVVAYPTEAVYGLGCDPDNDAAITKLLAIKKRPWEKGLILVASDYQQLLPYIDDSQLTEEQRERVFSKWPGPFTFIMPIKPGISNLLCGSFNSLAVRVSDHPTIQAICQQLGKPLVSTSANHSGEEPAMSHEEILAKFEGEIDALVAGSLGEQRKPSTIIDAISGKILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD11</accession>
    <name>B1KD11_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0057</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="4">Binds 2 heme c groups covalently per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322707.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0057"/>
    <dbReference type="EnsemblBacteria" id="ACA84358">
        <property type="protein sequence ID" value="ACA84358"/>
        <property type="gene ID" value="Swoo_0057"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0057"/>
    <dbReference type="eggNOG" id="COG2863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076280_2_1_6"/>
    <dbReference type="OMA" id="MMRDVAK"/>
    <dbReference type="OrthoDB" id="1853490at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024167">
        <property type="entry name" value="Cytochrome_c4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000005">
        <property type="entry name" value="Cytochrome_c4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764693" evidence="7">
        <location>
            <begin position="21"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="22"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="115"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="206" mass="21748" checksum="08C28AFEF7719477" modified="2008-04-29" version="1" precursor="true">MKKLALALSVLASISSPAMAEGNAEAGKTKAVVCSACHGVDGNSMIDMYPKLAGQQATYLEKQMRDFRSAAQTGGKEGRNDPIMGGMAMMLSDQDIKDVAAFYASQTQTQVEVADIPELGEQLYKSGDVARGITACIACHGPSGAGSELAGFPAIGGQHANYLTIQINKFRDTSRNNDLNGMMQDIASKLTTEDAEALSKYISSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD46</accession>
    <name>B1KD46_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Na(+)-translocating NADH-quinone reductase subunit A</fullName>
            <shortName evidence="2">Na(+)-NQR subunit A</shortName>
            <shortName evidence="2">Na(+)-translocating NQR subunit A</shortName>
            <ecNumber evidence="2">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NQR complex subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NQR-1 subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nqrA</name>
        <name evidence="4" type="ordered locus">Swoo_3617</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NqrA family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3617"/>
    <dbReference type="EnsemblBacteria" id="ACA87881">
        <property type="protein sequence ID" value="ACA87881"/>
        <property type="gene ID" value="Swoo_3617"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3617"/>
    <dbReference type="eggNOG" id="COG1726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046656_0_0_6"/>
    <dbReference type="OMA" id="IKQRPYD"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00425">
        <property type="entry name" value="NqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008703">
        <property type="entry name" value="NqrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022615">
        <property type="entry name" value="NqrA_C_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37839">
        <property type="entry name" value="PTHR37839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05896">
        <property type="entry name" value="NQRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11973">
        <property type="entry name" value="NQRA_SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01936">
        <property type="entry name" value="nqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0915">Sodium</keyword>
    <keyword evidence="2" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 2" id="KW-0813">Transport</keyword>
    <keyword evidence="2 4" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NQRA_SLBB" evidence="3">
        <location>
            <begin position="287"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA87881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="472" mass="50953" checksum="E971B1FF14415A36" modified="2008-04-29" version="1">MRWAWYFPCHLLQERGALSFLHNVVLVDMITIKKGLDLPLAGGPEQVIHNGPAIKRVATLGEEYIGLRPTMKIKVGDKVKKGQIIFEDKKNLGVKYTASASGTVVEINRGAQRVLQSVVIEAEGNECVSFAKYDTAQLDTLDAQLVRDNLIESGLWTAMRTRPFSKAPAVDSTAAGIFVTAIDTQPLAANPEVVIGEHKDDFANGLKVLARLTEGKVYLCKAPGADIPAANAQVEEFAGGHPAGLPGTHIHFLLSASANRTVWHVGYQDVIAIGQLFTTGELNSERVVAVVGPKALKPRLIRTQVGASTAELTAGEIADGEVRVVSGSVLSGRTAVGPHAYLGRFHQQVSLLEEGREQEFIGWAMPGAEKYSITRAFLGHLSPSRLFKMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDFDGAASLGALELDEEDLALCTFVCPGKYDYATYLRDCLDTIVREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD51</accession>
    <name>B1KD51_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BolA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326219.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3622"/>
    <dbReference type="EnsemblBacteria" id="ACA87886">
        <property type="protein sequence ID" value="ACA87886"/>
        <property type="gene ID" value="Swoo_3622"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3622"/>
    <dbReference type="eggNOG" id="COG0271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109462_3_1_6"/>
    <dbReference type="OMA" id="CLGGFGK"/>
    <dbReference type="OrthoDB" id="1981704at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="99" mass="10935" checksum="E188F9D8958E9F81" modified="2008-04-29" version="1">MSVAQSIIEHLTASLSPTHLEVINESHNHHVPPNSETHFKVIITSEFFEGKRLLARHRAVNEALATEFANGLHALSMHTYSPDEWAAEVAVPDSPKCKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDB9</accession>
    <name>B1KDB9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_0624</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323267.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0624"/>
    <dbReference type="EnsemblBacteria" id="ACA84920">
        <property type="protein sequence ID" value="ACA84920"/>
        <property type="gene ID" value="Swoo_0624"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0624"/>
    <dbReference type="eggNOG" id="COG0685">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025841_0_0_6"/>
    <dbReference type="OMA" id="EMHPQAR"/>
    <dbReference type="OrthoDB" id="1425269at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004620">
        <property type="entry name" value="MTHF_reductase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00676">
        <property type="entry name" value="fadh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="6 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA84920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="33041" checksum="7C1042DA85BAB471" modified="2008-04-29" version="1">MSFNHAQHSTSLNQSLAELNGDINVSFEFFPPASPEMEQLLWNSIRRLEPLNPKFVSVTYGANSGVRDRTHGVIERIQKETDLVAAPHLTLVDASDEELKELAKHYWNSGIKDIVALRGDLPEGSPKPTRFANDLVGLLRSVADFDISVAAYPEVHPDARNAQADLINLKKKIDAGANRAITQFFFDVESYLRFRDRCVTAGIDVEIVPGILPVTNFKQLKRFAGMTNVGIPGWLHKQFEGLDDDPVTRQMVGANVAIDMVKVLSREGVKDFHFYTLNRAELTYAICHTLGVRPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDF9</accession>
    <name>B1KDF9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323307.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0664"/>
    <dbReference type="EnsemblBacteria" id="ACA84960">
        <property type="protein sequence ID" value="ACA84960"/>
        <property type="gene ID" value="Swoo_0664"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0664"/>
    <dbReference type="eggNOG" id="ENOG5032NVF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1991163_0_0_6"/>
    <dbReference type="OMA" id="CHPPMEL"/>
    <dbReference type="OrthoDB" id="2013865at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764307" evidence="1">
        <location>
            <begin position="25"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="13418" checksum="F825729C957E0ECD" modified="2008-04-29" version="1" precursor="true">MQSNLTLVLLLVVFVSQLFPTCVASDIHINEQTSQESQQISMTSSDGEQESCCHQQGHVCGHARTATEQDEHDDDFHTSCHPPMELSFFNHLNHSQDNYLFAVHYQNRSYAPPIPPPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDM4</accession>
    <name>B1KDM4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324766.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2137"/>
    <dbReference type="EnsemblBacteria" id="ACA86421">
        <property type="protein sequence ID" value="ACA86421"/>
        <property type="gene ID" value="Swoo_2137"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2137"/>
    <dbReference type="eggNOG" id="ENOG502Z7HQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048734_0_0_6"/>
    <dbReference type="OMA" id="HRVWVVK"/>
    <dbReference type="OrthoDB" id="451285at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010752">
        <property type="entry name" value="DUF1329"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07044">
        <property type="entry name" value="DUF1329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766478" evidence="1">
        <location>
            <begin position="23"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="454" mass="51164" checksum="347DDC822FF34D46" modified="2008-04-29" version="1" precursor="true">MKKLGILSAAVMVALSAPSAIAKVTDAEAAKLGTELTPMGGVKAANADGSIPAWDGGITSAIAGYEKGMHHPDPFPQDKIEFTITNGNKDKYKANLTEGQMKLFELYPDTFKMNVYQTRRTASVPQFVYDATKANATRAELVSDGNGIKGASIGVPFPIPQNGLEVIWNHVLRFRGVDVETARSQVAPTAGGGYTLVETAEEIRFQYSRPEMTLDKLNASNTLFYFKQVVTQPARLAGTALLVKETMDQEALPRQAWTYNTGQRRVRKAPNVAFDTPGSVSDGLRTTDDFDMFNGSPVRYNWELVGKQEVYIPYNDYKLHSDKLKYDQIIQPGHINPEFVRWEKHRVWVVKAQLKEGMRHIYKTRTFYIDEDSWQVSLADMYDNRDELYRVAFAHGINYYEVPTHWSTLEVFHDLQSRRYLAMGLDNEGRMYNFDAKLSEANFTPAALRRAGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDN4</accession>
    <name>B1KDN4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome modulation factor</fullName>
            <shortName evidence="1">RMF</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rmf</name>
        <name evidence="2" type="ordered locus">Swoo_2147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribosome modulation factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324776.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2147"/>
    <dbReference type="EnsemblBacteria" id="ACA86431">
        <property type="protein sequence ID" value="ACA86431"/>
        <property type="gene ID" value="Swoo_2147"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2147"/>
    <dbReference type="eggNOG" id="COG3130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_203350_0_0_6"/>
    <dbReference type="OMA" id="EACPYQQ"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00919">
        <property type="entry name" value="RMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007040">
        <property type="entry name" value="Ribosome_modulation_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023200">
        <property type="entry name" value="RMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04957">
        <property type="entry name" value="RMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="58" mass="6572" checksum="095AD57ABAD017C7" modified="2008-04-29" version="1">MKRQKRDRLDRAFSKGFQAGVGGRSKENCPYSTLDSKSHWLGGWREGVDGRLSGLFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDP1</accession>
    <name>B1KDP1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2154"/>
    <dbReference type="EnsemblBacteria" id="ACA86438">
        <property type="protein sequence ID" value="ACA86438"/>
        <property type="gene ID" value="Swoo_2154"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2154"/>
    <dbReference type="eggNOG" id="COG3108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080400_1_2_6"/>
    <dbReference type="OMA" id="KSYHMKG"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010275">
        <property type="entry name" value="DUF882"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37425">
        <property type="entry name" value="PTHR37425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05951">
        <property type="entry name" value="Peptidase_M15_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="171" mass="19048" checksum="E9E630DE6780FFAD" modified="2008-04-29" version="1" precursor="true">MLGLSGVAMFSVIPSKVQASRSTTGVRSLGFNNLHTGERGFGSYWIDGNYQEKTLSEFSHTLRDHRRNESAPMDKRLYDLLFKLKLSLNVEEDFNVISGYRSPQTNAMLASKNNGVAKKSYHMKGMAMDIALPNVNLSDLRDAAIELKLGGVGYYPRSGFIHVDTGPVRTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDR6</accession>
    <name>B1KDR6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324807.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2181"/>
    <dbReference type="EnsemblBacteria" id="ACA86463">
        <property type="protein sequence ID" value="ACA86463"/>
        <property type="gene ID" value="Swoo_2181"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2181"/>
    <dbReference type="eggNOG" id="ENOG5030QV5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180832_1_0_6"/>
    <dbReference type="OrthoDB" id="2085508at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021550">
        <property type="entry name" value="DUF2897"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11446">
        <property type="entry name" value="DUF2897"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="86" mass="9705" checksum="EDD13370FF620286" modified="2008-04-29" version="1">MTDLETWLIIILVVGVIASNLAVLKYSAKFKMTQFGKDHKKSANSHDDAQGKQSNDSQQDKQTDPEKKQSNTESKKDDDKDSDGFW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-26" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDS3</accession>
    <name>DAPE_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Succinyl-diaminopimelate desuccinylase</fullName>
            <shortName evidence="1">SDAP desuccinylase</shortName>
            <ecNumber evidence="1">3.5.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dapE</name>
        <name type="ordered locus">Swoo_2188</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + succinate</text>
            <dbReference type="Rhea" id="RHEA:22608"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:58087"/>
            <dbReference type="EC" id="3.5.1.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) or Co(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family. DapE subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324814.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDS3"/>
    <dbReference type="SMR" id="B1KDS3"/>
    <dbReference type="STRING" id="392500.Swoo_2188"/>
    <dbReference type="EnsemblBacteria" id="ACA86470">
        <property type="protein sequence ID" value="ACA86470"/>
        <property type="gene ID" value="Swoo_2188"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2188"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_4_0_6"/>
    <dbReference type="OMA" id="LNSHHDT"/>
    <dbReference type="OrthoDB" id="275025at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01690">
        <property type="entry name" value="DapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005941">
        <property type="entry name" value="DapE_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01246">
        <property type="entry name" value="dapE_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0170">Cobalt</keyword>
    <keyword id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0457">Lysine biosynthesis</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000375744" description="Succinyl-diaminopimelate desuccinylase">
        <location>
            <begin position="1"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01690"/>
        </source>
    </evidence>
    <sequence length="376" mass="40858" checksum="00F130406A0EB690" modified="2008-04-29" version="1">MSQEVLTLAQDLISRPSVTPLDEGCQTLMAERLAAQGFEIESMVFEDTTNMWARRGKEGPLFCFAGHTDVVPVGDLNRWHTPPFDPVVIDGYLHGRGAADMKGSLAAMVVATERFVEKHPDHNGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWSLVGEPSSTHKLGDIVKNGRRGSLTGNLTINGIQGHVAYPHLADNPIHKAAPALDELARMKWDNGNEFFPPTSFQIANINGGTGASNVIPGALEVMFNFRYSTEVTAEILIQRVLNILDAHGLDYDISWIFNGLPFLTGDGPLLDATREAIKQVTGSDTDPQTSGGTSDGRFIAPTGAHVIELGPVNATIHKVNECVKVSDLELLTQCYEVILEKLLC</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDW0</accession>
    <name>SYL_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="1">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuS</name>
        <name type="ordered locus">Swoo_3702</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326294.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KDW0"/>
    <dbReference type="SMR" id="B1KDW0"/>
    <dbReference type="STRING" id="392500.Swoo_3702"/>
    <dbReference type="EnsemblBacteria" id="ACA87962">
        <property type="protein sequence ID" value="ACA87962"/>
        <property type="gene ID" value="Swoo_3702"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3702"/>
    <dbReference type="eggNOG" id="COG0495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004427_0_0_6"/>
    <dbReference type="OMA" id="TFMVLAP"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000091363" description="Leucine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="618"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="621"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <sequence length="859" mass="97372" checksum="F83A898A01DEE481" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE10</accession>
    <name>B1KE10_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326344.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3753"/>
    <dbReference type="EnsemblBacteria" id="ACA88012">
        <property type="protein sequence ID" value="ACA88012"/>
        <property type="gene ID" value="Swoo_3753"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3753"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038666_0_0_6"/>
    <dbReference type="OMA" id="SQFRIFA"/>
    <dbReference type="OrthoDB" id="837523at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045748">
        <property type="entry name" value="DcaP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19577">
        <property type="entry name" value="DcaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767280" evidence="1">
        <location>
            <begin position="21"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="344" mass="38655" checksum="5F79B989972B83C0" modified="2008-04-29" version="1" precursor="true">MKTSTLALITLGLFSSSSYAAFEFDLGEDNKLKFGGYLKADVRHVSGEVPYRPFWIATGATGEDSSQTNFTMRESRFNASYTHGKVMGFVEMDFYGSDGSEAVVNNYDPRLRHAFIKYDNWLVGQTWSTFMPLTAIPETLDFGGPHVGEAFIRQTQIRYTYGGFQFALENPETTGADNKNDAIPDIVGRYIHKADWGELGVAALVRQLDSDGIDKTTAAFNLYGKLLIGERDDFRFQVNVGESGRYVAPGLTTDIIPDGDNSVPEETTAYYAAYRHFWSESYRSTLFYGHAETDIQNRERQMWGVNLIKQLTPHLWTGIEIGNYEVSDADADSTYLQFSVKYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KE74</accession>
    <name>B1KE74_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323407.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85060">
        <property type="protein sequence ID" value="ACA85060"/>
        <property type="gene ID" value="Swoo_0765"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0765"/>
    <dbReference type="HOGENOM" id="CLU_2371223_0_0_6"/>
    <dbReference type="OrthoDB" id="1984541at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="95" mass="10741" checksum="C49E1DE838788B31" modified="2008-04-29" version="1">MNIKDEFCAEIRVAIGQCYELGYRPTRFEEMIAISHPVDVAKSFVISGDFQSGFKQLKKLGKLHLTVEGIMVTPKYATLFTKSELAAAKWRLDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES0</accession>
    <name>B1KES0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3826"/>
    <dbReference type="EnsemblBacteria" id="ACA88085">
        <property type="protein sequence ID" value="ACA88085"/>
        <property type="gene ID" value="Swoo_3826"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3826"/>
    <dbReference type="eggNOG" id="COG2968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080344_3_0_6"/>
    <dbReference type="OMA" id="LPNGPHI"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="256" mass="28406" checksum="E20E043CB310D8EA" modified="2008-04-29" version="1" precursor="true">MQAKAVKHMIKYDYFGVPMKRSLLSNLLTSTFLSASILAAPLLQASEISFPHLETVGVSKLAVEADMAEINVQVAIKDKTAKGAKTLSDTAVAKFIERLKATGVERADIQSANLNLQPQYHYQKDKPAELVGYNASRQITVKVRELARLNNILDSALEEGINRINNIALKTSKEADYVEKARQAAIVDAKNKARSLAKGFGEKLDGVWEIRYFEQHPVQPVMLRMNAASPKFDAAESYQQGQVTITDRVEVVFKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEU6</accession>
    <name>B1KEU6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323444.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0802"/>
    <dbReference type="EnsemblBacteria" id="ACA85097">
        <property type="protein sequence ID" value="ACA85097"/>
        <property type="gene ID" value="Swoo_0802"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0802"/>
    <dbReference type="eggNOG" id="COG3596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_997287_0_0_6"/>
    <dbReference type="OMA" id="PRMYWGT"/>
    <dbReference type="OrthoDB" id="1441216at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="296" mass="33677" checksum="910A0B523A7A5B1A" modified="2008-04-29" version="1">MLDAICTLDKSQDEPYSVFKFQKLSRDEIEEYRQFLLCPVCRQKAFYRKASKDGKAACFGSRYHKLDCSEFKPSQAKLREEQDALEVNQQLVNSDALVIDFSKPATVKTAGDKQRAKSKKASSSKSTPPEKLACDVDEVAGSELSEGDPVIPQKRVATQGLEKLLNSLLRGSDLADSDLWVYTDEKYRWRAKNLFVNFADAEPTENGAPRMYWGTISHSDKSMTWLNPADCQDVGIPIDEFQKALFHQFAIKERRDIEGAGIIMFGKCFWNKGKTRKIIQLWGKDTKRMFISKSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEW4</accession>
    <name>B1KEW4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_0820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323462.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85115">
        <property type="protein sequence ID" value="ACA85115"/>
        <property type="gene ID" value="Swoo_0820"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0820"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_87_0_6"/>
    <dbReference type="OMA" id="AHRHDDH"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="159"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="261" mass="29501" checksum="F2882675B147AFD9" modified="2008-04-29" version="1">MSDKSPNFPAFDSDSYPQKVVSLRATGGDHEAETPFHQHHKCQLVLALNGYVKCKIADAIWMVPAYCAAWIPSQVPHSNRISSNADVRMLFVDPEISGMPDRSCTLSISPLLRELIVHLTEQDQHYLDGSATARLVEVLIEQLRDMPTEHFDFPTPIESRLSAIASQLMTTPDDRRSVGEWARQYAMSERTLARLTKQETGLTFGRWRGQLHIVLALQKLALGESVQRIAEDLGYESVSAFITFFKKTLDKPPKQYMKLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF30</accession>
    <name>B1KF30_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323528.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0887"/>
    <dbReference type="EnsemblBacteria" id="ACA85181">
        <property type="protein sequence ID" value="ACA85181"/>
        <property type="gene ID" value="Swoo_0887"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0887"/>
    <dbReference type="eggNOG" id="ENOG502Z7NT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047951_0_0_6"/>
    <dbReference type="OMA" id="ARYKITM"/>
    <dbReference type="OrthoDB" id="325408at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="461" mass="53725" checksum="257321E4D77087EA" modified="2008-04-29" version="1">MSKVRVKQEESLSIKFIHQMKVGDNRRLDLYFFLPKEMGIGPHSLNEEEYYHSAITGRRSYYSTGLHLPLVQSRFASQKKRTVEEFRLYLNLFAYQFAVAIETDSKELRQIEEPEEFFTALRDLSELVAQLLKKFRRNEPSDPKRKPYFENADNYLSWFCEQQLLKLLSRAPRGSEYSEMIETVVTQCRAERQHRDARRYNSQQTQDDPNRISNKMLLLRRLIQQGVVLKDELKTLGTGLKKMTTGFATAMVMLVVSALIIKAQGVFSGLTIALVLTLAVIYGFREIFKEDIRNALWRFIQKGRPKWSRILRDTTSQTAIAKQLVWLDFMKTSELPDPITDILKRRHSQNKLDAEVLHYGIHTRVTQKEFLTGYTSIQEQVNFSLVPFARYLERGKAKIYKESDGKISNDSVERRYQINMILALKNGKGETEYARYKVTMNRSTIIDISQSDIPEGIPLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFD1</accession>
    <name>B1KFD1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Swoo_2393</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325014.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2393"/>
    <dbReference type="EnsemblBacteria" id="ACA86672">
        <property type="protein sequence ID" value="ACA86672"/>
        <property type="gene ID" value="Swoo_2393"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2393"/>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030140_0_2_6"/>
    <dbReference type="OMA" id="NRMLDNC"/>
    <dbReference type="OrthoDB" id="944149at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="212"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACA86672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="336" mass="36490" checksum="E38F02146436727A" modified="2008-04-29" version="1">MTIRVAINGYGRIGRNVLRALYESEKDYPIQIVALNDLGDASINAHLTKYDSVHGRFNAKVDHDAEAIYVNDDKILTFSERDPAKLPWAELNVDVVFECTGIFTSKEAVQPHLTAGAKKVLISAPGKNVDATVVYGVNNNEITADMTVISNASCTTNCLAPFAKPLNDEIGIESGLMTTIHAYTNDQRLSDVYHTDLRRARAAAMSMIPTKTGAAAAVGLVVPELAGKFDGLAVRVPTVNVSLVDLSFIAARDTTVEEVNAIIESAASLSPMNEVLAVNKEPLVSIDFNHNPFSSNFDATQTRVNGRLVKVMAWYDNEWGFSNRMLDNAVALMTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE3</accession>
    <name>B1KFE3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326448.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3860"/>
    <dbReference type="EnsemblBacteria" id="ACA88118">
        <property type="protein sequence ID" value="ACA88118"/>
        <property type="gene ID" value="Swoo_3860"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3860"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_4_5_6"/>
    <dbReference type="OMA" id="PTHQITA"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="162" mass="18084" checksum="99F46E680907A5C2" modified="2008-04-29" version="1">MKIREFEFADFKAVTDIYQEGIDGGNATFEKQPKAWPEWDRAMLAPCRLVIEIDSQLVGWAGLLPTSTREAYAGVVEVSIYISDNAKGNGAGYALLTELIKQSEEAGCWTLQSAIFPENQASINLHQKCGFKILGVRERLGQMNGVWRDVVLMERRSDKVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFI0</accession>
    <name>B1KFI0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326485.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3897"/>
    <dbReference type="EnsemblBacteria" id="ACA88155">
        <property type="protein sequence ID" value="ACA88155"/>
        <property type="gene ID" value="Swoo_3897"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3897"/>
    <dbReference type="HOGENOM" id="CLU_1804889_0_0_6"/>
    <dbReference type="OMA" id="ELTESKW"/>
    <dbReference type="OrthoDB" id="2125336at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="143" mass="16365" checksum="E38DD971346BCE13" modified="2008-04-29" version="1">MQSGKAITLKYLYDHIEDSVLIFSCEKCSVYLVADEKQYADSLVKLEFKGVQCVRSVRTDCSPVVGIYPKEFGVSYFVELTESKWPVEAHQLYVYADASIEPRGRHFVVSNHDIFHEILAESFTETIIQPDDNEYDVVKSQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFM7</accession>
    <name>B1KFM7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RES domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0899</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MbcT/ParT/Res family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323540.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85193">
        <property type="protein sequence ID" value="ACA85193"/>
        <property type="gene ID" value="Swoo_0899"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0899"/>
    <dbReference type="eggNOG" id="ENOG5032TMW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_696174_0_0_6"/>
    <dbReference type="OrthoDB" id="1536679at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014914">
        <property type="entry name" value="RES_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08808">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RES" evidence="2">
        <location>
            <begin position="152"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="396" mass="45765" checksum="E8FC0CF7CDB1CFF1" modified="2008-04-29" version="1">MYNMQKPYSIEELKEKIETYQGYADYFSDPVFSTHKEWNGVDFHLFVKNALEDAKEYISDKGLNLGHKGAPLGRVSDILNSYEQYSEVVMLGLKGKRSSAYKVFDKNIAPKLTFAFKTFRNMPGDPRFDRESISHGYRIRTGEDSYNANYSRKDLFHIPFELNHLIGNNRFSLSGFPCLYMANSVYGAWEELNRPNIDKCFVSKFDLTKLSFIDLSMVPSEITSRLKNHITFLKKQTKPLPAEYVETFEHLLVDYLYIWPAILCCSFKVKNDSTFKPEYIFPQLFLEWLVSTEYSLYDGIRFLSTKSLALDSHIDINAQSLAKNYVIPARQYNSSGFCSEYVNKIMLTEPVNYAFHTLFGNKGKEKSSESESKYTDTVFGELEEILADKELCKVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFR1</accession>
    <name>B1KFR1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0934"/>
    <dbReference type="EnsemblBacteria" id="ACA85227">
        <property type="protein sequence ID" value="ACA85227"/>
        <property type="gene ID" value="Swoo_0934"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0934"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_3_2_6"/>
    <dbReference type="OMA" id="AHRMTKS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="18597" checksum="78F7B1CB74530757" modified="2008-04-29" version="1">MHCAQSNELQGYMSIDQKCNPLSLDNQVCFSLYSATNAMVRAYRPLLNELDLTYPQYLAMLVLWDNEGISVKTLGEQLHLDSGTLTPLLKRLETKGLVSRGRSEVDERVRVLHITEKGRELKQFAAKVPEKMRCKLNIKPEVFSELKSLCDQAYMSLTQAEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFR3</accession>
    <name>B1KFR3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transporter, chromate ion transporter (CHR) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0936</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323576.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0936"/>
    <dbReference type="EnsemblBacteria" id="ACA85229">
        <property type="protein sequence ID" value="ACA85229"/>
        <property type="gene ID" value="Swoo_0936"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0936"/>
    <dbReference type="eggNOG" id="COG2059">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018106_0_1_6"/>
    <dbReference type="OMA" id="GMYKNFC"/>
    <dbReference type="OrthoDB" id="1884249at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA85229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="386" mass="41413" checksum="B3A3CAD62DAFA1BC" modified="2008-04-29" version="1">MLQIFIRFFSLGLISFGGPAAHIGYFRQTFVQELGWLDDKRYGSLVALSQFMPGPGSSQVGFAIGYHRGGLLGGLAAFVGFTLPSFILLFLFAVTSSQLMNYPITLGVIHGLKLLAVVVVVDAVWIMFKQFCQRRIAILLMLTSFAVISLFPGIWIQFALLMLAAVVGRQWLSSTDTSGEPKQSIKLNYLWLSLFALLFIGSSIMLFGGLSSQESGLLGLFSQFYQVGSLVFGGGHVVLPLLQSSVGDAISGDQFLTGYALAQAVPGPMFVLAAYLGAEIWVAQPLLGALVATLAIFLPGFLLMLVALKSWHAMSGRPKITGAIAGVNACVVGFLLAALYDPIFTSAVKDNLDMVLVVVGFGLFKLLKPNIFYLVLSFAILGAVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG91</accession>
    <name>B1KG91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326558.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3971"/>
    <dbReference type="EnsemblBacteria" id="ACA88228">
        <property type="protein sequence ID" value="ACA88228"/>
        <property type="gene ID" value="Swoo_3971"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3971"/>
    <dbReference type="HOGENOM" id="CLU_1936687_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="130" mass="14806" checksum="F7E573EE9A64B45C" modified="2008-04-29" version="1">MTMYQKFKEYEALQKGILKEILSELGAESLESVDEDELWEFDQHLKSGWNITPHGEHLSCLINATIRVEIPLYVSGCVGIDAGHFVEYLVSNNINGYDYQLITKELESLGINEKATKINPELTSDVWKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE1</accession>
    <name>B1KGE1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4022"/>
    <dbReference type="EnsemblBacteria" id="ACA88278">
        <property type="protein sequence ID" value="ACA88278"/>
        <property type="gene ID" value="Swoo_4022"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4022"/>
    <dbReference type="eggNOG" id="COG1672">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_329795_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="854" mass="99350" checksum="9974CABFCC1AF9CA" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGQ8</accession>
    <name>B1KGQ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325118.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2500"/>
    <dbReference type="EnsemblBacteria" id="ACA86777">
        <property type="protein sequence ID" value="ACA86777"/>
        <property type="gene ID" value="Swoo_2500"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2500"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_1_6"/>
    <dbReference type="OMA" id="DEHKHIV"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="220" mass="25113" checksum="C4D2765D4B37DC89" modified="2008-04-29" version="1">MTFFDETAVTAADKTFFQLRKDIVEGVVLAGSKLSETELSTKYSVSRAIIREAINRLESCNLVERKANVGARVVALTPEGLIELYQVRESLEGMAARLAAKNMTSQEIDDLNALLNTHFQKVKTGESYYQEAGDVDFHYRIILGSKNRHLITMLIDGIYHLVRMYRVQLGMSGPRITTAFDEHRHIVQAISNRDEELAEMLMRRHIMYSQRNVETKLEQS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH27</accession>
    <name>COBS_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="1">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cobS</name>
        <name type="ordered locus">Swoo_4083</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CobS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326668.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KH27"/>
    <dbReference type="STRING" id="392500.Swoo_4083"/>
    <dbReference type="EnsemblBacteria" id="ACA88339">
        <property type="protein sequence ID" value="ACA88339"/>
        <property type="gene ID" value="Swoo_4083"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4083"/>
    <dbReference type="eggNOG" id="COG0368">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057426_1_1_6"/>
    <dbReference type="OMA" id="GHTGDTY"/>
    <dbReference type="OrthoDB" id="1996371at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000189619" description="Adenosylcobinamide-GDP ribazoletransferase">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <sequence length="257" mass="27770" checksum="8B90686D042F9A1A" modified="2008-04-29" version="1">MHVLRQQLTLFFIAMGFFTRIPMPTWVKVDGESLNKANRYFGLIGLLVGGICALVYEITRGFLPVSVSIIFAMIAGLVVTGGFHEDGLADTADGLGGGWSVADKLKIMKDSRIGTYGALALVMGLMLKFILLSELALYNPDLVVTALIVGHTLSRVMAASLIFSQSYVRDDDSSKSKPLAQNQTVNELLILLATAVLVLWCSGLSGGLYIAIGLVLLRWGLIYLFHRQIGGYTGDTLGATQQLAELACYLMLLGFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHB0</accession>
    <name>B1KHB0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323764.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA85418">
        <property type="protein sequence ID" value="ACA85418"/>
        <property type="gene ID" value="Swoo_1125"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1125"/>
    <dbReference type="HOGENOM" id="CLU_031876_0_0_6"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766606" evidence="1">
        <location>
            <begin position="30"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="445" mass="49750" checksum="11E7F0EA3F19F518" modified="2008-04-29" version="1" precursor="true">MRLNQVLSLSFLGCTLLTGSFLSIPTVSAASDLKASPSGAVMRGKGPSGISYCDLARGTNVDGGYCQILWSDLQRARFSQKEYDALTTTAEKDTYLDSKFQFELIDEALAAAKAFNDQHDRGDADKFKVLLRIRAGVDSPDWVRNRTKEVDWYFKSFADTQKHKLPAFWTEKYQDSYLSLMRGLAAKYDNNELIGAVAASMCMTVHSEIMWNRTGRKKDADGNEIRNADGKNPRQVNIAAMTDASVLGSDVYTNPKDYACLERQVDIHKNTWKRTPSIFGSHLYQKYYLTEKDANHAADEQGKKRSKIDAGDATTVVNKTHDIFSYCREKLGDRCILGNNSLRDDEVAINENIYDLLSTYGPPLYFQTNVFGSLEDKEPKDAFSYEQMLAAMDLAGSTFGALMVEMAMGWDCDNEYDKTDCTKADVHSEAPNFKAPRDVLKANGS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHG5</accession>
    <name>RUVC_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="1">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ruvC</name>
        <name type="ordered locus">Swoo_2573</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RuvC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325190.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KHG5"/>
    <dbReference type="SMR" id="B1KHG5"/>
    <dbReference type="STRING" id="392500.Swoo_2573"/>
    <dbReference type="EnsemblBacteria" id="ACA86850">
        <property type="protein sequence ID" value="ACA86850"/>
        <property type="gene ID" value="Swoo_2573"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2573"/>
    <dbReference type="eggNOG" id="COG0817">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091257_2_1_6"/>
    <dbReference type="OMA" id="AICHIWR"/>
    <dbReference type="OrthoDB" id="1815080at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000090563" description="Crossover junction endodeoxyribonuclease RuvC">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <sequence length="173" mass="18530" checksum="C7966C8DAB5D6668" modified="2008-04-29" version="1">MAIILGIDPGSRITGYGVIQCNGRSQIYLGSGCIRTASDDFPYRLKQIFDGVSEIIRQYQPNFFAIERVFLAKNADSALKLGQARGAAIVAATNADLPVAEYSATQIKSAVVGTGKAEKTQVQHMVQQILKLPAAPQADAADALGVAICHFHTSQSLVSLGGRANTRTYGRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHG6</accession>
    <name>B1KHG6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein Swoo_2574</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2574</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325191.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2574"/>
    <dbReference type="EnsemblBacteria" id="ACA86851">
        <property type="protein sequence ID" value="ACA86851"/>
        <property type="gene ID" value="Swoo_2574"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2574"/>
    <dbReference type="eggNOG" id="COG0217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062974_2_2_6"/>
    <dbReference type="OMA" id="ETIMYEG"/>
    <dbReference type="OrthoDB" id="1304328at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="248" mass="26716" checksum="7CC94DEE16B00DF6" modified="2008-04-29" version="1">MAGHSKWANIKHRKAAQDAKRGKLFTKFIRELTVAAREGGSDADANPRLRAAIDKALSNNMTRDTVERAIKRGAGELDGQVLETIMYEGYGPGGTAVMVETMTDNKNRTVSGVRNAFSKSGGNLGTDGSVSYLFDKRGVISYGEGIDEDTIMDAALEAGADDVVTHDDGSIDVFTTPEDFGGVKDALDSAGFESVNAEVTMIPSTKADLDASTAPKFMRLIDNLEDHDDVQEVYHNAEISDEIMESLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHH6</accession>
    <name>B1KHH6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325201.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2584"/>
    <dbReference type="EnsemblBacteria" id="ACA86861">
        <property type="protein sequence ID" value="ACA86861"/>
        <property type="gene ID" value="Swoo_2584"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2584"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_35_2_6"/>
    <dbReference type="OMA" id="LTAFMPQ"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="299" mass="33658" checksum="805C861B980ADD21" modified="2008-04-29" version="1">MDRAKSTLEQWRILQAVVDHSGYSQAAKQLNKSQSSLNHAVAKLQDQLGVQLLEVKGRKAYLTAQGEVLLRRSRHITNSVNELEQLANNLEKGWEPNLTIAREIIYPMPTLVNALKRFQPDSRGTRVTILDSVINGTQELIRDGEVDIAICGGVPPKGFIAEPLCHINFLLVCHPNHPLCSETVIEDDLILAQHLQIVIKDTGQSISTEAGWLKAEQRWTVSNFHEAIEILEQNIGFCWVPEYLVCNLIQAGRLKKLRLKGNTHKKALLHLVIPNRDLQGPASEHLESLILREHKKDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ0</accession>
    <name>B1KHJ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2598</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325215.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2598"/>
    <dbReference type="EnsemblBacteria" id="ACA86875">
        <property type="protein sequence ID" value="ACA86875"/>
        <property type="gene ID" value="Swoo_2598"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2598"/>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031614_0_0_6"/>
    <dbReference type="OMA" id="IFERLAW"/>
    <dbReference type="OrthoDB" id="470322at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="575" mass="64020" checksum="E7DF8BA10774CE19" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KHJ2</accession>
    <name>B1KHJ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylated-DNA-(Protein)-cysteine S-methyltransferase DNA binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325217.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2600"/>
    <dbReference type="EnsemblBacteria" id="ACA86877">
        <property type="protein sequence ID" value="ACA86877"/>
        <property type="gene ID" value="Swoo_2600"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2600"/>
    <dbReference type="eggNOG" id="COG3695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_5_6"/>
    <dbReference type="OMA" id="PRHSRHV"/>
    <dbReference type="OrthoDB" id="1928537at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="1">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="117" mass="13389" checksum="AC946B0ED574253D" modified="2008-04-29" version="1">MSKQVTVSPIEKIWFIVNLIPKGYVCSYGKVADLAGLPGRARYVSTALKRAPKEMTLPWHRVVNSQGKISFESNTQAYQNQMERLRLDGVEVNRGKILLSQYEWKPDLATLMFEIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI66</accession>
    <name>B1KI66_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323890.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1252"/>
    <dbReference type="EnsemblBacteria" id="ACA85544">
        <property type="protein sequence ID" value="ACA85544"/>
        <property type="gene ID" value="Swoo_1252"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1252"/>
    <dbReference type="eggNOG" id="COG4137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049710_1_2_6"/>
    <dbReference type="OMA" id="MPGEFIT"/>
    <dbReference type="OrthoDB" id="955123at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="2">
        <location>
            <begin position="38"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="262" mass="28882" checksum="6A5952B5D39B6338" modified="2008-04-29" version="1">MVIFSASAMFFYCIALVLVVSRLFHSDGPNRRLVAAVAAIAVVLHAAALSQAMFTGDGQNFSLTNVISLVNWIIAFSFTVLLFRLKMIVVVPVVYACSIISVALLWLVPPEYITHFEIHPDILVHVVLSLMAYSALMIAALYAIQLAIIQNKLKSKKLIMNPAMPPLMTVEKQLYHLVIVGVILLSLSLATGFIFLDDMFEEGKGHKAVLSIIAWFTYIAMLAQQYWVGCKIRTAVIYTLSGATLLSLAYFGARIVKELILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KI90</accession>
    <name>B1KI90_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325281.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86941">
        <property type="protein sequence ID" value="ACA86941"/>
        <property type="gene ID" value="Swoo_2665"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2665"/>
    <dbReference type="HOGENOM" id="CLU_1668209_0_0_6"/>
    <dbReference type="OrthoDB" id="2093198at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767082" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="158" mass="17571" checksum="792DE1E427617D14" modified="2008-04-29" version="1" precursor="true">MKKSIMALLVATNMMLPAAVLAHEEPIEGQWCQNGNVVILGEFKLTPLHLARFGRFAEDECPSFGSEVGTKSCGQFDDEYGLTRAATDHLCNSIAYELRDDSREGDGGTVRPIFYGPESLKNSDKNHHEVYSIVQGVQFACGLCDMETERRERKLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KID9</accession>
    <name>B1KID9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_2714</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325327.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2714"/>
    <dbReference type="EnsemblBacteria" id="ACA86990">
        <property type="protein sequence ID" value="ACA86990"/>
        <property type="gene ID" value="Swoo_2714"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2714"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010756_1_0_6"/>
    <dbReference type="OMA" id="FKPNGKP"/>
    <dbReference type="OrthoDB" id="1034540at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="53"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="661"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA86990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1023" mass="112877" checksum="D18AABB47B22DEFB" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIE5</accession>
    <name>B1KIE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325333.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86996">
        <property type="protein sequence ID" value="ACA86996"/>
        <property type="gene ID" value="Swoo_2720"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2720"/>
    <dbReference type="eggNOG" id="COG1607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050164_2_1_6"/>
    <dbReference type="OMA" id="AFICATR"/>
    <dbReference type="OrthoDB" id="1712258at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="142" mass="15938" checksum="578B666C46CC6581" modified="2008-04-29" version="1">MPLTHPPETRSDAMNKRVQNSEARVIKAIFPSITNHHNTLFGGEALSWMDETAFIAATRFCRKPLVTVSSDRIDFKKAIPAGSLAEIIANVIHVGNTSLKVEVNIFVEDMYQDVREHAIRGVFTFVAVDENRKATKVWTDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIG3</accession>
    <name>B1KIG3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA/MotB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2738</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325350.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2738"/>
    <dbReference type="EnsemblBacteria" id="ACA87014">
        <property type="protein sequence ID" value="ACA87014"/>
        <property type="gene ID" value="Swoo_2738"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2738"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069369_1_0_6"/>
    <dbReference type="OMA" id="PMGETRN"/>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041544">
        <property type="entry name" value="MotY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18393">
        <property type="entry name" value="MotY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767373" evidence="3">
        <location>
            <begin position="20"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="172"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="32886" checksum="81A9919117526F32" modified="2008-04-29" version="1" precursor="true">MWLRVLLALTLFLPLTGSAELRHYVASLDQSEWKLSGNTPIMCRLEHDIPAYGKAVFTSTAGKDHNLNFSLDMWVKPDQVTQAKLMSLAPAWRPGVISKEITELTYQKYFSGEVPRNAAWSMLSELEQGMQPTFYYADWYNQSNKIAVGLSAVNFNRKYSEFKSCLASLLPYSFDDIAFTVLTYEFGGKELTRYAKAQIAKVQEYLSYDPEVELVLIDAYTDSYGGRSINQKISEERADSVKEFFISAGITQERIHTVGHGERHHVASNATIDERARNRRVVIRITKPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KII9</accession>
    <name>B1KII9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326812.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4229"/>
    <dbReference type="EnsemblBacteria" id="ACA88485">
        <property type="protein sequence ID" value="ACA88485"/>
        <property type="gene ID" value="Swoo_4229"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4229"/>
    <dbReference type="eggNOG" id="COG3113">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_13_4_6"/>
    <dbReference type="OMA" id="ICHLKGR"/>
    <dbReference type="OrthoDB" id="1864829at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="100" mass="11328" checksum="E1834BEA9D5E6F0C" modified="2008-04-29" version="1">MAEFTQQGSICHISGRLSQEEIPALWLRRKSLLNREVEVIDLSELSYSDSAGIAFILELMSVARAEKRSLSFTSASEQLSKLIDLYDLELFFNEEAKQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIL1</accession>
    <name>B1KIL1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326834.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4251"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88507">
        <property type="protein sequence ID" value="ACA88507"/>
        <property type="gene ID" value="Swoo_4251"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4251"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_0_1_6"/>
    <dbReference type="OMA" id="PLRMWTY"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="17"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="339" mass="37892" checksum="003A16701ED57CE6" modified="2008-04-29" version="1">MAQIKSINPSDGQICLSIIIPVYNEAEVLPPLIARLSRVLSSIPESAEIVFIDDGSCDNTWELLQQLPVNSCEHQCIRLSRNFGKEAAMTAGLEQARGLAVILLDADLQDPPELIPQMLEAWRSGFDVVNMKRKKRLGESWFKRFSAAAFYRIINGMAESPVPENVGDFRLLSRQVVDCINSLPERNRFMKGILSWPGFSQTEILFDRDPRYLGETKWNYSKLVGLAMDGITSFSIKPLRLATWAGILTALSAFTYGGWVLLKTMLWGETVVGYPSLMIVQVALAGVQLLALGLIGEYLGRVFMEVKQRPIYLISEVEHKGSRSQNEAGDKVRYLESMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIP4</accession>
    <name>B1KIP4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4285</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4285"/>
    <dbReference type="EnsemblBacteria" id="ACA88540">
        <property type="protein sequence ID" value="ACA88540"/>
        <property type="gene ID" value="Swoo_4285"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4285"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_6"/>
    <dbReference type="OMA" id="TRIERMV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="295" mass="33694" checksum="2063FF250BF10F41" modified="2008-04-29" version="1">MSLPEFKMTQLRHFIWVAELKGFHAAAKKACRTQPAISLSIRELENKLDTALFEKENTKSTILTPFGKYFLPKAKELIFHHDNLALDMELMCEHKTGHLRLASVPSISSRMLPDLLSKFINDVPELQISLYDDNSEAVLKKIEKQQVDIGISSLPYKNEHTDIRFTPIWKDQLGVVCHKNNPLVKKTELHWRELRKLQLIRNGTSRLLEDTEAKPLLNDSQLFISTMISLIAMLEAGLGITTLPWFAFPENNKKLRFIPLKTPTVMRQTGIVQLKNKSLSPAASALKNFIIKNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KIX0</accession>
    <name>B1KIX0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Swoo_1326</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323964.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1326"/>
    <dbReference type="EnsemblBacteria" id="ACA85618">
        <property type="protein sequence ID" value="ACA85618"/>
        <property type="gene ID" value="Swoo_1326"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1326"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027579_2_1_6"/>
    <dbReference type="OMA" id="HIPWCVR"/>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACA85618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="378" mass="42995" checksum="E30C997B783AD941" modified="2008-04-29" version="1">MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQNGELPQQEYVDALISDLAHDLQYVQGRKLHSIFIGGGTPSLFHASQIEKLLTHVSQVIPFQDDIEITMEANPGTLEHDDFEAYYQAGVTRLSIGVQSFSSDKLNLLGRIHDEDEAKVAAQKALSAGYKSFNLDLMHGLPNQSFAEAMADIDTAAALSPPHLSWYQLTIEQNTLFHSRPPQLPDDEALWEIYEQGQKKLAALGYQQYEISAYAKPGFQCRHNINYWQFGDYLGIGCGAHGKITILNENKIIRTVKIKHPKGYLATDSYNFETTEVAKEDRALEYLMNRFRLMSPIPKREFEQRTGLSREVLTSGIQRAKEKQLLTENDEYWELTSRGKLFVNELLSQFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ20</accession>
    <name>B1KJ20_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325376.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87040">
        <property type="protein sequence ID" value="ACA87040"/>
        <property type="gene ID" value="Swoo_2764"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2764"/>
    <dbReference type="eggNOG" id="ENOG5032I9A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_186874_0_0_6"/>
    <dbReference type="OMA" id="VGAKPRY"/>
    <dbReference type="OrthoDB" id="2092096at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021677">
        <property type="entry name" value="DUF2986"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11661">
        <property type="entry name" value="DUF2986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="76" mass="8443" checksum="09BCBF4A436FC79E" modified="2008-04-29" version="1">MNKKQKMIKLTAKRAKARKNKHTAPTIKKYVSKGDRAKALAQEQAEAALSGKQTAEEVQSTTEAEQEQQTDTPETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ21</accession>
    <name>B1KJ21_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325377.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2765"/>
    <dbReference type="EnsemblBacteria" id="ACA87041">
        <property type="protein sequence ID" value="ACA87041"/>
        <property type="gene ID" value="Swoo_2765"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2765"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_0_1_6"/>
    <dbReference type="OMA" id="GPIIGQN"/>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="503" mass="52756" checksum="81440F75041938BF" modified="2008-04-29" version="1">MTTAKFVQGSIMRHILVMSSTSAVGISALFVVDLIDIFFLSLLGEQELAAAVGYAGTISFFTTSIGIGLSIALGALVSRAIGAKQMEAAKRLLLNCAVVTLLMSLLVSAVVTYFIPELLSLVGATGHTAELAAGYLYILVPSLPLICLAMALGAALRAVGDAKLSMMSTLGGGGINLVFDPIFIFALGMGIEGAAVASVLARAGVLFIAARGVIVKHKLFGQFDFGSFKTDLSAIFAIAAPAMLTNIATPIGNAVVTRAIADFGDGYVAGWAVLGRLVPVCFGMIFALSGAVGPIVGQNYGAHEFDRVRESLTKALQFCAMYVVGVSLILMLLQDQIISVFDMQGDSAEIIRFFCTYIAVFFVFSGALFVANASFNNLGKAKYSTFFNVGKATIGTIPFVYFGAQWGGVYGVLVGQVIGAIIFAILGVYTAFRLVDKVRADASKELASTVSDEQDEFDTELSPSSTNALSSSCALMAQITEEQDAEAGSEVREFIKPTGDKAS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2015-03-04" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ76</accession>
    <name>T3HPD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trans-3-hydroxy-L-proline dehydratase</fullName>
            <shortName>T3LHyp dehydratase</shortName>
            <shortName evidence="3">t3HypD</shortName>
            <ecNumber evidence="2">4.2.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Trans-L-3-hydroxyproline dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_2821</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2014" name="Elife" volume="3" first="E03275" last="E03275">
            <title>Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks.</title>
            <authorList>
                <person name="Zhao S."/>
                <person name="Sakai A."/>
                <person name="Zhang X."/>
                <person name="Vetting M.W."/>
                <person name="Kumar R."/>
                <person name="Hillerich B."/>
                <person name="San Francisco B."/>
                <person name="Solbiati J."/>
                <person name="Steves A."/>
                <person name="Brown S."/>
                <person name="Akiva E."/>
                <person name="Barber A."/>
                <person name="Seidel R.D."/>
                <person name="Babbitt P.C."/>
                <person name="Almo S.C."/>
                <person name="Gerlt J.A."/>
                <person name="Jacobson M.P."/>
            </authorList>
            <dbReference type="PubMed" id="24980702"/>
            <dbReference type="DOI" id="10.7554/eLife.03275"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>BIOPHYSICOCHEMICAL PROPERTIES</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C) in vitro. Displays no proline racemase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10320"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:39785"/>
            <dbReference type="ChEBI" id="CHEBI:57938"/>
            <dbReference type="EC" id="4.2.1.77"/>
        </reaction>
    </comment>
    <comment type="biophysicochemical properties">
        <kinetics>
            <KM evidence="2">6.7 mM for trans-3-hydroxy-L-proline</KM>
            <text evidence="2">kcat is 4.1 sec(-1) for t3LHyp dehydration.</text>
        </kinetics>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the proline racemase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.77" evidence="2"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325432.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KJ76"/>
    <dbReference type="SMR" id="B1KJ76"/>
    <dbReference type="STRING" id="392500.Swoo_2821"/>
    <dbReference type="EnsemblBacteria" id="ACA87096">
        <property type="protein sequence ID" value="ACA87096"/>
        <property type="gene ID" value="Swoo_2821"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2821"/>
    <dbReference type="eggNOG" id="COG3938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036729_0_0_6"/>
    <dbReference type="OMA" id="ERRAYCM"/>
    <dbReference type="OrthoDB" id="559014at2"/>
    <dbReference type="SABIO-RK" id="B1KJ76"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050346">
        <property type="term" value="F:trans-L-3-hydroxyproline dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="PTHR33442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000432262" description="Trans-3-hydroxy-L-proline dehydratase">
        <location>
            <begin position="1"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="102"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="267"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q4KGU2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="24980702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="3">
        <source>
            <dbReference type="PubMed" id="24980702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <evidence type="ECO:0000312" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87096.1"/>
        </source>
    </evidence>
    <sequence length="346" mass="37985" checksum="5551570BFBA9332E" modified="2008-04-29" version="1">MKLNKLPLEVVGNRQQFITLDAHTEGEPLRIIISGYPEILGETILEMKEYVAQHLDRYRTLLMHEPRGHADMYGALITRPVSKEADFGVLFLHNEGYSSMCGHGILALVKVMCETNTILLGCEPRVIKIDAPAGLITATASLDEEGRVQASFENVDSWAEAINCSVMVEGLGEVNYDIGFGGAYYAYIDADALGLSCGRENVAQLIDLGRRIKHAVMDSHPLVHPLESDLSFLYGTIFISKEVTEKAAHSRHVCIFADGEVDRSPTGTGVAARAALLYAKGEIGLNQPLVIESIVDGKMTVSALREQDFHGKKAIIPQVSGRSYITGQHQFIVDPDDQFQDGFILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJ91</accession>
    <name>B1KJ91_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325447.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2836"/>
    <dbReference type="EnsemblBacteria" id="ACA87111">
        <property type="protein sequence ID" value="ACA87111"/>
        <property type="gene ID" value="Swoo_2836"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2836"/>
    <dbReference type="eggNOG" id="COG1574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_6_1_6"/>
    <dbReference type="OMA" id="MEGAMWD"/>
    <dbReference type="OrthoDB" id="751534at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="95"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="597" mass="66956" checksum="02DD3265F2ED8EB7" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJC3</accession>
    <name>B1KJC3_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable chemoreceptor glutamine deamidase CheD</fullName>
            <ecNumber evidence="3">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheD</name>
        <name evidence="4" type="ordered locus">Swoo_4342</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CheD family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.44" evidence="3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326921.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4342"/>
    <dbReference type="EnsemblBacteria" id="ACA88595">
        <property type="protein sequence ID" value="ACA88595"/>
        <property type="gene ID" value="Swoo_4342"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4342"/>
    <dbReference type="eggNOG" id="COG1871">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087854_0_0_6"/>
    <dbReference type="OMA" id="MQAKIFG"/>
    <dbReference type="OrthoDB" id="1863047at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16352">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01440">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038592">
        <property type="entry name" value="CheD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005659">
        <property type="entry name" value="Chemorcpt_Glu_NH3ase_CheD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35147">
        <property type="entry name" value="PTHR35147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03975">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="209" mass="23691" checksum="06B45A2419012B9F" modified="2008-04-29" version="1">MTALVIPTSTKGFEEIPRKWDNKHNKIVARVDPGAFYITAHDEYVFTRLGSCVAACIWDPLLGIGGLNHFLLPERELNEDWHELMSFSCRYGNFAMEQLINGILALGGQKQRLRAKVFGGAQMGKETVLNVGRSNIDFVKNYLHMEGIEVESEDLGGGWPRKVLFHPNSGKVLLKRLPVSGIVEMEREERVYLKDIVKEQTESKVELFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJF4</accession>
    <name>B1KJF4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ig family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_4374</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326952.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4374"/>
    <dbReference type="EnsemblBacteria" id="ACA88626">
        <property type="protein sequence ID" value="ACA88626"/>
        <property type="gene ID" value="Swoo_4374"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4374"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_378937_0_0_6"/>
    <dbReference type="OrthoDB" id="410450at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764962" evidence="2">
        <location>
            <begin position="18"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="CADG" evidence="3">
        <location>
            <begin position="39"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="CADG" evidence="3">
        <location>
            <begin position="131"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA88626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="731" mass="76865" checksum="03D5EA8948EFB74B" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJQ2</accession>
    <name>B1KJQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc carboxypeptidase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1433</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324071.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1433"/>
    <dbReference type="EnsemblBacteria" id="ACA85725">
        <property type="protein sequence ID" value="ACA85725"/>
        <property type="gene ID" value="Swoo_1433"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1433"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079078_0_0_6"/>
    <dbReference type="OMA" id="WNIPDGF"/>
    <dbReference type="OrthoDB" id="397741at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA85725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="320" mass="35359" checksum="6B546ADE95CC3E95" modified="2008-04-29" version="1">MSQSDVYSIGKIGQKWGAEERLAWRNLQSVKRSYQDDVVSNILPLKAHFEVEQYGALSYDVEKYPLFVVKSRDWDSNKPTVLVSGGVHGYETSGVHGALRFLETKALGYSDKFNLVVAPCVSPWGYETINRWNPNAVDPNRSFYTDSPAEESAGLMAMVASLGQSLDKSLDESSAQRLMAHIDLHETTDTDNSEFRPALAARDAVVHDNWNIPDGFYLVGDSENPVDEFQTAIIKAVEKVTHIAPPDEDGKLIGVPFSQKGVINYATKALSLCTGFSDARYNTTTEVYPDSPHSNDENCILAQVEAITSGLDFIIQDRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJT9</accession>
    <name>B1KJT9_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GyrI-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325462.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2851"/>
    <dbReference type="EnsemblBacteria" id="ACA87126">
        <property type="protein sequence ID" value="ACA87126"/>
        <property type="gene ID" value="Swoo_2851"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2851"/>
    <dbReference type="eggNOG" id="COG4832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083625_0_0_6"/>
    <dbReference type="OMA" id="GKHHEIY"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008319">
        <property type="entry name" value="UCP031644"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031644">
        <property type="entry name" value="UCP031644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GyrI-like" evidence="1">
        <location>
            <begin position="20"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="210" mass="24555" checksum="453400DF88F92F61" modified="2008-04-29" version="1">MSDKYEWRKKEKSLYIPKNKPELLEVPSLNFITLSGEGSPEDEIFTQYIGTLYSLAYTIKMHPKTMTTKPNGYFDFTVYPLEGIWDINDQAKAHFLGTIDKKDLVYQLMIRQPKFVDTNLYEEMLNLAKSKRDNPLLEQVKFTTITDGRCIQMLHLGPFENESQTFEEMESFAQAQGLTRRSKVHREIYLSDPRKVAPEKLKTVLRFQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJW6</accession>
    <name>B1KJW6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325489.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2878"/>
    <dbReference type="EnsemblBacteria" id="ACA87153">
        <property type="protein sequence ID" value="ACA87153"/>
        <property type="gene ID" value="Swoo_2878"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2878"/>
    <dbReference type="eggNOG" id="ENOG502ZPPW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_203836_0_0_6"/>
    <dbReference type="OMA" id="WFWFSCI"/>
    <dbReference type="OrthoDB" id="2097679at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010398">
        <property type="entry name" value="DUF997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06196">
        <property type="entry name" value="DUF997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="67" mass="7532" checksum="12CD5E8CB36838D1" modified="2008-04-29" version="1">MFSLSKTALILTAVYFVLWCAGPVLIDETWLWFGMPVWFWFSCIVAPVALISSLIFLVGFLQGNADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJX2</accession>
    <name>B1KJX2_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pyruvate formate-lyase-activating enzyme</fullName>
            <ecNumber evidence="12">1.97.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_2884</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:19225"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12190"/>
            <dbReference type="Rhea" id="RHEA-COMP:12191"/>
            <dbReference type="Rhea" id="RHEA-COMP:14480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29947"/>
            <dbReference type="ChEBI" id="CHEBI:32722"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:140311"/>
            <dbReference type="EC" id="1.97.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.4" evidence="12"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325495.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2884"/>
    <dbReference type="EnsemblBacteria" id="ACA87159">
        <property type="protein sequence ID" value="ACA87159"/>
        <property type="gene ID" value="Swoo_2884"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2884"/>
    <dbReference type="eggNOG" id="COG1180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058969_1_0_6"/>
    <dbReference type="OMA" id="IGVPNKR"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012838">
        <property type="entry name" value="PFL1_activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034465">
        <property type="entry name" value="Pyruvate_for-lyase_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00278">
        <property type="entry name" value="pyruvate_formate-lyase_activas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02493">
        <property type="entry name" value="PFLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="16"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA87159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="246" mass="27877" checksum="F5B533B028449A36" modified="2008-04-29" version="1">MAVTGRIHSLESFGTVDGPGIRFITFMQGCLMRCQYCHNRDTWDLHGGKDIEVEELMSQIISYRPFLESSGGGVTASGGEAILQAEFVSALFEACKKEGIHTCLDTNGFVRKYTPIIDELLDNTDLVLLDIKHIDDQRHIDLTKVSNHRTLQFAEHLHKRQQKTWIRYVVVGGYTDDIDSAKKLADFLKPMTNVEKVELLPYHELGKHKWEAMGEEYELNDISPPSGETMEQIKKVFVDAGLNAIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>B1KJZ7</accession>
    <name>B1KJZ7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325520.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2911"/>
    <dbReference type="EnsemblBacteria" id="ACA87184">
        <property type="protein sequence ID" value="ACA87184"/>
        <property type="gene ID" value="Swoo_2911"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2911"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067347_0_0_6"/>
    <dbReference type="OMA" id="CTWGGAT"/>
    <dbReference type="OrthoDB" id="1309717at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="8"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="287" mass="31468" checksum="4C46789AF0489C17" modified="2008-04-29" version="1">MTEETLLADLHSHTTASDGMLTPSELVERAIGNGVEMFAITDHDTTAGLAEAHAYNNSHATPLRLINGVEVSTRWHNHDIHIVALNIDPEDGEFDAFLINQRNLRELRAKEIGERLAKAGIEGAYEGAKSMAGDAALSRGHYARWLADKGYATSMANVFKKYLARGKTGYVPNNWSDMATAIEVIHKAGGIAVLAHPHGYKLSTKWVKRLVREFKESAGDAMEVVVSQQTVETRSQLIALSLQNELAASLGSDFHFPGSWTELGKSMYQPPGVNWVWQMDSWPAASA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KK45</accession>
    <name>RL31_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmE</name>
        <name type="ordered locus">Swoo_4424</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327002.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KK45"/>
    <dbReference type="SMR" id="B1KK45"/>
    <dbReference type="STRING" id="392500.Swoo_4424"/>
    <dbReference type="EnsemblBacteria" id="ACA88676">
        <property type="protein sequence ID" value="ACA88676"/>
        <property type="gene ID" value="Swoo_4424"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4424"/>
    <dbReference type="eggNOG" id="COG0254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114306_4_3_6"/>
    <dbReference type="OMA" id="WYPDAKV"/>
    <dbReference type="OrthoDB" id="2014569at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000126739" description="50S ribosomal protein L31">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <sequence length="70" mass="7497" checksum="141F68C45D24ECBC" modified="2008-04-29" version="1">MKPGIHPEYAEITATCTCGNVIKVNSTAGKSLHLDVCGACHPFYTGTQKIVDTGGRIDKFNKRFGALGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKC5</accession>
    <name>B1KKC5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1477</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324111.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1477"/>
    <dbReference type="EnsemblBacteria" id="ACA85765">
        <property type="protein sequence ID" value="ACA85765"/>
        <property type="gene ID" value="Swoo_1477"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1477"/>
    <dbReference type="eggNOG" id="ENOG502ZZN5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2083882_0_0_6"/>
    <dbReference type="OrthoDB" id="2165644at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="119" mass="12995" checksum="D61A032D8F53397B" modified="2008-04-29" version="1" precursor="true">MNLILKVVIVTILLIFTCDAFSSTRFRNVTITGAGVFLSGGKGILLININGDKSSMEECATTKRFAIDSNVPNYQEMVSLAMTAYISGQTNVDLYVTESCNSWGNAQDLRGIKMGTMPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKN0</accession>
    <name>B1KKN0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA topoisomerase 3</fullName>
            <ecNumber evidence="6">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA topoisomerase III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">topB</name>
        <name evidence="9" type="ordered locus">Swoo_2976</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds two Mg(2+) per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325583.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2976"/>
    <dbReference type="EnsemblBacteria" id="ACA87247">
        <property type="protein sequence ID" value="ACA87247"/>
        <property type="gene ID" value="Swoo_2976"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2976"/>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_5_2_6"/>
    <dbReference type="OMA" id="TYPRVDT"/>
    <dbReference type="OrthoDB" id="100725at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00953">
        <property type="entry name" value="Topoisom_3_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005738">
        <property type="entry name" value="TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PTHR11390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01056">
        <property type="entry name" value="topB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="6">
        <location>
            <begin position="194"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="640"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA87247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="666" mass="73774" checksum="6F238C409F1B1090" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KKQ0</accession>
    <name>B1KKQ0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="11" type="ordered locus">Swoo_2996</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325603.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2996"/>
    <dbReference type="EnsemblBacteria" id="ACA87267">
        <property type="protein sequence ID" value="ACA87267"/>
        <property type="gene ID" value="Swoo_2996"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2996"/>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013734_6_0_6"/>
    <dbReference type="OMA" id="HGFKRVC"/>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002766769" description="Probable cytosol aminopeptidase" evidence="9">
        <location>
            <begin position="29"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="CYTOSOL_AP" evidence="10">
        <location>
            <begin position="364"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="515" mass="54801" checksum="2A39DC36A4F3EB89" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL43</accession>
    <name>B1KL43_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0083</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322733.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0083"/>
    <dbReference type="EnsemblBacteria" id="ACA84384">
        <property type="protein sequence ID" value="ACA84384"/>
        <property type="gene ID" value="Swoo_0083"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0083"/>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1763">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010186_5_0_6"/>
    <dbReference type="OMA" id="APMPAGC"/>
    <dbReference type="OrthoDB" id="651103at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004435">
        <property type="entry name" value="MobB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012182">
        <property type="entry name" value="MobB_MoeA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03205">
        <property type="entry name" value="MobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036618">
        <property type="entry name" value="MobB_MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00176">
        <property type="entry name" value="mobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="375"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="601" mass="65173" checksum="29590CD5E41B2B88" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KL59</accession>
    <name>B1KL59_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322749.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0099"/>
    <dbReference type="EnsemblBacteria" id="ACA84400">
        <property type="protein sequence ID" value="ACA84400"/>
        <property type="gene ID" value="Swoo_0099"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0099"/>
    <dbReference type="eggNOG" id="ENOG5033EMF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_196839_0_0_6"/>
    <dbReference type="OMA" id="NCMNRRW"/>
    <dbReference type="OrthoDB" id="2075986at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA84400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="74" mass="8832" checksum="8E535141744845CC" modified="2008-04-29" version="1">MEKVIASFEFDGQVFRFRFGNENELESRKTANECYQFTPDDEDEQIDDFPTSCYNCMNRRWLIDGMACSKIERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE5</accession>
    <name>B1KLE5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-N-acetylglucosamine 2-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_1584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324216.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1584"/>
    <dbReference type="EnsemblBacteria" id="ACA85870">
        <property type="protein sequence ID" value="ACA85870"/>
        <property type="gene ID" value="Swoo_1584"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1584"/>
    <dbReference type="eggNOG" id="COG0381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061127_0_0_6"/>
    <dbReference type="OMA" id="VTYHPVT"/>
    <dbReference type="OrthoDB" id="1117971at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020004">
        <property type="entry name" value="UDP-GlcNAc_Epase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03568">
        <property type="entry name" value="NeuC_NnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="385" mass="42039" checksum="A0D4AF8E472EB865" modified="2008-04-29" version="1">MKILAITSIRSDYDLLSPLFFKLQQDTSFVLKLLVGGAHNSTSFGHTVNDIKNDGFDILMEIESLLDSNSSAGRLKSASILLISAIDVVKSFNPDLIIYAGDREEVMVGALLGGYLSIPTIHFYGGDHAADGHIDNPIRHAVSKLSTCHFVSTDEHVRRLLSLGEPPQRIFNIGSIALDKFNNVKPIPNIKDLIANKTVTKPAAILIYHPIDEEKRISTQLIDTMVESLNSAGYHCFLGLPNSDPGNAEIRSALKHAAKKYEDVTLYGNLSREQFVNLFKQSSLIVGNSSAGLLEAASIPVPCVNVGARQRDRYCTDNVLFVDATLKAIKQGIKQASSPEFTKKLAQISNPYGNGNSAKLAYSLIKENNFALIVGKTEDPLKNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLE8</accession>
    <name>B1KLE8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide biosynthesis protein CapD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1587"/>
    <dbReference type="EnsemblBacteria" id="ACA85873">
        <property type="protein sequence ID" value="ACA85873"/>
        <property type="gene ID" value="Swoo_1587"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1587"/>
    <dbReference type="eggNOG" id="COG1086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_684523_0_0_6"/>
    <dbReference type="OMA" id="KDPFTLM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysacc_synt_2" evidence="2">
        <location>
            <begin position="44"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="404" mass="46058" checksum="08D1F2665D920116" modified="2008-04-29" version="1">MHQTIGSTMTNTLKLIGREKELFTQDIGHYKAQLIDEVSQSRFLVLGGAGSIGQAVVKEIFKRVPLKLHVVDISENNLAELVRDIRSSFGYINGDFQTFALDIDSIEYDAFIAQDGQYDYVLNLSALKHVRSEKDPFTLMRMININIFNTDKTIEQSIASGVKKYFCVSTDKAANPVNMMGASKRIMEMFLMRRSEEMTISTARFANVAFSDGSLLHSFNQRMLKQQPIVAPTDIKRYFVTAQESGELCLMSCIFGENRDIFFPKLDEEQHLISFADIAVRYLSSRGYQAHICQSEDEARQLAATLPAKGIWPCYFTVSDTTGEKEVEEFFTAQETLDMARFSELGIIKNRLKYDPKLLELFVQEIESMKLAKSWSKEQVVQLFHLMLPEFGHKETGRSLDEKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLI8</accession>
    <name>B1KLI8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1627</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FliO/MopB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324259.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1627"/>
    <dbReference type="EnsemblBacteria" id="ACA85913">
        <property type="protein sequence ID" value="ACA85913"/>
        <property type="gene ID" value="Swoo_1627"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1627"/>
    <dbReference type="eggNOG" id="COG3190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113213_3_0_6"/>
    <dbReference type="OMA" id="KRMQVPA"/>
    <dbReference type="OrthoDB" id="1800754at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022781">
        <property type="entry name" value="Flagellar_biosynth_FliO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04347">
        <property type="entry name" value="FliO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03500">
        <property type="entry name" value="FliO_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="124" mass="13233" checksum="5E179A61B2CBDA4D" modified="2008-04-29" version="1" precursor="true">MLSLLVGGATSASELATPLEKGTGMDALLNMMGGLILVLVLIFVLAYIVKRLNLVPASNGVLKMVAATPLGQREKVVLIEVEGQQYLLGVTAQQVNLIDKLDTAVKTDPDSFATRLRQAKTKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLM3</accession>
    <name>B1KLM3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Anaerobic ribonucleoside-triphosphate reductase</fullName>
            <ecNumber evidence="8">1.17.4.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_3049</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.17.4.2" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325656.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3049"/>
    <dbReference type="EnsemblBacteria" id="ACA87320">
        <property type="protein sequence ID" value="ACA87320"/>
        <property type="gene ID" value="Swoo_3049"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3049"/>
    <dbReference type="eggNOG" id="COG1328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002707_2_0_6"/>
    <dbReference type="OMA" id="YSYDRVP"/>
    <dbReference type="OrthoDB" id="195920at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01675">
        <property type="entry name" value="RNR_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012833">
        <property type="entry name" value="NrdD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13597">
        <property type="entry name" value="NRDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02487">
        <property type="entry name" value="NrdD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0556">Organic radical</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="7">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="6">
        <location>
            <begin position="582"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="5">
        <location>
            <position position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA87320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="705" mass="78964" checksum="42CDCC4DF360B57D" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLP7</accession>
    <name>B1KLP7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325680.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3073"/>
    <dbReference type="EnsemblBacteria" id="ACA87344">
        <property type="protein sequence ID" value="ACA87344"/>
        <property type="gene ID" value="Swoo_3073"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3073"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1577434_0_0_6"/>
    <dbReference type="OMA" id="WHRHIRD"/>
    <dbReference type="OrthoDB" id="1789444at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="169" mass="20126" checksum="5B3AFE7447CEFE21" modified="2008-04-29" version="1">MIYSFRNSGFRDPETGVYNQTYFMEVFNREWHRHIREHQSLALLYLCPHIHETVKQPHLLEFFMKEVQKAILRTTDLVARMDNDHFALGLFNINEDGTQIVLERIEKKIETFNLEYGKQHTSHVDFELAACVCLPERDLNIELLFQDVEKLSHELELEQSKHTALRLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ2</accession>
    <name>B1KLQ2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MotA/TolQ/ExbB proton channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Swoo_3078</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325685.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3078"/>
    <dbReference type="EnsemblBacteria" id="ACA87349">
        <property type="protein sequence ID" value="ACA87349"/>
        <property type="gene ID" value="Swoo_3078"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3078"/>
    <dbReference type="eggNOG" id="COG0811">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047225_1_0_6"/>
    <dbReference type="OMA" id="LMLMHAI"/>
    <dbReference type="OrthoDB" id="1796180at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017270">
        <property type="entry name" value="MotA/TolQ/ExbB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037714">
        <property type="entry name" value="TolR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764643" evidence="9">
        <location>
            <begin position="24"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="10">
        <location>
            <begin position="315"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="30"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="451" mass="48595" checksum="902BBCD431CAFE38" modified="2008-04-29" version="1" precursor="true">MKKFISTAIVAATLSLTAGMVSAADAPKSIDQLLKQVQSERATAAKTNKNREAEFRAERGDKAALLKREKAALAAEEQRGKDLTQAFADNERKIAQLEEDRKIAQGDLGEMFGVVKGEAGDFAGKLASSNVTAQYPGRDKFIAELGARKELPKIEELEKFWEDQLFEMAESGKVVTFDGSVTGLDGGVHNTTVTRVGAYNLLADGKYVVYNADLGLIQELSQQPGGEQVSSVKNFTSTTSGYEKLFVDPARGVLLSVFTQKATIEERIEAGGPIGYIIIGLLILGALIFIERLITLYLVGAKVKSQRKNLEEPGNNPLGRILKTYQENKDVDVETLELKLDEAILKETPALETRISIIKVLAAIAPMMGLLGTVTGMIATFQTIQLFGTGDPRLMAGGISMALMTTVQGLVAALPLMLMHAIVIARSKSVVQVLEEQSAGIVAAHAEKRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLQ8</accession>
    <name>B1KLQ8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Porin Gram-negative type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_3084</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Gram-negative porin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325691.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3084"/>
    <dbReference type="EnsemblBacteria" id="ACA87355">
        <property type="protein sequence ID" value="ACA87355"/>
        <property type="gene ID" value="Swoo_3084"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3084"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058202_1_0_6"/>
    <dbReference type="OMA" id="NMTREAD"/>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001897">
        <property type="entry name" value="Porin_gammaproteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001702">
        <property type="entry name" value="Porin_Gram-ve"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00267">
        <property type="entry name" value="Porin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00183">
        <property type="entry name" value="ECOLIPORIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002765030" evidence="5">
        <location>
            <begin position="22"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA87355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="402" mass="44539" checksum="C4CFCFB6BCB56DFB" modified="2008-04-29" version="1" precursor="true">MKKTLVASALAAVIFVPTASAIEIYKDDKNAVEIGGYVDARIINTQGETEVVNGASRINFGFTREMSDGWKAFTKLEWGVNPFGNSEIVYSSESNFESKSGDFLNNRLGYVGLGHDTYGTLTIGKQWGAWYDVVYNTNYGFVWDGNASGTYTYNKADGAVNGTGRGDKVVQYRNSFGDVSFALQAQLKNDTFYTCESISGLGTDCEQRWNDGDESQEVDYGYTYGGAITYQATDMLTLTAGINRGEFDVRFHTGEQITATDLIYGVGATWGSFDQDGFYAAANFNKNENHDTDNLGRLIKDSYGIESLFSYKFENGLRPFISYNVLDAGSDYVIQPNNVDPNDVFKRQFVVAGLHYVWDSNTVLYVEARKDFSDFTSADKAQEARMSISEEDGVAIGIRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLV7</accession>
    <name>B1KLV7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327162.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4587"/>
    <dbReference type="EnsemblBacteria" id="ACA88837">
        <property type="protein sequence ID" value="ACA88837"/>
        <property type="gene ID" value="Swoo_4587"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4587"/>
    <dbReference type="eggNOG" id="COG1022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_45_5_6"/>
    <dbReference type="OMA" id="IAKCPIV"/>
    <dbReference type="OrthoDB" id="164380at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="551" mass="61087" checksum="5655374FBFFDBBA6" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>B1KLX6</accession>
    <name>B1KLX6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327181.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4606"/>
    <dbReference type="EnsemblBacteria" id="ACA88856">
        <property type="protein sequence ID" value="ACA88856"/>
        <property type="gene ID" value="Swoo_4606"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4606"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024648_4_1_6"/>
    <dbReference type="OMA" id="LPMAFNR"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="14"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="420" mass="46512" checksum="810CEA33BC25B0BD" modified="2008-04-29" version="1">MQTASATQGKQADIDVVIIGAGPSGSIAASLLHQAGKRVVVIEKQHFPRFSIGESLLPCCMQLIEEANMLDAVNAAGFQFKNGAAFRYRDQYINFDFTDKFTPGPGTTFQVERGNFDKLLADTAAEQGVEIRYGETVESVDLSADPTLSIRDEAGKLYTIEAKYLLDASGFGRVLPRLLNLEKPSNLANRSAVFTHIQDNIGDKEVDGKPFDRNKILVSVHPKNRDIWYWLIPLSEGKCSLGVVGEPHLLSGLEDNLEEMLLDMVKQEPGLNQLLSDAEVLRECALLKGYSANVSTLATDKFALLGNAGEFLDPVFSSGVTIAMQSASMAVKCIARQLNGTPVNWEQEYSIPLMRGVDTFRTYVEAWYDGRFQDVIFYDDPDNKIKQMICSILAGYAWDESNPFVNDSRKRLNLIVELCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMC7</accession>
    <name>B1KMC7_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2726 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322889.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0239"/>
    <dbReference type="EnsemblBacteria" id="ACA84540">
        <property type="protein sequence ID" value="ACA84540"/>
        <property type="gene ID" value="Swoo_0239"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0239"/>
    <dbReference type="eggNOG" id="ENOG5031E5D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1625927_0_0_6"/>
    <dbReference type="OMA" id="HLAKNDC"/>
    <dbReference type="OrthoDB" id="1522332at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024402">
        <property type="entry name" value="DUF2726"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10881">
        <property type="entry name" value="DUF2726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2726" evidence="2">
        <location>
            <begin position="58"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="163" mass="18341" checksum="31D9B7092A229245" modified="2008-04-29" version="1">MNASIILNYAFVYFVLFLVVPFVLVTFTLTCIKFFKSSEQSITNVKLRTYTLEGEPVGFVNKLNNLVNGKYNVLYGTTLDSIFDVDKGDSEEHAHHYLQSCHLDYVLVDNESSAIKLVITDPQHNSEENSRYIDNALAKMGVKVLHLAKNDCDETLLRASLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMG5</accession>
    <name>B1KMG5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ASPIC/UnbV domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324309.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1678"/>
    <dbReference type="EnsemblBacteria" id="ACA85963">
        <property type="protein sequence ID" value="ACA85963"/>
        <property type="gene ID" value="Swoo_1678"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1678"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_288340_0_0_6"/>
    <dbReference type="OrthoDB" id="315695at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07593">
        <property type="entry name" value="UnbV_ASPIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767205" evidence="4">
        <location>
            <begin position="45"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="domain" description="UnbV_ASPIC" evidence="5">
        <location>
            <begin position="993"/>
            <end position="1060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1066" mass="117837" checksum="97D8A342C6E6F1DB" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH3</accession>
    <name>CYSD_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfate adenylyltransferase subunit 2</fullName>
            <ecNumber evidence="1">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP-sulfurylase small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Sulfate adenylate transferase</fullName>
            <shortName evidence="1">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysD</name>
        <name type="ordered locus">Swoo_1686</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H(+) + sulfate = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer composed of CysD, the smaller subunit, and CysN.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324317.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMH3"/>
    <dbReference type="SMR" id="B1KMH3"/>
    <dbReference type="STRING" id="392500.Swoo_1686"/>
    <dbReference type="PRIDE" id="B1KMH3"/>
    <dbReference type="EnsemblBacteria" id="ACA85971">
        <property type="protein sequence ID" value="ACA85971"/>
        <property type="gene ID" value="Swoo_1686"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1686"/>
    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043026_0_0_6"/>
    <dbReference type="OMA" id="LMIDTGH"/>
    <dbReference type="OrthoDB" id="499077at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00064">
        <property type="entry name" value="Sulf_adenylyltr_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011784">
        <property type="entry name" value="SO4_adenylTrfase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002936">
        <property type="entry name" value="CysDAde_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02039">
        <property type="entry name" value="CysD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000092226" description="Sulfate adenylyltransferase subunit 2">
        <location>
            <begin position="1"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00064"/>
        </source>
    </evidence>
    <sequence length="301" mass="34797" checksum="2CAC62316EC47FA8" modified="2008-04-29" version="1">MSTHQTHLKQLEAESIQIMREVAAEFDNPVMLYSVGKDSSVLLHLARKAFYPGKIPFPLMHVDTNWKFKEMIEFRDQMAEKHGFDLIVHKNPRGLEMNISPFTHGSAKHTDIMKTEGLKQALDAHGFDAAFGGARRDEEKSRAKERVYSFRDNKHRWDPKNQRPELWNIYNGKVDKGESIRVFPLSNWTELDIWQYIYLEGIEIPSLYLATERPVVERDGTLIMVDDERMPLEADEDVQNKMVRFRTLGCYPLTGAVESQAQTLPEIIQEMLLCTTSERQGRVIDNDSAGSMEKKKIEGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMH6</accession>
    <name>B1KMH6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="2 3">2.7.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">APS kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">ATP adenosine-5'-phosphosulfate 3'-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Adenosine-5'-phosphosulfate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cysC</name>
        <name evidence="4" type="ordered locus">Swoo_1689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2 3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the APS kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="2 3"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324320.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1689"/>
    <dbReference type="EnsemblBacteria" id="ACA85974">
        <property type="protein sequence ID" value="ACA85974"/>
        <property type="gene ID" value="Swoo_1689"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1689"/>
    <dbReference type="eggNOG" id="COG0529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046932_1_0_6"/>
    <dbReference type="OMA" id="GVTIWFT"/>
    <dbReference type="OrthoDB" id="1574819at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="2">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA85974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="222" mass="24554" checksum="D7B7E3AFA42AED7C" modified="2008-04-29" version="1">MDIFMSSLSKTSASPYQEIEVEDKSSDVVWHNASVSHEQRVAAQGHKPAVLWFTGLSGSGKSTVANAVDKLLYDLGCKTYLLDGDNVRHGLNGDLGFSDKDRVENIRRIGEVSKLFVDAGLLVSTAFISPFIADRDLVRKQLADKQFIEVFIDTPLEVCEERDPKGLYKKARAGEIKNFTGIDSAYELPKLPEIHVKTAEKSIKACAEQVVNYLIVNGYINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ5</accession>
    <name>B1KMQ5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3162"/>
    <dbReference type="EnsemblBacteria" id="ACA87433">
        <property type="protein sequence ID" value="ACA87433"/>
        <property type="gene ID" value="Swoo_3162"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3162"/>
    <dbReference type="eggNOG" id="COG3313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162538_6_2_6"/>
    <dbReference type="OMA" id="DIREWRS"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010710">
        <property type="entry name" value="DUF1289"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35175">
        <property type="entry name" value="PTHR35175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06945">
        <property type="entry name" value="DUF1289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="81" mass="8974" checksum="D48A8E37177CE26D" modified="2008-04-29" version="1">MIQSPCVAKCGVNEDDICMGCYRNIDEIVGWSKADNAFKAEVWKQIPARKAALGKGENSQKISRDKWQEVAARLESDTAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMQ8</accession>
    <name>B1KMQ8_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_3165</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325772.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3165"/>
    <dbReference type="EnsemblBacteria" id="ACA87436">
        <property type="protein sequence ID" value="ACA87436"/>
        <property type="gene ID" value="Swoo_3165"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3165"/>
    <dbReference type="eggNOG" id="COG0704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078518_2_1_6"/>
    <dbReference type="OMA" id="WKHGIET"/>
    <dbReference type="OrthoDB" id="1648549at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="27"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="128"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA87436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="26720" checksum="D52E0F0FF571FE94" modified="2008-04-29" version="1">MENMNLSKHISGQFNAELDDIRNRVLAMGGLVERQLEQSLDALSALDAELAQKVIEGDHKVNGMEVAIDEECTRIIAKRQPAASDLRLVLAISKTITDLERIGDACVKIAKAAMDKRSKNQQPLLVSIENMGRHATRLLHATLDALARMDAEVALELHKEDFKIDKEYEGIIRQLMTYMMADPRSIPEVLDVLWAARAVERVGDRCQNICEYIIYYVKGKDVRHVSYEEMEKDLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMU1</accession>
    <name>B1KMU1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325805.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3199"/>
    <dbReference type="EnsemblBacteria" id="ACA87469">
        <property type="protein sequence ID" value="ACA87469"/>
        <property type="gene ID" value="Swoo_3199"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3199"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_6"/>
    <dbReference type="OMA" id="WERFEND"/>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="257" mass="27133" checksum="B968178ADE843D42" modified="2008-04-29" version="1">MTGIVERIEGHTAILTMSNPPANTWTDTSLQALKHKVLELNSNKDIYALVITGEGEKFFSAGADLKLFADGDKGVAASMAKYFGEAFEALSQFRGVSIAAINGYAMGGGLEVALACDIRIAEAQAVMALPEASVGLLPCAGGTQNLTALVGEGWAKRMILCGERVKADKAEALGLVEEVVETGKSLDAAIALAEKVANQSPSSVTVCKQLIQAGRTMPRTLALPLERELFVGLFDTEDQAEGVNAFLDKRSANWKNG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMY2</accession>
    <name>RL4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplD</name>
        <name type="ordered locus">Swoo_4689</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327259.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMY2"/>
    <dbReference type="SMR" id="B1KMY2"/>
    <dbReference type="STRING" id="392500.Swoo_4689"/>
    <dbReference type="EnsemblBacteria" id="ACA88939">
        <property type="protein sequence ID" value="ACA88939"/>
        <property type="gene ID" value="Swoo_4689"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4689"/>
    <dbReference type="eggNOG" id="COG0088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_5_2_6"/>
    <dbReference type="OMA" id="PQVHILE"/>
    <dbReference type="OrthoDB" id="1572673at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142187" description="50S ribosomal protein L4">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="201" mass="22049" checksum="48ADE6A577FD5839" modified="2008-04-29" version="1">MELVLKDAQSALEVSETTFGRDFNEALVHQVVVAYAANARQGTRAQKTRAEVVGSGKKPWRQKGTGRARAGTVKGPIWRGGGVTFAAKAQDHSQKVNKKMYRGALKSIFSELVRQDRLIVVESFGVEAPKTKELKAKLAEMNLEDVLIVTPEIDENLFLAARNLYKVDVRDVAGIDPVSLIAFNKVLVTADAVKQIEEMLG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMY4</accession>
    <name>RS10_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsJ</name>
        <name type="ordered locus">Swoo_4691</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005503530.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KMY4"/>
    <dbReference type="SMR" id="B1KMY4"/>
    <dbReference type="STRING" id="392500.Swoo_4691"/>
    <dbReference type="EnsemblBacteria" id="ACA88941">
        <property type="protein sequence ID" value="ACA88941"/>
        <property type="gene ID" value="Swoo_4691"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4691"/>
    <dbReference type="eggNOG" id="COG0051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122625_1_3_6"/>
    <dbReference type="OMA" id="QFEIRVH"/>
    <dbReference type="OrthoDB" id="2012682at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000127183" description="30S ribosomal protein S10">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <sequence length="103" mass="11771" checksum="A65AC52D19F25804" modified="2008-04-29" version="1">MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILTSPHVNKDARDQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>B1KMZ6</accession>
    <name>B1KMZ6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="8" type="ordered locus">Swoo_4703</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327271.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4703"/>
    <dbReference type="EnsemblBacteria" id="ACA88953">
        <property type="protein sequence ID" value="ACA88953"/>
        <property type="gene ID" value="Swoo_4703"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4703"/>
    <dbReference type="eggNOG" id="COG0690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113663_0_1_6"/>
    <dbReference type="OMA" id="FLWLTDK"/>
    <dbReference type="OrthoDB" id="1974284at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01650">
        <property type="entry name" value="SECETRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01067">
        <property type="entry name" value="SECE_SEC61G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA88953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="123" mass="13272" checksum="E182AF30769FB27D" modified="2008-04-29" version="1">MTTNTESQGNSLDIVKWALVVILLAAAIVGNQMYSEASVLVRAISVVVAFVIAGFIALQTEKGKQALTFAREAQIEVRKVVWPTRQEALNTTFIVLAATGVLALILWGMDAVLLRIVNFITGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN50</accession>
    <name>B1KN50_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TerB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322896.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84547">
        <property type="protein sequence ID" value="ACA84547"/>
        <property type="gene ID" value="Swoo_0246"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0246"/>
    <dbReference type="eggNOG" id="COG4103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111095_2_0_6"/>
    <dbReference type="OMA" id="IVEMMWE"/>
    <dbReference type="OrthoDB" id="1863696at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerB" evidence="1">
        <location>
            <begin position="27"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="149" mass="16952" checksum="A770FDFAFAF35B9B" modified="2008-04-29" version="1">MIAKLKQFLTSHSQAVTPEEQTRQLNLAAVSLLLEVVFADETLSNEEAKLLPSMLTDALSLTQSEAEELIEEATKIQGNSTSLYEFTSEINDQCSVEQKQKLILAMWKLAYADGQLCRYEDQIIRRTAELLYLKHSELIQMRNIAMEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>B1KN61</accession>
    <name>B1KN61_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322907.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA84558">
        <property type="protein sequence ID" value="ACA84558"/>
        <property type="gene ID" value="Swoo_0257"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0257"/>
    <dbReference type="eggNOG" id="ENOG5030CCU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161398_0_0_6"/>
    <dbReference type="OMA" id="ESREQKY"/>
    <dbReference type="OrthoDB" id="2083191at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA84558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="118" mass="13802" checksum="27579CBB44B3F004" modified="2008-04-29" version="1" precursor="true">MEFSINNWLKLFPVLILTTLLFSTASLAKDKLSLSEKADAADKLSQDLESEQLQKAREAARDTKVRERKILKRQESGDWETEQRDKAQKQFHERESRQDKYLREAKEAAAKERKIPKP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNL5</accession>
    <name>Y1808_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0227 protein Swoo_1808</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Swoo_1808</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0227 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324438.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KNL5"/>
    <dbReference type="SMR" id="B1KNL5"/>
    <dbReference type="STRING" id="392500.Swoo_1808"/>
    <dbReference type="ESTHER" id="shewm-y1808">
        <property type="family name" value="abh_upf00227"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86092">
        <property type="protein sequence ID" value="ACA86092"/>
        <property type="gene ID" value="Swoo_1808"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1808"/>
    <dbReference type="eggNOG" id="COG3150">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128769_0_0_6"/>
    <dbReference type="OMA" id="KCVSEFR"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01047">
        <property type="entry name" value="UPF0227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022987">
        <property type="entry name" value="UPF0227"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008886">
        <property type="entry name" value="UPF0227/Esterase_YqiA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35602">
        <property type="entry name" value="PTHR35602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05728">
        <property type="entry name" value="UPF0227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000136202" description="UPF0227 protein Swoo_1808">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01047"/>
        </source>
    </evidence>
    <sequence length="179" mass="20514" checksum="E2251BB401752BAC" modified="2008-04-29" version="1">MILYLHGFDATSPGNHEKIRQLQFIDKDVRLLSYSTLHPKHDMQHLLNEVSKQLKLTDDSEPIIIGVGLGGYWAERIGYLNGLKSVLINPNLTPQDNMLGKIDRPEEYSDIANKCVSEFREKNSGKSLVILSRNDDTFDNQVVSDELSRFYEICWDEEQPHKFPVLASQLPRIQAFKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNM1</accession>
    <name>B1KNM1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein-releasing system ATP-binding protein LolD</fullName>
            <ecNumber evidence="6">7.6.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lolD</name>
        <name evidence="8" type="ordered locus">Swoo_1814</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.-" evidence="6"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324444.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1814"/>
    <dbReference type="EnsemblBacteria" id="ACA86098">
        <property type="protein sequence ID" value="ACA86098"/>
        <property type="gene ID" value="Swoo_1814"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1814"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_6"/>
    <dbReference type="OMA" id="HDMSLAR"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044873">
        <property type="term" value="P:lipoprotein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011924">
        <property type="entry name" value="LolD_lipo_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02211">
        <property type="entry name" value="LolD_lipo_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA86098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="236" mass="25940" checksum="DC37FB1F15B408AB" modified="2008-04-29" version="1" precursor="true">MPELLLEVKSVSKRFQEGTVDTQVLTSVDLQVFKGEQLAIIGTSGSGKSTLLHIMGTLDKPSSGHVFMLGEDLYGLSPRRQSEVRNQDLGFIYQFHHLLPEFSALENVAMPALIQGRNRKEVEVEAKALLERVGLGHRFDHTPGEMSGGERQRTAIARALINKPKLVLADEPTGNLDATSGEAVYELIRELANQLGTAFVVVTHDAKLAARMDRQLKMKDGHLQSEQLTDVEGKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>B1KNU5</accession>
    <name>B1KNU5_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional uridylyltransferase/uridylyl-removing enzyme</fullName>
            <shortName evidence="8">UTase/UR</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Bifunctional [protein-PII] modification enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Bifunctional nitrogen sensor protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="8">[Protein-PII] uridylyltransferase</fullName>
                <shortName evidence="8">PII uridylyltransferase</shortName>
                <shortName evidence="8">UTase</shortName>
                <ecNumber evidence="8">2.7.7.59</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">[Protein-PII]-UMP uridylyl-removing enzyme</fullName>
                <shortName evidence="8">UR</shortName>
                <ecNumber evidence="8">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">glnD</name>
        <name evidence="11" type="ordered locus">Swoo_3283</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13673"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
            <dbReference type="EC" id="2.7.7.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:48600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14253"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:77828"/>
            <dbReference type="EC" id="3.1.7.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GlnD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.59" evidence="8"/>
    <dbReference type="EC" id="3.1.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325889.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3283"/>
    <dbReference type="EnsemblBacteria" id="ACA87553">
        <property type="protein sequence ID" value="ACA87553"/>
        <property type="gene ID" value="Swoo_3283"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3283"/>
    <dbReference type="eggNOG" id="COG2844">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012833_0_0_6"/>
    <dbReference type="OMA" id="WIAKYVY"/>
    <dbReference type="OrthoDB" id="162558at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008893">
        <property type="term" value="F:guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00277">
        <property type="entry name" value="PII_uridylyl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010043">
        <property type="entry name" value="UTase/UR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47320">
        <property type="entry name" value="PTHR47320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006288">
        <property type="entry name" value="PII_uridyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01693">
        <property type="entry name" value="UTase_glnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2 8 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="10">
        <location>
            <begin position="436"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="677"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="785"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uridylyltransferase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACA87553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="859" mass="97823" checksum="A0FBB3F60AA9988E" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KP62</accession>
    <name>B1KP62_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_4844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327410.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4844"/>
    <dbReference type="EnsemblBacteria" id="ACA89093">
        <property type="protein sequence ID" value="ACA89093"/>
        <property type="gene ID" value="Swoo_4844"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4844"/>
    <dbReference type="eggNOG" id="ENOG5033STF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_323348_0_0_6"/>
    <dbReference type="OrthoDB" id="663548at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767263" evidence="1">
        <location>
            <begin position="20"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA89093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="894" mass="98807" checksum="C6EC44F7DA332930" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPF9</accession>
    <name>B1KPF9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Swoo_1828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324458.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1828"/>
    <dbReference type="EnsemblBacteria" id="ACA86112">
        <property type="protein sequence ID" value="ACA86112"/>
        <property type="gene ID" value="Swoo_1828"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1828"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_6"/>
    <dbReference type="OMA" id="MEDQAYG"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="839"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="867"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="893"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="941"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="970"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACA86112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="1025" mass="113291" checksum="EF85B455FA161A32" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPG1</accession>
    <name>B1KPG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1830</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324460.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1830"/>
    <dbReference type="EnsemblBacteria" id="ACA86114">
        <property type="protein sequence ID" value="ACA86114"/>
        <property type="gene ID" value="Swoo_1830"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1830"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_2_6"/>
    <dbReference type="OMA" id="QATMPIF"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002764722" evidence="3">
        <location>
            <begin position="29"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="67"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="359" mass="39764" checksum="18BF6A13EE928836" modified="2008-04-29" version="1" precursor="true">MDSLNKRANNYFKLALPLVLVGVLSACGAEEEIKEEEKYAVPVETTTVIQGDVSSFYSTTATLEAPQEANVVTRISGLIESINVEEGDRVTKGQLLAVIDAKRQKYELARSQAEVEIIEQELNRLKKMNNKEFFSADSMAKLEYNLQAAIAKRDLAALQVEESMVRSPIDGVIATRFVKAGNMAKEFEELFYVVDQDELYGIVHLPEQQLESLKLGQDAQIFANKNTQDTVHAKVLRISPVVDAQSGTFKVTLSVPNSDSKLKAGMFTRVELRYDTHNNVITVPYNAVVNQDNEFALYVIDGTNANRRSVSLGYREADTVEVVSGIEPGEQIVIRGHQNLKDQSLVEVISSLDLASTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>B1KPI7</accession>
    <name>B1KPI7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA86140">
        <property type="protein sequence ID" value="ACA86140"/>
        <property type="gene ID" value="Swoo_1856"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1856"/>
    <dbReference type="HOGENOM" id="CLU_2234745_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="11177" checksum="5866456148598A37" modified="2008-04-29" version="1" precursor="true">MLLAVSTRILPFIGNTLYVNYSLNGIIMLKKSYCAALLTTLLISTSSMAGTLNVEPNKGGAAERANTQLSNGNTQSVADIDIKAVLSPTLNLRPQIGVRRPMGDL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-02-10" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ40</accession>
    <name>ATP6_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpB</name>
        <name type="ordered locus">Swoo_4904</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA89153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012327469.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KQ40"/>
    <dbReference type="SMR" id="B1KQ40"/>
    <dbReference type="STRING" id="392500.Swoo_4904"/>
    <dbReference type="EnsemblBacteria" id="ACA89153">
        <property type="protein sequence ID" value="ACA89153"/>
        <property type="gene ID" value="Swoo_4904"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4904"/>
    <dbReference type="eggNOG" id="COG0356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041018_1_0_6"/>
    <dbReference type="OMA" id="FTHAVRL"/>
    <dbReference type="OrthoDB" id="867266at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="PTHR42823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0138">CF(0)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000362463" description="ATP synthase subunit a">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <sequence length="264" mass="29507" checksum="5AC519EB71D3C554" modified="2008-04-29" version="1">MAATGEALTPQGYIQHHLTNLSVGEGFWTWHIDSLFFSVGLGVLFLWLFRSVGKKATTGVPGKLQCFVEMIVEFVDSSVKETFHGRNPVIAPLALTIFVWVFMMNFMDMVPVDWIPELAMAAGIPYMKVVPTTDLNITFSMAIGVFLLIIYYSIKVKGISGFVKELTLQPFNHKAMIPVNLLLETVTLIAKPISLALRLFGNLYAGELIFILIALMYGANWALSTLGVTLQLGWLIFHILVITLQAFIFMMLTIVYLSMAHEDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQ99</accession>
    <name>B1KQ99_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_0456</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323103.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0456"/>
    <dbReference type="EnsemblBacteria" id="ACA84754">
        <property type="protein sequence ID" value="ACA84754"/>
        <property type="gene ID" value="Swoo_0456"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0456"/>
    <dbReference type="eggNOG" id="COG4783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029002_0_2_6"/>
    <dbReference type="OMA" id="EQHGIRN"/>
    <dbReference type="OrthoDB" id="1530824at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="185"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA84754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="395" mass="43665" checksum="74EDEEEDDD8D0849" modified="2008-04-29" version="1">MSEVRSEYLYPCHGIHSALPKGRASGQLTICKTHLMFTVNDKTVQLGFAELEISQGGASDRLIFFNHPACADWRFYCSDRSVLKNPYLKQAPHLNSVMAKATRKRQFNWLVLTVVVLLCVLVPVGLLANLGTGSKMIAKQVPVEWEESLGSSSFDQYSLQSELMDEQRGELLLAPLVQPLLEVLPNKRYQYQFYISDDSELNAFALPGGVVVINSGLILAADSPEELLGVLSHEIVHVREQHGIRNLISSAGTYLILSAILGDVSGLMAVVVDSAPLLINQGYSRQFETQADEQGFDMLVTANIDPKGLPLFFNKLLDKEAKMLESIEDEDQRGLIETGLGFLSSHPATKDRIENLEARAASIDAEFIVLDEAFFKLQDAVAEFVVKHEEPESGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQI6</accession>
    <name>B1KQI6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Swoo_1941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324571.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1941"/>
    <dbReference type="EnsemblBacteria" id="ACA86225">
        <property type="protein sequence ID" value="ACA86225"/>
        <property type="gene ID" value="Swoo_1941"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1941"/>
    <dbReference type="eggNOG" id="COG2515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061664_0_0_6"/>
    <dbReference type="OMA" id="NKARKFM"/>
    <dbReference type="OrthoDB" id="1714795at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="PTHR43780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACA86225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="305" mass="34696" checksum="3A68176CC43D4092" modified="2008-04-29" version="1">MKLSNTPVDSLMMFDRQIFIKRDDLLHPEFSGNKARKFAYFLAHDFPGAKKLIGYGSPQANSLYSMSALAKLKGWTLDFYVDHIAAQVKSQTEGNYVEACANGANVIDLSERHDREGRSCEEYIKEKALIDETQALFVPEGGRCEYAEFGVAQLAREIVDWAVQANLEQLKVFLPSGTGTTALFLNKYFIESGSNIRVLTCACVGGDEYLNLQFTQLSQFKTFYPEIISLPKKYHFGKLYRECYEMWQRIDKQGIRFELLYDPVGWIALEAYLKSASEQTSIIYIHQGGLLGNASMLPRYKRKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>B1KQT2</accession>
    <name>B1KQT2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326023.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA87688">
        <property type="protein sequence ID" value="ACA87688"/>
        <property type="gene ID" value="Swoo_3420"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3420"/>
    <dbReference type="HOGENOM" id="CLU_962771_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767303" evidence="1">
        <location>
            <begin position="23"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA87688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="31477" checksum="1CFF318FC666E8A8" modified="2008-04-29" version="1" precursor="true">MKTTTLIWLIALPLLGLTNAHAENRSPTKKATMIKMQHQAISSNQAVDNALAFSIPKNMNKKLNVIQWTMNAGTVGRPILSGNRYQLVNLASNCGLKHQKRTFAANLGCRKPSSKKMNLLVKRKKGDGQLRYGDVVALNLNPYGWLKYKRQKKGINISDDNHNPHFIWKIGGGKNGTKLLSGMPFSLYNIKPNKNYVIYCKRTWGIDFGYFKTTKCGGWSANLSGKVFGANGALSGDGMAGNLAKNWRDKLCKAAVGSASAYITAQSGGTTGVAVAAAAPKAIKKCNKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR38</accession>
    <name>B1KR38_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0559</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323203.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0559"/>
    <dbReference type="EnsemblBacteria" id="ACA84855">
        <property type="protein sequence ID" value="ACA84855"/>
        <property type="gene ID" value="Swoo_0559"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0559"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_19_6"/>
    <dbReference type="OMA" id="GMGHELE"/>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="442"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="501"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA84855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="773" mass="84269" checksum="358FD896C69CCA3D" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>B1KR80</accession>
    <name>B1KR80_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323245.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0601"/>
    <dbReference type="EnsemblBacteria" id="ACA84897">
        <property type="protein sequence ID" value="ACA84897"/>
        <property type="gene ID" value="Swoo_0601"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0601"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_35_0_6"/>
    <dbReference type="OMA" id="RRINDHP"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="304" mass="34132" checksum="DD99FBA81F08D648" modified="2008-04-29" version="1">MKIQFESLSAFIAAADTGSFSAAGRKLKKSQAAISLAIQNLEIDLGFTLFDRDGKYPKLTQQGELVLKDARELMSQYSAFIERSKSISSVEQVKLRIGIDPLVCCHKINEIIQDFSMAFPLVELKIVQQSSESLAQKLTDKTLDFALGVFSRDVKNNFEHVSAFQLNGSWVVSPTYVEDNQLRLDNGVVNIEKTVFNQSRILLPSETPLTDIDEVSLTKQIWYVEDIHTLLSFCRNGLGIAYLPNFVVGHDLERGSLNKLMLDSEQTGNNSCRASLIYLLGYQKSSAVDWLTRNFLKFKLCDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRA0</accession>
    <name>B1KRA0_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_2023</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324653.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2023"/>
    <dbReference type="EnsemblBacteria" id="ACA86307">
        <property type="protein sequence ID" value="ACA86307"/>
        <property type="gene ID" value="Swoo_2023"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2023"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_8_6"/>
    <dbReference type="OMA" id="IWGDADQ"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="290"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA86307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="395" mass="42377" checksum="69BF989C375804FE" modified="2008-04-29" version="1" precursor="true">MSSQTIKVIWINIISLPTRLRSSIVAIVGSAGVVAVLVTVLAMAQGFEDALKAPNQSNLFVILKGGATTELVSNITSRSALKLRQHSGIEKANTVSQFSSQLLVAISVPMIGRDADANVSLRGVDQSAYKLHHIHLLKGTLPTTGKREVIVGQRAAEQFEGLQVGSLIGSGTNSWKVVGIFDSQGSIHETEIIADVTMVQNAFQRGNTYSSVHGKLSVSAGASIEQIQTLVENDPELDLVLFKADDYYANQSESLSVFIKSIGYSTAFIMAIGAIFASLNTMYGSVSSRKREFGILRALGYSKLSIAISVFFESALLSLLGGLLGCVVVYLILNNYAVSTFNMLSFSQVAFSFSVTKETMFEGLKWALIIGSLGGCLPALQVSKLTVAETMRKHH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD4</accession>
    <name>SPEA_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Biosynthetic arginine decarboxylase</fullName>
            <shortName evidence="1">ADC</shortName>
            <ecNumber evidence="1">4.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">speA</name>
        <name type="ordered locus">Swoo_2057</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the biosynthesis of agmatine from arginine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + L-arginine = agmatine + CO2</text>
            <dbReference type="Rhea" id="RHEA:17641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="EC" id="4.1.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="1"/>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324686.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KRD4"/>
    <dbReference type="SMR" id="B1KRD4"/>
    <dbReference type="STRING" id="392500.Swoo_2057"/>
    <dbReference type="EnsemblBacteria" id="ACA86341">
        <property type="protein sequence ID" value="ACA86341"/>
        <property type="gene ID" value="Swoo_2057"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2057"/>
    <dbReference type="eggNOG" id="COG1166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027243_1_0_6"/>
    <dbReference type="OMA" id="AVEYTQH"/>
    <dbReference type="OrthoDB" id="164471at2"/>
    <dbReference type="UniPathway" id="UPA00186">
        <property type="reaction ID" value="UER00284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06830">
        <property type="entry name" value="PLPDE_III_ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01417">
        <property type="entry name" value="SpeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040634">
        <property type="entry name" value="Arg_decarb_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041128">
        <property type="entry name" value="Arg_decarbox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002985">
        <property type="entry name" value="Arg_decrbxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295">
        <property type="entry name" value="PTHR43295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17810">
        <property type="entry name" value="Arg_decarb_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17944">
        <property type="entry name" value="Arg_decarbox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001336">
        <property type="entry name" value="Arg_decrbxlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01180">
        <property type="entry name" value="ARGDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01273">
        <property type="entry name" value="speA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0210">Decarboxylase</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="chain" id="PRO_1000145604" description="Biosynthetic arginine decarboxylase">
        <location>
            <begin position="1"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01417"/>
        </source>
    </evidence>
    <sequence length="637" mass="71154" checksum="0609B1DA84469D62" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRD9</accession>
    <name>B1KRD9_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324691.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2062"/>
    <dbReference type="EnsemblBacteria" id="ACA86346">
        <property type="protein sequence ID" value="ACA86346"/>
        <property type="gene ID" value="Swoo_2062"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2062"/>
    <dbReference type="eggNOG" id="ENOG503217S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150725_0_0_6"/>
    <dbReference type="OMA" id="AAQIIMV"/>
    <dbReference type="OrthoDB" id="1759224at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020979">
        <property type="entry name" value="Uncharacterised_A0KLC6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12290">
        <property type="entry name" value="DUF3802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="116" mass="13193" checksum="70F2A6B676BD3174" modified="2008-04-29" version="1">MVTDKDGYTHLIQFLTEHLSLFEGKHDESLTDDTVLELFEEQLAAQIIMVCGQNPSLNFAQRNKVIREVDAIVYDLEEILASVAHQKVTPEQISFITEFSGLIKNLFDQEIAKLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KRE1</accession>
    <name>B1KRE1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324693.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2064"/>
    <dbReference type="EnsemblBacteria" id="ACA86348">
        <property type="protein sequence ID" value="ACA86348"/>
        <property type="gene ID" value="Swoo_2064"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2064"/>
    <dbReference type="eggNOG" id="COG4067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_865716_0_0_6"/>
    <dbReference type="OMA" id="IGRNWLQ"/>
    <dbReference type="OrthoDB" id="1576021at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008503">
        <property type="entry name" value="Put_Zn_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05618">
        <property type="entry name" value="Zn_protease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002767586" evidence="1">
        <location>
            <begin position="19"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Zn_protease" evidence="2">
        <location>
            <begin position="27"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Zn_protease" evidence="2">
        <location>
            <begin position="166"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="289" mass="32177" checksum="BA6D992F404B8AA1" modified="2008-04-29" version="1" precursor="true">MVKIIGFCILFMTTAAWAGDKAIIGPTAHMFVTETGLNFEARIDTGAGNTSLHAYDLEVEGGSAKKMKDNVGKMLMFTTENAAGEKKRLKGKIVKTSTVSNSQGRETRYMVELHVGDKGFERKVKVNLRDRSHMDYKLLIGRNWLKGKYIVDVSDKKLIGPVAPISIVETGLMFKTRIDTGAVENSLHAVDLHVEGGVDDMEKNLGKILSFTTENEKGEAKRVHAMIVETSLIRNAQGSEVRYMVELTIGEKGQEYKVKVNLRDRSKMSNKLLIGRNWLQGHYLVDVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>B1KCX4</accession>
    <name>B1KCX4_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Swoo_0002</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012322652.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0002"/>
    <dbReference type="EnsemblBacteria" id="ACA84303">
        <property type="protein sequence ID" value="ACA84303"/>
        <property type="gene ID" value="Swoo_0002"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0002"/>
    <dbReference type="eggNOG" id="COG0592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038149_4_2_6"/>
    <dbReference type="OMA" id="YLIMPVR"/>
    <dbReference type="OrthoDB" id="1040142at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6 10 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="11">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="12">
        <location>
            <begin position="129"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="13">
        <location>
            <begin position="245"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACA84303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="366" mass="41071" checksum="2FFFD070F43DDE92" modified="2008-04-29" version="1">MKFSIDRDALLKPLQLVTGAVERRHNLPILANLLVEVSGHSLKMTGTDLEVELVGQVQLEGEVQEGRTTIPAKKFLDIVKSLPDQVELKIEQQENRLLLRSGRSRFTLATLPAEEYPNVEAFQAEIEFTINQGTLKSLIDATQFSMANQDVRYYLNGLLLETEGNVLRAIATDGHRLALSHRQIQDTLPEKQVIVPRKGVVELQRLFEGEELDITIAIGDNAIRATTASAVFTSKLVDGRFPDYRRVLPKGGDKVVIASRNHLKQALLRASILSNEKFRGVRVQLEENLIKITANNPEQEEAEEILDVEYENTPLEIGFNVSYLLDVLNNLPSDDVRITLIDGNSSALIENHIEEDSMYVVMPMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>B1KD58</accession>
    <name>B1KD58_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator, CadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326226.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3629"/>
    <dbReference type="EnsemblBacteria" id="ACA87893">
        <property type="protein sequence ID" value="ACA87893"/>
        <property type="gene ID" value="Swoo_3629"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3629"/>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_543904_0_0_6"/>
    <dbReference type="OMA" id="PRKGYAW"/>
    <dbReference type="OrthoDB" id="1007123at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA87893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="501" mass="56344" checksum="79C48ABFF768A2DB" modified="2008-04-29" version="1">MAKVYYGDGFSICCSTHQIQFNDRQVTVRPKTLALIIELIKQQDNVVNKESLLAKVWDDVVCDEQVLFQTISEIRKIFGPIQVIQTYPRKGYAWVATVNSVPCSETVSLTPSQITPSVDLGSENPLGLLLGWGKSKQALPLYFFTVSLLLIFLFFPSKPTTPNDGTVIVLPVVNNVAGQDHLWVPLGAMDQLIGKLSRGAKVMSTEYVLPLVSQIKRTKAYSADELANVFNTTGANLIVESELSGSVHEYKLSYKLHFQHDVKVGVLFSDNVDEALISLAKTVLVYQGGKVEQLRVKFESELKNEMIHRAIALQKEKQLVAANQLLISVLELEPDNNRVRLLLAQWFVEQEMLSRARELLDVAITQVRDKSQARLGRLYYWRAITLFDTAADKAMLELDKSLTYSLKESDSLYLAYASLAKGKLYQLSGKMEKAETAFLNTLNFHRAIFCPMGISTAKLVLAEFYRENGNMALSDEFLMAAREQIELHQLKIDHPLVNFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDI6</accession>
    <name>B1KDI6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323334.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0692"/>
    <dbReference type="EnsemblBacteria" id="ACA84987">
        <property type="protein sequence ID" value="ACA84987"/>
        <property type="gene ID" value="Swoo_0692"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0692"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029030_0_0_6"/>
    <dbReference type="OMA" id="CRRRVNG"/>
    <dbReference type="OrthoDB" id="367541at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="511"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="579"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA84987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="636" mass="72339" checksum="C1C72BCFD7EE9AD7" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDJ3</accession>
    <name>B1KDJ3_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Swoo_0699</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA84994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323341.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0699"/>
    <dbReference type="EnsemblBacteria" id="ACA84994">
        <property type="protein sequence ID" value="ACA84994"/>
        <property type="gene ID" value="Swoo_0699"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0699"/>
    <dbReference type="eggNOG" id="COG1757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018751_1_0_6"/>
    <dbReference type="OMA" id="YTHRHYG"/>
    <dbReference type="OrthoDB" id="776648at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="154"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACA84994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="460" mass="49168" checksum="6DC9C041219F342B" modified="2008-04-29" version="1">MSEPTALSLIPPVVVLVLAIVLRRPILSLIIGALVGLVMFEPENLLTNFTDISLSVMADETIGWLILVCGGFGALIALLVKTGGSMAFGRHALKLAKGPKSSLFMTFILGVVIFIDDYLNALTVGSTMKRVTDKFKVSREMLAYVVDSTAAPICVLVPLSTWAVFFGGLLVDNGIASEGQGIAVYMQAIPYMLYAWLAVAMVLLVILGIVPAFGPMKKAQLAASQGEPALKQIDLDEVQTSDEYAVKAIEDEFKHADEQGKLHNFFVPILLLVGFTVYFDIDVLKGLVATLAVTLPYYGLQKLMPLSEMMEQMIDGFKNMLPAIGTVIAAFIFKDVCDKLMLPQYVIDTLSPFMTPDLLPAVVFLSMSILAFATGSSWGIFAVSIPIVMPLAQSVDANIPLVIGALLSASSFGSQACFYSDSTVLAAQGSGCNLVSHAVTQLPYALIAAAVTFVGFLLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDL4</accession>
    <name>B1KDL4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mammalian cell entry related domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324756.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2127"/>
    <dbReference type="EnsemblBacteria" id="ACA86411">
        <property type="protein sequence ID" value="ACA86411"/>
        <property type="gene ID" value="Swoo_2127"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2127"/>
    <dbReference type="eggNOG" id="COG3008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015836_0_0_6"/>
    <dbReference type="OMA" id="RFWNISG"/>
    <dbReference type="OrthoDB" id="855063at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="41"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="274"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="386"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="513"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="629"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="744"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="874" mass="94393" checksum="849ACCE76B7C0109" modified="2008-04-29" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KDX5</accession>
    <name>B1KDX5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA87977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3717"/>
    <dbReference type="EnsemblBacteria" id="ACA87977">
        <property type="protein sequence ID" value="ACA87977"/>
        <property type="gene ID" value="Swoo_3717"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3717"/>
    <dbReference type="eggNOG" id="COG3050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169027_0_0_6"/>
    <dbReference type="OMA" id="IWDMRGK"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036654">
        <property type="entry name" value="DNA_pol_III_psi_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102220">
        <property type="entry name" value="SSF102220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA87977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="105" mass="11618" checksum="3A3CC90B2EAF6D9E" modified="2008-04-29" version="1">MGISRWSQGGGAVDSYTILLDSLSPELEKHPIITTVLSLIDCPFTHCTFSSSFAKGANVVWDMRRVKLPKSNAVLTSAPLSELEKTAESKRDLWNMILAHQEKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEH4</accession>
    <name>B1KEH4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CopG domain protein DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_2271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324895.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2271"/>
    <dbReference type="EnsemblBacteria" id="ACA86552">
        <property type="protein sequence ID" value="ACA86552"/>
        <property type="gene ID" value="Swoo_2271"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2271"/>
    <dbReference type="eggNOG" id="ENOG5032TX0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165368_1_0_6"/>
    <dbReference type="OMA" id="QLRVNKR"/>
    <dbReference type="OrthoDB" id="1903747at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="2">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA86552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="90" mass="10402" checksum="38C29D51D98D197B" modified="2008-04-29" version="1">MAKETSDRTTIDLFATEKRRGRPRSNPLPRDQQLKVNKRNQIQRDKANGLKRIELKVSQDLYDALNEKALASKISRSQLIELILQNQVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEI7</accession>
    <name>B1KEI7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_2284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012324908.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2284"/>
    <dbReference type="EnsemblBacteria" id="ACA86565">
        <property type="protein sequence ID" value="ACA86565"/>
        <property type="gene ID" value="Swoo_2284"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2284"/>
    <dbReference type="HOGENOM" id="CLU_990062_0_0_6"/>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA86565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="281" mass="32156" checksum="27C55C06D3BE9773" modified="2008-04-29" version="1">MVSLIKHYGYLVLPILFSVPLFGIAETMELKDVKALIEEGRSLEVVNTLKERLNETSEPKKRAELQGAIGWTLVQAKEYEEANKYLESSLVGATDGGYTHIKLRANNNLGILHYLQNDFEVSRSYFNQEIASNSKTAKIYLRLLDIKEREYLGKEALLSGVGKRQSKQFQEAINEYEVSLEHQPNNPKTLEFKGYAEFRLGNLEEAYHTLEQAKHADPKRKFTHLNLLKVSCALKSLQKVLQVINGSELEQEVFIDWAERDLELQRVCDGNEAFTDFIQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN0</accession>
    <name>B1KEN0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_3786</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326376.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3786"/>
    <dbReference type="EnsemblBacteria" id="ACA88045">
        <property type="protein sequence ID" value="ACA88045"/>
        <property type="gene ID" value="Swoo_3786"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3786"/>
    <dbReference type="eggNOG" id="ENOG502ZWH8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1189256_0_0_6"/>
    <dbReference type="OMA" id="TNYVQFS"/>
    <dbReference type="OrthoDB" id="950811at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021974">
        <property type="entry name" value="DUF3581"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12119">
        <property type="entry name" value="DUF3581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="233" mass="26118" checksum="74D88705FA2DA754" modified="2008-04-29" version="1">MFLTPYFKKENQTVTVTPSQASDFAKVVAQDFNPIHDVGAKRFCVPGDLLFSLVLGEYGLSQKMSFTFQGMVGDGVKLQFPGSIGDAFDIHDDKDKLYLNVERQGENRNCGTQIESFIRSYVAFSGLNFIHVLVPMMKQHQVMINPARPLVIYESMSFDLTTLDFTQVTLSLVEQELVVEGKRGNVTLKFELHSGDTLVGTGVKTLVMSGLRPYEADKVQEMCDTYEGRRTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEN5</accession>
    <name>B1KEN5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326381.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3791"/>
    <dbReference type="EnsemblBacteria" id="ACA88050">
        <property type="protein sequence ID" value="ACA88050"/>
        <property type="gene ID" value="Swoo_3791"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3791"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_61_1_6"/>
    <dbReference type="OMA" id="SAHFTAY"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="3"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="389" mass="41823" checksum="AEDF4C5F77A55ECD" modified="2008-04-29" version="1" precursor="true">MKQRLIAWAPVFLLALTAFVFVSTEFVPVGLLAALGQSFGMSAIEVGPMLTAYASVVALASLPAVLLFARFERKKLLLGLMSVFIVSHGICVWAPSYEILLSGRVGIAFTHALFWAIAPALVVRLAPNGQGPQALSIFATGCVLALVLGIPLGRVIGQLVGWRTIFALIGLLTLIMMLLLWRGLPTLPATHGGSWRSLPALVRNKALLWLYLLTIVLVTAHYSVYTYLEPLLQEHFGYSANITTMILLIFGAAGLIGSALFSRYQARHAQQLLTLAILSLGSCMAILPFIANQIWLLLPLSILWGAGMMLMCLSLQSKALKLAPNATDVAMAIYSGLFNVGIGGGALLGSIIAARYGVVENGNWASILVLLASVPLFYLLKARRQEMAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KES8</accession>
    <name>B1KES8_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-FecI sigma factor, FecR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_3834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326423.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3834"/>
    <dbReference type="EnsemblBacteria" id="ACA88093">
        <property type="protein sequence ID" value="ACA88093"/>
        <property type="gene ID" value="Swoo_3834"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3834"/>
    <dbReference type="eggNOG" id="COG3712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050192_0_2_6"/>
    <dbReference type="OrthoDB" id="1381035at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018266">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="126"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="354" mass="39239" checksum="BF338BE124F2A76E" modified="2008-04-29" version="1">MSNVHQLHPGAIDDEQRLDIASDWIAKMDRELTAEEREALAQWLHCDVENLHVLLEIAQMWDKMDELGRLSDIFPKAKPTRKKTPVWMGGIAASILLFLSIGLYQFAQDVEPNAQVTGVIAMQSSYQTAVGESNTINLPDDSILVLNTNSFVQVKYTANERIIELQRGEINIEVAHDKSRPLSVLAGGKVIRAVGTAFNVDVRPSGVELIVTDGKVLVVKKSAEAFLKESHADQPKLMGTALAVAKDERVMLNNREPLPSVASKVAPGEIATKLSWRTGNLIFRGESLEEAMAEISRYTDIHFELADDENLKKIKVAGMFKTGDVNGLLNILDQNFNVSHEKLSRNNIKLNYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEY6</accession>
    <name>B1KEY6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323484.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0842"/>
    <dbReference type="EnsemblBacteria" id="ACA85137">
        <property type="protein sequence ID" value="ACA85137"/>
        <property type="gene ID" value="Swoo_0842"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0842"/>
    <dbReference type="eggNOG" id="COG4968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098637_3_1_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="193" mass="21457" checksum="477F8F051405484F" modified="2008-04-29" version="1">MYLSSKKQKGFTLIELVVVIIILGILAVIALPKFINLNKEADSALVKQHMSAILAGKTLFHSKWNIDQQPSTAFSIYQSTPSELGFPAGGDILDEAFESDCSLIWHDMVEDKEPLNFISGSNGWQSSHVKSEWSRNAGVLPQLGETQDNYCHFVYTGGFYNGSFSGFPDDRLLTIQYNIVSGETKLLSWPYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEY7</accession>
    <name>B1KEY7_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323485.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0843"/>
    <dbReference type="EnsemblBacteria" id="ACA85138">
        <property type="protein sequence ID" value="ACA85138"/>
        <property type="gene ID" value="Swoo_0843"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0843"/>
    <dbReference type="eggNOG" id="COG4637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035814_1_0_6"/>
    <dbReference type="OMA" id="QVWVVSH"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="196"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="393" mass="43867" checksum="E2229C3DD4FE7D2B" modified="2008-04-29" version="1">MLTTLAIQNYRSLREIRVPLERLNLVTGANGSGKSNLYKALRLLAQTAQGGVVNALALEGGLDSSFWAGPETISKGMRSGETPIEPTVRQHAKRLKLGFASDEYSYLIELGLPKPDSTTLFGLDPQVKREAIWVGNRYRPASVLVERRGPLVKSRAEQNKQAGWETLNLHMQHGDSIFTELADPERTPEVIKLRDSIRAWRFYDHFRSDSDAPARKAQLGTRTPVLHHDGRDLASAIQTIFEVGDKQGFNEAVSDAFPGARVHIGYESNGMLTVQFHQEGLLRPLNAAELSDGTLRYLLLVAALLTPRPPELMVLNEPETSLHPYLLPALSRLIAKASEHCQLWVVSHANRLINALNEFEHCNLIELDKQLGQTEILGQDILTTPSWHWQSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>B1KEZ1</accession>
    <name>B1KEZ1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP transporter, 4TM/12TM fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_0847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0847"/>
    <dbReference type="EnsemblBacteria" id="ACA85142">
        <property type="protein sequence ID" value="ACA85142"/>
        <property type="gene ID" value="Swoo_0847"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0847"/>
    <dbReference type="eggNOG" id="COG4666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007041_3_1_6"/>
    <dbReference type="OMA" id="VPFMAVY"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011853">
        <property type="entry name" value="TRAP_DctM-Dct_fused"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02123">
        <property type="entry name" value="TRAP_fused"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="537"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="601"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="2">
        <location>
            <begin position="130"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA85142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="635" mass="66951" checksum="7F5593CE15E2D8FD" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KF29</accession>
    <name>B1KF29_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_0886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323527.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0886"/>
    <dbReference type="EnsemblBacteria" id="ACA85180">
        <property type="protein sequence ID" value="ACA85180"/>
        <property type="gene ID" value="Swoo_0886"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0886"/>
    <dbReference type="eggNOG" id="ENOG503461G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1546558_0_0_6"/>
    <dbReference type="OMA" id="TVCGCRL"/>
    <dbReference type="OrthoDB" id="1642849at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA85180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="172" mass="19575" checksum="0B5E9E53C79232C0" modified="2008-04-29" version="1">MNRKLLWGINGLILFILIMSVTFSYRQLNPSQELMMSCSSELFDPSNERESKSRHYLLVDLFAKGELAQFNYRYFNHDGSSAGNIRMKGSVVGVDNSAQRYSFSVKTKEESGLDGDEIPEHMSYLSYVSSFNLDKKGMHNLSVEMLDLNEQNDYAVVLFQPSNTVCGCRLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFE4</accession>
    <name>B1KFE4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326449.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3861"/>
    <dbReference type="EnsemblBacteria" id="ACA88119">
        <property type="protein sequence ID" value="ACA88119"/>
        <property type="gene ID" value="Swoo_3861"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3861"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077728_1_1_6"/>
    <dbReference type="OMA" id="YRSAGWT"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="173" mass="19154" checksum="A8138B57112B79C9" modified="2008-04-29" version="1">MQIIELTDLSSSDPSLKNGLALQLKRCVDLGASIGFITPFSERESRYYWDSVETDLNQGGRILLLATENQQVLGTVQLSFCDKKNGRHRAEVEKLMVHPDARGLGIAGKLMHQIEALAKSRGRTLLILDTLTDSLAANLYLKLGFLRVGEIPDFALSTEGELEATCVFYKQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFF5</accession>
    <name>B1KFF5_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3872"/>
    <dbReference type="EnsemblBacteria" id="ACA88130">
        <property type="protein sequence ID" value="ACA88130"/>
        <property type="gene ID" value="Swoo_3872"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3872"/>
    <dbReference type="eggNOG" id="ENOG503096F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1204121_0_0_6"/>
    <dbReference type="OMA" id="DWSQLDF"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="261" mass="29666" checksum="BC95E7D288E26230" modified="2008-04-29" version="1">MHHSDRDISLEATTSINKGAVTARFLIPNKVNSMAQELDTHSPRYDLHRLVVLMILAGAFTSAIGISISVWAEYQHIGTEVFFRRADYLGDYIHSPLAYIYNLSLVIAGSCILLSMYGLFRLKLGYYSHYIAIAGFWVGMSIILIGVFPINYLDEHRLVSTSFLMGTFVLYLLTISLRFNHKGLCSTPLFLISVFGLISATGLIYQLDWQTLDFIPCLHDQGEFCWVSLNMWFQTSITMIWCVVLAFTVRKLSNENYTPDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFG1</accession>
    <name>B1KFG1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aromatic amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Swoo_3878</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326466.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3878"/>
    <dbReference type="EnsemblBacteria" id="ACA88136">
        <property type="protein sequence ID" value="ACA88136"/>
        <property type="gene ID" value="Swoo_3878"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3878"/>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038102_1_0_6"/>
    <dbReference type="OMA" id="SFLGVTM"/>
    <dbReference type="OrthoDB" id="935253at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46997">
        <property type="entry name" value="PTHR46997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACA88136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="391" mass="41244" checksum="B31BEA2BA9E96E3A" modified="2008-04-29" version="1" precursor="true">MLGSIAIVAGTAIGAGMLALPLATAALGIIPAILLLVVIWGVSAYTSLLMLEVNLRTGVGDNLHAITGKILGKRGQLIQGASFLSLLFALTAAYLTGGSSLLVLKAEAMFGIALDNQLAVVIFTLTLGLLAAFGVAWVDKVSRILFSLMIALLVITVGFLLPEISPSQMAIAAIEEGKVDLWMAAIPVVFTSFGFHVCIATLVRYLEGDALTLRKVLLIGSTLPLLCYVLWLLVTLGTVGGEQIHSFGGSLPALITSLQDIASQPWVSKCISLFADFALVTSFIGVTLSLYDFISELTRAKSTIMGRVQTWLITFVPPVLCALYIPEGFVAVLGFAAVPLVFIIIFLPIVMVLKQRKEVTEGYQVCGGKPALTLVGLLGAVIIAAQLMVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFJ1</accession>
    <name>B1KFJ1_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_3908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326496.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_3908"/>
    <dbReference type="EnsemblBacteria" id="ACA88166">
        <property type="protein sequence ID" value="ACA88166"/>
        <property type="gene ID" value="Swoo_3908"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3908"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_2_3_6"/>
    <dbReference type="OMA" id="ICIYGGY"/>
    <dbReference type="OrthoDB" id="1445898at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA88166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="252" mass="26524" checksum="5C189ADB5049AE2E" modified="2008-04-29" version="1" precursor="true">MDITLTHAVLLLVTGFFAGIINTLAGGGSNLTLPALMVMGMPAEVANATNRVGVLMQSIVAVLGFKKHGKLDTDDTVPILIPTIVGGLLGAAGAAYAPSEWIKPLLLGTMLLMAFIILVKPSMVAPELGTPVKQVSQTPASWWWLGVAGFYGGFVQAGVGFVLLAALAGSLRYDLVRANALKMLCTLVFTSVALVLFIIEGLIQWLPGLILALSTMFGAHLAVKLAIKAKPDTLKWFLFIMTLVGCIAAMFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFL0</accession>
    <name>B1KFL0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_3927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACA88185">
        <property type="protein sequence ID" value="ACA88185"/>
        <property type="gene ID" value="Swoo_3927"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_3927"/>
    <dbReference type="eggNOG" id="ENOG50331QF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_192349_0_0_6"/>
    <dbReference type="OMA" id="KMYLTFM"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA88185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="77" mass="8498" checksum="86C91D859911A8CA" modified="2008-04-29" version="1">MMTDNKLILILKCCIAVGICLILLGIYFHNFNEAIEAMGVKGIIISAVCVAFGMALSLPTKMYLTFILVKRESEKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFN6</accession>
    <name>B1KFN6_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_0908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0908"/>
    <dbReference type="EnsemblBacteria" id="ACA85202">
        <property type="protein sequence ID" value="ACA85202"/>
        <property type="gene ID" value="Swoo_0908"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0908"/>
    <dbReference type="eggNOG" id="ENOG50304GT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1601571_0_0_6"/>
    <dbReference type="OMA" id="IEMQYLR"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027909">
        <property type="entry name" value="DUF4447"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027910">
        <property type="entry name" value="YdiL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14590">
        <property type="entry name" value="DUF4447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="185" mass="20921" checksum="A159AAECE203DFFB" modified="2008-04-29" version="1">MISLSIRFKLAKNLNIGNTMSKNMGLNAIEIKYLRLSLGLTTAQVGELSKASEEDVIAWEAGEKPVSGLAEKKLIEIDETIEMQVLNTCDGIEELFKKEPKRQLSFVVYPTQALYAQYNPEFLGALPLTELYNTSAWRIKKECKLILEVDVTLVALEVESYKAYREKEGLKESRESRAKWAATQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>B1KFQ0</accession>
    <name>B1KFQ0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Swoo_0923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323563.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_0923"/>
    <dbReference type="EnsemblBacteria" id="ACA85216">
        <property type="protein sequence ID" value="ACA85216"/>
        <property type="gene ID" value="Swoo_0923"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_0923"/>
    <dbReference type="eggNOG" id="COG1052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_1_6"/>
    <dbReference type="OMA" id="VIVTAHQ"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="5">
        <location>
            <begin position="9"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="6">
        <location>
            <begin position="110"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACA85216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="330" mass="36456" checksum="8D5FBAC1237F5E9D" modified="2008-04-29" version="1">MKIGFFSAKHYDMEHFDRSNKTFGAEIEYFDYRLCMKSVRLAHGFEAICAFVNDSLCEEVLVELARNGTKIIAMRCAGFNNVDLVAAKRLGLRVVNVPAYSPESVAEHTVALMLTLNRKVHKAYQRTRDANFSLEGLVGFNMHGRTVGVIGTGKIGVATIKILQGFGCKVIAHDPYPNPQVVNLGIEYQPLDELYSVSDIITLHCPLTPANHHLLSAETFDKMKPGVMVINTSRGGLLNAMDAMEALKKGQLGSLGLDVYENEKSLFFEDKSNEIIQDDVFRRLSACHNVIFTGHQAFLTAEALEAIASTSLLNVQQLLEGVTCPNELKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>B1KG48</accession>
    <name>B1KG48_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Swoo_2478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA86755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012325097.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_2478"/>
    <dbReference type="EnsemblBacteria" id="ACA86755">
        <property type="protein sequence ID" value="ACA86755"/>
        <property type="gene ID" value="Swoo_2478"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_2478"/>
    <dbReference type="HOGENOM" id="CLU_3316875_0_0_6"/>
    <dbReference type="OrthoDB" id="2071499at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACA86755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="41" mass="4623" checksum="FFCCA363D3950EA7" modified="2008-04-29" version="1" precursor="true">MDAGRRYFQWLTYVAVICLFGAIMFATFGEAAILVFKNVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGE2</accession>
    <name>B1KGE2_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_4023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4023"/>
    <dbReference type="EnsemblBacteria" id="ACA88279">
        <property type="protein sequence ID" value="ACA88279"/>
        <property type="gene ID" value="Swoo_4023"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4023"/>
    <dbReference type="eggNOG" id="ENOG5032Y7H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153072_1_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021339">
        <property type="entry name" value="DUF2956"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11169">
        <property type="entry name" value="DUF2956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACA88279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="86" mass="9768" checksum="2FA6AD6A3E40691F" modified="2008-04-29" version="1">MSKEQTKLIAAGIEKGIAEYKKQHKSKARDRDKARKQDIKAKARANADKSEANTEEETDTSSTTQYLPWGLLLLSWAGFIGFYFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGF4</accession>
    <name>B1KGF4_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_4035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA88291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012326620.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_4035"/>
    <dbReference type="EnsemblBacteria" id="ACA88291">
        <property type="protein sequence ID" value="ACA88291"/>
        <property type="gene ID" value="Swoo_4035"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_4035"/>
    <dbReference type="eggNOG" id="ENOG502ZJ22">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2901772_0_0_6"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA88291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="62" mass="7001" checksum="D7176749957EC48F" modified="2008-04-29" version="1">MRKVVIFNKRTNRFFGDVDLTLLNAQIEEMEGEGHEIISVTANTDLFGNLVSFTLLIELSVT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGH0</accession>
    <name>RL27_SHEWM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmA</name>
        <name type="ordered locus">Swoo_1005</name>
    </gene>
    <organism>
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323645.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="B1KGH0"/>
    <dbReference type="SMR" id="B1KGH0"/>
    <dbReference type="STRING" id="392500.Swoo_1005"/>
    <dbReference type="EnsemblBacteria" id="ACA85298">
        <property type="protein sequence ID" value="ACA85298"/>
        <property type="gene ID" value="Swoo_1005"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1005"/>
    <dbReference type="eggNOG" id="COG0211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095424_4_1_6"/>
    <dbReference type="OMA" id="GKDHTLH"/>
    <dbReference type="OrthoDB" id="1904463at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000128809" description="50S ribosomal protein L27">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="84" mass="9049" checksum="3EC5A7B745FE8641" modified="2008-04-29" version="1">MAHKKAGGSTRNGRDSESKRLGVKRFGGESVLAGNIIVRQRGTKFHAGVNVGVGRDHTLFALTDGKVKFEVKGPNNRKFISIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK0</accession>
    <name>B1KGK0_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transketolase central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Swoo_1035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1035"/>
    <dbReference type="EnsemblBacteria" id="ACA85328">
        <property type="protein sequence ID" value="ACA85328"/>
        <property type="gene ID" value="Swoo_1035"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1035"/>
    <dbReference type="eggNOG" id="COG0022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_2_1_6"/>
    <dbReference type="OMA" id="YRNPMVV"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="5">
        <location>
            <begin position="398"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACA85328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="747" mass="82256" checksum="3464A8CE90E9CF2C" modified="2008-04-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>B1KGK1</accession>
    <name>B1KGK1_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">(Acyl-carrier-protein) S-malonyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Swoo_1036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323675.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1036"/>
    <dbReference type="EnsemblBacteria" id="ACA85329">
        <property type="protein sequence ID" value="ACA85329"/>
        <property type="gene ID" value="Swoo_1036"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1036"/>
    <dbReference type="eggNOG" id="COG0331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_806082_0_0_6"/>
    <dbReference type="OMA" id="GNSMGWY"/>
    <dbReference type="OrthoDB" id="780651at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACA85329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002168"/>
        </source>
    </evidence>
    <sequence length="356" mass="38952" checksum="5C06B71C945F5B42" modified="2008-04-29" version="1">MSVETSFDGNKRERVVVIAPGRGCYNKEELGYLHSLHSDKLAFIEGIDAYRKPLQQESIYALDGRDKYSFKLHTAGENASALIYACAMADFMDIDTEKYEIVAVTGNSMGWYIALACVGALDSDGAIDVINTMGSMMQAGLIGGQLIYPEMDEEWKQDKTQRDLIDKAIEQVNDEVGCQVYTSILLGGYRVLAGNEAGLKRLESTLPNIDDRYPMRLYNHGAFHSPLLGDISMRGLASLGEILFSKPSVPLIDGEGGIWTPQSTDIAKLRSYTLGAQVTQTYDFTKAVHVAVKEFAPDKLIVLGPGNTLGGPIAQSLIDIDWFGWGGKSDFSLSQSESPKLLAMGNEQQRQQVVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-04-29" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>B1KH99</accession>
    <name>B1KH99_SHEWM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Swoo_1114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Shewanella woodyi (strain ATCC 51908 / MS32)</name>
        <dbReference type="NCBI Taxonomy" id="392500"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Alteromonadales</taxon>
            <taxon>Shewanellaceae</taxon>
            <taxon>Shewanella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2008-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of Shewanella woodyi ATCC 51908.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Sims D."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Kuske C.R."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Lykidis A."/>
                <person name="Zhao J.-S."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 51908 / MS32</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000961">
        <property type="protein sequence ID" value="ACA85407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012323753.1">
        <property type="nucleotide sequence ID" value="NC_010506.1"/>
    </dbReference>
    <dbReference type="STRING" id="392500.Swoo_1114"/>
    <dbReference type="EnsemblBacteria" id="ACA85407">
        <property type="protein sequence ID" value="ACA85407"/>
        <property type="gene ID" value="Swoo_1114"/>
    </dbReference>
    <dbReference type="KEGG" id="swd:Swoo_1114"/>
    <dbReference type="eggNOG" id="COG0161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_4_3_6"/>
    <dbReference type="OMA" id="PLVPYNA"/>
    <dbReference type="OrthoDB" id="478143at2"/>
    <dbReference type="Proteomes" id="UP000002168">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" va